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1 (68)Ga radiopharmaceuticals do not meet this ideal.
2 at high pressures and the solution is nearly ideal.
3 , media is the more likely predictor of body ideals.
4 le, reviving and better observing scientific ideals.
5 Association criteria for ideal activity (11% ideal, 14% intermediate, 75% poor).
6  met American Heart Association criteria for ideal activity (11% ideal, 14% intermediate, 75% poor).
7 e present work examined the applicability of Ideal Adsorbed Solution Theory (IAST), a prevailing ther
8                                          The Ideal Adsorbed Solution Theory-Equivalent Background Com
9                                          The ideal age to introduce egg into the infant diet has been
10 nces of efforts to reduce alert fatigue, and ideal alert quantity.
11 rops, or marginal land, is often promoted as ideal, although there is a poor understanding of the qua
12 s describe a discrepancy between scientists' ideals and practices when working with stakeholders.
13 ically textured nanoscale grain structure is ideal; and this conventionally requires expensive "die u
14                              Hamsters are an ideal animal model for a variety of biomedical research
15 s hAS transgenic mouse model is therefore an ideal animal model for hypertension therapy studies.
16 um metal-based batteries.Lithium metal is an ideal anode material for rechargeable batteries but suff
17                              Reckoned as the ideal anode, however, Li has many challenges when direct
18                             Automation is an ideal approach for high-throughput sample preparation.
19 ription of a single-copy gene in vivo is the ideal approach to study this problem.
20                                           An ideal approach would support three-dimensional (3D) tiss
21 n achieve gigantic shape change, making them ideal as a platform for super light-weight structures, s
22 le printable formulations are still far from ideal as they are either based on toxic solvents, have l
23                    To address this issue, an ideal assay involving membrane components would (1) mimi
24 s to boost the laser power and maintain near ideal balanced performance across the whole optical band
25                      However, development of ideal bandgap (1.3-1.4 eV) absorbers is pivotal to furth
26 uminescence and photovoltaic analysis, a new ideal bandgap (1.35 eV) absorber composition (MAPb0.5 Sn
27 orm for unleashing the complete potential of ideal bandgap PVSCs and prospects for further improvemen
28                                              Ideal bandgap PVSCs are currently hindered by the poor o
29               We compared performance to the ideal Bayesian learner and several suboptimal models tha
30 ctive serotonin reuptake inhibitors, are not ideal because only a fraction of patients achieve remiss
31 nventional statistical methods are less than ideal because they either fail to select relevant genes,
32                                          The ideal biomaterial should promote attachment, proliferati
33                               Achievement of ideal blood pressure, ideal body mass index, ideal gluco
34 nce in crystal chemistry and are regarded as ideal blueprints for the rational design and constructio
35         Achievement of ideal blood pressure, ideal body mass index, ideal glucose control, and nonsmo
36 d-expiratory lung volume (30.4 +/- 9.1 mL/kg ideal body weight) and oxygenation (273.4 +/- 72.1 mm Hg
37                Low tidal volume (2.9-4 ml/kg ideal body weight) and poor compliance (12.1-18.7 ml/cm
38 ncer received IMGN853 at 6.0 mg/kg (adjusted ideal body weight) once every 3 weeks.
39 geneity in net transition probabilities from ideal BP emerge during childhood, with associated rapid
40 childhood, with associated rapid declines in ideal BP observed in boys and African Americans, thus in
41 a net 2.9% (95% CI, 2.3%-3.4%) of those with ideal BP transitioned to prehypertension 1 year later.
42 ge 8 years, disparities in the prevalence of ideal BP were observed, with the prevalence being lower
43  (n = 3888) populations transitioned between ideal BP, prehypertension, and hypertension across the l
44 sembled sequentially [10-14], making this an ideal brain region for investigating the circuit-level i
45 W48O184](40-) (abbreviated as {P8W48}) is an ideal building block for the construction of intrinsical
46 inate the dependency on immunosuppression is ideal, but remains challenging.
47       Human polyclonal antibodies (PAbs) are ideal, but this is dependent upon serum from convalescen
48 d graphene-enabled Zika biosensor make it an ideal candidate for development as a medical diagnostic
49 radual emission enhancement which makes R an ideal candidate for monitoring of Ag(+) in physiological
50 d alertness for visuomotor control and is an ideal candidate for objective measurement of visuomotor
51 IPY-based chemodosimetric reagent make it an ideal candidate for use as a reagent for super-resolutio
52                      Grid cells represent an ideal candidate to investigate the allocentric determina
53 s, expressed recombinantly as VLPs, could be ideal candidate vaccines for a polio-free world.
