ライフサイエンスコーパス: impact

1 ide the economic system (e.g., environmental impact).

2 cological thresholds, and responses to human impact.

3 ntration of FL leads to decreased biological impact.

4 at interventions may be targeted for maximum impact.

5 uotients, supporting their strong functional impact.

6 ideration of both economic and environmental impacts.

7 with which to analyse its biology and health impacts.

8 estimates could play in understanding policy impacts.

9 waste management methods' climate and energy impacts.

10 ble sensor for detecting field football head impacts.

11 ectives as well as evaluate disparate racial impacts.

12 ve a substantial influence on the life-cycle impacts.

13 depend on both the level of noise and how it impacts a particular computation.

14 fucosylation, sialylation did not adversely impact ADCC.

15 ion pattern of endothelial cells and thereby impact adhesion of circulating cells.

16 tospheric aerosol injection (SAI), which has impacts analogous to those from volcanic eruptions.

17 of considering the legacy of past ecosystem impacts and how recovery or persistence of those effects

18 t and least likely to reduce the accuracy of impact assessments.

19 nd, randomised controlled superiority trial (IMPACT) at 15 National Health Service child and adolesce

20 e years (QALYs), costs, and resulting budget impact between ECHO and non-ECHO patients with HCV were

21 The range of the difference (percent) in impacts between including and excluding adaptation, irre

22 scientists and for the wider public, as they impact both the reproducibility and accessibility of res

23 ose fluctuations do not only have structural impact, but additionally a dynamical one: They cause the

24 clude that Pfr acquisition and stability are impacted by a collection of opposing allosteric features

25 ic mutational trajectories are significantly impacted by host proteostasis.

26 ttle is known about whether T cells directly impact cardiac fibroblasts (CFBs) to promote cardiac fib

27 to guide BER activity in a gene promoter and impact cellular phenotype ascribes an epigenetic role to

28 IS), which influence particle properties and impact climate, human health, and ecosystems.

29 obal EFFORTLESS S-ICD (Evaluation oF FactORs ImpacTing CLinical Outcome and Cost EffectiveneSS of the

30 Here we demonstrate a head impact detection method that can be implemented on a wea

31 types of data provides new opportunities to impact diagnostics and therapeutics.

32 es domains of the Migraine Physical Function Impact Diary (scale transformed to 0 to 100, with higher

33 reparations suggest that epithelial polarity impacts directional release.

34 al growth in source waters, and consequently impacting disinfection byproduct (DBP) formation in fini

35 ign of cellular assays, which can ultimately impact disparities in healthcare that exist in limited-r

36 The impacts, driven by projected increases in both total and

37 r, the extent and types of genetic variation impacting embryonic gene expression, and their interacti

38 (ii) We identified the variables that impact Env's glycosylation profile at sites with diverge

39 rts may foreshadow further interdisciplinary impacts for catalytic remodeling of natural products, in

40 disruption induces a cascade of events which impacts glycan biosynthesis through Hexosamine Biosynthe

41 uce tolerance and determining its behavioral impact have proven difficult.

42 As low-level, sensory processing impacts higher-order operations, such sensory anomalies

43 determine if dysbiosis of the gut microbiome impacts honeybee health, and we performed experiments to

44 et dysfunction requiring IBx had far greater impact (HR = 13.8, P < .0001).

45 er, few studies have investigated how stress impact humans raised in an overprotective manner.

46 Thus, understanding how sex impacts immunity requires the elucidation of complex int

47 pe combinations in vitro and evaluated their impact in 1,328 patients with AML who underwent HCT from

48 ng of MMP activity in vivo could have a high impact in basic research as well as in clinical applicat

49 The reduced environmental impact in high-income countries is driven by reductions

50 engineering promises to have a revolutionary impact in our societies.

