ライフサイエンスコーパス: illicit

1 le tissue is a valid marker for detection of illicit 17beta oestradiol and/or dexamethasone use in be

2 identification of links between seizures of illicit 3,4-methylenedioxymethamphetamine (MDMA or "ecst

3 es in Xenopus oocytes, both Ca(2+) and Na(+) illicit 5-HT-induced currents in the Asn-101 mutants and

4 which can be used as potential biomarkers of illicit 5-nitroimidazole abuse.

5 the ability of extracellular testosterone to illicit a rapid, non-genomic signaling response in HEK-2

6 Single-RNA injections were able to illicit a robust induction of SMN protein in the brain a

7 sist in the identification and evaluation of illicit activities and provide information that would he

8 Illicit anabolic-androgenic steroid (AAS) abuse, though

9 Millions of individuals have used illicit anabolic-androgenic steroids (AAS), but the long

10 oral interventions in reducing self-reported illicit and pharmaceutical drug use among adolescents.

11 Substance use disorders involving illicit and prescription drugs are a serious public heal

12 For problem use of illicit and prescription drugs, sensitivity ranged from

13 The abuse of opioid drugs, both illicit and prescription, is a persistent problem in the

14 racies in histories, and determining how the illicit beverage was shared.

15 erations in its signaling have been shown to illicit biphasic effects on tumor progression and metast

16 There is a shift in the production of illicit cannabis plant material from regular marijuana t

17 Overall, the potency of illicit cannabis plant material has consistently increas

18 xamines the concentration of cannabinoids in illicit cannabis products seized by the U.S. Drug Enforc

19 Over the last 25 years, illicit cannabis use and cannabis use disorders have inc

20 have contributed to increased prevalence of illicit cannabis use and cannabis use disorders.

21 In the earlier period, illicit cannabis use and disorders decreased similarly i

22 Past-year illicit cannabis use and DSM-IV cannabis use disorder.

23 Overall, from 1991-1992 to 2012-2013, illicit cannabis use increased significantly more in sta

24 Little is known about MML and adult illicit cannabis use or cannabis use disorders considere

25 d price policies are undermined by licit and illicit cheap supplies.

26 statistical analyses can be used to classify illicit cocaine as originating from one of 19 growing re

27 Most of the illicit cocaine consumed in the United States and elsewh

28 entify the types of sewage overflows and the illicit connection status of drainage systems.

29 .6%), with nonmedical routes of exposure and illicit contributory drugs particularly prevalent among

30 r to single-stranded telomere DNA to prevent illicit DNA damage responses and to enhance telomerase-m

31 ukaryotic chromosome ends are protected from illicit DNA joining by protein-DNA complexes called telo

32 substance use disorders, such as alcohol and illicit drug abuse or dependence.

33 hypertension, liver disease, renal disease, illicit drug abuse, and poor performance status, but low

34 ne dependence; alcohol abuse/dependence; and illicit drug abuse/dependence.

35 ral drug residues, including the potentially illicit drug amphetamine, at 6 stream sites along an urb

36 ysical processes on the transformation of 30 illicit drug and pharmaceutical residues were quantified

37 y metabolic processes) and transformation of illicit drug biomarkers (secondary metabolic processes)

38 es most health burden in eastern Europe, and illicit drug burden is higher in the USA, Canada, Austra

39 nfectious and noninfectious complications of illicit drug can expedite diagnosis and medical treatmen

40 Synthetic cannabinoids are an emerging illicit drug class.

41 genetic factors-one predisposing largely to illicit drug dependence, the other primarily to licit dr

42 control groups for genetic investigations of illicit drug dependence.

43 endence, including extension of liability to illicit drug dependence.

44 g that liability likely extends to nonopioid illicit drug dependence.

45 to identify CAS of forensic significance for illicit drug detection, profiling, and attribution.

46 parkinsonian syndromes and in some cases of illicit drug exposure.

47 e also used for direct quantification of the illicit drug fentanyl in red blood cell extracts.

48 tory model, which also fit well, contained 1 illicit drug genetic factor--loading only on cannabis an

49 Cannabis is the most widely used illicit drug globally, and users are at increased risk o

50 field can provide an unbiased look into the illicit drug habits of large populations as well as spec

51 Marijuana is the most widely used illicit drug in the United States and all over the world

52 Marijuana is the most commonly used illicit drug in the United States, but little is known a

53 phetamine is the second most frequently used illicit drug in the United States.

