ライフサイエンスコーパス: imidate

1 hat nicotinamide and solvent compete for the imidate.

2 xazoline predominantly forms from anti-Z-bis-imidates.

3 Overman's [3,3]-sigmatropic rearrangement of imidates.

4 reaction between cyclopentanol 12 and chiral imidate 30 which was catalyzed by HBF(4) to initially gi

5 ve glycosidation reaction of 13 and glycosyl imidate 30.

6 g the formation of the C2-sulfonium glycosyl imidate 39 as well as oxazoline 37 as key intermediates

7 te 5 and a subsequent coupling reaction with imidate 6 to produce disaccharide 7, which after deacety

8 w of sulfur imidation methods, classified by imidating agents and compounds with a related behaviour.

9 Copper(I) imidate and amidate complexes of chelating N,N-donor lig

10 and a formal [3+2] cycloaddition between an imidate and cyclopropenone.

11 selective protection/deprotection protocols, imidate and n-pentenyl glycosylations, and functional gr

12 osidation are investigated with thiopyridyl, imidate, and thiotolyl donors as well as differently cro

13 For the first time the N-H-imidates are demonstrated to be good directing groups in

14 enyl)imidoyl chlorides and the corresponding imidates are easily prepared and can be utilized as comp

15 s the development of S-benzimidazolyl (SBiz) imidates as versatile building blocks for oligosaccharid

16 on the nature of the amine nucleophile, the imidates can react either as the free-base or the hydroc

17 ctions implied that the isolated amidate and imidate complexes are intermediates in the reactions of

18 alyst system consisting of water-soluble Pd--imidate complexes has been enployed for the Suzuki-Miyau

19 pper-carboxylate, copper-amidate, and copper-imidate complexes were performed.

20 glycosyl bromides and activation of the OFox imidates could be conducted in a regenerative fashion.

21 alogs (via in situ conversion of alcohols to imidates, directed C-H amination, and hydrolysis to NH2)

22 Only a catalytic amount of the OFox imidate donor and a Lewis acid activator are present in

23 The OFox imidate donor is constantly regenerated upon its consump

24 Both thioglycoside and Schmidt imidate donors (1.5 equiv) have been employed successful

25 Reaction with a chiral imidate favors a mechanism that proceeds through a carbo

26 utral imidazole form of His187 and the N1-O2 imidate form of uracil.

27 nd radical scavengers, we propose that boron-imidates form under the basic reaction conditions that a

28 sigmatropic rearrangements, leading to vinyl imidate formation.

29 ng existing methods for converting amides to imidates gave inconsistent or irreproducible results, so

30 , 2) are reported using anomeric hydroxy and imidate glucuronate intermediates.

31 ore, mechanistic studies illustrate that the imidate group adjacent to the benzylic position plays cr

32 selectively activating the C(2)-benzylidene imidate group in the presence of the anomeric sulfide gr

33 es follows the trend Cu(II)-amidate > Cu(II)-imidate > Cu(II)-benzoate.

34 The SBiz imidates have been originally developed as a new platfor

35 single flask protocol with formation of the imidate in situ is demonstrated, providing a convenient

36 nyl)benzamides affords high yields of cyclic imidates, instead of the previously reported isoindolin-

37 action mechanism and the modes by which SBiz imidates interact with various promoters of glycosylatio

38 lation of an amide to form the corresponding imidate is a common synthetic problem, often resulting i

39 Several allylic imidate motifs were evaluated also.

40 lladium complex coordinates to both the C(1)-imidate nitrogen and C(2)-oxygen of the trichloroacetimi

41 a novel mechanism in which chelation of the imidate nitrogen to form a cationic palladium(II) interm

42 ocycles were typically prepared by either an imidate or a Weinreb amide route (Schemes 1 and 2), the

43 ected in situ to provide derivatives (methyl imidates or N,N-dimethylamidines) that were amenable to

44 Dibenziodolium hydrogen sulfate, bis(triflyl)imidate, or triflate can be readily converted to various

45 from seven residues and is tilted out of the imidate plane of PGH toward the re face.

46 The use of the imidate precursor for the synthesis of N-substituted qui

47 nes presented herein enable direct access to imidate radicals, allowing their first use for H atom ab

48 These amidates and imidates reacted much more slowly with chloroarenes, inc

49 lylic amines via Overman's [3,3]-sigmatropic imidate rearrangement, and subsequent one-pot deprotecti

50 indicates a significant contribution of the imidate resonance form of PGH.

51 onfirmed by spectroscopy, the (Z)-vinylogous imidate salt predominates.

52 n peptide settings possible, we developed an imidate salt protecting strategy that employs methyl tri

53 The imidate salt strategy enables, for the first time, remot

54 tained via hydrolysis of an unique tricyclic imidate side product of the Ugi reaction.

55 This novel imidate strategy facilitates late-stage oxidations in a

56 lated peptide and is proposed to involve the imidate to generate beta-stereochemistry.

57 mide, via intermediacy of a sensitive methyl imidate, to the N-acyl aminal reminiscent of psymberin.

58 Disubstituted allylic bis-imidates undergo Lewis acid catalyzed or spontaneous cyc

59 A carboxamide oxime and imidate were synthesized from CTCRI by the addition of h

60 ns wherein 3,3-difluoro-3H-indol-2-yl (OFox) imidates were found to be key intermediates.

61 2,2,2-Trifluoro- and trichloroethyl imidates, which are easily prepared by reaction of a nit

62 rmation is achieved starting from anti-E-bis-imidates while trans-oxazoline predominantly forms from

63 oelectronic eight-centered rearrangements of imidates would also be allowed.