ライフサイエンスコーパス: immunomodulatory

1 beta-HSD1 shapes endogenous GC action and is immunomodulatory.

2 olinium-enhancing lesions and was favourably immunomodulatory.

3 The immunomodulatory abilities of TZD were evaluated by the

4 Mesenchymal stem cells (MSCs) possess unique immunomodulatory abilities.

5 One pathway with immunomodulatory ability is the tryptophan metabolism pa

6 on but also frees the host from the powerful immunomodulatory action of the parasites.

7 rse indirect effects induced by the multiple immunomodulatory actions of CMV.

8 erpinnings defining commensal gut microbiota immunomodulatory actions on physiologic bone remodeling

9 es for malignant glioma have to overcome the immunomodulatory activities of M2 monocytes that appear

10 ense peptides', emphasizing their additional immunomodulatory activities.

11 itumour, anti-inflammatory, antioxidant, and immunomodulatory activities.

12 ologically relevant context for their innate immunomodulatory activity in the dental pulp and their c

13 s are a class of small molecules with potent immunomodulatory activity linked to activation of Nrf2 t

14 er eradication of HCV with interferon, whose immunomodulatory activity might contribute to this effec

15 n to the antimicrobial activity of AMPs, the immunomodulatory activity of AMPs mediated by their inte

16 The immunomodulatory activity of cNK-2 involves the mitogen-

17 The results link the antiretroviral and immunomodulatory activity of Tetherin in vivo to improve

18 loratory end points included measures of the immunomodulatory activity of treatment by using IL-4 and

19 In addition, defensins have potent immunomodulatory activity that can alter innate and adap

20 -inflammatory response but retains effective immunomodulatory activity.

21 e potential functional food ingredients with immunomodulatory activity.

22 death, modulation of enzymatic activity, and immunomodulatory activity.

23 posures to BPA and EE can have estrogen-like immunomodulatory affects in both sexes.

24 Thus, IFN-lambda acted as a unique immunomodulatory agent by modifying transcriptional and

25 The efficacy of the anti-cancer immunomodulatory agent cyclophosphamide (CTX) relies on

26 g the Toll-like receptor (TLR) pathway using immunomodulatory agent GIT27.

27 Pegylated interferon alfa-2a is an immunomodulatory agent used to treat polycythemia vera.

28 Lenalidomide, an immunomodulatory agent, has shown activity in DLBCL.

29 yeloma (MM), including alkylators, steroids, immunomodulatory agents (IMiDs), proteasome inhibitors (

30 ients when CD38 antibodies are combined with immunomodulatory agents or proteasome inhibitors.

31 tic and antibiotic sparing roles for vaginal immunomodulatory agents that specifically target HDP ind

32 and second-generation proteasome inhibitors, immunomodulatory agents, and monoclonal antibodies.

33 internalization, making them effective TLR-9 immunomodulatory agents.

34 when combined with proteasome inhibitors and immunomodulatory agents.

35 antibacterial, antimalarial, anticancer, and immunomodulatory agents.

36 application of these compounds as potential immunomodulatory agents.

37 ted in combination therapy trials with other immunomodulatory agents.

38 have far-reaching benefits in enhancement of immunomodulatory and anti-cancer therapies.

39 erived protein hydrolysates or peptides with immunomodulatory and anticancer activities have been rep

40 The immunomodulatory and anticancer activities of food deriv

41 review provides a comprehensive overview of immunomodulatory and anticancer food derived protein hyd

42 Most immunomodulatory and anticancer food protein hydrolysate

43 monly employed process for the production of immunomodulatory and anticancer food protein hydrolysate

44 The fragment alphaS1-casein (1-23) is an immunomodulatory and antimicrobial peptide.

45 the spleens that reveal minor alterations in immunomodulatory and hematopoietic functions.