51 Bycatch mortality has high population-level impacts in all three species, with shearwaters having th

52 mbient particles and to know their potential impacts in human health and radiative forcing in the air

53 Pathways leading to such impacts include mining infrastructure establishment, urb

54 t that changes in infant formula composition impact infant metabolism, and show that metabolomics is

55 apparently involved in brain development and impacts inter-individual susceptibility to injury after

56 The measurement of research impact is an essential exercise to help direct the alloc

57 Representing Sc and their radiative impact is one of the largest challenges for global clima

58 ase boundaries, yet the full extent of these impacts is unknown and thus neglected in environmental l

59 ophthalmology-related RCTs published in high-impact journals in the past 10 years.

60 in close temporal proximity to environmental impacts known to induce oxidative stress.

61 ory synaptic transmission and their function impacts learning, cognition and behaviour.

62 hat brain tissue deformation induced by head impact loading is greatest in sulcal locations, where pa

63 turbations of gene expression, with Star-PAP impacting lowly expressed mRNAs and long-noncoding RNAs

64 tation rate variation, and position-specific impact measures.

65 ation group D2 protein (FANCD2) functionally impacts mitochondrial ATP production through its interac

66 ntations of change in major land use classes impact modelled future distribution patterns.

67 sruption of Munc13 autoinhibition profoundly impacts nervous system function in vivo.

68 l activity and functional integrity of these impacted neural networks in primary progressive aphasia

69 ry research articles published in three high-impact nursing research journals in 2016 was undertaken.

70 onal, and country-level resource recovery to impact nutrient and household electricity use through 20

71 Here we infer the potential impact of 19 well-defined DCAFs in human lung adenocarci

72 nate from global wildfires ignited after the impact of a 10-km-diameter asteroid on the Yucatan Penin

73 We investigated how OA affects the impact of a cubozoan predator on their zooplankton prey,

74 To investigate the impact of a quality improvement initiative for severe se

75 Here, we investigated the impact of AbetaOs in astrocytes, a less known subject.

76 inistrative databases, and we determined the impact of adjusting for potential confounders collected

77 lized estimating equations and evaluated the impact of adjusting for surveillance within Cox proporti

78 Despite numerous studies on the impact of ageing on individual muscle fibres, the contri

79 Finally, we discuss the current and future impact of AMDs on systemic lupus erythematosus, rheumato

80 Little is known about the impact of another testing strategy, routine universal an

81 However, the direct impact of antibiotic resistance in the severity and outc

82 This study examined the impact of brief exposure to hyperoxia using diffusion te

83 ection factors for dolphin availability, the impact of bycatch on this dolphin population's conservat

84 The impact of calibration to international units/ml (CMV and

85 Due to the increasing impact of cancer on worldwide mortality, more and more a

86 eit to a lesser extent, indicating preserved impact of Cav-1 on structural plasticity of hippocampal

87 s readily detected in MKs and platelets, the impact of CK2-dependent signaling on MK/platelet (patho-

88 a infection in endemic areas; the heightened impact of combined etiologies on anemia severity is high

89 wer, but little is known about the potential impact of dam-building on the food security these rivers

90 and mechanisms of these risk factors and the impact of dehydration and electrolyte imbalance will imp

91 The impact of dentate mossy cells on hippocampal activity re

92 n tissues such as adipose and liver, but the impact of diet on acetyl-CoA and histone acetylation in

93 Overall, our results identify the impact of different risk factors, which will help in und

94 The potential impact of encapsulated molecules on the thermal properti

95 ter science, still little is known about the impact of environmental changes on an artificial chemica

96 Studies estimating the simultaneous impact of environmental variation on both selection and

97 The impact of F. johnsoniae on the tadpole surface microbiom

98 ipids study to assess for the first time the impact of fasting status on novel LDL-C accuracy.

