ライフサイエンスコーパス: imino

1 Observation of imino (1)H resonances is an established method for evalu

2 at 3 (MK-8931), a diaryl amide-substituted 3-imino-1,2,4-thiadiazinane 1,1-dioxide derivative, is a h

3 synthesis of N-fused and 3,4-disubstituted 5-imino-1,2,4-thiadiazole derivatives has been achieved th

4 Overall, 5-imino-1,2,4-thiadiazoles are presented here as new molec

5 Here, we report substituted 5-imino-1,2,4-thiadiazoles as the first small molecules ab

6 for the preparation of 1-(N-ribofuranosyl)-6-imino-1,6-dihydropyrimidin-4-amines 3 or 4-(N-ribofurano

7 d, but the n = 3 ring hydrolyzes to form a 3-imino-1-oxoisoindoline derivatized crown ether species.

8 ,9-dihydro-2H-purin-2,6-diamines 21-24 and 6-imino-1-phenyl-8,9-disubstituted-6,9-dihydro-1H-purin-2-

9 he bimetallic 2,7-di-[(2,6-diisopropylphenyl)imino]-1,8-naphthalenediolato group 10 metal polymerizat

10 minoanthrone, 9-imino-10-silaxanthone, and 9-imino-10-germaxanthone fluorophores.

11 nm Stokes shifts based on 9-iminoanthrone, 9-imino-10-silaxanthone, and 9-imino-10-germaxanthone fluo

12 ethylphenyl)amino)-4-((2,6-diisopropylphenyl)imino)-2-pentene) , for the controlled ROP of various OC

13 opylphenyl)amido)-4-((2,6-diisopropylphenyl)-imino)-2-pentene], chemo- and regioselective polymerizat

14 aneously rearranges in the dark to singlet 6-imino-2,4-cyclohexadien-1-ketene on the time scale of se

15 5-exodig cyclization to give the 2-[1-aryl-5-imino-2-phenyl-1H-imidazol-4(5H)-ylidene]malononitriles

16 dium(II) carbenoid, leading to a transient 1-imino-2-vinylcyclopropane intermediate which rapidly und

17 subunit blockers suramin (8,8'-[carbonylbis[imino-3,1-phenylen ecarbonylimino(4-methyl-3,1-phenylene

18 base (2 equiv) to give in one step 3-aryl-4-imino-3,4-dihydroquinazoline-2-carbonitriles in 53-81% y

19 cular C-N cyclization of 3-(2-bromophenyl)-4-imino-3,4-dihydroquinazoline-2-carbonitriles.

20 0.008, using bath-applied 200 nm SR 95531 [6-Imino-3-(4-methoxyphenyl)-1(6H)-p yridazinebutanoic acid

21 with the single-crystal X-ray structure of 4-imino-3-phenyl-3,4-dihydroquinazoline-2-carbonitrile.

22 NF279 (8,8'-[carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylim

23 ts reactive blue 2, NF279 (8,8'-[carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylim

24 00 microM), and NF449 [4,4',4,4-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis-ben

25 s, and its analog 4,4',4'',4'''-[carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino))] tetrakis-be

26 een and identified a tris-aryl substituted 2-imino-5-arylidenethiazolidin-4-one, compound 1, as an in

27 olysis and acidic deprotection to generate 2-imino-5-carboxy-3,4-dihydropyrimidines in a four-step se

28 -LTQ-Orbitrap MS and NMR as N-(4-carbamoyl-2-imino-5-oxoimidazolidin)formamido-N-methoxyacetic acid (

29 H 8 led to the formation of the respective 2-imino-5-oxoimidazolidines, confirming that guanine deriv

30 -disubstituted-9H-purin-6-amines 27-31 and 6-imino-8,9-disubstituted-6,9-dihydro-1H-purin-1-amines 32

31 in redox behavior of the monofunctional bis(imino)acenaphthene (BIAN) and bifunctional tetrakis(imin

32 ed functionalization of the redox-active bis(imino)acenaphthene (BIAN) ligand class has been explored

33 Furthermore, the structure reveals that the imino acetamido group of TK40 acts as an alpha-amino aci

34 disulfanyl]-2-[(1,3-dimethyl-1H-pyrazol-5-yl)imino]acetonitr ile (8a) gave 4,6,10,12-tetramethyl-6H-p

35 iethylamino)disulfan-yl]-2-[(1H-pyrazol-5-yl)imino]acetonitrile (8a).

