ライフサイエンスコーパス: impaired

1 ormally present in wounds, wound healing was impaired.

2 bone morphogenetic protein (BMP) signals are impaired.

3 dour-induced attractive social responses are impaired.

4 apoA-IV gene expression and food intake are impaired.

5 resence is attenuated and mating behavior is impaired.

6 during hospitalization, and 11% (n=174) were impaired 1 month after discharge.

7 activation of DNA damage response (DDR) and impaired ability to differentiate into myotubes.

8 Deficits in the salience network suggest an impaired ability to process physiologically salient even

9 I (Gly119Arg and Leu131Arg) variants have an impaired ability to regulate complement activation and m

10 terations in cognitive processes known to be impaired across psychiatric conditions.

11 misshapen and nucleated erythrocytes, due to impaired actin assembly and cytoskeleton stability.

12 molecules, disrupted glutamate homoeostasis, impaired action of antipsychotics, and development of an

13 w enhancers in embryonic stem cells leads to impaired activation of HoxA genes upon differentiation,

14 Thus, impaired adaptation in cortical sensory circuits is a po

15 NADH production rate remained significantly impaired after 10 min of reperfusion after global ischem

16 These aspects of daily life are known to be impaired after extended wake, yet, the underlying neuron

17 on in maximal GABA-evoked Popen , suggesting impaired agonist efficacy.

18 Moreover, impaired AJ activity can account for the endothelial dil

19 Furthermore, the impaired alcohol seeking was associated with structural

20 nificant difference was observed between the impaired and nonimpaired groups in the association of fr

21 he sympathetic skin response of the foot was impaired and sweat gland innervation was reduced.

22 tion of sorted LPS-stimulated MZ B cells was impaired, and aged bumble mice were unable to respond to

23 (EMT), as well as enhanced fibrinolysis and impaired angiogenesis.

24 nsmission in medial prefrontal cortex (mPFC) impaired appetitive trace conditioning at a 2 s trace in

25 h genetic and physiologic evidence points to impaired arousal responses to hypercarbia and hypoxia, w

26 Moreover, whether such dynamic coupling is impaired as a consequence of brain aging in later life,

27 displayed intact cochlear amplification but impaired auditory brainstem responses.

28 ce, activation of PI3 kinase-mTOR signaling, impaired autophagy, mitochondrial dysfunction, stem cell

29 found increased anxiety-related behavior and impaired aversive learning as well as markedly affected

30 alization of these proinflammatory cytokines impaired bacterial clearance and eliminated host protect

31 immense hope to individuals who are visually impaired because of RPE65 mutations.

32 stasis, including lack of recovery sleep and impaired behavioral adjustment to a novel task after sle

33 sponses in the MD system were accompanied by impaired behavioral performance.

34 d S1450F in rodents, respectively) displayed impaired binding to membrane-associated guanylate kinase

35 ignals in developing visual cortex can cause impaired binocular vision and amblyopia.

36 levated blood viscosity, which contribute to impaired blood flow and other pathophysiological aspects

37 e with knockout of SREBP2 in astrocytes have impaired brain development and behavioral and motor defe

38 WM development are a major factor underlying impaired brain growth and microcephaly in the disorder.

39 eir ligands Fgfs Deleting Fgfr1/2/3 not only impaired bSC dendritogenesis but also abolished glutamat

40 The same parameters were impaired by a similar CSC concentration in vivo Finally,

41 e inhibitor, restored performance in animals impaired by continuous stimulation but did not improve p

42 the catalytic activity of the enzyme was not impaired by exposure to radiation during the pulse radio

43 ing was increased by Gab2 overexpression and impaired by Gab2 deletion via regulation of Jak2 and sig

44 o to investigate single molecule dynamics is impaired by the absence of an efficient way to chemicall

45 ng showed that both targets are functionally impaired by the beta-lactone.

46 coupled import-integration reaction that was impaired by the SECA inhibitor sodium azide.

47 d a mechanism-based SCF partial agonist that impaired c-Kit dimerization, truncating downstream signa

48 fish ncx1 mutant, we explored the impacts of impaired Ca(2+) homeostasis on myofibril integrity.

49 ay of symptomatic characteristics, including impaired Ca(2+) transients, upregulation of Na(+)/Ca(2+)

50 yed diacylglycerol clearance from the PM and impaired Ca(2+)-triggered phosphatidylserine scrambling.

51 uses developmental cardiac abnormalities and impaired cardiovascular function.

