ライフサイエンスコーパス: immunoreceptor

1 eracts with both the effector and the NB-LRR immunoreceptor.

2 ase involved in cell signaling downstream of immunoreceptors.

3 to these aspartic acids, with the activating immunoreceptors.

4 he molecular organization of many activating immunoreceptors.

5 mits signals upon ligation of many different immunoreceptors.

6 ed by cytokines dependent on TLR and/or MDA5 immunoreceptors.

7 alpha (SIRPalpha) is a membrane glycoprotein immunoreceptor abundant in cells of monocyte lineage.

8 uch as antisense oligonucleotides, aptamers, immunoreceptor-activating nucleotides, or (anti)microRNA

9 ory role for Btk and Tec that is mediated by immunoreceptor activation and signaling via PI3K.

10 ally encoded Ca(2+) signaling in response to immunoreceptor activation that utilizes TRPC channels to

11 mmobility is a feature of highly crosslinked immunoreceptor aggregates and a trigger for receptor int

12 (SLP-76) is an adaptor molecule critical for immunoreceptor and integrin signaling in multiple hemopo

13 rements for the domains of Syk and SLP-76 in immunoreceptor and integrin signaling.

14 uggesting functional similarity between this immunoreceptor and tumor growth factor receptors.

15 ine-based activation motif (ITAM)-containing immunoreceptors and integrins.

16 plex class I (MHCI) family, and MHCI-binding immunoreceptors and their components (e.g., PIRB, Ly49,

17 d for their activities downstream of several immunoreceptors and then functionally mapped based on th

18 ing lymphocyte activating molecule family of immunoreceptors, and has an unknown function in CLL cell

19 state organisation and diffusion dynamics of immunoreceptors, and how this might impact on our unders

20 Like LAIR-1, CD33 inhibitory immunoreceptors are highly expressed on monocytes.

21 g the two clones with identical TCR Vbeta by immunoreceptor array showed higher phosphorylation of NK

22 Many activating immunoreceptors associate with signaling adaptor molecul

23 The immunoreceptor-associated protein CD3zeta is known for i

24 d recruitment of this adaptor protein to the immunoreceptor-based activation motif (ITAM)-like sequen

25 bitors, thus indicating the activation of an immunoreceptor-based tyrosine activation motif-mediated

26 s to pDCs via the C-type lectins DEC-205, DC immunoreceptor, blood DC Ag-2, or the FcR CD32 led to up

27 us vulgaris (PV), autoantigen-based chimeric immunoreceptors can direct T cells to kill autoreactive

28 signaling pathways that are activated by an immunoreceptor (CD86) and a neuroreceptor (beta2AR) conv

29 in E2 is a novel ligand of pDC C-type lectin immunoreceptors (CLRs), blood DC antigen 2 (BDCA-2) and

30 L in human CAECs and indicate that these two immunoreceptors contribute to the mechanisms underlying

31 Upon activation by immunoreceptors, CPR5 undergoes an oligomer to monomer c

32 Dendritic cell immunoreceptor (DCIR) constructs in CHO cells or on DCs

33 estigated the role of the CLR dendritic cell immunoreceptor (DCIR) in the genesis of CM.

34 proteins, and given that the dendritic cell immunoreceptor (DCIR) is known to act as a negative regu

35 yrosine-based inhibitory motif-containing DC immunoreceptor (DCIR) to mediate potent cross-presentati

36 eport that C-type lectin dendritic cell (DC) immunoreceptor (DCIR), a key component in DC homeostasis

37 s (CLRs), blood DC antigen 2 (BDCA-2) and DC-immunoreceptor (DCIR).

38 KC isoforms and CARMA1 play crucial roles in immunoreceptor-dependent NF-kappaB activation.

39 nd the kinase domain of Syk are required for immunoreceptor-dependent signaling and cellular response

40 Critical cell surface immunoreceptors downregulated during HIV infection have

41 These data support the notion that immunoreceptor downregulation occurs by a sequential pro

42 Interaction with host immunoreceptors during microbial infection directly impa

43 d calcium entry (SOCE), occurs downstream of immunoreceptor engagement and is critical for cytotoxic

44 reorganization, and gene transcription upon immunoreceptor engagement.