36 ht serve in relaying a H(+) from the product imino acid =NH(2)(+) group bound on the flavin Re-side t

37 gnetic resonance was used to assign the free imino acid as (3S,5S)-5-chloropiperazate, distinct from

38 ro-tRNAPhe and Phe-tRNAPro, we show that the imino acid proline and not tRNAPro imposes the primary e

39 The imino acid proline is a poor donor and acceptor for pept

40 tide bond synthesis by most amino acids, the imino acid proline is a poor substrate for protein synth

41 The looser superhelical structure of the non-imino acid region of collagen triple helices combined wi

42 Since collagen has a high content of imino acid residues, the cumulative effects of cis-trans

43 ts 10/3 superhelical properties, whereas the imino acid rich N- and C-terminal regions adhere to a 7/

44 The non-canonical imino acid, (2S,4S)-4-aminoproline (amp), was used to sp

45 ace of collagen molecules, it is likely that imino acid-aromatic CH...pi interactions are important i

46 1032) structure reveals that the central non-imino acid-containing region adopts 10/3 superhelical pr

47 ically pre-treated bone gelatines had higher imino acids (proline and hydroxyproline) contents compar

48 ntained glycine as the major amino acid with imino acids (proline and hydroxyproline) of 194-195 resi

49 Thus, rigid imino acids are unfavorable within a break, despite thei

50 The structure shows that the multiple non-imino acids make several types of direct intrahelical as

51 interaction between aromatic amino acids and imino acids within the triple helix is also supported by

52 and other D-amino acids to the corresponding imino acids.

53 always flanked by a specific distribution of imino acids.

54 ize the triple helix compared to the P and O imino acids.

55 d profile of BSG showed a high percentage of imino acids.

56 xylamine O-vinyl ethers and imino ketones or imino aldehydes along the reaction pathway were determin

57 N,O-divinyl hydroxylamines to corresponding imino-aldehydes (Paal-Knorr intermediates) revealed that

58 The absolute configuration of the imino-aldol adducts has been determined.

59 to high ee has been developed via asymmetric imino-aldol and aldol reactions, respectively, starting

60 approach involving asymmetric Mannich-type (imino-aldol) reactions of methyl phenylacetate with N-te

61 u, Ni, Co, Fe, Mn, Cr) with 2 equiv of alpha-imino alkoxide salts K(RR'COCNtBu) (R = Me, tBu; R' = iP

62 diastereo- and enantiocontrol, forming beta-imino amides that can be deprotected to the primary beta

63 he close proximity between the intra-residue imino and amino protons.

64 A range of biologically significant imino and amino sugars [1,4-dideoxy-1,4-imino-D-allitol,

65 by the ATP synthase inhibitor AMP-PNP (gamma-imino ATP, a nonhydrolyzable ATP analog) and Mg(2+)/ADP.

66 thiol oxidants and inhibited by Mg(2+)/gamma-imino ATP.

67 m Ala, Phe, or hPhe gave the hydrates of the imino beta-keto-alpha,alpha-difluorosulfonamides.

