ライフサイエンスコーパス: immune function

1 odontal, cardiovascular, renal, hepatic, and immune function).

2 le, we show how Ab affinity modulates TRIM21 immune function.

3 affect microvascular flow, permeability, and immune function.

4 at increased risk of disease associated with immune function.

5 ignals can define intestinal homeostasis and immune function.

6 y deregulates a network of genes involved in immune function.

7 ween the human urinary metabolome and innate immune function.

8 athetic nervous system activity can modulate immune function.

9 PM2-mediated Ca(2+) signaling and limit host immune function.

10 us macaques to investigate how status alters immune function.

11 ell subsets and in early-life airway mucosal immune function.

12 , and the resultant restoration of antitumor immune function.

13 blood immune cells and early airway mucosal immune function.

14 whether PD-L1 on this population influences immune function.

15 ntext of ER stress without disrupting normal immune function.

16 rforming in vitro studies assessing cellular immune function.

17 -term sepsis-induced alterations in cellular immune function.

18 pacts many aspects of host biology including immune function.

19 ng cell structure, extracellular matrix, and immune function.

20 sion levels of a number of genes involved in immune function.

21 tic endothelial cells (LECs) are involved in immune function.

22 pathways involved in neural development and immune function.

23 ates that microbes have a large influence on immune function.

24 g a search for sepsis-induced alterations in immune function.

25 atures relevant to asthma, inflammation, and immune function.

26 ey trans-kingdom principles of NLR-dependent immune function.

27 nd serve as secondary messengers involved in immune function.

28 ion of peripheral B lymphocytes and impaired immune function.

29 site can affect either treatment efficacy or immune function.

30 characteristics, including those related to immune function.

31 whether chemomechanical coupling influences immune function.

32 unity in the gut is important for modulating immune function.

33 ted 474 genes not previously associated with immune function.

34 ticularly in patients with defects in innate immune function.

35 d placebo was observed in measures of innate immune function.

36 may reactivate in individuals with impaired immune function.

37 that provide natural feedback regulation of immune function.

38 loration as targets for boosting host innate immune function.

39 hat dLAN has transgenerational influences on immune function.

40 hogens express virulence factors that impair immune function.

41 key regulators of B cell fate decisions and immune function.

42 s niche is critical for reconstituting their immune function.

43 arburg VP40 assembles progeny and suppresses immune function.

44 itis (RA) do not reverse underlying aberrant immune function.

45 ole for SEPP1 in macrophage polarization and immune function.

46 has been shown to be promising at restoring immune function.

47 abetes, allergic airway disease, and altered immune function.

48 tract infections, indicating impaired local immune function.

49 m, postoperative weight gain, and effects on immune function.

50 t Escherichia coli, as a functional assay of immune function.

51 ating this transcription factor critical for immune function.

52 tution, including antigen-dependent adaptive immune function.

53 in after degranulation and reduced cytotoxic immune function.

54 l signaling, and evaluation of the resultant immune function.

55 rily related to glucocorticoid signaling and immune function.

56 xhaustion, and senescence known to influence immune function.

57 respiratory tract infections and to support immune function.

58 S, suggesting that wild-type HTT has a novel immune function.

59 the consequences of circadian variations on immune function.

60 ic ablation of core clock components impairs immune function.

61 essive, acute stress can temporarily enhance immune function.

62 ons such as glucose and lipid metabolism and immune function.

63 ncreased incidence of cancer due to impaired immune function.

64 of the TBK1-mTORC1 axis in control of innate immune function.

65 al categories, including both immune and non-immune functions.

66 balancing different physiological roles and immune functions.

67 ve both pathologic autoimmune and protective immune functions.

68 f several other reflexes regulating discrete immune functions.

69 T lymphocytes with innate- or adaptive-like immune functions.

70 tum is a visceral adipose tissue with unique immune functions.

71 the inhibition of macrophage activation and immune functions.

72 cient Ag recognition and consequently strong immune functions.

73 r effector cell receptors and perform potent immune functions.

74 toxic potential and protective antibacterial immune functions.

75 TSLP isoforms are responsible for 2 opposite immune functions.

76 e complexity of cell behavior in relation to immune functions.

77 of realistic contaminant mixtures on various immune functions.

78 lling events resulting in a diverse array of immune functions.

79 Viruses can evolve quickly to defeat host immune functions.

80 ression and M. tuberculosis-induced monocyte immune functions.

