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2 umn used was an XBridge C18 column (50x2.1mm i.d., 2.5microm particle size), and separation was perfo
4 e was packed into a glass column (1.8 x 0.5 (i.d.) cm) and used in on-line chromatographic system.
5 e was packed into a glass column (1.8 x 0.5 (i.d.) cm) and used in the on-line chromatographic determ
7 hibited significantly increased firing after i.d. SLIGRL-NH(2) for 9 min, to partial (25%) tachyphyla
8 m the skin to lymph nodes was observed after i.d., but not after s.c., inoculations, we used the latt
13 nce oligodeoxynucleotide conjugate, i.n. and i.d. IT delivery were similarly effective in modulating
17 asing doses of morphine (5-25 mg/kg, s.c., b.i.d.) and then maintained at 25 mg/kg (b.i.d.) for 4-7 d
21 doses of 237 micromol/kg/day twice a day (b.i.d.), there was serious proximal tubule damage versus 4
22 4 groups: posaconazole 400 mg twice a day (b.i.d.); benznidazole 200 mg + placebo b.i.d.; benznidazol
23 -treated (5 days at 10 mg kg-1 bis in die (b.i.d.)) rats decreased renal blood flow by 46 and 29 % (b
24 r CEP-5214 to CD-1 mice at 23.8 mg/kg/dose b.i.d. resulted in a reversible inhibition of VEGF-R2/FLK-
25 .o. of CEP-7055 at 2.57 to 23.8 mg/kg/dose b.i.d. resulted in dose-related reductions in neovasculari
26 P-7055 at doses of 11.9 to 23.8 mg/kg/dose b.i.d. resulted in significant inhibition (50-90% maximum
27 er, we show that rifampin (75 or 100 mg/kg b.i.d. for 3 d, intraperitoneal) suppressed allodynia indu
29 r providing >99% inhibition at 12.5 mg/kg (b.i.d., orally) in the Leishmania infantum hamster model.
30 odels of contact hypersensitivity (1 mg/kg b.i.d.) and house dust (20 mg/kg q.d.) when dosed orally.
32 nserin (3 mg/kg), or haloperidol (1 mg/kg) b.i.d. 30 min before PCP (2 mg/kg, b.i.d.) for 7 days (day
33 mg/kg) b.i.d. 30 min before PCP (2 mg/kg, b.i.d.) for 7 days (day1-7), followed by a 7-day washout (
34 toneal injection of TRK820 (0.1-10 mug/kg, b.i.d.) significantly inhibited tumor growth by suppressin
36 closporine microemulsion (Neoral) 60 mg/kg/b.i.d. on days +1 to +3 with dose adjusted by blood levels
37 bleeding was lower with dabigatran 110 mg b.i.d. (aHR: 0.60, 95% CI: 0.37 to 0.93) compared with war
38 or placebo (n=2), the second cohort 40 mg b.i.d. (n=6) or placebo (n=2), and the third cohort 40 mg
39 0 mg + placebo b.i.d.; benznidazole 200 mg b.i.d. + posaconazole 400 mg b.i.d.; or placebo 10 mg b.i.