68 The alpha-(N-hydroxy/aryl)imino-beta-oxodithioesters are readily accessible by the

69 ] heterocyclization of alpha-(N-hydroxy/aryl)imino-beta-oxodithioesters with in situ generated Cu-car

70 ed transporter protein, DHSA, is fused with (imino)biotinylated cargo proteins via an avidin adaptor

71 mine with ethyl diazoacetate mediated by the imino-BOROX catalyst to give aziridine-2-carboxylic este

72 aldehyde and the concomitant formation of an imino-BOROX chiral Bronsted acid and finally the reactio

73 Two new C-nucleoside analogues, BCX4430, an imino-C-nucleoside, and GS-6620, a phosphoramidate deriv

74 precursors for the formation of metal-bound imino carbene intermediates.

75 n achieved by reaction of rhodium-stabilized imino-carbenes with furans.

76 e in the pKas for deprotonation of the alpha-imino carbon from 17 to 11 to 6.

77 ide ion-catalyzed deprotonation of the alpha-imino carbon increases from 7.5 x 10(2) to 3.8 x 10(5) t

78 ate constants for deprotonation of the alpha-imino carbon of the adduct between 5'-deoxypyridoxal (1)

79 10(-3) s(-1) for deprotonation of the alpha-imino carbon of this cofactor-glycine adduct (pKa = 17 b

80 ation of the rate of deprotonation the alpha-imino carbon.

81 energy barrier to transfer a proton between imino centers in [II-H](+) is 1 order of magnitude lower

82 beta-carbon methylation to give the primary imino complex cis-[Re(PNP(tBu)-HN horizontal lineCC(Me)P

83 Betalamic acid condenses with imino compounds (cyclo-DOPA or its glucosyl derivatives)

84 cant imino and amino sugars [1,4-dideoxy-1,4-imino-D-allitol, 3,6-dideoxy-3,6-imino-L-allonic acid, (

85 e to aldehyde derivatives of 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) and its enantiomer (LAB) and su

86 nd GP were both inhibited by 1,4-dideoxy-1,4-imino-d-arabinitol, but only GP was inhibited by isofago

87 We combined isofagomine and 2,5-anhydro-2,5-imino-D-glucitol active site binding substructures with

88 d 2,5-dideoxy-3-O-alpha-d-glucopyranosyl-2,5-imino-d-mannitol (9) to act as an inhibitor of GlgE.

89 h 2,5-dideoxy-3-O-alpha-D-glucopyranosyl-2,5-imino-D-mannitol (DDGIM), an oxocarbenium mimic, was sol

90 e; alpha-homonojirimycin and 2,5-dideoxy-2,5-imino-d-mannitol were the major iminosugars determined.

91 this regard, we show here that deshydroxy-1-imino derivatives of acridine (i.e., dihydroacridinedion

92 etin glycopentoside, XXI.4,4'-dihydroxy-3,3'-imino-di-benzoic acid, XXV.quercetin-3-O-rhamnogalactosi

93 - and monozinc catalysts, coordinated by bis(imino)diphenylamido ligands, show remarkable activities

94 another nitrogen containing intermediate, 4-imino-DMQ(6).

95 ation, aza-Henry, aza-Morita-Baylis-Hillman, imino-ene, Mannich-type, and cycloaddition reactions, as

96 3+2] cycloaddition of methyl acrylate and an imino ester prepared from l-leucine t-butyl ester hydroc

97 c compounds to the N-perfluorobutanesulfinyl imino ester provided arylglycines with very high diaster

98 of alpha-chloroglycine ester as a practical imino ester surrogate.

99 The utility of this activated N-sulfinyl imino ester was demonstrated for reactions that gave eit

100 ylate provided the N-perfluorobutanesulfinyl imino ester.

101 s various functional groups, including keto, imino, ester, ether, and cyano.

102 talyzed Povarov-type reaction of fluorinated imino esters and furans is described.

