ライフサイエンスコーパス: immunodominant

1 535 and 673, indicating that this region is immunodominant.

2 both O-antigen modifications were generally immunodominant.

3 omponents appear to fortuitously process the immunodominant Ag85B, facilitating immune recognition.

4 cally using IFN-gamma and IL-2 ELISPOT using immunodominant Ags (Acr-1, CFP-10, ESAT-6) as references

5 om infected humans to probe for responses to immunodominant Ags in the M. tuberculosis cell wall.

6 Allergenic extracts that have multiple immunodominant allergenic proteins are standardized with

7 ogenic T cell response is directed toward an immunodominant alpha-gliadin-derived peptide (DQ8-glia-a

8 Glucose monomycolate was immunodominant among lipid Ags tested, and polyfunctiona

9 press early secretory antigen 6 (ESAT-6), an immunodominant and diagnostic antigen from Mycobacterium

10 ed two core regions overlapping the two most immunodominant and frequently studied CD4 T cell targets

11 The latter are immunodominant and induce nonneutralizing antibodies.

12 Some epitopes were highly immunodominant and specific to either T1D children (GAD(

13 Its outer membrane protein B (OmpB) is an immunodominant antigen and plays roles as protective env

14 the secreted C. trachomatis protein Pgp3, an immunodominant antigen and putative virulence factor.

15 lymphocyte responses against an independent immunodominant antigen in mice, indicating orchestration

16 n side chain of the lipopolysaccharide is an immunodominant antigen, can define host-pathogen interac

17 lymorphic antigen-presenting molecule and an immunodominant antigen.

18 t cell adhesion and invasion, and is a major immunodominant antigen.

19 G extract or a pool of previously identified immunodominant antigenic regions.

20 of human monoclonal antibodies can identify immunodominant antigenic sites associated with neutraliz

21 Antibody diversity analysis revealed immunodominant antigenic sites in the N- and C-termini o

22 the hemagglutinin head domain to shield the immunodominant antigenic sites.

23 itive individuals; (iii) panels of 21 and 30 immunodominant antigens (ID-Ags) were identified from th

24 enhanced T cell immunity to nine of fifteen immunodominant antigens analysed including AhpC (BPSL209

25 mice and humans, demonstrating flagellins as immunodominant antigens in the intestines.

26 The immunodominant antigens that elicit the protective antib

27 C. muridarum proteins as antigens and 17 as immunodominant antigens.

28 ore antisera, the latter being designated as immunodominant antigens.

29 ble prolamins that was achieved choosing the immunodominant apolar peptide from alpha2-gliadin as a t

30 intensities comparable to those observed for immunodominant areas of the surface component gp120.

31 arasite invasion in vitro Neither protein is immunodominant, as both proteins react only marginally w

32 HSV-1 and HSV-2 immunodominant "asymptomatic" antigens (ID-A-Ags), which

33 T cell epitopes were genetically fused to an immunodominant B cell epitope derived from the N-termina

34 The identified immunodominant B cell epitopes provide a better understa

35 Ten immunodominant B cell epitopes were identified: CbpD-pep

36 The identification of immunodominant B cell epitopes within surface pneumococc

37 mma-gliadins, and their deamidated forms, as immunodominant B-cell epitopes in wheat and related cere

38 table pathologic antibody repertoires to the immunodominant B-cell epitopes of the major peanut aller

39 , which demonstrated that the VP2 epitope is immunodominant between EV71 and CA16.

40 ctively dampen immune responses to undesired immunodominant bridging sheet determinants.

41 ng a therapeutic antibody, we employed a non-immunodominant, but functionally relevant, epitope in do

42 s in the human TCR repertoire targeted at an immunodominant, but highly mutable, HLA-B*0801-restricte

43 nd for multiple HLA targets, considering the immunodominant, but not the sum, of antibodies MFI.

