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   1 e engrafted into neonatal mice that are both immunodeficient and deficient for myelin basic protein. 
     2 ve transfer of diabetes by CD4(+) T cells to immunodeficient and diabetes-resistant NOD.scid mice was
  
  
  
     6 r stromal interaction molecule 1 (STIM1) are immunodeficient and prone to chronic infection by variou
  
     8 tence of TIL after adoptive transfer into an immunodeficient animal model and augments antitumor immu
     9 rounds as a model, we show that ticks fed on immunodeficient animals demonstrate decreased fibrinogen
    10 dation product) were evident in ticks fed on immunodeficient animals in comparison to ticks fed on im
    11 orgement weights were noted for ticks fed on immunodeficient animals in comparison to ticks fed on im
  
  
    14 .v. into antigen-positive, antigen-negative, immunodeficient, antigen-blocked, and antigen-depleted m
    15  syringae strains into virulent pathogens in immunodeficient Arabidopsis thaliana under high humidity
    16  activity in immunocompetent C57BL/6 but not immunodeficient athymic mice, leading to specific immune
    17 ngerhans into the renal subcapsular space of immunodeficient BALB/c.rag2(-/-).cgamma(-/-) mice, previ
  
    19  Humanized nonobese diabetic severe combined immunodeficient common gamma chain-deficient stem cell f
    20 e' whereby monogenic mutations cause primary immunodeficient conditions characterised by impaired imm
    21 ncer cells are orthotopically implanted into immunodeficient consomic strains and tumor metrics are q
  
    23 s is shown to be limited and dependent on an immunodeficient experimental setting that is arguably of
  
  
    26 was attenuated in C57BL/6 wild-type mice and immunodeficient gp91(-/-) phox mice and was effective as
    27 n Toll-like receptor signaling, are severely immunodeficient, highlighting the paramount role of IRAK
    28  hindlimbs of NOD-Rag1(null) IL2rgamma(null) immunodeficient host mice regenerate new vascularized an
    29 ansformed by E1A/Ras and generated tumors in immunodeficient hosts as efficiently as wild-type (WT) t
  
    31 a protocol to engineer humanized bone within immunodeficient hosts, which can be adapted to study the
  
  
    34 elanoma growth in immunocompetent but not in immunodeficient (IFNgamma(-/-), nude, or CD8(-/-)) mice.
    35 tes to these disappointing outcomes using an immunodeficient IL2 receptor gamma (IL2rgamma)-null mous
    36 /-)) Ag-specific Tfh cells were used to help immunodeficient Il21r(-/-) B cells following T-dependent
    37 ontrast to nonobese diabetic severe combined immunodeficient Il2rg(-/-) (NSG) mice, human NK cells in
  
  
    40 munity to C. difficile could be generated in immunodeficient individuals, we infected CD4(-/-) mice a
  
    42 n inhibited ERalpha(+) cell tumorigenesis in immunodeficient mice ( approximately 66% reduction in tu
    43 hen injected into the infarct border zone of immunodeficient mice 1 week after myocardial infarction,
    44  superior expansion capacity in vitro and in immunodeficient mice and induced a superior antitumor ef
    45 compared to lipid after transplantation into immunodeficient mice and led to a higher number of mural
    46 ed purified human HSCs from MDS samples into immunodeficient mice and show that HSCs are the disease-
  
    48 s were transplanted under the KC of diabetic immunodeficient mice at a marginal dose (500 islet equiv
  
    50 ies, and CTLA4(apt)-STAT3 siRNA treatment of immunodeficient mice bearing human T cell lymphomas prom
  
  
    53 mal imaging was performed in severe combined immunodeficient mice bearing solid and disseminated MM t
    54 PV1/MusPV1) induces persistent papillomas in immunodeficient mice but not in common laboratory strain
  
    56 eate primary gastrointestinal (GI) tumors in immunodeficient mice by tail-vein injection rather than 
    57    In addition, attempts were made to infect immunodeficient mice by tick bite or inoculation of tick
  
    59 ability of the cells to long-term repopulate immunodeficient mice compared with equivalent input numb
    60 e imaging of CTS transplanted onto hearts of immunodeficient mice demonstrated survival of </=30% of 
  
  
  
  
    65 Patient-derived xenograft tumours growing in immunodeficient mice exhibited enhanced hypoxia compared
  
  
  
  
  
    71  and significantly prolonged the survival of immunodeficient mice implanted with the transformed HCD-
    72 ochetes occurred in both immunocompetent and immunodeficient mice in a manner indistinguishable from 
    73  T cell activation when used to reconstitute immunodeficient mice in the presence of scurfy fetal liv
    74 arrow aspirates and were s.c. implanted into immunodeficient mice in the presence or absence of cord 
    75 progenitor cells and reduced their growth in immunodeficient mice in vivo, in comparison with NIL alo
  
  
  