40 on PPI and the dose was increased to 40 mg b.i.d. 31 consecutive patients with typical reflux symptom
42 MMF dosing were 5 to 7 ng/mL and 1,000 mg b.i.d. in groups A and C; 4 to 6 ng/mL and 500 mg b.i.d. i
44 One group received sodium naproxen 550 mg b.i.d. plus placebo for 7 days, while the other group rece
46 saconazole 400 mg b.i.d.; or placebo 10 mg b.i.d. T. cruzi deoxyribonucleic acid was detected by RT-P
50 fen (LDF) alone, 50 mg q.d.; 2) SDD (20 mg b.i.d.) alone; or 3) a combination of SDD plus LDF (combin
52 or future testing on this schedule (350 mg b.i.d.) but also provides the first evidence of successful
54 ces: sequence A (n = 15) Org 26576 (100 mg b.i.d.) for 3 weeks, followed by a 2-week placebo crossove
55 = 18) Org 26576 flexible dose (100-300 mg b.i.d.) for 3 weeks, then 5 weeks placebo; sequence D (n =
56 l human laboratory efficacy of IBUD (50 mg b.i.d.) on primary measures of subjective response to alco
57 ee months of rosiglitazone treatment (4 mg b.i.d.) on whole-body insulin sensitivity and in vivo peri
59 s treated with either vildaglipitin (50 mg b.i.d.) or placebo for 10 days using a double-blind, place
63 cebo followed by 3 weeks Org 26576 (100 mg b.i.d.); sequence C (n = 18) Org 26576 flexible dose (100-
65 as seen with both dabigatran doses (110 mg b.i.d., aHR: 0.24, 95% CI: 0.08 to 0.56; 150 mg b.i.d., aH
66 s lower with both dabigatran doses (110 mg b.i.d., aHR: 0.30, 95% CI: 0.18 to 0.49; 150 mg b.i.d., aH
68 idence interval [CI]: 0.65 to 0.95; 150 mg b.i.d., aHR: 0.57, 95% CI: 0.40 to 0.80), when compared wi
69 y lower with both dabigatran doses (110 mg b.i.d., propensity-match group stratified hazard ratio [aH
70 dazole 200 mg b.i.d. + posaconazole 400 mg b.i.d.; or placebo 10 mg b.i.d. T. cruzi deoxyribonucleic
71 d., 59% (149/253, ROCKET-2) for netarsudil b.i.d., and 8% (17/208, ROCKET-1) to 11% (27/251, ROCKET-2
73 o. t.i.d.; n=19) or acyclovir (200 mg p.o. b.i.d.; n=23) was begun at transplantation and continued f
78 ay (b.i.d.); benznidazole 200 mg + placebo b.i.d.; benznidazole 200 mg b.i.d. + posaconazole 400 mg b
79 rteether as controls, were administered po b.i.d. (128 mg/kg/day) to P. berghei-infected mice on days
86 f a ring electrode ion guide with decreasing i.d. and with a superimposed dc potential gradient along
87 cale containers in which the inner diameter (i.d.) and surface chemistry can be systematically and in
88 specifically a 20 m, 100 mum inner diameter (i.d.) capillary column with a 0.4 mum film thickness to
91 2 to 2 microL/min and column inner diameter (i.d.) from 25 to 75 microm on the relative signal obtain
92 OP) capillary column with an inner diameter (i.d.) of 28 mum and using an on-capillary admittance det
93 interface featuring a large inner diameter (i.d.) separation capillary, and a detachable small i.d.
94 he tumor corresponds to 22.2% injected dose (i.d.) per g of tissue, a value analogous to the most pro
95 ditions of natural route of challenge (i.e., i.d. inoculation), the immune response has the capacity
98 d acute cellular responses in mice following i.d. inoculation of the ear, subcutaneous (s.c.) inocula
99 uch-evoked scratching was observed following i.d. 5-HT (5-hydroxytryptamine), a protease-activated re
102 were pretreated i.v. with human IgG (hIgG), i.d. injections of SpA induced an inflammatory response
104 f independent and identically distributed (i.i.d.) draws does not come from a specified probability d
105 f independent and identically distributed (i.i.d.) random variables, i.e., a Bernoulli sequence.
107 s independent and identically distributed (i.i.d.) samples from the multivariate normal distribution.
109 adhesion events revealed violation of the i.i.d. assumption, depending on the receptor-ligand system
110 y marginalizing the 4( t ) patterns of the i.i.d. model to observed and expected parsimony counts, th
119 tive immunity in macaques after intradermal (i.d.) or intramuscular (i.m.) delivery of 0.5 to 1 mg of
121 termine its efficacy against an intradermal (i.d.) or intranasal (i.n.) challenge with vaccinia virus
122 from intraperitoneal (i.p.) and intradermal (i.d.) challenge by L. interrogans serovar Copenhageni st
124 ared were intranasal (i.n.) and intradermal (i.d.) inoculation of the Francisella tularensis live vac
125 of vaccine by microneedle-based intradermal (i.d.) delivery or intramuscular (i.m.) injection using c
126 luated single versus concurrent intradermal (i.d.) and intramuscular (i.m.) vaccinations as a DNA-pri
128 transmitted in nature following intradermal (i.d.) deposition of parasites by the bite of an infected
129 ous report where we implemented intradermal (i.d.) inoculations to study bacterial dissemination duri
133 of IpaB and IpaD administered intradermally (i.d.) with a double-mutant of the Escherichia coli heat-
134 th 1.2 mg of DNA administered intradermally (i.d.; group A), 1.2 mg of DNA administered intramuscular
135 er 1800 micro g both i.m. and intradermally (i.d.); 9 of 12 patients had humoral (n = 6) and/or T-cel
136 t-knockout (KO) mice infected intradermally (i.d.) or intranasally (i.n.) with LVS succumbed to infec
138 ed with LVS DeltacapB i.n. or intradermally (i.d.) developed humoral and cellular immune responses co
139 , which were administered SpA intradermally (i.d.), do not develop a cutaneous inflammatory response.
