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5 show that an antibody, recognizing a public idiotope associated with anti-HIV-1 antibodies can funct
6 bind, through the GD3 binding site, to a VH idiotope (designated IdHOM) on solid phase anti-GD3 mAb.
8 et of CSF oligoclonal bands, the presence of idiotope (Id)-bearing antibodies sharing an Id with a mu
9 red for the GD3 binding pocket, but that the idiotope is necessary for homophilic binding, which is r
10 turally defined IdHOM and conclude that this idiotope is not required for the GD3 binding pocket, but
14 ain VH genes may result in the expression of idiotopes that allow homophilic binding, and this may re
15 and 2) those residues that contribute to the idiotopes that are potential targets of patients' immune
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