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1 virus, even in patients who were previously immunocompetent.
2 r vaccine to indicated adults while they are immunocompetent.
6 V-GPC was unable to establish persistence in immunocompetent adult mice, which prevented its use for
8 t of antifungal prevention in critically ill immunocompetent adult patients on mortality and subseque
10 (VZV) contained in Zostavax in a 68-year-old immunocompetent adult with strong evidence of prior wild
12 st because of its ability to persist in most immunocompetent adults and because of the lack of a prot
14 s, together with gene expression profiles in immunocompetent adults experiencing a severe primary HCM
15 ria of >10 nucleated cells/mul in the CSF of immunocompetent adults for viral CSF NAAT assays would i
16 Emory University that enrolled non-pregnant, immunocompetent adults from Atlanta, GA, USA, who were a
17 A total of 115 cytomegalovirus seropositive, immunocompetent adults with critical illness were enroll
20 ized specific immunity in 207 nonsymptomatic immunocompetent and 132 immunocompromised individuals in
21 chopulmonary aspergillosis (ABPA) in overtly immunocompetent and atopic individuals, respectively.
22 The dominant mechanism of TA-GVHD in both immunocompetent and compromised hosts is exposure to via
23 ectrum of infection-related diseases in both immunocompetent and immunocompromised hosts, ranging fro
25 dy, we examined mucosal infection in several immunocompetent and immunocompromised mouse strains.
28 bpA/B-deficient spirochetes occurred in both immunocompetent and immunodeficient mice in a manner ind
30 titration studies evaluating these islets in immunocompetent and nonobese diabetic mouse models are u
31 gether, these data suggest that BCV protects immunocompetent and partially T cell-reconstituted immun
32 . burgdorferi to establish infection in both immunocompetent and SCID mice and has been proposed to f
33 ) of the persistently infected patients were immunocompetent, and 65% were symptomatic with relapsing
34 Geneva, Switzerland, enrolled non-pregnant, immunocompetent, and otherwise healthy adults aged 18-65
36 long-term glycemic correction of a diabetic, immunocompetent animal model using human SC-beta cells.
38 for the development of macaques and pigs as immunocompetent animal models to study HBV infection in
39 th an otherwise identical IgG in a syngeneic immunocompetent animal, and we identify TNFalpha/MCP-1 s
40 ate infection by the enteral route either in immunocompetent animals or in animals deficient in the i
46 e where Candida albicans infections occur in immunocompetent as well as immunosuppressed individuals.
48 ept inhibited MHC-I(high) melanoma growth in immunocompetent but not in immunodeficient (IFNgamma(-/-
50 to exhibit an early dissemination defect in immunocompetent, but not immunodeficient, mice, and the
51 mediated more potent antiglioma activity in immunocompetent C57BL/6 but not immunodeficient athymic
52 and IL-17 production by lung lymphocytes in immunocompetent C57BL/6 mice over time following infecti
53 ction in vitro in the presence of serum from immunocompetent C57BL/6 or immunocompromised mice lackin
56 now report that IV.3 induces anaphylaxis in immunocompetent CD32a-transgenic "FCGR2A" mice, along wi
60 Demodex folliculorum should be considered in immunocompetent children with rosacea or rosacea-like re
61 Neither the proportion of adult cases with immunocompetent comorbidities (relative risk ratio [RRR]
63 nse to monocrotaline challenge compared with immunocompetent controls despite daily imatinib administ
64 colon organoids we describe a broadly usable immunocompetent CRC model that recapitulates the entire
65 fungal prevention of systemic candidiasis in immunocompetent critically ill adults did not reduce mor
69 32 mg/mL of methylprednisolone for 7 days in immunocompetent flies led to increased mortality and a h
72 In breast carcinoma-bearing mice that were immunocompetent, GARP overexpression promoted Foxp3(+) T
76 mmune activation in DENV target organs of an immunocompetent host and supports the further developmen
77 vironment, which is quickly contained in the immunocompetent host but can cause lethal invasive asper
79 utant Braf(V600E) mouse melanoma cells in an immunocompetent host requires their production of prosta
80 ce (long-term antigen unresponsiveness in an immunocompetent host) presents the exciting prospect of
87 perficial and cutaneous fungal infections in immunocompetent hosts and invasive disease in immunocomp
88 morbidity and sometimes fatal infections in immunocompetent hosts and is thus an important pathogen
89 norovirus cell tropism in orally inoculated, immunocompetent hosts at the peak of acute infection and
90 neously growing syngeneic prostate tumors in immunocompetent hosts improved animal survival after sur
91 ion from engineered mouse cells grafted onto immunocompetent hosts increased insulin secretion and re
92 r of T cells from DLL1-treated tumor-bearing immunocompetent hosts into tumor-bearing SCID-NOD immuno
93 latency; however, long-term EBV infection in immunocompetent hosts is limited to B cells with a more
94 eria for deferring HSV PCR testing of CSF in immunocompetent hosts with normal CSF white blood cell a
95 sa elicits strong innate immune responses in immunocompetent hosts, and the resulting recruitment of
96 esumably was developed for interactions with immunocompetent hosts, in whom organism loads are substa
97 ment and inflammatory cytokine production in immunocompetent hosts, the impact of C. gattii infection
98 immunocompromised mice, it is controlled in immunocompetent hosts, where immune cells in combination
99 us that are key for disease establishment in immunocompetent hosts-alpha-hemolysin (Hla), iron-regula
111 resents a successful defense mechanism by an immunocompetent human host to eliminate VZV reactivation
112 ions of VZV-infected human brain from living immunocompetent human subjects are exceedingly rare.
