ライフサイエンスコーパス: ignorance

1 to tolerance but is because of immunologic 'ignorance'.

2 ncluding clonal deletion, anergy, and clonal ignorance.

3 cells and contribute to the origin of clonal ignorance.

4 rmally induce B cell anergy or B cell clonal ignorance.

5 ne attack through immune system exclusion or ignorance.

6 earance is not attributable to immunological ignorance.

7 ve T cells, creating a state of tolerance or ignorance.

8 seless destruction who thrive in poverty and ignorance.

9 mes to imagine the breathtaking scope of our ignorance.

10 tolerance in B cells, a state termed clonal ignorance.

11 tional inactivation because of immunological ignorance.

12 cific for the Sm that remain tolerant due to ignorance.

13 f B cells and not as a result of true clonal ignorance.

14 gen-dependent activation to preserve clonal "ignorance."

15 ith communication in therapy, and widespread ignorance about how to obtain services.

16 ianism that continues to incubate stigma and ignorance about mental illness.

17 Degree of ignorance about surgery, symptoms impeding work, and a m

18 oblems in aDNA studies are contamination and ignorance about taphonomy (transportation, incorporation

19 y used in protein biophysics even though our ignorance about the HX mechanism makes data interpretati

20 e factor uncertainties are most sensitive to ignorance about water-oil ratio (WOR) and steam-oil rati

21 l, GITR stimulation overcomes self-tolerance/ignorance and enhances T cell-mediated antitumor activit

22 LA I knockdown hESC(siRNA+IB) provoke T-cell ignorance and experience largely mitigated xenogeneic re

23 istory of epilepsy has been characterized by ignorance and human suffering.

24 ation which is not due to immune deletion or ignorance and is associated with early development of a

25 Barriers include ignorance and lack of time and money.

26 individuals for their efforts to overcome my ignorance and set me on the straight and narrow path to

27 hese findings question the concept of clonal ignorance and show that physiological concentrations of

28 and the understanding of tumor immunological ignorance and support intratumoral vaccination as a stra

29 ce have been classified as deletion, anergy, ignorance and suppression/regulation.

30 or differentiation antigens can break immune ignorance and tolerance to self and induce protective tu

31 eness (clonal exhaustion-deletion and immune ignorance) and their regulation removed much of the hist

32 iated by clonal deletion, (ii) T-cell clonal ignorance, and (iii) nondeletional T-cell tolerance medi

33 h afflicted with a remarkable degree of self-ignorance, are able to realize their values in their liv

34 male antigen HY, we evaluated whether tumor ignorance as determined by lack of a systemic immune res

35 The continued cost of ignorance borne by countries without civil registration

36 Breaking CTL ignorance by immunization with a tumor antigen-derived p

37 This process of "learned ignorance" could allow autoreactive B cells access to th

38 no information about outcome probabilities (ignorance cue).

39 vated when ambiguous cues were compared with ignorance cues.

40 Political ignorance, denial and obduracy (as with HIV/AIDS) furthe

41 tion leading to anergy for naive T cells and ignorance for memory T cells.

42 creasingly produce verbal acknowledgments of ignorance ("I don't know").

43 suggesting that they recognize knowledge and ignorance in others.

44 d are often described as the consequences of ignorance, irrationality or specific biases.

45 Our relative ignorance is largely due to the lack of technologies wit

46 Our ignorance is most acute for segregating variation within

47 to a CTL response and that a similar type of ignorance may explain why HPV-associated cervical cancer

48 results suggest a novel mechanism for T cell ignorance of agonist MHC-peptide complexes based on domi

49 mous with contraception, helping to maintain ignorance of alternative methods.

50 numerous infectious and metabolic diseases, ignorance of amyloid structure has hindered similar appr

51 i-LFA-1 therapy was not simply due to clonal ignorance of donor Ags in that the majority of recipient

52 tary immunisation, and most caregivers cited ignorance of either vaccine importance or availability a

53 and use it to examine the effect of manager ignorance of household decisions on resource management

54 Ignorance of how Ins(3,4,5,6)P(4) is synthesized has lon

55 t further understanding has been hindered by ignorance of how it is made in cells.

56 Systemic tumor ignorance of MB49 was demonstrated by the lack of a sple

57 tended to avoid nutritional problems, plead ignorance of nutrition principles, and delegate the nutr

58 dedicated field research has brought us from ignorance of our closest relatives to the discovery that

59 The development of therapies is hindered by ignorance of potential beneficiary patient subgroups.

60 cer and autoimmune disease is limited by our ignorance of relevant self-peptide target antigens.

