ライフサイエンスコーパス: impact on

1 13 typical TOC techniques and assessed their impact on a number of critical factors such as LN transp

2 y disfiguring and has a substantial negative impact on a patient's quality of life.

3 e the evolution of the entrained air in drop impact on a wide range of liquids, using ultrafast X-ray

4 ry organic aerosol (SOA) can have a profound impact on aerosol growth and size distribution dynamics.

5 Wildfires have a significant adverse impact on air quality in the United States (US).

6 Food has a major impact on all aspects of health.

7 Sex had an impact on all beta-cell responses, with male animals exh

8 es is a ubiquitous phenomenon with a massive impact on all living organisms, shaping the world around

9 this interaction entails the most functional impact on an exercising human.

10 ing the solidification of a droplet while it impacts on an undercooled surface.

11 erum kinetics and their in vitro and in vivo impact on anaphylaxis.

12 oscopic transport properties, with potential impact on applications ranging from functional inks to n

13 protection against secondary infections, its impact on autoinflammatory diseases, associated with inf

14 To begin to understand how CPSs have an impact on Bacteroides-phage interactions, we isolated 71

15 irable aromas when hydrolyzed, could have an impact on beer aroma profiles.

16 trict prospective planning, with deleterious impacts on behavior.

17 rent conditions, are expected to cause major impacts on biodiversity in most socioecological contexts

18 tiatives are developing frameworks to assess impacts on biodiversity.

19 critical quality attribute (CQA) with direct impact on biological activity.

20 ace temperature, and discuss their potential impact on biological productivity in the tropical North

21 n of individual cells and have an increasing impact on biomedical research.

22 To understand potential impacts on blood Pb levels (BLLs) from drinking water Pb

23 A favorable impact on both perceived and objective cognitive perform

24 In situ evidence of impacts on boulders on airless planetary bodies has come

25 Childhood environment can have a profound impact on brain structure and function.

26 racellular P(i) accumulation and a potential impact on Ca(2+) signaling.

27 oride exposure in enamel cells to assess its impact on Ca(2+) signaling.

28 responses has led to investigations into the impact on cancer immunotherapies, particularly with agen

29 Impact on carbapenem use was assessed at several cut-off

30 t in patients undergoing microsurgery has an impact on cardiac biomarkers and circulating microRNAs (

31 m amount of weight loss to have a meaningful impact on cardiovascular health and survival is unknown.

32 Addition of vancomycin had minimal impact on CDI rates (data not shown).

33 ient interpretation and discuss how this can impact on cell-fate decisions.

34 is review, we discuss the types ofROS, their impact on cellular processes, and their pro- and antitum

35 y 2030, vaccination alone would have minimal impact on cervical cancer mortality, leading to a 0.1% (

36 KV infection in the spleen but had a minimal impact on CHIKV infection in the joint.

37 ublic health issues with widespread, lasting impacts on children, families, and communities.

38 R-loops have both positive and negative impacts on chromosome functions.

39 n and postnatal leptin surge have a profound impact on ciliogenesis in the hypothalamus of neonatal m

40 l will enhance further assessment of vaccine impact on circulating strains, the frequency of reassort

41 to our understanding of atmospheric aerosol impacts on climate and health.

42 rowth in China may have significant negative impacts on climate change.

43 e of AMI regardless of sex, but had no major impact on clinical management and prognosis.

44 known about AUD treatment patterns and their impact on clinical outcomes in this population.

45 ate the M. pneumoniae genotype shift and its impact on clinical presentations, additional surveillanc

46 to routine primary care at scale with little impact on clinician workload and results in reductions i

47 chlea, rather cisplatin had a dose-dependent impact on cochlear clock rhythms only after treatment at

48 lihood of dementia in older people but their impact on cognitive ageing in younger, healthy brains is

49 ated state, and one that could have a direct impact on cognitive function.

50 ntested resources, as well as how assessment impacts on contest processes and outcomes, has been fund

51 veral scenario parameters showed an outsized impact on costs relative to technology parameters.