52 TRAIL-R suppression in tumor cells impaired CCL2 production and diminished both lung MDSC p

53 larization toward a regulatory phenotype and impaired CD8(+) T cell allo-reactive responses, includin

54 -mediated membrane trafficking, resulting in impaired cell adhesion and migration in vitro.

55 Moreover, CDK20-depleted cells display impaired cell proliferation, defective G2/M arrest and i

56 Impaired CFR was similarly present among women and men,

57 C4 synthase-deficient eosinophils exhibited impaired chemotaxis to CCL19 that was restored by exogen

58 tic mechanisms involved in CF, which include impaired chloride permeability and persistent lung infla

59 of macrophage-like SMCs in the lesions, and impaired cholesterol efflux.

60 deficits lead to poor functional outcome via impaired cognition and increased negative symptoms.

61 neurodevelopmental condition associated with impaired cognitive and adaptive behaviors.

62 children <5 y of age and is associated with impaired cognitive and motor development and increased m

63 Genetic ablation of Zbtb7b impaired cold-induced transcriptional remodeling in brow

64 adrenal steroidogenesis pathway that lead to impaired cortisol biosynthesis.

65 DCs from these mice show impaired cross-presentation ex vivo and defective cross-

66 PET revealed impaired CVRC in 8 patients (44%).

67 of reduced CXCL12 scavenging by mutants with impaired CXCL12 affinity required drastically reduced re

68 ive neural tube defects (NTDs) indicate that impaired de novo thymidylate (dTMP) synthesis through ch

69 Impaired delivery of antifungals to hyphae within necrot

70 Jarid2-deficient pancreases exhibit impaired deposition of RNAPII-Ser5P, the initiating form

71 and low birth weight have been implicated in impaired development of the retina.

72 This impaired DI splicing affects proliferation genes, whose

73 The impaired diabetic BMPC angiogenic function was rescued b

74 M) is a rare cardiomyopathy characterized by impaired diastolic ventricular function resulting in a p

75 Surprisingly, reduced GATA1 expression and impaired differentiation were limited to megakaryocytes,

76 Additionally, with the impaired dilator responses, a modest increase in adrener

77 e imaging (MRI) is hypothesized to represent impaired drainage of interstitial fluid from the brain a

78 erimental data suggest that efferocytosis is impaired during atherogenesis caused by dysregulation of

79 62+/-11 years; 16% (n=237) were cognitively impaired during hospitalization, and 11% (n=174) were im

80 This finding was associated with an impaired early vascularization and stromal tissue growth

81 , ECD mRNA levels were increased, suggesting impaired ECD translation as the mechanism for reduced pr

82 ed in a halt of cell proliferation, severely impaired EGFR signaling and the onset of cellular senesc

83 Biochemically mutant mice showed impaired electron transport chain activity and accumulat

84 al compartments, respectively, supporting an impaired endocytic lipid antigen presentation for T cell

85 anoparticle-positive areas further exhibited impaired endothelial barrier function as illuminated by

86 results in decreased glycolysis, leading to impaired endothelial cell proliferation and migration.

87 reased local TNF-alpha levels, might lead to impaired eosinophil resolution and could contribute to t

88 Both patients and murine models revealed an impaired epidermal structure, ascribed to aberrant secre

89 Furthermore, we found that a PKA inhibitor impaired ES cell proliferation, tumor growth and metasta

90 educed protection in infancy could be due to impaired establishment of lung TRM.

91 ot affect synapse numbers but differentially impaired excitatory or inhibitory synaptic functions in

92 in secondary MR, however, is associated with impaired exercise capacity and increased mortality.

93 Transcriptome analysis revealed impaired expression and splicing of genes with essential

94 ategorically specific, as inactivation of ML impaired face detection while sparing body and object de

95 fulfilled the inclusion criteria (NAFLD with impaired fasting glucose or impaired glucose tolerance)

96 y of elderly women in Denmark, we found that impaired fasting plasma glucose concentration was associ

97 rain had multiple phenotypes associated with impaired Fe-S protein maturation.

98 sion of meristem/tissue identity markers are impaired from the "symmetry-breaking" periclinal cell di

99 sive-compulsive disorder (OCD) are caused by impaired frontostriatal function.

100 thromboxane A2 production may contribute to impaired functional dilator and hyperaemic responses at

101 Secondary outcomes were impaired functioning (measured by the WHO Disability Adj

102 CHK2 activation in response to irradiation, impaired G2 checkpoint proficiency and radiosensitizatio

103 ognition, because mutations at this position impaired GEF-mediated nucleotide exchange.