103 alyzed 1,3-dipolar cycloaddition (1,3-DC) of imino esters and nitroalkenes, with alpha,beta-unsaturat

104 , and applications of the reactions of alpha-imino esters and related compounds in organic synthesis,

105 Due to the adjacent ester group, alpha-imino esters are more reactive relative to other types o

106 alpha-Imino esters are useful precursors for the synthesis of

107 alyzed the reactions of aldehydes with alpha-imino esters under mild conditions and afforded anti-Man

108 For the reactions of ketones with alpha-imino esters, (R)-3-pyrrolidinecarboxylic acid was an ef

109 E)-tert-butyl 6-bromo-2-hexenoate with alpha-imino esters.

110 ceed with bridging adenine bases in the rare imino form (A*), spanning the Rh-Rh bond at equatorial p

111 The imino form A* of adenine in DNA may result in AT-->CG tr

112 bly reduced value as compared to that of the imino form of 9-EtAdeH.

113 he active site, suggesting that it is the N6-imino form of cADPR that is hydrolyzed by CD38.

114 imately 7.0 in CD3CN-d3), as compared to the imino form of the free dinucleotide.

115 he presence of the adenine bases in the rare imino form, due to bidentate metalation of the N6/N7 sit

116 60% of neutral KP1212 is present in the enol-imino form.

117 tautomerism of the amino derivatives to the imino forms likely accounts for their loss in biological

118 midazolin-2-imino group is an N-heterocyclic imino functionality that derives from the class of compo

119 Thus, this imino group is an excellent choice for thermodynamic sta

120 The imidazolin-2-imino group is an N-heterocyclic imino functionality tha

121 rectly measure pK(a) values for the Ade38 N1 imino group of a hairpin ribozyme in distinct conformati

122 In aprotic solvent, the imino group that forms ortho to the boronic acid or boro

123 of methyl phenyldiazoacetates with an ortho-imino group, prepared from o-aminophenylacetic acid, to

124 ddition, we showed that carboxyl, amino, and imino groups are nearly equally distributed over beta-sh

125 c acids and proteins where amide, amino, and imino groups are rapidly moving between a closed solvent

126 stem (-8G) and that the guanine 6-keto and 7-imino groups at both positions are essential for binding

127 s of Phe and of positively charged amino and imino groups remain similar.

128 impact of protium-deuterium exchange of the imino hydrogen on the free energy of RNA basepair openin

129 The yield of the imino hydroxylamine increases at the expense of the imin

130 ually converting C-PTIO to the corresponding imino hydroxylamine, C-PTI-H.

131 ventually converted into imino nitroxide and imino hydroxylamine.

132 via comproportionation with the nitronyl and imino hydroxylamines.

133 A new class of highly acidic confined imino-imidodiphosphate (iIDP) Bronsted acids catalyze th

134 kene aminocarbonylation pathway involving an imino-isocyanate intermediate is proposed and supported

135 r [1,4] H atom shift from the nitrene to the imino ketene occurs by tunneling, on the triplet manifol

136 of N-alkenylhydroxylamine O-vinyl ethers and imino ketones or imino aldehydes along the reaction path

137 dideoxy-1,4-imino-D-allitol, 3,6-dideoxy-3,6-imino-L-allonic acid, (3R,4S)-3,4-dihydroxy-L-proline, 1

138 The iminosugar 1,4-dideoxy-1, 4-imino-l-arabinitol (LAB) inhibits arabinoxylan arabinofu

139 enzonitriles, and aryl halides produces beta-imino lactams that then afford beta-keto lactams by acid

140 2,6-bis(((4-(1H-benzo[d]imidazol-2-yl)phenyl)imino) methyl)-4 methyl phenol]) could sense PPi anion t

141 igand 2-[[(3,5-di-tert-butyl-2-hydroxyphenyl)imino]methyl]-4,6-di-tert-butylphenol 1.

142 ounds, 2,4-dichloro-6-{(E)-[(3-methoxyphenyl)imino]methyl}phenol (DPMP).

143 results demonstrate the essentiality of the imino moiety as well as the importance of its interactio

144 copy to measure directly the pK(a) of the N1-imino moiety in the context of hairpin ribozyme crystals

145 We propose that the imino moiety of A9 promotes a key water-mediated contact

146 investigate these residues, we replaced the imino moiety of each base with N1-deazaadenosine.

