ライフサイエンスコーパス: impact

1 limited, with clinical trials having little impact.

2 of different containment measures and their impact.

3 3 x more strain energy than the horn during impact.

4 mechanistic explanation for Lon's widespread impact.

5 th huge strain diversity and a high clinical impact.

6 unlikely to have a measurable physiological impact.

7 mproving projections of future global change impacts.

8 populations of naturalised species and their impacts.

9 acy testing and quantification of non-target impacts.

10 al, economic implications, and environmental impacts.

11 Such fragmentation has been reported to impact a small fraction of the tRNA pool and thus presum

12 r layer between droplet and substrate during impact, a balance of air compression and drainage within

13 asparagine(N)-linked carbohydrates (glycans) impacts affinity.

14 allowed for a 4 to 8 times larger projected impact against obesity than would be achieved though ref

15 ock-recrystallised monazite yields a precise impact age of 2229 +/- 5 Ma, coeval with shock-reset zir

16 cognitive architecture and human nature that impacts all of us.

17 However, impact and functional relevance of these modifications a

18 orests of the HRL have experienced low human impact and still constitute large tracts of contiguous f

19 therapies for this disease of high economic impact and the reported regenerative and antibacterial e

20 However, the impact and underlying mechanisms of HIV Tat in KSHV-infe

21 Predicted microbial functions were also impacted and network analysis revealed a greater level o

22 Here we show that impact angle and direction can be diagnosed by asymmetri

23 Notably, this increase in impact arises largely from diagnosis of TB amongst those

24 s COVID-19-related deaths, assuming relative impact (as relative risks [RRs]) of the COVID-19 pandemi

25 There are currently limited life cycle impact assessment methods existing for assessing impacts

26 citizen science approaches into the regional impact assessment of OMPs.

27 rm, led by the ELIXIR EXCELERATE Quality and Impact Assessment Subtask in collaboration with the ELIX

28 monitoring, especially with potential future impact at the POC settings.

29 here that at low doses these SCFAs directly impact B cell intrinsic functions to moderately enhance

30 ize recent work that suggests that H(2)S/RSS impacts bacterial survival in infected cells and animals

31 This suggests that 1,5-(PP)(2)-InsP(4) impacts beta-cell activity by regulating granule localiz

32 erate Nrf2 activation by disruption of Keap1 impacts bone metabolism.

33 s of early seed developmental transition and impact both seed size and quality in rice.

34 alone induced substantial T-cell depletion, impacting both conventional T cells (T(conv)) and T(regs

35 rnally, there are a number of ways to reduce impact by decreasing travel and energy use, as well as c

36 of triptolide biosynthetic pathway genes are impacted by a recent whole-genome triplication event.

37 f how biotic networks and coral reefs may be impacted by anthropogenic activities.

38 if they live in a media market that is more impacted by COVID-19.

39 Vitiligo is impacted by environmental triggers.

40 The NRE is impacted by extreme weather events, including recent inc

41 demonstrate that non-viral gene delivery is impacted by proteoglycan interactions and suggest the ne

42 in the future and stocked lakes may be less impacted by subsequent warming.

43 lls in layer 2/3 of mouse visual cortex were impacted by visual experience in the context of a behavi

44 osed by those claiming that one's scientific impact cannot be reduced to a single number.

45 erebrospinal fluid (CSF) samples in children impacted care of hospitalized neonates and young infants

46 ans male rats received a controlled cortical impact (CCI) over the caudal forelimb area (CFA) of the

47 regulatory step in signal transduction that impacts cell death and inflammatory signaling downstream

48 improve oral health, it may be effective at impacting CHD incidence in only certain groups of people

49 These differences are likely to impact colonization resistance through lantibiotic expre

50 This recent impact creates a need to make these techniques and their

51 plant growth, and its availability strongly impacts crop yield.

52 Dietary lipids impact development, homeostasis, and disease, but links

53 Here we present U-Pb ages for impact-driven shock-recrystallised accessory minerals.

54 cal diversity is and how its many dimensions impact ecological and evolutionary processes.