46 Whether the immunomodulatory and immunosuppressive medication agains

47 ACE) inhibitors, antioxidant, antimicrobial, immunomodulatory and opioidal peptides.

48 Phenols and phthalates may have immunomodulatory and proinflammatory effects and thereby

49 Such approaches can have immunomodulatory and thereby beneficial clinical effects

50 e complex properties of the cells, including immunomodulatory, anti-inflammatory, and proregenerative

51 These immunomodulatory antibodies offer the promise of durable

52 or immunology have led to the development of immunomodulatory antibodies targeting T cell coinhibitor

53 ng pathways, and how they may synergize with immunomodulatory antibodies that target PD1/PDL1 and CTL

54 t the beta-casein peptide (193-209) exhibits immunomodulatory, antimicrobial and antihypertensive act

55 T cell costimulation pathway is a promising immunomodulatory approach being developed to replace our

56 Here an immunomodulatory approach to stimulating nerve repair in

57 ys via activation of TLR7 represents a novel immunomodulatory approach to the treatment of allergic a

58 a single agent or in combination with other immunomodulatory approaches for glioblastoma.

59 hlighting the potential for developing novel immunomodulatory-based therapies to enable host-mediated

60 Some microbial metabolites can be immunomodulatory, but there is limited understanding of

61 Natural killer gene complex-encoded immunomodulatory C-type lectin-like receptors include me

62 The mechanisms underlying the altered immunomodulatory capacity of MSCs in the context of athe

63 etween clinical groups, correlate with HDL's immunomodulatory capacity, and may be predictive of HDL'

64 es was used as a prototypical assay of HDL's immunomodulatory capacity.

65 ut not the OSPW-OF caused both cytotoxic and immunomodulatory changes in mouse macrophages.

66 cacy, small risk for systemic reactions, and immunomodulatory changes in this single-season, dose-fin

67 The immunomodulatory character of pancreatic lysates of pati

68 tion with these defensive barrier functions, immunomodulatory cross-talk between the bronchial epithe

69 The potent immunomodulatory cytokine IL-6 is consistently up-regula

70 increase their production of the neuro- and immunomodulatory cytokine tumor necrosis factor (TNF).

71 IL-10 is an immunomodulatory cytokine with a critical role in limiti

72 e but is often primarily considered to be an immunomodulatory cytokine.

73 In addition, the levels of the immunomodulatory cytokines IL-1alpha and IL-10 were sign

74 Immunomodulatory derivatives (IMiDs), along with proteas

75 he CoMMpass study, all of which had received immunomodulatory drug (IMiD) therapy.

76 Lenalidomide is an immunomodulatory drug (IMiDs) with clinical efficacy in

77 including a proteasome inhibitor [PI] and an immunomodulatory drug [IMiD]) or were double refractory.

78 es in human P450-catalysed metabolism of the immunomodulatory drug leflunomide, which likewise underg

79 Our immunomodulatory drug regimen includes induction with an

80 vator and self-renewal agonist, and promotes immunomodulatory drug resistance in vitro.

81 Lenalidomide, an immunomodulatory drug with antineoplastic and antiprolif

82 revious regimens including bortezomib and an immunomodulatory drug, median overall survival was 25.5

83 o had received treatment with bortezomib, an immunomodulatory drug, or both, or who were receiving a

84 Pomalidomide, a third-generation immunomodulatory drug, was proposed to induce fetal hemo

85 The introduction of immunomodulatory drugs (IMiDs) and proteasome inhibitors

86 Immunomodulatory drugs (IMiDs) lenalidomide and pomalido

87 ide teratogenicity and antitumor activity of immunomodulatory drugs (IMiDs).

88 ssociation of LIS with the use of novel oral immunomodulatory drugs (IMiDs; lenalidomide and thalidom

89 Immunomodulatory drugs are active agents in light-chain

90 sing because of the HIV pandemic and because immunomodulatory drugs are increasingly used to treat au

91 ese results warrant further investigation of immunomodulatory drugs as maintenance in high-risk patie

92 Evidence suggests that immunomodulatory drugs can directly act on glomerular ep

93 tion of large phase III trials investigating immunomodulatory drugs for atherosclerosis, cardiovascul

94 the teratogenic and antitumor activities of immunomodulatory drugs such as thalidomide, lenalidomide

95 to the most recent proteasome inhibitors and immunomodulatory drugs used, and 103 (97%) were refracto

96 therapy (including proteasome inhibitors and immunomodulatory drugs), or were refractory to both prot

97 ents, purine analogs, proteasome inhibitors, immunomodulatory drugs, and mammalian target of rapamyci

98 t regimens containing proteasome inhibitors, immunomodulatory drugs, and monoclonal antibodies.

