ライフサイエンスコーパス: immune response(|s) (to|against)

1 ection continues to provide insight into the immune response against a virus with an extraordinary mu

2 superinduction is required for the inducible immune response to a bacterial pathogen.

3 immunotherapies; and (iii) personalizing an immune response to a patient's tumor.

4 immunoglobulin concentrations and an intact immune response to a T-cell-independent antigen, their r

5 d and personalized assessment of the patient immune response to a tumour.

6 e ability of the brain to initiate an innate immune response to a virus, which was directly injected

7 the mechanisms that negatively regulate host immune responses to a fungal infection.

8 ells, murine NK cells also mediated adaptive immune responses to a secondary challenge with specific

9 cus on new literature regarding allergic and immune responses to a variety of environmental factors,

10 that target PD-1-PD-L1 to enhance protective immune responses to A. fumigatus infections.

11 different filoviruses may require different immune responses to achieve immunity.

12 ic CD8+ T cells are key players for adaptive immune responses against acute infections with retroviru

13 rly gammadelta T cells) in the host cellular immune response against AIM and CAEBV.

14 Allergic immune responses to airborne allergens likely involve 2

15 We now characterize the cellular immune response to all 7 PIV3-encoded antigens in 17 hea

16 rgic airway disease (AAD) caused by aberrant immune responses to allergens.

17 -fat diet (HFD)-induced obesity and assessed immune responses to allogeneic stimulation in vitro, all

18 Immune responses to allografts represent a major barrier

19 and FcRn knockout mice were able to mount an immune response against anti-TNF-alpha Abs, suggesting t

20 n, changes in the protective efficacy of the immune response to B. burgdorferi surface antigens were

21 More research is needed to understand the immune response to B. pertussis infection in children va

22 into adult recipients impaired their innate immune response to B. pertussis infection.

23 Enhanced innate immune response to B. pertussis was characterized by inc

24 e-suppressive properties and suppress innate immune responses against B. pertussis infection.

25 inhibit potentially protective cell mediated immune responses against B. pseudomallei, but may also m

26 re an effective way to create a long-lasting immune response against bacteria.

27 in the lung or on the intrapulmonary innate immune response to bacteria or lipopolysaccharide, as as

28 al arsenic has little effect on local airway immune responses to bacteria but compromises respiratory

29 l mechanism by which viruses alter normal FM immune responses to bacteria, potentially giving rise to

30 mportant roles in T cell-independent humoral immune responses against blood-borne pathogens.

31 based vaccine against CDV induces protective immune responses against both pathogens.

32 novel platform for studying the human innate immune response to C. burnetii.

33 nds in the colon and impaired mucosal innate immune responses against C. rodentium infection, manifes

34 Reactogenicity and immune responses to cAd3-EBO vaccine were dose-dependent

35 cancer antigens to DCs in order to cause an immune response against cancer is an emerging area of na

36 novel strategies to elicit a more integrated immune response against cancer.

37 ne checkpoint inhibitors), which enhance the immune response to cancer cells, improve clinical outcom

38 cular and histological traits shape the host immune response to cancer.

39 stion and is a therapeutic target to enhance immune responses against cancer and chronic infections.

40 modulation and the functions of IgE-mediated immune responses against cancer, to derive novel insight

41 concentrate use, without detectable cellular immune responses against capsids.

42 We sought to characterize immune responses to casein in children with FPIES caused

43 se results demonstrate the complex nature of immune response to checkpoint blockade and the compellin

44 ight into the role of Vdelta2 T cells in the immune response to chronic malaria.

45 sed on a lack of methylation and initiate an immune response to clear the infection.

46 sease (CD) is associated with a dysregulated immune response to commensal micro-organisms in the inte

47 Dendritic cells (DCs) initiate immune responses to common aeroallergens, and ADAM10 has

48 mmunodominance (ID) defines the hierarchical immune response to competing antigens in complex immunog

49 receptors (PRRs) that initiate quantitative immune responses to control host-microbial load, whereas

50 ion in testis and sperm autoimmunity and the immune responses to CTA in male cancer patients.

