ライフサイエンスコーパス: imbalanced

1 rval responses have many zero values and are imbalanced.

2 ase of proteolytic enzymes and inhibitors is imbalanced.

3 oxic when its production and degradation are imbalanced.

4 the transition states of these reactions are imbalanced, a question which continues to draw attention

5 scoordinate gene expression accompanied with imbalanced accumulation of noncollagenous matrix compone

6 e on GBW (approximately 150 g) or be greatly imbalanced across exposure groups (approximately 25%) to

7 Evidence is growing that imbalanced activation of other TGF-beta receptors couple

8 ia during Parkinson's disease, along with an imbalanced activation of the direct and indirect pathway

9 of appropriate behavioral responses, whereas imbalanced activity (PFC < NAC) results in maladaptive b

10 t symptom severity and the magnitude of this imbalanced activity are correlated.

11 ral autonomic drive during stress results in imbalanced activity in right and left cardiac sympatheti

12 Yet, imbalanced alleles, especially from diploid genome regio

13 transition states for all the reactions are imbalanced, although there is no correlation between the

14 marrow microenvironment of MM patients with imbalanced AML-1A and AML-1B expression can increase bon

15 interleukin-3 (IL-3) was also induced by the imbalanced AML-1A and AML-1B expression in myeloma.

16 y for nonspecific amplicon formation and for imbalanced amplification of different targets, each of w

17 tely suppressed ingestion of both amino acid imbalanced and basal diets.

18 was decreased and bacterial composition was imbalanced and included outgrowth of the Enterobacteriac

19 Nonetheless, imbalanced and incomplete diallels arise frequently, alb

20 ynthetic minority over-sampling technique on imbalanced and multi-label datasets, referred to as ML-S

21 ession of the angiopoietins becomes markedly imbalanced and Tie2 signaling is greatly attenuated.

22 se embryos, synthesis of new H2A and H2Av is imbalanced, and that newly produced H2Av can be recruite

23 way" SPNs (iSPNs); their firing rates became imbalanced, and they disparately engaged in network osci

24 well as glomerular endothelial biology, and imbalanced angiopoietin signaling contributes to glomeru

25 ulate the expression of RNF217 and result in imbalanced apoptosis signalling via HAX1, promoting leuk

26 Feedforward circuits may become imbalanced at low stimulation levels, however, if the ex

27 g log-binomial regression, adjusting for the imbalanced baseline characteristics between the groups.

28 sing hierarchical Cox modeling to adjust for imbalanced baseline characteristics, allocation to dexme

29 ve calls for atypical SNPs, harboring allele-imbalanced binding affinities, that are difficult to gen

30 results in disrupted placental architecture, imbalanced bone development, and losses of functional ne

31 subchondral trabecular bone turnover due to imbalanced bone-resorbing and bone-forming activities is

32 The transition states are all imbalanced but less so than for the reactions of CH3CH=X

33 Half of the meals were nutritionally imbalanced by providing elevated fat (>30% of energy) an

34 cial part of innate immune responses but, if imbalanced, can lead to serious clinical conditions or e

35 sive articular cartilage degeneration due to imbalanced cartilage matrix synthesis and degradation.

36 erforms better than LOH analysis for allelic-imbalanced chromosome regions and normal contaminated sa

37 PUGSVM addresses the problem of imbalanced class separability, small sample size and hig

38 These findings indicate that an imbalanced commissural inhibitory system is a root cause

39 depressive disorder (MDD) has been linked to imbalanced communication among large-scale brain network

40 Our study reveals that an imbalanced competition between the two sides of apoflavo

41 usively shown to be causative agents of RAS, imbalanced composition of the oral microbiota may play a

42 ty within frontoparietal control systems and imbalanced connectivity between control systems and netw

43 inflammatory IL-1beta, indicating a severely imbalanced cytokine milieu in the liver in absence of a

44 mal peripheral T cells through apoptosis and imbalanced cytokine secretion (ie, induction of tumor ne

45 Given the potent pathogenic role of imbalanced cytokine secretion observed in HIV-infection,

46 in C was truly ineffective; they showed that imbalanced cytomegalovirus infection between arms would

47 were detected in both balanced (20 SNPs) and imbalanced data (case:control 1:2 and 1:4, 10 SNPs) in t

48 utilize these features and to deal with the imbalanced data classification problem commonly encounte

49 a, especially with the presence of noise and imbalanced data clusters; (iii) provides a high-level da

50 To deal with the imbalanced data distribution inherent in image annotatio

51 a general method, cluster_boost, that in an imbalanced data setting predicts new minority class memb

52 lance-aware learning techniques to deal with imbalanced data that naturally arise in several genome-w

53 n to be effective in tackling the problem of imbalanced data.