54 ophin-regulated pathways, making AR agonists ideal candidates for combination approaches.
55 s of genes have predisposed miRNAs to become ideal candidates for drug delivery and tissue regenerati
56 and nanoelectromechanical systems (NEMS) are ideal candidates for exploring quantum fluids, since the
57 ion, glaucoma, and diabetic retinopathy, are ideal candidates for home monitoring practice integratio
58  of catechins and other flavonoids make them ideal candidates for nanoformulations to be used in anti
59                                     ASOs are ideal candidates for the treatment of neurodegenerative
60  classified as having poor, intermediate, or ideal cardiovascular health based on the number of favor
61  METHODS AND We measured the Life's Simple 7 ideal cardiovascular health metrics in 4195 blacks in th
62                                          The ideal cardiovascular health score (ICHS) is recommended
63  that the corresponding macrocyclases may be ideal catalysts for production of cyclic peptides.
64 n induced pluripotent stem cells (iPSCs) are ideal cell sources for personalized cell therapies since
65 t demonstrated linear optical isolation with ideal characteristics over a microscale footprint - simu
66 ransfer from adjacent materials, making them ideal charge-transport layers in phototransistor devices
67 ced sensor performance make our biosensor an ideal choice for point of care diagnostics and personal
68 ropagation using the device properties reach ideal classification accuracy.
69  and sponsors struggle with choosing between ideal clinical trial designs and more practical ones.
70 tivity, the picture of space-time assigns an ideal clock to each world line.
71 ton probe, beyond what is achievable with an ideal coherent state (a perfect laser) detected with 100
72 ibility and affordability of providing these ideal conditions for plasma genotyping in resource-const
73     Together, we systematically describe the ideal conditions to accurately and reliably measure DA t
74 s invites considerable complexity even under ideal conditions.
75 t the heart of iron physiology, providing an ideal context to discuss recent progress in understandin
76     The hydrogen atom is considered to be an ideal coupling handle, owing to its relative abundance i
77                                  Maize is an ideal crop for GWAS and significant progress has been ma
78  for producing these effects, the INaP is an ideal current for boosting the amplitude and duration of
79       This study analyzed the association of ideal CVH with mortality, incident coronary heart diseas
80 , and other nonmodel echinoderms provides an ideal dataset with which to explore GRN evolution in a c
81                        Cellulose paper is an ideal diagnostic platform for low-cost, easily disposabl
82 art in cancer diagnosis and treatment is not ideal; diagnostic tests are accurate but invasive, and t
83 uality factor n of 1.6 (where n = 1.0 for an ideal diode), compared with a value of 3.1 for a polycry
84 ating blood vessels, making it a potentially ideal dual-compartment therapeutic target.
85 acid aptamer recognition comes close to this ideal due to the ease of multiplexing, without the need
86                                 However, the ideal duration of treatment with interferon-free regimen
87 ition arises between maintaining the overall ideal electron concentration and accommodating the diffe
88            Fusion reactor is one of the most ideal energy resources to defeat the environmental degra
89 ildren were classified as having grown up in ideal environments if they 1) had access to safe water a
90 e found when less restrictive definitions of ideal environments were used.
91       We compared the heights of children in ideal environments with those in the WHO reference sampl
92                                           An ideal epidemiologic study would monitor both groups equa
93 e Saccharomyces cerevisiae OST, making it an ideal experimental system to study the fundamental prope
94                                To obtain the ideal extraction condition, was used Response Surface Me
95 ce in HOCl sensing, such as high brightness, ideal far-red to NIR optical window, excellent photostab
96 ture Selection (GBFS) in order to select the ideal feature set for each BL classification.
97  low resource settings, WHO summarized their ideal features under the acronym ASSURED (Affordable, Se
98                             Partnering is an ideal field if someone is seeking to move from a scienti
99 ynamics to cope with fast motion [6], so the ideal filtering would additionally be spatial.