81 iated with gradual deterioration of adaptive immune function, a hallmark of which is the profound los

82 We investigated 9 loci involved in different immune functions (ADAM33, ADRB2, CD14, IL13, IL4, IL4R,

83 ped as a therapeutic agent to restore innate immune function after liver injury.

84 of the GIT microbiota in regulating adaptive immune function against systemic viral infections during

85 sceral hypersensitivity, altered mucosal and immune function, altered gut microbiota and altered cent

86 More viable immune functioning among the elderly, as indicated by th

87 r regulatory locus that likely has a role in immune function and a locus regulating hippocampal long

88 luding a lack of efficacy in fully restoring immune function and a requirement for life-long treatmen

89 Biomarkers of immune function and anemia vary little with parity or pa

90 As knowledge of immune function and appreciation of immunodeficiency has

91 E) impairs the gut's absorptive capacity and immune function and causes decelerations in statural gro

92 iated keratinocytes, comprising keratinocyte immune function and cellular structure, was found to be

93 uirements for miRNAs in ILC2 homeostasis and immune function and compared the global miRNA repertoire

94 understanding of the genetic basis of human immune function and dysfunction, we performed an express

95 and in EAE mice, correspondent with reduced immune function and EAE CNS pathology.

96 axis coordinates developmental remodelling, immune function and energy allocation in larval amphibia

97 ized expression of multiple genes regulating immune function and epithelial integrity in Glp1r(-/-) r

98 Arsenic has been linked to disrupted immune function and greater infection susceptibility in

99 he gut microbiome plays an important role in immune function and has been implicated in several autoi

100 effects in white blood cells that influence immune function and health outcomes.

101 Decline in immune function and inflammation concomitantly develop w

102 and 26 proteins implicated in cancer (80%), immune function and inflammatory response (40%), cell gr

103 uring chronic Ag settings partially restores immune function and is now used clinically to treat a va

104 iretroviral therapy (HAART) has improved the immune function and life expectancy in HIV-infected pati

105 elation between longitudinal measurements of immune function and lung-cancer risk in people living wi

106 n conjunction with ART treatment can restore immune function and may reduce viral reservoirs during c

107 in many aspects of human biology, including immune function and metabolism.

108 about how genital microbiota influence host immune function and modulate disease susceptibility.

109 have prominent roles in pathways other than immune function and overall the effect sizes were minima

110 lity to interfere with certain mechanisms of immune function and pathogenicity.

111 istimed feeding has functional relevance for immune function and provide further evidence for the int

112 pects of phero-perception, stress responses, immune function and regulation of gene expression that s

113 e the relationship between early life innate immune function and serum vitamin D.

114 clude that GIMAP6 plays a role in modulating immune function and that it does this by controlling cel

115 al role for Cu and Zn intoxication in innate immune function and their direct bactericidal function.

116 might affect long-term mortality by changing immune function and thus potentially increasing the risk

117 lation-based networks that are implicated in immune function and tumor development pathways.

118 e distribution that may well influence tumor immune function and underlie escape mechanisms from curr

119 This hampers our understanding of immune function and undermines our confidence in this im

120 the impact of these environmental factors on immune function and, when known, on alloimmune function,

121 d in brain development, synaptic plasticity, immune function and/or schizophrenia, showing some conve

122 n older age may be indicative of more viable immune functioning and be protective against certain cau

123 he metaexposome in the context of early-life immune functioning and describe how various aspects of a

124 outside the teleost MHC), implying distinct immune functions and conserved roles in shaping MHC path

125 IFN-gamma is a major regulator of immune functions and has been shown to induce liver-stag

126 d new light on its role in the modulation of immune functions and in its participation in the host re

127 PKcs regulate a genetic program with diverse immune functions and promote inflammasome activation and

128 he innate immune response affects downstream immune functions and, ultimately, the outcome of infecti

129 w cytometry to determine the level of innate immune function, and associated the findings with diseas

130 en environmental microbiota, gut microbiota, immune function, and asthma development.

131 r in their activation state, contribution to immune function, and capacity to proliferate in vivo.

132 The thesis that EPA impacts on anabolism, immune function, and clinical outcomes post-esophagectom

133 T cell phenotype, immune function, and CLL cell immunosuppressive capacity

134 plains how these metabolic setups facilitate immune function, and discusses the emerging evidence tha

135 ta can modulate gastrointestinal physiology, immune function, and even behavior.