44 The current study, by mapping immunodominant C. trachomatis antigens and identifying a

45 The immunodominant CD4 T-cell antigens included both long pr

46 utoimmune renal disorder characterized by an immunodominant CD4(+) T-cell self-epitope derived from t

47 Vax) of an M2(82-90) peptide representing an immunodominant CD8 epitope, the Toll-like receptor (TLR)

48 ced neutralizing Abs but contains conserved, immunodominant CD8 T cell epitopes.

49 We characterized two immunodominant CD8 T cell populations generated in respo

50 LCMV infection (7 of 36) developed a robust immunodominant CD8 T cell response apparently cross-reac

51 of the C57BL/6 strain of mice, in which the immunodominant CD8 T cell response to the parasite dense

52 full length of 21-hydroxylase, we identified immunodominant CD8(+) and CD4(+) T cell responses in a l

53 rminal domain contains an epitope that is an immunodominant CD8(+) T cell antigen during primary infe

54 tein glycoprotein B (gB) contains a strongly immunodominant CD8(+) T cell epitope (gB(498-505)) that

55 Polymorphism of immunodominant CD8(+) T cell epitopes can facilitate esc

56 dence of variation in epitopes recognized by immunodominant CD8(+) T lymphocytes, implying that these

57 RM9, and Rev(5)(9)(-)(6)(8)SP10) targeted by immunodominant CD8+ T cell responses in acutely infected

58 ution of slpA and nearby genes also encoding immunodominant cell surface antigens.

59 Tetramer staining for the immunodominant circumsporozoite protein (CSP)-specific C

60 The median MFI of the immunodominant class I or II DSA in the peak or day 0 se

61 o identify lipoproteins as an unexpected and immunodominant class of cell wall-associated Ags targete

62 ecause subdominant TCD8 are more likely than immunodominant clones to escape tolerance mechanisms and

63 g T cell receptors (TCRs) that recognize the immunodominant CMV epitope NLVPMVATV (NLV).

64 mune response predominantly directed against immunodominant conserved T cell epitopes.

65 major CTL target Ag and pp65(495-503) is an immunodominant CTL epitope in infected HLA-A*0201 indivi

66 presentation for target cell recognition by immunodominant CTL was tested by small interfering RNA t

67 We have discovered an immunodominant cytolytic T lymphocyte (CTL) epitope enco

68 d Triplex by constructing an rMVA encoding 3 immunodominant cytomegalovirus (CMV) antigens, which sti

69 ited a strong CD8 T-cell response toward the immunodominant D(b)-restricted TMEV-derived peptide, VP2

70 us-specific CD8(+) T cells responding to the immunodominant D(b)NP366 epitope.

71 vigorously to p61-80, a naturally processed immunodominant determinant of intact AQP4.

72 op region of gp41 is also known as principal immunodominant domain (PID) because of its high immunoge

73 disulfide loop region (DLR) of the principal immunodominant domain of gp41, recognized by the well-kn

74 We have demonstrated that immunodominant donor-specific antibody (DSA) more than 1

75 Immunodominant donor-specific antibody (iDSA) was define

76 pecific CD4(+) T cell responses targeting an immunodominant DRB1*11-Gag41 complex and HIV control, hi

77 The MFI of the immunodominant DSA (iDSA, the DSA with the highest MFI l

78 Although mean fluorescence intensity of the immunodominant DSA diagnosed ABMR (AUC=0.75; 95% CI, 0.6

79 ; P<0.001), combining urinary CXCL10:Cr with immunodominant DSA levels improved the diagnosis of ABMR

80 divided into three protocols based on their immunodominant DSA MFI pretransplant (D1: 100-500, D2: 5

81 antibodies are better evaluated through the immunodominant DSA MFI than through the sum of DSA MFI.

82 We show that CD4(+) T cells recognizing immunodominant Dsg3 epitopes in the context of the PV-as

83 9, and 638 to 651, instead of the well-known immunodominant E2 hypervariable region 1 (HVR1).