51 How Drosophila mounts differential immune responses to dead and live Gram-negative bacteria

52 ral or microbial DNA triggers cell-intrinsic immune responses to defend against infections, whereas a

53 s broadening our understanding of the innate immune response to dengue virus infection.

54 5 as critical players in innate and adaptive immune responses against DENV, and targeting these recep

55 less likely to develop long-lasting humoral immune responses to DENV, as measured in healthy annual

56 capsular antibodies in the infants and their immune response to diphtheria toxoid and pneumococcal va

57 h a placebo group, and did not affect infant immune responses to diphtheria toxoid and pneumococcal v

58 ific cell surfaces, thus allowing the innate immune response to discriminate between self and foreign

59 tools can help improve our understanding of immune responses to disease and aid in the design and en

60 M) injection has the potential to tailor the immune response to DNA vaccination.

61 Humoral immune responses against donor antigens are important de

62 erstanding of the factors that determine the immune response to each vaccine antigen.

63 an population points to both forms of innate immune response to EBV having benefit for human survival

64 and discuss our current understanding of the immune response to EBV in healthy, immunocompetent indiv

65 is a comparative analysis of the host innate immune response to either MARV or EBOV infection in bat

66 No interference in the immune responses to either vaccine was observed when the

67 tor of IFN genes (STING) agonists stimulates immune responses to eliminate tumor cells that are not r

68 ach other within and across these scales for immune responses to emerge, and how aberrant regulation

69 we demonstrate that MDA5 is crucial for the immune response to enteric rotavirus infection, a propos

70 ates that CCR7 is required to mount a robust immune response against enteropathogenic Y. pseudotuberc

71 ic lung disease resulting from inappropriate immune responses to environmental antigens.

72 Overcoming the immune response to establish durable immune tolerance in

73 luding released factors, which modulate host immune responses to establish a harsh environment for cl

74 equired for the full activation of an innate immune response to exogenous DNA and DNA viruses.

75 odels can be used to show efficacy, antidrug immune responses to experimental protein-based therapeut

76 Little is known about the immune response to F. hepatica following natural exposur

77 antagonists that counteract the host innate immune response to facilitate efficient viral replicatio

78 m tuberculosis is known to modulate the host immune responses to facilitate its persistence inside th

79 tudy was aimed at characterization of innate immune responses to filoviruses and the role of filoviru

80 ids while maintaining a prompt and efficient immune response to foreign nucleic acids derived from in

81 hat play critical roles in initiating innate immune responses against foreign pathogens and other typ

82 al infection, and we characterized the aphid immune response to fungi by measuring immune cell concen

83 s problem with this therapy is the patient's immune response to FVIII, because of a lack of tolerance

84 of IL-17A in the development of a protective immune response against Giardia.

85 estinal inflammatory disorder mediated by an immune response to gluten peptides in genetically suscep

86 liac disease (CD) patients mount an abnormal immune response to gluten.

87 me the inherent T cell-independent nature of immune responses against glycans.

88 no adjuvant has been shown to potentiate the immune response to glycoconjugate vaccines in humans, we

89 of IBD is partly attributed to a deregulated immune response to gut microbiome dysbiosis.

90 aid in deciphering the role of MAIT cells in immune responses to HBV.

91 hance the breadth and potency of the humoral immune response against HCV.

92 ulation in APCs in order to establish potent immune responses against HCV.

93 nary perspective, subjects with an effective immune response against helminths can be more susceptibl

94 arphi) play a critical role in regulation of immune responses to hepatic infection and regeneration o

95 phagocytosis and produced durable antitumour immune responses against HER2-expressing tumours.

96 d cytokines elevated in subjects with a good immune response against HIV and defined potential mechan

97 a single class II MHC-peptide complex to the immune response against HIV-1 infection.

98 a single class II MHC-peptide complex to the immune response against HIV-1 infections.