136 truation, insulin resistance, alterations of immune function, and neuroendocrine dysfunction, among o

137 copper (Cu) are essential for optimal innate immune function, and nutritional deficiency in either me

138 gastrointestinal microbiome, development of immune function, and predisposition to allergic sensitiz

139 trations and malaria infection as indices of immune function, and telomere lengths as an overall meas

140 ciations between methamphetamine (meth) use, immune function, and the dynamics of HIV and cytomegalov

141 related with expression of genes involved in immune function, and were sufficient to modulate inflamm

142 the largest organ in the body with important immune functions, and accumulation of drug delivery syst

143 re recruited to the glioma environment, have immune functions, and can release a wide array of growth

144 romosome leads to deficient intellectual and immune function are not well understood.

145 s of the circadian clock, but its effects on immune function are unknown.

146 s its expression levels return to normal and immune functions are restored when the inflammatory resp

147 ered membrane structure and augmented innate immune function as evidenced by resistance to invasion b

148 Corticosterone treatments affected immune function, as both chronic and acute exposure supp

149 ressive therapy in liver recipients based on immune function assay results.

150 An immune function assay shows promise for identifying soli

151 ing responses and can contribute to aberrant immune function associated with disease, has emerged as

152 okine/cytokine activity and inflammatory and immune functions associated with carcinogenesis.

153 vicular fluid (GCF) as surrogate measures of immune function at subcrestally placed dental implants a

154 Therapeutic efforts to skew immune function away from excessive help for B cells and

155 emory CD4(+) T cells, which are critical for immune function, but has little effect on activated/prol

156 of immunology, used as a model of mammalian immune function, but how well immune responses of labora

157 FR2, Tnfrsf1b) regulates multiple aspects of immune function, but little is known about its role in t

158 rast, human ISG15 was shown to have critical immune functions, but not in antiviral immunity.

159 e role of iPLA2beta in peritoneal macrophage immune function by comparing wild type (WT) and iPLA2bet

160 and their receptors play a critical role in immune function by directing cell-specific movement.

161 radioactive iodine and also direct cellular immune function by engaging endogenous antibodies as an

162 Moreover, antibiotic treatment impairs immune function by inhibiting respiratory activity in im

163 IgG antibodies mediate a diversity of immune functions by coupling of antigen specificity thro

164 n of HIV-1 strengthens DC-mediated antiviral immune functions by simultaneously triggering Th17 expan

165 Regulation of stress and immune functions by the glucocorticoid receptor (GR) is

166 Immune function correlated with regional transcriptional

167 cessive AHR ligand degradation on intestinal immune functions could be counter-balanced by increasing

168 cell senescence is thought to contribute to immune function decline, but the pathways that mediate s

169 tral memory phenotypes (TCM), or to suppress immune function, depending on the concentrations and oth

170 ng of how the amount of tonic signal impacts immune function, describing novel tools that have moved

171 It is generally accepted that impaired immune function due to immunosuppression is a primary ca

172 ptic plasticity, glial cell development) and immune functions (e.g., immune system activation, leukoc

173 us suggesting that virus replication affects immune function even in the context of this clinically b

174 racterized BAFFR-related innate and adaptive immune functions following infection with vesicular stom

175 S. mutans, thus representing a novel innate immune function for salivary gel-forming mucins.

176 ese findings identify a new important innate immune function for the PPARalpha signaling pathway in r

177 Enriched immune function gene expression as defined by our predic

178 on the expression of any nine or more of 14 immune function genes at or above the 0.40 quantile for

179 Increased expression of a subset of immune function genes may provide a means of predicting

180 that increased RFS was linked to a subset of immune function genes.

181 s with similarly rapid increases in cellular immune function had IL-6 levels that tended to decrease

182 Altered immune function has been demonstrated in astronauts duri

183 Our understanding of immune function has benefited greatly from mouse models

184 distinct phenotypic populations with unique immune functions, however the mechanism by which these p

185 to correct murine CD40L expression restored immune function; however, treated mice developed lymphop

186 increased expression of genes with important immune functions (i.e., GAS6, ALOX15B, FCGR2B, LAIR1).

187 tratumoral lymphocytes and directly suppress immune function, I reevaluate the passive lymphatic vess

188 he viral B19 molecule exerts some control of immune functions.IMPORTANCE It is of special importance

189 The effect of HIV on immune function in aging is relatively unknown.

190 brood food production in workers, and proper immune function in all female bees.