54 Cannabis is the most widely used illicit drug in the world, and patients seeking treatmen

55 Cannabis is the most widely used illicit drug in the world.

56 ned the relation between time since onset of illicit drug injection (time at risk) and rates of hepat

57 Marijuana is a widely abused illicit drug known to cause significant cognitive impair

58 rdless of the type of normalization as daily illicit drug loads appeared to vary substantially more t

59 opulation is negligible compared to those of illicit drug loads.

60 The illicit drug methylamphetamine is often prepared from th

61 ns with tissue volume reduction, and alcohol/illicit drug misuse had no significant associations when

62 ehavioral interventions to prevent or reduce illicit drug or nonmedical pharmaceutical use in childre

63 ogical, nuclear, and explosive materials and illicit drug precursors can be rapidly detected and iden

64 Attribution of the origin of an illicit drug relies on identification of compounds indic

65 As part of the Illicit Drug Reporting System study, PWIDs reported syri

66 anding field that can provide information on illicit drug usage in communities, based on the measured

67 ng (adjusted OR 1.74, 95% CI 1.08-2.81), any illicit drug use (1.72, 1.07-2.79) and weekly cannabis u

68 on (6.1% vs. 3.7% males, Z=2.58, p<0.05) and illicit drug use (3.3% vs. 0.6% males with drug abuse, Z

69 0 [15%]), excessive drinking (34 [26%]), and illicit drug use (38 [29%]).

70 ratio 4.81; 95% CI 2.03-11.36, p=0.0005) and illicit drug use (4.75; 1.19-18.96, p=0.026) were signif

71 ntiretroviral therapies (63%-79%) and active illicit drug use (53%-55%).

72 dence (beta = -0.27, P = 0.58) and long-term illicit drug use (beta = -0.04, P = 0.87) tended to be n

73 Intravenous illicit drug use (IDU) and hepatitis C infection (HCV) c

74 y associated with chronic HCV infection were illicit drug use (including injection drugs) and receipt

75 association between longitudinal patterns of illicit drug use and clinical progression of human immun

76 was observed between ever (past or current) illicit drug use and cognitive functioning (beta = 0.62,

77 stigated the prospective association between illicit drug use and cognitive functioning during the mi

78 vels of miRNA-34a correlated positively with illicit drug use and ethanol consumption.

79 l computer-based interviews, which addressed illicit drug use and other factors, were completed by HI

80 do not support widespread implementation of illicit drug use and prescription drug misuse screening

81 ally in screening and brief intervention for illicit drug use and prescription drug misuse, based in

82 Furthermore, we show differential effects of illicit drug use and prolonged freezing on SE-mediated H

83 tly accounted for 35% of the heritability in illicit drug use and, when combined with common variants

84 Illicit drug use at 42 years of age was based on self-re

85 bsequent initiation of tobacco, alcohol, and illicit drug use by 14 years of age and onset of substan

86 Illicit drug use can result in a wide range of medical c

87 e potential effects of alcohol, tobacco, and illicit drug use during this period on: social, psycholo

88 ated the accuracy of the "gateway sequence" (illicit drug use following licit drugs) for predicting a

89 Illicit drug use has a global concern and effective moni

90 matic drinking behavior, but their effect on illicit drug use has yet to be evaluated.

91 Illicit drug use in the past year was higher in the SELC

92 Per capita illicit drug use increased significantly during the moni

93 ation level, it does not appear that current illicit drug use is associated with impaired cognitive f

94 Alcohol and illicit drug use is highly associated with the abuse of

95 o estimate the association between different illicit drug use measures at 42 years of age and cogniti

96 of ADHD significantly predicted tobacco and illicit drug use only (adjusted odds ratios, 2.01 and 2.

97 ncentration, intensity/size) irrespective of illicit drug use or duration of semen freezing.

98 lements may be needed for patients reporting illicit drug use or who have unmet needs.

99 n on the onset, prevalence, and frequency of illicit drug use over a 2-year period.