45 able interest in the signaling mechanisms of immunoreceptors, especially when triggered with membrane

46 r expressed on myeloid cells-1) is an orphan immunoreceptor expressed on monocytes, macrophages, and

47 TREM2 is an immunoreceptor expressed on osteoclasts (OC) and microgl

48 esults suggest that tumor co-option of NKG2D immunoreceptor expression may complement the presence of

49 with homologous lectin-like domains from the immunoreceptor family reveals a similar but not identica

50 Activation of the plant immunoreceptor Flagellin sensing2 (FLS2) by its bacteria

51 re NLRs that appear to function as cytosolic immunoreceptors for specific bacterial proteins, includi

52 le nucleotide polymorphism (rs231725) of the immunoreceptor gene cytotoxic T-lymphocyte antigen 4 (CT

53 ur data suggest that after the engagement of immunoreceptors, immune cells likely employ multiple mem

54 of the T cell receptor-CD3 complex and other immunoreceptors in immune synapses.

55 ase Syk is required for signaling of several immunoreceptors, including the BCR and FcR.

56 oprotein of 76 kDa) organizes signaling from immunoreceptors, including the platelet collagen recepto

57 Signaling by immunoreceptors is often initiated by phosphorylation of

58 B7-H6, a member of the B7 family of immunoreceptors, is as a cell-surface ligand for the NKp

59 n motifs in the cytoplasmic tail of multiple immunoreceptors, leading to the initiation of cellular e

60 in-like-5/CD155) in complex with its cognate immunoreceptor ligand T-cell-Ig-and-ITIM-domain (TIGIT).

61 d for producing multiple functionally active immunoreceptors, ligands, and viral decoys, including ch

62 promote phosphorylation events necessary for immunoreceptor-mediated inhibition of TLR signaling.

63 ther showed that, in contrast to its role in immunoreceptor-mediated signaling, LAB function in LPS-m

64 nsmembrane adaptor protein that functions in immunoreceptor-mediated signaling.

65 Movement of immunoreceptor microclusters tunes lymphocyte activation

66 These include adhesive receptors, immunoreceptors, motor proteins, cytoskeletal proteins,

67 ewise, serves as a ligand for the activating immunoreceptor natural killer group 2, D (NKG2D), also e

68 In contrast, the ligands of the activating immunoreceptor NKG2D (NKG2DL) are selectively expressed

69 express ligands for the natural killer cell immunoreceptor NKG2D, which sensitizes to early recognit

70 The immunoreceptors NKG2D and NKp46 are known for their capa

71 tion from disorder to order upon binding its immunoreceptor, NKG2D.

72 a secretome library, we found that the human immunoreceptor NKp44, encoded by NCR2 and expressed on n

73 h as tartrate-resistant acid phosphatase and immunoreceptor OCL-associated receptor, which are known

74 leotide binding leucine-rich repeat (NB-LRR) immunoreceptors recognize specific pathogen effectors di

75 gulation in which engagement of a macrophage immunoreceptor recruits a stimulatory G protein-coupled

76 ngaging and activating the LAIR-1 inhibitory immunoreceptor represents a non-complement mechanism for

77 ractions are strikingly similar to mammalian immunoreceptor-SFK-Syk signalling events in mammalian my

78 nstrate an important role for TM segments in immunoreceptor signaling and a strong correspondence bet

79 hich then enlists selected components of the immunoreceptor signaling cascade to transmit amplificati

80 The role of PAG as a negative regulator of immunoreceptor signaling has been examined in several mo

81 yrosine kinase, is an important component of immunoreceptor signaling in hematopoietic cells.

82 natural allelic variation in 5 genes of the immunoreceptor signaling pathway (IgH, Dok3, Src, Syk, a

83 vely regulating Src family kinases (SFKs) in immunoreceptor signaling pathways in B cells and macroph

84 rosine kinase (SYK) has an important role in immunoreceptor signaling, and SYK inhibition has accordi

85 Gads-binding domain of SLP-76 is needed for immunoreceptor signaling, it appears dispensable for int

86 vious data have reported that SLAP regulates immunoreceptor signaling.

87 nd myeloid lineage development and defective immunoreceptor signaling.

88 anisms may be an important factor modulating immunoreceptor signaling.

89 sequently, our results suggest that adaptive immunoreceptor-signaling pathways important in distingui

90 rovide insight into the interactions between immunoreceptor signals in a human cancer microenvironmen

91 n that interacts with the myeloid inhibitory immunoreceptor SIRPalpha (also termed CD172a or SHPS-1).

