ライフサイエンスコーパス: impact on

1 er investigated the reproducibility of their impact on (18)F-FDG PET quantification in patients with

2 rovide evidence that hypoxia causes economic impacts on a major fishery.

3 es in other gas and PM emissions, as well as impacts on acid and nutrient deposition, are discussed.

4 ifferentiation, rather than mitosis, have an impact on adult hippocampal volume and that these genes

5 stage-specific metabolic programs and their impact on adult neurogenesis are largely unknown.

6 ic aerosols, thus more likely to have larger impacts on aerosol radiative forcing and could serve as

7 At the opposite, the bacteria had no impact on Ag2S.

8 zation, and thus the crystal packing, has no impact on anisotropy, nor does the nature or function of

9 antibiotic allergy labels [AALs]) and their impact on antibiotic prescribing, incorporation of antib

10 l extracellular matrices, which has a direct impact on aqueous outflow resistance and IOP.

11 trial-specific physiology, atrial pathology, impact on arrhythmia occurrence, imaging, mapping, and a

12 control, the ARIA (Allergic Rhinitis and its Impact on Asthma) score ranging from 0 to 4 of the Aller

13 ea syndrome (OSAS) seems to have a favorable impact on asthma, but data are inconsistent due to metho

14 production by plasma cells and determine the impact on atherosclerotic plaque development in mice wit

15 MW imposes a negative impact on attention-based task performance, but also has

16 in multiple sclerosis (MS) to explore their impact on balance impairment in patients with MS, consid

17 of discussions on the role of water and its impact on batteries.

18 odians of the BBB in the normal brain, their impact on BBB integrity during ischemia remains unclear.

19 obally, biological invasions can have strong impacts on biodiversity as well as ecosystem functioning

20 of their interactions, exacerbating negative impacts on biodiversity.

21 ose effects may interact with climate change impacts on biota in the coming decades.

22 Bipole orientation has significant impact on bipolar EGM voltages obtained during SR and AF

23 analyzed for postoperative outcomes and the impact on blindness and visual impairment.

24 is among tremor syndromes is common, and can impact on both clinical care and research.

25 ites and the gut microbiota, with a profound impact on both host immunity and metabolic potential.

26 T availability will likely exert significant impact on both normal and pathological DAergic homeostas

27 Drought, a recurring phenomenon with major impacts on both human and natural systems, is the most w

28 sistently but, enigmatically, an anticipated impact on breast cancer survival was not observed, leadi

29 or at 2500 K (non-blue-enriched), and their impact on brightness perception, vigilant attention and

30 We examined the method's impact on calculated DPD, PH-LHD subclassification, hemo

31 drug response, which will have a significant impact on cancer precision medicine.

32 ngle delivery vehicle can have a significant impact on cancer therapy due to the potential for overco

33 ycopene content, which can have an important impact on cardiovascular disease, particularly in countr

34 loid imaging results seem to have a relevant impact on caregivers.

35 scriptome throughout life and has downstream impact on cell cycle processes.

36 anisms by which lysine methylation signaling impacts on cell fate decisions.

37 tiple proteins, can have profound biological impacts on cells.

38 and that non-AUG translation has a profound impact on cellular states.

39 l roles of NPC composition changes and their impacts on cellular processes remain unclear.

40 HBGM had no impact on child development [beta: -0.017 (95% CI: -0.13

41 ing to replication stress and minimizing its impact on chromosome instability, thus preventing diseas

42 lion cells (ipRGCs), has had a revolutionary impact on chronobiology.

43 on for human behavior is undisputed, but its impact on circadian physiology remains mostly unexplored

44 cid with immune and anabolic properties, may impact on clinical and nutritional outcomes.

45 otoxicity of fibrin(ogen), and its potential impact on clinical disability.

46 , preliminary data demonstrate a substantial impact on clinical management.

47 omposition is critical to predicting aerosol impacts on clouds and climate.

48 lution in a changing climate, and reveal the impacts on coastal areas of increasing ice mass loss and

49 sted for their pathogenicity by assaying the impact on complex formation with Ggamma and resultant mu

50 r K(+), and pharmacology, consistent with an impact on conformation of the KCNQ pore.

