ライフサイエンスコーパス: imperative

1 s on graphene based ORR catalysts are highly imperative.

2 en of childbearing age and their partners is imperative.

3 Maximizing their effectiveness is imperative.

4 f measuring appropriate antimicrobial use is imperative.

5 nnotation of cancer cell metabolism genes is imperative.

6 argeting pathogenic T cell responses remains imperative.

7 o future climate driven by increasing CO2 is imperative.

8 the search for new therapeutics is therefore imperative.

9 cting pancreatic cancer at an early stage is imperative.

10 ons and creating new treatment strategies is imperative.

11 h directed toward carbon capture and storage imperative.

12 and substance intoxication and withdrawal-is imperative.

13 e make the search for next-generation agents imperative.

14 ar targets to prevent and/or mitigate EAC is imperative.

15 , and the distinct environment, the NICU, is imperative.

16 fat accumulation and fatty acid spillover is imperative.

17 to those patients most likely to benefit are imperative.

18 ents for pancreatic cancer remain a clinical imperative.

19 alternative mechanisms of action has become imperative.

20 city and drug resistance of C. neoformans is imperative.

21 tion of recipients after transplantation are imperative.

22 across genera, addressing this issue remains imperative.

23 with gliomas, makes biomarker identification imperative.

24 tic targets for metastatic breast cancers is imperative.

25 determinants of oral health disparities are imperative.

26 on, which makes their detection all the more imperative.

27 ote patient safety, procedural competency is imperative.

28 its consequences, prevention of delirium is imperative.

29 the understanding of their binding kinetics imperative.

30 s as pathogenic or non-pathogenic has become imperative.

31 to assess the cell type specific response is imperative.

32 olved in drug resistance or sensitization is imperative.

33 g peoples, represents an entirely achievable imperative.

34 o makes sufficient type one error correction imperative.

35 f novel therapeutic targets for this disease imperative.

36 ity loss across the planet by 2020-an urgent imperative.

37 uction and escape from Nab activity is still imperative.

38 municating the reliability of MFA results is imperative.

39 ess risk for transplant is critical to these imperatives.

40 cipients to be treated at home, and economic imperatives.

41 g that is often needed to satisfy functional imperatives.

42 for addressing climate change to support the imperative acceleration of replacing CVs with EVs.

43 nce make malaria elimination both viable and imperative, although this may be more easily achieved in

44 tunity for surgeons to embrace this national imperative and improve our practices.

45 ack surgery) and nondiscretionary surgery as imperative and potentially life-saving procedures (eg, c

46 00,000 patient-years) but rapid diagnosis is imperative as an emergency surgical procedure is frequen

47 detection of multiple food allergens is thus imperative as food allergies are becoming increasingly r

48 tial biodiversity may have tangible economic imperatives as well as being desirable in terms of emplo

49 close the gap in the care cascade by race is imperative, as are efforts to increase serodiscussion an

50 Ripplocations are a topological imperative, as they allow atomic layers to glide relativ

51 n of endotypes is also becoming increasingly imperative because targeted biotherapeutic agents, such

52 in-injured patients, reliable biomarkers are imperative before any preclinical therapeutics can find

53 Sample outlier detection is imperative before calculating a multivariate calibration

54 ole and dissecting underlying mechanisms are imperative before targeting CAP1 can become a possibilit

55 ibution of causality to detected variants is imperative but imperfect.

56 leopard not only in China, but also through imperative conservation cooperation internationally.

57 inder the delivery of quality cancer care is imperative, especially given the rapidly changing health

58 g coverage and carefully tuned algorithms is imperative for a clinical assay.

59 ensitive Raman spectroscopy measurements are imperative for a large number of applications in biomedi

60 Despite the rarity of POC, it is imperative for a radiologist to be aware of its wide spe

61 Despite its rarity, it is imperative for a radiologist to be aware of this subcuta

62 s the epidemic of tobacco-caused disease, an imperative for action documented by epidemiologic resear

63 Accurate stratification of tumors is imperative for adequate cancer management.

64 g surface modifications and its precision is imperative for attaining the anticipated interaction kin

65 Subsurface analysis of chemical species is imperative for biomedical diagnostics and imaging, homel

66 suggest that complete neutralization is not imperative for bnAbs to prevent infection but that with

67 by the TMTC1-4 genes, which were found to be imperative for cdh and pcdh O-Man glycosylation.

68 ation of a correct base stacking shown to be imperative for deamination activity.

