ライフサイエンスコーパス: immunologically

1 Four children were evaluated clinically and immunologically.

2 jugates were characterized biochemically and immunologically.

3 and has never to our knowledge been studied immunologically.

4 's own cells, facilitating the generation of immunologically acceptable stem cell-based therapeutics.

5 settings (RLSs) is monitored clinically and immunologically, according to World Health Organization

6 ammatory mediator secretion were measured in immunologically activated cultured mast cells derived fr

7 evident with endogenous cysLTs produced from immunologically activated mast cells because inhibition

8 The low quantities of immunologically active allergens transferred through bre

9 ed between the antibody, ARM-H, and gp120 is immunologically active and leads to the complement-media

10 gen inoculation directly into the dermis, an immunologically active area containing abundant dendriti

11 f both T cells and B cells, as well as other immunologically active cells, including mast cells, than

12 mal number of recombinant enzymes to produce immunologically active CPSA, we cloned the genes csaA, c

13 In addition, increasing knowledge on the immunologically active factors in breast milk have also

14 ransmission may be caused by the presence of immunologically active factors, including human milk oli

15 of age, 475 participants received 100 mg of immunologically active gluten daily, and 469 received pl

16 PreventCD protocol, infants received 100 mg immunologically active gluten/d or placebo from 4 to 6 m

17 carriage, including how GBS persists in this immunologically active host niche long term, are not wel

18 , providing a noninvasive method to identify immunologically active microenvironments in secondary br

19 osts and facilitate the determination of the immunologically active molecular components.

20 terial vesicles are a delivery mechanism for immunologically active molecules that contribute to myco

21 in an all-or-nothing manner, existing in an immunologically active or inactive state.

22 o a minor extent in O-4) position results in immunologically active polymer.

23 members of an E3 family that regulates other immunologically active proteins.

24 p time (as a continuous variable) among more immunologically active recipients (those having more ris

25 aling facilitated conversion of tumors to an immunologically active tumor microenvironment with incre

26 Adipocytes have been suggested to be immunologically active, but their role in host defense i

27 It is now appreciated that the brain is immunologically active.

28 te and that antiretroviral therapy (ART) for immunologically advanced disease is associated with subs

29 rmine the effects on transmission or in less immunologically advanced disease.

30 to reduce allergic responses clinically and immunologically after an environmental allergen challeng

31 Furthermore, immunologically, all CsA treated animals responded simil

32 g Treg depletion with anti-Gr-1 antibody was immunologically and clinically more efficacious than ant

33 s and influence the ability of Abeta to form immunologically and morphologically distinct amyloid str

34 cally, physiologically, histopathologically, immunologically and reproductively normal.

35 were recombinantly produced in insect cells, immunologically and structurally characterized, and thei

36 oteins were characterized physicochemically, immunologically, and in in vivo models with or without a

37 s in the colon and that the balance of these immunologically antagonistic cell types is dictated by m

38 Current detection assays are immunologically based and require cumbersome antibody im

39 measurement with traditional methods such as immunologically based assays.

40 f mucin in CF sputum is low when measured by immunologically based techniques, and mass spectrometric

41 ndolent non-Hodgkin lymphoma with a focus on immunologically based therapies.

42 Patients were evaluated clinically and immunologically before and after 4, 8, and 24 weeks of t

43 tion and subsequent sepsis may be controlled immunologically by the intervention of M2bM present in M

44 c proteins assembled into VLPs were verified immunologically by their reactivities with a conformatio

45 aracterized biochemically, structurally, and immunologically by using sera from patients with CD and

46 le Tumour cell-line database, a cell bank of immunologically characterised melanoma cell lines.

47 The goal of this study was to develop and immunologically characterize 3 murine models of ASIT to

48 We sought to identify and immunologically characterize the allergenic components o

49 The aim of this study was to clinically and immunologically characterize these patients with EoE-lik

50 Here, we immunologically characterized 3 patients with de novo ac

51 le Tumour Cell-Line Database, a cell bank of immunologically characterized melanoma cell lines.

