ライフサイエンスコーパス: identify

1 ith the highest average yearly citation were identified.

2 signment of the natural product serratin was identified.

3 ormed by various reactions, and 18 BTPs were identified.

4 s essential to these activities remain to be identified.

5 1 cancer patients between 1950 and 2011 were identified.

6 nt palladacyclic dimer intermediate has been identified.

7 ient patient-reported pain trajectories were identified: (1) persistently low, (2) mild, (3) moderate

8 We retrospectively identified 10 patients who underwent clinically indicate

9 We identified 1044 patients, among whom 460 (44.1%) receive

10 earch of Pubmed, PsycINFO and Web of Science identified 13 articles encompassing a sample of 1693 ind

11 Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, includ

12 ipients data from June 2013 to June 2015, we identified 1768 DD livers exported to regional candidate

13 However, we identified 2 or more missense variants predicted to be d

14 be contributions to folding and binding, and identified 2,618 high-affinity binders.

15 18 833 children with clinical pneumonia and identified 2156 cases of radiological pneumonia.

16 In the combined meta-analysis, we identified 22 loci associated at genome-wide significanc

17 We identified 26 ancient and more recent polyploidy events

18 We identified 265 specimens to species or genus using DNA b

19 We identified 31 cases of PTLD during the study period.

20 KEY MESSAGE: We have identified 39 proteins that interact directly or indirec

21 We identified 57 longitudinal studies exploring the associa

22 ing a LC-MS/MS "cold tracer" method, we have identified 8 (PF-06445974) as a promising PET lead.

23 We identified 89,790 incident PD cases and 118,095 comparab

24 th of the intestine from fish to mammals and identified a core set of genes comprising a vertebrate I

25 ize known major antigenic sites in MeV-H, we identified a D4 genotype variant that escapes neutraliza

26 We recently identified a defect in repetitive firing of lower motor

27 We identified a feedback loop within the NANCI (Nkx2.1-asso

28 Our studies identified a highly up-regulated mammalian lncRNA, FOXD3

29 RNA-seq analysis of whole skin identified a larger number of psoriasis-increased differ

30 er, by using mutated promoter constructs, we identified a NF-kappaB site as critical in this activati

31 We identified a novel splice mutation in IKBKG (c.518+2T>G,

32 We have identified a number of neuropeptide signaling systems wi

33 Previously, we identified a potent neutralizing antitoxin against BoNT/

34 Whole exome sequencing identified a single mutation in SLC30A9 within this locu

35 Overall, we identified a small number of immunodominant regions, whi

36 Instead, we identified a specific set of markers associated with the

37 functions after their initial activation and identifies a novel mechanism for controlling thrombosis.

38 Our study identifies a potential "two-hit" mechanism in which tau

39 We identify a conserved region in the Ulp2 C terminus that

40 We also used strict criteria to identify a large set (649) of novel, evolutionarily rest

41 We further identify a naturally polymorphic site at Nef position 9

42 ation with sequencing and RNA sequencing, we identify a novel B-lymphoid program for transcriptional

43 Taken together, these findings identify a novel mechanism linking IL-6 trans-signaling

44 Here, we identify a presynaptic effector molecule of the Wingless

45 By contrast, we identify a pull-push inhibitory circuit in frontal corte

46 In this issue of JEM, Marciniak et al. identify a putative novel function of tau protein as a r

47 Cumulatively, we identify a signaling cascade that provokes structural re

48 ng gene expression and mutation profiles, we identify a unique subpopulation based on addiction to th

49 ssion and causes a human skeletal dysplasia, identifying a mechanism that regulates chondrogenesis vi

50 d to engineering and screening approaches to identify activators and blockers with strong, specific b

51 To identify active sites, we first predict the CO binding a

52 Together, this work identifies Actr10 as a factor necessary for dynactin-mit

53 ysis including >300,000 European samples, we identified an additional nine novel loci.

