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1 successfully target HPRT1, the gene encoding hypoxanthine phosphoribosyltransferase-1 (HPRT1), and PO
2 ns were quantified with the micronucleus and hypoxanthine phosphoribosyltransferase forward mutation
3                       For the X-linked human hypoxanthine phosphoribosyltransferase gene (HPRT), this
4 roduced a 146-unit CAG repeat into the mouse hypoxanthine phosphoribosyltransferase gene (Hprt).
5 ene (1-NOP)-induced adducts in exon 3 of the hypoxanthine phosphoribosyltransferase gene at the nucle
6 nstrating targeted correction of a defective hypoxanthine phosphoribosyltransferase gene in hematopoi
7 ed neomycin phosphotransferase genes and the hypoxanthine phosphoribosyltransferase gene were targete
8 lite DNA, telomeric sequences, and the human hypoxanthine phosphoribosyltransferase gene.
9  with a partial duplication within the HPRT (hypoxanthine phosphoribosyltransferase) gene were create
10 tle gene alterations, is based on the use of hypoxanthine phosphoribosyltransferase ( HPRT) minigenes
11                                          The hypoxanthine phosphoribosyltransferase (hprt) encoding r
12                                          The hypoxanthine phosphoribosyltransferase (HPRT) from Trypa
13 evated mutation rates at both the endogenous hypoxanthine phosphoribosyltransferase (Hprt) gene and a
14 e method with mouse ES cells having a mutant hypoxanthine phosphoribosyltransferase (Hprt) gene and g
15 estigate potential mechanisms regulating the hypoxanthine phosphoribosyltransferase (HPRT) gene by X-
16 he transposase enzyme designed to target the hypoxanthine phosphoribosyltransferase (HPRT) gene locat
17 on Willebrand factor (VWF) and Flt-1, to the hypoxanthine phosphoribosyltransferase (Hprt) gene locus
18 )-induced reactivation of the X-linked human hypoxanthine phosphoribosyltransferase (HPRT) gene on th
19       These vectors were introduced into the hypoxanthine phosphoribosyltransferase (hprt) gene to pr
20 cessfully targeted cells by co-targeting the hypoxanthine phosphoribosyltransferase (HPRT) gene.
21 ysis of mutations at the X-chromosome-linked hypoxanthine phosphoribosyltransferase (Hprt) locus and
22  this way are functional, the complete human hypoxanthine phosphoribosyltransferase (HPRT) locus cont
23                                          The hypoxanthine phosphoribosyltransferase (Hprt) locus has
24 nd spectra of somatic mutation events at the hypoxanthine phosphoribosyltransferase (HPRT) locus in p
25 ase-base mismatch and hypermutability at the hypoxanthine phosphoribosyltransferase (HPRT) locus.
26              'In-out' gene targeting using a hypoxanthine phosphoribosyltransferase (HPRT) minigene w
27                                We found that hypoxanthine phosphoribosyltransferase (HPRT) mutation f
28  environment on the frequency of spontaneous hypoxanthine phosphoribosyltransferase (HPRT) mutations
29 mine somatic mutant frequencies (Mfs) at the hypoxanthine phosphoribosyltransferase (HPRT) reporter g
30                                              Hypoxanthine phosphoribosyltransferase (HPRT) salvages 6
31 zed, contained a small amount (381 bp) of 3' hypoxanthine phosphoribosyltransferase (HPRT) sequence a
32 ene, the X-chromosomal disease gene encoding hypoxanthine phosphoribosyltransferase (HPRT), we monito
33 uanine phosphoribosyltransferase (XGPRT) and hypoxanthine phosphoribosyltransferase (HPRT).
34                                              Hypoxanthine phosphoribosyltransferase (HPRT1) is a key
35 le of an invariant aspartic acid (Asp137) in hypoxanthine phosphoribosyltransferases (HPRTs) was exam
36 Enzymes that salvage 6-oxopurines, including hypoxanthine phosphoribosyltransferases (HPRTs), are pot
37 ve a reduced mutation rate at the endogenous hypoxanthine phosphoribosyltransferase locus and extract
38 been inserted immediately 5' to the X-linked hypoxanthine phosphoribosyltransferase locus by a direct
39 endent EGFP reporter gene 5' of the X-linked hypoxanthine phosphoribosyltransferase locus in mouse em
40 g the I alpha exon was replaced with a human hypoxanthine phosphoribosyltransferase minigene by gene
41 inhibition is needed for drugs targeting the hypoxanthine phosphoribosyltransferase of Trypanosoma cr
42 lity of the M. maripaludis hpt gene encoding hypoxanthine phosphoribosyltransferase to confer sensiti
43 cient B cells constitutively expressed human hypoxanthine phosphoribosyltransferase transcripts, they
44 coprotein class I homologue) and HPRT (human hypoxanthine phosphoribosyltransferase), was accomplishe
45  of adenine phosphoribosyltransferase and of hypoxanthine phosphoribosyltransferase were the same in

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