99 cluding new antiviral agents, symptomatic or immunomodulatory drugs, the re-emergence of natural reme

100 refractory to both proteasome inhibitors and immunomodulatory drugs, were randomly allocated in a 1:1

101 ous treatment with proteasome inhibitors and immunomodulatory drugs.

102 or GSPT1] whose ubiquitylation is induced by immunomodulatory drugs.

103 exposed to bortezomib, alkylators, and other immunomodulatory drugs.

104 NPM1 mutation and predicted the response to immunomodulatory drugs.

105 cial effects were associated with a systemic immunomodulatory effect associated with an increased CD4

106 aim of the present study is to determine the immunomodulatory effect of oral administration of vitami

107 trate that TsSPs have a potent and sustained immunomodulatory effect on human macrophage differentiat

108 ifaciens population, indirectly exerting its immunomodulatory effect on the intestine.

109 IV-1 mRNA, we demonstrated that despite this immunomodulatory effect, rapamycin did not affect HIV-1

110 IG) preparations have the potential to exert immunomodulatory effects as well as providing passive im

111 Ibrutinib has been shown to have immunomodulatory effects by inhibiting Bruton's tyrosine

112 r mechanisms, direct apoptotic activity, and immunomodulatory effects by the elimination of CD38(+) i

113 ngs can provide a variety of therapeutic and immunomodulatory effects for the treatment of acute lung

114 asites have been reported to have beneficial immunomodulatory effects in patients with allergic and a

115 accinia virus (VACV) K1 protein has multiple immunomodulatory effects in tissue culture models of inf

116 e properties including anti-inflammatory and immunomodulatory effects in various disease models and c

117 rahydrocannabinol (THC) have well documented immunomodulatory effects in vitro, but not following ora

118 ition of histone deacetylase 1 prevented the immunomodulatory effects of 2-aminoacetophenone.

119 from those patients were used to assess the immunomodulatory effects of cannabinoids.

120 host immune responses in the absence of the immunomodulatory effects of CD4(+) T cell targeting and

121 ion and repair, the authors investigated the immunomodulatory effects of DPSCs/I-DPSCs on macrophage

122 The significance of the immunomodulatory effects of IL-6 in the clinical setting

123 1 is the host receptor mediating the diverse immunomodulatory effects of mycolactone and identify Sec

124 hydrocarbon receptor signaling pathway, the immunomodulatory effects of nanomaterials, and the impac

125 Herein, we broadly identify the immunomodulatory effects of phylogenetically diverse hum

126 Taken together, the immunomodulatory effects of progestins differentially re

127 We then we review the immunomodulatory effects of statins and how they may att

128 Because immunomodulatory effects of type I interferon may be a f

129 The diverse immunomodulatory effects of vitamin D are increasingly b

130 ll contraction independent of its protective immunomodulatory effects on allergic airway inflammation

131 (UCA), a filaggrin breakdown product, exerts immunomodulatory effects on dendritic cells.

132 These immunomodulatory effects result from an array of molecul

133 Statins have wide-reaching immunomodulatory effects, and their use in the HIV-infec

134 rdiomyopathy, itMSC therapy was safe, caused immunomodulatory effects, and was associated with improv

135 rticoids on the podocyte, independent of the immunomodulatory effects, may lead to the identification

136 The data demonstrated MSC-induced immunomodulatory effects, the magnitude of which correla

137 ational anesthetics are bronchodilators with immunomodulatory effects.

138 lementary, and redundant transcriptional and immunomodulatory effects.

139 pneumonia (CAP) due to antiinflammatory and immunomodulatory effects.

140 gically important because it is required for immunomodulatory effects.

141 where they exert crucial anti-infectious and immunomodulatory effects.

142 Thus, it is important to identify immunomodulatory factors influencing Treg stability.

143 underscoring the multifaceted functions that immunomodulatory factors may acquire in an unpredictable

144 the blood environment and expresses various immunomodulatory factors necessary for survival and immu

145 ia infection causes keratinocytes to produce immunomodulatory factors that influence the outcome of i

146 ipocalins are multifaceted: they may have an immunomodulatory function and, furthermore, they represe

147 d tumors, which is largely attributed to the immunomodulatory function of this cytokine in tumor nich

148 lating hIL-10, cmvIL-10 could exert a direct immunomodulatory function, as demonstrated by its capaci

149 r HDL glycoprotein composition affects HDL's immunomodulatory function.