92 osis through interaction with the inhibitory immunoreceptor SIRPalpha expressed by macrophages.

93 its counter-receptor, the myeloid inhibitory immunoreceptor SIRPalpha.

94 tions in signaling initiated from activating immunoreceptors such as B cell Ag receptor.

95 After the engagement of immunoreceptors such as T-cell and B-cell antigen recept

96 to tyrosine-phosphorylated ITAM subunits of immunoreceptors, such as FcepsilonRI on mast cells, resu

97 Thus, CEACAM2 is a novel platelet immunoreceptor that acts as a negative regulator of plat

98 NKG2D is a potent activating immunoreceptor that has emerged as an important player i

99 yte antigen 4 (CTLA4) encodes a coinhibitory immunoreceptor that is a key regulator of self-tolerance

100 Identification of the immunoreceptors that bind SP-D is essential for understa

101 (PDCD1) are two genes encoding coinhibitory immunoreceptors that harbor polymorphisms with demonstra

102 ignaling: signals initiated by engagement of immunoreceptors that lead to conformational changes and

103 engagement of G-protein-coupled receptors or immunoreceptors, the extracellular domains of L-selectin

104 des descending from integrins are similar to immunoreceptors, the mechanism of Syk activation and SLP

105 urrently associates with distinct inhibitory immunoreceptors to produce C1q-mediated modulatory netwo

106 nt solution NMR structure of the DAP12-NKG2C immunoreceptor transmembrane helix complex, five functio

107 Here we report that platelet immunoreceptor tyrosine activation motif (ITAM) signalin

108 Many of them are immunoreceptor tyrosine inhibitory motif (ITIM)-containi

109 at DNAM-1 promotes NK cell activation via an immunoreceptor tyrosine tail (ITT)-like motif coupling D

110 Notably, the open conformation required immunoreceptor tyrosine-activation motif and continuous

111 To test the role of Src family kinases and immunoreceptor tyrosine-based activating motif (ITAM)-co

112 ransfected cells required the presence of an immunoreceptor tyrosine-based activating motif-bearing a

113 ins interacting with a doubly phosphorylated immunoreceptor tyrosine-based activation motif (dp-ITAM)

114 ic sequence motif of NKp65 resembling a hemi-immunoreceptor tyrosine-based activation motif (hemITAM)

115 single cytoplasmic YxxL motif known as a hem immunoreceptor tyrosine-based activation motif (hemITAM)

116 it is the only one to signal through a hemi-immunoreceptor tyrosine-based activation motif (hemITAM)

117 2 mediates platelet activation through a hem-immunoreceptor tyrosine-based activation motif (hemITAM)

118 induced IL-4 production was dependent on the immunoreceptor tyrosine-based activation motif (ITAM) ad

119 osphorylated DAP12, an adaptor containing an immunoreceptor tyrosine-based activation motif (ITAM) an

120 release in response to stimulation of (hem) immunoreceptor tyrosine-based activation motif (ITAM) an

121 Through its immunoreceptor tyrosine-based activation motif (ITAM) an

122 ansmembrane glycoprotein having a functional immunoreceptor tyrosine-based activation motif (ITAM) ca

123 in kinase C, all downstream mediators of the immunoreceptor tyrosine-based activation motif (ITAM) ca

124 ough activating Fcgamma receptors bearing an immunoreceptor tyrosine-based activation motif (ITAM) in

125 lian Syk and Zap-70, binds Draper through an immunoreceptor tyrosine-based activation motif (ITAM) in

126 A signaling immunoreceptor tyrosine-based activation motif (ITAM) in

127 kinase activity and consequent to biased BCR immunoreceptor tyrosine-based activation motif (ITAM) mo

128 et glycoprotein receptors that signal via an immunoreceptor tyrosine-based activation motif (ITAM) or

129 he B cell antigen receptor (BCR) via the non-immunoreceptor tyrosine-based activation motif (ITAM) ph

130 duces receptor oligomerization, Igalpha/beta immunoreceptor tyrosine-based activation motif (ITAM) ph

131 Previously, we had shown that activation of immunoreceptor tyrosine-based activation motif (ITAM) pr

132 y to associate with c-Src is mediated by the immunoreceptor tyrosine-based activation motif (ITAM) pr

