ライフサイエンスコーパス: immunoregulation

1 involved in myogenesis, cell migration, and immunoregulation.

2 rrier function, innate bacterial killing, or immunoregulation.

3 m, and sex-specific epigenetic mechanisms of immunoregulation.

4 roduction and their emerging role in mucosal immunoregulation.

5 and play important roles in host defense and immunoregulation.

6 nts with MS, demonstrating a defect in TIM-3 immunoregulation.

7 ed secretory proteins that are implicated in immunoregulation.

8 porting our previous reports of ex vivo DBMC immunoregulation.

9 n that has functional relevance for cellular immunoregulation.

10 hanism involving apoptotic cell-deletion and immunoregulation.

11 upport an important role of this molecule in immunoregulation.

12 active immunization by regulating Ag-induced immunoregulation.

13 y an important role in both host defense and immunoregulation.

14 s important for both protective immunity and immunoregulation.

15 development and may be secondary to aberrant immunoregulation.

16 functions in inflammation, host defense, and immunoregulation.

17 atory molecule for T cells that functions in immunoregulation.

18 al T cell tolerance induction and peripheral immunoregulation.

19 ural killer T cells (iNKTs) are important in immunoregulation.

20 al work in adult animal species dealing with immunoregulation.

21 Fox) transcription factors play key roles in immunoregulation.

22 gammadelta T cells play an important role in immunoregulation.

23 luated whether SPr expression was subject to immunoregulation.

24 critical elements in cytokine signaling and immunoregulation.

25 icated in cell adhesion, cell signaling, and immunoregulation.

26 nd identified pathways of intestine-specific immunoregulation.

27 ses the role and importance of PPAR gamma in immunoregulation.

28 that control cytokine production can affect immunoregulation.

29 NF-alpha, and could be important for mucosal immunoregulation.

30 eproduction, lactogenesis, tumorigenesis and immunoregulation.

31 GH has been shown to influence immunoregulation.

32 , especially myonuclei, suggesting disturbed immunoregulation.

33 y in view of its recently described roles in immunoregulation.

34 ce of lung lymphocyte apoptosis in pulmonary immunoregulation.

35 is DC subset may play a role in farm-related immunoregulation.

36 us functionality of MSCs in inflammation and immunoregulation.

37 nceptualizing mechanisms of host defense and immunoregulation.

38 a framework for appreciating microbe-induced immunoregulation.

39 innate immune cell-mediated host defense and immunoregulation.

40 in promoting some aspects of MSC-associated immunoregulation.

41 eration of T cells and provides insight into immunoregulation.

42 testinal microbiota and promotion of mucosal immunoregulation.

43 n the fields of stem cells, biomaterials and immunoregulation.

44 ular interactions, which result in divergent immunoregulation.

45 veral pathways involved in cell division and immunoregulation.

46 ntibodies and mucosal immunity as well as to immunoregulation.

47 ll subsets are critical for host defense and immunoregulation.

48 gamma receptors (FcgammaR) provide important immunoregulation.

49 hanism is unknown but is believed to involve immunoregulation.

50 processes, as well as tissue remodeling and immunoregulation.

51 ng that Vitamin D has a nonclassical role in immunoregulation.

52 n programs relevant to tissue remodeling and immunoregulation.

53 t recipients to test for enhanced markers of immunoregulation: (1) flow-cytometry immunophenotyping o

54 cent discoveries in both host protection and immunoregulation against gastrointestinal nematodes, pla

55 by which thymoglobulin may generate durable immunoregulation and allograft survival.

56 due to H. pylori is associated with loss of immunoregulation and alteration of several cytokines and

57 t may have important implications for T cell immunoregulation and autoimmunity.

58 NKL is involved in multifaceted processes of immunoregulation and bone resorption such as they occur

59 cells would have important implications for immunoregulation and cellular therapy.