140 to mice infected intraperitoneally with IOE, i.d. infection stimulated a stronger protective type-1 c
141 olithic capillary columns (25 cm x 10 microm i.d.) with integrated nanoESI emitters have been develop
142 and Rhodamine 6G, are obtained in 100 microm i.d. fused-silica capillaries under CE conditions using
143 r that moves through a capillary (100 microm i.d.) at a speed approximately 20 cm/s, under laminar fl
144 icides using capillary columns of 100-microm i.d. packed with a 5-microm octadecyl silica (ODS) stati
145 ylate) monoliths were prepared in 150 microm i.d. capillaries using novel binary porogenic solvents c
148 microm i.d. x 360 microm o.d. and 20 microm i.d. x 360 microm o.d. capillaries within the flow rate
149 with a small dispensing aperture (20-microm i.d.) by constriction of a cylindrical piezoelectric ele
152 Fused-silica capillary LC columns (25-microm i.d.) with 3-microm-i.d. integrated electrospray emitter
154 ry, to 5-10 microm, which for a 20-30 microm i.d. capillary results in stable electrospray at approxi
155 ly useful for interfacing narrow (<30 microm i.d.) capillaries and low flow rates (<100 nL/min).
156 ht parallel channels (10 mm long, 360 microm i.d.) connected via external fused-silica capillaries.
157 thick tissue cross section into a 50 microm i.d. capillary where the tissue was solubilized with a s
158 column) were achieved on a 50 cm x 50 microm i.d. column using polycyclic aromatic hydrocarbons and a
159 pray and excellent performance for 50 microm i.d. x 360 microm o.d. and 20 microm i.d. x 360 microm o
162 spectrometry (LC-MS/MS) analyses, 75 microm i.d. x 14 cm capillary columns were interfaced with a co
163 rradiated at 365 nm for 5 min in a 75-microm i.d. capillary to prepare a porous monolithic sol-gel co
164 30-cm-long fused-silica capillary (75-microm i.d.) with dopamine, catechol, and ascorbic acid serving
165 monoliths were synthesized inside 75-microm i.d., UV-transparent fused-silica capillaries by photopo
167 rodialysis membranes (3 mm lengthx200 microm i.d.) have been used to extract volatile analytes from a
168 e complexes are flowed through a 150-microm (i.d.) capillary cell and detected using a low-power He-N
170 on rat mesenteric lymphatics (90-220 microm, i.d.) using servo-controlled wire- and pressure-myograph
171 (styrene-divinylbenzene) (PS-DVB), 10-microm-i.d. porous layer open tubular (PLOT) capillary columns
173 The reactor has been used with 100-microm-i.d. columns with insignificant effects (i.e., <3%) on p
174 producibly resolved by CIEF using 100-microm-i.d. fused-silica capillaries coated with hydroxypropyl
175 retical plates for 75-microm- and 100-microm-i.d. separation capillaries are 1.6 x 10(5) and 2.5 x 10
176 capacities of approximately 10(3)) 15-microm-i.d. capillary liquid chromatography separations (i.e.,
177 y125-cm) and narrow (approximately 15-microm-i.d.) capillary, the four major proteins of the RBC, whi
180 This work explores the use of 20-microm-i.d. polymeric polystyrene-divinylbenzene monolithic nan
181 ith an underivatized, 130-cm-long, 20-microm-i.d., 150-microm-o.d. fused-silica capillary and by moni
182 tomole levels using a 130-cm-long, 20-microm-i.d., 150-microm-o.d. underivatized fused-silica capilla
184 ry LC columns (25-microm i.d.) with 3-microm-i.d. integrated electrospray emitters interfaced to a qu
185 cles were obtained and packed into 30-microm-i.d. fused-silica capillary columns up to 50 cm in lengt
187 -microm porous C18 particle-packed 50-microm-i.d. capillaries were used to speed the RPLC separations
188 capillary lengths (180 cm) with a 50-microm-i.d. capillary (24.5 cm effective capillary length), tot