84 hat memory CD8 T cells specific for a single immunodominant epitope (S436 or S525) substantially prot

85 ur-TCR-Tg]) expressing a TCR recognizing the immunodominant epitope (Sur20-28) of murine survivin dur

86 dent increase in the surface exposure of the immunodominant epitope (V86-T98) as determined by antibo

87 essive effector memory CTLs specific for the immunodominant epitope 40-48 of myelin oligodendrocyte g

88 This immunodominant epitope bound stably to DQ2.2.

89 Located within a single CP subunit is an immunodominant epitope consisting of residues 169 to 180

90 DC increased cross-presentation of E75, the immunodominant epitope derived from the HER2 protein, an

91 unctionality, whereas those specific for the immunodominant epitope exhibit increased functionality i

92 We found a single, highly immunodominant epitope in 46% (23/50) of the donors.

93 These results indicate that the immunodominant epitope in PLA2R is exclusively located i

94 core shells with an antibody specific to the immunodominant epitope is compared to the constructs wit

95 The immunodominant epitope is DRB1-restricted and was observ

96 The mapped 12-amino acid immunodominant epitope lies within a "hinge" region betw

97 s optica (NMO) patients, which recognize the immunodominant epitope of aquaporin-4, exhibit Th17 pola

98 y using a human T-cell line specific for the immunodominant epitope of Bet v 1 and in vivo in an adju

99 Specifically, an immunodominant epitope of EV71 that maps to the virus ca

100 t viral replication through targeting of the immunodominant epitope of group-associated antigen (Gag)

101 t recombinant L. monocytogenes expressing an immunodominant epitope of the LCMV glycoprotein (GP33) w

102 ice, half of these cells are specific for an immunodominant epitope on HSV-1 glycoprotein B, whereas

103 maintain a 1:1 ratio of cells recognizing an immunodominant epitope on viral glycoprotein B (gB498-50

104 In addition, 26D1 epitope is immunodominant epitope recognized by both antibodies eli

105 The mutated PPP1R3B peptide represents the immunodominant epitope recognized by tumor-reactive T ce

106 Here, we identified the immunodominant epitope region in PLA2R by probing isolat

107 elated with overall sequence homology, and 2 immunodominant epitope regions of Phl p 12 were identifi

108 or residue, thereby abrogating activation of immunodominant epitope responses.

109 e was shifted from the previously identified immunodominant epitope to a novel epitope when the antig

110 clonal, polymeric IgA antibody that binds an immunodominant epitope within the O-antigen (O-Ag) compo

111 eleted or mutated to alanine, eliminated the immunodominant epitope, and we used this information to

112 he fate of this peptide from a cryptic to an immunodominant epitope.

113 a vaccine expressing the same Ag without its immunodominant epitope.

114 We show that ANT1 encompasses multiple immunodominant epitopes (namely, ANT1 21-40, ANT1 31-50,

115 Five immunodominant epitopes accounted for more than half of

116 Progress in defining the immunodominant epitopes and how neutralizing antibodies

117 Immunodominant epitopes are few selected epitopes from c

118 Autoantigen-derived immunodominant epitopes are resistant to digestion by ca

119 nduced CD8(+) T-cell responses against three immunodominant epitopes can increase the incidence of el

120 and transient exposure of non-neutralizing, immunodominant epitopes could hinder the induction of br

121 vant-free mix of three peptides that include immunodominant epitopes for gluten-specific CD4-positive

122 Unlike most pathogens, many of the immunodominant epitopes from Mycobacterium tuberculosis

123 s on and responds to very few representative immunodominant epitopes from pathogenic insults.

124 II-restricted processing and presentation of immunodominant epitopes from the major house dust mite a

125 D8(+) T cell responses of cattle against two immunodominant epitopes from Theileria parva (Tp1(214-22

126 Immunodominant epitopes highly conserved across genotype

127 ts to the importance of internal residues as immunodominant epitopes in (1-->2)-beta-mannans and to t

128 These findings implicate immunodominant epitopes in the pathology of ANCA-associa

129 ain these epitopes but lack the variable and immunodominant epitopes located in the globular head of

130 g without limiting virus viability, and also immunodominant epitopes located in variable regions.