147 vorable TS interaction energy (Munchnones or imino-Munchnones) or the smallest TS distortion energy (

148 itions of mesoionic 1,3-dipoles (Munchnones, imino-Munchnones, and phospha-Munchnones) with alkynes o

149 eveloped an empirical relation that predicts imino N-H vector orientations from the heavy-atom coordi

150 calculations indicate that deviations of the imino N-H vectors in RNA U and G bases result from H-bon

151 and revealed the pi-donating N-heterocyclic imino (NHI) and sigma-donating silyl groups as key facto

152 hilic attack of the carbene lone pair on the imino nitrogen (pathway "a") or on the carbon atom in th

153 " process is triggered by protonation of the imino nitrogen and concomitant conformational change of

154 number of catenated methylene units between imino nitrogen atoms).

155 es advantage of the strong dependence of the imino nitrogen chemical shift on hydrogen bonding and in

156 ding some of the Mg(2+) assignments near the imino nitrogen of guanine, is suggestive of the existenc

157 ith the pyridine nitrogen of the PLP and the imino nitrogen of the Schiff base, respectively.

158 lack of any detectable chemical exchange by imino nitrogen rotating frame spin relaxation (R1rho) ex

159 functional role of cytosine's keto group and imino nitrogen.

160 ith a methyl group as the substituent on the imino nitrogen.

161 ation dispersion for the hydrogen-bond donor imino nitrogens in G and T residues.

162 droxylamine and is eventually converted into imino nitroxide and imino hydroxylamine.

163 ydroxylamine increases at the expense of the imino nitroxide as the ratio [AS](0)/[nitronyl nitroxide

164 -PTIO to form (*)NO(2) and the corresponding imino nitroxide, C-PTI.

165 onyl nitroxide yields only the corresponding imino nitroxide, nitronyl nitroxide can discriminate NO

166 , leading to the formation of the respective imino nitroxides and hydroxylamines via a complex mechan

167 (*)NO(2) oxidizes the nitronyl and imino nitroxides to their respective oxoammonium cations

168 ide (C-PTIO), which yields the corresponding imino nitroxides, is widely used for NO detection (mainl

169 The imino NMR spectra of pre-let-7 loops and LREs contain re

170 group(s) directly linked to a pulling cyano, imino, or phosphoimino group, as well as those in which

171 increases the basicity of the pulling cyano, imino, or phosphoimino group.

172 n the tautomeric equilibrium toward the rare imino-oxo tautomer of cytidine stabilizes the f(5)C34*A

173 using a non-natural substrate, benzaldehyde imino-oxy acetic acid (BIAA).

174 blocked by NO-711 (1-[2-[[(diphenylmethylene)imino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinec arboxyli

175 and Watson-Crick pairs are all head-to-head imino-paired (cis Watson-Crick/Watson-Crick).

176 n-Crick), with AG pairs that are only weakly imino-paired.

177 O-pentafluorobenzoyl oxime esters generates imino-Pd(II) intermediates, which undergo 5-exo cyclizat

178 The reaction of LGa (L = Dipp(4-(Dipp-imino)pent-2-en-2-yl)amide; Dipp: 2,6-diisopropylphenyl)

179 The N-substituted imino pharmacophore was therefore extended to fill the g

180 The triazole linked o-imino phenol appended calix[4]arene conjugate (L) has be

181 Four 4-[[(4-nitrophenyl)methylene]imino]phenols (2a-d) were synthesized.

182 The new chromophore, benzothiophene imino-phenylacetonitrile (BTIPA), was synthesized in fou

183 4-methylthio-2-oxobutyric acid and 2-hydroxy-imino phenylpyruvic acid, both of which reduced polyposi

184 rved ring expansion by insertion of a chloro(imino)phosphine into a P-N bond of the P-N-C-N framework

185 Increasing the pK(a) value of the imino proton by reduction of its 5,6-double bond results

186 r in the two structures are characterized by imino proton exchange and nuclear magnetic resonance spe

187 xternal catalysis exchange mechanisms on the imino proton exchange rates is analyzed.