99 -cell counts may reflect disturbances in the immune response to HIV-1 in the CNS.

100 can participate in the innate cell-mediated immune response to HIV-1.

101 cells plays a role in the effective adaptive immune response to HIV.

102 to decrease viral dissemination and improve immune responses against HIV-1.IMPORTANCE DCs play a key

103 ANCE DCs play a key role in the induction of immune responses against HIV.

104 that are responsible for sustaining humoral immune responses against HIV.

105 luding the possible contribution of adaptive immune responses to HIV-associated neurocognitive disord

106 o treating allergic asthma via regulation of immune response to house dust mite.

107 x play an important role during an intrinsic immune response to HSV-1 and are also degraded or inacti

108 own to play a variety of roles in modulating immune responses to HSV and other pathogens, and there i

109 es, and identifies more pathways relevant to immune-response to human influenza infection than the co

110 In 430 participants, humoral immune response to HZ/su was noninferior in HZ-PreVac co

111 ve previously been described, but the global immune response to in vivo gluten exposure in CD has not

112 ed a pivotal role in dissecting the mosquito immune response against infection.

113 OCS1 in CD11c(+) cells skewed the balance of immune response to infection by increasing innate respon

114 th adjuvant therapies aimed at modifying the immune response to infection holding the greatest potent

115 ncing understanding of the dysregulated host immune response to infection in sepsis.

116 The inducible innate immune response to infection requires a concerted proces

117 However, because DON inhibited the immune response to infection, clearance of the virus fro

118 enes) in MDD were significantly enriched for immune response to infection, were concentrated in a mod

119 threatening condition caused by an excessive immune response to infection.

120 ndothelium dysfunction and modulate the host immune response to infection.

121 or gestational maternal infection and innate immune responses to infection in the pathogenesis of at

122 oordination of the lifesaving or detrimental immune response against infections.

123 ory processes and are involved in protective immune responses against infections.

124 tory receptors play a key role in regulating immune responses to infections.

125 try offer expanded potential for deciphering immune responses to infectious diseases and to vaccines.

126 erferon expression, resulting in an improved immune response to influenza infection.

127 One of the major components of the immune response to influenza is the induction of the typ

128 colonized with S aureus exhibited a reduced immune response to influenza vaccination compared with n

129 in pursuing an extended project on the human immune response to influenza vaccines.The result shows t

130 our recently developed mAbs for studying the immune response to influenza virus infection and vaccina

131 present a rule-based model of the intrahost immune response to influenza virus infection.

132 hat progestins significantly affect adaptive immune responses to influenza A virus infection, with th

133 a negative regulator in inducing protective immune responses to influenza vaccination.

134 Immune responses to influenza vaccines decline with age,

135 Most humoral immune responses to influenza virus target the hemagglut

136 B cells are a major part of the adaptive immune response to inhaled HDM allergen, particularly wh

137 diabetic mice results from a delay in innate immune response to inhaled Mycobacterium tuberculosis, l

138 he aim of this study was to characterize the immune response against intrabone marrow (BM-Tx) or intr

139 dality capable of imaging the host antitumor immune response against intracranial tumors.

140 ified in bacteria and archaea as an adaptive immune response to invading genetic material, has been e

141 important not only for instigation of innate immune responses to invading pathogens but also for init

142 ar patterns and play crucial roles in innate immune responses to invading pathogens.

143 termine the targets of the host's CRISPR-Cas immune response against its invaders.

144 at polyomavirus reactivation associates with immune responses to kidney-specific self-antigens that m

145 estigate the protective mechanisms of innate immune responses to KyA, KyA-immunized mice were challen

146 f several aspects of the innate and cellular immune responses to Lassa virus.

147 ggests that they may play a critical role in immune responses to Leishmania.

148 DNA reservoirs reflects the effectiveness of immune responses against lentiviruses.

149 ew opportunities for boosting the macrophage immune response to limit infection.