131 CD8(+) T cell immunodominant epitopes of alpha-NAC were mapped by appl

132 cted autoreactive CD4(+) T cells recognizing immunodominant epitopes of Dsg3 initiate the production

133 ead consistent with periodic turnover of the immunodominant epitopes of PfEMP1 associated with severe

134 entameric B subunit of CT (CTB) contains the immunodominant epitopes recognized by antibodies that ne

135 virus (HIV) escape mutations often arise in immunodominant epitopes recognized by MHC class I allele

136 N specifically inhibited the response to two immunodominant epitopes that are known to be dependent o

137 jor histocompatibility complex (MHC) class I immunodominant epitopes using an overlapping peptide scr

138 T-cell IFN-gamma immunity to OprF and its immunodominant epitopes was characterized.

139 human leukocyte antigen (HLA) restriction of immunodominant epitopes were defined using HLA class II

140 One to 3 major cN1A immunodominant epitopes were identified.

141 Immunodominant epitopes were the most efficacious in lon

142 Epitope mapping of LipC identified 6 immunodominant epitopes, 5 of which map to the exposed s

143 K288S/Y176F, a variant mutated in one of the immunodominant epitopes, showed reduced antigenicity.

144 class II molecules and included most of the immunodominant epitopes.

145 ssed HLA class II molecules and knowledge of immunodominant epitopes.

146 he size of the CD8(+) T cell response to two immunodominant epitopes.

147 rnary epitopes and V1/V2-mediated masking of immunodominant epitopes.

148 can distort the capture of the physiological immunodominant epitopes.

149 ic mice that are centrally tolerant to these immunodominant epitopes.

150 y landscape in favor of MHC I complexes with immunodominant epitopes.

151 ese results identify the A5.1 mutation as an immunodominant factor and a potential risk factor for tr

152 xposed MPER tryptophan residue (Trp-680) was immunodominant, focusing immune responses, despite seque

153 dominant, conserved lateral patch had become immunodominant for individuals with B-cell memory imprin

154 m of regulation, as well as whether a single immunodominant form of synthetic sulfatide can treat ong

155 abbit IgG against the murine homologs of two immunodominant fragments in adult C57BL/6 mice (mLAMalph

156 Antibodies to linear epitopes, including the immunodominant fusion-loop epitope, were able to bind ZI

157 neous application of FVIII involved the same immunodominant FVIII epitopes.

158 ere, we defined the MHC class II alleles for immunodominant Gag CD4(+) T cell epitopes in clade C vir

159 ween HIV-specific CD4(+) T cell targeting of immunodominant Gag epitopes and immune control, particul

160 employed MHC class II tetramers designed to immunodominant Gag epitopes and used them to characteriz

161 ctedly higher functional avidity than is the immunodominant Gag-recognizing counterpart.

162 Importantly, targeting of the immunodominant Gag41 peptide in the context of HLA class

163 ut strain specific due to their focus on the immunodominant globular head domain of the hemagglutinin

164 ndividuals do not mount a T cell response to immunodominant gluten epitopes of CD.

165 have used tetramers of HLA-DQ2.5 bound with immunodominant gluten epitopes to explore whether HLA-DQ

166 receptor (TCR) repertoires directed to some immunodominant gluten peptides have previously been desc

167 During NCC, the parasites release immunodominant glycan antigens in the CNS environment, i

168 ocompatibility complex multimers against the immunodominant H4, H7, H13, H28, and H60 minor Ags.

169 agglutinin consists of a highly variable and immunodominant head domain and a more conserved but immu

170 ilized-stem (HA-SS) immunogens that lack the immunodominant head domain.