100                                          The IDEAL fitting in phantom data with superimposed noise pr
101 olecular magnetization transfer effects, the IDEAL fitting revealed pronounced negative contrasts of
102                       We further applied the IDEAL fitting to quantify CEST MRI in rat gliomas and co
103 wnsampling Expedited Adaptive Least-squares (IDEAL) fitting algorithm that quantifies CEST images bas
104 ically accurate proteins by using so-called "ideal" folds rich in regular secondary structures and al
105 ightweight materials recently discovered and ideal for advanced multifunctional applications.
106 m transistor provides a solid-state platform ideal for all-optical networks and quantum networks.
107 ng mutations, making MLL-FP driven leukemias ideal for animal modeling.
108  to discover design and operation conditions ideal for cell health.
109 icroscopies have low resolution which is not ideal for cellular force mapping in small platelets.
110                                    It may be ideal for certain applications, such as reconstructing p
111 te between short- and long-germ development, ideal for comparative study of PRGs.
112 mediate levels of nonmotor cross-linkers are ideal for contractility; in vivo, intermediate levels of
113 routes, and processing versatility make MHPs ideal for cost-efficient, large-volume manufacturing of
114 implementing parallel computation - a set up ideal for deployment on computing clusters.
115        For example, the decerebrate mouse is ideal for examining locomotor behavior using intracellul
116                          SL-seq is therefore ideal for fast and massive parallel sequencing of parasi
117 ese habitats are characterized by conditions ideal for foliar bacteria, which can be potent plant pat
118 d giant unilamellar vesicles (GUVs) would be ideal for in vitro electrophysiology, but efforts to mea
119            A role in portfolio management is ideal for individuals who enjoy tackling challenges that
120 - or alternating-polarity ion pulses, and is ideal for inducing nanoelectrospray ionization (nanoESI)
121    [Leu(3), Leu(7), Phe(8)]-gamma-MSH-NH2 is ideal for inducing short-term skin pigmentation without
122 ges of QUENCHER and confirmed this method as ideal for industrial applications.
123 a variety of operating conditions, making it ideal for integration with existing microfluidic devices
124 brations of molecular bonds and is therefore ideal for label-free detection of chemical species.
125 t it can form an amphipathic helix, which is ideal for lipid membrane interaction.
126                          Thus, the system is ideal for on-site monitoring, and the real-time quality
127          A half-life of 12-48 h is generally ideal for once daily dosing of oral drugs.
128 been documented in literature, they are less ideal for one or several reasons including slow kinetics
129 hoice in high-risk patients and is therefore ideal for patients with advanced chronic kidney disease,
130 , a radionuclide with a half-life of 12.7 h, ideal for PET imaging.
131                        Although DBS might be ideal for POC, this is the first report of using an SPR
132 s unique performance characteristics make it ideal for population screening; its application to the M
133        The new cell retention device is thus ideal for rapid perfusion process development in a bioma
134 res no sample preparation, thereby making it ideal for rapid sampling of thicker tissue sections for
135                  Semiconductor nanowires are ideal for realizing various low-dimensional quantum devi
136                     This novel worm model is ideal for screening molecules and genes to identify thos
137 olated compartments of tiny volumes that are ideal for single cell or single molecule assays, (ii) ra
138  film, absorber layers with 1.55 eV bandgap, ideal for single-junction PV, have been achieved within
139                  Such a light source is also ideal for space communications, both in the classical an
140 trol suggesting that this temperature may be ideal for storage of CES.
141    The cichlid fish Astatotilapia burtoni is ideal for studying the neural regulation of feeding and
142 xide thermoelectric materials are considered ideal for such applications.
143 p for immobilizing biomolecules; thus, it is ideal for the fabrication of biosensors.
144                              It is therefore ideal for the isolation and preconcentration of single c
145 rectly into focally afflicted tissues is the ideal for the treatment of diseases that require direct
146 e has a multivalley band structure, which is ideal for thermoelectrics and also promotes the formatio
147                      Small invertebrates are ideal for these large-scale studies; however, patch-clam
148            Sources of quantum noise are thus ideal for this application due to their intrinsic uncert
149                            FNIII domains are ideal for this study because they have an identical seve
150 ed edge-transitive nets such shp and alb are ideal for topological transplantation and deliberate con
151 reen" molecular hosts have also been used as ideal functional molecules to improve the solubility, st
152                                          The ideal future goal of treatment is to eradicate chronic H
153 measured and theoretical values based on the ideal gas law were comparable.