54 We identified an atherosclerosis-associated single-nucleoti

55 By cDNA library screening, we identified an immune cell-specific, co-stimulatory recep

56 Here, we identified an orphan protein (Plu2236) from Photorhabdus

57 perform a genome-wide association study and identify an association between a variant within a Matri

58 o transduction of mouse organotypic explants identified Anc80L65 from a set of other adeno-associated

59 iversification centers of Espeletia are also identified and a comprehensive phytochemical characteriz

60 to an urban trauma center (recidivists) were identified and compared with those with single admission

61 called CANE developed in our laboratory, we identified and selectively labeled noxious-stimulus-acti

62 Last, we identified and studied three novel patient XIAP mutation

63 We have identified and validated multiple TFs influencing asthma

64 ilize in situ spectroscopy and microscopy to identify and characterize a support effect in oxide-supp

65 Finally, we identify and compare appropriate tunable-by-doping mater

66 mprove the accuracy and speed of analyses to identify and prevent spill risks and mitigate potential

67 ing pancreas lineage specification have been identified, and Notch signalling has been implicated in

68 nd differentiation of repair cells will help identify, and eventually correct, the failures that lead

69 based proximity ligation assay (polyPLA), to identify antigenic variants of subtype H3N2 swine IAVs.

70 Genetic association studies to date have not identified any robust risk loci for diabetic retinopathy

71 We identified Arabidopsis pex6 and pex26 mutants by screeni

72 2-Methylquinoline has now been identified as a feasible ligand that can coordinate to t

73 Finally, SNP rs11265269 was identified as a risk factor of BPD (OR 1.8, p = 5.3 x 10

74 ltransferase 60 (Naa60 or NatF) was recently identified as an unconventional N-terminal acetyltransfe

75 and increases in Ruminococcus and Dorea were identified as gut microbiota signatures of NAFL onset an

76 macrophage proliferation and glycolysis were identified as hallmarks that correlated with clinical di

77 970nm (associated with water) were generally identified as important features throughout the study.

78 oEL, a homolog of heat shock protein 60, was identified as one of the factors responsible for inducin

79 Indirubins have been identified as potent ATP-competitive protein kinase inhi

80 ic polypeptide (APOBEC) 3 proteins have been identified as potent viral DNA mutators and have broad a

81 techniques, two different intermediates were identified as responsible for the change in selectivity

82 and microvascular obstruction >/=1.4%LV were identified as the best cutoff values for MACE prediction

83 These granules have been identified as those of Solanum jamesii Torr.

84 However, experimental methods to identify associations between lncRNAs and diseases are e

85 Using genome-wide association analysis, we identify associations between several candidate genes an

86 We identified autophagy as a pivotal cell response determin

87 oxia using diffusion tensor imaging (DTI) to identify axonal injury distant from contusions.

88 d, maladapted, and severely maladapted) were identified based on the RVESRI to RV systolic pressure r

89 enchmark methods, show that our SCCA methods identify better or similar correlation coefficients, and

90 s and multiple learning tests from 1486 rats identified BRaf as the key missing signaling effector in

91 We identified BRPF1 deletions or point mutations in six add

92 These motifs are challenging to identify, but once found they can point to larger networ

93 mplified upon anti-PD-1 therapy and could be identified by a sustained coexpression of PD-1 and TIGIT

94 Birthing of cubs in January was identified by a transient increase in HR and activity.

95 non-canonical miRNA-binding sites from peaks identified by Ago2 Cross-Linked ImmunoPrecipitation asso

96 Mitral annular calcium (MAC), commonly identified by cardiac imaging, is associated with cardio

97 The candidates are first identified by focusing on structures with methane-inacce

98 nificance of mutations in the CTLA-4 pathway identified by gene-sequencing approaches.