    79 (+) hematopoietic stem/progenitor cells into immunodeficient mice leads to robust reconstitution of h
    80  of CD4(+)CD45RB(hi)Nlrp12(-/-) T cells into immunodeficient mice led to more severe colitis and atop
    81 landular transplantation of cultured MSCs in immunodeficient mice led to their engraftment in the inj
    82 eekly injections of 1 mg kg(-1) of mRNA into immunodeficient mice maintain trough VRC01 levels above 
    83 orted that reconstitution of CD3+ T cells in immunodeficient mice mimics ART-induced bone loss observ
    84  have focused on the historic development of immunodeficient mice over the last 2 decades, as well as
    85 ers as fetal human thymus (HU THY) grafts in immunodeficient mice receiving the same human CD34(+) ce
    86  had approximately equal abilities to infect immunodeficient mice reconstituted with a human hematopo
  
    88  in human cancer cell lines xenografted into immunodeficient mice resulted in activation of canonical
    89 PM-ALK-transformed CD4(+) T lymphocytes into immunodeficient mice resulted in formation of tumors ind
    90 ent of human GPCs in normally myelinated and immunodeficient mice resulted in humanized white matter 
    91 antation of transduced FA CD34(+) cells into immunodeficient mice resulted in reproducible engraftmen
    92 le fiber fragments into irradiated muscle of immunodeficient mice resulted in robust engraftment, mus
    93  Transplantation of CYTH1-knockdown cells to immunodeficient mice resulted in significantly lower lon
    94 c implant of CCA human cells in the liver of immunodeficient mice resulted in the release to serum of
    95 e seminiferous tubules of germ cell-depleted immunodeficient mice revealed divergent fates of iPSCs p
  
    97 alp hair follicles onto chemotherapy-treated immunodeficient mice serves as an excellent in vivo mode
    98 n of day 20 CMs into the infarcted hearts of immunodeficient mice showed good engraftment, and echoca
  
  
  
   102 gical tolerance unfold in mutant mice and in immunodeficient mice that received p53cKO-derived thymoc
   103 was induced in human arteries engrafted into immunodeficient mice that were reconstituted with T cell
   104 l of s.c. human tumor xenografts in severely immunodeficient mice to assess the antitumor efficacy of
   105 esponse of human hair follicles grafted onto immunodeficient mice to cyclophosphamide resembles the k
   106 t diseases, followed by transplantation into immunodeficient mice to generate genetic models of clona
  
  
   109 y positron emission tomography as well as in immunodeficient mice transplanted with human islets unde
   110 nt donor cells were significantly reduced in immunodeficient mice transplanted with MF CD34(+) cell g
  
  
   113 r radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-
   114 g effect of hypoxia on tumor initiation into immunodeficient mice using human non-small lung carcinom
  
   116 M21 (human melanoma)-bearing severe combined immunodeficient mice were used for biodistribution, PET 
   117 ions of humanized mice generated in severely immunodeficient mice with a targeted disruption of the I
   118 monstrated in human CD46 transgenic mice and immunodeficient mice with engrafted human CD34(+) cells 
   119 n the spinal cord and dorsal root ganglia of immunodeficient mice with higher efficacy than AAV2, 5, 
   120   Attempts to superinfect different types of immunodeficient mice with homologous B. burgdorferi indi
   121  third model was generated by reconstituting immunodeficient mice with human CD34+ hematopoietic stem
  
   123  slow tumor progression when administered to immunodeficient mice with intracranial human glioma xeno
   124 kinase plasminogen activator-severe combined immunodeficient mice with livers repopulated with human 
   125 n HD glial chimeras by neonatally engrafting immunodeficient mice with mutant huntingtin (mHTT)-expre
  
   127 metastasis, and mortality of severe combined immunodeficient mice xenografted with PC3 or DU145 cells
   128  HSCs with >6-month repopulating activity in immunodeficient mice) displayed rapid increases in activ
   129 ter xenotransplantation into severe-combined-immunodeficient mice, (3) expression of platelet-derived
   130 d human TECs, human thymic tissue grafted to immunodeficient mice, and murine fetal thymus organ cult
   131 sduced BM CD34+ cells were transplanted into immunodeficient mice, and the human cells recovered afte
   132 ient-derived RCC samples into the kidneys of immunodeficient mice, as well as the s.c. implantation f
   133 rs and transplanted them into hyperglycemic, immunodeficient mice, beta cell replication increased mo
   134  as well as their efficiency in repopulating immunodeficient mice, both in the presence and absence o
  
   136 antitumor activity in immunocompetent versus immunodeficient mice, demonstrating a contribution of th
  
  
   139  myeloid cells in vitro and can also engraft immunodeficient mice, generating myeloerythoid and B-lym
  
   141  studying human malignant and normal HSCs in immunodeficient mice, including newly developed mice for
   142 euroblastoma tumor engraftment and growth in immunodeficient mice, indicating an effect independent o
  
   144 tation of miR-377 silenced hCD34(+) cells in immunodeficient mice, promoting neovascularization (at 2
  