154                                           An ideal generic cancer immunotherapy should mobilize the i
155 ideal blood pressure, ideal body mass index, ideal glucose control, and nonsmoking was associated wit
156  utility scores ranging from 0 [death] to 1 [ideal health]).
157 on platforms in mammalian cells are far from ideal, hindering the study of human gene variants in the
158  were classified as having been raised in an ideal home environment.
159 ort-range magnetism combined with the nearly ideal honeycomb structure places Cu2IrO3 closer to a Kit
160                               Pigs represent ideal human disease models due to their similar size, an
161                             DD represents an ideal human model disease for fibrosis research.
162 d risk of myocardial infarction, provides an ideal human model to study inflammatory atherogenesis in
163 d by standard Shannon sampling arguments for ideal images and is also robust to noise.
164 important progress toward the realization of ideal implantable electrical probes allowing for mapping
165 ofile, but no single regimen is likely to be ideal in all respects.
166 ise from reconnection, or jets arise from an ideal instability.
167 acturers (mDIXON Quant [Philips Healthcare], IDEAL IQ [GE Healthcare]).
168 unit (ICC, 0.992; 95% CI: 0.986, 0.996), and IDEAL IQ and the GE 3.0-T unit (ICC, 0.966; 95% CI: 0.93
169         While an embryo-specific promoter is ideal it may not be essential for assembling an effectiv
170 icular, in subjects with >/=5 metrics at the ideal level (compared with those with </=2), there was a
171  of the participants had >/=5 metrics at the ideal level.
172                       Among individuals with ideal levels for 3-4 of these 4 cardiometabolic biomarke
173 nteraction distance that goes to zero in the ideal limit irrespective of the physical distance.
174 k-shell Fe3 O4 @Au NPs can be regarded as an ideal magnetic-plasmonic theranostic platform for magnet
175        Hence, a major innovation in creating ideal maize plant architecture originated from ectopic o
176 orption coefficient, gallium phosphide is an ideal material for photonic structures targeted at the v
177 edral angles, validating that the host is an ideal means to study the elusive axial/diaxial conformer
178                     The limited size of this ideal melting zone explains the low number of LIVS typic
179  the lightning discharge channel there is an ideal melting zone that represents roughly 10% or less o
180 ubjects with 3 to 4 and subjects with 5 to 7 ideal metrics with those with 0 to 2 ideal metrics, resp
181  5 to 7 ideal metrics with those with 0 to 2 ideal metrics, respectively.
182 ar events decreased across the categories of ideal metrics.
183  to a binary ligand shell that behaves as an ideal mixture and that has a composition matching the ov
184                           This makes them an ideal model for GDM.
185 ifferentiate into spermatozoa, represents an ideal model for studying post-transcriptional regulation
186 s in the meiotic program, A. rhodensis is an ideal model for studying the plasticity of meiosis and h
187                         The gypsy moth is an ideal model of how important ecological questions can be
188  is a recent allotetraploid and, thus, is an ideal model organism for studying early changes followin
189  circulation at rest and during exercise, an ideal model system characterized by physiological extrem
190 p highly stable over one year, presenting an ideal model system for investigating the HER catalytic a
191 tococcus mutans Cid/Lrg system represents an ideal model to study how this organism withstands variou
192 PB is analogous to centrosomes, making it an ideal model to study MTOC assembly.
193 parently associated with perturbations to an ideal model.
194 icity of renin activity, transgenic mice are ideal models for experimentally investigating and manipu
195    These 'resurrection species' may serve as ideal models for the ultimate design of crops with enhan
196         Neotropical crater lake cichlids are ideal models to study evolutionary processes as they dis
197 ive research endeavors are pursued to target ideal molecular sieves among diverse porous materials, o
198 us materials, over the past several decades, ideal molecular sieves for the separation and purificati
199                                   BAFF is an ideal molecule to improve early pathways of B cell activ
200 nced and well-annotated genome, making it an ideal monocot model for addressing vascularization and b
201                                           An ideal neural device enables long-term, sensitive, and se
202 t mechanisms: coronal mass ejections from an ideal (non-dissipative) process, whereby the energy rele
203 eneral surgery procedures and to estimate an ideal number of pills to prescribe.
