ライフサイエンスコーパス: immune memory

1 nteractions in primary T cell activation and immune memory.

2 in newborns and elicits protective antiviral immune memory.

3 es and its effect on vaccine efficacy and on immune memory.

4 effector cells and long-lived sentinels for immune memory.

5 DNA methylation, we propose an analogy with immune memory.

6 ned fashion but eventually inducing systemic immune memory.

7 establishment of tumor-specific and durable immune memory.

8 nal characteristics, including properties of immune memory.

9 sessed the ability of 1 or 2 doses to induce immune memory.

10 ibodies to encountered antigens and generate immune memory.

11 orous restimulation potential, a hallmark of immune memory.

12 germinal centre (GC) response and diminished immune memory.

13 pite having reduced fitness due to long-term immune memory.

14 nefits of Rapa treatment as means to improve immune memory.

15 ector functions and limits the generation of immune memory.

16 to secondary stimulation, and form long-term immune memory.

17 nd, consequently, impairs the development of immune memory.

18 xcessive) pathology and that elicit specific immune memory.

19 adapted (ca) backbone that induced long-term immune memory.

20 as necessary and sufficient to confer innate immune memory.

21 itumor response but still preserve antitumor immune memory.

22 sponse to PnCRM7 but does not interfere with immune memory.

23 wever, suggest an essential role for IL-2 in immune memory.

24 ve immunity in malaria may be dependent upon immune memory.

25 acity of knockout mice to develop protective immune memory.

26 evelopment of both humoral and cell-mediated immune memory.

27 past infections and a reservoir of potential immune memory [5].

28 mphasize the lung as a complex repository of immune memory after local infection.

29 Immune memory after smallpox vaccination (DryVax) is a v

30 marker for predicting reduced virus-specific immune memory after transcutaneous infection with a live

31 r, this involves the risk of autoimmunity if immune memory against host DNA is mistakenly acquired.

32 odeficient athymic mice, leading to specific immune memory against the tumor.

33 to enhance adaptive immunity and protective immune memory against viral infection.

34 o be mediated by mechanisms including innate immune memory (also known as "trained immunity") and cro

35 esponse, a finding that has implications for immune memory and autoimmunity.

36 ted robust serum antibody and CD4 Th1-biased immune memory and conferred protection against pneumococ

37 e markers closely associated with protective immune memory and could help to define a rational strate

38 low potency, inability to generate long-term immune memory and decreased activities against tumour-ce

39 ice and humans, at the dose shown to improve immune memory and extend lifespan.

40 + T cells helps to explain the phenomenon of immune memory and facilitates the design of effective th

41 osomal HAV vaccine is sufficient to activate immune memory and may provide long-term protection.

42 in control of tumor growth, establishment of immune memory and protection against tumors bearing anti

43 vaccines, and of antimicrobial therapies on immune memory and reconstitution after lymphocyte deplet

44 Moreover, because we capture adaptive immune memory and the impact of transplantation, this mo

45 the rate of cell turnover on the duration of immune memory and the maintenance of the immune repertoi

46 evealed functions for NK cells in long-lived immune memory and the regulation of adaptive immune resp

47 titumor immune activity as well as antitumor immune memory and therefore might have an impact against

48 he mechanisms involved in the development of immune memory and those conditioning Type I and CTL resp

49 imizing CD8(+) T-cell immunity, facilitating immune memory, and preventing tolerance.

50 Indeed, reports showing alternative forms of immune memory are accumulating in invertebrates.

51 t infection but the underlying mechanisms of immune memory are unclear.

52 ibody levels, and hepatitis B virus-specific immune memory, as evaluated with T-cell proliferation as

53 tep in the generation of long-lived adaptive immune memory at body surfaces.

54 ications for our understanding of protective immune memory at epithelial interfaces with the environm

55 The presence of immune memory at pathogen-entry sites is a prerequisite

56 administration in young adults and explored immune memory by measuring antibody avidity.