99 uct, 3-quinolinecarboxylic acid (3-QCA), was identified by liquid chromatography high resolution tand

100 C. africana was rapidly and reliably identified by microscopical and molecular analysis.

101 e under the same experimental conditions and identified by molecular PCR assay based on the ITS-5.8S

102 To further characterize genes identified by our screen, we compared the functional con

103 Of 374 studies identified by our search, 30 were included in our study,

104 t a tumor suppressor function for KIND1, and identify c-Jun N-terminal kinase and NF-kappaB as potent

105 Here, we propose a new unbiased method to identify canonical and non-canonical miRNA-binding sites

106 Collectively, these findings identify CD4(+) T cell subsets with properties critical

107 powerful method for characterizing visually identified cells in intact neural circuits, but it requi

108 To identify common or rare genetic variation with potential

109 We identified compounds that match the pharmacophore of the

110 teins associated with drug responses further identified corresponding synergistic or antagonistic dru

111 Among the eight potential CyCs identified, CyC 17 exhibited the best extracellular anti

112 ssing, and storage of deuodenoscopes did not identify deviations from US Food and Drug Administration

113 ne of the most common brain malformations to identify differences in the effect of virtual corpus cal

114 Identifying differentially expressed (DE) genes from RNA

115 However, identifying distinct responses will enable novel routes

116 le as interdependent coupled oscillators and identify DNA replication as a critical process in the ci

117 photo-oxidized heterocyclic rings, have been identified during photodegradation of SDs, whereas a new

118 We further functionally identified EgWRI1-1, one of three EgWRI1 orthologs, by g

119 quantitative methodologies and suitable for identifying exposure to unknown organophosphorus agents.

120 Interaction assays identified FDH as a potential substrate for the RING-typ

121 We identify five factors, including the HIV co-receptors CD

122 By pharmacologic and genetic studies, we identify FKBP12 as a novel hepcidin regulator.

123 No probe was identified for AST levels.

124 a PCSK9 variant (rs11206510), which has been identified for early onset myocardial infarction (MI), m

125 w, emerging opportunities and challenges are identified for MOF-enabled device functionality and tech

126 ween January 3, 2006, and May 30, 2012, were identified from electronic medical records (n = 830).

127 Target genes of a cis-regulatory motif were identified from the network via the motif's enrichment o

128 a technique called 'sieve analysis', one can identify functional specificities of vaccine-induced imm

129 Our data identify Gag-protease as a major determinant of subtype

130 neuroblastoma metastasis in vivo Overall, we identify gene expression signatures and candidate therap

131 Whole-exome sequencing was performed to identify gene variants.

132 We aimed to identify genetic and pathological markers that have the

133 ortant emerging application of Tn-Seq is for identifying genetic interactions, which involves compari

134 osome maturation." In this issue, Yin et al. identify GOP-1 as essential for the maturation of phagos

135 We thus identify Gpr124 as an endothelial GPCR specifically requ

136 pulation sample drawn from the UK Biobank to identify healthy-weight-sustaining density environments.

137 inhibitors of the CXCL1-CXCR2 signaling axis identified HIF-2alpha-dependent neutrophil recruitment a

138 ical, serological, and imaging biomarkers to identify high-risk patients, and clinical trials evaluat

139 finity purification method that unexpectedly identifies hundreds of ribosome-associated proteins (RAP

140 The participants identified important limitations and gaps in scientific

141 y published qualitative research was used to identify important domains for the Population, Intervent

142 Nonsentinel-node metastases, identified in 11.5% of the patients in the dissection gr

143 Emphysema was identified in 38% of patients.

144 murine allele by inserting a point mutation identified in a patient with NSCL/P.

145 we show that an rpsA polymorphism previously identified in a PZA resistant strain does not confer PZA

146 teristics and survival of patients with ACOS identified in a real-life cohort of patients with COPD.

147 occupancy by N-glycans are all detected and identified in a single experimental procedure.

148 k factors and potentially pathogenic alleles identified in future studies.

149 MERS-CoV was first identified in June 2012 and has since spread in humans a

150 ibit the same nitrogen isotopic ratio offset identified in modern corals.