100 ous diseases specialists-to complications of illicit drug use that may be underrecognized.

101 ression to 1.92 (1.79-2.04) for anxiety; for illicit drug use they ranged from 1.36 (1.25-1.49) for a

102 immediate withdrawal symptoms and replacing illicit drug use with long-acting opiate drugs.

103 substance use (smoking, binge drinking, and illicit drug use), and (3) domestic violence (emotional

104 ntal health problems, daily tobacco smoking, illicit drug use, and dependence were all more common in

105 dictors of USA300 included HIV, younger age, illicit drug use, and male sex; all but 1 colonized indi

106 isk behaviors including smoking, alcohol and illicit drug use, and sexual risk-taking.

107 models that adjusted for time-variant (other illicit drug use, antipsychotic medication adherence) an

108 ous variants may be important in etiology of illicit drug use, but detection of individual variants w

109 t assessment of medical history, alcohol and illicit drug use, HCV RNA levels, hepatitis B virus surf

110 with an HBV or HCV patient, >1 sex partner, illicit drug use, or incarceration (21% of cases versus

111 enied a history of contact with sick people, illicit drug use, or recent travel.

112 ast 30 years, cigarette smoking, alcohol and illicit drug use, sexual activity, and violent behavior

113 use disorders and any substance use, except illicit drug use, than nonpregnant women.

114 g individuals with HIV who have a history of illicit drug use, those coinfected with hepatitis C viru

115 replicated specific genetic contributions to illicit drug use, though it is clear that there is a str

116 ng, physical inactivity, unhealthy diet, and illicit drug use-according to CHC after adjusting for so

117 stolic BP relation was partially mediated by illicit drug use.

118 is low and associated with being UK born or illicit drug use.

119 e lower in patients reporting unmet needs or illicit drug use.

120 rs (HAND), which is typically exacerbated by illicit drug use.

121 mmonly encountered adverse ocular effects of illicit drug use.

122 uld acknowledge high rates of depression and illicit drug use.

123 outcomes included hazardous alcohol use and illicit drug use.

124 cigarette smoking, alcohol consumption, and illicit drug use.

125 lts were stratified by unhealthy alcohol and illicit drug use.

126 thy alcohol use and 28.4% reported past-year illicit drug use.

127 MDMA (Ecstasy) is an illicit drug used by young adults at hot, crowed "rave"

128 Importance: Methamphetamine is a common illicit drug used worldwide.

129 ), self-reported alcohol drinkers (77%), and illicit drug users (90%).

130 mmunity-recruited cohort of HIV-seropositive illicit drug users during a community-wide ART expansion

131 espite cannabis being the most commonly used illicit drug worldwide, a MALDI-MS method for the detect

132 As the most widely used illicit drug worldwide, and as a source of numerous unde

133 Cannabis is the most commonly used illicit drug worldwide, and use is typically initiated d

134 Use of Cannabis, the most widely used illicit drug worldwide, is associated with acute anxiety

135 Cannabis is the most commonly used illicit drug worldwide.

136 though marijuana is the most commonly abused illicit drug, the implications of legalized, widespread,

137 n of association was observed when comparing illicit drug-dependent (n = 191) and nondependent (n = 3

138 he U.S.A., cocaine is the second most abused illicit drug.

139 Cannabis is the world's most commonly used illicit drug.

140 [34.7%]) and recent use of cocaine or other illicit drugs (39 [13.5%]) were the most common causes o

141 dependence (17.95, 9.44-34.12), use of other illicit drugs (7.80, 4.46-13.63), and suicide attempt (6

142 se in young people for tobacco, alcohol, and illicit drugs (eg, cannabis, opioids, amphetamines, or c

143 ine aura (seven patients) and consumption of illicit drugs (five, no hallucinogens) were rare.

144 A), benzylamines (mono-, di-, and tri-), and illicit drugs (MA, MDEA, and haloperidol).

145 edients in pharmaceutical drug formulations, illicit drugs (methamphetamine, cocaine, and diacetylmor

146 up of neighborhood controls not dependent on illicit drugs (n = 340), 3 SNPs were significantly assoc

147 its effect among HIV-positive people who use illicit drugs (PWUD) has yet to be evaluated.