150 Vitamin D exerts multiple immunomodulatory functions and has been implicated in th

151 This work provides new insights into the immunomodulatory functions of ICP34.5.

152 Altogether, both the phagocytic and immunomodulatory functions of Mer regulate GC responses

153 hydrophobicity have the potential to extend immunomodulatory functions of serpins.

154 Our data indicate that RNase 7 has immunomodulatory functions on TH2 cells and decreases th

155 This viral homolog exhibits a range of immunomodulatory functions, including suppression of pro

156 netic manipulation of MSCs can enhance their immunomodulatory functions, which could be translated in

157 types and have been associated with multiple immunomodulatory functions.

158 l and their ability to mediate cytotoxic and immunomodulatory functions.

159 homeostasis, and its more recently revealed immunomodulatory functions.

160 GRP) is a neuropeptide with well-established immunomodulatory functions.

161 sferred CD8(+) T cells, we engineered CD200R immunomodulatory fusion proteins (IFPs) with the cytopla

162 Here, we present a proof-of-concept immunomodulatory gene circuit platform that enables tumo

163 However, only a small number of MCV immunomodulatory genes have been characterized in detail

164 ng and aged mice through the upregulation of immunomodulatory genes in secondary lymphoid tissues.

165 , thus enhancing injury as well as producing immunomodulatory IL-10.

166 refractory to both proteasome inhibitors and immunomodulatory imide drugs, time from diagnosis to ASC

167 ts a mechanism by which HCMV may amplify its immunomodulatory impact during infection.

168 icrobiota's ability to generate a consistent immunomodulatory impact, serving as a highly important e

169 m than oxLDL alone and that these ICs may be immunomodulatory in chronic disease and not just biomark

170 signaling and communication proteins such as immunomodulatory interleukin 6 as well as antioxidative

171 ia contribute to gut homeostasis through the immunomodulatory interleukin IL10, but there is little k

172 omarker analysis before and after adjunctive immunomodulatory intervention with high dose pulse corti

173 This study suggests that immunomodulatory interventions aimed at controlling cyto

174 Immunomodulatory interventions play a key role in the tr

175 s a model system to survey the extracellular immunomodulatory landscape.

176 Eosinophils are immunomodulatory leucocytes that contribute to the patho

177 and P3Cys-SVLPs) compared with SVLPs lacking immunomodulatory lipopeptides.

178 trates the therapeutic advantage of using an immunomodulatory mAb to regulate lymphoid cells, which t

179 ng mAb, anti-CD20, with an extended panel of immunomodulatory mAbs.

180 ecifically tag up to three prominent surface immunomodulatory macromolecules-peptidoglycan, lipopolys

181 Our results identify immune cells and immunomodulatory markers that can be potentially targete

182 While this type of immunomodulatory mechanism has already been demonstrated

183 NP application time studies suggest that the immunomodulatory mechanism is not due solely to the bloc

184 We investigated immunomodulatory mechanisms associated with clearance ve

185 s of AIT administration may induce different immunomodulatory mechanisms at the cellular level.

186 The elucidation of these clock-controlled immunomodulatory mechanisms might uncover new approaches

187 a suggest that OECs have neuroprotective and immunomodulatory mechanisms that create a supportive env

188 al a new addition to the repertoire of ES-62 immunomodulatory mechanisms with possible therapeutic ap

189 eveals that a consequence of exposure to the immunomodulatory metabolite itaconate is B12 inactivatio

190 nking its function to B12 metabolism and the immunomodulatory metabolite, itaconate.

191 CLL-EVs containing miR-363 that targets the immunomodulatory molecule CD69.

192 of rheumatoid arthritis demonstrate that the immunomodulatory molecule IDO2 modifies responses to sel

193 ine the poorly studied Rho GTPase TC10 as an immunomodulatory molecule playing a role in physiologica

194 mes (Ecto) from their surface, which express immunomodulatory molecules like phosphatidylserine or TG

195 uman commensal Bacteroides fragilis delivers immunomodulatory molecules to immune cells via secretion

196 rophylactic treatment with H. pylori-derived immunomodulatory molecules, affects the onset and severi

197 Immunomodulatory monoclonal Abs have also been successfu

198 those with antihypertensive, antimicrobial, immunomodulatory, opioid and anti-oxidative functions.