55 ytime (DTW) and night-time warming (NTW) may impact ectothermic animals and their interactions differ

56 oice of EV isolation procedure significantly impacts EV yield from human serum, together with the pre

57 Although environment has undeniable impact, evidence suggests that genetic factors play a si

58 lesterol biosynthesis pathway may negatively impact fish growth due to its large energy expenditure,

59 and diminishing natural resources negatively impacts food security.

60 Previous studies have estimated cranial impact forces to be up to 3400 N during ramming, and pri

61 provide systematic evidence of environmental impacts from food fraud, our results also highlight the

62 We propose that basin-impact-generated hurricane-force winds created sediment-

63 -salmonid disease that has resulted in major impacts globally.

64 a world of longer, healthier lives, the 2030 Impact Goal is anchored in an understanding that to achi

65 A thorough assessment of their impact has been hampered by a lack of methodology to mea

66 Yet, their comparative health and economic impacts have not been quantified, in particular, tiered

67 Diet can greatly impact health, while caloric restriction and fasting hav

68 fluenced common variation in telomere length impacts hematologic traits in the population.

69 re is emerging evidence that stress not only impacts high-order regions of the brain, but may affect

70 he dimensions of vessel elements in Populus, impacting hydraulic conductivity.

71 hat mediates drug resistance and confirm its impact in BRAF, EGFR, HER2 and MEK1.

72 ect on NEP in conifer forests but a negative impact in deciduous forests.

73 Because of its impact in the immune system, we investigated the role of

74 iation of variants with predicted functional impact in ~ 1300 additional Utah suicides unrelated to t

75 al and modeling approaches to elucidate such impacts in flow-electrode capacitive deionization (FCDI)

76 ion emplaced the faculae in a brine-limited, impact-induced hydrothermal system.

77 antigenic mutations that allow immune escape impact influenza epidemic dynamics at the population lev

78 Rationale: The IMPACT (Informing the Pathway of Chronic Obstructive Pul

79 nt work suggests that cholesterol metabolism impacts innate immune responses against infection.

80 crucial phenotypic traits that have greatly impacted insect behavior, physiology, and evolution.

81 fore investigated whether expression of CD73 impacts intracellular NAD(+) content and NAD(+)-dependen

82 esponse to nutrient limitations and how this impacts invasion of the metapopulation as a whole.

83 Mitigating these negative impacts is achievable, and LLIN distributions in particu

84 Nuclear war, beyond its devastating direct impacts, is expected to cause global climatic perturbati

85 gen received during this process, which thus impacts its final properties.

86 Theranostic compounds are likely to impact many cancers in the near future, not only through

87 Single-cell sequencing (SCS) has impacted many areas of cancer research and improved our

88 ific-activity, and antigen-site density most impacted median survival.

89 t-KT infections are common and substantially impact mortality and DCGF, even in the modern era.

90 sures, and models projecting their potential impact, need to look beyond the symptomatic cases if the

91 t chronic endothelial inflammation adversely impacts niche activity and HSC function which is reversi

92 rience working on groundwater quality issues impacting nonpublic water wells in Kansas.

93 The structure of this network impacts not only the socioeconomic development of the co

94 xpand the list of epigenetic regulators that impact nuclear morphology.

95 and respiratory illnesses, with a monetized impact of $8.1 million-only 2-4% of the new results attr

96 We profiled the impact of 22q11.2 CNVs on neurobehavioral measures relev

97 lic blood pressure, largely disregarding the impact of a healthy lifestyle in mitigating CHD risk.