104 by fungal and bacterial infections caused by impaired generation of TH17 cells; meanwhile, some patie

105 In alphaRaptorKO mice, impaired glucagon secretion occurred in response to diff

106 In conclusion, SGLT2-I treatment improves impaired glucose effectiveness in the liver and insulin

107 n resultant obesity-related hypertension and impaired glucose intolerance.

108 n of TBK-1 in mice with diet-induced obesity impaired glucose metabolism and AKT activation.

109 sformed and categorized into quartiles) with impaired glucose tolerance (IGT) and gestational diabete

110 -IR]) in a large group of subjects with NGT, impaired glucose tolerance (IGT), and T2DM.

111 lucagon levels are observed in subjects with impaired glucose tolerance (IGT).

112 th control littermates, knockout mice showed impaired glucose tolerance and circulating leptin, GLP-1

113 edentary dams produced female offspring with impaired glucose tolerance compared with offspring of ch

114 ese patients with coronary heart disease and impaired glucose tolerance were randomly assigned (1:1),

115 , HbA1c [-10 g/L (95% CI: -12.90, -7.10 g/L; impaired glucose tolerance) and -6 g/L (95% CI: -8.47, -

116 eria (NAFLD with impaired fasting glucose or impaired glucose tolerance) and were randomly assigned i

117 ese patients with coronary heart disease and impaired glucose tolerance, acarbose did not reduce the

118 mice, resulted in decreased beta cell mass, impaired glucose tolerance, defective insulin secretion,

119 autoantibody-positive at-risk children with impaired glucose tolerance.

120 selective deletion of StarD10 in mice led to impaired glucose-stimulated Ca(2+) dynamics and insulin

121 (-/-) mice, oxidative stress associated with impaired glutathione synthesis and nuclear factor erythr

122 he context of neuronal diseases caused by an impaired glyoxalase system and elevated levels of dicarb

123 A mot1.3-1 knockout mutant showed impaired growth concomitant with a reduction of nitrogen

124 apoptosis in hypoxic cancer cells as well as impaired growth of tumor xenografts.

125 Overexpressing PEX1 in wild-type plants impaired growth, suggesting that excessive PEX1 can be d

126 tive HNSCCs and suggest a potential role for impaired H3K36 methylation in their development.

127 process and deficiencies in the MMP9 lead to impaired healing.

128 odel that exhibits heat-shock (HS) inducible impaired heart regeneration.

129 ss using Zip14(-/-) (KO) mice, which exhibit impaired hepatic zinc uptake.

130 A2/3) and CA4/dentate gyrus (DG), as well as impaired hippocampal microstructural integrity.

131 We found that tau deletion leads to an impaired hippocampal response to insulin, caused by alte

132 PD-1 identifies "exhausted" CD8 T cells with impaired HIV-specific effector functions, but its role o

133 d reduced pSTAT4, nuclear translocation, and impaired IFN-gamma production.

134 AT1R knockdown impaired IL-1beta-induced IL-6 and IL-8 secretion in cul

135 factors, environmental toxins and stressors, impaired immune responses, mitochondrial dysfunction, an

136 regs in vivo at the start or stop of therapy impaired immune tolerance, highlighting the dependence o

137 IL-33 dysregulated lung Treg cells and impaired immunologic tolerance to inhaled antigens.

138 associated RH domain-interacting protein was impaired in a male fetus with IP, leading to defective l

139 acking SPN, SLO, and both toxins are equally impaired in ability to cause necrotizing myositis.

140 nity between Sesn2 and AMPK upstream LKB1 is impaired in aged hearts during ischemia (P < 0.05 vs. yo

141 R-mediated canonical NF-kappaB signaling was impaired in all mature naive CVID-derived B cells.

142 on fork stalling, as replication-restart was impaired in both SMI#9-pretreated and RAD6B-silenced cel

143 binding of the UBXD1 adaptor protein that is impaired in disease; this underlies the potential for re

144 formation of NEMO-containing structures was impaired in fibroblasts from patients with IP carrying t

145 berculosis-specific CD4 T cells was markedly impaired in HIV-infected individuals, compared with HIV-

146 ins full metabolic activity, but is 100-fold impaired in its ability to activate APJ.

147 ils and inflammatory cytokine production are impaired in M-ILK-deficient mice, and activation of epit

148 cose uptake and hypertrophic growth were not impaired in muscle-specific GLUT4 knockout mice, demonst

149 Everyday visual search can be impaired in patients with common eye diseases like glauc

150 ood mononuclear cells was also significantly impaired in RRMS.

