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1 e engrafted into neonatal mice that are both immunodeficient and deficient for myelin basic protein.
2 ve transfer of diabetes by CD4(+) T cells to immunodeficient and diabetes-resistant NOD.scid mice was
6 r stromal interaction molecule 1 (STIM1) are immunodeficient and prone to chronic infection by variou
8 tence of TIL after adoptive transfer into an immunodeficient animal model and augments antitumor immu
9 rounds as a model, we show that ticks fed on immunodeficient animals demonstrate decreased fibrinogen
10 dation product) were evident in ticks fed on immunodeficient animals in comparison to ticks fed on im
11 orgement weights were noted for ticks fed on immunodeficient animals in comparison to ticks fed on im
14 .v. into antigen-positive, antigen-negative, immunodeficient, antigen-blocked, and antigen-depleted m
15 syringae strains into virulent pathogens in immunodeficient Arabidopsis thaliana under high humidity
16 activity in immunocompetent C57BL/6 but not immunodeficient athymic mice, leading to specific immune
17 ngerhans into the renal subcapsular space of immunodeficient BALB/c.rag2(-/-).cgamma(-/-) mice, previ
19 Humanized nonobese diabetic severe combined immunodeficient common gamma chain-deficient stem cell f
20 e' whereby monogenic mutations cause primary immunodeficient conditions characterised by impaired imm
21 ncer cells are orthotopically implanted into immunodeficient consomic strains and tumor metrics are q
23 s is shown to be limited and dependent on an immunodeficient experimental setting that is arguably of
26 was attenuated in C57BL/6 wild-type mice and immunodeficient gp91(-/-) phox mice and was effective as
27 n Toll-like receptor signaling, are severely immunodeficient, highlighting the paramount role of IRAK
28 hindlimbs of NOD-Rag1(null) IL2rgamma(null) immunodeficient host mice regenerate new vascularized an
29 ansformed by E1A/Ras and generated tumors in immunodeficient hosts as efficiently as wild-type (WT) t
31 a protocol to engineer humanized bone within immunodeficient hosts, which can be adapted to study the
34 elanoma growth in immunocompetent but not in immunodeficient (IFNgamma(-/-), nude, or CD8(-/-)) mice.
35 tes to these disappointing outcomes using an immunodeficient IL2 receptor gamma (IL2rgamma)-null mous
36 /-)) Ag-specific Tfh cells were used to help immunodeficient Il21r(-/-) B cells following T-dependent
37 ontrast to nonobese diabetic severe combined immunodeficient Il2rg(-/-) (NSG) mice, human NK cells in
40 munity to C. difficile could be generated in immunodeficient individuals, we infected CD4(-/-) mice a
42 n inhibited ERalpha(+) cell tumorigenesis in immunodeficient mice ( approximately 66% reduction in tu
43 hen injected into the infarct border zone of immunodeficient mice 1 week after myocardial infarction,
44 superior expansion capacity in vitro and in immunodeficient mice and induced a superior antitumor ef
45 compared to lipid after transplantation into immunodeficient mice and led to a higher number of mural
46 ed purified human HSCs from MDS samples into immunodeficient mice and show that HSCs are the disease-
48 s were transplanted under the KC of diabetic immunodeficient mice at a marginal dose (500 islet equiv
50 ies, and CTLA4(apt)-STAT3 siRNA treatment of immunodeficient mice bearing human T cell lymphomas prom
53 mal imaging was performed in severe combined immunodeficient mice bearing solid and disseminated MM t
54 PV1/MusPV1) induces persistent papillomas in immunodeficient mice but not in common laboratory strain
56 eate primary gastrointestinal (GI) tumors in immunodeficient mice by tail-vein injection rather than
57 In addition, attempts were made to infect immunodeficient mice by tick bite or inoculation of tick
59 ability of the cells to long-term repopulate immunodeficient mice compared with equivalent input numb
60 e imaging of CTS transplanted onto hearts of immunodeficient mice demonstrated survival of </=30% of
65 Patient-derived xenograft tumours growing in immunodeficient mice exhibited enhanced hypoxia compared
71 and significantly prolonged the survival of immunodeficient mice implanted with the transformed HCD-
72 ochetes occurred in both immunocompetent and immunodeficient mice in a manner indistinguishable from
73 T cell activation when used to reconstitute immunodeficient mice in the presence of scurfy fetal liv
74 arrow aspirates and were s.c. implanted into immunodeficient mice in the presence or absence of cord
75 progenitor cells and reduced their growth in immunodeficient mice in vivo, in comparison with NIL alo
79 (+) hematopoietic stem/progenitor cells into immunodeficient mice leads to robust reconstitution of h
80 of CD4(+)CD45RB(hi)Nlrp12(-/-) T cells into immunodeficient mice led to more severe colitis and atop