98 In this study, we measured the impact of a sanitation intervention (dual-pit latrines,

99 We reviewed the impact of a universal face masking policy on respiratory

100 all, the results of this study show that the impact of acidification of natural waters on Fe availabi

101 Impact of additive EBL was assessed using 20 3-factor fi

102 nal statistical analyses to characterize the impact of age on the overall changes in the systemic inf

103 ese results show a significant physiological impact of amylin/calcitonin signaling in CTR-POMC neuron

104 Moreover, the model was used to predict the impact of an additive (chain capper and intercalator) on

105 The impact of atrial/SAN-selective ablation of Galpha(o) or

106 in a cross-site evaluation that assessed the impact of BEST activities on three main areas: (a) train

107 The burden of disease and economic impact of breast cancer is intensifying in LMICs.

108 Additionally, the impact of C-reactive protein (CRP) and platelet count wa

109 To directly assess the impact of cellular p53 status on CRISPR-Cas9 screen perf

110 s induced by caAKT1 and c-Myc and reveals an impact of cellular status on initiation of lineage plast

111 Previous studies have mostly assessed the impact of cis and trans effects at the gene level.

112 s worldwide, a crucial step in assessing the impact of climate change on imperiled turtle species.

113 ribe 156 cases over 5 years and evaluate the impact of clinical interventions using virological and p

114 Here we study the impact of confined and controlled swine farm environment

115 provide novel therapeutics to alleviate the impact of costly, chronic diseases such as obesity and s

116 iscale mathematical model to investigate the impact of cross-talk between tumor cell- and endothelial

117 We compared the impact of distance presenting binocular VA and uniocular

118 Here, we investigate the impact of DNA damage response and repair on 3D genome fo

119 on demand TDF/FTC for HIV prevention and the impact of doxycycline post-exposure prophylaxis (PEP).

120 here in the world and show a strong positive impact of drier soils on convection within mature MCSs.

121 has involved examining the potential causal impact of educational attainment (schooling years) on a

122 This study reports an evaluation of the impact of extending the shifts of nurses and health care

123 This study assessed the impact of fatty acid (FA) type, phospholipid concentrati

124 This study explored the impact of gold nanoparticles on the metabolic activity a

125 Here, we focus on the impact of H3 variants on various facets of development.

126 in the community also mitigated the adverse impact of housing damage on functional status, suggestin

127 In this study, we sought to evaluate the impact of implantable cardiac monitoring (ICM) in the pr

128 The impact of implementing different vaccine strategies for

129 The impact of inhalable fine particulate matter (PM(2.5), ae

130 (BNMs), complemented by the analysis of the impact of interictal spikes and fitting to the neuroimag

131 These findings may help assess the impact of interventions that improve access to treatment

132 n assessment strategy to measure quality and impact of its entire training portfolio.

133 These findings suggest a clinically relevant impact of IVIg on monoclonal antibody clearance and indi

134 We sought to elucidate the functional impact of L6CT projections from the primary visual corte

135 dental studies assessing the prevalence and impact of limitations in design, conduct, analysis, and

136 e of the downturn in the global economy, the impact of living in quarters among families who are the

137 utcomes, predictors of down-staging, and the impact of LRT in patients with beyond-MC HCC from the U.

138 tterns in rRNA, and highlight a differential impact of m(4)C methylation on prokaryotic ribosomes and

139 We evaluated the impact of maternal HIV infection on the burden of RSV am

140 ue in large-scale population and explore the impact of menopausal and HER2 status on CTS5 model.

141 d specialist palliative care to minimize the impact of metastatic bone disease on physical functionin

142 eving a better understanding of the fate and impact of micro- and/or nanoplastics (MP/NP) on diverse

143 ence plant growth, little is known about the impact of microbial diversity on plant fitness trade-off

144 ctor, the first web server for assessing the impact of mutations on m7G status, and the first databas

145 restored, indicating a negligible long-term impact of nitrogen oxides on the catalytic properties of

146 ected rhesus macaque (RM) model to study the impact of opioids on HIV reservoirs.

147 ms have evolved strategies to neutralize the impact of oxygen that can be added to and integrated int

148 In sum, these results show the broad impact of PDK4 deficiency and reveal mechanistic pathway

149 ptidoglycan transpeptidation, (c) assess the impact of peptidoglycan substrates on beta-lactam target

150 rtance at this time, to assess the potential impact of quantum computers on real problems of interest

151 Despite the more remarkable impact of saturation on O(i), polyunsaturation indicated

152 ted of two factors (scratching intensity and impact of scratching on QOL) that accounted for 64.59% o

153 rmational states and might underestimate the impact of secondary interactions.