151 evelopmental plasticity and connectivity are impaired in sensory systems in DS model mice, that such

152 o the CD4(+)CD8(-) single-positive stage are impaired in Themis(-/-) mice, suggesting that Themis mig

153 T)-associated protein of the EMAP family, is impaired in these mice.

154 pro-apoptotic mediators CamkII and Stat1 was impaired in Trpc3-deficient M1 cells, gathering insight

155 Cell phagocytosis is impaired in type 2 diabetes and requires RvE1 for activa

156 ed that a Xanthomonas strain lacking raxX is impaired in virulence.

157 causes infertility due to meiotic arrest and impaired inactivation of sex chromosomes.

158 Phage-resistant mutants had impaired infectivity.

159 rosclerotic lesion that displays features of impaired inflammation resolution, notably a necrotic cor

160 er-associated rare variant (M2145T) in TGEF2 impaired inhibition by the TGEF2 pleckstrin-homology dom

161 Impaired inhibition of fear or behavioral responses is t

162 se the possibility that septic patients have impaired insulin clearance, which could increase their s

163 A hallmark of type 2 diabetes is impaired insulin receptor (IR) signaling that results in

164 ucible ablation of LDB1 in mature beta cells impaired insulin secretion and glucose homeostasis.

165 tivity display decreased insulin content and impaired insulin secretion.

166 by trapping it in the endosomes, leading to impaired insulin signaling and insulin-stimulated mitoch

167 Impaired insulin/insulin-like growth factor-1 signalling

168 Impaired integrin activation on neutrophils is the hallm

169 We investigated whether impaired intestinal permeability contributes to these sy

170 s from MetSyn or LPS-injected rats exhibited impaired intrinsic contractile activity and associated i

171 t is similar to wild-type aged hearts (i.e., impaired ischemic AMPK activation and higher sensitivity

172 ethyloxalylglycine (DMOG) also significantly impaired iTreg differentiation.

173 C903-induced expression of TSLP and reverses impaired keratinocyte differentiation.

174 rome of Lowe (OCRL) and share the feature of impaired kidney proximal tubule function.

175 its absence, secretory vesicle formation is impaired, leading to accumulation of immature vesicles,

176 ed that recycling of the TCR-CD3 complex was impaired, leading to increased lysosomal targeting and r

177 related behavior, hyperhedonia, hyperphagia, impaired learning and memory and exaggerated startle res

178 apoptosis, altered DG cell composition, and impaired learning and memory.

179 However, PPM is associated with impaired left ventricular ejection fraction recovery pos

180 etriotic lesions, which may contribute to an impaired lesion vascularization and growth.

181 y (LAD) syndrome in humans, characterized by impaired leukocyte recruitment and recurrent infections.

182 n ZFP36L1-deficient mice were accompanied by impaired lipid absorption that was consistent with alter

183 gatroban is contraindicated in patients with impaired liver function, and activated partial thrombopl

184 xplore the role of natural killer T cells in impaired liver regeneration.

185 Both transiently impaired locomotion through an off-target effect that di

186 Acute consumption (1.34 ng/bee) impaired locomotion, caused hyperactivity (velocity: +10

187 restricted trafficking of CAR T cells to and impaired long-term persistence at the tumor site, as wel

188 nfants are predisposed to illness because of impaired lung function or whether respiratory illness re

189 essive sIgE production and directly affected impaired lung function.

190 through multiple mechanisms, one of which is impaired lysosomal proteolytic activity.

191 Ablation of Gnb5 impaired M3R-stimulated phosphorylation of ERK1/2.

192 Surprisingly, we found that jet lag impaired major parameters of home-team offensive perform

193 These associations may reflect impaired maturation of intestinal immunity and integrity

194 est that ribosomal deficiency contributes to impaired megakaryopoiesis in myeloproliferative neoplasm

195 Impaired mitochondria and accumulated H2O2 production re

196 effect), extensive glutamine utilization and impaired mitochondrial electron flow.

197 e population of processing intermediates and impaired mitochondrial function.

198 nts with sporadic late-onset AD suggest that impaired mitophagy contributes to synaptic dysfunction a

199 he mitophagy mediators BNIP3 and BNIP3L, and impaired mitophagy.

200 ith excessive manganese accumulation was the impaired motor function observed in the Zip14 KO mice.