150 tion, in conscious rats, controls the innate immune response to lipopolysaccharide attenuating the pl

151 Peak immune response to lipopolysaccharide treatment in mice

152 Persistent hypercholesterolemia leads to immune responses against lipoprotein particles that driv

153 iesis under steady state and dampened innate immune responses against Listeria monocytogenes infectio

154 ental autoimmune encephalitis, and defective immune responses to lymphocytic choriomeningitis virus i

155 ma and IL-17A production during the cellular immune response to M. tuberculosis.

156 the range of antigenic targets for adaptive immune responses to M. tuberculosis and may help to info

157 ses of other candidate genes involved in the immune response to malaria have not been able to account

158 thways that may explain the uncharacteristic immune response to malaria.

159 and thus plays a critical role in the innate immune response to malignant transformation.

160 Immune responses to Marburg virus (MARV), however, remai

161 Thus, EBI3 dampens the immune response against MCMV infection, resulting in pro

162 xtracellular traps (NETS) and impacts on the immune response to melanoma metastases.

163 By understanding the immune response to MERS-CoV we can develop targeted ther

164 aining the MERS-CoV S1 protein induce potent immune responses against MERS-CoV and RABV.

165 40 signaling pathway, which could impact the immune response to metastatic cells.

166 reveals neuroinflammation associated with an immune response against MHC-mismatched grafted cells.

167 e liver failure (ALF) have defects in innate immune responses to microbes (immune paresis) and are su

168 and implicate mucosal factors and the innate immune response to microbial exposure in Behcet's diseas

169 ry bowel disease (IBD) that functions in the immune response against microorganisms.

170 ein family mediates a flexible and effective immune response to multiple foreign cells.

171 e of TOLLIP variation on innate and adaptive immune responses to mycobacteria and susceptibility to t

172 perience tuberculosis relapse have different immune responses to mycobacteria in vitro than patients

173 rophages play an essential role in the early immune response to Mycobacterium tuberculosis and are th

174 An effective immune response to Mycobacterium tuberculosis most likel

175 Thus, augmenting host immune responses against Mycobacterium tuberculosis by h

176 Nonhuman primates can be used to study host immune responses to Mycobacterium tuberculosis Mauritian

177 s of labile CPS induce a specific protective immune response against native CPS using S. pneumoniae s

178 Here, we mined the human immune response to natural EBOV infection and identified

179 We used an in vivo model to study the immune response to necrotic liver injury and found that

180 In this study, we investigate early immune responses to neonatal porcine islet (NPI) xenogra

181 oint inhibition may favor the development of immune responses against neuronal antigens, leading to a

182 ts suggest an association between a maternal immune response to NLGN4Y and subsequent sexual orientat

183 ditional mechanism whereby Tregs control the immune response to non-self-antigens.

184 the host immune response to non-VlsE antigens became sufficiently

185 Cellular immune responses against NS5 were also elicited, as evid

186 iew the current evidence regarding the human immune response to OIT, explore possible mechanisms, and

187 al OC cell fusion without affecting adaptive immune responses to oral bacteria.

188 raft and the recipient and its effect on the immune response to organ transplantation.

189 understanding of the effect of aging and the immune response to organ transplantation.

190 elta2 T cells are activated during the early immune response against P. falciparum infection, we inve

191 data reveal the importance of PRR2 in plant immune responses against P. syringae and suggest a novel

192 nd the impact of female sex hormones on host immune responses to P. aeruginosa We used wild-type and

193 of IL-25, a critical initiator of the type 2 immune response to parasite infection.

194 cells, basophils, and IgE can contribute to immune responses to parasites; however, the relative lev

195 es (M2) have an important function in innate immune responses to parasitic helminths, and emerging ev

196 ions as a checkpoint regulator of the innate immune response to pathogen challenge.

197 Plants have complex and adaptive innate immune responses against pathogen infections.

198 and Nod2 play important roles in the innate immune response to pathogenic microbes, but mounting dat

199 diversification that can be selected in the immune response against pathogens and exploited for B ce

200 Immune response against pathogens is a tightly regulated

201 kines that are essential for a potent innate immune response against pathogens.