51 However, few studies have investigated these impacts on continental scales.

52 odels are effective means to project climate impact on crop yield, but have large uncertainty in yiel

53 l as a screening-level assessment of climate impacts on CyanoHAB prevalence as well as potential lost

54 flow intensity and pattern, with consequent impact on dand5 expression pattern and left-right (L-R)

55 PPRF may have more of an impact on decreasing antibiotic DOTs compared with PPA.

56 hese processes can therefore have a profound impact on development.

57 scalable to large channel counts with little impact on device footprint.

58 Coma Recovery Scale-Revised (CRS-R) have an impact on diagnostic accuracy of patients with disorders

59 of Arg in biological fluids has an enormous impact on disease diagnosis and in the drug development.

60 These differences need validation, and their impacts on disparities need more detailed investigation.

61 Tomography has made a radical impact on diverse fields ranging from the study of 3D at

62 n mutagenesis of FoxP3, assessing mutational impacts on DNA binding and transcriptional activation or

63 glycerol-induced kidney-injury had strongest impact on DY-654 elimination.

64 ducing macro and microscopic bile reflux and impact on dyspepsia related quality of life in long-term

65 Many exotic species have little apparent impact on ecosystem processes, whereas others have drama

66 n, growth, and competition, as well as plant impacts on ecosystem processes.

67 eda maritima) had no influence or a negative impact on elevation.

68 sure is released and could have an important impact on energy and rocketry.

69 ve opposite effects, thereby buffering their impact on enhancer activity.

70 2 decades ago, these discussions had little impact on epidemiologic practice.

71 Mutations were enriched with time, impacted on ESR1 binding to the genome and altered the E

72 Plasmodium parasitemia had no impact on EVD outcomes.

73 ology and the life sciences, with increasing impact on everyday life.

74 ntly increased CO2 production, reflecting an impact on fermentation pathways.

75 Sample weighting approaches had little impact on field-estimated trait responses to elevation.

76 virus (HIV)-infected PWUD, and assessed its impacts on first-line ART virological outcomes.

77 However, associated impacts on fisheries productivity are unclear and could

78 ment, as well as processing duration, had an impact on flaxseed protein structure since exposition of

79 rs as the only manifestation; however, their impact on FLCN function remains to be determined.

80 position are important for quantifying their impact on forest carbon (C) uptake.

81 static disease and thus might have a crucial impact on further clinical management.

82 xposure to e-cigarette aerosol had a reduced impact on gene expression compared to 3R4F smoke exposur

83 ation, reversible thiol-oxidations and their impact on gene expression in Mycobacterium smegmatis und

84 The most dramatic impact on gene expression was seen for KMO, whose activi

85 Gene copy number impacts on gene expression were detected with 528 genes

86 Its impact on glioblastoma remains largely unknown.

87 ducing deforestation has been estimated, the impact on global carbon emissions remains unquantified.

88 Southern Oscillation (ENSO) has significant impact on global climate and seasonal prediction.

89 n of ARNI With an ACE-Inhibitor to Determine Impact on Global Mortality and Morbidity in Heart Failur

90 e duration of ischemic time has the greatest impact on graft survival in recipients with older donati

91 is a 70 amino acid protein hormone, with key impact on growth, development, and lifespan.

92 uptake, VO2 max ), a trait with wide-ranging impact on health and performance indicators.

93 costs associated with the intervention, the impact on health disparities, and the acceptability and

94 ac events), use of healthcare resources, and impact on health status (quality-adjusted life-years).

95 llular models to study epigenetic mechanisms impacting on health and disease.

96 ity of social relationships have substantial impacts on health, well-being, and longevity, and, at le

97 ge-related niche changes and their suspected impact on hematopoiesis; (4) ongoing efforts to develop

98 tory (12 patients, 13%) had a nonsignificant impact on hospital mortality (odds ratio [OR], 2.1; P =

99 Stage 2-3 AKI-UO has a high negative impact on hospital mortality.

100 Asian-lineage ZIKV have different phenotypic impacts on host immune responses.

101 ial community structure can have detrimental impacts on hosts.