61 signals partially overcame memory CD8 T-cell ignorance of self-antigen.

62 ufficient separation of glycemic levels, and ignorance of smoking history as a possible confounder.

63 l rise to ocean warming (notwithstanding our ignorance of the abyssal and Southern Oceans): the histo

64 So ignorance of the brain should not prohibit development o

65 ter in diabetic ketoacidosis underscored our ignorance of the controls in human fuel metabolism.

66 The pronounced degree of T cell ignorance of the fetus also has implications for the pat

67 is molecular fossil record is constrained by ignorance of the function of their molecular antecedents

68 ly stages of the epidemic, assuming complete ignorance of the future environmental drivers, fail beca

69 Ignorance of the impact of changes in soil properties, C

70 in the nasopharynx is to maintain tolerance/ignorance of the large volume of harmless antigens and b

71 al was justified by "... our almost complete ignorance of the mechanism for the unfolding of the gene

72 t lignocellulosic biomass is hampered by our ignorance of the molecular basis for its properties such

73 cribe the current state of our knowledge and ignorance of the molecular mechanics underlying eukaryot

74 iotic multiresistant bacteria is hampered by ignorance of the natural history of resistance genes, th

75 This program is challenged by our ignorance of the physiological and ecological features m

76 s have often been attributed to disease, but ignorance of the relative importance and mode of action

77 on of this modification has been hindered by ignorance of the responsible methyltransferase.

78 far removed from its natural habitats and in ignorance of the selective pressures that have shaped it

79 and its function fully have been hampered by ignorance of the structural details of its interactions

80 the field has been significantly hampered by ignorance of the underlying intracellular pathways.

81 Ignorance of these pitfalls directly affects the quality

82 Furthermore, we demonstrate that the ignorance of truncated genes in the estimation does not

83 l clonal deletion or inactivation to clonal "ignorance" of the peripheral transgene-encoded Ag.

84 immunogenic tumors result in either complete ignorance or tolerance induction, suggesting inadequate

85 nt; thus, it must maintain a state of immune ignorance or tolerance not to overrespond to harmless en

86 ly basis and must maintain a state of immune ignorance or tolerance to these harmless stimuli to reta

87 to recognize the antigen (i.e. immunological ignorance) or to an active induction of an antigen-speci

88 T cell tolerance in vivo, such as deletion, ignorance, or immunosuppression.

89 nded normally to i.p. challenge, implicating ignorance rather than anergy as the main reason for the

90 We provide evidence that immunological ignorance, rather than anergy or deletion, of tumor anti

91 To reverse the state of ignorance regarding human beta-cell signaling, we sugges

92 Despite our ignorance regarding the mechanism of angina relief, clin

93 ved remain elusive, in large part because of ignorance regarding the numbers of proteins in regulator

94 However, in contrast to ignorance, results presented herein demonstrate that int

95 but politics, prejudice, and our continuing ignorance still impede optimum prescribing.

96 Instead, they remain at a stage of "clonal ignorance"; that is, they do not proliferate and differe

97 ified (clonal exhaustion-deletion and immune ignorance) that linked organ engraftment and the acquire

98 f the degree of our current immunobiological ignorance, the availability of powerful new tools for di

99 Thus, instead of immune ignorance, these studies demonstrate the activation of a

100 of peripheral tissues is not attributable to ignorance, timing-based tolerance, or special circulatio

101 arenchyma contributes to the systemic immune ignorance to Ags localized exclusively within the brain.

102 uld counteract the intrinsic systemic immune ignorance to Ags localized exclusively within the brain.

103 nd the start of a journey from psychological ignorance to enlightenment.

104 a differentiation scheme in which peripheral ignorance to Sm is maintained in mice by the differentia

105 ed stromal cells may overcome immunological "ignorance" to solid tumors.

106 ng must maintain a high threshold of immune 'ignorance' to innocuous antigens to avoid inflammatory d

107 clonal deletion and are examples of "clonal ignorance." To understand the genetic origin of Abs from

108 sult in the distinct immunological states of ignorance, tolerance or immunity.

109 They look toward an available adult, convey ignorance via nonverbal gestures (flips/shrugs), and inc

110 k, where outcome probabilities are known, or ignorance, where outcomes are completely unknown and unk

111 As a consequence of bias and ignorance within the medical profession, lesbians and ga