114 hypoxia compared to the original tumours in immunocompetent humans, and hypoxia was reduced by adopt
115 IS) hosts, but an M2 predominant response in immunocompetent (IC) hosts following Pneumocystis carini
117 signaling motifs suppresses tumor growth in immunocompetent, immunocompromised, and PD-1-deficient t
118 characterized by adjectives such as immune, immunocompetent, immunosuppressed, immunocompromised, or
119 n earlier study, we reported infection of an immunocompetent individual with multiple strains of Aero
120 , clinically apparent cancers still arise in immunocompetent individuals in part as a consequence of
121 h tropism for B lymphocytes and infection in immunocompetent individuals is typically asymptomatic an
124 B19V DNA-positive serum samples from 222 immunocompetent individuals were analyzed for (1) viral
126 ngeal carcinomas and lymphomas developing in immunocompetent individuals, even though in these patien
127 imary infection is generally asymptomatic in immunocompetent individuals, HCMV is a significant cause
128 ng of the immune response to EBV in healthy, immunocompetent individuals, in transplant recipients, a
129 included case-control or cohort studies, in immunocompetent individuals, that calculated the odds ra
130 ive in controlling HSV-1 or -2 infections in immunocompetent individuals, their use in immunocompromi
141 ms involved during primary HCMV infection in immunocompetent individuals.IMPORTANCE HCMV-specific imm
143 of immune control, we sought an outbred and immunocompetent laboratory mouse strain in which persist
146 rain is able to rapidly germinate within the immunocompetent lung environment, inducing greater lung
147 he kinetics of long-circulating liposomes in immunocompetent mammary carcinoma-bearing FVB/n and BALB
149 emphigoid animal model featuring pruritus in immunocompetent, mature, and largely unmanipulated anima
151 mmunophenotype an orthotopic glioma model in immunocompetent mice after Myxoma virus (MYXV) administr
152 neutrophils, CCR2(+) monocytes, or both from immunocompetent mice and determined susceptibility to in
153 of spontaneous melanoma brain metastasis in immunocompetent mice and developed molecular tools for q
154 contemporary and historical ZIKV strains in immunocompetent mice and mice lacking components of the
155 ignant gliomas were established in syngeneic immunocompetent mice and then treated with dendritic cel
156 ificantly faster clearance than unvaccinated immunocompetent mice and unvaccinated CD4-depleted mice
157 of a murine norovirus inoculated orally into immunocompetent mice are macrophages, dendritic cells, B
159 of homologous B. burgdorferi to superinfect immunocompetent mice as opposed to heterologous strains.
160 d the luciferase transposon and repressor to immunocompetent mice by hydrodynamic injection, initial
161 o show that primary tumors can be modeled in immunocompetent mice by microinjecting CCR9-expressing c
162 SC)-derived hepatocyte-like cells (iPS-H) in immunocompetent mice by pre-engineering 3D cell co-aggre
163 this study was to explore the role of CG in immunocompetent mice challenged aerogenically with Mycob
165 F10 cells induced tumor growth inhibition in immunocompetent mice following a rechallenge with live c
166 These data suggest that ST-246 protects immunocompetent mice from lethality and reduces viral di
168 6-F10 melanoma growth in the rear footpad of immunocompetent mice induces marked B cell accumulation
169 nd adaptive responses previously observed in immunocompetent mice inoculated with trophic forms compa
170 urprisingly, after peripheral inoculation of immunocompetent mice on the day of birth, the first cell
171 that the host response to DENV infection in immunocompetent mice recapitulates transcriptional chang
173 addition, CD4 T cell epitope vaccination of immunocompetent mice reduced MCMV replication in the sam
174 la enterica serovar Typhimurium infection of immunocompetent mice results in acute followed by chroni
177 oculation into the uterine wall of pregnant, immunocompetent mice to evaluate transplacental transmis
179 describe a syngeneic orthotopic HCC model in immunocompetent mice with liver cirrhosis induced by car
180 arget for cancer immunotherapy by immunizing immunocompetent mice with Tem1 cDNA fused to the minimal
183 n metastasis models in immunocompromised and immunocompetent mice, and tested the fate and efficacy o
184 s increased during Pneumocystis infection in immunocompetent mice, IL-17A is not required for control
185 lthough M. tuberculosis persists in lungs of immunocompetent mice, M. bovis BCG is cleared, and clear
198 of the lower genital tract in heterozygous (immunocompetent) mice of the NU/J strain progressed to h
199 In this study we employed an orthotopic immunocompetent model of lung adenocarcinoma in which mu
202 erspecies transmission and establish a novel immunocompetent model system, we examined the ability of
205 In this issue of Blood, Lykken et al used an immunocompetent mouse model of B-cell lymphoma to discov
209 datasets and applied expression data from an immunocompetent mouse model of metastasis as an addition
210 vitro and in vivo in a clinically relevant, immunocompetent mouse model of pancreatic ductal adenoca