133 tion, and that this phenotype depended on an immunoreceptor tyrosine-based activation motif (ITAM) pr

134 rment of differentiation required the PY and immunoreceptor tyrosine-based activation motif (ITAM) si

135 ine kinase family plays an essential role in immunoreceptor tyrosine-based activation motif (ITAM) si

136 Somatic mutations affecting the immunoreceptor tyrosine-based activation motif (ITAM) si

137 DAP12 is a signaling adaptor containing an immunoreceptor tyrosine-based activation motif (ITAM) th

138 osphorylated on two tyrosine residues of the immunoreceptor tyrosine-based activation motif (ITAM), l

139 d by 2 receptors that signal through an (hem)immunoreceptor tyrosine-based activation motif (ITAM), t

140 ng pathway that relies on a highly conserved immunoreceptor tyrosine-based activation motif (ITAM), w

141 Unexpectedly, however, immunoreceptor tyrosine-based activation motif (ITAM)- a

142 rs have been shown to inhibit signaling from immunoreceptor tyrosine-based activation motif (ITAM)-co

143 An important function of immunoreceptor tyrosine-based activation motif (ITAM)-co

144 that a signaling pathway mediated by the DC immunoreceptor tyrosine-based activation motif (ITAM)-co

145 target cell interactions or ligation of the immunoreceptor tyrosine-based activation motif (ITAM)-co

146 NK cell-activating receptors signal through immunoreceptor tyrosine-based activation motif (ITAM)-co

147 Immunoreceptor tyrosine-based activation motif (ITAM)-co

148 te that a signaling pathway initiated by the immunoreceptor tyrosine-based activation motif (ITAM)-co

149 Immunoreceptor tyrosine-based activation motif (ITAM)-co

150 signaling mediators activated downstream of immunoreceptor tyrosine-based activation motif (ITAM)-co

151 Expression of immunoreceptor tyrosine-based activation motif (ITAM)-co

152 In contrast, deficiency in the immunoreceptor tyrosine-based activation motif (ITAM)-co

153 er, little is known about how CD45 regulates immunoreceptor tyrosine-based activation motif (ITAM)-de

154 mmatory disease, which signal through a (hem)immunoreceptor tyrosine-based activation motif (ITAM)-de

155 receptors inhibit cellular responsiveness to immunoreceptor tyrosine-based activation motif (ITAM)-li

156 ike protein 5 (FCRL5) on B cells has both an immunoreceptor tyrosine-based activation motif (ITAM)-li

157 show that although CD45 is necessary for all immunoreceptor tyrosine-based activation motif (ITAM)-sp

158 nd the Fc receptor gamma-chain, which has an immunoreceptor tyrosine-based activation motif (ITAM).

159 motes engulfment of axonal debris through an immunoreceptor tyrosine-based activation motif (ITAM).

160 izes two tandem YXXL repeats presented as an immunoreceptor tyrosine-based activation motif (ITAM).

161 gnaling, including CD79a, a protein with the immunoreceptor tyrosine-based activation motif (ITAM).

162 nsmembrane glycoprotein bearing a functional immunoreceptor tyrosine-based activation motif (ITAM).

163 d a previously unrecognized carboxy-terminal immunoreceptor tyrosine-based activation motif (ITAM).

164 tyrosine residues arranged in a noncanonical immunoreceptor tyrosine-based activation motif (ITAM).

165 C: central supramolecular activation cluster Immunoreceptor tyrosine-based activation motif (ITAM): a

166 express K1 and a K1 mutant with the deleted immunoreceptor tyrosine-based activation motif (K1m).

167 With the use of a phosphorylated immunoreceptor tyrosine-based activation motif (pITAM) p

168 intracytoplasmic tails (FcgammaRIIa with an immunoreceptor tyrosine-based activation motif [ITAM] an

169 However, DAP10 has no immunoreceptor tyrosine-based activation motif and thus

170 ytokine receptor-mediated responses, whereas immunoreceptor tyrosine-based activation motif containin

171 While it contains an immunoreceptor tyrosine-based activation motif in its cy

172 have also determined that an intact FcgammaR immunoreceptor tyrosine-based activation motif is requir