54 AUC), which is an unbiased measure for class-imbalanced data.

55 argued as suitable metric for comparison for imbalanced datasets similar to the one studied here.

56 nicians contradicted equipoise by presenting imbalanced descriptions of trial treatments that conflic

57 imals decrease their intake of an amino acid imbalanced diet (IMB), due in part to a drop in the conc

58 form cortex (APC) on intake of an amino acid imbalanced diet and a basal diet were evaluated in rats.

59 gonist) stimulated feeding of the amino acid imbalanced diet but had no effect on intake of the basal

60 and neuropeptides in response to amino acid imbalanced diet intake.

61 did not affect consumption of the amino acid imbalanced diet.

62 e reduced feeding response to the amino acid imbalanced diet.

63 ributed to the exploitation of nutritionally imbalanced diets such as plant saps or vertebrate blood.

64 After rats ate IAA-devoid or -imbalanced diets, their depleted slices responded to dif

65 When they are restricted to imbalanced diets, they employ regulatory rules that gove

66 short term anorectic response to amino acid imbalanced diets.

67 However, an imbalanced distribution of multiple myeloma is frequentl

68 ion of IRBIT expression in HeLa cells causes imbalanced dNTP pools and altered cell cycle progression

69 These imbalanced dNTP pools promote replication errors in spec

70 he activation of the DNA damage response and imbalanced dNTP pools.

71 licates homeostatic pathways that may become imbalanced during the pathogenesis of T2D or cancer or t

72 Imbalanced early-stage sound level processing could part

73 e are undergoing severe oxidative stress and imbalanced endoplasmic reticulum homeostasis, both of wh

74 Dysfunction of axonal mitochondria and imbalanced energy demand and supply are implicated in de

75 Dysregulated adipocyte physiology leads to imbalanced energy storage, obesity, and associated disea

76 ondrial dysfunction, neuroinflammation or an imbalanced environment of excitation and inhibition in t

77 and MSI was positively correlated with their imbalanced enzymatic activities.

78 An imbalanced evaporation-to-inflow ratio (E/I) was the mos

79 ons arising from a 'final common pathway' of imbalanced excitation to inhibition within cortical netw

80 ricular nucleus (PVN-RVLM) contributes to an imbalanced excitatory/inhibitory function in renovascula

81 Imbalanced expression in 3R-tau and 4R-tau has been foun

82 survival BCL-2 proteins in resistance, their imbalanced expression in infant ALL, and evidence of oba

83 Hyperphosphorylation of tau and imbalanced expression of 3R-tau and 4R-tau as a result o

84 rproduction of proinflammatory mediators and imbalanced expression of anabolic and catabolic genes we

85 oliferation, altered duct morphogenesis, and imbalanced expression of claudin proteins.

86 nic intermittent hypoxia (CIH) results in an imbalanced expression of hypoxia-inducible factor-alpha

87 Defective or imbalanced expression of spliceosomal factors has been l

88 regulated in multiple myeloma (MM) owing to imbalanced expression of the acute myeloid leukemia-1A (

89 to polyinosinic:polycytidylic acid causes an imbalanced expression of the Na(+)-K(+)-2Cl(-) cotranspo

90 of this "NOTCH2-BCR axis" in cGVHD revealed imbalanced expression of the transcription factors IRF4

91 RNAs, one-third of which showed allelically imbalanced expression.

92 imilarity to that of a regular 3D population imbalanced Fermi gas, but with a more drastic departure

93 te Fermi polarons in a two-dimensional, spin-imbalanced Fermi gas, measuring their spectral function

94 chinnikov (FFLO) phases than that using spin-imbalanced Fermi gases.

95 rectly assess the physiological impact of an imbalanced fibrinolytic system on both early and late st

96 find that robust beta-band oscillations and imbalanced firing emerge from implementation of changes

97 ent for the enhanced beta-band oscillations, imbalanced firing, and motor dysfunction in Parkinson's

98 mpact of postoperative mortality, and may be imbalanced for factors important to survival, the true n

99 s, HGPS mutant mice show growth retardation, imbalanced gait and spontaneous fractures.

100 These rearrangements resulted in an imbalanced genomic architecture and translocations of ch

101 uction of beta-globin shRNA (beta-KD) caused imbalanced globin chain production.

102 ton imaging analyses identified elevated and imbalanced glucose metabolism in the Igf2 null mouse.

103 Thus, imbalanced glutamate homeostasis contributes to axonal a

104 e Deltapepck mutant, as a consequence of the imbalanced glycosomal ATP/ADP ratio.