52 ichia canis, including three molecularly and immunologically characterized pairs of immunoreactive ta

53 small simian model of chronic HBV infection, immunologically close to humans, that should be most val

54 d that secondary-progressive MS patients are immunologically closer to relapsing-remitting patients a

55 standing IDO inhibitors as adjuvants to turn immunologically 'cold' tumors 'hot' can seed new concept

56 The participation of an immunologically compatible donor-intended recipient pair

57 Platelets are immunologically competent cells containing cytokines suc

58 combinations of relatively small numbers of immunologically complementary Env trimers may improve nA

59 Colorectal cancer originates within immunologically complex microenvironments.

60 These mutants are starvation sensitive, immunologically compromised and short-lived, all phenoty

61 The sarcomas are transplantable to immunologically compromised hosts, showing that they are

62 auses significant morbidity and mortality in immunologically compromised individuals, such as bone ma

63 ry different forms: those that are typically immunologically contained after acute symptomatic infect

64 ability of an effective vaccine based on the immunologically cross-protective vaccinia virus.

65 s highlight the potential importance of this immunologically cryptic neutralizing epitope from PA as

66 or microenvironment (TME) also represents an immunologically desirable strategy for reversing immunos

67 barrier that regulates the fly's ability to immunologically detect and respond to the presence of th

68 s, several publications show that GSH is not immunologically detectable in outer segments of rod and

69 ns carried the pga locus, 25 of 30 expressed immunologically detectable PNAG, and 21 of 30 could be k

70 sed concentrations of urinary EVs containing immunologically detectable podocyte-specific proteins by

71 liac disease and pyoderma gangrenosum may be immunologically different.

72 Here, we review how the CNS immunologically discriminates between pathogens and ster

73 rtant minor blood-group antigen that has two immunologically distinct alleles, referred to as Fy(a) o

74 to sex differences in susceptibility to two immunologically distinct disease models, experimental au

75 virus type 1 (HTLV-1) is associated with two immunologically distinct diseases: HTLV-1-associated mye

76 studies showed that AAbeta1AR and AAM2R were immunologically distinct from TSHR antibodies.

77 ng data show that prior immunization with an immunologically distinct hemagglutinin of the same subty

78 ved from lungs of 2 clinically relevant, but immunologically distinct murine models of IPA on days 2

79 rlapping cytoskeletal activities can utilize immunologically distinct pathways to achieve synonymous

80 by Clostridium botulinum and exist as seven immunologically distinct serotypes designated A through

81 y fabricated sensors were incubated with two immunologically distinct serotypes of Ad, Ad5 and Ad3, w

82 The seven immunologically distinct serotypes of BoNTs (A-G), each

83 This leads to the rise of immunologically distinct strains of the same genotype on

84 Recent evidence indicates that several immunologically distinct structural variants exist as fo

85 To investigate whether microbiologically and immunologically distinct subsets of patients with HIV an

86 as suggestive evidence for the existence of immunologically distinct subsets of subjects with a demy

87 Existence of two immunologically distinct types of apoptotic blebs may pr

88 ew properties of RNA therapeutics, which may immunologically distinguish them from their endogenous c

89 ) clamps using B28-Asp insulin that could be immunologically distinguished from endogenous insulin.

90 us function and reduce inflammation in three immunologically diverse mouse models of inflammatory dis

91 -cell stimulation and benefit the ability of immunologically diverse populations to be effectively va

92 In four immunologically diverse, murine disease models, characte

93 re effective vaccines but are chemically and immunologically diverse, resulting in a major barrier to

94 DENV-1 was immunologically dominant in both monovalent and tetraval

95 ffecting protection with the intertwined and immunologically driven tissue damage.

96 tis with/without asthma were treated with an immunologically enhanced SCIT formulation (AVANZ, ALK, D

97 onvenient updosing schedules, a fast updosed immunologically enhanced SCIT formulation has been devel

98 Fast updosed immunologically enhanced SCIT with an optimized allergen

99 vealed to be a highly stable, monomeric, and immunologically equivalent of its natural counterpart.