204 lysis (AMA) is a recently developed Bayesian ideal observer method for task-specific dimensionality r
205                                           An ideal observer will give equivalent weight to sources of
206 ly followed the predictions derived from the ideal observer.
207                      Here, using fMRI and an ideal-observer analysis, we demonstrate that the brain's
208  to estimate subjective predictions under an ideal-observer model.
209 and improvement are necessary to achieve the ideal of a noninvasive image-based measure of renal fibr
210 igh-resolution spectroscopy, which offers an ideal opportunity for judicious comparison between theor
211 ar habitats by different species provides an ideal opportunity to identify genes underlying adaptatio
212 ose was determined using 2 formulas based on ideal or actual body weight.
213 ronoamperometry and cyclic voltammetry of an ideal outer-sphere redox probe, reversible ferrocene met
214 ct comparison with previous estimates is not ideal owing to methodological differences, our results a
215 t) was categorized as poor, intermediate, or ideal PA with American Heart Association criteria.
216                      CE x muFFE generated an ideal peak capacity of 1885 in a 2.7 min separation of f
217  results in the so-called Dirac cone for the ideal, perfectly ordered crystal structure.
218                               Herein, a near-ideal plasmon-mediated photocatalyst system is developed
219      Finally, we describe the features of an ideal platform and provide a roadmap to facilitate the e
220 wn transparent conductive oxide, it is a non-ideal platform for biofilm growth.
221 and deubiquitinating (DUB) enzymes offers an ideal platform for modulating activity via allostery.
222  early renal angioblasts that may provide an ideal platform for the investigation of renal vasculogen
223  time-reversal symmetry, thus offering us an ideal platform to study magnetic Weyl fermions in a cent
224 e, phonons) in their surroundings and are an ideal platform to study the properties of hybrid optical
225                                   Herein, an ideal porous material, SIFSIX-14-Cu-i (also termed as UT
226 ntitatively assessing the probe efficacy; an ideal probe exhibits high reactivity with its protein ta
227 ) then magnetic reconnection (rather than an ideal process) must also underlie mass ejections, and th
228 ant property of a quantum processor, with an ideal processor having random access-the ability of arbi
229 100 reefs of the GBR, or around 3%, have the ideal properties to facilitate recovery of disturbed are
230 s significantly differently than thermal and ideal quantum annealers.
231 f 93 keV (just above the K-edge of gold), an ideal radioisotope for such purposes.
232 t allowed us to discern two properties of an ideal RAF inhibitor: high-binding affinity to all RAF pa
233 cation-targeting PET imaging agent, using an ideal rat model.
234 issues based on deeper principles and shared ideals rather than self-interest or adherence to laws an
235 d experiments to accelerate the selection of ideal reaction conditions and activating agents for the
236 thesis of acetic acid from CH4 and CO2 is an ideal reaction with 100 % atom economy, but it is almost
237       Consequently, ligand-free colloids are ideal reference materials for evaluating the effects of
238 )-doped BaSnO3 (LBSO) perovskite would be an ideal replacement given its electron mobility and electr
239 zyme lignin (SREL) has been identified as an ideal representative for native lignin in the plant wall
240 lose II, was competent to prepare SREL as an ideal representative for the protolignin.
241                            Though lacking in ideal resolution, in vitro binding of the PD-sauvagine r
242 lator model that permitted derivation of the ideal responses of the circadian regulation of starch br
243 s estimated from Salmon and Kallisto are the ideal RNA-seq measurements for deconvolution studies.
244  spread, weak links in the network can offer ideal routes for hospital-associated pathogens to travel
245                                          The ideal screening test should be inexpensive, well tolerat
246                   No consensus regarding the ideal sedation treatment for stroke endovascular therapy
247 nanoparticle-structured MoS2 nanosheet as an ideal semiconductor interface, which is able to form a h
248                 Oceanic archipelagos are the ideal setting for investigating processes that shape spe
249 lculated, from which characteristics such as ideal shear stress, the dislocation Burgers vector, and
250            Comparison of energy barriers and ideal shear stresses suggests that the favorable modes a
251   The fission yeast actin cytoskeleton is an ideal, simplified system to investigate fundamental mech
252 inone/ferrocyanide redox battery with a high ideal solar-to-chemical conversion efficiency of 3.0% wi
253 rong DMSO-water interactions (<30 mol %), 2) ideal-solution-like (30-90 mol %), and 3) self-interacti
254 s), including metaldehyde (Met), provides an ideal space for determining the characteristics and util
255 igh production yield and stability make them ideal specificity-conferring building blocks for the des
256 ular (CV) disorders is often lacking because ideal specimens (ie, whole blood) are not retained routi
257 TT) has important cellular functions, so the ideal strategy would selectively lower mutant HTT while
258 e endospore-former, Bacillus subtilis, is an ideal subject for laboratory evolution experiments.