188 characterizing the temperature dependence of imino proton exchange rates of individual basepairs.

189 nternal Psi-A, Psi-G and Psi-U pairs, the N3 imino proton is hydrogen bonded to the opposite strand n

190 NMR studies of imino proton lifetime, solvent accessibility, and NOE co

191 to the opposite strand nucleotide and the N1 imino proton may also be hydrogen bonded.

192 Imino proton NMR data provided evidence that elements of

193 The temperature-dependent imino proton NMR spectrum of oxoG modified DNA confirms

194 oresis, equilibrium ultracentrifugation, and imino proton NMR, we are able to show that these modific

195 e versus temperature melting experiments and imino proton nuclear magnetic resonance (NMR).

196 The observed imino proton nuclear magnetic resonance resonances and F

197 The line width of the imino proton of the ClU residue is substantially greater

198 eased level of chemical exchange for the ClU imino proton of the ClU-A base pair, the ClU residue is

199 Functional group substitution shows that the imino proton on the N1 is critical, suggesting a possibl

200 ding affinity was measured by monitoring RNA imino proton resonances for some of the compounds that s

201 Thermal denaturation and imino proton solvent exchange experiments reveal that th

202 lly greater than that of the corresponding T imino proton; however, this difference is not attributed

203 This is surprising, given that imino-proton exchange rates show that basepairs in a DNA

204 e pair opening were measured for most of the imino protons in the P1 duplex using the base catalysts

205 exchange cross peaks for several base-paired imino protons in the RNA yielded an apparent k(on) of 60

206 ive imaging agents, since their exchangeable imino protons resonate at 5-6 ppm from the water proton

207 erized by measuring the rates of exchange of imino protons with solvent protons as a function of the

208 Psi has two hydrogen donors (N1 and N3 imino protons) and two hydrogen bond acceptors because t

209 cenaphthene (BIAN) and bifunctional tetrakis(imino)pyracene (TIP) ligands have been explored by treat

210 The bis(imino)pyridine 2,6-(2,6-iPr2-C6H3N=CPh)2-C5H3N ((iPr)BPD

211 Using just 1 mol % FeCl(2), bis(imino)pyridine 6 (1 mol %), CO(2) (atmospheric pressure)

212 explore the electronic structure of the bis(imino)pyridine alkyl-substituted imides.

213 blish competitive cyclometalation of the bis(imino)pyridine aryl substituents during catalytic turnov

214 are evaluated in the broader context of bis(imino)pyridine base metal chemistry and the influence of

215 de) = 1/2) and a closed-shell, dianionic bis(imino)pyridine chelate (S(PDI) = 0) is favored for the S

216 light the importance of the redox-active bis(imino)pyridine chelate for enabling catalytic cyclizatio

217 Fe(I)-Fe(III) catalytic cycle where the bis(imino)pyridine chelate remains in its one-electron reduc

218 l substituent into the 4-position of the bis(imino)pyridine chelate, enabling the facile hydroboratio

219 o-electron reduction of the redox-active bis(imino)pyridine chelate.

220 Pr)PDI)Mn, which features a pentadentate bis(imino)pyridine chelate.

221 (S(Fe) = 2) with neutral, redox-innocent bis(imino)pyridine chelates.