100 tuberculosis infection limits expression of immunologically essential transcription factors.

101 We designed, synthesized, and immunologically evaluated a number of fully synthetic ne

102 a pruritic dermatitis that is clinically and immunologically extremely similar to human AD.

103 support a benefit from identifying patients immunologically failing first-line ART at 48 weeks.

104 ory molecules on uterine cells to provide an immunologically favorable environment for survival of th

105 We show that conditions for an immunologically fertile environment are met when TGF-bet

106 nity immune responses of limited duration in immunologically fit individuals and disappointing result

107 g in utero development imprints tolerance to immunologically foreign non-inherited maternal antigens

108 B28-Asp-insulin (which can be distinguished immunologically from endogenous insulin) that raised ins

109 om ES cells ectopically expressing HOXB4 are immunologically functional, opening up new opportunities

110 To determine sites of JCV persistence in immunologically healthy individuals.

111 hology at the University of Kentucky from 12 immunologically healthy patients between February 9, 201

112 Immunosuppression for immunologically high-risk renal transplant patients usua

113 acrolimus maintenance monotherapy is safe in immunologically high-risk renal transplant patients.

114 chistosomes maintain their longevity in this immunologically hostile environment is unknown.

115 hat exhibit high mutation rates and exist in immunologically hostile environments.

116 Further work is required to determine immunologically how HLA disparity between mother and fat

117 h the polypeptide chains are organized in an immunologically identical conformation.

118 tamine prior to H. capsulatum infection were immunologically impaired, with increased fungal burden,

119 ent, immunosuppressed, immunocompromised, or immunologically impaired.

120 including Bacteroides fragilis, a common and immunologically important commensal.

121 parasite genotype induced the expression of immunologically important genes, including antimicrobial

122 To characterize this immunologically important interaction, we used monoclona

123 c emigrants (RTEs) comprise a clinically and immunologically important T cell population that indicat

124 Many TRIM proteins are upregulated by the immunologically important Type I and Type II interferons

125 we investigated its ability to rescue these immunologically impotent cells.

126 ls engineered to secrete GIFT4 were rejected immunologically in a B-cell-dependent manner.

127 concentration cannot be accurately measured immunologically in proteolytically active CF secretions;

128 lid and effective solution for patients with immunologically incompatible donors even in the context

129 transplantation enables many recipients with immunologically incompatible donors to be transplanted w

130 because the infecting prion source has been immunologically indistinguishable from normal cellular p

131 IL-1beta may explain why uromodulin remains immunologically inert inside the luminal compartment of

132 suggest that although melanin as such is an immunologically inert material, it confers virulence by

133 -self stem cells should not be considered as immunologically inert or exclusively immunosuppressive i

134 clude that (i) the B. anthracis spore is not immunologically inert, (ii) the exosporium masks epitope

135 Melanin as such was immunologically inert; however, deletion mutant conidia

136 thought that synthetic PEGylated lipids were immunologically inert; however, it's been observed that

137 y and increased susceptibility to colitis in immunologically intact hosts.

138 ubunit of the pyruvate dehydrogenase complex immunologically intact into apoptotic bodies, forming an

139 e, spontaneously metastatic breast cancer in immunologically intact mice, tumor-derived MIF promotes

140 reviously demonstrated that BECs translocate immunologically intact PDC-E2 to apoptotic bodies and cr

141 d causes among elite controllers to those of immunologically intact persons with medically controlled

142 can replicate and cause AIDS-like disease in immunologically intact rhesus macaques without requiring

143 al enzymes, and four nuclear antigens remain immunologically intact with respect to postapoptotic tra

144 rify the mechanism of HHV-6 reactivation, we immunologically investigated peripheral blood mononuclea

145 ause latently infected cells are long-lived, immunologically invisible, and may undergo homeostatic p

146 Immunologically, lack of CD27 expression was associated

147 viral oncogene required for transition from immunologically less responsive type I and type II laten

148 also suggest sunburn and NMSC etiologies are immunologically linked.