191 through P2X7 receptors (P2X7Rs) to modulate immune function in both inflammasome-dependent and -inde

192 These results indicate that immune function in bumblebees is affected by neonicotino

193 Hazard ratios for diseases associated with immune function in children delivered by acute and elect

194 cytokine response is commonly used to assess immune function in critically ill patients.

195 Studying immunity and immune function in ecology and evolution requires field

196 (MSCs) can stimulate angiogenesis and modify immune function in experimental RVD.

197 ic concentrations of PBDEs are able to alter immune function in frogs; however, further research is n

198 ntify SOCS1 as a novel target to improve the immune function in HIV-infected persons.

199 clusion that suppression of PD effluent cell immune function in human subjects by standard PD fluid i

200 ity and to develop new strategies to enhance immune function in older humans.

201 a clinically meaningful recovery of humoral immune function in patients with CLL.

202 C may be an efficient strategy for enhancing immune function in patients with HIV.

203 ablation resulted in broad reconstitution of immune function in stressed T cells, inhibition of indiv

204 ence suggests that gut microbiota influences immune function in the brain and may play a role in neur

205 on between neonicotinoid exposure and innate immune function in the bumblebee Bombus impatiens, which

206 lications for modulating complement-mediated immune function in the microenvironment and on HCV-harbo

207 an increased risk of disease associated with immune function in the offspring, but these studies have

208 Our study highlights the role of innate immune function in thymic regeneration and restoration o

209 plant stanol ester consumption improves the immune function in vivo in asthma patients.

210 ool for the study of human hematopoiesis and immune function in vivo.

211 odents, yet little is known about rhythms of immune functions in humans and how they are affected by

212 persistent in vivo levels of LPS on specific immune functions in humans in the absence of chronic vir

213 (IL-17A) and CD8(+) T cells regulate diverse immune functions in microbial infections, malignancies,

214 xpression of IL-15 correlated with cytolytic immune functions in patients with B-cell lymphoma and fa

215 egative cohort allowed us to assess cellular immune functions in the context of different subclinical

216 eplicable gene networks enriched for diverse immune functions including cytotoxicity, viral response,

217 r involvement in the regulation of essential immune functions, including activation of the AIM2 infla

218 cell interactions and developed suppressive immune functions, including production of indoleamine 2,

219 As a consequence, canonical mucosal immune functions, including tolerance and protective imm

220 definite NASH were associated with abnormal immune function, intestinal cholesterol absorption, and

221 This suggests that HIV influences immune function irreversibly, with several pathways that

222 press IFNlambda4 expression, suggesting that immune function is dependent on other IFNL family member

223 a form of SCID in which a minimal degree of immune function is preserved), as well as craniofacial a

224 mere shortening in age-associated decline of immune function is unknown.

225 in arginine methylation on the regulation of immune functions is virtually unknown.

226 Immunosenescence, an age-related decline in immune function, is a major contributor to morbidity and

227 ipokine linking appetite, energy balance and immune function, is required for ECM pathology and its l

228 Altered immune function, lifestyle factors, or shared etiology m

229 f CD28 and its family members and ligands to immune function, many aspects of CD28 biology remain unc

230 ninfected patients, implying that preserving immune function may improve cardiovascular outcomes in H

231 induced during developmental plasticity, and immune function may provide a common mechanistic process

232 MM development, strategies aimed to increase immune functions may have important therapeutic implicat

233 risk factors that, in addition to modulating immune function, may also converge to act on the vascula

234 gut microbiome, intestinal permeability, gut immune function, motility, visceral sensation, brain-gut

235 Such a critical innate immune function necessitates ion participation.

236 gen species, closely mimicking the defective immune functions observed in beta-thalassemia patients.

237 y which neonicotinoids may impact the innate immune function of bumblebee pollinators in wild and agr

238 Cactin in the mammalian immune response, the immune function of Cactin in insects has not been descri

239 We report a novel extraribosomal innate immune function of mammalian ribosomal protein L13a, whe

240 proteins into phagosomes is critical for the immune function of this organelle.

241 ptive functions of cDCs revealed that innate immune functions of cDCs are insufficient to maintain ho

242 In teleost fish, the immune functions of mannan-binding lectin (MBL) associat

243 iradical defense system that neutralizes the immune functions of neutrophils.

244 tudied Muc19(-/-) mice for changes in innate immune functions of saliva in interactions with S. mutan

245 a single salivary constituent in the innate immune functions of saliva.