154 -SEI), thus offering novel insights into the impact of SEI homogeneities on the structural stability

155 c brain mechanisms underlying the anxiogenic impact of sleep loss.

156 s, the aim of this study was to evaluate the impact of soft tissue grafting procedures conducted over

157 rent resection of CLM/EHD is unclear and the impact of somatic mutations has not been reported.

158 ed to derive expectations of epidemiological impact of SRs deployed at larger scales.

159 at all STR permutations and interrogate the impact of STR sequence and secondary structure on their

160 cancer cell lines provide insights into the impact of structural features on potency and chemical st

161 study provides an in-depth insight into the impact of sugar reduction reformulation on the sensory p

162 adults, providing insight into the lifetime impact of SVD genetic risk.

163 ving the extent, diversity, and quantitative impact of SVs has been challenging.

164 To comprehensively assess the impact of telomere maintenance mechanism (TMM) on clinic

165 Previous research has focused on the impact of terrorist attacks on prejudiced attitudes towa

166 The impact of the ammonium ion concentration on 10-50 mum ae

167 amined, likely due to the more severe steric impact of the dodecyloxy functionality on the stacking p

168 C-methyltransferases have been studied, the impact of the global cytosine-5 methylome on development

169 Any impact of the nearby Rothera station as a local source o

170 imize the added value and long-term societal impact of the next generation of sensor network applicat

171 Research is needed to examine the impact of the pandemic-related increase in food insecuri

172 l, and intracolon inoculations to reveal the impact of the plasmid on chlamydial colonization in dist

173 Impact of the QRSarea/LVEDV ratio on the association bet

174 The impact of these highly lipophilic sensors has, however,

175 Our study aims to explore the differential impact of this pandemic on clinical presentations and ou

176 s to determine the prevalence and associated impact of tryptase genotypes on anaphylaxis in humans.

177 on a North-West to South-East cline, but the impact of unmeasured geographical confounding on genome-

178 We examined the impact of upfront small bowel resection (USBR) for metas

179 tional, mobility, and reading domains of the Impact of Visual Impairment (IVI) questionnaire.

180 constitutes an ideal system for studying the impact of WGD events on speciation and evolutionary adap

181 ing whether the magnitudes of the population impacts of abiotic, biotic, and anthropogenic drivers di

182 In addition to highlighting novel ecosystem impacts of alternate bioenergy landscapes, our results s

183 However, annual life cycle environmental impacts of crop production at county scale across mutipl

184 riant resistance may have underestimated the impacts of drought on gymnosperm-dominated forests under

185 rstand the invasiveness and future predatory impacts of geckos, and other invasive species globally,

186 Our model predicts that increasing the impacts of infanticide will increase the length of the f

187 These functional impacts of Kv2.1 depend on its level of expression, whic

188 port the use of this approach to examine the impacts of minority HIV variants on virologic response a

189 ry 23 to May 9, 2020, we illustrate that the impacts of mitigation measures are discernable from the

190 erscores the need to further investigate the impacts of multiple stressors on immune system developme

191 In this study, the impacts of pH and CaCl(2) were examined on the solution-

192 the type of electrocatalyst?(3)What are the impacts of reaction conditions (electrolyte concentratio

193 However, the long-term impacts of salinization on the terrestrial water balance

194 of microstructures that maximize the useful impacts of segregation.

195 espiratory chain defects in the bioenergetic impacts of tafazzin deficiency.

196 sks will enable evaluations of the potential impacts of TB control and elimination strategies.

197 Impacts of the main sulfur species (FeS and FeS(2) ) on

198 atient deferrals, and the secondary economic impacts of the pandemic.

199 ld, yet our understanding of the belowground impacts of this phenomenon is limited.

200 the specific integration mechanisms and the impacts of viral integration.