69 rient storage and partitioning in forests is imperative for ecosystem models and ecological theory.

70 of fishing pressure on ecosystem function is imperative for effective coral reef conservation and man

71 ecological and epidemiological processes is imperative for effective disease management.

72 f drug-resistantMycobacterium tuberculosisis imperative for effective treatment and subsequent reduct

73 elaxor-, organic- and anti-ferroelectrics is imperative for exploiting new flexible and room-temperat

74 This information will also be imperative for future research exploring pharmacological

75 ontrolled regulation of lineage decisions is imperative for hematopoiesis.

76 fication of conspecific bacterial strains is imperative for improved understanding of microbial commu

77 novel biomarkers and therapeutic targets are imperative for improving survival.

78 ge carrier generation and their diffusion is imperative for improving the efficiency of optoelectroni

79 tanding of gas exchange mechanism in ARDS is imperative for individualized symptomatic support of pat

80 ng coherence in such a large system would be imperative for its utility.

81 Thus, understanding how to diagnose VHF is imperative for laboratories worldwide.

82 NF-kappaB activation is imperative for latent infection of gammaherpesviruses.

83 are fully developed in the mature liver are imperative for life.

84 It is imperative for low-cost solutions to become a reality, b

85 l malformations, the ZIKV epidemic became an imperative for mobilization, renewed strategies for vect

86 Achieving this goal is imperative for nature and humanity, as people depend on

87 comprehensive list of cancer driver genes is imperative for oncology diagnostics and drug development

88 w work in nontraditional model systems is an imperative for our society to prepare for problems we do

89 se after exposure to a stimulus which can be imperative for proper function.

90 sed payments for bundles of care advance the imperative for radiology providers to articulate their v

91 Reversal of SMC3 acetylation is imperative for recycling cohesin so that it can be reloa

92 The imperative for reform is shown by a looming crisis of vi

93 Here we report that dose escalation is imperative for safe, subcutaneous delivery of the high s

94 Debugging a genome sequence is imperative for successfully building a synthetic genome.

95 nd the path of connectivity is advisable and imperative for the conservation of Hainan's coral reefs.

96 derstanding of spatio-temporal movements are imperative for the conservation of this species.

97 e for the maintenance of neuropathic pain is imperative for the development of more efficacious thera

98 anding the molecular basis of persistence is imperative for the development of new treatments.

99 the discovery of CA IX selective ligands is imperative for the development of these agents.

100 action of Li ions from a cathode material is imperative for the functioning of a Li-ion battery.

101 Accurate replication of DNA is imperative for the maintenance of genomic integrity.

102 to thermal treatments at the atomic scale is imperative for the rational design of catalyst nanoparti

103 ng components capable of these processes are imperative for the realization of multifunctional integr

104 sions using informative molecular markers is imperative for their genetic improvement and conservatio

105 th, and that increased clinical attention is imperative for these pregnancies.

106 We propose that Irf4 is imperative for thymic Treg homeostasis because it regula

107 ving energy intake (EI) over long periods is imperative for understanding obesity and its treatment.

108 here could still be a significant adaptation imperative for vulnerable urban populations.

109 free at the point of care, is a humanitarian imperative for war wounded, and this paper reports the c

110 The coupled imperatives for reduced heat dissipation and power consu

111 oolers and heightened clinical awareness are imperative given the consequences of infection.

112 mpatible, and it may be that this functional imperative has driven IgE to evolve such a dynamic struc

113 Of imperative importance to decipher the complexity of COPD

114 cidating the source of these associations is imperative in achieving the promise of the national Prec

115 ugh inspection of the groin and genitalia is imperative in black organ transplant recipients.

116 r cells, either locally or at distances, are imperative in both normal and pathological conditions.

117 g the various treatment options available is imperative in choosing the proper treatment for each pat

118 transmission in historical Europe, which is imperative in demonstrating how pandemics were spread in

119 Psychomotor findings are imperative in examination of critically ill patients wit

120 and that this downregulation is functionally imperative in mice for acinar reprogramming by oncogenic

121 diagnosis of viral respiratory infections is imperative in patient triage and management.

122 gramming algorithms to minimize RV pacing is imperative in patients with dual-chamber pacemakers who

123 Maintaining proper atrial function is imperative in preventing arrhythmia and thrombus formati

124 p in early detection of melanoma, a clinical imperative in preventing the disease progression.