202 amma is the central mediator of the adaptive immune response to pathogens, it has been shown to be in

203 ophages play a crucial rule in orchestrating immune responses against pathogens and foreign materials

204 up 2 innate lymphoid cells (ILC-2s) regulate immune responses to pathogens and maintain tissue homeos

205 e receptors (TLRs) play an important role in immune responses to pathogens by transducing signals in

206 LA-DRB3 molecule was found in addition to an immune response against patient's mismatched HLA-DPB1 mo

207 We determined the immune responses to PCV13 before and at 1, 12, and 24 mo

208 ing methods to predict disease states or the immune response to perturbations.

209 al antibodies to pertussis can hamper infant immune responses to pertussis vaccines.

210 Characterizing the immune response to pneumococcal proteins is critical in

211 , 98.0%, and 98.0% of fIPV recipients had an immune response to poliovirus types 1, 2, and 3, respect

212 otential differences between human and mouse immune responses to polytrauma.

213 rts have recently focused on enabling strong immune responses to poorly immunogenic antigens, via dis

214 that inflammation be redefined as the innate immune response to potentially harmful stimuli such as p

215 e TGN is critical for effective pre-invasive immune responses against powdery mildews.

216 ion, potentially via maternal neuroendocrine-immune responses to prenatal stressors, which adversely

217 as a potential strategy to augment the host immune response to prevent serious bacterial infections,

218 focused on cancer vaccines to reprogram the immune response to prevent, detect, and reject premalign

219 ngivalis is able to invade and modulate host-immune response to promote its survival.

220 e different components of allergen-triggered immune responses to promote and maintain tolerance.

221 determines the functional consequences of an immune response to pulmonary fungal infection that can u

222 or detailed investigation of T cell-mediated immune responses to PVM in a variety of genetically modi

223 the cat flea (Ctenocephalides felis) innate immune response to R. typhi Initially, we determined tha

224 fety profile and property of inducing potent immune responses against recombinant (r) antigens.

225 is critical to the initiation of the innate immune response to RNA virus infection.

226 ssed a possible contribution of basophils in immune responses to S. venezuelensis By immunohistochemi

227 uited monocytes to regulate a maximal innate immune response to Salmonella infection, allowing a sust

228 endent developmental differences in adaptive immune responses to self-antigens independent of externa

229 To evaluate their impact on immune responses to sequential IAV infections, adult fem

230 nts to promote robust and durable protective immune responses against SIV in nonhuman primates.

231 During the immune response to so-called "thymus-dependent Ags," act

232 ecreases the incidence of colds and improves immune responses to some pathogens.

233 y design ST toxoids that elicit neutralizing immune responses against ST with minimal risk of immunol

234 The immune response to Staphylococcus aureus infection in sk

235 cles enables noninvasive detection of innate immune responses to stem cell transplants with magnetic

236 ytol enables noninvasive detection of innate immune responses to stem cell transplants with MR imagin

237 the corneal microenvironment that influence immune responses to subsequent corneal infection or trau

238 R-155 specifically within T cells during the immune response to syngeneic tumors.

239 ne landscape of TME and subsequently amplify immune response to systemic antitumor immunity.

240 ew presents our current understanding of the immune response to TBI in a chronological and compartmen

241 fects hepatocytes, but the mechanisms of the immune response against the virus and how it affects dis

242 hanges in salamander cells suggest an innate immune response to the alga, with potential attenuation

243 complement pathway and directing the innate immune response to the distressed renal tubule.

244 underlying pathophysiology, representing the immune response to the JC virus to a variable extend.

245 Our model incorporates the data on the human immune response to the parasite, and AL's pharmacokineti

246 Thus, we characterized the cellular immune response to the virus and identified F, N, M2-1,

247 in these tissues as well as on the maternal immune response to the virus.