   146 upon xenograft transplantation of cells into immunodeficient mice, the dominant-negative GRK2-K220R o
   147 ransduced with the oncogene combination into immunodeficient mice, we generate a fatal B malignancy w
   148 n of vascularized condensed progenitors into immunodeficient mice, we used an intravital imaging appr
   149 ong-term reconstitution when transplanted in immunodeficient mice, were present in the chorion from 1
   150 andates awareness of replicating MuLV in NOD immunodeficient mice, which can significantly influence 
   151 erformed in tumour xenografts in 15 NCr nude immunodeficient mice, which were treated with either the
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
   217 o HSC cells in their ability to reconstitute immunodeficient mice; however, dnMaml-transduced HSCs we
   218 d/or injected into flanks of severe combined immunodeficient mice; xenograft tumor growth and metasta
  
  
   221 emination defect in immunocompetent, but not immunodeficient, mice, and the defect was found to resol
  
  
   224  cells and promotes osteolysis in vivo in an immunodeficient mouse model of bone metastasis through u
   225 of a DMD patient (mdcs) transplanted into an immunodeficient mouse model of DMD, we report that two n
  
  
  
  
  
  
  
   233 rial transfer was observed in vivo in an NSG immunodeficient mouse xenograft model and also occurred 
   234 ve activities in TSC2-deficient cells and an immunodeficient mouse xenograft model of lymphangioleiom
  
  
  
   238 ge in competition experiments carried out in immunodeficient MyD88-knockout mice or in neutrophil-dep
   239 lting in the diagnosis of a higher number of immunodeficient newborns than previously estimated.     
   240 nes, and human B cell activation factor into immunodeficient NOD scid gamma (NSG) mice by the use of 
  
  
   243 D19(+) B cell population after transfer into immunodeficient NOD.Cg-Prkdc(scid) Il2rg(tm1wjl)/SxJ neo
  
   245 ic application of the Fcmu-drug conjugate in immunodeficient NOD/SCID/IL-2Rgamma(null) (NSG) mice eng
   246 abeled cell sorting and transplantation into immunodeficient NOD/SCID/interleukin 2 receptor gamma ch
   247 cidence in nonobese diabetic/severe combined immunodeficient (NOD/SCID) Ilgamma2(null) mice and deepe
   248 h CML by using xenotransplant experiments in immunodeficient NOG mice, and we showed that engraftment
  
  
   251 S/G2-phase human HSCs after engraftment into immunodeficient (NSG) mice, a phenotype that is associat
   252 s (HSPCs) expressing MLL-AF9 or MLL-Af4 into immunodeficient NSGS mice, which strongly promote myeloi
  
  
   255 hese recommendations address the concern for immunodeficient patients acquiring infections from healt
   256  is usually safe but cannot be given to many immunodeficient patients and retains the capacity to est
   257  viral or bacterial vaccines can be given to immunodeficient patients and the growing neglect of soci
  
   259  or vaccine-derived diseases being spread to immunodeficient patients at risk for close-contact sprea
   260 effort to evaluate serum from autoimmune and immunodeficient patients for Abs against cytokines, chem
   261 rvations support the concept that some DOCK8-immunodeficient patients have mutable mosaic genomes tha
   262  to incriminate single-gene inborn errors in immunodeficient patients results from the relative ease 
  
   264 nalizes more than 60 mutations identified in immunodeficient patients, as well as a large body of gen
   265 ines are essential for disease prevention in immunodeficient patients, just as they are for healthy s
  
  
  
   269 excretion of vaccine-derived polioviruses by immunodeficient persons (iVDPV) presents a personal risk
   270 iated NOD2 mutations could cause a primarily immunodeficient phenotype by selectively impairing TLR4-
   271 ict B cell signaling could contribute to the immunodeficient phenotype of these mice and is consisten
  
  
  
   275  of SGM (e.g. FOXN1, RAG2, IL2RG, and PRKDC) immunodeficient rabbits, as well as multigenic mutant im
   276  By serially transplanting hyperplasias into immunodeficient rag1 mutant zebrafish, we succeeded in l
  
  
   279 doptive transfer of TRAIL-null NK cells into immunodeficient RAG2/common gamma-null mice was associat
   280 vertheless, when adoptively transferred into immunodeficient Rai(+/+) mice, these cells promoted a mo
  
  
   283 nctive B cell progeny when transplanted into immunodeficient recipients, supporting a two-pathway mod
  
  
   286 of MEDI-575 in tumor-bearing severe combined immunodeficient (SCID) mice and in genetically altered S
   287  after 24 serial passages in severe combined immunodeficient (SCID) mice caused severe disease when a
  
  
   290 bjected to DNFB-induced CHS, severe combined immunodeficient (SCID) mice were injected with CD4(+) T 
  
  
  
   294 lium-free mammary fat pad of severe combined immunodeficient (SCID)/Beige and nonobese diabetic (NOD)
  
  
   297 nd cellular vaccine responses in healthy and immunodeficient subjects and how that knowledge can then
  
  
  
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