81 landular transplantation of cultured MSCs in immunodeficient mice led to their engraftment in the inj
82 eekly injections of 1 mg kg(-1) of mRNA into immunodeficient mice maintain trough VRC01 levels above
83 orted that reconstitution of CD3+ T cells in immunodeficient mice mimics ART-induced bone loss observ
84 have focused on the historic development of immunodeficient mice over the last 2 decades, as well as
85 ers as fetal human thymus (HU THY) grafts in immunodeficient mice receiving the same human CD34(+) ce
86 had approximately equal abilities to infect immunodeficient mice reconstituted with a human hematopo
88 in human cancer cell lines xenografted into immunodeficient mice resulted in activation of canonical
89 PM-ALK-transformed CD4(+) T lymphocytes into immunodeficient mice resulted in formation of tumors ind
90 ent of human GPCs in normally myelinated and immunodeficient mice resulted in humanized white matter
91 antation of transduced FA CD34(+) cells into immunodeficient mice resulted in reproducible engraftmen
92 le fiber fragments into irradiated muscle of immunodeficient mice resulted in robust engraftment, mus
93 Transplantation of CYTH1-knockdown cells to immunodeficient mice resulted in significantly lower lon
94 c implant of CCA human cells in the liver of immunodeficient mice resulted in the release to serum of
95 e seminiferous tubules of germ cell-depleted immunodeficient mice revealed divergent fates of iPSCs p
97 alp hair follicles onto chemotherapy-treated immunodeficient mice serves as an excellent in vivo mode
98 n of day 20 CMs into the infarcted hearts of immunodeficient mice showed good engraftment, and echoca
102 gical tolerance unfold in mutant mice and in immunodeficient mice that received p53cKO-derived thymoc
103 was induced in human arteries engrafted into immunodeficient mice that were reconstituted with T cell
104 l of s.c. human tumor xenografts in severely immunodeficient mice to assess the antitumor efficacy of
105 esponse of human hair follicles grafted onto immunodeficient mice to cyclophosphamide resembles the k
106 t diseases, followed by transplantation into immunodeficient mice to generate genetic models of clona
109 y positron emission tomography as well as in immunodeficient mice transplanted with human islets unde
110 nt donor cells were significantly reduced in immunodeficient mice transplanted with MF CD34(+) cell g
113 r radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-
114 g effect of hypoxia on tumor initiation into immunodeficient mice using human non-small lung carcinom
116 M21 (human melanoma)-bearing severe combined immunodeficient mice were used for biodistribution, PET
117 ions of humanized mice generated in severely immunodeficient mice with a targeted disruption of the I
118 monstrated in human CD46 transgenic mice and immunodeficient mice with engrafted human CD34(+) cells
119 n the spinal cord and dorsal root ganglia of immunodeficient mice with higher efficacy than AAV2, 5,
120 Attempts to superinfect different types of immunodeficient mice with homologous B. burgdorferi indi
121 third model was generated by reconstituting immunodeficient mice with human CD34+ hematopoietic stem
123 slow tumor progression when administered to immunodeficient mice with intracranial human glioma xeno
124 kinase plasminogen activator-severe combined immunodeficient mice with livers repopulated with human
125 n HD glial chimeras by neonatally engrafting immunodeficient mice with mutant huntingtin (mHTT)-expre
127 metastasis, and mortality of severe combined immunodeficient mice xenografted with PC3 or DU145 cells
128 HSCs with >6-month repopulating activity in immunodeficient mice) displayed rapid increases in activ
129 ter xenotransplantation into severe-combined-immunodeficient mice, (3) expression of platelet-derived
130 d human TECs, human thymic tissue grafted to immunodeficient mice, and murine fetal thymus organ cult
131 sduced BM CD34+ cells were transplanted into immunodeficient mice, and the human cells recovered afte
132 ient-derived RCC samples into the kidneys of immunodeficient mice, as well as the s.c. implantation f
133 rs and transplanted them into hyperglycemic, immunodeficient mice, beta cell replication increased mo
134 as well as their efficiency in repopulating immunodeficient mice, both in the presence and absence o
136 antitumor activity in immunocompetent versus immunodeficient mice, demonstrating a contribution of th
139 myeloid cells in vitro and can also engraft immunodeficient mice, generating myeloerythoid and B-lym
141 studying human malignant and normal HSCs in immunodeficient mice, including newly developed mice for
142 euroblastoma tumor engraftment and growth in immunodeficient mice, indicating an effect independent o
144 tation of miR-377 silenced hCD34(+) cells in immunodeficient mice, promoting neovascularization (at 2