222 Planar S = (1/2) kappa(3)-bis(imino)pyridine cobalt alkene and tetrahedral kappa(2)-bi

223 nating functionality with a C1-symmetric bis(imino)pyridine cobalt catalyst is described and has been

224 Enantiopure C(1)-symmetric bis(imino)pyridine cobalt chloride, methyl, hydride, and cyc

225 e cobalt alkene and tetrahedral kappa(2)-bis(imino)pyridine cobalt diene complexes were observed by E

226 malgam reduction of the aryl-substituted bis(imino)pyridine cobalt dihalide complexes ((Ar)PDI)CoCl(2

227 series of cationic, neutral, and anionic bis(imino)pyridine cobalt dinitrogen compounds establish Co(

228 Aryl-substituted bis(imino)pyridine cobalt dinitrogen compounds, ((R)PDI)CoN2

229 The aryl-substituted bis(imino)pyridine cobalt methyl complex, ((Mes)PDI)CoCH3 ((

230 Bis(imino)pyridine cobalt methyl complexes are active for th

231 A bis(imino)pyridine cobalt-catalyzed hydroboration of termina

232 Bis(imino)pyridine complex [Ni{2,6-(ArN=CMe)(2)C(5)H(3)N}Cl]

233 The change in field strength of the bis(imino)pyridine coupled with the placement of the alkyl l

234 (S(Fe) = 0) with a closed-shell singlet bis(imino)pyridine dianion (S(PDI) = 0), demonstrating that

235 Bis(imino)pyridine iron alkyl complexes bearing beta-hydroge

236 family of cationic, neutral, and anionic bis(imino)pyridine iron alkyl complexes has been prepared, a

237 Aryl-substituted bis(imino)pyridine iron and cobalt dihalide compounds, when

238 Reduced bis(imino)pyridine iron and cobalt dinitrogen compounds have

239 Bis(imino)pyridine iron bis(alkoxide) complexes have been sy

240 ce of such pathways to chain transfer in bis(imino)pyridine iron catalyzed olefin polymerization reac

241 Catalytically competent bis(imino)pyridine iron diene and metallacycles relevant to

242 The bis(imino)pyridine iron dinitrogen complex (((i)Pr)PDI)Fe(N(

243 CHR (R = Ph, p-Tolyl, (t)Bu, Cy), to the bis(imino)pyridine iron dinitrogen complex, ((iPr)PDI)Fe(N(2

244 Addition of biphenylene to the bis(imino)pyridine iron dinitrogen complexes, ((iPr)PDI)Fe(N

245 The bis(imino)pyridine iron dinitrogen compound, ((iPr(TB))PDI)F

246 The bis(imino)pyridine iron dinitrogen compounds, ((iPr)PDI)Fe(N

247 Three new N-alkyl substituted bis(imino)pyridine iron imide complexes, ((iPr)PDI)FeNR ((iP

248 ffraction on all three alkyl-substituted bis(imino)pyridine iron imides established essentially plana

249 in isolation of catalytically competent bis(imino)pyridine iron metallacycle intermediates.

250 he molecular structures of the resulting bis(imino)pyridine iron metallacycles were established by X-

251 pared to the electronic structure of the bis(imino)pyridine iron N-aryl imide counterparts.

252 A bis(imino)pyridine ligand scaffold was employed to synthesiz

253 Reaction of a phenyl-substituted bis(imino)pyridine ligand that is reduced by two electrons,

254 on effected directly at the redox-active bis(imino)pyridine ligand without an overall oxidation state

255 b), in which (Ph)I2P(2-) is a tridentate bis(imino)pyridine ligand, reacts with anilines to give the

256 Thus, the formal oxidative process is bis(imino)pyridine ligand-based (one electron is formally re

257 oth the iron center and the redox-active bis(imino)pyridine ligand.

258 ion is observed to template a tridentate bis(imino)pyridine ligand.

259 etal catalysts, coordinated by optimized bis(imino)pyridine ligands, show promise for industrial appl

260 ligand followed by N-H bond activation, bis(imino)pyridine modification, and H2 loss.

261 Treatment of the bis(imino)pyridine molybdenum eta(6)-benzene complex ((iPr)P

262 Me(3)), is chelate-based, resulting in a bis(imino)pyridine radical anion (S(PDI) = 1/2) antiferromag

263 mpounds antiferromagnetically coupled to bis(imino)pyridine radical anions.

