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1 rmalized circulating levels of cytokines and immunoglobulin E.
2 mpaired in mastocytosis or allergen-specific immunoglobulin E.
3 r "aptamer" designed to bind specifically to immunoglobulin E.
4 d by T helper type 2 cytokines and increased immunoglobulin E.
5 high levels of interleukin (IL)-5, IL-4, and immunoglobulin E.
6 n 5 in the lung, and reduced serum levels of immunoglobulin E.
7 s to common allergens, which are mediated by immunoglobulin E.
8 rface expression by a 4-d preincubation with immunoglobulin E.
9 lycerides,.37; diastolic blood pressure,.21; immunoglobulin E,.63; lipoprotein(a),.77; and body-mass
12 aggregation of Fc epsilon RI receptors with immunoglobulin E and antigen is mediated through the act
14 asthma phenotypes, such as high total serum immunoglobulin E and bronchial hyperresponsiveness, have
18 -alpha-treated mice exhibited elevated serum immunoglobulin E and inhibition of the anticryptococcal
20 oded nanopores to detect single molecules of immunoglobulin E and the bioterrorist agent ricin, seque
21 h2 response was accompanied by production of immunoglobulin E and the sensitization of circulating ba
22 eutic approaches, including the targeting of immunoglobulin E and tumour necrosis factor alpha with b
23 a mutant deficient in delta-toxin, promoted immunoglobulin-E and interleukin-4 production, as well a
24 amers against a surface-immobilized protein (immunoglobulin E) and a solution-phase small molecule (b
26 Th2 cell skewing was dependent on basophils, immunoglobulin E, and interleukin-4, but was independent
31 at year 1 and repeated assessments of serum immunoglobulin E antibodies (year 1, 4.5, 6), atopic der
32 xpectedly, FcgammaRIV 'preferentially' bound immunoglobulin E antibodies of the 'b' allotype (IgE(b))
33 allergens in home dust samples, and specific immunoglobulin E antibodies were measured at outset, and
34 ex sensitization (measured by latex-specific immunoglobulin E antibodies) by using data from 5,512 ad
36 rotocol including measurement of HE-specific immunoglobulin E-antibodies in serum, skin prick tests,
38 e poor correlation between allergen-specific immunoglobulin E (asIgE) and clinical signs of allergy i
39 fector cells in allergic disorders and other immunoglobulin E-associated acquired immune responses th
40 on as effector and immunoregulatory cells in immunoglobulin E-associated allergic disorders, as well
41 -6, CXCL8), IL-12, CCL11, thromboxane B2 and immunoglobulin E at 24 h after local allergen challenge.
42 RI subunits for the formation of functional, immunoglobulin E-binding FcepsilonRI complexes during en
44 n-specific T-cell responses by internalizing immunoglobulin E-bound antigens for presentation to anti
46 erin ectodomains fused to the Fc fragment of immunoglobulin (E-cad/Fc, N-cad/Fc, and P-cad/Fc) and im
47 measured the motion of fluorescently labeled immunoglobulin E complexed to high affinity receptors (F
48 llergen specificity, allergen-specific serum immunoglobulin E concentration, or individual laboratory
50 +)) influx; however, unlike that mediated by immunoglobulin-E crosslinking, it did not require the sp
51 49B1 is expressed on mast cells and inhibits immunoglobulin E-dependent activation and inflammation i
52 ved in the recruitment of neutrophils during immunoglobulin E-dependent gastric inflammation in the m
54 s can exacerbate ADHD symptoms and cause non-immunoglobulin E-dependent histamine release from circul
56 ond important action of ISS is inhibition of immunoglobulin E-dependent release of Th2 cytokines, esp
59 andard was carried out for allergen-specific immunoglobulin E determination using the fluoroimmunoenz
61 kin tests and measurement of serum levels of immunoglobulin E do not accurately identify foods for el
63 otal immunoglobulin E (TIgE), serum-specific immunoglobulin E, eosinophil count in peripheral blood,
65 ggregation of the high affinity receptor for immunoglobulin E (Fc epsilon RI) on mast cells results i
66 Aggregation of high-affinity receptors for immunoglobulin E (Fc epsilon RI) on the surface of mast
