ライフサイエンスコーパス: immense

1 lly, biologically, physically and culturally immense.

2 The opportunity is immense.

3 tributable to common neurological disease is immense.

4 umber of potentially accessible materials is immense.

5 , the global burden of this pathogen remains immense.

6 , the global burden of this pathogen remains immense.

7 As a result, an immense academic attention has focused on the valorisati

8 Pooling and analysis of the immense amount of data generated by the major carotid en

9 The immense amount of data generated in these studies poses

10 The immense and growing repositories of transcriptional data

11 ed capabilities for proteome measurements is immense and is now driving both new strategies and instr

12 trial surface, agricultural lands provide an immense and near-term opportunity to address climate cha

13 edicine and the prospects for the future are immense and potentially society changing.

14 ermans to mix.' Interest in the congress was immense and subsequent international congresses (London,

15 The complexities of airway management are immense and though great strides have been made to impro

16 portance of this translational regulation is immense, and affects such processes as cell growth, deve

17 Highly mutable complex pathogens present an immense antigenic diversity that continues to challenge

18 the urine of a patient can be the source of immense anxiety.

19 The consequences of ROS cycling in immense aphotic zones representing key sites of nutrient

20 e of integral membrane proteins within their immense, architecturally complex dendritic arbors.

21 ate about initial human migration across the immense area of East Polynesia has focused upon seafarin

22 cells are critical for the elimination of an immense array of microbial pathogens.

23 An immense array of naturally occurring biological systems

24 ity for neuroprotection and drug delivery is immense, as we show in preclinical and proof-of-concept

25 thways that do not occur, are found to be of immense assistance to comprehend the hitherto poorly und

26 assembly of sugar-derived LMWGs has received immense attention because of their propensity to furnish

27 Proton conducting materials have garnered immense attention for their role as electrolytes in fuel

28 bject of topological materials has attracted immense attention in condensed-matter physics because th

29 ynthesis, and not surprisingly have garnered immense attention.

30 Vaccines that have been proven to be of immense benefit in saving lives offer us a new fringe be

31 Coral reefs support immense biodiversity and provide important ecosystem ser

32 ycosides represent a group of molecules with immense biological applications and implications.

33 or different plants, and characterizing this immense biological chemodiversity is a challenge for est

34 ing isomerization reactions, and are thus of immense biological significance.

35 This capability complements the immense body of steady-state transcript measurements and

36 creased number of periosteal osteoclasts and immense bone loss in wild type mice but not in Tlr2-defi

37 These chemosensors present immense brightness and fluorescence enhancement (chelati

38 Reactivation of dormant infections causes an immense burden of morbidity and mortality in the world a

39 disease, and cystic fibrosis, which cause an immense burden of morbidity and mortality.

40 In order to reduce the immense burden of tuberculosis, new vaccines or vaccinat

41 challenge of oxygenating the whole train is immense but has been successfully accomplished.

42 ome, the scale of the project is potentially immense but nevertheless feasible in the context of a pa

43 calving mass loss remains unconstrained, yet immense calving losses have been observed.

44 ntibody variable domains are critical to the immense capacity of the immune repertoire.

45 There is immense cellular and molecular heterogeneity in biologic

46 ic responses to these changes constitutes an immense challenge for ecologists.

47 The immense challenge of annotating the entire mouse genome

48 Despite immense challenges, the country has a sensitive surveill

49 ns to achieve consistent proportions despite immense changes in size.

50 er, such an understanding is hindered by the immense chemical complexity of environmental mixtures of

51 sfully identified and treated, there will be immense clinical benefits, accompanied by cost savings.

52 entifying metastasis-promoting factors is of immense clinical interest, as the prognosis for patients

53 logy is commercially available and given the immense clinical need, clinical trials in this AD treatm

54 etermine the functional beta-cell mass is of immense clinical relevance.

55 gnals that regulate beta-cell function is of immense clinical relevance.

56 ains, we found that NG2-glia are produced as immense clonal clusters whose number of cells is about o

57 We replicate the association in the IMMEnSE cohort including 772 patients, and a University

58 The field of proteomics suffers from the immense complexity of even small proteomes and the enorm

59 connectomes has been a challenge due to the immense complexity of global brain networks.

60 However, this remains challenging due to the immense computational cost of sampling events on biologi

61 levels, probably contributes to the brain's immense computational efficiency.