99 The impact of Flicr is particularly marked in conditions of

100 duration and time of supply, and examine the impact of fluctuating resource availability on temporal

101 We investigated the impact of genome-wide cardiac DNA methylation on global

102 We examined the impact of germline heterozygous frameshift Chd8 mutation

103 There is a need to increase awareness of the impact of glaucoma among clinicians, patients and their

104 Outcome measures defining the impact of globalization on surgical care were developed

105 us trigger for autoimmunity, we examined the impact of granzyme A deficiency in the NOD mouse model o

106 edge, no previous studies have evaluated the impact of habituation to either low protein intake (LOW

107 rs such as NL-44, will minimize the negative impact of heat stress and increase global food productiv

108 uum is needed to achieve the full beneficial impact of HIV treatment.

109 To study the impact of hypoxic necrosis on the efficacy of antimycoba

110 e administrative data and RCT, to assess the impact of immutable time on the measurement and statisti

111 et al., builds a broad understanding of the impact of individual functional groups on the success of

112 We investigated the impact of iNKT cells in the natural history of the disea

113 This study evaluates the impact of intravascular bacterial cell numbers (ie, the

114 We examined the impact of IS drugs on gut microbiota and on the expressi

115 ring effects and computationally predict the impact of local particles' environment on the recorded I

116 our method to obtain robust estimates of the impact of local sequence features on mutation parameters

117 We analyzed the impact of mainly biogas (as well as electric and LPG) st

118 o significantly reduce or even eliminate the impact of matrix effects, even for high-throughput LC-MS

119 are defined in the mouse, yet the functional impact of most is unknown.

120 e and ischemic preconditioning, although the impact of NAC and xanthine was probably influenced by pu

121 er our understanding of the regulome and the impact of neuropsychiatric disease-associated genetic ri

122 However, the impact of non-significantly mutated genes (non-SMGs), wh

123 with chronic hepatitis C (HCV); however, the impact of nonheavy use is not clear.

124 After removing the impact of nontemperature confounders and normalizing the

125 This impact of p53 loss on 5-methylcytosine (5mC) heterogenei

126 can be reproduced in Pafah1b1(+/-) mice, the impact of Pafah1b1(+/-) on the function of individual su

127 The aim of this study was to evaluate the impact of patient-provider communication on medication a

128 ression were used to evaluate the prognostic impact of PDW.

129 al stressors may cause underestimates of the impact of pesticides, we also tested whether this pathwa

130 The impact of POCD on clinical outcomes has yet to be studie

131 Prospective studies are needed to define the impact of pretransplant sensitization on lung transplant

132 how that more than half of the environmental impact of producing the loaf of bread arises directly fr

133 sensorial attributes, aiming to quantify the impact of prolonged frying on potatoes nutrients, and th

134 of the African Diaspora and illustrates the impact of recent admixture on the diffusion of adaptive

135 A meta-analysis was performed to assess the impact of resection margin status on survival, and a reg

136 We quantified the ecological impact of riverine organic matter subsidies to glacier-m

137 Despite the broad cellular impact of SCF enzymes, important questions remain about

138 wn to be an excellent model for defining the impact of selected ferrociphenols as new therapeutic dru

139 We also analyze the impact of several biological and technical factors on th

140 We investigated the impact of six protein diets on oxidation and anti-oxidat

141 umor samples indicated a stronger regulatory impact of structural variants, as they affect more trans

142 As a control, we also evaluated the impact of succinate on (18)F-fluorocholine uptake and re

143 oncanonical Wnt pathway but also reveals the impact of such cross-talk on tumor cell phenotypes that

144 d or orexin stimulations enhance the hedonic impact of sucrose taste.

145 Our study confirms a negative impact of SVD-related morphologic brain changes on gait

146 cts should not be ignored when assessing the impact of temperature change.

147 n region for investigating the circuit-level impact of temporal patterning within a lineage.