102 These positive impacts on housing stability and STIs highlight the impo

103 al and cytotoxicity tests showed no negative impact on human health.

104 ipally with the environment, to also include impacts on human health, culture and biodiversity conser

105 ting from changing demographics and climatic impacts on hydrology that drive nutrient transport.

106 To evaluate their impact on immune responses to sequential IAV infections,

107 he pathogenesis and severity of HF and their impact on incident HF events.

108 e, the drivers of caching behaviour, and its impacts on individuals, remain poorly understood, partic

109 still much yet to be discovered about their impact on indoor health and the unique ecological dynami

110 aediatric diarrhoea, with particularly grave impact on infants and immunocompromised individuals.

111 g in the lungs for M. tuberculosis and their impact on infection and persistence.

112 ent of surveillance data can have a dramatic impact on inferences about population processes, where t

113 le, the precise mechanism is unknown and its impact on inflammation in vivo has not been defined.

114 lows may have long-term, strategic, positive impacts on institutions.

115 idation-derived acetyl-CoA, are suggested to impact on insulin-stimulated glucose uptake.

116 conclusion, LAT1 is modulated by cholesterol impacting on its stability and transporter activity.

117 showed that gender and age have considerable impact on LA and RA size and function.

118 are the preferred option, even though their impact on leukemic transformation and survival has not b

119 offers hope in mitigating their catastrophic impact on life, agriculture and property.Against the bac

120 and antioxidant activity whereas a negative impact on lipase inhibitory activity was observed (p<.00

121 ng in notable ecosystem consequences through impacts on litter decomposition and further biogeochemic

122 Greatest impact on liver function was found in animals with polym

123 designed to assess whether resistance had an impact on LLINs.

124 tomy (RPD) is gaining momentum; however, its impact on major outcomes, including pancreatic fistula,

125 Thus, young genes have a preferential impact on male reproductive system function.

126 rsing fluid chemistry could have significant impact on material survivability.

127 about placental vitamin D metabolism and its impact on maternal circulating vitamin D concentrations

128 is is concerning as in addition to immediate impacts on maternal wellbeing, obesity during pregnancy

129 as local investigation of tablet and capsule impact on medication administration errors and staff tra

130 -FHbp and MenB-4C do not have a large, rapid impact on meningococcal carriage and are unlikely to pro

131 g therapeutic antibiotics, has a significant impact on microbial population structures and their gene

132 The DYT4 mutation had no impact on microtubule dynamics suggesting a distinct mec

133 However, their biological function and impact on miRNA networks are unclear.

134 er negative outcomes, but its prevalence and impact on modern multimodal regimens for LAEC have not b

135 c gene expression but did not have long term impact on monocyte identity regarding their differentiat

136 irin has been used, but case studies show no impact on mortality rates.

137 ion of altered met abolic pathways and their impact on motor neuron survival.

138 e regulation of IL7R exon 6 splicing and its impact on MS risk.

139 ET bromodomains, which resulted in a minimal impact on MYC transcription, but did not result in a sta

140 need for lead time and consideration of the impact on national policies should be considered.

141 lata is a common invasive shrub, and similar impacts on native species might occur in its invasive ra

142 ociated with the active compound, ecological impacts on natural environment, and insufficient investm

143 Nov 13, 2017, I describe the scale of human impacts on natural systems and the extensive associated

144 thod can be used to simultaneously probe the impact on neural encoding of natural stimulus variabilit

145 ctrin, followed by NaV channels, with modest impact on neurofascin 186.

146 A Phase III randomized trial to assess impact on neurologic outcome of intracranial pressure pl

147 sing ancient nuclear DNA [1, 2], its genetic impact on northern and eastern parts of this continent h

148 cancer (LAEC), and to assess its independent impact on operative and oncologic outcomes.

149 solate rapidly growing cells and limit their impact on organ shape.

150 ations of HR-related genes have a phenotypic impact on other cancers remains to be fully elucidated.