67 aling through the high affinity receptor for immunoglobulin E (Fc epsilon RI) results in the coordina
69 ss-linking of the high-affinity receptor for immunoglobulin E (FcepsilonRI) results in release of inf
72 n mediated by the high-affinity receptor for immunoglobulin E, FcepsilonRI, but the molecular basis i
74 gation of the high-affinity Fc receptors for immunoglobulin E (IgE) (FcepsilonRI) on the surface of m
76 etecting human immunoglobulin G (IgG), human immunoglobulin E (IgE) and Aspergillus fumigatus antibod
77 ory-like', increased serum concentrations of immunoglobulin E (IgE) and caused dendritic cells to pro
78 d candidate genes for association with total immunoglobulin E (IgE) and effect modification by 25-hyd
79 Production of IL-4 and the generation of immunoglobulin E (IgE) and eosinophil responses were pre
81 cells express the high-affinity receptor for immunoglobulin E (IgE) and have been linked to host defe
83 , this treatment increases parasite-specific immunoglobulin E (IgE) and other Th2 responses in the mo
84 s, characterized by increases in total serum immunoglobulin E (IgE) and specific serum IgG1 levels an
88 isdirected type 2 immune responses, in which immunoglobulin E (IgE) antibodies are produced against a
92 nsor, featuring a highly specific anti-human immunoglobulin E (IgE) aptamer as a capture probe, for h
94 he first to report high levels of functional immunoglobulin E (IgE) autoantibodies recognizing brain
97 ), stably cross-links anti-2,4-dinitrophenyl-immunoglobulin E (IgE) bound to high affinity receptors
98 n: FM by plethysmography, total and specific immunoglobulin E (IgE) by automated immunosorbent analys
99 everal extracellular cues, including antigen-immunoglobulin E (IgE) complexes, bacteria, viruses, cyt
101 Framingham Heart Study data on total plasma immunoglobulin E (IgE) concentrations and found a number
102 nts stimulated by the mast cell receptor for immunoglobulin E (IgE) correlated with the affinity of a
106 gths (I) on allergen extractability from and immunoglobulin E (IgE) immunoreactivity of peanut, almon
107 ctivated B lymphocyte increases the level of immunoglobulin E (IgE) in a protein kinase A (PKA)- and
109 n of low concentrations of allergen-specific Immunoglobulin E (IgE) in human sera using a Photonic Cr
110 itative immunoassay for the determination of immunoglobulin E (IgE) in human serum using gold nanoclu
112 high-affinity Fc receptor (FcepsilonRI) for immunoglobulin E (IgE) in MC/9 mouse mast cells stimulat
114 lper (Th) 2 cells, the physiological role of immunoglobulin E (IgE) in the airway remains largely und
119 r-based biosensor for the detection of human immunoglobulin E (IgE) is developed using the electroche
128 study examined the association between serum immunoglobulin E (IgE) levels for a panel of common indo
129 rhinitis, and itchy rash) and serum-specific immunoglobulin E (IgE) levels from the 2005-2006 Nationa
132 ry, maternal and paternal total and specific Immunoglobulin E (IgE) levels, and cord blood IgE were r
133 erresponsiveness (BHR), elevated total serum immunoglobulin E (IgE) levels, and skin tests positive t
134 ed based on increased IL-5 production, total immunoglobulin E (IgE) levels, antigen-specific IgG1 res
135 f intermediate phenotypes, one each on serum immunoglobulin E (IgE) levels, blood eosinophil counts a
140 estigated how the high-affinity receptor for immunoglobulin E (IgE) modulates the response of mast ce
142 acebo-controlled clinical trials of the anti-immunoglobulin E (IgE) monoclonal antibody, rhuMAb-E25 (
143 e current study, we used omalizumab, an anti-immunoglobulin E (IgE) monoclonal antibody, to demonstra
144 basophils that express a particular type of immunoglobulin E (IgE) or IgE+, was found to induce inte
145 ividuals is that parasite-induced polyclonal immunoglobulin E (IgE) out-competes allergen-specific Ig
146 omosome 14q was screened for loci modulating immunoglobulin E (IgE) phenotypes in 15 extended and 45