191 of proteins was carried out using 50-microm-i.d. fused-silica capillaries packed with 5-microm silic
193 ample is deposited directly from a 50-microm-i.d. separation capillary onto the 19-mm ball that is ro
194 ormed on a quadrupole ion trap, a 500-microm-i.d. waveguide was used as a medium to transmit IR radia
195 a MPN film was obtained in a 2-m, 530-microm-i.d. deactivated silica capillary using gravity to force
196 oteolytic peptides for 14.9- and 29.7-microm-i.d. packed capillaries, respectively), the nanoLC/nanoE
198 monolith was synthesized inside a 75-microm-i.d. capillary by photoinitiated copolymerization with w
199 sin I, the carbon fiber emitter in 75-microm-i.d. fused-silica tubing was shown to give ion current c
203 ng a 60-cm fused-silica capillary (50-micron i.d., 35-cm effective length), six of which were detecte
204 ser is focused at the outlet of a 0.6-micron i.d. capillary, producing pulse intensities of approxima
205 its for these toxins separated in 2.1-micron-i.d. capillaries range from 4.4 zmol (approximately 2700
210 ersed-phase separation of peptides on a 1 mm i.d. column operating at flow rate of 50 microL/min.
211 ed in series with a diol column, both 2.1 mm i.d. x 150 mm long, packed with 5-mum spherical silica-b
212 s method uses an immunoaffinity column (1 mm i.d. x 20 mm) for on-line sample cleanup and enrichment,
213 us, we constructed a tubular structure (1 mm i.d.) from aligned human mesenchymal cell sheets (hMSC)
215 (BEH) C18 reversed-phase column (50 x 2.1 mm i.d., 1.7-microm particle size) with gradient elution at
216 ersil C8 HyPurity Advance column (100x2.1 mm i.d., 3 microm) was used with a flow rate of 0.3 ml/min)
217 chieved on a Waters X-Terra C18 (50 x 2.1 mm i.d., 3.5 microm) analytical column with acetonitrile/wa
218 per, we compare a narrow-bore column (2.1-mm i.d.) to a conventional-bore column (4.6 mm i.d.) at ele
222 ng, a 3-micron C18 analytical column (3.2 mm i.d. x 100 mm) for separation, and a membrane introducti
223 chment, a 5-micron C18 trapping column (2 mm i.d. x 20 mm) for analyte focusing, a 3-micron C18 analy
224 ogenic water trap with narrow-bore (<0.20 mm i.d.) transfer lines, and a narrow i.d. open split to th
225 tly anchored to the inner walls of a 0.25 mm i.d. fused silica capillary to produce a sol-gel germani
227 was found that with a 6-meter-long, 0.25-mm i.d. column programmed at a rate of 600 degrees C/min, a
228 capsule and a progesterone capsule (3.35 mm i.d., 4.65 mm o.d., 3.0 cm long) together at 09.00 h on
231 With the use of packed microcolumns (<0.5 mm i.d.), essentially instantaneous heat transfer from the
232 ts each received a silastic capsule (1.57 mm i.d., 3.18 mm o.d., 1.5 cm long) containing estradiol-17
235 i.d.) to a conventional-bore column (4.6 mm i.d.) at elevated temperatures under conditions where th
236 low rate of 15 mL/min with a 5 cm by 4.6 mm (i.d.) column packed with 3 microns polystyrene-coated zi
237 ed columns (lengths 30, 50, 100, and 150 mm, i.d., 1 and 2.1 mm, all packed with Acquity UPLC, BEH-C
238 fraction was extracted in 180 ms by a 2.1-mm-i.d. sandwich microcolumn that contained a 1.1-mm layer
239 ure moves between three heat zones in a 1-mm-i.d., oil-filled capillary using a multielement scattere
242 sure air as carrier gas, a 6-m-long, 0.25-mm-i.d. capillary column can generate approximately 12,500
243 tandem ensemble of two 4.5-m-long x 0.25-mm-i.d. capillary columns with the first using a 0.50-micro
244 ation is performed with a 15-m-long, 0.25-mm-i.d. capillary using a 0.5-microm-thick film of nonpolar
247 nolithic capillary column (16.5 cm x 150 mum i.d.) synthesized from poly(ethylene glycol) diacrylate.