213 I:C and CpG with trastuzumab-like therapy in immunocompetent mouse models of ErbB2(+) breast cancer.
215 he context of anti-PD-1 therapy in two fully immunocompetent mouse models of lung adenocarcinoma.
219 best characterized MPS-I murine model is an immunocompetent mouse, we here developed a transplantati
220 FIST15 failed to establish tumors in vivo in immunocompetent murine hosts and could only form tumors
221 cites using fluid from human patients and an immunocompetent murine model (ID8) of EOC that mirrors h
222 d CAR T-cell function following BMT using an immunocompetent murine model of minor mismatched allogen
223 ient survival, and here we demonstrate in an immunocompetent murine model that colon tumors expressin
224 ative and prophylactic treatments in healthy immunocompetent, MyD88-deficient, lymphocyte-deficient,
228 thobunyavirus, has only been identified in 3 immunocompetent North American patients with acute neuro
229 Reports of HHV-6A or HHV-6B encephalitis in immunocompetent older children/adults are most likely du
230 ntigen receptor construct (chNKG2D) in fully immunocompetent orthotopic glioblastoma mouse models.
233 eously in living tumors and across a diverse immunocompetent patient population may provide a foundat
234 heter-associated bloodstream infection in an immunocompetent patient prior to heart transplantation.
237 y to help discriminate patients with HM from immunocompetent patients (areas under the ROC curve, 0.9
238 umannii infections in a cohort of relatively immunocompetent patients (low comorbidity and illness se
239 5), but not in the 27 patient-episodes among immunocompetent patients (P = 1.0), as no neurologic seq
240 Severe Acinetobacter baumannii infections in immunocompetent patients are uncommon, and the virulence
243 s arising after invasive procedures, even in immunocompetent patients in seemingly sterile settings.
244 ation would affect the development of KCs in immunocompetent patients with a history of multiple KCs.
245 data suggest symptomatic treatment alone for immunocompetent patients with HSV meningitis, avoiding t
250 Conclusions and Relevance: In contrast to immunocompetent patients, AGWs of HIV+ MSM may harbor hi
251 ions in both immunocompromised and otherwise immunocompetent patients, although the mechanisms defini
261 reak isolates in particular cause disease in immunocompetent people is unknown, with differing hypoth
264 ned susceptibility of HSV-2 to pritelivir in immunocompetent persons following daily therapy for up t
266 I], 8.7-15) in immunocompromised compared to immunocompetent persons; the case fatality rate was elev
267 hage-like cells in tissue and the release of immunocompetent pre-dendritic cells into the circulation
268 of hCD4/R5/cT1 mice as a highly reproducible immunocompetent preclinical model to evaluate HIV-1 acqu
269 limited capability to establish infection in immunocompetent primates due to its decreased antagonist
270 SO treatment ameliorates colitis severity in immunocompetent rabbits, modulates LPMC immune responses
276 er of purified Tet2-Tet3 DKO iNKT cells into immunocompetent recipient mice resulted in an uncontroll
277 s do not cause significant disease in adult, immunocompetent rodents, these models rely on "rodent-ad
278 ain function of the thymus is to generate an immunocompetent set of T cells not reactive to self.
279 We show that MmuPV1 challenge of the outbred immunocompetent SKH1 strain produces both transient and
283 or the meta-analysis and included 3112 adult immunocompetent study participants with cSCC and 6020 co
285 e spray were compared with nasal washes from immunocompetent subjects during 146 upper respiratory in
286 nd without saline spray during 142 URIs from immunocompetent subjects were 96% and 86% (P = 0.004), r
287 ria of >10 nucleated cells/mul in the CSF of immunocompetent subjects would have reduced HSV-1/2, VZV
289 of cancer-FOXP3 promoted the tumor growth in immunocompetent syngeneic mice but not in immunocompromi
290 ent for negative selection and maturation of immunocompetent T cells with a self-tolerant T cell anti
291 ing in vivo and ex vivo experiments with the immunocompetent TC-1 murine tumor model, we found that m
292 four mouse models, CBA/J and C57BL6/J (both immunocompetent), Tgepsilon26 (an isogenic strain of str
293 c(+) or LysM(+) cells were also sufficiently immunocompetent to raise a protective immune response to
294 breast cancer metastasis that develops in an immunocompetent tumor microenvironment has not been dete
297 virus-associated secondary HLH by infecting immunocompetent wild-type mice with the beta-herpesvirus
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