201 : +44%) shortly after exposure (30 min), and impaired motor functions (falls: +83%; time top: -43%; t

202 t data, rendering clinical interpretation of impaired movement patterns sub-optimal.

203 e marrow adiposity, decreased bone mass, and impaired MSC self-renewal capacity in mice.

204 Further, mutant PKCepsilon caused impaired mTORC2-dependent pAKT-S473 following rapamycin

205 allergy development, possibly indicating an impaired mucosal barrier function in allergic children.

206 We sought to determine the role of impaired mucus clearance in the pathogenesis of allergen

207 genetic variants act through a mechanism of impaired muscle cell differentiation and tissue formatio

208 rmal spectra of basic behavioral activities, impaired muscle grip strength, and defects in motor coor

209 tion with Cobra Venom Factor (CVF) result in impaired muscle regeneration following cardiotoxin-induc

210 Moreover, loss of SEP4 severely impaired mutant conidiation, melanin and chitin accumula

211 ption of Myc function or sterol biosynthesis impaired myeloid differentiation.

212 m levels in HFpEF are neither a result of an impaired Na(+) gradient nor expression changes in key io

213 ses a spectrum of brain malformations due to impaired neuronal migration in the developing cerebral c

214 subjects, causing hemolytic anemia linked to impaired nicotinamide adenine dinucleotide phosphate (NA

215 ereas lineage-negative progenitors displayed impaired NK-cell differentiation.

216 vel, severe form of leukodystrophy caused by impaired NKX6-2 function.

217 mitant with reduced NMDA-evoked currents and impaired NMDAR-dependent insertion of GluA1 at stimulate

218 OS dysfunction, as indicated by the level of impaired O2 extraction from arterial blood during peak e

219 Mutants lacking TAG or impaired of TAG hydrolysis show spore wall assembly defe

220 ary cells revealed one substitution severely impaired OGFOD1-dependent hydroxylation of a neighboring

221 rated that senescent-cell conditioned medium impaired osteoblast mineralization and enhanced osteocla

222 rovascular obstruction during a VOC leads to impaired oxygen supply to the periphery and ischemia rep

223 =80-year-old subjects with CNV were visually impaired (P = 0.016).

224 earch has linked age-related hearing loss to impaired performance across cognitive domains and increa

225 Se doses (32.5 and 57.5 mug Se/g) exhibited impaired performance in the latent learning task.

226 by the Confocal Leak Score (CLS; range: 0=no impaired permeability to 100=complete loss of barrier fu

227 2-expressing macrophages were accompanied by impaired phosphorylation of IL-1R-associated kinase 1 (I

228 aves of polyprenol-deficient plants revealed impaired photosystem II operating efficiency, and their

229 r people face a high risk of muscle loss and impaired physical function, which may contribute to sarc

230 ing per se without the confounding impact of impaired physical function.

231 naling or cathepsin B function significantly impaired PNI in vivo Correlative studies in human specim

232 Depletion of satellite cells impaired post-burn recovery of both muscle fibre cross-s

233 Schizophrenia has been associated with impaired predictive processing, but the underlying mecha

234 " crossed the fixed threshold from intact to impaired pressure reactivity (pressure reactivity index

235 torial injury are important risk factors for impaired preterm cerebellar biochemistry.

236 The presence of Retro94 results in severely impaired production of infectious virions, with a decrea

237 icating a possible mechanism contributing to impaired proliferative capacity of M. tuberculosis-speci

238 We observed reduced myotube diameter, impaired protein synthesis, and increased autophagy flux

239 of repeated systemic sting reactions and/or impaired quality of life.

240 Impaired rate-dependent depression (RDD) of the Hoffman

241 Impaired RDD and allodynia were present in type 1 and ty

242 We have investigated the pathogenesis of impaired RDD in diabetic rodents exhibiting features of

243 riate expression of MMP9 also contributes to impaired re-epithelialization.

244 pro-inflammatory activation of macrophages, impaired recruitment and activation of peritoneal fibrob

245 inment in MARCO(-/-) mice was accompanied by impaired recruitment of Ly6C(high) monocytes and monocyt

246 d that the phosphorylation of PTPN12 by CDK2 impaired recruitment of the serine/threonine-protein kin

247 Lgr5(Creert2)/Met(fl/fl)/LacZ mice had impaired regeneration of MET-deficient ISCs.

248 ion fork stalling, chromosome fragility, and impaired repair.