148 In order to determine the impact of the epigenetic response to traumatic stress on

149 To describe the impact of the globalization of medical education on surg

150 This study was undertaken to address the impact of the immunogenicity derived from the Fc and var

151 Testing the impact of the individual redesigned segments revealed th

152 Here, we investigate the impact of the PHF1 N-terminal domain (NTD) on the Tudor

153 ertook a prospective study investigating the impact of the presenting anti-ADAMTS13 IgG antibody and

154 The aim of this study was to evaluate the impact of the sample reconstitution solvent composition

155 K1-binding domain (TBD), there was no direct impact of the TBD on viral replication or virulence in m

156 eveloping virus-related pathology; thus, the impact of the virome on health and disease may be even m

157 tive metabolite profiling we demonstrate the impact of the well-characterised Shiga toxin-prophage va

158 ng in both physiology and pathology, and the impact of these findings on understanding BOLD-fMRI sign

159 To investigate the potential impact of these Tau activities on MT stabilization, we i

160 area of future research is to establish the impact of this endosymbiont on vector competence.

161 ess of patients, families and staff, and the impact of using filmed narrative interviews to enhance t

162 2010 and 31 December 2015 and estimated the impact of vaccine introduction on all-cause diarrhea adm

163 We also evaluate the impact of variation in equipment setup on the accuracy o

164 d putative indirect effects of CMV, possible impact of viremia and risk factors for CMV infection in

165 NRDs are associated with slight decrease in impacts of 0.8-12.2%, 7.7-19.4%, and 7.2-18.6%.

166 0 to 2011 to determine clinical and economic impacts of cancer diagnosed within the first 3 years pos

167 In this work, we investigated the impacts of CerC16 (up to 20 mol %) on the lipid polymorp

168 capacity to assess and respond to the health impacts of climate change.

169 potted herbs whilst reducing the deleterious impacts of dense planting on product quality.

170 strated, and baseline information on current impacts of environmental variation is widely lacking for

171 ybridized, emphasizing the chronic, negative impacts of human-mediated hybridization.

172 cosystems worldwide, yet knowledge about the impacts of invasive species on bacterial communities rem

173 erventions aimed at alleviating the negative impacts of poverty on children are frequently shown to b

174 Despite disparate impacts of Setd2 and Arid1a loss on tumor development, e

175 The environmental impacts of these activities are generally accepted as ne

176 The benefits and impacts of unconventional natural gas development are re

177 stage-specific metabolic programs and their impact on adult neurogenesis are largely unknown.

178 control, the ARIA (Allergic Rhinitis and its Impact on Asthma) score ranging from 0 to 4 of the Aller

179 odians of the BBB in the normal brain, their impact on BBB integrity during ischemia remains unclear.

180 We examined the method's impact on calculated DPD, PH-LHD subclassification, hemo

181 drug response, which will have a significant impact on cancer precision medicine.

182 loid imaging results seem to have a relevant impact on caregivers.

183 , preliminary data demonstrate a substantial impact on clinical management.

184 r K(+), and pharmacology, consistent with an impact on conformation of the KCNQ pore.

185 flow intensity and pattern, with consequent impact on dand5 expression pattern and left-right (L-R)

186 hese processes can therefore have a profound impact on development.

187 Tomography has made a radical impact on diverse fields ranging from the study of 3D at

188 glycerol-induced kidney-injury had strongest impact on DY-654 elimination.

189 2 decades ago, these discussions had little impact on epidemiologic practice.

190 Plasmodium parasitemia had no impact on EVD outcomes.

191 Sample weighting approaches had little impact on field-estimated trait responses to elevation.

192 position are important for quantifying their impact on forest carbon (C) uptake.

193 ation, reversible thiol-oxidations and their impact on gene expression in Mycobacterium smegmatis und

194 The most dramatic impact on gene expression was seen for KMO, whose activi

195 ac events), use of healthcare resources, and impact on health status (quality-adjusted life-years).

196 offers hope in mitigating their catastrophic impact on life, agriculture and property.Against the bac

197 and antioxidant activity whereas a negative impact on lipase inhibitory activity was observed (p<.00

198 Greatest impact on liver function was found in animals with polym

199 designed to assess whether resistance had an impact on LLINs.