151 Their respective prognostic impacts on outcome prediction were compared using receiv

152 e objective of this study was to analyze the impact on overall survival (OS) from the addition of pos

153 Associated impacts on overall community structure are, however, les

154 d whether and how memory reactivation has an impact on overlapping memories acquired during awake tim

155 on of a common lncRNA target with downstream impact on paraspeckle morphology and function.

156 Online TMS over rTPJ also impacted on participants' explicit beliefs, causing them

157 ssessments outside of tertiary care centers, impacts on partners and families of adult patients, and

158 host response to enteric pathogens, but its impact on pathogenesis remains poorly defined.

159 not agree in their conclusions regarding its impact on pathogenesis.

160 h can reduce nurses' autonomy and negatively impact on patient care.

161 e-sponsored study of ID physicians' positive impact on patient outcomes shows that few medical specia

162 Chronic rhinosinusitis has a significant impact on patient quality of life, creates billions of d

163 The impact on patient survival of an infectious disease (ID)

164 nder researched and little is known of their impact on patients' lives.

165 d and relapsed peritoneal metastasis and its impact on patients' outcomes.

166 k, expertise and efficacy, and the long-term impact on patients' survival.

167 II area under the curve, AUROC2), but had no impact on perceptual decision making performance.

168 We then applied this assay to test the impact on peritoneal immune-competence of PD fluid suppl

169 HP small molecules could have a dramatic impact on persistent, biofilm-associated bacterial infec

170 ines was found to correlate directly with an impact on Pgp-derived efflux.

171 use below-average temperatures had a greater impact on phenology than above-average temperatures, the

172 wed lower growth and seed production with no impact on photosynthesis.

173 and thus the choice of loci can have a major impact on phylogenetic reconstruction.

174 crease enzyme accessibility without negative impacts on plant growth or cell wall composition.

175 ol in synthetic polymers can have a dramatic impact on polymer properties and self-assembly.

176 However, survival, which has a greater impact on population growth, was little affected by clim

177 reach immunization sessions might reduce its impact on population immunity.

178 obese or overweight have not had sufficient impact on pregnancy and birth outcomes, which suggests t

179 ultrasound-based pregnancy dating to assess impacts on preterm birth and fetal growth in all studies

180 onal-salient cues could exert a differential impact on proactive (the restrain of actions in preparat

181 2 missense SZ-risk mutation had a pathogenic impact on projection neuron laminar allocation by reduci

182 The resulting data allow us to quantify the impact on protein expression of Kozak sequence compositi

183 eased protein stability, suggesting a likely impact on protein function.

184 Computational prediction of mutation impacts on protein stability offers a fast, economical a

185 sure is critical to mitigating its potential impact on public health.

186 Aggregates of viruses can have a significant impact on quantification and behavior of viruses in the

187 and use a model to demonstrate the resulting impacts on regional air quality.

188 ons can reduce host fitness through negative impacts on reproduction and survival, even if they produ

189 Our findings have a significant impact on research related to MPYS-mediated human diseas

190 While environmental impacts on resistance have been extensively, recorded th

191 Somatic mutations such as CARD11 may have an impact on response to ibrutinib, may inform clinical dec

192 trong risk factor) and 5-HTTLPR genotype (no impact on risk) are strikingly consistent across our con

193 parts subtle if any structural or functional impact on RNAP in the absence of RIF.

194 ay radiation have great potential for a wide impact on science, and are a critical element for unrave

195 cation and has a significant epidemiological impact on seasonal and pandemic influenza.

196 arsenate sorption capacity but had a strong impact on selenate uptake, suggesting some kind of speci

197 ure to be feasible but surgical outcomes and impact on short and long-term morbidity rates are yet to

198 important implications in understanding its impact on skin homeostasis and pathogenesis.

199 Pacific subtropical highs (PSHs) have major impacts on social and ecological systems.

200 d for an improved understanding of biochar's impacts on soil NO emissions.