201 hotosynthesis, implying that the synergistic impacts of warming and biodiversity loss on ecosystem fu

202 bacterial competition is clear, the fitness impacts of wielding a T6SS are not well understood.

203 Food has a major impact on all aspects of health.

204 Impact on carbapenem use was assessed at several cut-off

205 m amount of weight loss to have a meaningful impact on cardiovascular health and survival is unknown.

206 Addition of vancomycin had minimal impact on CDI rates (data not shown).

207 KV infection in the spleen but had a minimal impact on CHIKV infection in the joint.

208 ate the M. pneumoniae genotype shift and its impact on clinical presentations, additional surveillanc

209 chlea, rather cisplatin had a dose-dependent impact on cochlear clock rhythms only after treatment at

210 lihood of dementia in older people but their impact on cognitive ageing in younger, healthy brains is

211 rs, with artifact in one quadrant showing no impact on DeltaRNFL in the opposite quadrant (P > 0.05).

212 uing ways, and they have, in general, a huge impact on electronic spectra.

213 However, its impact on endometrial cancer remains unclear.

214 argely attributed to neck elongation and its impact on feeding efficiency.

215 n inhibits target enzymes with a detrimental impact on fitness.

216 ort to prioritize variants in terms of their impact on gene expression in the brain.

217 newborns from early-onset disease, yet their impact on GI colonization and LO disease is unexplored.

218 r that elevated temperatures have a profound impact on global N cycling processes with implications o

219 with greater cohort retention but had little impact on incidence or timing of pregnancy detection.

220 nd other advanced tumors, could have a broad impact on its treatment.

221 attention has focused on acute care and the impact on long-term health is poorly evaluated.

222 quality metric methodologies to explore the impact on measured performance.

223 Vascular comorbidities have a deleterious impact on multiple sclerosis clinical outcomes but it is

224 tivity of the insulin receptor; however, its impact on pancreatic beta-cell function is unknown.

225 ethnicities, has a substantial psychosocial impact on patients and relatives, and is the leading cau

226 A significant therapeutic impact on patients with bladder cancer is found in the u

227 om cutoff thresholds will likely have little impact on population levels of first-episode psychosis.

228 k factors among patients with LVAD and their impact on postimplant outcomes using the Interagency Reg

229 stetrical injury has significant deleterious impact on recovery of the vaginal wall from pregnancy.

230 and 3, decreases in SS tend to have a larger impact on reliability in eyes with severe glaucoma (-1.2

231 g to a negligible level while minimizing the impact on sensitivity on a high-resolution Q-TOF equippe

232 n of up to 11 C-terminal residues had little impact on the agonist-induced response.

233 ies show that although climate change has an impact on the carbon fluxes of these ecosystems, the dir

234 related coronavirus 2 infection has a direct impact on the clinical outcomes of coronavirus disease 2

235 ology, but their significance has had little impact on the conceptual underpinning or practice of bio

236 , not much is known about their multifaceted impact on the exhausted CD8(+) T cell receptor (TCR) rep

237 of small-molecule catalysts has had sizable impact on the field of asymmetric catalysis in recent ye

238 d by the array may have a major facilitating impact on the field of electromicrobiology.

239 igh-energy injuries and to investigate their impact on the incidence of surgical site complications.

240 r displacing agents were evaluated for their impact on the PET brain imaging data.

241 omarkers in ICI therapy and they may have an impact on the prognostic power of PD-L1.

242 one precursors, were found to have a crucial impact on the rate of equilibration to the corresponding

243 been necessary rather than 31, with minimal impact on the recommended courses of action.

244 tracking strain assessment has a significant impact on the results.

245 al phenotype of microglia, which may have an impact on their function in health and disease.SIGNIFICA

246 However, the impact on transmission of human immunodeficiency virus (

247 he adaptive immune response and a modulatory impact on type I allergy is discussed.

248 isual impairment (VI) can have a detrimental impact on vision-related quality of life (VRQoL), but it

249 ge, such that frailty had a stronger adverse impact on younger patients.