173 Conversely, Y188F mutation in the immunoreceptor tyrosine-based activation motif of CD79A

174 III, and IV induces cell activation via the immunoreceptor tyrosine-based activation motif on the co

175 showed that both tyrosines of the CD3epsilon immunoreceptor tyrosine-based activation motif partition

176 itogen-activated protein kinase pathway, the immunoreceptor tyrosine-based activation motif pathway,

177 receptors in hemostasis, the contribution of immunoreceptor tyrosine-based activation motif receptors

178 3 glycoproteins that belong to the family of immunoreceptor tyrosine-based activation motif receptors

179 that CLP36 acts as a major inhibitor of GPVI immunoreceptor tyrosine-based activation motif signaling

180 veal an inhibitory function of CLP36 in GPVI immunoreceptor tyrosine-based activation motif signaling

181 to summarize recent findings on how platelet immunoreceptor tyrosine-based activation motif signaling

182 ever, have identified new roles for platelet immunoreceptor tyrosine-based activation motif signaling

183 al an important contribution of Grb2 in (hem)immunoreceptor tyrosine-based activation motif signaling

184 at Grb2 is a crucial adapter protein in (hem)immunoreceptor tyrosine-based activation motif signaling

185 In vivo, this selective (hem)immunoreceptor tyrosine-based activation motif signaling

186 (BCR), and its cytoplasmic tail contains an immunoreceptor tyrosine-based activation motif that can

187 Phosphorylation of the conserved immunoreceptor tyrosine-based activation motif tyrosines

188 Mechanistically, the LMP2A immunoreceptor tyrosine-based activation motif was criti

189 d cytoplasmic domain, inclusive of the ITAM (immunoreceptor tyrosine-based activation motif) involved

190 acids in a sequence known as a hemITAM (hemi-immunoreceptor tyrosine-based activation motif).

191 y receptors that have 1 or more copies of an immunoreceptor tyrosine-based activation motif, defined

192 nsduced phosphorylation of its intracellular immunoreceptor tyrosine-based activation motif, which in

193 all-trans-retinoic acid treatment or active immunoreceptor tyrosine-based activation motif-bearing (

194 in receptors, such as Ly49H, associated with immunoreceptor tyrosine-based activation motif-bearing a

195 The hemi-immunoreceptor tyrosine-based activation motif-containin

196 naling as well as costimulatory signals from immunoreceptor tyrosine-based activation motif-containin

197 s, including the integrin alphaIIbbeta3, the immunoreceptor tyrosine-based activation motif-containin

198 prevent inflammatory bleeding through (hem) immunoreceptor tyrosine-based activation motif-dependent

199 latory signal that prevents expression of an immunoreceptor tyrosine-based activation motif-free IgE

200 (NFATc1, RANK, costimulatory receptors, and immunoreceptor tyrosine-based activation motif-harboring

201 lucan component of yeast is dependent on the immunoreceptor tyrosine-based activation motif-like doma

202 Lyn Src-family kinase with an intracellular immunoreceptor tyrosine-based activation motif-like sequ

203 ation of two tyrosine residues located in an immunoreceptor tyrosine-based activation motif-like sequ

204 e evident despite a severe impairment of the immunoreceptor tyrosine-based activation motif-mediated

205 ytotoxicity via an atypical cytoplasmic hemi-immunoreceptor tyrosine-based activation motif.

206 am of the Fc receptor gamma-chain-associated immunoreceptor tyrosine-based activation motif.

207 platelet activation that both signal via an immunoreceptor tyrosine-based activation motif.

208 tetherin cytoplasmic tail resembles the hemi-immunoreceptor tyrosine-based activation motifs (hemITAM

209 wn tyrosine phosphorylation sites within the immunoreceptor tyrosine-based activation motifs (ITAM) o

210 with each receptor independently through the immunoreceptor tyrosine-based activation motifs (ITAMs)

211 nt function of receptors that signal through immunoreceptor tyrosine-based activation motifs (ITAMs)

212 responses depends on the phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs)

213 Clustering of receptors associated with immunoreceptor tyrosine-based activation motifs (ITAMs)

214 Immunoreceptor tyrosine-based activation motifs (ITAMs)

215 Adaptor molecules bearing immunoreceptor tyrosine-based activation motifs (ITAMs)

216 icate balance between receptors that contain immunoreceptor tyrosine-based activation motifs (ITAMs)

217 ceptor signaling through adaptors containing immunoreceptor tyrosine-based activation motifs (ITAMs),

218 elopment can proceed with as few as 4/10 CD3 immunoreceptor tyrosine-based activation motifs (ITAMs),

219 ion to the tyrosines of the Igalpha and beta immunoreceptor tyrosine-based activation motifs (ITAMs),

220 orylated by the phosphatase CD45 on multiple immunoreceptor tyrosine-based activation motifs (ITAMs).