60 HD1 mutation indicate its important roles in immunoregulation and cerebral vascular hemeostasis.

61 ing evidence suggests that a balance between immunoregulation and deletion of donor alloantigen react

62 s of IL-11 are achieved via a combination of immunoregulation and direct neuroprotection.

63 ion to address their actual contributions to immunoregulation and disease.

64 gene is important for T lymphocyte-mediated immunoregulation and has been associated with several au

65 inct T-helper subsets is critical for normal immunoregulation and host defense.

66 topes may contribute to the understanding of immunoregulation and immunodiagnosis.

67 s are likely to play broad-spectrum roles in immunoregulation and immunopathology by influencing MIF

68 des proteins which play an important role in immunoregulation and in disease susceptibility.

69 shown to be an active participant in mucosal immunoregulation and inflammation.

70 sent a molecule of significant importance in immunoregulation and might be a therapeutic target in pa

71 ry demyelination via a unique combination of immunoregulation and neuroprotection.

72 as also provided the basis for defining host immunoregulation and parasite-evasion strategies, helpin

73 income countries are associated with failing immunoregulation and poorly regulated inflammatory respo

74 ults suggest a novel aspect of CD24-mediated immunoregulation and represent, to our knowledge, the fi

75 A link between immunoregulation and self-nonself discrimination has eme

76 trate a novel pathway for IFN-gamma-mediated immunoregulation and suggest that IFN-gamma-dependent su

77 likely to perform distinct functions in both immunoregulation and the recognition and removal of ACs.

78 riate animal model is required to understand immunoregulation and to address the role of immunogeneti

79 memory T cells, may condition the imbalanced immunoregulation and tolerance in NOD T cells.

80 d, and we identified three major networks of immunoregulation and tolerance.

81 nd produce IL-4 and IFN-gamma play a role in immunoregulation and tumor rejection.

82 ctive intestinal peptide (VIP) has a role in immunoregulation, and has been identified as a molecule

83 important role in the normal morphogenesis, immunoregulation, and homeostatic mechanisms in both nor

84 s both required for lymphocyte selection and immunoregulation, and is a prominent outcome of immune a

85 host defense, tissue maintenance/remodeling, immunoregulation, and many other biologic responses.

86 which participates in cholesterol transport, immunoregulation, and modulation of cell growth and diff

87 roles of apoE in atherosclerosis regression, immunoregulation, and neurodegeneration.

88 ociated with JAK/STAT signaling, chemotaxis, immunoregulation, and NLRP3 inflammasome activation in L

89 blood, marrow, and allograft) signatures of immunoregulation are promoted by conversion from tacroli

90 f Crete became host to lively discussions on immunoregulation as experts from around the world gather

91 ine model may be useful for studying mucosal immunoregulation as it relates to the pathogenesis and t

92 of great interest for their potential use in immunoregulation, as well as for other biological proper

93 h node DC subsets revealed a predominance of immunoregulation-associated CD11c+ B220+ plasmacytoid DC

94 ld appear to have important implications for immunoregulation at homeostasis and in immune-mediated d

95 genetically susceptible hosts with defective immunoregulation, bacterial clearance, or mucosal barrie

96 e a framework for developing microbiome- and immunoregulation-based strategies for prevention of stre

97 in the expression of markers associated with immunoregulation between CD11b(+)Gr-1(+) cells of both t

98 ines are critical for normal cell growth and immunoregulation but also contribute to growth of malign

99 nd its synthetic compound AM80 play roles in immunoregulation but their effect on mucosal autoimmunit

100 Loss of immunoregulation by CD1d-restricted NKT cells could expl

101 IL-12 family perform essential functions in immunoregulation by connecting innate and adaptive immun

102 tors, we examined how apoptotic cells induce immunoregulation by dendritic cells (DC).

103 cell differentiation and novel mechanisms of immunoregulation by IL-18 and PGE2.

104 istic insights into HDAC inhibition-mediated immunoregulation by induction of IDO.