52 nal acetylation, a modification with a major impact on cytoskeletal dynamics.

53 Occurrence, risk factors, and impact on daily life of chronic pain after critical illn

54 determined clinical features of pain and its impact on daily life.

55 rs, with artifact in one quadrant showing no impact on DeltaRNFL in the opposite quadrant (P > 0.05).

56 echanisms and dynamics, which have a crucial impact on determining the copolymer microstructure.

57 exemplify how genetic mutations can have an impact on developmental trajectories, and provide a ther

58 mutated transcripts could have a significant impact on disease maintenance.

59 or changed its immunogenicity, leading to an impact on disease severity.

60 evaluated for their anticancer activity and impact on drug resistance in comparison to metal-free th

61 aracteristics of an SK channel determine its impact on early, plateau, and repolarization phases of A

62 e favored goal-directed behaviors and had no impact on eating behavior.

63 l component of MMP transport and its overall impact on ECM remodeling.

64 lives of people around the world with a huge impact on economies and societies.

65 hange; (ii) loss of megabiota has a negative impact on ecosystem metabolism and functioning; and (iii

66 ngly to savanna elephants, forest elephants' impact on ecosystems remains poorly studied.

67 n of this policy was performed to assess the impact on ED dwell time, ICU and hospital lengths of sta

68 methoxy groups had subtler, but pronounced, impacts on either ERalpha binding or MCF-7 cell prolifer

69 uing ways, and they have, in general, a huge impact on electronic spectra.

70 h sexes, we tested for immediate stimulation impact on encoding-related activity of the hippocampus a

71 However, its impact on endometrial cancer remains unclear.

72 re most sensitive to changes in intervention impact on enrolment into community-based ART delivery.

73 complexes were not affected, but there were impacts on entry, spread, and neutralization by anti-gH

74 Herbicide treatment had no significant impact on environmental outcomes, while corn and soybean

75 markers in HIV-infected individuals but the impact on estimated glomerular filtration rate (eGFR) re

76 is assembling the available evidence for PCV impact on European, North American and Australian nation

77 argely attributed to neck elongation and its impact on feeding efficiency.

78 se, whether they were preventable, and their impact on fetal and neonatal outcomes.

79 hydrological changes that may have opposing impacts on fire, including higher basin-wide precipitati

80 n inhibits target enzymes with a detrimental impact on fitness.

81 nt as a key measure to mitigate its negative impacts on food production.

82 nipulated initial colony infection to assess impacts on foraging behavior.

83 st in North American forests, owing to their impacts on forest structure and regeneration, biodiversi

84 omoting mitochondrial function; however, its impact on FRDA has not been studied.

85 cit-Hyperactivity-Disorder (ADHD), but their impact on functional connectivity (FC) remains unclear.

86 f the endosomal membrane, have a significant impact on fusion efficiency in our models.

87 ort to prioritize variants in terms of their impact on gene expression in the brain.

88 s in Enterococcus faecalis exert significant impact on gene expression.

89 The impact on gene regulation and phenotype of the respectiv

90 newborns from early-onset disease, yet their impact on GI colonization and LO disease is unexplored.

91 r that elevated temperatures have a profound impact on global N cycling processes with implications o

92 crimination reversal learning tasks, and its impact on gray matter was measured.

93 ts metastatic spread of cancer cells without impact on growth of the primary tumor.

94 ngly paying close attention to sleep and its impact on health and wellness as a measure of critical v

95 tions is crucial as they have a considerable impact on health-care systems and society as a whole bec

96 IAV shedding from tonsils, which may have an impact on host-to-host transmission.IMPORTANCE Influenza

97 terize a regulatory circuit and quantify its impact on host.

98 indicating that environment can have a large impact on Hsp90 evolution.

99 owledge on genes that regulate LTL and their impact on human health and disease.

100 vanced over the past decade, but the largest impact on human health should be achieved with the trans

101 Gs) in human gut microbiota have significant impact on human health.

102 of Malaysia have been studied along with the impact on human health.