148 as suggested an increase in antigen-specific immunoglobulin E (IgE) production during viral infection
149 draining lymph node (DLN) cell infiltrates, immunoglobulin E (IgE) production, and airway hyper-resp
150 igated the relationship between the specific immunoglobulin E (IgE) profile for 40 allergens using a
155 and basophils that express the high-affinity immunoglobulin E (IgE) receptor, Fc epsilon receptor 1 (
159 by which allergic patients develop specific immunoglobulin E (IgE) responses to environmental allerg
160 he basis of immune deviation that results in immunoglobulin E (IgE) sensitization and allergic reacti
161 ociated with concomitant atopic diseases and immunoglobulin E (IgE) sensitization to food allergens i
162 gher baseline levels of schistosome-specific immunoglobulin E (IgE) than did children with > or =2 re
164 s in the allergic reaction is the binding of immunoglobulin E (IgE) to its high affinity receptor (Fc
165 s is reported for the sensitive detection of immunoglobulin E (IgE) using fluorescence polarization (
166 isease and asthma, and more than 30 yr since immunoglobulin E (IgE) was identified as the key molecul
167 nce and binding properties of an aptamer for immunoglobulin E (IgE) was investigated using custom DNA
168 ns at the site of infection and infection of immunoglobulin E (IgE)(-/-) mice, lead us to suggest tha
170 CD4-CD8- peripheral T cells, elevated serum immunoglobulin E (IgE), and possible pulmonary inflammat
171 markers of Th2 inflammation, reducing serum immunoglobulin E (IgE), chemokine ligands 13 and 17 by a
172 r, the level of a systemic Th2 marker, serum immunoglobulin E (IgE), correlated significantly with SR
173 cells by phosphorylation of the receptor for immunoglobulin E (IgE), FcepsilonRI, by Lyn kinase after
174 g by antigen, the high affinity receptor for immunoglobulin E (IgE), FcepsilonRI, is phosphorylated b
175 y fever, allergic sensitization, serum total immunoglobulin E (IgE), forced expiratory volume in one-
176 of allergens, and geometric mean serum total immunoglobulin E (IgE), in 3451 participants aged 18-75
178 The distinguishing structural feature of immunoglobulin E (IgE), the antibody responsible for all
179 We identified unique signatures for AD (Immunoglobulin E (IgE), thymus- and activation-regulated
181 f LPA were functional, as evidenced by their immunoglobulin E (IgE)-dependent histamine release and b
183 an emphasis on novel FcepsilonRI regulators, immunoglobulin E (IgE)-independent pathways [e.g., Mas-r
186 ldhood asthma are associated with atopy, the immunoglobulin E (IgE)-mediated familial syndrome of all
189 a consequence of antigen-aggregation of the immunoglobulin E (IgE)-occupied high affinity receptor f
196 nsitivity (DTH) to SEA; high levels of serum immunoglobulin E (IgE); a strong T2 cytokine phenotype w
199 tood, the disease is mediated by an abnormal immunoglobulin-E immune response in the setting of skin
201 complete lack of prevailing Sm-p80-specific immunoglobulin E in a high-risk or infected population w
203 gen-specific serum immunoglobulins and total immunoglobulin E in different groups of animals were mea
205 sis in the jejunum and had reduced ovalbumin-immunoglobulin E in their serum, compared with TSLPR(+/+
206 These studies highlight a mast cell- and immunoglobulin E-independent role for CCR6-bearing T cel
207 essential role in antigen sensitization and immunoglobulin E induction, stimulate dendritic cell acc
208 Also, substantial reductions in plasma total immunoglobulin E, interleukin (IL)-1beta, and tumor necr
211 rd the T helper 2 type, with increased total immunoglobulin E levels (P<.06) and a tendency toward in
212 OVA-specific Th1 to Th2 cells and decreased immunoglobulin E levels after allergen challenge as adul
213 antigen treatments resulted in reduced total immunoglobulin E levels and peripheral blood eosinophil
214 g doxorubicin and trastuzumab, high baseline immunoglobulin E levels are associated with a lower risk
215 tions between multiple VDR polymorphisms and immunoglobulin E levels were also observed (p = 0.006-0.