62 e experimental findings firmly establish the immense computational power of a single neuron, and thus

63 ringency of migration most likely imposes an immense constraint on normal mesenchymal cell mobility i

64 ogenic causes of obesity in humans have made immense contribution toward the understanding of the bra

65 Studies of budding yeast have made immense contributions to this progress.

66 lular pathogens is generally accomplished by immense CTL expansion and activation, which can destroy

67 tolerance was among these and has engendered immense curiosity over the years.

68 carbon at globally significant rates in the immense dark ocean.

69 In this work we analyze a part of the immense data set, in particular radiocesium contaminatio

70 The study also illustrates the immense diagnostic progress since the first regional sur

71 s, vaccines, and therapeutics contributes to immense disease burden.

72 The immense diversity coupled with differential clinical eff

73 We find immense diversity of both haploid and diploid gene forms

74 ding the key structures and behaviors in the immense diversity of carbon allotropes.

75 Evidence is mounting that the immense diversity of microorganisms and animals that liv

76 Despite the immense diversity of papillomavirus types, our understan

77 The immense diversity of resistance genes in the human micro

78 Our observations provide insight into the immense diversity of targets utilized by YopJ-like effec

79 The immense diversity of Ub substrates, as well as the compl

80 Our findings bridge the immense divide between the temporal resolutions of these

81 There has been an immense drive in modern microscopy towards miniaturizati

82 nter (WTC) on September 11, 2001, created an immense dust cloud followed by fires that emitted soot i

83 ularly prone to eutrophication, which causes immense ecological and economic problems.

84 ibbean and western Atlantic, resulting in an immense ecological damage.

85 lination by insects, an ecosystem service of immense economic and conservation importance, depends on

86 tural gas to liquids (Bio-GTL) represents an immense economic opportunity.

87 st popular caffeine-containing beverage with immense economic, medicinal, and cultural importance.

88 However, immense efforts have been undertaken to further the unde

89 In contrast to immense efforts to block the signaling of cancer progres

90 s possess a duplicated lobe structure due to immense elaboration of the processes of class III Kenyon

91 Pulsar systems accelerate particles to immense energies.

92 y, unless this one solution so dominates the immense ensemble of all solutions that its probability i

93 ence, the space of tertiary conformations is immense; existing methods to identify native-like confor

94 The immense expansion and specialization of the immune syste

95 oor of the mouth into the cavum ventrale, an immense fascial pocket between the body wall and overlyi

96 etric ligand-receptor binding into a new and immense field of applications: the interaction of solute

97 ined by a few occasional droughts triggering immense fires.

98 /hybridization of carbon is hence a topic of immense fundamental and technological interest.

99 Gram-positive pathogens exhibit an immense genetic repertoire to adapt and develop resistan

100 unknown functions (ORFans) encoded by their immense genetic repertoire.

101 Instead, the bulk of these immense genomes is composed of highly heterogeneous, rel

102 d on the observation that, although there is immense genomic variation, every infective virion is res

103 alignant, and ischemic disorders, remains an immense health burden despite new molecular therapies.

104 g shortfalls to antimicrobial resistance and immense health inequities.

105 Stem cell therapy provides immense hope for regenerating the pathological heart, ye

106 gies are in phase 2 and 3 studies, providing immense hope that better treatment will be imminently an

107 Gene therapy (GT) has offered immense hope to individuals who are visually impaired be

108 acilitated by the temporary grounding of two immense icebergs that (i) erected a veritable fence sepa

109 HIV-1 poses immense immunological challenges to the humoral immune r

110 ion in humans and other mammals, showing the immense impact of cadherins on normal as well as pathoge

111 Yet, many studies have revealed the immense impact of ocular misalignment on psychosocial va

112 High throughput technology is having an immense impact on biological research and one of the maj

113 This technique has had an immense impact on biomedical research over the past two

114 ar and cellular processes of vision may have immense impact on research and clinical diagnostics.

115 in the EIC construction process and can have immense impact on the detection of EIC peaks.

116 ule to a biological macromolecule, which has immense implications in drug development.

117 o-date knowledge in the field and review the immense implications that this global infection has for

118 e vectors of parasitic and viral diseases of immense importance for public health.