149 1 targets multiple genes associated with the immunologically localized disease form, providing an eff

150 h equal renal function and graft survival to immunologically lower risk recipients.

151 odel genetic blood diseases, and manufacture immunologically matched cells for transfusion and cancer

152 Immunologically-matched, induced pluripotent stem cell (

153 The mechanisms involved include immunologically mediated activation of platelets and end

154 a profoundly dangerous, potentially lethal, immunologically mediated adverse drug reaction to unfrac

155 both, disease pathogenesis is thought to be immunologically mediated and there have been numerous re

156 ow that mitochondrial STAT3 is essential for immunologically mediated degranulation of human and mous

157 PDH is essential for immunologically mediated degranulation of mast cells.

158 llergic in nature, with drug allergies being immunologically mediated DHRs.

159 with chronic ulcerative stomatitis, an oral immunologically mediated disease.

160 y revolutionary approach to the treatment of immunologically mediated diseases.

161 nsitivity are diverse, ranging from primary, immunologically mediated disorders of photosensitivity t

162 and HCV are noncytopathic viruses and, thus, immunologically mediated events play an important role i

163 d provide a rational basis for an effective, immunologically mediated inhibition of the formation of

164 y indicate that a common TLR3 allele confers immunologically mediated protection from HIV-1 and sugge

165 Immunologically mediated type B ADRs, such as drug hyper

166 tter predict patient populations at risk for immunologically mediated type B ADRs.

167 ection of MUC1/sec-expressing tumor cells is immunologically mediated, as, initially, innate cells an

168 a viremia is resolving and are thought to be immunologically mediated.

169 tral nervous system and one indirect, likely immunologically mediated.

170 rtality from early ART in the COAT trial was immunologically mediated.

171 to drug-free long-term survival in maximally immunologically mismatched swine.

172 allogeneic CDC transplantation in rats from immunologically-mismatched inbred strains.

173 lish a correlation between pH sensitivity of immunologically modified nano-scaled field-effect transi

174 The potential of effector CD4 T cells to immunologically modulate SIV/HIV infection likely is lim

175 ory and Treg recruitment functions, so as to immunologically monitor the allospecific regulation afte

176 on of cockroach allergen by means of SCIT is immunologically more active than SLIT, especially with r

177 I, suggesting that recently acquired LTBI is immunologically more similar to tuberculosis than remote

178 The disease clinically and immunologically most similar to smallpox is monkeypox, a

179 al animal studies test influenza vaccines in immunologically naive animal models, even though the res

180 rogated in 40 transplant recipients who were immunologically naive before their failed transplantatio

181 s likely to develop respiratory disease than immunologically naive dogs (P < 0.001).

182 odulatory properties of progestins protected immunologically naive female mice from the severe outcom

183 After influenza A infection of immunologically naive ferrets with various H1N1 or H3N2

184 ifficulty in producing a vaccine in a young, immunologically naive host.

185 lasma and Ehrlichia cause acute infection in immunologically naive hosts and are major causes of tick

186 sly been associated with severe infection in immunologically naive hosts, are rarely activated, howev

187 All other age groups (except immunologically naive infants) were likely partially pro

188 Influxes of immunologically naive juvenile fish through recruitment

189 optively reconstituted with splenocytes from immunologically naive mice, we examined the immune respo

190 The absence of prior infections may put an immunologically naive population at risk for disease out

191 o rural populations, spread widely in young, immunologically naive populations (leading to outbreaks

192 ance with high potential to spread into new, immunologically naive populations.

193 nd Chikungunya viruses can spread rapidly in immunologically naive populations.

194 vo fitness on viruses in the newly infected, immunologically naive recipient.

195 Since then, the population that is immunologically naive to orthopoxviruses has increased s

196 obal concern because the human population is immunologically naive to them.

197 virus was compared with that of Dengue virus immunologically naive vaccinees.