259                  These nanosheets provide an ideal substrate for the engineering of guest components
260 c fermented to produce volatile fatty acids, ideal substrate to feed aerobic bacteria and produce mor
261 arge current on/off ratios (>10(6)) and near-ideal subthreshold swing values ( approximately 65 mV de
262 hed H chain isotype are critical to generate ideal surrogate Abs for testing immuno-oncology mechanis
263 ent in the HeLa-micros model, it provides an ideal system for dissecting the intricacies of how the U
264 re general terms, huddling is proposed as an ideal system for investigating the interaction between s
265 st that chicken gustatory tissue provides an ideal system for multidisciplinary studies, including or
266   The programmable nature of DNA makes it an ideal system for rationally constructing self-assembled
267 vels of B cells and antibodies, making NP an ideal system for studying B cells in the airways.
268                    The ascidian embryo is an ideal system to investigate how cell position is determi
269 es and associated defect clusters, represent ideal systems to study and understand intrinsic defects
270 ycine branch to triglycine on Lipid II as an ideal target for small molecules that restore sensitivit
271 traprostatic tissues, and thus represents an ideal target for the diagnosis and management of prostat
272 ils, mast cells, and basophils, making it an ideal target for the treatment of diseases involving the
273          In a step toward developing such an ideal target-based analytical assay for membrane compone
274               Early developmental stages are ideal targets for amphibian bacterial therapy that can g
275 r transmission to a new host, making the SGs ideal targets for genetic strategies to block transmissi
276  circulating tumor cells (CTCs), making them ideal targets to noninvasively profile the molecular fea
277 4 intermediate, and C4 species, making it an ideal taxon with which to study the evolution of C4 phot
278 orizontal scattering plane which makes it an ideal technique for fast mapping and parametric studies
279   Vibrational spectroscopy is potentially an ideal technique toward the characterization of the micro
280 e bilayer environment and are, therefore, an ideal test case for exploring membrane protein coupling.
281 ulated under a graphene cover that offers an ideal testbed to explore its molecular structures and th
282                     Thus, Dyrk1A might be an ideal therapeutic target for Alzheimer's disease, especi
283 ations, WSe2 and MoSe2 are identified as two ideal TMDs (using the reported experimental material's p
284 en aged 8 to 30 years experienced the lowest ideal to prehypertension net transition probabilities (0
285 Mexican American women exhibited the largest ideal to prehypertension net transition probabilities af
286                          After age 40 years, ideal to prehypertension net transition probabilities st
287 t properties of neural circuits, it would be ideal to record the activity of every neuron in a behavi
288 ng-lasting patterning of habitats makes them ideal to test the role of environmental pressure in driv
289 le low price of the laser source made it the ideal tool for N2O analyses of the off-gas of a wastewat
290            Intravital microscopy (IVM) is an ideal tool to provide the spatial and temporal resolutio
291 ccumulation (15.6 %ID g(-1) , 72 h p.i.) and ideal tumor-to-muscle ratio (16.6, 72 h p.i.) was achiev
292                        Cr2Ge2Te6 is a nearly ideal two-dimensional Heisenberg ferromagnet and so will
293 ly, high-mobility graphene has emerged as an ideal two-dimensional semimetal that hosts unique chiral
294 h evidence from practice by building on four ideal types of SI in science.
295                                          The ideal use of the Ultra cartridge may therefore involve a
296 ) 4B-P38G mutant has several features for an ideal vaccine candidate, including significantly reduced
297 tained at room temperature so as to preserve ideal vacuum conditions, represent concrete alternatives
298                           Until recently, no ideal valid, feasible, and reliable scar scale existed t
299 s that the pumping current deviates from the ideal value by only about 20 ppm at the flattest part of
300                          The zebrafish is an ideal vertebrate model to address this challenge, thanks

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