199 phenolate mofetil improvers, suggesting that immunomodulatory or combination therapy may have benefit

200 -based AND gate that generates combinatorial immunomodulatory outputs only when both promoters are mu

201 Activation of immunomodulatory pathways in response to invasive fungi

202 Helminths trigger multiple immunomodulatory pathways that can protect from sepsis.

203 the late phase of cardioprotection, antigen immunomodulatory pathways were activated with upregulati

204 kocytes to induce the activation of distinct immunomodulatory pathways.

205 ide sequence, we rationally designed a novel immunomodulatory peptide that targets TCR.

206 e of DNA methylation within AC confers their immunomodulatory plasticity.

207 of cryopreservation on human MSC viability, immunomodulatory potency, growth factor secretion, and p

208 ted by cell-to-cell contact, attenuating its immunomodulatory potency.

209 es of the AMPs against human cells and their immunomodulatory potential in human blood were also char

210 Collectively, these results highlight the immunomodulatory potential of antibiotics and reveal the

211 Here, we examined the immunomodulatory potential of flavones, a class of flavo

212 recognition by the host while retaining the immunomodulatory potential of their saliva.

213 l of proinflammatory, anti-inflammatory, and immunomodulatory processes.

214 ived MSCs and examined their immunogenic and immunomodulatory properties before and after stimulation

215 ide, which exhibits potent antimicrobial and immunomodulatory properties both in vitro and in vivo.

216 nonviral DNA/gene delivery approach endowing immunomodulatory properties for DNA vaccines.

217 Given the immunomodulatory properties of efferocytosis, understand

218 oad and potent immune responses based on the immunomodulatory properties of Fc-FcgammaR interactions.

219 of mitochondrial dysfunction in the impaired immunomodulatory properties of MSCs from patients with a

220 As such, human studies on the immunomodulatory properties of norepinephrine and viable

221 While the immunomodulatory properties of progestins protected immu

222 We compared the immunomodulatory properties of strain A2-165 to four dif

223 traception provides strong impetus to define immunomodulatory properties of this exogenous progestin.

224 cargo, ragweed pollen shells have additional immunomodulatory properties that help the orally deliver

225 f Western blotting, and the final outcome on immunomodulatory properties was evaluated based on real-

226 CMV-specific immunity but also exert complex immunomodulatory properties which augment the antiviral

227 SMCs also regulate several immunomodulatory properties within immune cells.

228 neously, synthesized nanostructures maintain immunomodulatory properties, described previously for fr

229 tural killer T (iNKT) cells, with remarkable immunomodulatory properties, participate in TSS is uncle

230 DHA, an essential fatty acid with immunomodulatory properties, was tested because its plas

231 e immune cell population endowed with potent immunomodulatory properties.

232 e between StII pore-forming activity and its immunomodulatory properties.

233 host defense peptide with antimicrobial and immunomodulatory properties.

234 olecules has also increased because of their immunomodulatory properties.

235 ontact, followed by the determination of its immunomodulatory properties.

236 direct-acting antivirals (DAAs), which lack immunomodulatory properties.

237 PGE2, a major immunomodulatory prostanoid, acts as a proinflammatory a

238 Specifically, the Ad-encoded E3-19K immunomodulatory protein targets MHC class I molecules f

239 hogen Streptococcus pyogenes secretes potent immunomodulatory proteins known as superantigens (SAgs),

240 polymorphism (SNP) of the gene encoding the immunomodulatory receptor CTLA-4 that was associated wit

241 The immunomodulatory receptor Siglec-3/CD33 influences risk

242 r expressed on myeloid cells-2 (TREM2) is an immunomodulatory receptor with a central role in myeloid

243 ffectors such as myeloid cells, or targeting immunomodulatory receptors to promote cytotoxic T cell r

244 tion of IL-2 and CNIs constitutes an optimal immunomodulatory regimen that enhances the pool of suppr

245 This study demonstrates the differential immunomodulatory responses of blood monocytes, particula

246 ubiquitin-like protein, is known to have an immunomodulatory role and can have a direct antiviral ef

247 study suggest that ISG15 plays an important immunomodulatory role and regulates HEV sensitivity to e

248 ion in Huh7-S10-3 human liver cells plays an immunomodulatory role by negatively regulating type I IF

249 the epithelium and granulopoiesis, this new immunomodulatory role could explain the protection confe

250 We establish a novel immunomodulatory role for Dkk1 in regulating tumor-induc

251 minotransferase and, importantly, reveals an immunomodulatory role for indolepyruvate.