151 Fourty-eight bioactive compounds were identified in Saskatoon berry genotypes, including twent

152 nt years, enhancers have been systematically identified in such projects as FANTOM and ENCODE, formin

153 Thirteen independent risk factors were identified in the derivation cohort and were combined in

154 differentially expressed miRNAs (DEMs) were identified in the entire TAA-treatment course.

155 nfectants-to benzyldimethyl amine (BDMA) was identified in the genome of Pseudomonas sp. BIOMIG1, whi

156 disorders, we investigated missense variants identified in the intracellular C-terminal domain of the

157 Forty of 53 patients (75%) identified in the literature review who underwent total-

158 Extracellular DNA (eDNA) has been identified in the matrix of many different monospecies b

159 ily Molybdate Transporter type 1 (MOT1) were identified in the model legume Medicago truncatula and t

160 8(+) T cells and CD8(+) dendritic cells were identified in the tumor microenvironment.

161 To identify incidence of and risk factors for calcification

162 A total of 41 different SERAC1 variants were identified, including 20 that have not been reported bef

163 ficant signals that have not been previously identified, including 9 low-frequency variants pointing

164 V antivirals, and is an exciting prospect to identify inhibitors for the many other viral pathogens o

165 e transgenerational asthma model was used to identify involved pathways.

166 sing global reasoning on the RN causality to identify key-nodes.

167 to food fraud problems, with an objective of identifying key markers that could be investigated furth

168 for certain enzymes, HTS assays designed to identify ligands that block protein binding are much mor

169 We identified low but escalating risk of severe M. chimaera

170 condition, it is of particular importance to identify malnourished patients so that nutritional thera

171 Collectively, these results identify mechanisms through which FGF signaling regulate

172 Additionally, we aimed to identify microbial patterns associated with the onset of

173 cardiovascular disease and healthy controls, identifying microbial strains and functions associated w

174 The aim of the present study is to identify microbiota surrounding exposed dental implants

175 Thus, our study identifies miR-146a as an important molecular brake that

176 ed genes (DEGs), but analysis of KC cultures identified more PP- and PN-decreased DEGs.

177 screen of small molecule compound libraries identified more than thirty hits that increased MBNL1 ex

178 The screen identified multiple candidates in many cell signaling pa

179 ces in genome sequencing make it possible to identify multiple disease-related mutations, but there i

180 By identifying Nck as an important driver of breast carcino

181 ty in biological networks, it is possible to identify network motifs that lead to functional outputs

182 To identify neural activity specifically associated with co

183 Computational modeling can aid in identifying neural generators of field potentials.

184 Targeted metabolomics methods have already identified new molecular markers and metabolomic signatu

185 velop new hypotheses for disease mechanisms, identify new disease biomarkers, and reposition drugs fo

186 In this study, we identify new functional roles of RASSF4.

187 nditions and provides a simple framework for identifying new conditions that tolerate challenging fun

188 We set out to identify novel and functionally important endothelial ln

189 partners that bind to mutated EGFR can help identify novel targets for drug discovery.

190 erstanding of pathogenic pathways in AKI may identify novel therapeutic approaches.

191 Population-based studies have identified numerous factors that modify the atrial subst

192 Two highly significant CAD loci were identified on chromosome 17q21.2 (NPL score of 6.20) and

193 ionally, we performed a genome-wide scan and identified one SNP with significantly different frequenc

194 Instead, we have identified other features of PKA signaling for reducing

195 Unexpectedly, we identified PABPN1-dependent ALYREF binding near the 3' e

196 We identified pathogenic mutations in 36 of 204 (17.6%) pat

197 Using multiple labeling approaches to identify pathways and their postsynaptic sites in the am

198 probability that individual tests correctly identified patients with sarcoidosis.