103 n and transforming warfare, the horse had an impact on human history with no equivalent in the animal

104 ams must be employed to minimize the adverse impacts on human health and environment.

105 s that ecosystems support, and ultimately to impacts on human health and society.

106 Drought has many known deleterious impacts on human health, but little is known about the r

107 molecule additives (excipients) with unclear impacts on human physiology, drug safety, and response.

108 rkov cohort models were used to estimate the impact on IHD burden and health equity, as well as the c

109 reduction is not feasible without a negative impact on image quality and lesion detectability.

110 e immunomodulatory drugs and will have major impacts on immuno-oncology.

111 with greater cohort retention but had little impact on incidence or timing of pregnancy detection.

112 (AMPK) and mitigates steatosis; however, its impact on ischemia-reperfusion injury and regeneration i

113 nd other advanced tumors, could have a broad impact on its treatment.

114 cade, the number of reports of ocean warming impacts on kelp forests has risen sharply.

115 The baking atmosphere has a significant impact on L* and a* colour values of bread.

116 ervical (50.5%) dystonia, with less clinical impact on laryngeal dystonia.

117 The level of mosaicism has an impact on laterality and number of tumors.

118 nt oncogene, with both positive and negative impacts on leukemogenesis, which requires the action of

119 ncreasing variants was proportional to their impact on lipid levels and partially overlapping with a

120 ing aging and metabolic alterations, but its impact on liver cancer had been unclear.

121 sed expression of hepatocyte markers with no impact on liver progenitors, other endodermal lineages,

122 asions have the potential for large negative impacts on local communities and ecological interactions

123 attention has focused on acute care and the impact on long-term health is poorly evaluated.

124 ations is increasingly being recognized, the impact on long-term survival remains unclear.

125 Diagnosis of an ECI had no substantial impact on long-term survival, health, or social/educatio

126 lymphoblastic leukemia (ALL) to 90%, but its impact on long-term toxicity remains unknown.

127 on in particular polymorphisms, and possible impact on lung function, have never been investigated in

128 The impacts on M. smegmatis growth range from mild to severe

129 Their molecular microstructures have direct impact on macroscopic properties and dictate end-use app

130 The greatest impact on malaria burden could be as a result of interru

131 nce of genitourinary birth defects and their impact on male infertility.

132 heatwaves, can have severe and long-lasting impacts on marine ecosystems, fisheries and associated s

133 n the United States (US) to lead to negative impacts on marine populations and support consumption of

134 s another player through which BCR signaling impacts on MCL cell survival.

135 quality metric methodologies to explore the impact on measured performance.

136 Chronic peer victimization has long-term impacts on mental health; however, the biological mediat

137 utic targets, we aimed to characterize their impact on metabolism using comprehensive metabolomics da

138 To predict thermal impacts on migratory riverine populations, we first expa

139 redicted regulatory function and significant impact on modulation of the host immune response.

140 ten reveals missense variants, for which the impact on molecular function and subsequent roles in can

141 A surgical intervention's impact on mortality cannot be assessed in this study, as

142 nity service in London (UK), but there is no impact on most outcomes for this population group.

143 NMDAR ablation in corticolimbic interneurons impacts on mPFC and ventral hippocampus functional conne

144 Vascular comorbidities have a deleterious impact on multiple sclerosis clinical outcomes but it is

145 tility and fish survival, but has no visible impact on muscle growth in juvenile and adult zebrafish

146 Invasive non-native species have pervasive impacts on native biodiversity, including population ext

147 ountries can have both positive and negative impacts on native wildlife populations at different scal

148 The simulated impact on near-surface climate properties at both the re

149 expansions, the resulting patterns and their impact on neutral diversity remain poorly understood.

150 (NMJ), the output of motor neurons, but its impact on NMJ repair remains unknown.

151 elective surgeries had an adverse emotional impact on non-HCWs.

152 tors that have sustained direct and indirect impact on nutrition.