198 In the real world, mice and men are not immunologically naive, having been exposed to numerous a

199 so virulent, and the European population so immunologically naive, that the epidemic killed indiscri

200 Immunologically, natural killer cells had an immature ph

201 t have been irradiated and transplanted with immunologically normal bone marrow from either MIA or co

202 Avidity to an immunologically novel GII.4 strain VLP correlated with p

203 s study, we employed DNA vaccination with an immunologically optimized mouse melanoma-shared Ag, Trp1

204 ecific immunoregulatory mechanisms create an immunologically permissive environment for tumor coloniz

205 Immunologically, PLGA-KAg vaccine irrespective of not si

206 frequent, and though insulin can be used to immunologically prevent diabetes of NOD mice, insulin-ba

207 Brain death (BD) can immunologically prime the donor organ and is thought to

208 t oropharyngeal delivery of low-dose LPS can immunologically prime the lung to augment alveolar macro

209 The eye is an immunologically privileged and profoundly immunosuppress

210 disease to occur, these cells must enter the immunologically privileged CNS through a breach in the r

211 une responses to antigen within the normally immunologically privileged cornea.

212 Invasion of immunologically privileged erythrocytes provides a relat

213 egory of self-antigens expressed normally in immunologically privileged mucosal compartments and univ

214 The immunologically privileged nature of the cornea results

215 The eye is an immunologically privileged organ whose Ags serve as targ

216 to the traditional view that the brain is an immunologically privileged site shielded behind the bloo

217 The CNS is often thought of as an immunologically privileged site that fosters replication

218 Immune responses are tempered in immunologically privileged sites including the testis.

219 is the main EAV tissue reservoir rather than immunologically privileged tissues (i.e., testes).

220 scAbs may be restricted from entry into the "immunologically privileged" CNS.

221 e central nervous system has been considered immunologically privileged.

222 inflammatory assault by being located in an immunologically "privileged" niche.

223 remaining proliferating parasites located in immunologically protected sites such as the fetal brain.

224 le of tolerating CNI withdrawal by targeting immunologically quiescent kidney transplant recipients.

225 ession, including those who are deemed to be immunologically quiescent on the basis of current clinic

226 ity and in vitro enzymatic activity and were immunologically reactive against a panel of anti-CNF1 mo

227 5(-/-) dnTGFbetaRII mice, histologically and immunologically, reflect key features of PBC, providing

228 lso caused cardiac teratomas, but these were immunologically rejected after several weeks, in associa

229 nct clinical trajectories, some of which are immunologically related and others which follow patholog

230 ajor role of these loci in the regulation of immunologically related mechanisms.

231 FOs are immunologically related to fibrils because they react wi

232 antibodies promotes the degradation of both immunologically relevant and irrelevant MHC-II molecules

233 Discovery of immunologically relevant antigens in prostate cancer for

234 vival and function was evaluated in vitro in immunologically relevant assays and in vivo in allogenic

235 Polysaccharides are essential and immunologically relevant components of bacterial cell wa

236 o-stage technique generates large numbers of immunologically relevant DCs under near-physiological co

237 We aimed to combine immunologically relevant epitopes of Bet v 1 and the 2 c

238 ed tumor-infiltrating lymphocytes (TILs) and immunologically relevant genes in the neoadjuvant GeparS

239 The L. loa genome encodes many immunologically relevant genes, as well as protein kinas

240 older individuals that were homozygous at an immunologically relevant genetic locus.

241 These findings mechanistically link an immunologically relevant genetic risk factor with a func

242 ng disease cohorts, we established that this immunologically relevant genetic variation in the promot

243 long with accompanying functional assays and immunologically relevant information.

244 lass II and CD28-B7 interactions, we defined immunologically relevant interactions as those >/=500 s.