200 tomy (RPD) is gaining momentum; however, its impact on major outcomes, including pancreatic fistula,

201 about placental vitamin D metabolism and its impact on maternal circulating vitamin D concentrations

202 The DYT4 mutation had no impact on microtubule dynamics suggesting a distinct mec

203 e regulation of IL7R exon 6 splicing and its impact on MS risk.

204 ET bromodomains, which resulted in a minimal impact on MYC transcription, but did not result in a sta

205 ctrin, followed by NaV channels, with modest impact on neurofascin 186.

206 sing ancient nuclear DNA [1, 2], its genetic impact on northern and eastern parts of this continent h

207 cancer (LAEC), and to assess its independent impact on operative and oncologic outcomes.

208 ines was found to correlate directly with an impact on Pgp-derived efflux.

209 use below-average temperatures had a greater impact on phenology than above-average temperatures, the

210 ol in synthetic polymers can have a dramatic impact on polymer properties and self-assembly.

211 2 missense SZ-risk mutation had a pathogenic impact on projection neuron laminar allocation by reduci

212 sure is critical to mitigating its potential impact on public health.

213 Our findings have a significant impact on research related to MPYS-mediated human diseas

214 Somatic mutations such as CARD11 may have an impact on response to ibrutinib, may inform clinical dec

215 parts subtle if any structural or functional impact on RNAP in the absence of RIF.

216 ay radiation have great potential for a wide impact on science, and are a critical element for unrave

217 sis of (68)Ga-PSMA-11 PET/CT implied a major impact on SRT planning in 52 of 270 patients (19%) with

218 adjust to a new steady-state level, with an impact on surrounding brain cells, remains unknown.

219 lution of climate data will have the largest impact on the accuracy of biological predictions under c

220 ies of GNRs, the edge structure has a strong impact on the carrier mobility in GNRs by affecting the

221 , the extruder die did not have a measurable impact on the molecular weight reduction of waxy flour.

222 terface and interaction should have profound impact on the optimization and de novo design of new NM

223 oblem, due to its prevalence, morbidity, and impact on the quality of life.

224 onditions this diazotroph has a considerable impact on the wider carbon cycle.

225 essential enhancer-protein complexes with an impact on timely gene activation.

226 Hypoxic stress has a strong impact on tumor cell biology.

227 V71-host cell interactions and has potential impact on understanding other enterovirus-host cell inte

228 an important role in lipid homeostasis, with impact on various metabolic diseases.

229 stability of the wines without a significant impact on wine colour.

230 llular models to study epigenetic mechanisms impacting on health and disease.

231 rovide evidence that hypoxia causes economic impacts on a major fishery.

232 obally, biological invasions can have strong impacts on biodiversity as well as ecosystem functioning

233 ose effects may interact with climate change impacts on biota in the coming decades.

234 anisms by which lysine methylation signaling impacts on cell fate decisions.

235 tiple proteins, can have profound biological impacts on cells.

236 l as a screening-level assessment of climate impacts on CyanoHAB prevalence as well as potential lost

237 These differences need validation, and their impacts on disparities need more detailed investigation.

238 n, growth, and competition, as well as plant impacts on ecosystem processes.

239 virus (HIV)-infected PWUD, and assessed its impacts on first-line ART virological outcomes.

240 Gene copy number impacts on gene expression were detected with 528 genes

241 Asian-lineage ZIKV have different phenotypic impacts on host immune responses.

242 ipally with the environment, to also include impacts on human health, culture and biodiversity conser

243 Computational prediction of mutation impacts on protein stability offers a fast, economical a

244 and use a model to demonstrate the resulting impacts on regional air quality.

245 d for an improved understanding of biochar's impacts on soil NO emissions.

246 can have detrimental, costly or irreversible impacts on the environment and society.

247 budgets developed to quantify anthropogenic impacts on the nitrogen cycle do not explicitly consider

248 y-storage dielectrics will have far-reaching impacts on the sustainable energy and will be an importa

249 se, followed by "other" cancer, whereas NMSC impacted only outpatient costs.

250 This research will impact our understanding of morbillivirus-related immuno

251 il may function as a regulatory mechanism to impact ovarian cancer metastatic success.