148 DR patterns and impacts among people who use illicit drugs (PWUD).

149 In this study, select illicit drugs (six drugs and eight metabolites) were det

150 ng therapy (15% cannabinoids alone; 8% other illicit drugs +/- cannabinoids).

151 to impact consumption of pharmaceuticals and illicit drugs - a priori to an unknown extent.

152 toxic effects from medications, alcohol, or illicit drugs also result in dilated cardiomyopathy.

153 commercial linear ion trap using mixtures of illicit drugs and acylcarnitines.

154 pointments, and two studies on abstinence of illicit drugs and alcohol use to prevent the reoccurrenc

155 volatile chemical signatures associated with illicit drugs and explosives (high and low) has been des

156 o used to detect trace chemical compounds in illicit drugs and explosives, in which samples were obta

157 The detection and mapping of illicit drugs and metabolites in latent fingermarks woul

158 ned for the quantitative determination of 24 illicit drugs and metabolites in urban sewage samples.

159 There was no interference from 70 licit and illicit drugs and metabolites.

160 ovide dynamic population normalized loads of illicit drugs and pharmaceuticals during a known period

161 Interestingly, illicit drugs and prolonged freezing decreased the level

162 However, the effect of illicit drugs and prolonged freezing on SE bioactivity i

163 ity of the above methodology to identify new illicit drugs and/or metabolites in sewage samples is al

164 Some illicit drugs are associated with rare infections, which

165 abusing or dependent on tobacco, alcohol, or illicit drugs are less likely to be placed on the waitin

166 Using several illicit drugs as analytes, the work presented here descr

167 interest were abuse of alcohol, tobacco, or illicit drugs based on information from Centers for Medi

168 sthesiologists to know about the most common illicit drugs being used, to know their side effects and

169 ble from ION-1 for retrospective testing for illicit drugs by enzyme-linked immunosorbent assay.

170 ting per capita consumption of, for example, illicit drugs by means of wastewater analysis (sometimes

171 ange of use for various classes of licit and illicit drugs by monitoring Athens' wastewater from 2010

172 atives can prevent or reduce the damage that illicit drugs cause to the public good are rarely inform

173 ons in the United States exceeds that of all illicit drugs combined except marijuana and has grown co

174 genetic datasets for alcohol, nicotine, and illicit drugs contain the family of KCNN genes.

175 pants in the ION-1 trial, 23% (n = 196) used illicit drugs during therapy (15% cannabinoids alone; 8%

176 e availability, synthesis, and popularity of illicit drugs evolve over time, new syndromes associated

177 t colorimetric presumptive identification of illicit drugs for determining illegal possession of cont

178 nonuse, asymptomatic use, and problem use of illicit drugs for U.S. adults in the general household p

179 The removal efficiencies of illicit drugs from the two WWTPs ranged from 4% (norcoca

180 The environmental emission of illicit drugs from WWTP discharges was calculated to ran

181 mework of appetitive behavior, the view that illicit drugs hijack reward circuits by hyperactivating

182 racy was achieved for the direct analysis of illicit drugs in 4 muL of raw blood, serum, and whole ur

183 achieved in the analysis of therapeutic and illicit drugs in 5 muL samples.

184 procedure, to assess the harms of a range of illicit drugs in an evidence-based fashion.

185 The presence of pharmaceuticals, including illicit drugs in aquatic systems, is a topic of environm

186 oxins in soil samples, the identification of illicit drugs in human blood, and the quantitation of ac

187 ound to predict the concentrations of select illicit drugs in raw wastewater (r(2) = 0.20-0.79; p </=

188 The consumption rate of target illicit drugs in the communities served by the two WWTPs

189 are purchased as alternatives to traditional illicit drugs of abuse and are manufactured to circumven

190 ility, where they maintained abstinence from illicit drugs of abuse and received behavioral therapy f

191 However, it is unknown whether, akin to illicit drugs of abuse such as cocaine or heroin, the ad

192 for the spatially resolved quantification of illicit drugs on the surface of a fingerprint using time

193 omes (SE) from healthy donors who do not use illicit drugs potently inhibit HIV-1.