105 al a novel function of adhesion molecules in immunoregulation by MSCs and provide new insights for th

106 Significance of IL-10 in host immunoregulation by skin stage schistosomula of S. manso

107 It also modulates immunoregulation, cell growth and differentiation and th

108 ing Alzheimer's disease, cognitive function, immunoregulation, cell signaling, and infectious disease

109 ortant role for LFA-1/ICAM-1 interactions in immunoregulation concurrent with lymphocyte migration th

110 Compromised immunoregulation contributes to obesity and complication

111 This form of immunoregulation could explain the "exhaustion" of T cel

112 ion of mucosal barrier function, or altering immunoregulation (decreasing proinflammatory and promoti

113 of chronic IFN-I signaling and mechanism of immunoregulation during an established persistent virus

114 ve profound effects on the microbiota and on immunoregulation during early life that persist into adu

115 nce of immune deviation or other evidence of immunoregulation, elicited by endogenous Escherichia col

116 In this study we demonstrate a new form of immunoregulation: engagement on CD4(+) T cells of the co

117 drive Th1 differentiation and interfere with immunoregulation established by alloreactive natural CD4

118 findings demonstrate that perforin-mediated immunoregulation functions in trans and are consistent w

119 A role for gammadelta T cells in immunoregulation has been shown in a number of studies,

120 mucosal homeostasis; however, their role in immunoregulation has been unknown.

121 This immunoregulation has potential importance for the treatm

122 Conditions consistent with tolerance or immunoregulation have been observed in experimental Cand

123 nal, mechanistic data for dysregulated TIM-3 immunoregulation in a human autoimmune disease and sugge

124 y to Mycobacterium leprae and is a model for immunoregulation in a human disease.

125 and of Gal9 in T-regs contribute to impaired immunoregulation in AIH by rendering effector cells less

126 mmatory challenge, suggesting that defective immunoregulation in AIH might result not only from reduc

127 We investigated whether impaired immunoregulation in AIH results from reduced expression

128 vations provide new mechanistic insight into immunoregulation in allograft recipients relative to obe

129 the urgency of the need for basic studies of immunoregulation in both adaptive cell lineages and inna

130 ore, we suggest that loss of miR-29-mediated immunoregulation in CD DCs might contribute to elevated

131 into the characterization of B cell-mediated immunoregulation in clinical tolerance and show a potent

132 esponse in leprosy has provided insight into immunoregulation in human infectious disease.

133 d reflected amnion is a unique mechanism for immunoregulation in human pregnancy akin to that establi

134 e results suggest an intrinsic alteration in immunoregulation in RA and have implications for potenti

135 s a critical gap in our understanding of the immunoregulation in response to repeated exposure to A.

136 eting PERK may provide a means for selective immunoregulation in the context of ER stress without dis

137 is able to exploit an endogenous pathway of immunoregulation in the host.

138 definitive evidence for a basic mechanism of immunoregulation in the oral mucosa.

139 is increasingly being appreciated to affect immunoregulation, inflammation and pathology.

140 echanistically was characterized by enhanced immunoregulation involving alterations in CD4+ T cells,

141 t LLR patients have important alterations in immunoregulation involving CD4(+)CD25(hi)FoxP3(+) Tregs.

142 Negative immunoregulation is a major barrier to successful cancer

143 icrobial input from the environment to drive immunoregulation is a major component of the beneficial

144 It is likely that this selective immunoregulation is dependent on the nature of the APC a

145 A fundamental problem in immunoregulation is how CD4(+) T cells react to immunoge

146 We revealed that in mMSCs IFN-gamma-induced immunoregulation is mediated by early phosphorylation of

147 This failure of immunoregulation is partly attributable to a lack of exp

148 t the relationship of their action to T cell immunoregulation is unknown.