248 aying heterologous antigens generated better immune responses against the antigen and different IgG s

249 Recent studies have shown that immune responses against the cell-traversal protein for

250 f IgG1 levels vs alum) and the cell-mediated immune responses against the encapsulated antigen (ovalb

251 nce prior immunity to a scaffold may inhibit immune responses to the antigen-scaffold combination.

252 ore recent wild-type strain, indicating that immune responses to the more conserved fusion protein co

253 ations between polyomavirus reactivation and immune responses to the self-antigens fibronectin (FN) a

254 growth and to convert and suppress adaptive immune responses to the tumor.

255 ll viruses strategically alter the antiviral immune response to their benefit.

256 fused to a wide range of antigens, enhancing immune responses against them.

257 th the pathogen in vitro and in vivo and the immune response to these bacteria.

258 immunity, we wanted to compare the cellular immune response to this challenge strain to the response

259 that corticosteroids potently attenuate the immune response to this pathogen.

260 to review what is known (and unknown) about immune responses to this fascinating virus.

261 fashion that potently stimulates endogenous immune responses against those antigens.

262 ecular mechanisms that coordinate the innate immune response to tissue damage and cell death in the l

263 plicated as mechanisms to suppress dangerous immune responses to tissue-restricted self-Ags.

264 anding of the role of DAMPs in directing the immune response to transplantation has suggested novel a

265 ively assess the ultra-early, within 1-hour, immune response to trauma and perform an exploratory ana

266 lmost all studies that have investigated the immune response to trauma have analysed blood samples ac

267 ighted the dynamic and complex nature of the immune response to trauma, with immune alterations consi

268 tibiotic-free strategy for tuning the innate immune response to treat methicillin-resistant S. aureus

269 inogenesis through suppression of the hosts' immune response to tumor.

270 CD8(+) T lymphocytes mediate potent immune responses against tumor, but the role of human CD

271 ful adjuvant activity for enhancing adaptive immune responses to tumor antigens released by radiother

272 reaction, it concomitantly activates innate immune responses to tumor expansion.

273 BACKGROUND & AIMS: Agents that induce an immune response against tumors by altering T-cell regula

274 oncogene-targeted therapies may restore the immune response against tumors.

275 rowth and negatively affecting the patient's immune response to tumors.

276 s, mechanisms of their synergy with adaptive immune responses against tumors, and discuss recent stud

277 lls and may contribute to the attenuation of immune responses to tumors.

278 as a consequence of both adaptive and innate immune responses to undigested gliadin peptides.

279 nths cause chronic infections and affect the immune response to unrelated inflammatory diseases.

280 One's history of infections can affect the immune response to unrelated pathogens and influence dis

281 es to sedation were strongly correlated with immune responses to vaccination.

282 cal factors that mediate innate and adaptive immune response to vaccines.

283 o those of VACV, implying that the decreased immune response to vDeltaK1L infection, not virus replic

284 tion of host proteins involved in the innate immune response to viral infection.

285 ociated protein 5 (MDA5) mediates the innate immune response to viral infection.

286 ch is a central component of the host innate immune response to viral infection.

287 ptors that recognize self-MHC class I during immune response to viral infections is unknown.

288 surviving animals at two sites vital to the immune response to viral infections, bone marrow and lym

289 e added benefit of inducing a cross-reactive immune response to viral strains not found in the vaccin

290 as a potent target through which the innate immune response to viral vectors, and potentially other

291 epsilon to propel type I IFN-mediated innate immune responses against viral infection.

292 in the orchestration of mucosal and systemic immune responses against viral pathogens in vertebrates.

293 Protective immune responses to viral infection are initiated by inn

294 uding the regulation of apoptosis and innate immune responses to viral infection, have been proposed

295 activity that can alter innate and adaptive immune responses to viral infection.

296 Gs are emerging as a component of the innate immune response to virus infection, and modulation of SG

297 rly understood, players in the host's innate immune response to virus infection.

298 The host immune responses to ZIKV infection have not been fully e

299 ice mount cell-mediated and humoral adaptive immune responses to ZIKV, these responses were not requi

300 We compared the immune responses to zoster vaccine in young and older to