199 Vmax >/=5 m/s at the time of AS diagnosis identifies patients with very severe AS at high risk of

200 nuous flow-LVAD database (n=354) was used to identify patients with chest computed tomographies perfo

201 use of the SOFA and qSOFA classifications to identify patients with infection who are at elevated ris

202 We then used cluster analysis to identify patterns of individual differences in compulsiv

203 ) are limited by a poor predictive value for identifying people at the highest risk for progressing t

204 reatment advancements, but also for possibly identifying peripheral biomarkers that will eliminate th

205 robust to platform/batch effects and able to identify perturbed pathways in individual samples.

206 RNA-seq and RT-qPCR identified potential downstream genes of SPL4.

207 To identify potential fine differences between rHBeAg and H

208 ion of central metabolic pathways, which may identify potential therapeutic targets for the disease.

209 We used genomic sequencing to identify potentially pathogenic gene variants in familie

210 ce of resistance mechanisms with the need to identify predictive factors of therapy response.

211 chical logistic regression model was used to identify predictors of delayed fixation.

212 For fluorene, such signature is not identified probably due to lower oscillator strength of

213 Our results identify promoter shape as a molecular trait that can ev

214 These newly identified promoters are shown to be transcriptionally a

215 Further, we identify promoters able to drive strong expression in mu

216 We find that more than half the identified proteins possess multiple sites of phosphoryl

217 ave become the state-of-the-art procedure to identify quantitative trait nucleotides (QTNs) associate

218 fundamental integrative operation, but also identify quantitatively the multisensory transform used

219 y screen for homozygous deletions, aiming to identify rare tumour suppressors.

220 included in the review (from a total of 1281 identified records) show that the behavioral phenotype o

221 sitivity of 75% and a specificity of 100% in identifying recurrent or persistent EMPD.

222 Six latent classes were identified, representing subphenotypes of AD, with remar

223 Two notable common variants were identified: rs10791286, an intronic variant in OPCML (P=

224 he basis of putative biological function and identified rs34481144 in the 5' UTR.

225 at a single marker, Neuromedin B mRNA (Nmb), identifies RTN neurons in rodents.

226 We probed these interactions genetically and identified second-site suppressors of lethal mutations i

227 Together, these findings identify Sema3E as a novel regulatory molecule in allerg

228 From these, the secondary chemical screen identified SETD8, the H4(K20me1) methyltransferase, as a

229 Here, we identified seven unrelated individuals affected with an

230 In particular, we identified several arginine residues that interact with

231 cis and -trans regulators of EIF2B5 splicing identified several factors that influence intron retenti

232 croarray based transcriptional profiling and identified several novel candidate retinotectal guidance

233 cytometry by time-of-flight, we were able to identify several major time-dependent phenotypic changes

234 Data visualisation and statistical analysis identified significant chemical changes in pet food as a

235 We identified significant group differences in striatal dop

236 nvolve the stages of polymerase activity and identify significant changes in activity between experim

237 ethods and techniques for scaffold assembly, identifying similarities and dissimilarities across asse

238 This work identifies simple synthetic parameters, such as stirring

239 We identified single-point mutations in the Fc domain (e.g.

240 Among others, we identified sites catalyzed at faster rates with potentia

241 Kee et al. (2017) and Kirkeby et al. (2017) identify specific markers of midbrain dopaminergic proge

242 ene set enrichment and leading edge analyses identified Sphingosine kinase 1 (Sphk1) in the highest n

243 Similar procedures can be applied to identify sulfated proteins in yeast and human proteome m

244 ependent processing was useful in helping to identify target odors over background.

245 that would predict response to radiation and identify target pathways that may be exploited for neoad

246 between places and services could be key to identifying targets for interventions to reverse this tr

247 nisms of coding and noncoding alteration and identify ten recurrently altered pathways, with associat

248 In addition, avenues are identified that may be exploited for photosynthesis engi

249 the characteristics of the study population identified that the Sokal risk score and duration of IM

250 We identified the following variables as unfavourable predi

251 Imaging techniques have identified the presence of bursitis in more than half of

252 Affinity chromatography experiments identified the primary target of the compounds as the T3

253 a high-throughput and efficient strategy to identify the E3-substrate interaction.