264 Structure-activity relationships on bis(imino)pyridine substitution were also established with 2

265 quantites of 1,2-diarylhydrazines to the bis(imino)pyridine vanadium dinitrogen complex, [{((iPr)BPDI

266 ss 1,2-diarylhydrazine, formation of the bis(imino)pyridine vanadium imide amide compounds, ((iPr)BPD

267 (59)Co center, suggesting a principally bis(imino)pyridine-based SOMO.

268 lic half-sandwich complexes [M(p-cymene)(azo/imino-pyridine)X](+) where M = Ru(II) or Os(II) and X ho

269 al calculations suggest that the quinone and imino-quinone monoacetal coupling partners are exclusive

270 5'-neighbor base pair G(5) x C(20), the G(5) imino resonance remained sharp at 55 degrees C but broad

271 '-neighbor A(8) x T(17) base pair, the T(17) imino resonance was severely broadened at 55 degrees C.

272 reveals that the intensity of several of the imino resonances increases upon encapsulation.

273 The X(7) and Y(19) imino resonances were observed at 65 degrees C.

274 e show that sparse distance constraints from imino resonances, which can be readily obtained from rou

275 intramolecular cyclopropanation of an alpha-imino rhodium(II) carbenoid, leading to a transient 1-im

276 Our data suggest that, relatively, imino-rich sequences maintain the canonical triple-helic

277 The neutral imino-semiquinone, 4,6-di-tert-butyl-2-tert-butylimino-s

278 Imino spectral analysis of a (15)N-labeled central G cle

279 id-catalyzed rearrangement of the isolated 2-imino-spirochromenofurans 5 to 2-amino-spirochromenofura

280 erent positions of an orthogonally protected imino sugar as a common precursor.

281 straightforward protocol for the assembly of imino sugar containing nucleosides, establishing a new r

282 Analysis of an imino sugar inhibitor is consistent with tight binding o

283 ex and synthesis and evaluation of novel aza/imino sugar inhibitors.

284 This imino sugar was promising but had an EC(50) against DENV

285 his trend is potent hSGLT3 activation by the imino sugars 1-deoxynojirimycin (DNJ), N-hydroxylethyl-1

286 y, GBA2 is reversibly inhibited by alkylated imino sugars that are in clinical use or are being devel

287 e related imidazolidin- and benzimidazolin-2-imino system.

288 )2{d(ApA)}, only the anti orientation of the imino tautomer is possible.

289 e synthesized to create models for the 1',4'-imino tautomer of the 4'-aminopyrimidine ring of thiamin

290 TolF)2{d(ApA)} induces formation of the rare imino tautomer of the bases with a concomitant substanti

291 te the C or mC prior to deamination via an E-imino tautomer of the C or mC or by a nontemplated mecha

292 H deprotonation of the metal-stabilized rare imino tautomer, which takes place at pKa approximately 7

293 was hypothesized to originate from its amino-imino tautomerism, which would explain its ability to ba

294 ral possible mechanisms, including the amino-imino tautomerization of the substrate base that may exp

295 u prepared Zn(2+) complex of triazole linked imino-thiophenyl conjugate of calix[4]arene, [ZnL], was

296 nalog 3-benzothienyl-l-alanine (Bta) with an imino-to-sulfur substitution in the five-membered ring.

297 ATP analogs such as adenosine 5'-(beta,gamma-imino)triphosphate (AMP-PNP) and adenosine 5'-O-(thiotri

298 phate) (ATPgammaS), adenosine 5'-(beta,gamma-imino)triphosphate (AMP-PNP), and guanosine 5'-3-O-(thio

299 presence of ATP and adenosine 5'-(beta,gamma-imino)triphosphate but not by ADP.

300 iotriphosphate) and adenosine 5'-(beta,gamma-imino)triphosphate can stimulate helicase activity, as c