201 panying global warming and may have profound impacts on soil respiration (Rs) and its components, tha

202 s in antibody CDRs display context-dependent impacts on specificity and that affinity/specificity tra

203 teraction can be achieved; this has a direct impact on spectroscopic methods such as Raman scattering

204 sis of (68)Ga-PSMA-11 PET/CT implied a major impact on SRT planning in 52 of 270 patients (19%) with

205 r with radioligands might have a significant impact on staging and treatment of GRPR-expressing tumor

206 nt-associated activity has a strong negative impact on stem/progenitor cell preservation in limbal ex

207 anagement actions to mitigate climate change impacts on stream ecosystems or to proactively adapt to

208 th metastatic NET (4 papers, yield was 44%); impact on subsequent NET patient management (4 papers, c

209 n of natural sounds produced when one's body impacts on surfaces have recently been evidenced.

210 adjust to a new steady-state level, with an impact on surrounding brain cells, remains unknown.

211 t the mechanisms governing this flow and its impact on symbiosis remain poorly understood.

212 increase tumor immunogenicity, the negative impact on T-cell activity is functionally important.

213 idespread phenomenon that has had a profound impact on TE dynamics and, consequently, on the evolutio

214 iwi2-expressing cells results in a transient impact on testicular homeostasis, with this population b

215 f diabetes, HbA1c, BMI, BCVA, and CST had no impact on the ability to achieve >/=2-step improvement i

216 lution of climate data will have the largest impact on the accuracy of biological predictions under c

217 Stratocumulus clouds (Sc) have a significant impact on the amount of sunlight reflected back to space

218 In addition, the potential impact on the brain should be considered with regards to

219 ies of GNRs, the edge structure has a strong impact on the carrier mobility in GNRs by affecting the

220 been described, less evidence exists on the impact on the cerebellum.

221 ed to the bulge site, thereby having minimal impact on the cleavage site.

222 TION: The number of CRS-R assessments has an impact on the clinical diagnosis of patients with chroni

223 ns differ in their composition, which has an impact on the clinical presentation and the underlying d

224 ansfer RNA available for protein translation impact on the configuration of epithelial mesenchymal tr

225 ivity of autophagy pathways as well as their impact on the development of human diseases.

226 his variation between results and its likely impact on the enforcement of the EU gluten-free legislat

227 rug interventions can extend lifespan, their impact on the epigenome is uncharacterised.

228 Although little impact on the forward (dark- to light-adapted form) phot

229 While IVM had no major impact on the functions of dendritic cells in vivo and i

230 methylates regions of interest with minimal impact on the global DNA methylome and transcriptome.

231 Diabetes has a significant impact on the gut microbiota; however, studies in the or

232 hospitalised cases of pneumonia and a marked impact on the incidence of severe childhood pneumonia.

233 These findings have a direct impact on the interpretation of (68)Ga-DOTATATE PET/CT s

234 man disease; (2) experimental design and its impact on the interpretation of data; and (3) standard m

235 , the extruder die did not have a measurable impact on the molecular weight reduction of waxy flour.

236 on of Hif1a, Epas1, or both together, had no impact on the number of myeloid cells migrating into the

237 oducing a bias toward GDP tubulin has little impact on the observed MT stabilization.

238 antity of meibum is altered, with a negative impact on the ocular surface.

239 ence of the ballasts has a slightly negative impact on the open circuit voltage.

240 terface and interaction should have profound impact on the optimization and de novo design of new NM

241 mmune system represent prime candidates that impact on the pathogenesis of immune-mediated diseases a

242 eristics examined had a minimal impact or no impact on the payment differential.

243 iated materials have a local and/or systemic impact on the peri-implant soft and hard tissues.

244 e report that treatment efficacy has a clear impact on the population dynamics: sufficient drug press

245 gest that the vaccination program has had an impact on the prevalence of HPV types 6, 11, 16, and 18

246 s-tags are generally assumed to have minimal impact on the properties of the fusion protein, as they

247 re solution and refinement, and has a strong impact on the quality of electron-density maps.

248 oblem, due to its prevalence, morbidity, and impact on the quality of life.

249 ze treatment strategies to reduce a negative impact on the quality of survivorship.