149 role in the cytokine network responsible for immunoregulation, is also known to contribute to endothe

150 f antigens and have a requirement for active immunoregulation, largely T cell mediated, that promotes

151 Thus, the net effect of immunoregulation may be either neuroprotective or neurod

152 Immunoregulation may provide more insight into this phen

153 ng that transplantation tolerance and normal immunoregulation may represent a unique form of Th2-like

154 oire and the mechanisms of antibody-mediated immunoregulation observed in allergy models will lead to

155 rting evidence for NK cell-mediated negative immunoregulation of activated T cells during daclizumab

156 portant physiological role that GrK plays in immunoregulation of adaptive immunity in humans and indi

157 otes both the generation of autoimmunity and immunoregulation of adaptive immunity.

158 )CD25(+) T reg) cells play a key role in the immunoregulation of autoimmunity.

159 f these src-family kinases in FCRL4-mediated immunoregulation of B cells in the context of previously

160 prominent cytoskeletal protein, LEK1, in the immunoregulation of DC functions; specifically cytokine

161 e for novel roles for c-Src and STAT3 in the immunoregulation of DCs.

162 abetes of NOD mice, insulin-based preventive immunoregulation of diabetes in man is not yet possible.

163 acious immune response and the potential for immunoregulation of effector cells at the local site of

164 e to lymphomagenesis by inducing (1) loss of immunoregulation of Epstein-Barr virus-infected B cells

165 nable neuroprotective strategy is to harness immunoregulation of glial and retinal ganglion cell fate

166 stic and prognostic data regarding effective immunoregulation of HIV-1.

167 Immunoregulation of lymphocytes and macrophages in the p

168 cells appear to play a critical role in the immunoregulation of stress states, renal cell therapy du

169 f MS may function in part by restoring TIM-3 immunoregulation of T cell function.

170 on by human T cells might play a role in the immunoregulation of T cell responses.

171 selected individuals likely involves failed immunoregulation of the T-cell-RGC axis and is thus a di

172 are not associated with antagonistic type 2 immunoregulation of type 1 responses in liver.

173 owever, it remains unknown whether MSCs have immunoregulation on Tfh cells.

174 bility alleles at loci expected to influence immunoregulation (PTPN22, CTLA4, and IL2RA) did not diff

175 These findings indicate that an induction of immunoregulation, rather than simple lymphocyte depletio

176 ivotal processes, such as liver development, immunoregulation, regeneration, and also fibrogenesis.

177 are beginning to be appreciated as agents of immunoregulation that can modulate antigen presentation,

178 that potentially contribute to the impaired immunoregulation that is characteristic of AIH.

179 This is postulated to be due to immunoregulation that prohibits a more profound Candida-

180 autoimmunity rather than the risk of failed immunoregulation that results in islet destruction.

181 understand the mechanism of this failure of immunoregulation, these results suggest that similar pro

182 offer new insights about mucosal-derived DC immunoregulation through SIgA opening new therapeutic ap

183 nations acting at multiple sites of aberrant immunoregulation to achieve disease quiescence and immun

184 This form of immunoregulation was absent after sensitization of Fas l

185 Ameliorating autoimmunity through immunoregulation was assessed by adoptive transfer.

186 Immunoregulation was associated with localization of B c

187 Mechanistically, DPSC-induced immunoregulation was associated with the expression of F

188 findings establish a new paradigm for innate immunoregulation, whereby magnesium plays a critical reg

189 llular allograft acceptance show evidence of immunoregulation which is not due to immune deletion or

190 sms, including clonal depletion, anergy, and immunoregulation, which act in a synergistic fashion to

191 tinal mucosa represents a novel mechanism of immunoregulation, which contributes to the generation of

192 ancer-related biological pathways, including immunoregulation, which may influence susceptibility to

193 UF1-induced immunoregulation, which safeguard against proinflammator

194 iology, such as stem cell niche, homing, and immunoregulation, will also be discussed.

195 es in pathways involved in proliferation and immunoregulation, with an overall pattern that bears hal

196 adelta T cell-dependent cardiac inflammatory immunoregulation, with increased numbers of CD3(+)CD4(+)

197 ated by low doses of IL-2 (ld-IL-2) inducing immunoregulation without immunosuppression and establish