221 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs).

222 e regulated by receptors that signal through immunoreceptor tyrosine-based activation motifs (ITAMs).

223 a tandem SH2 unit responsible for binding to immunoreceptor tyrosine-based activation motifs (ITAMs).

224 R through interaction with RhoH noncanonical immunoreceptor tyrosine-based activation motifs (ITAMs).

225 0 sites that are distributed on 10 conserved immunoreceptor tyrosine-based activation motifs (ITAMs).

226 equirements for a large number of functional immunoreceptor tyrosine-based activation motifs (ITAMs;

227 ich associate with adaptor molecules bearing immunoreceptor tyrosine-based activation motifs and indu

228 nRI alpha-chains induces cell activation via immunoreceptor tyrosine-based activation motifs in assoc

229 Its zeta-subunit contains multiple cytosolic immunoreceptor tyrosine-based activation motifs involved

230 ly by two amino acid sequence motifs, ITAMs (immunoreceptor tyrosine-based activation motifs) and ITI

231 induces a multitude of positive signals via immunoreceptor tyrosine-based activation motifs, which l

232 sphorylated tyrosines within the FcepsilonRI immunoreceptor tyrosine-based activation motifs.

233 vation by other receptor complexes that lack immunoreceptor tyrosine-based activation motifs.

234 integrin Mac-1 and utilize signals involving immunoreceptor tyrosine-based activation motifs.

235 cyt apparently controls accessibility of the immunoreceptor tyrosine-based activation signal transduc

236 dues, but none of the Tyr residues match the immunoreceptor tyrosine-based activation, inhibitory, or

237 the cytoplasmic domains of gB (gBcyt) via an immunoreceptor tyrosine-based inhibition motif (ITIM) an

238 The present study identifies a canonical immunoreceptor tyrosine-based inhibition motif (ITIM) in

239 tor pair that recruited components to CD33's immunoreceptor tyrosine-based inhibition motif (ITIM), i

240 brane receptor-like protein that contains an immunoreceptor tyrosine-based inhibition motif (ITIM), w

241 Since their discovery, immunoreceptor tyrosine-based inhibition motif (ITIM)-co

242 ealed that these processes require the ITIM (immunoreceptor tyrosine-based inhibition motif) of the r

243 This immunoreceptor tyrosine-based inhibition motif-bearing r

244 Deletion of the immunoreceptor tyrosine-based inhibition motif-containin

245 egulation was dependent upon the presence of immunoreceptor tyrosine-based inhibition motifs (ITIM) w

246 are controlled by receptors with cytoplasmic immunoreceptor tyrosine-based inhibition motifs (ITIMs).

247 Both CD31 intracellular immunoreceptor tyrosine-based inhibition motifs are requ

248 In contrast, mice with mutated CD22 immunoreceptor tyrosine-based inhibition motifs have inc

249 Phosphorylation of immunoreceptor tyrosine-based inhibition motifs in its c

250 at least in part, because the phosphorylated immunoreceptor tyrosine-based inhibition motifs recruit

251 s), dampening immune responses via cytosolic immunoreceptor tyrosine-based inhibition motifs that rec

252 tyrosine-based activation motifs) and ITIMs (immunoreceptor tyrosine-based inhibition motifs) that ac

253 FcgammaRIIB mediates inhibitory signals via immunoreceptor tyrosine-based inhibition motifs.

254 b is an inhibitory platelet receptor with an immunoreceptor tyrosine-based inhibitory motif (ITIM) an

255 CD300a is an immunoreceptor tyrosine-based inhibitory motif (ITIM) co

256 ock-in mouse with a targeted mutation in the immunoreceptor tyrosine-based inhibitory motif (ITIM) of

257 RIIb on the surface of B cells, resulting in immunoreceptor tyrosine-based inhibitory motif (ITIM) ph

258 We show that vGPCR contains a bona fide immunoreceptor tyrosine-based inhibitory motif (ITIM) th

259 CD33 contains a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM), w

260 DCAL-2 is a CLR with a cytosolic immunoreceptor tyrosine-based inhibitory motif (ITIM), w

261 Immunoreceptor tyrosine-based inhibitory motif (ITIM)-co

262 I signaling through a previously undescribed immunoreceptor tyrosine-based inhibitory motif (ITIM)-li

263 ivation motif [ITAM] and FcgammaRIIb with an immunoreceptor tyrosine-based inhibitory motif [ITIM]).