105 balance." We find that parasites form highly imbalanced groups, and that concomitant predation, in wh

106 and CAIV single knockout animals display an imbalanced HCO3 (-) homeostasis, resulting in substantia

107 Bacterial metabolites resulting from an imbalanced homeostasis and dysbiosis play also a crucial

108 of metallic lead, both generated due to the imbalanced I/Pb stoichiometry which could evolve during

109 and pathways that lead to the development of imbalanced immune homeostasis and loss of self-tolerance

110 these findings suggest that induction of an imbalanced immune tolerance in monocytes by P. gingivali

111 T cells to memory T cells, may condition the imbalanced immunoregulation and tolerance in NOD T cells

112 itory ratio of synaptic transmission becomes imbalanced in a manner that correlates highly with the l

113 duced and genealogies are significantly more imbalanced in coding regions and introns when compared t

114 nes whose expression is strain selective and imbalanced in heterozygous F1 mice.

115 CLA(+) TH1/TH2 and TC1/TC2 ratio was highly imbalanced in patients with AD (10 vs 3 [P = .005] and 1

116 ndothelial cell kinase 2 (Tie2) are markedly imbalanced in severe infections associated with vascular

117 nt with the hypothesis that the adaptive and imbalanced increase in AAG and APE1 is a novel mechanism

118 gic emergency response systems that includes imbalanced inflammatory response, acute coagulopathy of

119 lateral synapses, and blunted plasticity and imbalanced inhibition at temporoammonic synapses.

120 ed changes in the two sets of dendrites, but imbalanced input results in differential changes.

121 lidal neurons, which in turn might lead to a imbalanced integration between direct and indirect MSN p

122 We show that an imbalanced interaction between two opposing currents med

123 The imbalanced interactions between clathrin subunit isoform

124 nto various collective states by introducing imbalanced interactions.

125 An imbalanced intestinal homeostasis results in a breach of

126 RECENT FINDINGS: It is known that an imbalanced intestinal microbiota predisposes to CDI, IBD

127 Aneuploidy, an imbalanced karyotype, is a widely observed feature of ca

128 in protecting the cell from toxic effects of imbalanced ketoacid pools.

129 Correcting imbalanced Lands' cycle by knockdown of phospholipase 2

130 at hypoxia-mediated ERK activation underlies imbalanced Lands' cycle by preferentially inducing the a

131 udies have identified a pathological role of imbalanced Lands' cycle in SCD erythrocytes, novel molec

132 mouse findings and further demonstrated that imbalanced Lands' cycle induced LysoPC production direct

133 ncogenic potential of NS remains unclear, as imbalanced levels of NS have been reported to exert grow

134 omosomal alterations, including balanced and imbalanced losses and gains, copy-neutral loss-of-hetero

135 Dyskinesias result from an imbalanced low GPi discharge, a circumstance that may be

136 ately treated have low bone mineral density, imbalanced macronutrients, low fiber intake, and micronu

137 stones are incorporated into chromatin in an imbalanced manner, it can lead to altered gene expressio

138 Imbalanced maternal nutrition during pregnancy results i

139 ying the exact MEGS, particularly for highly imbalanced MEGS.

140 ally, we show that BB0250 depletion leads to imbalanced membrane phospholipid composition in borrelia

141 higher numbers of apoptotic osteocytes, and imbalanced metabolism, leading to defective mineralizati

142 he inefficient use of cellular resources and imbalanced metabolism.

143 relief valve" to alleviate toxic effects of imbalanced metabolism.

144 These results revealed that imbalanced miR-17-92 expression, also mediated by p53, d

145 ls and they hypothesized that this generates imbalanced mitochondrial deoxyribonucleoside triphosphat

146 hondrial pathology triggered by defective or imbalanced mitochondrial dynamics.

147 harboring the rpo41-R129D mutation) displays imbalanced mitochondrial translation, conditional inacti

148 This state is mediated by production of imbalanced molecules, and reactive dicarbonyl compounds

149 Thus, we have identified a specific, imbalanced monocyte signaling profile, with inhibition o

150 When proteostasis is imbalanced, NAC relocalizes from a ribosome-associated s

151 ies, implying that the CI defect leads to an imbalanced NADH/NAD(+) ratio that inhibits mitochondrial

152 tric for this purpose due to the large class-imbalanced nature of the problem.

153 en the very large data volume and the highly imbalanced nature with only small number of active compo

154 s of synapses, aberrant calcium homeostasis, imbalanced neurotransmitter release, and ultimately with

155 synapses, aberrant calcium homeostasis, and imbalanced neurotransmitter release.

156 When imbalanced, NK-like cells promote disease.

157 anel of cell lines with 100 nM folate led to imbalanced nucleotide and AdoMet pools only in cells wit

158 been attributed to the mutagenic effects of imbalanced nucleotide pools and errors made by replicati

159 Limitations include an unblinded trial and imbalanced numbers of participants, favoring controls.

160 eservoir of carbon and energy in response to imbalanced nutritional conditions.

