ライフサイエンスコーパス: immunoglobulin isotype

1 ibody maturation and expression of different immunoglobulin isotypes.

2 lasma cells in vivo, without affecting other immunoglobulin isotypes.

3 center formation and production of secondary immunoglobulin isotypes.

4 proliferate and to switch from IgM to other immunoglobulin isotypes.

5 or to mucosal immunization can influence the immunoglobulin isotype and specificity of the host humor

6 ) is the predominant M. catarrhalis-specific immunoglobulin isotype and that the sputum IgA contains

7 ing with significant increased levels of all immunoglobulin isotypes and anti-DNA antibodies in serum

8 e Th2-type pattern as judged by the ratio of immunoglobulin isotypes and interleukin-4 cytokine level

9 ct was associated with reduced TH2-dependent immunoglobulin isotypes and markedly diminished neutrali

10 acterized by impaired production of switched immunoglobulin isotypes and normal or elevated IgM level

11 effect on the primary induction of anti-CpsB immunoglobulin isotypes and on the ability to induce ant

12 pectra of plasma cells producing the various immunoglobulin isotypes, and the frequencies of virus-sp

13 widespread variation in the levels of serum immunoglobulin isotypes as well as in the percentages an

14 feration and a selective loss of IL-4-driven immunoglobulin isotypes both in vivo and in vitro.

15 at ICOS-/- mice exhibit profound deficits in immunoglobulin isotype class switching, accompanied by i

16 The kinetics, magnitude, and immunoglobulin isotype distribution of the ASC responses

17 Assessment of plasmablast immunoglobulin isotype distribution revealed increased I

18 As well as classically defined switched immunoglobulin isotype-expressing B cells, memory B cell

19 This shift in immunoglobulin isotype had no effect on the host's abili

20 Here, we show that, unlike other immunoglobulin isotypes, human IgG2 (h2) imparts Fcgamma

21 factors such as M protein concentration and immunoglobulin isotype, identify a group of individuals

22 among the 10 most dominant BCR clones of any immunoglobulin isotype (IgA, IgD, IgM, and IgG) in blood

23 baseline levels of the Th2-controlled serum immunoglobulin isotypes, IgE and IgG1, were also selecti

24 ounced dominance of secretory IgA over other immunoglobulin isotypes in human saliva, tears, milk, an

25 alysis was used to study the distribution of immunoglobulin isotypes in paired preacquisition and pos

26 onsequences of a lack of production of other immunoglobulin isotypes in patients with HIgM syndrome.

27 The role of other immunoglobulin isotypes in the birch pollen-plant food s

28 re deficiency in the production of secondary immunoglobulin isotypes including IgG1, IgG2a, IgG2b, Ig

29 observation suggests that specialization of immunoglobulin isotypes into mucosal and systemic respon

30 5 g/dL), and reduction of 1 or 2 noninvolved immunoglobulin isotype levels (immunoparesis).

31 Of note, IgG is the predominant immunoglobulin isotype of plasmablasts that arise transi

32 The predominant immunoglobulin isotype of these autoantibodies was immun

33 ing that paradigm, here we show that IgT, an immunoglobulin isotype of unknown function, acts like a

34 Additional immunoglobulin isotypes of identical V(H)DJ(H) sequence

35 d this heterogeneity cannot be attributed to immunoglobulin isotypes or affinity for CTLA-4.

36 regulation of T(H)2 responses, IL4-dependent immunoglobulin isotype production, and tissue lesions wi

37 induction of primary and secondary anti-CpsB immunoglobulin isotype profiles were studied.

38 Hemagglutination inhibition and immunoglobulin isotype profiling indicated that DBA.2 an

39 Immunoglobulin isotyping revealed that the vaccination p

40 s coordinates the immune response, including immunoglobulin isotype switch and Fas-mediated apoptosis

41 responses, B cells are driven to undergo an immunoglobulin isotype switch, shifting from IgM to IgE

42 analyses confirmed the known role of AID in immunoglobulin isotype switching and also demonstrated f

43 Moreover, in the transgenic mice both immunoglobulin isotype switching and germinal center for

44 IgM syndrome) is characterized by failure of immunoglobulin isotype switching and severe defects of c

45 B cells have undergone comparable levels of immunoglobulin isotype switching and somatic hypermutati

46 feration and guide their differentiation and immunoglobulin isotype switching by delivering contact-d

47 How the magnitude of immunoglobulin isotype switching is controlled is still

48 per-IgM (HIGM1), characterized by failure of immunoglobulin isotype switching, is caused by mutations

49 or lipopolysaccharide/interleukin-4-mediated immunoglobulin isotype switching.

50 togenesis, T-helper cell differentiation and immunoglobulin isotype switching.

51 r B-cell proliferation, differentiation, and immunoglobulin isotype switching.

52 To determine the importance of the immunoglobulin isotypes that are transported into the in

53 f expressing surface IgM and secreting other immunoglobulin isotypes were vulnerable to lethal infect

54 typical HCL, all expressing multiple surface immunoglobulin isotypes, were analyzed.

55 ntibody activity is associated with a unique immunoglobulin isotype, which is now called IgE.