245 AFM, using tips functionalized with immunologically relevant molecules, can map epitopes of

246 and by increasing the surface expression of immunologically relevant receptors, including class II M

247 n and studied for decades, its role in other immunologically relevant scenarios, including bacterial

248 We consider the immunologically relevant, yet epidemiologically largely

249 ental evidence indicates that stem cells are immunologically responsive cells that home to sites of i

250 cated that human vaginal and cervical EC are immunologically responsive to M. genitalium and to purif

251 Granulomas physically contain and immunologically restrain bacteria that cannot be cleared

252 These results show that TIM-4 and TIM-1 are immunologically restricted members of the group of recep

253 y for sexually transmitted infections, is an immunologically restrictive tissue that prevents entry o

254 king cessation, but a reliably effective and immunologically safe vaccine remains to be identified.

255 third and final phase of the process, where immunologically sculpted tumours begin to grow progressi

256 he HIV envelope has evolved a dense array of immunologically "self" carbohydrates that efficiently pr

257 t nonetheless dramatically depletes multiple immunologically significant commensal bacteria.

258 Early colonization by immunologically silencing microbiota may thus preclude a

259 As compared to Lpn, Llo is immunologically silent and fails to trigger the producti

260 the ability of commensal bacteria to remain immunologically silent and in turn provide pathogen prot

261 sis-driven rational design of highly potent, immunologically silent and stable siRNAs suitable for th

262 n, and hence, cell-death forms disjunct from immunologically silent apoptosis are, in theory, more li

263 iminate a pool of long-lived cells harboring immunologically silent but replication-competent proviru

264 phages share characteristics compatible with immunologically silent clearance of ACs; such characteri

265 The immunologically silent clearance of apoptotic cells is c

266 e signals and how these relate to prompt and immunologically silent clearance of apoptotic cells.

267 The quick, efficient, and immunologically silent disposal of the dying cells requi

268 clearance of NETs and that this occurs in an immunologically silent manner.

269 determines whether mitochondria initiate an immunologically silent or a proinflammatory type of cell

270 developmental switch to a more invasive and immunologically silent phenotype.

271 rapid form of phagocytosis that produces an "immunologically silent" clearance of the apoptotic cells

272 Llo is immunologically silent, highly virulent, and lethal.

273 d, monophosphorylated lipid A in addition to immunologically silent, nonphosphorylated lipid A, they

274 lls trigger inflammatory responses or remain immunologically silent.

275 functions to render mitochondrial apoptosis immunologically silent.

276 totic cell death and may serve to provide an immunologically-silent window by generating specific "fi

277 expression of Ag presenting machinery in an immunologically specialized compartment like the CNS.

278 and an IgG control antibody, gave potent and immunologically specific activities in vitro and in vivo

279 Among immunologically stable patients who underwent transplant

280 iduals in this study being virologically and immunologically stable.

281 Although NA is immunologically subdominant to HA, and clinical studies

282 spectively while receiving virologically and immunologically successful first-line HAART, the number

283 These findings may explain why the LAIV is immunologically superior and offers immediate protection

284 hildren will result in a large population of immunologically susceptible persons who will be at risk

285 unity was contingent on two nonredundant but immunologically synergistic p53-dependent processes: rev

286 ntified significantly more zebras responding immunologically to anthrax than have previous studies us

287 of agents targeting telomerase directly and immunologically to phase III clinical trials.

288 y and on beta function, mass, and insulin in immunologically tolerant anti-CD3 monoclonal antibody (m

289 The liver maintains an immunologically tolerant environment as a result of cont

290 est the hypothesis that nonresponders may be immunologically tolerant.

291 in vivo and whether allogeneic ES cells were immunologically tolerated.

292 ile tolerated well during development and in immunologically unchallenged animals, impairs the expans

293 that the N-terminal two-thirds of BoNT/H is immunologically unique.

294 Immunologically, we noted hypogammaglobulinemia with ter

295 Immunologically, we observed significant increases in th

296 ess viral proteins including LMP2, which are immunologically "weak" but may nonetheless be targets fo

297 The 3 phenotypes were immunologically well discriminated by means of microarra

298 by pulmonary immune effector cells and were immunologically well tolerated by lung tissues.

299 CLB present in bovine hair samples competes immunologically with alkaline phosphatase (AP) enzyme-la

300 omatography-mass spectrometry (LC-MS/MS) and immunologically with monoclonal antibody E06.