125 istribution and fluctuational typicality, is imperative in proper evaluation of sequential "randomnes

126 sure to trauma reminders has been considered imperative in psychotherapy for posttraumatic stress dis

127 tegrated plasmonic sources and detectors are imperative in the practical development of plasmonic cir

128 ther research into beta-blocker adherence is imperative in this high-risk population.

129 To address this issue, there is an imperative need for an advanced simulation approach capa

130 association with severe sequels, there is an imperative need for new JIA diagnosis strategies.

131 . urticae chemical adaptation in hopyards is imperative new information that will help growers develo

132 This is the great imperative of our times.

133 the unequal worth of human beings, the moral imperative of preserving a pure Aryan people, the author

134 Recent studies have highlighted the imperatives of including diverse and under-represented i

135 Such efforts are imperative on a global scale.

136 red TiO2 nanotube arrays framework, by which imperative roles of Au nanocrystals as electron relay me

137 Third, we demonstrated the imperative roles of LOXL2 in modifying the extracellular

138 Early diagnosis is imperative so that infected persons can take measures to

139 ations and the cellular adaptive response is imperative so that therapeutic targets can be identified

140 a SAS was delivered simultaneously with the imperative stimulus.

141 Kant's second formulation of the Categorical Imperative, taboos, and love.

142 An imperative task is to translate information/knowledge ac

143 It is imperative that a flexible suite of interventions that t

144 maternal and child health programmes make it imperative that a similar intervention that establishes

145 preserving vision in persons with DME, it is imperative that all persons with diabetes receive early

146 It is imperative that bone tumour margin and extent of tumour

147 It is imperative that both RM and pristine samples are treated

148 ration to electron-positron colliders, it is imperative that both the electrons and their antimatter

149 It is imperative that brain death be diagnosed accurately in e

150 procedures in patients in hospital so it is imperative that clinicians are knowledgeable about appro

151 tions to become a reality, but it is equally imperative that close scrutiny be given to each new devi

152 rfaces in susceptibility to infection, it is imperative that effective mucosal responses are induced

153 pollution sources in the environment, it is imperative that fractionation factors for important biog

154 iduals and societies, but also a development imperative that is good for health.

155 In this context, it is imperative that nephrologists become familiar with this

156 To further reduce ART attrition, it is imperative that patient education and healthcare provide

157 n the complex nature of the procedure, it is imperative that patients are selected appropriately, and

158 impact of TBI on the human population, it is imperative that research remains active in this area and

159 erate large, complicated data sets and it is imperative that signal is properly distinguished from no

160 campal atrophy in Alzheimer's disease, it is imperative that techniques are developed for detection o

161 rder to realize an "overall zT > 2.0," it is imperative that the interrelated properties are decouple

162 It is therefore imperative that the nephrology community capitalize on r

163 It is therefore imperative that the ongoing translational challenges are

164 It is scientifically and ethically imperative that the results of statistical analysis of b

165 It is imperative that these processes are extremely well-coord

166 oundation for evidence-based medicine, it is imperative that this disparity be addressed so that ther

167 It is therefore imperative that water quality management strategies acco

168 It is therefore imperative that we advance our understanding of the invo

169 inant colon cancer screening strategy, it is imperative that we continue to measure and improve the q

170 curity posed by rumen fluke infection, it is imperative that we develop a better understanding of the

171 ed on appropriate placebo comparisons, it is imperative that we establish whether there is an effect

172 The authors believe it is imperative that we expand the use of therapies proven to

173 Thus, it is imperative that we investigate the pathogenesis of adeno

174 nic nitrogen to ecosystems globally makes it imperative that we understand how nutrient supply alters

175 ems intensified from 2000 to 2008, making it imperative that we understand the consumptive processes

176 As AuNP manufacture increases, it is imperative that we understand the environmental fate of

177 CD8 T cell-based vaccines; therefore, it is imperative that we understand the factors controlling th

178 e field of environmental epidemiology, it is imperative that we understand the methodologic challenge

179 In the era of pay for performance, it is imperative that we understand the quality measures under

180 ancy and during labour and childbirth, it is imperative that with INAP in place, India aspires to doc

181 ptic nonreciprocal systems on chip have made imperative the exploration of magnet free alternatives.

182 positional analysis in biofuel feedstocks is imperative; the yields of individual components can defi

183 ges of components in the mass spectra, it is imperative to accurately determine a noise threshold lev

184 s to prevent postnatal HIV-1 transmission is imperative to achieve a generation free of HIV-1.