171 cells are directed predominantly toward the immunodominant Her-2/neu (neu) epitope RNEU(420-429) in

172 ell-mediated adaptive immunity by presenting immunodominant HIV epitopes to cytotoxic T lymphocytes (

173 cts against HIV disease progression, but the immunodominant HLA-B*14-restricted anti-HIV response is

174 lymphocyte (CTL) escape mutations within the immunodominant HLA-B57 (Bw4)-restricted Gag epitope TSTL

175 fic differences in antiviral efficacy for an immunodominant HLA-B57-restricted response in controller

176 Viral escape within the immunodominant, HLA-B27-restricted, HCV-specific, cluste

177 allergen, Art v 1, contains only one single, immunodominant, HLA-DR1-restricted epitope (Art v 125-36

178 We have defined the immunodominant, HLA-restricted T-cell epitopes of OprF.

179 We have identified previously unreported immunodominant HSV antigens, among which were 4 ID-A-Ags

180 >98% of CD8(+) T cells are specific for the immunodominant HSV-1 epitope (gBT-I.1).

181 of the primary CD8(+) T cell response to the immunodominant HSV-1 epitope HSV glycoprotein B 495-502

182 uggests that CD8(+) T cells, specific to the immunodominant HSV-1 glycoprotein B (gB) H-2(b)-restrict

183 de vaccine and the rAdv5 vaccine express the immunodominant HSV-2 CD8(+) T cell epitope (gB(498-505))

184 In this study, UV-inactivated HSV1/2 and immunodominant HSV2 glycoprotein D peptides conjugated t

185 eferentially' activated and mobilized within immunodominant human-leukocyte-antigen-(HLA)-A*11:01-res

186 g T-cell receptors (TCRs) that recognize the immunodominant IAV epitope GILGFVFTL (GIL).

187 tide eliciting a stronger response is called immunodominant (ID), and those with smaller-magnitude re

188 tive N-terminal region was identified as the immunodominant IgA epitope.

189 One region in the wing domain of NS1 was immunodominant in both mouse vaccination and human infec

190 rst time, to our knowledge, that the HLA-B27 immunodominant influenza nucleoprotein (NP) 383-391 epit

191 HC individuals after activation with pooled immunodominant islet peptides.

192 action monitoring was used to quantitate the immunodominant K(d)-restricted T-cell epitope islet-spec

193 The observations that immunodominant ligands can be found at lower levels and

194 identified phosphatidylglycerol (PG) as the immunodominant lipid antigen.

195 ) T cells, LLO118 and LLO56, specific for an immunodominant Listeria monocytogenes epitope, with dram

196 Moreover, the functional avidities of the immunodominant M1(58-66)/HLA-A*02:01-specific T cells we

197 oducing CD8(+) T cells were specific for the immunodominant major histocompatibility complex (MHC) cl

198 Deep viral sequencing of the immunodominant Mamu-B*017:01-restricted Nef165-173IW9 ep

199 e recently shown that vaccination with three immunodominant Mamu-B*08-restricted epitopes (Vif RL8, V

200 death-1 (PD-1), but surprisingly, while the immunodominant memory response appeared to be functional

201 lium-specific serum antibodies targeting the immunodominant MgpB and MgpC proteins appeared within 1

202 ation to generate antigenic diversity in the immunodominant MgpB and MgpC proteins.

203 H4- and H60-derived epitopes are known as immunodominant mH-Ags in H2(b)-compatible BALB.B to C57B

204 e of surface expression of SMCY(311-319), an immunodominant minor histocompatibility Ag, as detected

205 ue within an LC3-interacting region motif of immunodominant MOG peptides abrogated their degradation.

206 conversion of destructive processing of the immunodominant MOG40-48 epitope into productive processi

207 synthetic compounds were employed to uncover immunodominant moieties of ECA.

208 spanning the MPO molecule, we identified an immunodominant MPO CD4(+) T-cell epitope (MPO(409-428)).