57 IL-15 thus seems to contribute to enhanced immune memory by selectively propagating memory T cells

58 Immune memory cells are poised to rapidly expand and ela

59 ng a repeat infection, dengue virus-specific immune memory cells are reactivated and large amounts of

60 Adoptive transfer of TLR7(+/+) LCMV immune memory cells that enhanced clearance of persisten

61 We hypothesized that innate immune memory contributes to the protective host defense

62 However, differential mucosal and systemic immune memory could be difficult to induce because of re

63 these various processes to the longevity of immune memory (defined as the rate of decline of the pop

64 Therapies targeted at reversing this immune memory depletion warrant further investigation.

65 ted changes and it is becoming apparent that immune memory exhibits significant defects as a result o

66 s specific to S. aureus are common, implying immune memory formation and suggesting a large pool of S

67 Although immune memory generated during youth functions well into

68 Immune memory has traditionally been the domain of the a

69 ections; yet, the role of dietary protein in immune memory homeostasis remains poorly understood.

70 A new study demonstrates that innate immune memory in Drosophila embryonic macrophages can al

71 and lymph nodes, but recently the concept of immune memory in peripheral tissues mediated by resident

72 This could pose a risk to the development of immune memory in persons previously infected with or vac

73 ents investigating the possible existence of immune memory in sponges indicate that faster second set

74 Immune memory is a central feature of the mammalian adap

75 he factors contributing to the generation of immune memory is important for rational vaccine design.

76 with concurrent inhibition of donor-specific immune memory is likely to be involved.

77 rrent understanding of the cellular basis of immune memory is reviewed and the relative contributions

78 Innate immune memory is the phenomenon whereby innate immune ce

79 While infection is associated with immune memory, little is known regarding the role of the

80 By preventing measles-associated immune memory loss, vaccination protects polymicrobial h

81 These findings suggest that innate immune memory, mediated by specific cellular and molecul

82 The extent to which this is a consequence of immune memory of infection history or prevalent diversit

83 ve to be optimised to boost the efficacy and immune memory of protection against HIV-1 in the clinica

84 ults indicate that the various components of immune memory operate together to provide optimal protec

85 BCG- but not LCMV-immune memory phenotype CD4 T cells preferentially produ

86 Each cluster had immune memory profiles that differed in magnitude and qu

87 Effective immune memory relies, in part, on the maintenance of the

88 that the persistence of an immune response (immune memory) requires the density of persistent antige

89 Recent developments in the field of immune memory research and the accumulating literature o

90 implicated in the generation of a protective immune memory response following priming by the injectio

91 ey innate mechanism in the regulation of the immune memory response to allergens.

92 his was not solely the result of a classical immune memory response, but rather involved local persis

93 hile primary infection generates an adaptive immune memory response, stem cell transplantation disrup

94 ss and-through challenge vaccination-humoral immune memory response.

95 and second transplant may be a stimulus for immune memory responses and increased risk of alloimmune

96 an initiate and propagate rapid and vigorous immune memory responses.

97 vaccinated individuals develop and that this immune memory signature is different from that seen in s

98 ignificant toxicity and 83% of survivors had immune memory specific for E0771 cells.

99 persisted for at least 6 years, and induced immune memory, suggesting possible protection against HP

100 specific CD8(+) cytotoxic T lymphocytes with immune memory than IFA-emulsifying vaccines.

101 The A(H7N9) pLAIV induces strong immune memory that can be demonstrated by exposure to su

102 s are able to help the immune system develop immune memory that can have long-lasting, tumor-specific

103 CD8+ T lymphocytes confers a key feature of immune memory: the capacity for autonomous secondary exp

104 propriate effector functions and maintaining immune memory, they also can cause autoimmunity or neopl

105 ope M1(58-66) can be an instructive model of immune memory to a nonevolving epitope of a frequently e

106 d qualitative approach to comparing adaptive immune memory to influenza 1 year after mild or severe i

107 it the stem cell characteristics of cellular immune memory to promote long-term viral persistence.

108 are active and dynamic, capable of inducing immune memory to propagate a successful rebalancing of t

109 ed target cells, and may be involved in host immune memory to this parasite.

110 nomenon termed "trained immunity" or "innate immune memory." Trained immunity is orchestrated by epig

111 reports of Thy1(+) NK cells contributing to immune memory, we analyzed their role in secondary prote

112 inst HIV-1 acquisition, but the efficacy and immune memory were inadequate.

113 rs and development of long-lasting antitumor immune memory, which was primarily attributed to the act

114 cells, then, for a wide range of parameters, immune memory will be long-lived in the absence of persi

115 e) is greater than this threshold value then immune memory will be relatively short lived.