185 lains how kinetic gating in the D-channel is imperative to achieving high proton-pumping efficiency i

186 ity of the lithium (Li) metal battery, it is imperative to address the dendrite growth and interface

187 zation of patient selection for treatment is imperative to avoid adverse effects without clinical ben

188 Detection of pathogenic bacteria is imperative to avoid and/or fight their potential harmful

189 ated synaptic activity and TrkB signaling is imperative to BDNF's suppressive effect on drug-seeking.

190 lmark of many pathophysiological process, is imperative to both understanding the precise roles of RO

191 e forced to close for lack of accrual, it is imperative to build multidisciplinary consensus before t

192 Imperative to capture patient-reported outcomes was driv

193 Therefore, it is imperative to carefully consider experimental design bef

194 Therefore, it is imperative to carefully consider experimental design bef

195 achieved using these strategies, it will be imperative to carefully monitor for the potential risks

196 and post-blast neurological sequelae, it is imperative to characterize the initiating traumatic mech

197 elk now suffering a CODD-like disease, it is imperative to clarify these disease etiologies.

198 or plant metabolism of these CECs, making it imperative to consider conjugates when assessing their r

199 the interrogation of African genomes, it is imperative to continue and increase our efforts to descr

200 our understanding of how MXCs operate, it is imperative to continue modeling efforts in order to effe

201 A multifaceted approach is imperative to control and prevent nosocomial influenza i

202 therapeutic antiviral drugs against hRSV is imperative to control the burden of disease in the susce

203 vaccine and diagnostic antigen design, it is imperative to delineate complete IgG-epitome of the prot

204 s area in recent years, but there remains an imperative to demonstrate that the current densities rep

205 ine responses in African populations will be imperative to design effective vaccines for protection a

206 vivo generated dendritic cells (DCs), it is imperative to design strategies that harness specialized

207 Therefore, it is imperative to determine the ability of strains to faithf

208 dults and women of childbearing age makes it imperative to determine the long-term effects of METH ex

209 parents in a nuclear family therefore it is imperative to determine the nitrate and nitrite content

210 increase the number of failed trials, it is imperative to determine what is causing this trend.

211 ber of BL enzymes is increasing daily, it is imperative to develop a computational tool to classify t

212 ge carrots for high carotenoid content it is imperative to develop a fast and non-destructive techniq

213 uences than substitutions do, and thus it is imperative to develop a method to reliably calculate the

214 uences than substitutions do, and thus it is imperative to develop a stochastic evolutionary model th

215 as a routine conservation methodology, it is imperative to develop chemometric indicators with the ab

216 sion with current antidepressants, making it imperative to develop more effective treatment.

217 herapy for treating human cancer has made it imperative to develop new tools to measure early events

218 Thus, it is imperative to develop noninvasive biomarkers for detecti

219 by microorganisms on medical implants, it is imperative to develop novel antimicrobial biomaterials.

220 analysis has unique challenges, since it is imperative to distinguish circulating DNA from normal ce

221 ing degrees of physiological tremor so it is imperative to distinguish physiological tremor from path

222 Hence it is imperative to elucidate the rheological properties of li

223 eloping a posttransplantation malignancy are imperative to ensure appropriate measures are instigated

224 n expression and pharmacokinetics in vivo is imperative to ensure successful individualized treatment

225 It is imperative to examine care and service provision for thi

226 shape and interactions, and it is therefore imperative to examine facilitation in complex glass form

227 d habitats of many endangered species, it is imperative to explore an adaptive strategy for the decli

228 pply chain and pricing instabilities make it imperative to explore rare earth free magnetic materials

229 Therefore it is imperative to explore the mechanisms that result in LSC

230 reasing obesity prevalence in children it is imperative to explore the role of EDC as obesogens.

231 There is also a growing imperative to extend cancer epidemiology research that i

232 tleneck for many studies and it is therefore imperative to extract as much information as possible fr

233 Therefore, it is imperative to find environmentally-friendly metal ions t

234 Consequently, there is an imperative to foster workforce innovation to ensure sust

235 completed Phase III clinical studies, it is imperative to gain a better understanding of its mechani

236 cture in a dynamically controlled way, it is imperative to gain access into the intrinsic dynamics of

237 There is an ethical imperative to generate evidence at an early stage to sup

238 organ allocation and overall outcomes, it is imperative to have accurate characterization of the immu

239 The moral imperative to honor their collective sacrifice is the tr

240 obal increase in salinity levels has made it imperative to identify novel sources of genetic variatio

241 however, molecular and genomic work remains imperative to identify target populations that will trul

242 To combat this challenge, it is imperative to identify the mechanisms of arsenic mobiliz

243 The imperative to identify vaccine targets is driven both by

244 Such standards are imperative to implementing summative assessments into su

245 Combinatorial therapeutic approaches are an imperative to improve cancer treatment, because it is cr

246 r relapse after initial treatment remains an imperative to improve survival.