209 These studies identify an immunodominant MPO T-cell epitope and redefine how effec

210 s B cells to protect a proteolysis-sensitive immunodominant myelin oligodendrocyte glycoprotein (MOG)

211 , comprising a polyrhamnose backbone with an immunodominant N-acetylglucosamine (GlcNAc) side chain,

212 lerance induced by nasal insufflation of the immunodominant nephritogenic MPO peptide (MPO409-428) to

213 existing immunity by constantly altering the immunodominant neutralizing antibody epitopes (antigenic

214 ibody epitopes but limit the presentation of immunodominant non-NAb epitopes that might induce off-ta

215 Viral subunit vaccines often contain immunodominant non-neutralizing epitopes that divert hos

216 ection of costly escape mutations within the immunodominant NS5B KSKKTPMGF epitope may contribute in

217 es with particular epitopes eliciting either immunodominant or subdominant responses after viral chal

218 Specifically, CLL69C bound immunodominant OSE adducts termed MAA (malondialdehyde-a

219 gM recognized ehrlichial Ag(s), including an immunodominant outer membrane protein.

220 mpared with mice that received an irrelevant immunodominant ovalbumin (OVA) peptide, OVA323-339, mice

221 c CD8+ T cell responses directed against the immunodominant p24 Gag-derived epitope KK10 (KRWIILGLNK2

222 An immunodominant peptide (p185(378-394)) derived from the

223 One remarkably promiscuous immunodominant peptide (P9) could be presented by divers

224 e whether DEC205(+) DC targeting of a single immunodominant peptide derived from human cartilage prot

225 HC-peptide dextramer multimers containing an immunodominant peptide derived from HY to identify fetal

226 y which MHC class I (MHC I) molecules sample immunodominant peptide epitopes, however, remains poorly

227 icated that the I-A(b) binding region of the immunodominant peptide of MOG is susceptible to cleavage

228 tic cells, to process and present the I-A(b)-immunodominant peptide of the autoantigen myelin oligode

229 g Foxp3 and HLA-DR1 covalently linked to the immunodominant peptide of the autoantigen type II collag

230 els depend on T cells restricted to a single immunodominant peptide of the immunizing Ag, which does

231 As HLA-DM activity directly favors immunodominant peptide presentation, polymorphisms in HL

232 nsion, with implications for beta-selection, immunodominant peptide recognition, and germ line-encode

233 lymphocytes responsive to a K(b)-restricted immunodominant peptide, FAPGNYPAL (Tet(+)).

234 T cell lines were specific for 15 immunodominant peptides and derived preferentially from

235 The recognized peptides differed from the immunodominant peptides and were part of the best promis

236 ity/high-affinity behavior and its impact on immunodominant peptides in T-cell responses to some infe

237 ivity by EBV led to total degradation of the immunodominant peptides MOG35-55 and MOG1-20 Inhibition

238 es for motility, adhesion, toxin production, immunodominant peptides, and key regulatory molecules, i

239 igen (HLA)-A2 and bioinformatics to identify immunodominant peptides.

240 otein in human cytomegalovirus (HCMV) is the immunodominant phosphoprotein 65 (pp65), which is freque

241 r T cells specific for cytomegalovirus-pp65 (immunodominant protein), tetanus toxoid, measles, mumps,

242 or vaccinia virus and Candida albicans-MP65 (immunodominant protein), typical pathogens of skin and/o

243 Immunodominant proteins encoded by members of the variab

244 peptides used for B-cell epitope mapping of immunodominant proteins of Chlamydia spp.

245 from those of seronegative donors for all 3 immunodominant proteins, Gag, Env, and Tax.

246 Five novel immunodominant proteins-Rv1957, Rv1954c, Rv1955, Rv2022c

247 tigenically distinct lineages defined by the immunodominant receptor binding protein, haemagglutinin.

248 V2, with targeting of fewer epitopes in the immunodominant region of gp41 (gp41-ID) and the V1 regio

249 er peptide sequence covering the core of the immunodominant region of the allergen is a potential tar

250 ggesting that this antigenic domain forms an immunodominant region of the protein.

251 fy the cis-adhesive interface of DSG3 as the immunodominant region targeted by pathogenic antibodies

252 response to foreign epitopes inserted at the immunodominant region, located at the tips of spikes on

253 inserted at two alternative positions in the immunodominant region.