194 Effect sizes for psychosocial treatments for illicit drugs ranged from the low-moderate to high-moder

195 SELCoH sample, with cannabis and cocaine the illicit drugs reported most frequently in both samples.

196 amphetamine; MDA) times higher mass flows of illicit drugs than did the WWTP that served a smaller po

197 Spatially resolved quantification of illicit drugs using imaging mass spectrometry is possibl

198 The direct effect of HIV proteins and illicit drugs was investigated on oxidative stress, surv

199 ors associated with transition from licit to illicit drugs were not revealed.

200 yses for survival and relapse to alcohol and illicit drugs were performed.

201 personal care products, pharmaceuticals, and illicit drugs) in wastewater effluent.

202 (nicotine, caffeine, alcohol, cannabis, and illicit drugs) was obtained for 8586 twins who were regi

203 r (PPY) for substance use (tobacco, alcohol, illicit drugs), to 19 to 25 cases per 100 PPY for nonadh

204 nt presumptive colorimetric field-testing of illicit drugs, allowing for an objective and user-friend

205 n of chemical warfare agent (CWA) simulants, illicit drugs, and explosives is demonstrated at nanogra

206 (at room temperature), including pesticides, illicit drugs, and explosives, were selected to evaluate

207 smitters, phosphopeptides, oligonucleotides, illicit drugs, and pharmaceutical compounds are successf

208 , younger age, white race, history of use of illicit drugs, history of other drug use disorders, and

209 nalysis of a wide range of compounds such as illicit drugs, pharmaceuticals, and pesticides-such that

210 ty degree, cannabis dependence, use of other illicit drugs, suicide attempt, depression, and welfare

211 drugs were involved in more deaths than were illicit drugs.

212 the top-named drugs and for prescription and illicit drugs.

213 site multicompound quantitative screening of illicit drugs.

214 and the use/misuse of nicotine, alcohol, and illicit drugs.

215 he chemical analysis of sewage biomarkers of illicit drugs.

216 of explosives, chemical warfare agents, and illicit drugs.

217 lf-reported current or past use of any of 12 illicit drugs.

218 ders, and are the targets of therapeutic and illicit drugs.

219 e was associated with the use of tobacco and illicit drugs.

220 positive urine drug screen for prototypical illicit drugs.

221 ) and methamphetamine (MA) are widely abused illicit drugs.

222 acteremia and recent use of cocaine or other illicit drugs.

223 legal drugs promotes subsequent addiction to illicit drugs.

224 cco and alcohol usually preceding the use of illicit drugs.

225 s, such as sex workers and people who inject illicit drugs.

226 ith those who used cannabinoids and/or other illicit drugs.

227 dies have examined the ecological effects of illicit drugs.

228 tobacco use, but are not available to target illicit drugs.

229 ee release areas, and to be current users of illicit drugs.

230 d into the aquatic ecosystem corresponded to illicit drugs/controlled substances such as ketamine and

231 that many licit (e.g., tobacco products) and illicit (e.g., marijuana) drugs have noteworthy chemosen

232 shonest athletes aiming at an artificial and illicit enhancement of their endurance performance.

233 ated cues have been implicated as a cause of illicit heroin use during methadone maintenance treatmen

234 the synthetic method used for manufacture in illicit laboratories.

235 have frequently been introduced to licit and illicit markets and rapidly distributed via worldwide op

236 Illicit methamphetamine abuse represents a major problem

237 of a rogue nuclear attack or interception of illicit nuclear materials, timely forensic investigation

238 The substantial increase in prescription and illicit opioid abuse observed over the last 2 decades ha

239 norphine group reduced the number of days of illicit opioid use per week from 5.4 days (95% CI, 5.1-5

240 24-week open-label clinical trial, in which illicit opioid use was measured by weekly urinalysis.

241 n addiction treatment, reduced self-reported illicit opioid use, and decreased use of inpatient addic

242 reductions from baseline in the frequency of illicit opioid use, but there were no significant differ

243 The percentage of participants negative for illicit opioid use, retention, naltrexone ingestion, and

244 outcomes were the self-reported frequency of illicit opioid use, the percentage of opioid-negative ur

245 Self-reported days of illicit opioid use, urine testing for illicit opioids, h

246 urine results, abstinence, and time to first illicit opioid use.