254 To identify the endogenous receptor for PGE2-G, we performe

255 jective optimization model to systematically identify the environmentally optimal use of biomass for

256 age choices made by multipotent cells and to identify the genes influencing these decisions is challe

257 Using ex vivo and in vivo models, we identify the Hedgehog (HH) paracrine system as a candida

258 as well as in the public sector, could help identify the majority of missing cases.

259 follow-up of patients with TTP is crucial to identify the occurrence of other autoimmune diseases, to

260 plication of response surface methodology to identify the optimal Pd-Bi-Te catalyst stoichiometry.

261 re of radiation sensitivity could be used to identify the optimum radiotherapy dose.

262 has a six-bladed beta-propeller fold, and we identify the region that interacts with PfRh5.

263 The aim of this study was to identify the residues of WRN involved in the binding and

264 We aimed to identify the role of the enzyme acid sphingomyelinase in

265 ID (Saccharomyces cerevisiae IDentifier), to identify the strains present in complex environmental sa

266 onal anti-M1 antibodies, which then serve to identify the universal biomarker for the influenza virus

267 carrier state in stallions by unequivocally identifying the ampullae as the primary sites of viral p

268 Thus identifying the epigenetic activator of ERalpha that can

269 By identifying the residues that establish plaque stability

270 Identifying the substrates of an E3 holds the key to elu

271 Despite no novel chemical marker has been identified, the (1)H NMR chemometrics approach may contr

272 PRC1-Br140 and PRC1-Fs(1)h interactions and identify their genomic binding sites.

273 However, objective methods for identifying these ICU patient subgroups are lacking.

274 RVA profile was the easiest way of identifying this characteristic as potentially problemat

275 o monitor responses to treatment, to quickly identify those therapies that are ineffective, modify or

276 seek to develop and demonstrate a method for identifying those mixtures that are most prevalent in hu

277 Herein, we exhibit that CD26 identifies three T helper subsets with distinct immunolo

278 Here, we identify TIAM1 as a critical antagonist of CRC progressi

279 Collectively, our findings identified TNC as a pivotal initiator of elevated NOTCH

280 nse and four missense Gmsacpd-c mutants were identified to have high levels of seed, nodule, and leaf

281 n the PREs are cognate binding sites for the identified transcription factors and are necessary and s

282 ensive mutagenesis approach with the goal of identifying trimer variants with improved antigenic and

283 Here we identify twenty-six DHC-derived features that provide bi

284 Three genes were identified, two possibly involved in biogenesis of the m

285 iexcitons, are possible but are difficult to identify unambiguously using linear optical spectroscopy

286 CAPTURE (COPD Assessment in Primary Care to Identify Undiagnosed Respiratory Disease and Exacerbatio

287 tical factors involved in invasion have been identified using biochemical and genetic approaches incl

288 Cases were identified using glaucoma surgical codes for trabeculect

289 r and 2) hyperactivity throughout childhood, identified using latent class growth modeling.

290 rmed HPV-negative OPSCC in 2010 to 2012 were identified using the National Cancer Data Base, which in

291 20 of 41 participants, panel genetic testing identified variants classified as pathogenic, likely pat

292 Spectral-domain OCT is useful in identifying various imaging findings in DME.

293 to map different global climate regimes and identify where coarse climate data is most and least lik

294 atch criteria were analyzed as a subgroup to identify whether they had different treatment responses

295 A number of initiatives were identified which can be used to support older patients (

296 Alzheimer's disease (AD; n = 164) was identified with 70% sensitivity and specificity, which a

297 All variants were identified with massive parallel sequencing and confirme

298 mometabolic, and hypometabolic patients were identified with the use of Boothby's standard.

299 raphs obtained from diabetic patients and to identify, with high reliability, which cases should be r

300 Additional illnesses were identified within several days.