252 he antiviral effect as well as the potential immunomodulatory role of ISG15 during HEV replication.

253 Therefore, our results identify the novel immunomodulatory role of MYC in human pDC and may add to

254 anulation specifically without affecting the immunomodulatory role of these cells.

255 ctivates NF-kappaB-, AP-1-, and STAT3-driven immunomodulatory signaling pathways specifically within

256 e and that circulating exosomes transporting immunomodulatory signals, may play a role fundamental ro

257 On-site delivery of the immunomodulatory small molecule FTY720 recruits S1PR3-ex

258 c treatment resistance, suggesting potential immunomodulatory strategies to enhance the long-term cli

259 ely aid in the rational development of novel immunomodulatory strategies to prolong graft survival an

260 supports the further development of targeted immunomodulatory strategies to treat DENV disease.IMPORT

261 The immunomodulatory surface molecules of commensal and path

262 f the DosR regulon, a critical metabolic and immunomodulatory switch induced by NO, carbon monoxide,

263 we set out to further understand CD27 as an immunomodulatory target and to address the mechanism of

264 ing the mTOR signaling network an attractive immunomodulatory target for autoimmune-related diseases.

265 g amebic colitis, and highlights a potential immunomodulatory target.

266 nd providing insights into the potential for immunomodulatory therapeutic interventions.

267 a basic understanding of CD28 function into immunomodulatory therapeutics has been uneven, with both

268 n, including the perspectives of delivery of immunomodulatory therapeutics, engineering immune cells,

269 IL-1RI, thereby suggesting a novel route to immunomodulatory therapeutics.The cytokine interleukin 1

270 Although 12 immunomodulatory therapies exist, they have only modest

271 Immunomodulatory therapies should be investigated in adu

272 micro- and nanoparticles are often added to immunomodulatory therapies to enhance the triggered immu

273 gether, our data highlight the potential for immunomodulatory therapies to stimulate alveologenesis i

274 Emerging evidence suggests that immunomodulatory therapies used in nephrotic syndrome di

275 detrimental or beneficial, before developing immunomodulatory therapies, it is necessary to better un

276 creates new translational possibilities for immunomodulatory therapies, specifically vaginal therapi

277 ssues to better inform future application of immunomodulatory therapies.

278 documenting immune responses in studies for immunomodulatory therapies.

279 sence of major comorbidities, treatment with immunomodulatory therapy and disruption of the microbiom

280 onparaneoplastic AIR patients with long-term immunomodulatory therapy and that there is enough equipo

281 heson 2014 criteria and LYmphoma Response to Immunomodulatory therapy Criteria (LYRIC) (2016 revised

282 The issue of attempting immunomodulatory therapy is discussed in view of the pub

283 y IL-1 response could be used as a potential immunomodulatory therapy to improve the outcome of asper

284 ddress this issue in the context of lymphoma immunomodulatory therapy, a workshop was convened to pro

285 c immunoglobulins are used as replacement or immunomodulatory therapy, but can transmit clinically im

286 tivitis other than MMP, rather than systemic immunomodulatory therapy, resulting in irreversible clin

287 bidity despite continuous systemic and local immunomodulatory therapy.

288 IVIg is widely used as an immunomodulatory therapy.

289 combination of systemic corticosteroids and immunomodulatory therapy.

290 ng inflamed eyes being treated with systemic immunomodulatory therapy.

291 seizure frequency was associated with use of immunomodulatory therapy.

292 g as well as for development of prophylactic immunomodulatory therapy.

293 plastic AIR should be treated with long-term immunomodulatory therapy.

294 IR patients should be treated with long-term immunomodulatory therapy.

295 nic demyelinating optic neuropathy on stable immunomodulatory therapy.

296 not in plasma, were substantially above the immunomodulatory threshold in murine and human lymphocyt

297 axis blockade using IDEC-131 is an inferior immunomodulatory treatment than 5C8H1 or 2C10R4, which h

298 CD20-expressing T cells respond variably to immunomodulatory treatments given to MS patients: they a

299 of food allergy and the clinical response to immunomodulatory treatments.

300 er-invasive forms by enhancing expression of immunomodulatory virulence factors, and examples that pr