250 al effects and does not have any significant impact on the reactivity at positions [Formula: see text

251 t the 2009 influenza pandemic has an evident impact on the relative burden of the two influenza types

252 ion selected for the addition had a definite impact on the results.

253 urine and myo-[(3) H]inositol, without major impact on the simultaneously measured efflux of the char

254 ing or pars plana vitrectomy seem to have no impact on the success of the toric IOL implantation, eve

255 ents with metastatic prostate cancer and its impact on the therapeutic response as determined by pros

256 higher lactate dehydrogenase had a negative impact on the therapeutic response; however, the multiva

257 tatively propagated autotetraploid and their impact on the transcriptome.

258 eubiquitinating enzyme, Usp9x, and has major impact on the tumorigenic program of metastatic melanoma

259 FASTA format and can be further analyzed for impact on the underlying protein structure.

260 onditions this diazotroph has a considerable impact on the wider carbon cycle.

261 to be detrimental at breeding colonies, but impacts on the annual survival of pelagic adults and juv

262 mical changes associated with cell death and impacts on the cell cycle in three dinoflagellate specie

263 can have detrimental, costly or irreversible impacts on the environment and society.

264 ymer wastes and their associated detrimental impacts on the environment, the plastic life cycle has d

265 ess is often tacitly assumed to reduce human impacts on the environment.

266 Our findings suggest therefore that human impacts on the global mercury cycle are subtler and subs

267 nges in climate, which will have substantial impacts on the livelihoods of the more than 180 million

268 ing expanded nursing roles and task shifting impacts on the morale, retention, and professional devel

269 budgets developed to quantify anthropogenic impacts on the nitrogen cycle do not explicitly consider

270 okes the release of serotonin, which in turn impacts on the serotonin 1A receptor system, by modulati

271 y-storage dielectrics will have far-reaching impacts on the sustainable energy and will be an importa

272 Fab' fragments within the lungs had a major impact on their residence time, with the deeper the deli

273 ng binocular vision [1, 2], and experience's impact on this neural balancing act continues into adult

274 R, 2.6; P = .003) had independent prognostic impact on time to relapse.

275 essential enhancer-protein complexes with an impact on timely gene activation.

276 and composition of the films, but negligible impact on TiOx surface silanization effectiveness.

277 By contrast, E2F3 repression has minimal impact on tissue proliferation or homeostasis in the maj

278 th evolution and disease, yet its functional impact on transcription factor (TF) occupancy and enhanc

279 ction with specific targets, and thus has an impact on transcription regulation.

280 n complexity but little is known about their impact on translation.

281 may improve both vaccine feasibility and the impact on transmission.

282 Vs were considered to have a potential major impact on treatment planning.

283 nical indications, diagnostic potential, and impact on treatment planning.

284 d large-scale droughts had a strong negative impact on trembling aspen growth.

285 Significant human impacts on tropical forests have been considered the pre

286 Hypoxic stress has a strong impact on tumor cell biology.

287 can help elucidate developing ELNs and their impact on tumor progression.

288 The impact on U(VI) adsorbed to lepidocrocite (gamma-FeOOH)

289 V71-host cell interactions and has potential impact on understanding other enterovirus-host cell inte

290 g-term ecological drivers can have cascading impacts on understanding higher order ecological phenome

291 stance have been extensively, recorded their impacts on variation in tolerance are virtually unexplor

292 an important role in lipid homeostasis, with impact on various metabolic diseases.

293 plete, as silencing of PKR expression has no impact on viral propagation.

294 itic cells in the draining lymph node had no impact on viral replication in this organ, suggesting th

295 te SG formation, suggesting that SGs have an impact on virus infection.

296 working distances (far, 60 cm and 33 cm) and impact on vision quality of multifocal IOLs AcrySof ResT

297 udies of peripheral changes in AMD and their impact on visual function may contribute to understandin

298 r Bdnf in this brain region does not have an impact on weight, activity levels, anxiety, or depressio

299 stability of the wines without a significant impact on wine colour.

300 For occludin, down-regulation had no impact on wound healing in normal scratch assays, but af