246 his review, we consider the inflammatory and immune functions of VSMCs and how they may lead to media

247 tients who survive sepsis display suppressed immune functions, often manifested as an increased susce

248 enomic regions that contain genes related to immune function or cancer risk in humans that exhibit co

249 enes encoding protein products that regulate immune function or cell adhesion and tumor cell metastas

250 ibility to sepsis might be explained by male immune function or increased systemic burden from higher

251 ognized by differences in marker expression, immune function, or tissue of residency.

252 and exit the circulation to carry out innate immune functions, or undergo rapid apoptosis and macroph

253 s not associated with any of our measures of immune function, perhaps suggesting immunological impair

254 utative mechanisms by which LAP may regulate immune function, perhaps through the metabolic reprogram

255 of treatment on body condition, haematology, immune function, physiological stress and oxidative stat

256 r surgery which could be due to ranging from immune function preservation to direct molecular mechani

257 to modification of infant formula to improve immune function, reduce inflammation and prevent conditi

258 Importantly, blockade of type I IFN improved immune function, reduced the HIV reservoir, and caused a

259 Differences were seen also in metabolism and immune function related gene expression.

260 mechanisms, however, by which light affects immune function remain unclear.

261 apidly diversified in teleost fish but their immune functions remain unclear.

262 ge-like Anchor (LRBA) is a PBW protein whose immune function remains elusive.

263 ies examining the roles of mTOR signaling in immune function revealed critical roles for mTOR in regu

264 associations with RNA regulatory processes, immune function, stem cell maintenance and binding sites

265 An individual's immune function, susceptibility to infection, and respon

266 Brain ischemia inhibits immune function systemically, with resulting infectious

267 The discovery of thymus immune function, T cells, and immune surveillance bore t

268 practice (control group; n = 102) or serial immune function testing (interventional group; n = 100)

269 Immune function testing provided additional data which h

270 fic Abeta hydrolysis appears to be an innate immune function that could be applied for therapeutic Ab

271 viduals might lead to significant changes in immune function that have thus far not been appreciated.

272 N has transgenerational effects on endocrine-immune function that may be mediated by global alteratio

273 lts identify ERAP1 as a modifier to leverage immune functions that may improve the efficacy of NK cel

274 and implicated in leukocyte inflammatory and immune functions, the roles of alphaXbeta2 remain largel

275 ay decrease parasite performance or increase immune function, thereby reducing infection risk or the

276 Beyond classical immune functions, they have been shown to be important f

277 tegy for harnessing biomaterials to polarize immune function through controlled delivery of metabolic

278 Mitochondria contribute to macrophage immune function through the generation of reactive oxyge

279 Dysregulated activation of leukocyte innate immune functions thus plays a role in pathological throm

280 t biological effects of social inequality on immune function, thus improving our understanding of soc

281 plication permits the preservation of potent immune functions, thus preventing HIV-2 disease progress

282 nsequences on diverse processes ranging from immune function to stress responses.

283 F. tularensis to modulate macrophage innate immune functions to create an environment permissive for

284 de control of CLL with further impairment of immune function, to the new agents targeting CLL B-cell

285 ications in homeostasis, osteoclastogenesis, immune functions, tumor metastasis and infections such a

286 n are associated with nutritional status and immune function using longitudinal data spanning 10 year

287 Based on immune function values, tacrolimus doses were reduced 25

288 Immune functions vary over the course of the day, but it

289 ocorticoid hormone, mediates development and immune function via splenocyte immunohistochemistry anal

290 rmine whether their effects on cell-mediated immune function were a contributing factor.

291 tored for diseases, and immune phenotype and immune function were evaluated by using flow cytometry,

292 s involved in DNA repair and antioxidant and immune functions were restored after the dietary-zinc in

293 embrane proteins, many without characterized immune functions, were downregulated during HIV infectio

294 teratocytes secrete products that alter host immune functions while also producing anti-microbial pep

295 okine signaling and plays important roles in immune function, while abnormal JAK1 activity has been l

296 dicine that can take advantage of the body's immune functions will increasingly become clinically rel

297 Declining immune function with age is associated with reduced lymp

298 rom donor, host, and third party showed good immune function with rejection of third-party grafts fro

299 infection had discordant effects to restore immune function without reducing arterial inflammation.

300 PD-L1 interaction to enhance T cell-mediated immune function, yet the effectiveness of anti-PD-L1/PD-