249 tive efferocytosis and its possible links to impaired resolution in atherosclerosis are incompletely

250 The impaired response propagation from the stimulation site

251 with unrestrained fibroblast proliferation, impaired scar remodeling, reduced fibroblast-derived col

252 Impaired signaling via CX3CR1, the fractalkine receptor,

253 paired spatial tuning of neural activity and impaired sparse coding of information, and deficits in t

254 lope of the "inverted-U" input-output curve, impaired spatial tuning of neural activity and impaired

255 assium chloride cotransporter expression and impaired spinal gamma-aminobutyric acid type A receptor

256 Importantly, AZD4547 impaired stem cell-like characteristics in primary MECs

257 to the DeltaICP0 HSV-1 is in part due to an impaired STING pathway.IMPORTANCE The DNA sensor STING p

258 This dimeric ERdj3 shows impaired substrate binding both in the ER and extracellu

259 In turn, this impaired SUFU-mediated repression of the SHH pathway, as

260 The effect of an impaired sweet-taste perception system on cognition func

261 elated and non-combat related mental stress, impaired sympathetic and cardiovagal baroreflex sensitiv

262 atric disorders including cognitive decline, impaired synaptic plasticity, reduced sociability, hyper

263 ficiency (SCID) is characterized by severely impaired T-cell development and is fatal without treatme

264 rneurons, even transiently during the delay, impaired task performance, primarily by increasing inapp

265 ndogenous alpha-band networks, which in turn impaired task performance.

266 the organ of Corti and the vestibular organ, impaired terminal differentiation manifests as immature

267 n in the Pnpla3(148M/M) mice being caused by impaired TG mobilization from LDs.

268 Serotonin depletion impaired the ability of exendin-4, a clinically used GLP

269 Finally, whole OSPW also impaired the ability of RAW 264.7 cells to perform phago

270 ir spatial learning or retrieval per se, but impaired the ability to follow changing spatial rules.

271 Gi-DREADDs in the basolateral amygdala (BLA) impaired the acquisition of both conditioned fear extinc

272 Conditional deletion of T-bet from B cells impaired the formation of germinal centers and mitigated

273 The absence of functional PNPLA1 in mice impaired the formation of omega-O-acylceramides and led

274 Mutations in ARTEMIS-deficient patients impaired the interaction with the C terminus and also af

275 Hyperglycemia and hyperinsulinemia also impaired the PI3K/Akt while enhancing the ERK/p38MAPK/JN

276 netic ablation of sensors of apoptotic cells impaired the proliferation of tissue-resident macrophage

277 us LGI4 transcript and in a cell-based assay impaired the secretion of truncated LGI4 protein.

278 However, despite conscious access being impaired, the ability to decode the presence of integrat

279 xtensive long-term culture-induced MSC aging impaired their osteogenic ability and subsequent bony ca

280 that macrophage-specific deletion of ERalpha impaired this M2 polarization.

281 and/or increased insulin resistance (IR) or impaired tissue metabolism is unknown.

282 Patients were impaired to the same extent in the No-Rotation and Rotat

283 atures between patients in XP subgroups with impaired transcription coupled nucleotide excision repai

284 ced levels of H3K4me1 and H3K27ac as well as impaired transcription.

285 d with synthetic ligands and GR mutants with impaired transcriptional abilities.

286 ORF7 deletion also impaired transmission of ORF7-deficient virus among the

287 sm in ECs did not cause energy distress, but impaired tricarboxylic acid (TCA) cycle anaplerosis, mac

288 n, increased SOCS-1 expression, and severely impaired tTreg cell development in embryos, adults, and

289 proliferation and induced apoptosis but also impaired tumorigenicity.

290 , activation of AMPK signaling in muscle was impaired under starved conditions, while mTORC1 signalin

291 delay disease onset but become functionally impaired upon disease progression.

292 unx3 deficiency limited clonal expansion and impaired upregulation of cytotoxic molecules in TEFF cel

293 ty in the hypertrophic chondrocyte layer and impaired vascular invasion.

294 Obese patients have impaired vasodilator reactivity and increased endothelin

295 sibility that Gsalpha knockout may result in impaired VEGF production.

296 ized by ritualistic-repetitive behaviors and impaired verbal/non-verbal communication.

297 adaptive immune response is associated with impaired viral clearance in Nlrc5(-/-) mice.

298 The risk of overall impaired vision increased by 1.20 times (95% CI, 1.01-1.

299 oite colonization in the small intestine and impaired weight gain.

300 sed gene expression, and both mechanisms are impaired when TET2 and nuclear factor kappaB are downreg