247 th 95% CI, -4.9 to -1.5; P < .001) and other illicit opioids (mean difference, -2.7 with 95% CI, -4.6

248 ge of urine samples that tested negative for illicit opioids across weeks 1 through 16 of 40.4% (95%

249 ignificantly more urine samples negative for illicit opioids during weeks 1 through 16 (P = .04).

250 The percentage of urine samples negative for illicit opioids for weeks 1 through 16 and for weeks 17

251 significantly lower use of heroin and other illicit opioids in the extended-release naltrexone group

252 Fewer women treated with BMT used illicit opioids near delivery (risk ratio=0.44, 95% CI:

253 ays of illicit opioid use, urine testing for illicit opioids, human immunodeficiency virus (HIV) risk

254 nd number of days of use of heroin and other illicit opioids.

255 ks during which patients were abstinent from illicit opioids.

256 mber of consecutive weeks of abstinence from illicit opioids.

257 cription opioids is more common than that of illicit opioids: Recent data indicate that approximately

258 als are shifting towards approaches that can illicit osteoinductive properties.

259 nionic surfactant sodium decyl sulfate (SDS) illicited PFAA chain-length dependent impacts in two neg

260 tible with botulism after drinking pruno, an illicit, prison-brewed alcoholic beverage.

261 rone (MDPV) is a common constituent of these illicit products, and its structural similarities to the

262 o contribute to dependence on both licit and illicit psychoactive substances, we know little of how t

263 Exclusion criteria were the use of illicit psychotropic substances, mental confusion, hepat

264 into heterochromatin structures that prevent illicit recombination events that cause genomic instabil

265 faithfully binds telomeric ssDNA and avoids illicit RNA binding that could result in its depletion f

266 of how pICln prevents Sm oligomerization on illicit RNA substrates.

267 he Sm proteins are gathered while preventing illicit Sm assembly on non-snRNAs is unknown.

268 zole SCs which are currently the predominant illicit smoking mixtures on the drug market is performed

269 Illicit substance abuse is a major health concern in the

270 past or current history of cocaine or other illicit substance abuse.

271 data provides the first indication that this illicit substance can have major implications on renal f

272 antibodies to immunize subjects against the illicit substance rather than administering therapeutics

273 In young men aged 20-24 years, alcohol and illicit substance use are responsible for 14% of total h

274 (e.g., precocious sexual activity, bullying, illicit substance use).

275 y disorder, smoking and alcohol consumption, illicit substance use, ever having separated from a long

276 r trauma, PTSD, depression, and co-occurring illicit substance use.

277 en the treatment groups regarding most other illicit substance use.

278 short-term abstinence from heroin and other illicit substances and should be considered as a treatme

279 maintaining abstinence from heroin and other illicit substances in newly detoxified individuals.

280 population are used to derive daily loads of illicit substances that are indexed to population.

281 For patients who continue to use illicit substances while receiving end-of-life care, exp

282 mine (MA) is one of the most commonly abused illicit substances worldwide.

283 ould include an inquiry regarding the use of illicit substances, anabolic-androgenic steroids, herbal

284 ic medications, and no current dependence on illicit substances.

285 idely implemented tools for the detection of illicit substances.

286 impaired driving, and increased use of other illicit substances.

287 ters and their modulation by therapeutic and illicit substances.

288 20 million Americans are current abusers of illicit substances.

289 ints included number of days of use of other illicit substances.

290 come countries, a result in no small part of illicit trade and cheap products from China and other un

291 Combating illicit trafficking of Special Nuclear Material may requ

292 x present in many immune populations and can illicit transcriptional responses that vary among differ

293 ening tests and methods for the detection of illicit treatments of food animals would be useful.

294 levance to HAD because of their clinical and illicit use in patients with AIDS.

295 In the later period, illicit use increased by the following percentage points

296 One of the hallmarks of illicit use of anabolic androgenic steroids (AAS) is dis

297 that body-image pathology is associated with illicit use of anabolic-androgenic steroids (AAS).

298 developed for the routine monitoring of the illicit use of clenbuterol in animal farming.

299 Thus, monitoring the illicit use of rHuEPO among athletes is crucial in ensur

300 highly specific cellular toxicities through illicit, yet highly specific, interactions with the prot