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1 n occurs among clones responding to the same immunodominant determinant.
2 : suppression mediated by TCD8+ specific for immunodominant determinants.
3 detail in mice, CTL typically focus on a few immunodominant determinants.
4 tein Ags have been shown to focus on a few ("immunodominant") determinants.
5 fic CD4(+) and CD8(+)T(M) and independent of immunodominant determinants and functional avidities but
6 nants may be expressed at or above levels of immunodominant determinants, at least on antigen present
7 not only in the loss of response to certain immunodominant determinants, but can also result in a ga
8 gens are capable of inducing T(CD8+) to such immunodominant determinants, but the diversity of the re
9 haracterization of T cells reactive with the immunodominant determinant, CII 607-621, responsible for
13 tion of high avidity clones specific for the immunodominant determinant making that determinant appea
16 n of B10.PL mice with the Ac1-9 peptide, the immunodominant determinant of myelin basic protein (MBP)
17 virus infections, and immunization with the immunodominant determinant provided significant protecti
19 e directed against a single I-Ak- restricted immunodominant determinant, the core of which is peptide
20 lues in TdT-/- mice while responses to three immunodominant determinants undergo a major reshuffling.
22 majority of T(CD8+) respond to one or a few immunodominant determinants, with a minority of T(CD8+)
23 cell response to human CII was focused on an immunodominant determinant within CII263-270 and a minor
25 fferent MHC haplotypes, demonstrate that the immunodominant determinants within HEL are distributed a
26 terogeneity of proliferative response to the immunodominant determinants within hen eggwhite lysozyme
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