250 To understand potential impacts on blood Pb levels (BLLs) from drinking water Pb

251 The impacts on M. smegmatis growth range from mild to severe

252 Invasive non-native species have pervasive impacts on native biodiversity, including population ext

253 ficult to quantify can have large downstream impacts on our ability to elucidate molecular drivers of

254 ified oral loading strategy (ILS) before PCI impacts on outcomes among these patients in contemporary

255 However, the impacts on post-transmission disease development and inf

256 g that high value distractors have different impacts on prefrontal and parietal regions, we designed

257 seasons have been assumed to have negligible impacts on the annual carbon balance but as data coverag

258 ct assessment methods existing for assessing impacts on the natural resource soil.

259 Forecasting storm impacts on these ecosystems requires consideration of ri

260 ated with mitigating ecological and economic impacts once nonnative species establish and spread.

261 nfluence the tumor cells themselves but also impact other cells of the tumor stroma.

262 erall, these results shed light on how mucus impacts P. aeruginosa behavior, and may inspire novel ap

263 e gene expression changes that significantly impact pathways mediating the metabolism and transport o

264 Cluster II (28 patients) - the minimally impacted patient exhibited highest levels of self-effica

265 memory-guided identity templates proactively impact perception and are associated with anticipatory s

266 te that pre-existing hereditary genetics can impact progression and survival outcomes of a future mal

267 iscern whether blood-stage parasite exposure impacts protection against homologous controlled human m

268 failure experience symptoms that negatively impact Quality of Life.

269 equent as droughts, are overlooked and their impacts remain poorly understood.

270 idation of the mechanisms by which sociality impacts reproduction.

271 e AMD, previous anti-VEGF treatments did not impact retinal vascular measurements (P = .324-.986).

272 The Scratch Intensity and Impact Scale consisted of two factors (scratching intens

273 cations overlaps with variants and adversely impacts short-read variant calling.

274 that another factor such as phylogeny might impact size estimates and comparisons.

275 th systemic and local microenvironments that impact stem cell plasticity and impair regenerative capa

276 We describe the impact that COVID-19 has had on geographically disparate

277 t but, with the exception of HvCslF6, do not impact the abundance of (1,3;1,4)-beta-glucan in mature

278 Such progress will impact the academic sector as new forms of research base

279 Several phenotypes that impact the capacity of cancer cells to survive and proli

280 s, and environmental exposures, all of which impact the resulting distribution of substitutions.

281 put into the ocean, which in turn might have impacted the marine primary productivity and organic car

282 remains unknown how SYNGAP1 loss of function impacts the development and function of human neurons.

283 tween injury and polyplex injection directly impacts the magnitude of transfection efficiency, but th

284 The choice of such representations impacts the performance and outcomes of chemical machine

285 which the quality of a predicted contact map impacts the performance of contact-assisted threading re

286 owever, how stereochemistry of carbohydrates impacts the self-assembly process remains unclear.

287 In this review, we discuss how OCM impacts the translation apparatus (composed of ribosome,

288 d their ability to detect cell-type markers, impacting their predictive value and suitability for int

289 LCA) studies that quantify the environmental impacts throughout the entire life cycle of packaging an

290 ver, it is unclear which motifs are prone to impact transcriptional regulation if mutated.

291 tRNA pool and thus presumed to not directly impact translation.

292 nt genetic data to identify CMV, which could impact treatment of up to 4% of children in the intensiv

293 To test whether loss of TMPRSS13 impacts tumor progression, TMPRSS13 was genetically abla

294 We quantify this impact under four hypothetical stewardship strategies.

295 nt of the drivers of potential alien species impacts under contrasting scenarios and socioecological

296 signed to determine if our findings directly impact vaccine effectiveness.

297 epletion of m(6)A writer METTL3 specifically impacts viral late transcripts by reducing their splicin

298 n on river transport of Hg in a heavily ASGM-impacted watershed.

299 n-like regions, future hydro-climate-related impacts will be substantially modulated by the time evol

300 little knowledge of the contributing factors impacting workload.