153 We aimed to characterize the COVID-19 impact on NYC resident physicians.METHODSIRB-exempt and

154 re small non-coding RNAs that can have large impacts on oncogenic pathways.

155 uring perinatal period, can have a life-long impact on organismal development and physiology.

156 Our results have direct impact on other branches of physics and material science

157 ficult to quantify can have large downstream impacts on our ability to elucidate molecular drivers of

158 to study the molecular epidemiology and its impact on outcome (30-day all-cause mortality).

159 erity, phenotypical context, and independent impact on outcome in patients with MVP.

160 table practice model without obvious adverse impact on outcome.

161 , and resistance patterns in NSTIs and their impact on outcomes are unknown.

162 ified oral loading strategy (ILS) before PCI impacts on outcomes among these patients in contemporary

163 <=23 weeks gestational age and calculate its impact on overall neonatal mortality rate over a 12-year

164 Pneumonia did not impact on overall survival (P=0.807).

165 fy releases from these banks, and associated impacts on ozone depletion and climate change.

166 The associated impact on P-body dynamics has relevance to regulation of

167 tivity of the insulin receptor; however, its impact on pancreatic beta-cell function is unknown.

168 ow PTEN expression levels have a detrimental impact on patient disease-free survival.

169 ention in Ebola virus disease (EVD), yet its impact on patient outcomes remains unclear.

170 ng therapeutic decision making, although its impact on patient outcomes still needs to be defined.

171 oad experienced by surgeons may have a major impact on patient safety as well as healthcare economics

172 D (after induction v intensification) had no impact on patient survival.

173 anut allergy imposes an adverse psychosocial impact on patients and caregivers, leading to frustratio

174 ethnicities, has a substantial psychosocial impact on patients and relatives, and is the leading cau

175 A significant therapeutic impact on patients with bladder cancer is found in the u

176 to hit or lead compounds can have meaningful impacts on pharmacological profiles due to significant e

177 ration can reduce P450 metabolite formation, impacts on phase II metabolism and hepatocyte protein ex

178 nmentally responsive trait that has critical impacts on plant fitness, crop yield, and reproductive i

179 , we present a meta-analysis of P limitation impacts on plant growth, physiological, and morphologica

180 o a hitherto unknown rivaroxaban effect that impacts on platelet reactivity and arterial thrombosis.

181 Most notably, telomeres have a broad impact on pluripotency and differentiation.

182 risk of individual misidentification and its impact on population abundance estimates we performed an

183 found that risk-based targeting had minimal impact on population averages or disparities and was lar

184 om cutoff thresholds will likely have little impact on population levels of first-episode psychosis.

185 However, the impacts on post-transmission disease development and inf

186 k factors among patients with LVAD and their impact on postimplant outcomes using the Interagency Reg

187 olled trials are required to assess the true impact on postoperative complications, health care assoc

188 ncrease as a consequence of COVID-19 and its impacts on poverty, coverage of essential interventions,

189 wn to many researchers, but they have a huge impact on power analyses.

190 g that high value distractors have different impacts on prefrontal and parietal regions, we designed

191 dation in the tropics can have consequential impacts on prey communities through discrete effects on

192 setting; however, they still have a negative impact on prognosis of pneumonia patients, including hig

193 the new staging guidelines and the potential impact on prognosis.

194 s and their effectiveness, side effects, and impact on psychiatric symptoms.

195 ection and treatment of diseases with a high impact on public health are best addressed in the settin

196 al for clinical actionability and a positive impact on public health(1).

197 ween oxidative stress and neuroinflammation, impacting on PVI/PNN integrity.

198 res on urinary symptoms, sexual function and impact on quality of life, as well as measurement of pro

199 authors tested whether the cycle-GAN had an impact on radiomic diagnostic accuracy for chest radiogr

200 stetrical injury has significant deleterious impact on recovery of the vaginal wall from pregnancy.

201 and 3, decreases in SS tend to have a larger impact on reliability in eyes with severe glaucoma (-1.2

202 strand template R-loops (head-on) had little impact on replication fork progression.