248 s of the RP analytical column down to 25 mum i.d. for an additional 2- to 3-fold improvement in perfo
250 GC x GC separations was a 6 m long, 250 mum i.d. capillary with a PDMS stationary phase, and the sec
252 fiber (50 mum of wall-thickness and 280 mum i.d.), this setup allowed for a continual renewal of the
254 lts were obtained with a capillary of 50 mum i.d. x 50 cm effective length, sodium tetraborate 40 mM
255 te] monoliths were synthesized inside 75 mum i.d. capillaries by one-step UV-initiated copolymerizati
256 e synthesize polymer monoliths inside 75 mum i.d. capillaries, use these monoliths to assemble miniat
259 tic flow through an 11 cm (length) x 50 mum (i.d.) sampling capillary is introduced to a simple micro
261 (<0.20 mm i.d.) transfer lines, and a narrow i.d. open split to the IRMS directly inserted into the c
262 pA in combination with LT-IIb(T13I), a novel i.d. adjuvant of the type II heat-labile enterotoxin fam
263 These results demonstrate the potential of i.d. vaccination with IpaB and IpaD to prevent Shigella
264 Immune T lymphocytes from the spleens of i.d. LVS-vaccinated WT or KO mice controlled intracellul
266 y, mice immunized with LVS DeltacapB i.n. or i.d. and then challenged 6 weeks later by aerosol with 1
269 IO mice, administration of MTII 100 microg q.i.d. i.p. markedly suppressed feeding during the first 4
271 indicate that the more biologically relevant i.d. model of bubonic plague differs significantly from
272 ricted rat mesenteric small arteries (RMSAs, i.d. 200-300 microm) was studied using small vessel myog
274 cal Shwartzman reaction (LSR) after a single i.d. injection of LPS, whereas in the classic LSR, a sec
275 separation capillary, and a detachable small i.d. porous electrospray ionization (ESI) emitter was de
276 ical calculations indicate that even smaller i.d. columns can be used with little effect on chromatog
279 received oral ganciclovir for 6 weeks (2 g t.i.d. for 2 weeks, then 1 g t.i.d. for 4 weeks), and the
280 6 weeks (2 g t.i.d. for 2 weeks, then 1 g t.i.d. for 4 weeks), and the control group received i.v. g
282 on one of two regimes of pindolol (2.5 mg t.i.d. and 5.0 mg t.i.d.) with PET and [11C]WAY-100635.
289 glucosamine at standard doses (500 mg p.o. t.i.d.) in lean (n = 20) and obese (n = 20) subjects.
291 ed to compare addition of 5 mg of pindolol t.i.d. or placebo for 4 weeks to a steady paroxetine dose.
292 hain amino acids (222 mg/kg of body weight t.i.d.) (N=18) and those who received placebo (N=18) in th
295 the magnitude of CD4 T-cell responses in the i.d. group was indistinguishable from those in the other
296 nitude after the DNA vaccinations, while the i.d. group exhibited the responses of the least magnitud
298 ated twice with 20 mug of DNA plus Vaxfectin i.d., 100 mug of DNA plus Vaxfectin i.d., 100 mug of DNA
299 axfectin i.d., 100 mug of DNA plus Vaxfectin i.d., 100 mug of DNA plus Vaxfectin i.m. or 100 mug of D
300 In these studies, single nanotubes with i.d.'s of either 30 or 170 nm were investigated over a r
301 amma production, however, was seen only with i.d. and i.l. routes of administration, and no IL-4 resp
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