119 This discovery has had immense importance for the understanding, diagnosis, and

120 Despite their immense importance in neurobiology, glia remain understu

121 gard to neuronal Cl- regulation, despite its immense importance in the generation of inhibitory synap

122 dependence in population growth rates is of immense importance to ecological theory and application,

123 Due to its immense importance, the present review has been formulat

124 the Eliashberg function of a material, is of immense importance.

125 on of this gene within the human brain is of immense importance.

126 h the burden of IC on the American public is immense in both human and financial terms, there is no c

127 lly known to be an insulator could induce an immense increase in the selective photo-oxidation of dif

128 The immense intercellular and intracellular heterogeneity of

129 Li-rich oxides continue to be of immense interest as potential next generation Li-ion bat

130 C-di-GMP, in particular, has attracted immense interest because it is found in many bacteria an

131 ishmania major infection in mice has been of immense interest because it was among the first models t

132 ffinity in protein-ligand interaction are of immense interest because of obvious practical applicatio

133 ces of magnetically active materials attract immense interest because of the idea of exploiting fermi

134 involving turn on/off principles have gained immense interest due to their specificity and sensitivit

135 ed bimetallic nanoparticles are currently of immense interest due to their unique electronic, optical

136 -catalytic events by using nano-probes is of immense interest due to unique optical properties of met

137 As such, an immense interest exists for the development of therapies

138 lly precise copper nanoclusters (NCs) are of immense interest for a variety of applications, but have

139 rbohydrate display on the cell surface is of immense interest for diagnosis and therapy.

140 success of cancer immunotherapy has produced immense interest in defining the clinical contexts that

141 as pharmaceutical targets, there has been an immense interest in developing therapeutic monoclonal an

142 targets for cancer drug discovery, prompting immense interest in epigenetic-focused, medicinal chemis

143 orated the causal debate of MS and generated immense interest in the patient and scientific communiti

144 Recent research has witnessed immense interest in the use of recombinant enzymatic met

145 Despite immense interest in using antimalarials as autophagy inh

146 Despite their immense interest, no simple method exists to gain insigh

147 Despite immense interest, the mechanism by which the 2 enzymes e

148 and transfection of cells has recently seen immense interest.

149 acyl carbanion processes has been an area of immense interest.

150 the mechanism of collagen degradation is of immense interest.

151 d to tubulin and cause mitotic arrest are of immense interest.

152 basis of such interactions is the subject of immense interest.

153 llow them to chain into complex molecules of immense length.

154 completed within the next few years, despite immense logistic and political difficulties, and may ult

155 The solar wind blows an immense magnetic bubble, the heliosphere, in the local i

156 t clinical trials have demonstrated that the immense majority of acute promyelocytic leukemia (APL) p

157 The immense majority of genes are alternatively spliced and

158 Despite the immense medical implications, the genetic and molecular

159 Despite the immense medical importance of amyloid fibrils, no atomic

160 These findings underscore the immense microbial diversity and functional potential tha

161 arch suggests that these environments harbor immense microbial diversity.

162 The immense molecular diversity of neurons challenges our ab

163 on is a complex, multiscalar phenomenon with immense moral and economic costs.

164 g model systems for epigenetics due to their immense morphological and behavioral plasticity.

165 ker data, especially sequence data, imply an immense multiple testing burden.

166 integrated multi-omics and immunity PCA - an immense national resource to interrogate, target, and in

167 Harnessing the immense natural diversity of biological functions for ec

168 adily toward clinical trials, spurred by the immense need to find reparative therapeutics for central

169 The brain vasculature forms an immense network such that most neural cells are in conta

170 Plant roots are colonized by an immense number of microbes, referred to as the root micr

171 An immense number of post-translational modifications on hi

172 Although the immense number of sequence combinations makes wholly ran

173 ot limited by dispersal as a result of their immense numbers and microscopic size.

174 ions continuously in time and space over the immense ocean areas they inhabit is challenging but esse

175 ntified patient-level research data presents immense opportunities to all stakeholders involved in ca

176 lved problem", while others might argue that immense opportunity remains untapped or simply inaccessi

177 ithin tissues they have colonized has raised immense optimism that these cells may provide functional

178 Thus, realizing the immense pathologic significance of Bmi-1 in cancer, we w

179 Mammals host gut microbiomes of immense physiological consequence, but the determinants

180 for nitric oxide, an endogenous molecule of immense physiological importance to animals.