161 human embryos are aneuploid and genomically imbalanced, often as a result of meiotic errors inherite

162 s reported in rodent tissues, whether highly imbalanced or relatively balanced, the amount of 8-oxo-d

163 To deal with highly imbalanced order/disorder ratio, instead of training Dee

164 T cells causes the associated autoimmunity, imbalanced peripheral lymphoid homeostasis, and defectiv

165 We show that imbalanced plasticity corresponds to imposing a regulari

166 Imbalanced plasticity is biophysically plausible and lea

167 Here, we tested in rats whether imbalanced prefrontal neural activity impairs attention.

168 ral beta-amyloid plaques likely results from imbalanced production and removal of amyloid-beta (Abeta

169 the arachidonic acid pathway (leading to an imbalanced production of eicosanoids) have been linked t

170 e cofactor transhydrogenase flux, correcting imbalanced production of NADPH and NADH, were enabled by

171 ell survival and tissue homoeostasis because imbalanced production of reactive oxygen species (ROS) m

172 flammatory cytokine production and induce an imbalanced proinflammatory cytokine environment in multi

173 Providers are randomly assigned to an imbalanced proportion of intervention-arm participants (

174 The inclusion of an imbalanced proportion of patients with active cytomegalo

175 Imbalanced protease activity has long been recognized in

176 protease matched expression may underlie the imbalanced protease activity observed in pathological st

177 Imbalanced protease expression and activities may contri

178 Local excess, or imbalanced, protease activity is one of several possible

179 results suggest mutations in DNMT1 result in imbalanced protein homeostasis through aggresome-induced

180 Imbalanced protein load within cells is a critical aspec

181 circuit model that pools such neurons in an imbalanced "push-pull" manner, to generate orientation-s

182 cholesterol loading of macrophages leads to imbalanced Rac1/Rho activities and impaired chemotaxis.

183 ytical method is developed to adjust for the imbalanced ratio effect.

184 inucleotide phosphate (NADPH) production and imbalanced redox homeostasis in erythrocytes.

185 a small molecule inhibitor R162 resulted in imbalanced redox homeostasis, leading to attenuated canc

186 Furthermore, they have an imbalanced redox state, with downregulation of the antio

187 py alleles can also be inferred from allelic-imbalanced regions by MCP analysis.

188 ample, identifying cancer-associated allelic imbalanced regions in low tumor-cellularity samples or i

189 A fitness cost due to imbalanced replichores has been proposed to provoke chro

190 diate a translational homeostasis that, when imbalanced, results in FXS.

191 prevented from infecting human cells due to imbalanced salt bridges at the hydrophobic virus/recepto

192 , confirming similar findings in other class-imbalanced settings.

193 SD in a warming world have increased because imbalanced sex ratios could potentially threaten populat

194 We further tested effects of imbalanced Shh on apoptosis.

195 n, suggesting that Swe1 activity responds to imbalanced sphingolipid metabolism, in the absence of TG

196 ses of a strongly interacting Fermi gas with imbalanced spin populations.

197 te mixture of ultracold fermionic atoms with imbalanced state populations.

198 The mtDNA alterations led to an imbalanced stoichiometry of mitochondrial respiratory ch

199 raveled a previously unknown link between an imbalanced stoichiometry of the mitochondrial respirator

200 of nucleation-elongation under conditions of imbalanced stoichiometry qualitatively supports the mono

201 olymerizations conducted under conditions of imbalanced stoichiometry.

202 The imbalanced strengthening of connections to flexor, but n

203 itutively active receptors and increased and imbalanced striatal output that is acutely corrected by

204 ght into the elementary pairing mechanism of imbalanced, strongly coupled two-dimensional Fermi gases

205 s encoding myelin proteins, showing that the imbalanced supply of myelin proteins causes the disrupti

206 ity in both layers 2/3 and 5, in addition to imbalanced synaptic excitation and inhibition.

207 This holds for both balanced and imbalanced systems, and we show that it is a generic fea

208 IDO activity that, in turn, correlated with imbalanced Th17/Treg-cell responses to Aspergillus fumig

209 e for the NCCH(2)Y/NCCH=Y(-) systems is more imbalanced than that for the CH(3)Y/CH(2)=Y(-) systems.

210 The excitatory influence of the two eyes is imbalanced to a degree that can be predicted from the se

211 ostly clustered in a posterior zone, receive imbalanced tone-evoked excitatory and inhibitory synapti

212 This finding suggested imbalanced topoisomerase activity in the absence of Top1

213 al for normal epithelial cell functions, and imbalanced up-regulation of CD44 function and/or down-re

214 at distal sites that can become functionally imbalanced upon the introduction of specific pathogenic

215 Most forest nitrogen budgets are imbalanced, with nitrogen inputs exceeding nitrogen outp