252 We further show that neuron numbers impact overall interconnectivity as the primary reason f

253 The communication support program did not impact patients' health-related quality-of-life or the l

254 ad the largest inpatient and outpatient cost impacts per case, followed by "other" cancer, whereas NM

255 tential for changes in water availability to impact plant-pollinator interactions through pollinator

256 tool for in silico structural variation (SV) impact prediction.

257 onmental influence positively and negatively impacts programs governing myelination, and acts on myel

258 factors other than PCa-such as genetics-can impact PSA.

259 t weight loss and catabolism, and negatively impacts quality of life (QL).

260 igate across the enormous physical scales of impact ranging from individual organisms to the planet.

261 r have a different prevalence and prognostic impact remains unclear.

262 xact magnitude of the resulting carbon cycle impacts remains to be confirmed, the radiocarbon data su

263 in these patients is often mild and does not impact renal function at day 30, while infection/ sepsis

264 ty to generate a consistent immunomodulatory impact, serving as a highly important epigenetic system.

265 equired for PMW, and that TrpA1 specifically impacts siesta onset, but not night sleep onset, in resp

266 Sterilized, impacted, spill-site sediment released minor amounts of

267 nada has raised concerns about environmental impacts, such as the magnitude of air pollution emission

268 eplication in sabaeus PBMC and had a greater impact than did the CCR5 blocker maraviroc, confirming t

269 believe that this work is an example of the impact that 3D-printing will have on the future of analy

270 Grafting density and graft distribution impact the chain dimensions and physical properties of p

271 evidence suggests that genetic variation can impact the entire distribution of the expression level.

272 udied in cancers, where bromodomain proteins impact the expression of oncogenes and anti-apoptotic pr

273 de critical knowledge about the factors that impact the natural history of asthma.

274 prevalence and/or host species identity may impact the relative abundance and inhibitory properties

275 ciated with vaccine-serotype pneumococci may impact the susceptibility of children to OM progression.

276 IL-22/IL-17-producing T cells and might thus impact the T-cell responses in asthma.

277 Lymphatic vessel density did not impact the time to development of BOS or RAS in lung tra

278 Harvest time impacted the abundance of EGC, theanine and afzelechin g

279 , and complement pathway gene alteration, it impacted the composition of drusen-like deposits in pati

280 tary fibre, phenolics, and minerals, greatly impacted the flour properties.

281 scale with reduced catalyst loading without impacting the efficiency.

282 in RE, PGLO, and interleukin-18 but without impacting the RAAS.

283 Here, we report that reduced SMN function impacts the action of a pertinent microRNA and its mRNA

284 problem of interdisciplinary character that impacts the development of many functional materials and

285 Our results suggest that BDV directly impacts the kynurenine pathway, an effect that may be ex

286 asma model, it is shown that the phase shift impacts the spatial distribution of the deposited charge

287 n identified, the basis by which Cdx members impact their transcription is poorly understood.

288 families, for a better understanding of the impact this disease has on a person's life.

289 ce in the Northeast U.S., while the greatest impacts to recreation, in terms of costs, are in the Sou

290 est whether dying, untreated rods negatively impact treated, rescued rods.

291 OFD1 loss also adversely impacted upon the DSB-induced G2-M checkpoint, inducing

292 and in the endoplasmic reticulum that could impact viral entry and replication.

293 this translation mechanism might selectively impact viral protein synthesis, suggesting that an NP-me

294 demonstrate here the use of liposome rupture impact voltammetry for the qualitative detection of mode

295 Americans, women, and minorities-its overall impact was modest in comparison with the gaps present be

296 The impact was more marked at the flower-rich site (all colo

297 rry jams, minimising essential oil's sensory impact, was evaluated in this work.

298 include market goods and services (economic impact), whereas externality costs include effects outsi

299 numerous studies claiming transgenerational impacts, with little compelling evidence.

300 no attention is placed on the environmental impacts within NRDs.