181 The immense plasticity of bone marrow cells allows them to p

182 Bacterial chromosomes are immense polymers whose faithful replication and segregat

183 eforms to improve health equity will receive immense popular support, governmental commitment, and in

184 d laparoscopic surgery in urology has gained immense popularity with the daVinci system, but a lot of

185 Immense populations of viruses are present in the human

186 Humans are colonized by immense populations of viruses, which metagenomic analys

187 anti-inflammatory fat cell hormone that has immense potential as a therapeutic target for a multitud

188 es and natural biological processes and have immense potential as novel nanomaterials.

189 g and selective detection devices which hold immense potential as point of care (POC) tools.

190 VDR ligands also show immense potential as therapeutic agents for autoimmune d

191 ent of resistance in bacteria and hence bear immense potential as therapeutic agents to tackle multid

192 CRISPR-Cas genome-editing methods hold immense potential as therapeutic tools to fix disease-ca

193 mploying aptamers as capture probes, holding immense potential for application in detection of a broa

194 This strategy holds immense potential for durable patient-specific tissue-en

195 walls (DWs) above room temperature provides immense potential for exploitation of their DW motion in

196 axis-related alkane bioaccumulation, and has immense potential for fast and high-throughput screening

197 TOF-SIMS holds immense potential for investigating the subcellular mech

198 Together, these results demonstrate the immense potential for reassortment to generate viral div

199 Induced pluripotent stem cells (iPSCs) offer immense potential for regenerative medicine and studies

200 The field also has immense potential for the development of medical treatme

201 mergence of functional metadevices has shown immense potential for the practical realization of highl

202 tically engineered cells into the CNS offers immense potential for the treatment of several neurologi

203 ided by emerging stem cell technology, holds immense potential for the treatment of valvular heart di

204 ization, and application of Adipogel provide immense potential for tissue engineering and regenerativ

205 powerful gene silencing technology that has immense potential for treating a vast array of human ail

206 pid membrane-embedded nanochannel system has immense potential nanotechnological and biomedical appli

207 Our findings highlight the immense potential of dynamical models, mathematics, and

208 oaches to development challenges, and by the immense potential of innovation and new technologies to

209 To realize the immense potential of large-scale genomic sequencing afte

210 eous catalytic processes and demonstrate the immense potential of novel nonlinear spectromicroscopies

211 Our findings demonstrate immense potential of this device for automated breast tu

212 is investigation may be key to realizing the immense potential of widely pursued nanocomposites.

213 Cave animals are one group with immense potential to address the mechanisms of evolution

214 Thus, SEGA (3a) bears an immense potential to be a novel gastroprotective agent a

215 sults indicate that the developed sensor has immense potential to be used as accurate online Hg(0) va

216 mat with appropriate polymeric carriers have immense potential to become an RNAi-based platform suita

217 The method has thus immense potential to develop as rapid, selective, simple

218 id perovskite multijunction solar cells have immense potential to realize power conversion efficienci

219 CRISPR/Cas9 holds immense potential to treat a range of genetic disorders.

220 Despite their immense potential, the ability to control the dispersion

221 approach for glycan structural analysis with immense potential.

222 ution molecular genetic analysis would be of immense practical application in the study of human dise

223 However, despite the immense practical importance of fibre-optic communicatio

224 frameworks and mesostructured oxides are of immense practical utility for gas storage, separations a

225 In addition to being of immense practical utility, the ability to evolve protein

226 In recent years, an immense progress has been made in understanding the link

227 Despite immense progress in antiretroviral therapy (ART) scale-u

228 Despite immense progress in our understanding of the structure-f

229 cades of neuroscience research have produced immense progress in the methods available to understand

230 n that remains robust today and has inspired immense progress in understanding how natural selection

231 The demonstrations show SWNTs' immense promise as a low-cost and scalable TFT technolog

232 Thus, SIP has immense promise for discovering microorganisms responsib

233 and versatile genome-editing tool and holds immense promise for future therapeutic applications.

234 This proof of concept developed herein holds immense promise for the ability to regulate gene activit

235 These data reveal the immense promise of in situ albumin targeting for develop

236 This result shows the immense promise of nanofiber supported thin-film composi

237 es represent major global health problems of immense proportion.

238 nstitutes a personal and societal tragedy of immense proportions.

239 talline Zeo-GO for detection of ketamine has immense prospective for field-testing platforms.

240 loviruses, Ebola and Marburg, usually garner immense public attention, often with a sensationalist be

241 ental to the health of the individual and an immense public health and economic burden.