216 l alkaline phosphatase (PLAP) and polyclonal immunoglobulin E levels were also quantified in paired m
217 h doxorubicin and trastuzumab, high baseline immunoglobulin E levels were associated with a significa
219 4 production by NKT cells, to increase serum immunoglobulin E levels, and to promote the generation o
220 urrent viral and bacterial infections, hyper-immunoglobulin E levels, eczema, and greater susceptibil
221 allenge with ovalbumin, as measured by total immunoglobulin E levels, ovalbumin-specific immunoglobul
223 iotemporal dynamics of the redistribution of immunoglobulin E-loaded receptors (IgE-FcepsilonRI) on r
224 etion of cytokines involved in regulation of immunoglobulin E, mast cells, basophils and eosinophils,
225 lower immunoglobulin A (median, 1:3,200) and immunoglobulin E (median, 1:128) titers to rAls3p-N by e
229 tive incidence to be 0.34% by 1 year of age; immunoglobulin E-mediated cow's milk allergy was 0.5%.
230 f the information available still relates to immunoglobulin E-mediated food reactions, although other
233 rvoir after antigen capture through specific immunoglobulin E molecules bound to their FcepsilonRI.
235 FcepsilonRI, the high-affinity receptor for immunoglobulin E, on RBL-2H3 mast cells results in its c
238 y enhanced type 2 responses (IL-4, IL-5, and immunoglobulin E production) upon in vitro TCR stimulati
239 mal allergen-induced airway hyperreactivity, immunoglobulin E production, mucus metaplasia, and airwa
242 sera from soybean-sensitive individuals have immunoglobulin E reactivity to abundant storage proteins
244 these cells, cross-linking the high-affinity immunoglobulin E receptor (FcepsilonR1) leads to activat
249 lso showed functional defects; high-affinity immunoglobulin E receptor-mediated degranulation was sig
250 tive [Lin-]/CD34hi/CD117int/hi/high-affinity immunoglobulin E receptor-positive [FcepsilonRI+]), with
251 stematic effort to determine the features of immunoglobulin E-receptor (IgE-Fc epsilon RI) aggregatio
253 (IL)-4 and IL-5 and posttreatment levels of immunoglobulin E recognizing the parasite's tegument (Te
254 Robert L. Coffman recounts how his work on immunoglobulin E regulation along with data from Tim Mos
255 duce iBALTs, which coincided with subsequent immunoglobulin E responses, and IL-1-receptor-deficient
257 d treatments of asthma, rhinitis and eczema; immunoglobulin E sensitization; weight; and height.
258 disease, which is frequently associated with immunoglobulin-E sensitization to ubiquitous fungi, typi
259 ences in the number of sensitizations, total immunoglobulin E serum levels and predilection of the sk
260 termined by skin prick tests (SPT); specific immunoglobulin E (sIgE) titers against 12 common allerge
261 to analyze the diagnostic value of specific immunoglobulin E (sIgE) to Gly m 2S albumin, Gly m 4, 5,
262 e, history, skin prick test, peanut specific immunoglobulin E (sIgE), and total IgE minus peanut sIgE
264 efit from targeted anti-interleukin and anti-immunoglobulin E therapies, and in monitoring subsequent
267 hacholine (MTCH)-challenge test, serum total immunoglobulin E (TIgE), serum-specific immunoglobulin E
268 immunoglobulin E levels, ovalbumin-specific immunoglobulin E titers, and eosinophil content of bronc
272 re added, with oral corticosteroids and anti-immunoglobulin E treatment with omalizumab for the most
274 in serum antigen-specific immunoglobulin G1/immunoglobulin E using ovalbumin or Aspergillus fumigatu
275 d gel-phase membranes displaying ligands for immunoglobulin E, using total internal reflection fluore
278 kers of oxidative stress, thromboxane B2 and immunoglobulin E were measured in bronchoalveolar lavage
279 alloproteinase-9 total, apolipoprotein E and immunoglobulin E--were used along with co-variates in mu
280 t differences between cases and controls was immunoglobulin E, with higher levels detected at baselin
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