203 UCTs did not impact on reported child morbidity 2 week's prior to rep

204 The impact on RV remodeling, functional status, and quality

205 ting potentials (2 V(pp,1Hz)) had a dramatic impact on scale formation, with the impact highly depend

206 While acute administration of fasudil had no impact on seizure activity, seven weeks of treatment in

207 f molecular building blocks of life, but its impact on self-assembly and compartmentalization remains

208 g to a negligible level while minimizing the impact on sensitivity on a high-resolution Q-TOF equippe

209 owever, agricultural land use has a profound impact on SOC dynamics, and few studies have explored ho

210 obial and faunal activity) mechanisms, their impacts on soil hydrological processes and plant growth,

211 "beyond the rule of 5" compounds, has little impact on solubility when log D(7.4) measurements and ar

212 ed2 is the probabilistic modeling of variant impact on specific aspects of protein structure and func

213 the most nicotine and cannabis products but impacts on sperm epigenetics are poorly characterized.

214 ll variants can retain function due to their impact on splicing.

215 Understanding extreme weather impacts on staple crops such as wheat is vital for creat

216 These changes led to a significant impact on starch digestibility, reducing significantly t

217 pounds linked to plant defense have negative impacts on sting nematode population densities.

218 turn, microbiota dysbiosis has a substantial impact on stroke outcome by modulating the immune respon

219 ncreatic ductal adenocarcinoma (PDA) and the impact on surgical outcomes remains unclear.

220 rate of interval cancers, which can have an impact on survival and mortality (with comparable effect

221 icating that transplant rate had the largest impact on survival chose the hospital with the best tran

222 cancer referrals on cancer survival, and the impact on survival per referred patient due to delayed r

223 Given their robust impact on synaptic efficacy and neuronal signalling, neu

224 103 and CD49a with a specific focus on their impact on T cell motility during influenza virus infecti

225 The potential impact on Thai population who consumed Thai local rice c

226 affected by cancer drivers to proteins that impact on the 'hallmarks of cancer'.

227 of TRIPS-Plus standards is having a negative impact on the affordability and accessibility of medicin

228 n of up to 11 C-terminal residues had little impact on the agonist-induced response.

229 onlocal damping effect-which have a dramatic impact on the amplitude and spectral distribution of pla

230 ies show that although climate change has an impact on the carbon fluxes of these ecosystems, the dir

231 related coronavirus 2 infection has a direct impact on the clinical outcomes of coronavirus disease 2

232 ology, but their significance has had little impact on the conceptual underpinning or practice of bio

233 ity after AMPK suppression in the VMN had no impact on the counterregulatory hormone response to hypo

234 These outcomes have a crucial impact on the course of the intellectual battle between

235 studies were rated level III because of the impact on the development and popularization of this tec

236 ediate ART initiation; however, the policy's impact on the economic aspects of patients' lives remain

237 exes, which weakens the Fe=O bond and has an impact on the electronic structure.

238 Fires can have a negative impact on the environment, human health, property and ul

239 This has an impact on the estradiol signaling required for proplatel

240 , not much is known about their multifaceted impact on the exhausted CD8(+) T cell receptor (TCR) rep

241 of small-molecule catalysts has had sizable impact on the field of asymmetric catalysis in recent ye

242 d by the array may have a major facilitating impact on the field of electromicrobiology.

243 n of the X residue (Pro-10) had little to no impact on the folded chemokine structure but diminished

244 miRNA alterations have a significant impact on the formation and progression of human cancers

245 eatment of elderly patients, will have major impact on the future need for healthcare resources, incl

246 rections, and key aspects that could have an impact on the future of this field.

247 diversity of study samples, and thus have an impact on the generalizability of scientific findings.

248 The late diagnosis of cancer has a negative impact on the health care system due to high treatment c

249 ts (CNVs) are suggested to have a widespread impact on the human genome and phenotypes.

250 igh-energy injuries and to investigate their impact on the incidence of surgical site complications.