247 n in all potential transplant candidates are imperative to improve the overall graft and patient surv

248 n (N) and phosphorus (P) in urban systems is imperative to improving water quality and better managin

249 ost likely to benefit from HEMS transport is imperative to justify the risks and cost of this interve

250 and imaging studies were negative if it was imperative to know whether active Crohn's disease was pr

251 The imperative to maximize organ utility must be balanced ag

252 o properly understand these processes, it is imperative to measure them in a time-dependent way and a

253 It is therefore imperative to mitigate cationic charge-induced toxicity

254 To further improve device performance, it is imperative to obtain fundamental understandings on the p

255 magnitude between individuals, making it an imperative to obtain individual baseline measurements if

256 example greywater, such an understanding is imperative to optimize designs for successful long-term

257 Understanding this role is now imperative to optimize methane production from LCFA.

258 ater relations of microbial extremophiles is imperative to our ability to increase agricultural produ

259 yses of site-specific antibody responses are imperative to our assessment of the quality of vaccine-i

260 inking depends not only on the physiological imperative to protect the eyes and spread a film of tear

261 especially in a point-of-care setting, it is imperative to quantify them directly in complex biologic

262 Besides mortality and hospitalization, it is imperative to realize that patients with HFpEF have sign

263 It is imperative to reconcile SSI monitoring, develop consiste

264 Optimal treatment initiatives remain imperative to reduce the ocular complication-related bur

265 large variation between instruments makes it imperative to regularly quantify this effect on individu

266 It is thus imperative to resolve the mismatch between the physiolog

267 Although a clinical diagnosis, imaging is imperative to rule out associated complications which ap

268 Therefore, there is an imperative to search for new drug targets in S. haematob

269 It is imperative to simultaneously achieve hierarchical struct

270 t the PD of VGCC undergoes hysteresis, it is imperative to study its gating process in the absence of

271 stand community composition, it is therefore imperative to study the impact of resource fluctuations

272 fitness in their environmental niches, it is imperative to study viruses at the site of initial repli

273 In myeloid malignancies, there is a clinical imperative to test for such mutations in mainstream diag

274 Finding solutions to these problems is imperative to the future of cancer care.

275 gens to the carrier protein is thought to be imperative to the immunological properties of conjugate

276 arly with a relevant concentration range, is imperative to the timely assessment of human diseases an

277 adily in the past several decades, making it imperative to understand all aspects of their ecology.

278 echanisms of perception and cognition, it is imperative to understand brain networks at an algorithmi

279 As the field moves forward, it will be imperative to understand each person's pain from its own

280 s are being lost at alarming rates and it is imperative to understand how communities assemble if we

281 It is imperative to understand how naturally mediated changes

282 ium and sodium ion battery technology, it is imperative to understand how the properties of the diffe

283 auses of autism spectrum disorder, making it imperative to understand how the Shank family regulates

284 slow the rate of global species loss, it is imperative to understand how to restore and maintain nat

285 It is imperative to understand its damage-tolerant behaviour a

286 thione and redox homeostasis, and thus it is imperative to understand the enzymes and the mechanisms

287 It is therefore imperative to understand the etiology of these distinct

288 re environmental conditions, then it becomes imperative to understand the impacts of pathogens on cro

289 fungal pathogens have on human health, it is imperative to understand the molecular mechanisms that g

290 These policy mechanisms have made it imperative to understand the potential cost savings of q

291 ay be detrimental to bacterial growth, it is imperative to understand the strategies employed by bact

292 s affecting forebrain development, making it imperative to understand the underlying genetic circuitr

293 e of antimicrobial resistance (AMR) makes it imperative to understand the underlying mechanisms.

294 Consequently, it is imperative to understand the uptake of accumulation of N

295 It is imperative to understand these processes and quantitate

296 tanding MDR pathogen dynamics, it has become imperative to unify AR gene data resources for easy acce

297 We propose policy imperatives to protect and support health workers workin

298 control must be seen as both a public health imperative unto itself and a vital component of economic

299 To deal with these imperatives, we synthesized for the first time TiO2 NPs

300 Two analytical imperatives were sought: (1) overall simplification in d