242 Tuberculosis (TB) remains an immense public health problem in the Republic of Korea d

243 nt polysaccharide on Earth and represents an immense quantity of stored energy for biofuel production

244 However, how and when this immense radiation of animals originated is unclear.

245 For a process intimately connected to an immense range of physiological processes, the molecular

246 ovide a novel cell-free system that uses the immense regenerative power of ES cells while avoiding th

247 Although protein adsorption on solids is of immense relevance, experimental limitations mean there i

248 ithania somnifera (Ws), a medicinal plant of immense repute known to synthesize a large array of biol

249 Immense research work is going on for detection of molec

250 bacterial genome sequences have revealed an immense reservoir of biosynthetic gene clusters, sets of

251 To date, only a small fraction of this immense resource has been characterized because of the d

252 Given the immense risk posed by widespread environmental pollution

253 uch as Brucella spp. in dairy products is an immense risk to public health.

254 tion factor binding sites; all of which play immense roles in global gene expression regulation.

255 Metallic nanostructures are of immense scientific interest owing to unexpectedly strong

256 Despite the immense sequence diversity among OSS cell piRNAs, our an

257 ral response, a property consistent with the immense sequence variation noted for NSP1 proteins.

258 s with liver microsomes is suggested to have immense significance in the design of one-step, green bi

259 Despite the immense significance retrotransposons have had for genom

260 Given the immense size and complexity of eukaryotic genomes, this

261 Their immense size and intricate geometry pose many unique cel

262 omprehensive proteomic profiling include the immense size and structural heterogeneity of the proteom

263 millions of deaths annually, and present an immense social and economic burden.

264 The immense social and economic impact of bacterial pathogen

265 human-like emotions is controversial and of immense societal concern [1-3].

266 ellular parasites of humans and animals with immense socio-economic and health impacts.

267 information that systematically explores the immense space of small structural elements and reveals m

268 es of these 'hot Jupiters' are heated by the immense stellar irradiation.

269 as concentrations as permafrost thaw exposes immense stores of frozen carbon (C) to microbial decompo

270 Because immense structural and electrostatic diversity at a sing

271 amily have an essential role in creating the immense structural diversity of triterpenoids across the

272 ma mansoni and Schistosoma japonicum inflict immense suffering as agents of human schistosomiasis.

273 It creates, within an immense swath of river corridor well upstream of the SFB

274 c complexity in eukaryotes ushered in by the immense technological advances in high-throughput sequen

275 Plant synthetic biology promises immense technological benefits, including the potential

276 olloid composites, an important challenge of immense technological relevance.

277 th huMIF and plasmodial MIF, thus bearing an immense therapeutic potential against proinflammatory re

278 To address the immense therapeutic potential of miRNAs and their antago

279 Despite the immense therapeutic value of this biosynthetic pathway,

280 al benefits of native ecosystems are clearly immense, they remain largely unquantified for all but a

281 pharmaceutical companies alike have devoted immense time and capital into the design of nanocarriers

282 ability of early neural arrangements over an immense time span.

283 isolates have not yet been obtained, have an immense, untapped reservoir of enzymes that could help a

284 including Caenorhabditis elegans has been of immense use in identifying nonredundant components of co

285 Despite its immense value and in contrast to transcriptomics, only a

286 Sorghum has immense value as a staple food item for humans in Africa

287 atasets under identical conditions can be of immense value both to biomedical researchers and clinici

288 inst profiles of several proteins would have immense value in drug discovery.

289 are examples where single-cell cloning is of immense value.

290 Despite immense variability across languages, people can learn t

291 Humans perceive an immense variety of chemicals as having distinct odors.

292 at in its structural diversity parallels the immense variety of structural options available for poly

293 nses is the ability to discriminate among an immense variety of substances by means of antibodies (Ab

294 An immense variety of sugars and glycosidic linkages leads

295 Providing high sensitivity and immense versatility while being minimally perturbing to

296 The immense volume and rapid growth of human genomic data, e

297 subsequent osteoporosis and fracture risk is immense with potential far-reaching effects in patient q

298 unities: if they exist, the implications are immense with regard to understanding subsurface environm

299 technology is still at its toddler stage and immense works are still in progress to increase the volu

300 cs by the addition of sugars may explain the immense, yet tightly regulated, variability of the remod