146 upon xenograft transplantation of cells into immunodeficient mice, the dominant-negative GRK2-K220R o
147 ransduced with the oncogene combination into immunodeficient mice, we generate a fatal B malignancy w
148 n of vascularized condensed progenitors into immunodeficient mice, we used an intravital imaging appr
149 ong-term reconstitution when transplanted in immunodeficient mice, were present in the chorion from 1
150 andates awareness of replicating MuLV in NOD immunodeficient mice, which can significantly influence
151 erformed in tumour xenografts in 15 NCr nude immunodeficient mice, which were treated with either the
217 o HSC cells in their ability to reconstitute immunodeficient mice; however, dnMaml-transduced HSCs we
218 d/or injected into flanks of severe combined immunodeficient mice; xenograft tumor growth and metasta
221 emination defect in immunocompetent, but not immunodeficient, mice, and the defect was found to resol
224 cells and promotes osteolysis in vivo in an immunodeficient mouse model of bone metastasis through u
225 of a DMD patient (mdcs) transplanted into an immunodeficient mouse model of DMD, we report that two n
233 rial transfer was observed in vivo in an NSG immunodeficient mouse xenograft model and also occurred
234 ve activities in TSC2-deficient cells and an immunodeficient mouse xenograft model of lymphangioleiom
238 ge in competition experiments carried out in immunodeficient MyD88-knockout mice or in neutrophil-dep
239 lting in the diagnosis of a higher number of immunodeficient newborns than previously estimated.
240 nes, and human B cell activation factor into immunodeficient NOD scid gamma (NSG) mice by the use of
243 D19(+) B cell population after transfer into immunodeficient NOD.Cg-Prkdc(scid) Il2rg(tm1wjl)/SxJ neo
245 ic application of the Fcmu-drug conjugate in immunodeficient NOD/SCID/IL-2Rgamma(null) (NSG) mice eng
246 abeled cell sorting and transplantation into immunodeficient NOD/SCID/interleukin 2 receptor gamma ch
247 cidence in nonobese diabetic/severe combined immunodeficient (NOD/SCID) Ilgamma2(null) mice and deepe
248 h CML by using xenotransplant experiments in immunodeficient NOG mice, and we showed that engraftment
251 S/G2-phase human HSCs after engraftment into immunodeficient (NSG) mice, a phenotype that is associat
252 s (HSPCs) expressing MLL-AF9 or MLL-Af4 into immunodeficient NSGS mice, which strongly promote myeloi
255 hese recommendations address the concern for immunodeficient patients acquiring infections from healt
256 is usually safe but cannot be given to many immunodeficient patients and retains the capacity to est
257 viral or bacterial vaccines can be given to immunodeficient patients and the growing neglect of soci
259 or vaccine-derived diseases being spread to immunodeficient patients at risk for close-contact sprea
260 effort to evaluate serum from autoimmune and immunodeficient patients for Abs against cytokines, chem
261 rvations support the concept that some DOCK8-immunodeficient patients have mutable mosaic genomes tha
262 to incriminate single-gene inborn errors in immunodeficient patients results from the relative ease
264 nalizes more than 60 mutations identified in immunodeficient patients, as well as a large body of gen
265 ines are essential for disease prevention in immunodeficient patients, just as they are for healthy s
269 excretion of vaccine-derived polioviruses by immunodeficient persons (iVDPV) presents a personal risk
270 iated NOD2 mutations could cause a primarily immunodeficient phenotype by selectively impairing TLR4-
271 ict B cell signaling could contribute to the immunodeficient phenotype of these mice and is consisten
275 of SGM (e.g. FOXN1, RAG2, IL2RG, and PRKDC) immunodeficient rabbits, as well as multigenic mutant im
276 By serially transplanting hyperplasias into immunodeficient rag1 mutant zebrafish, we succeeded in l
279 doptive transfer of TRAIL-null NK cells into immunodeficient RAG2/common gamma-null mice was associat
280 vertheless, when adoptively transferred into immunodeficient Rai(+/+) mice, these cells promoted a mo
283 nctive B cell progeny when transplanted into immunodeficient recipients, supporting a two-pathway mod
286 of MEDI-575 in tumor-bearing severe combined immunodeficient (SCID) mice and in genetically altered S
287 after 24 serial passages in severe combined immunodeficient (SCID) mice caused severe disease when a
290 bjected to DNFB-induced CHS, severe combined immunodeficient (SCID) mice were injected with CD4(+) T
294 lium-free mammary fat pad of severe combined immunodeficient (SCID)/Beige and nonobese diabetic (NOD)
297 nd cellular vaccine responses in healthy and immunodeficient subjects and how that knowledge can then
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