264 ppressive receptor T-cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain (T

265 CRP-induced increases in FcgammaRIIB immunoreceptor tyrosine-based inhibitory motif phosphory

266 riable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif that was

267 ptor Fcgamma receptor IIB (FcgammaRIIB), its immunoreceptor tyrosine-based inhibitory motif, and SH2

268 We found the immunoreceptor tyrosine-based inhibitory motif-containin

269 hibit T cell responses via engagement of the immunoreceptor tyrosine-based inhibitory motif-containin

270 -transduced HEK293T cells required an intact immunoreceptor tyrosine-based inhibitory motif.

271 osine phosphatase 1 (SHP-1) to a cytoplasmic immunoreceptor tyrosine-based inhibitory motif.

272 motif (ITAM)-like sequence and two consensus immunoreceptor tyrosine-based inhibitory motifs (ITIM) i

273 lagen tail trigger phosphorylation of LAIR-1 immunoreceptor tyrosine-based inhibitory motifs (ITIMs)

274 ivity to LM infection, while mutation of its immunoreceptor tyrosine-based inhibitory motifs (ITIMs)

275 o SHP-1 and SHP-2 after phosphorylation of 2 immunoreceptor tyrosine-based inhibitory motifs (ITIMs)

276 oglobulin-like (IgL) domains and cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs)

277 vation motifs (ITAMs) and those that contain immunoreceptor tyrosine-based inhibitory motifs (ITIMs).

278 latelet immunoglobulin receptor that has two immunoreceptor tyrosine-based inhibitory motifs in its c

279 ing properties, the latter being mediated by immunoreceptor tyrosine-based inhibitory motifs present

280 tation of the conserved tyrosines in the two immunoreceptor tyrosine-based inhibitory motifs prevents

281 esults in phosphorylation of the cytoplasmic immunoreceptor tyrosine-based inhibitory motifs, resulti

282 domain superfamily protein with cytoplasmic immunoreceptor tyrosine-based inhibitory motifs.

283 e cellular activation pathways via cytosolic immunoreceptor tyrosine-based inhibitory motifs.

284 dhesive and signaling properties mediated by immunoreceptor tyrosine-based inhibitory motifs.

285 yrosine-based inhibitory motif (ITIM) and an immunoreceptor tyrosine-based switch motif (ITSM).

286 s PI3K/AKT activation was dependent upon the immunoreceptor tyrosine-based switch motif located in it

287 LILRB1, which contains an immunoreceptor tyrosine-based switch motif, functions he

288 CS1-L contains immunoreceptor tyrosine-based switch motifs in its cytop

289 on in a SAP-dependent manner, requiring both immunoreceptor tyrosine-based switch motifs in the NTB-A

290 contains cytoplasmic tyrosine-based motifs, immunoreceptor tyrosine-based switch motifs, which resem

291 n its cytoplasmic domain whereas CS1-S lacks immunoreceptor tyrosine-based switch motifs.

292 complex contains 10 copies of a di-tyrosine Immunoreceptor-Tyrosine-based-Activation-Motif (ITAM) th

293 Clustering of immunoreceptors upon association with multivalent ligand

294 al features of SLP-76 to selectively support immunoreceptor versus integrin signaling, and provide ev

295 tical for signal initiation by Ag-stimulated immunoreceptors, we constructed a series of single-chain

296 ing lymphocyte activation molecule family of immunoreceptors, which self-associates, forming an ortho

297 Thus, Draper seems to be an ancient immunoreceptor with an extracellular domain tuned to mod

298 in-containing molecule 3), and TIGIT (T-cell immunoreceptor with immunoglobulin and ITIM domains) act

299 arliest events of immune cell activation via immunoreceptors with unexplained specificity and speed.

300 The NKG2x/CD94 family of C-type lectin-like immunoreceptors (x = A, B, C, E, and H) mediates surveil