251 ar disease, randomization to ramipril had no impact on the incidence or severity of COVID-19.

252 that reviewer recommendation had the biggest impact on the linguistic characteristics of reports, and

253 ofound effect on the entire family unit, its impact on the long-term mental health of family members

254 ed in other MDS/MPN subtypes and that had an impact on the outcome of the patients.

255 We aimed to assess its impact on the outcome of the SHIFT trial (Systolic HF Tr

256 r displacing agents were evaluated for their impact on the PET brain imaging data.

257 value, which would have a positive economic impact on the poor rural communities of Morocco where it

258 Factors with a high impact on the prediction of persistence were SCORAD at t

259 omarkers in ICI therapy and they may have an impact on the prognostic power of PD-L1.

260 Predatory publishing has had a significant impact on the quality of literature in the scientific wo

261 during cold-induced sweetening (CIS) and its impact on the quality of sweet potato chips of cultivars

262 cted children has a long-term and measurable impact on the quality of the HIV-specific T cell immune

263 one precursors, were found to have a crucial impact on the rate of equilibration to the corresponding

264 n the two main forms of Cu in wine and their impact on the rate of oxygen consumption.

265 nocrystals of lead bromide, with substantial impact on the reaction outcomes.

266 been necessary rather than 31, with minimal impact on the recommended courses of action.

267 (120), and Leu(158), using OXA-48 numbering) impact on the relative levels of beta-lactones and hydro

268 tracking strain assessment has a significant impact on the results.

269 the Up states, it did not have a significant impact on the slow waves or memory performance after sle

270 ether anthropogenic pressures have a similar impact on the social structure of wild animal communitie

271 Increasing scan speed had a negative impact on the thickness, corrosion resistance, and the p

272 ugh the MZT is typically considered from its impact on the transcriptome, we previously found that th

273 urement of axon radii could have significant impact on the understanding of healthy and diseased neur

274 uence Alzheimer's disease could have a major impact on the understanding, treatment and prevention of

275 seasons have been assumed to have negligible impacts on the annual carbon balance but as data coverag

276 VEGF-C by AR may then result in differential impacts on the ccRCC metastatic destinations of VHL-wt c

277 utcomes of oral health as well as the social impacts on the elderly.

278 High temperature brings adverse impacts on the energy efficiency, and even destroys a se

279 d temporal changes in land cover have direct impacts on the hydrological cycle and stream quality.

280 The most striking individual impacts on the likelihood for FLI above 60% were observe

281 w that hurricanes have enduring evolutionary impacts on the morphology of anoles, a diverse Neotropic

282 ct assessment methods existing for assessing impacts on the natural resource soil.

283 at incorporates various sources of potential impacts on the performance of bioindicator species, incl

284 heir physicochemical properties has a strong impact on their biological activity.

285 al phenotype of microglia, which may have an impact on their function in health and disease.SIGNIFICA

286 e (ie, dry eye daily/almost daily with major impact on their life).

287 tly expressed in glioblastomas (GBM) but its impact on therapy response is still under controversial

288 rate (tumor-specific properties) have large impacts on therapy efficacy.

289 Forecasting storm impacts on these ecosystems requires consideration of ri

290 However, the impact on transmission of human immunodeficiency virus (

291 To understand the impact on transplant activity across the United States,

292 ed the incidence of EBV reactivation and its impact on transplantation outcomes in 71 patients underg

293 anatomy, glenoid bone loss (GBL), and their impact on treatment selection.

294 in modulating the antitumor response with an impact on tumor progression, and will have implications

295 he adaptive immune response and a modulatory impact on type I allergy is discussed.

296 s identified through this work have a direct impact on understanding and mitigating degradation in hi

297 ibed modifications of VEEV HVD have a strong impact on viral replication in vitro and pathogenesis.

298 isual impairment (VI) can have a detrimental impact on vision-related quality of life (VRQoL), but it

299 ive, and the reported AEs had no significant impact on visual acuity.

300 ge, such that frailty had a stronger adverse impact on younger patients.