254 vestigate whether T-regs specific for CYP2D6 immunodominant regions and restricted by the appropriate

255 rated that OIT with SP and MP comprising the immunodominant regions of Ovm was safe and significantly

256 Overall, we identified a small number of immunodominant regions, which were in functionally impor

257 the C1, C2, V1, V2, and V3, C4, C5, and gp41 immunodominant regions.

258 of the viruses, and other mice developed an immunodominant response to a normally subdominant, cross

259 Vaccinated volunteers had an immunodominant response to the Gag293 epitope with a fun

260 In BALB/C mice the immunodominant response was shifted from the previously

261 n inhibitory receptor and in contrast to the immunodominant response, which is impaired.

262 e to an adult-like K(d)M282-90 CD8(+) T cell immunodominant response.

263 ce diversity and the propensity of eliciting immunodominant responses targeting variable regions of t

264 asmid DNA (pDNA) vaccine is able to redirect immunodominant responses to otherwise subdominant and of

265 ax is a commixture of a peptide representing immunodominant RSV CD8(+) T cell epitope M282-90, a TLR

266 by competing for HLA-A*02 binding sites with immunodominant scarcely expressed antigenic peptides.

267 cy related (DosR) latency, but not classical immunodominant secretory antigens, to clearly differenti

268 ution of humoral immune responses toward its immunodominant sequences in 90 patients with a range of

269 nize several overlapping epitopes within the immunodominant site.

270 receptor binding or altered epitopes at the immunodominant sites.

271 Immunodominant surface antigen B (IsaB) is a virulence f

272 genome backbones, in which loci that encode immunodominant surface proteins (ompA and pmpEFGH) have

273 to three of these peptide/HLA complexes-the immunodominant SVG9 (E protein), the subdominant SLF9 (N

274 In contrast, immunodominant "symptomatic" antigens (ID-S-Ags) may exa

275 e generated a single protein which contained immunodominant T cell epitopes of the three polypeptides

276 We sought to identify the immunodominant T cell epitopes of tropomyosin, the major

277 panning the whole alpha3IV-NC1 domain, three immunodominant T cell epitopes were identified.

278 The immunodominant T cell peptides identified were then fed

279 Remarkably, immunodominant T cell reactivities were directed against

280 Thus, an immunodominant T cell response can be due to a dominant

281 d, we here characterize the phenotype of the immunodominant T cell responses.

282 e many other major allergens, it contains an immunodominant T cell-activating region (Bet v 1142-156)

283 human B-cell surface receptors (CD19-22) to immunodominant T-cell antigens from EBV proteins, includ

284 5 or greater, affecting presentation of the immunodominant T-cell epitope in vitro.

285 od samples from human donors are identifying immunodominant T-cell epitopes in FVIII and possible tar

286 v 1 homologs correlates with the presence of immunodominant T-cell epitopes.

287 virus and identified F, N, M2-1, M, and P as immunodominant target antigens.

288 ated the T cell responses that recognize the immunodominant Tax protein to the tax sequences present

289 lieving their lysis-dependent suppression by immunodominant TCD8 To our knowledge, our work constitut

290 have explored the energetic basis of how an immunodominant TCR (termed SB27) binds to a 13-amino aci

291 ed CD8+ and/or CD4+ T cell responses against immunodominant TEM1 protein sequences.

292 tect infected host cells >20 hr earlier than immunodominant trans-sialidase-specific T cells.

293 17) show that T cells specific for different immunodominant vaccine antigens can fail to protect for

294 nd structural characterization of one of the immunodominant vaccinia virus (VACV) antigens, D8, and i

295 luenza virus infection or vaccination target immunodominant, variable epitopes on the globular head r

296 o this conserved stem in the presence of the immunodominant, variable head domain of HA is challengin

297 family of Plasmodium falciparum encodes the immunodominant variant surface antigens PfEMP1.

298 The virus escaped from immunodominant Vif and Nef Mamu-B*00801-restricted CD8(+

299 T cells revealed a shift in the hierarchy of immunodominant viral epitopes in virus inoculated mice w

300 n asthmatic subjects, Bla-g 5, 9 and 11 were immunodominant, while, in contrast, nonasthmatic-sensiti