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1 l-vein bleeding time, which were reversed by idarucizumab.
2                                              Idarucizumab (1 g, 2 g, or 4 g 5-min infusion, or 5 g pl
3 m analysis included 90 patients who received idarucizumab (51 patients in group A and 39 in group B).
4 for dTT was 1.01 with placebo, 0.26 with 1 g idarucizumab (74% reduction), 0.06 with 2 g idarucizumab
5  idarucizumab (74% reduction), 0.06 with 2 g idarucizumab (94% reduction), 0.02 with 4 g idarucizumab
6  idarucizumab (94% reduction), 0.02 with 4 g idarucizumab (98% reduction), and 0.01 with 5 g plus 2.5
7 98% reduction), and 0.01 with 5 g plus 2.5 g idarucizumab (99% reduction).
8                                              Idarucizumab, a monoclonal antibody fragment, was develo
9 ombotic event occurred within 72 hours after idarucizumab administration in a patient in whom anticoa
10                  We examined the efficacy of idarucizumab, an antibody fragment binding to dabigatran
11                                              Idarucizumab, an antibody fragment, was developed to rev
12 o determine the safety of 5 g of intravenous idarucizumab and its capacity to reverse the anticoagula
13  5 g plus 2.5 g idarucizumab groups (nine to idarucizumab and three to placebo in each group), and 11
14 ed into the 4 g idarucizumab group (eight to idarucizumab and three to placebo).
15                                              Idarucizumab completely reversed the anticoagulant effec
16 roved humanized monoclonal antibody fragment idarucizumab for reversing the effects of dabigatran, th
17 ability, and efficacy of increasing doses of idarucizumab for the reversal of anticoagulant effects o
18 ch group), and 11 were enrolled into the 4 g idarucizumab group (eight to idarucizumab and three to p
19  and hot flushes), one in the 5 g plus 2.5 g idarucizumab group (epistaxis); one receiving placebo (i
20 ported in seven participants: one in the 1 g idarucizumab group (infusion site erythema and hot flush
21 into each of the 1 g, 2 g, or 5 g plus 2.5 g idarucizumab groups (nine to idarucizumab and three to p
22                                              Idarucizumab immediately and completely reversed dabigat
23                                              Idarucizumab in equimolar dose prevented excess hematoma
24                                              Idarucizumab is a monoclonal antibody fragment that bind
25                                              Idarucizumab is available as an antidote to rapidly reve
26                                              Idarucizumab normalized the test results in 88 to 98% of
27 n within 4 hours after the administration of idarucizumab, on the basis of the determination at a cen
28 n within 4 hours after the administration of idarucizumab, on the basis of the diluted thrombin time
29 mly assigned within groups in a 3:1 ratio to idarucizumab or placebo using a pseudorandom number gene
30                                        Thus, idarucizumab prevents excess intracerebral hematoma form
31                     In emergency situations, idarucizumab rapidly, durably, and safely reversed the a
32                       In more extensive ICH, idarucizumab significantly reduced mortality.
33              These phase 1 results show that idarucizumab was associated with immediate, complete, an
34 tudy to determine whether 5 g of intravenous idarucizumab would be able to reverse the anticoagulant

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