ライフサイエンスコーパス: imperfectly

1 mal microRNAs, which pair with their targets imperfectly.

2 occur more rapidly during childhood and are imperfectly accounted for by statistical corrections tha

3 ttractant serine is shown to be biphasic yet imperfectly adapted, that is, the response function has

4 f wild-type (WT) hairs arises from fields of imperfectly aligned follicles, and that the Fz6(-/-) hai

5 rganize the folding process and largely, but imperfectly, anticipate the native secondary structure.

6 As) are small endogenous RNAs that typically imperfectly base pair with 3' untranslated regions (3'UT

7 tion of the initial pri-miRNA cleavage is an imperfectly base-paired duplex of approximately 15 nt be

8 Although Dicer will cleave both imperfectly base-paired hairpin structures (pre-miRNAs)

9 that has the potential to self-prime at the imperfectly base-paired TAR hairpin, making continued DN

10 mal to potential target sites that base pair imperfectly but extensively to 21U-RNAs.

11 ide a thumbnail view of folliculogenesis but imperfectly capture the dynamic cellular interactions th

12 piRNAs silence transcripts in trans through imperfectly complementary sites.

13 ified a functional miRNA target site that is imperfectly complementary to the BPCV1 miRNA.

14 of gene repression by other miRNAs that are imperfectly complementary to their targets, lin-28 downr

15 RNAs that contain elements to which they are imperfectly complementary.

16 e constructed a variant library by targeting imperfectly conserved noncatalytic loop residues and exa

17 that a somatic recording electrode can only imperfectly control the voltage in the rest of the cell.

18 sodic and phonological information, which is imperfectly correlated with syntactic units and linguist

19 h protein abundance, but these two are often imperfectly correlated.

20 functional impairment are substantially but imperfectly correlated.

21 position of the variants in the protein are (imperfectly) correlated with the severity of the disorde

22 er the AP(4)N family, whose functions remain imperfectly defined, of intracellular molecules was disc

23 emphasized that dysphagia frequently remains imperfectly diagnosed; some of these newer less expensiv

24 achieve a large effect if scaled up even if imperfectly efficacious.

25 ssibilities are that toxicity may arise from imperfectly folded mutant SOD1 catalyzing the nitration

26 histidine at position 41 substitutes, albeit imperfectly, for His-42 in peroxidative turnover of the

27 GIE is the presence of microdeletions at the imperfectly homologous breakpoints.

28 While direct repeats and imperfectly homologous sequences appear to mediate the f

29 solutely for the exclusion of "homeologous" (imperfectly homologous) tandem deletion.

30 Free capture probes (CPs) and imperfectly hybridized CPs are digested while the perfec

31 enzyme (Surveyor((R)) nuclease) cleaved the imperfectly hybridized wild-type gene together with all

32 Surveillance data imperfectly indicate current prevalence and risk factors

33 orresponding mutational spectra to the often imperfectly known physiologies of the proteins encoded b

34 power when control data are limiting or even imperfectly matched ancestrally.

35 are processed from longer RNA molecules with imperfectly matched foldback regions and they function i

36 tide RNA duplex from a precursor in which an imperfectly matched inverted repeat forms a partly doubl

37 tes that RGNs can be highly active even with imperfectly matched RNA-DNA interfaces in human cells, a

38 the mechanism by which recombination between imperfectly matched sequences (homeologous recombination

39 DeG, a computational algorithm which designs imperfectly matched sequences (previously yielding only

40 ombination-dependent exchanges between often imperfectly matched telomeric sequences.

41 untranslated region (3'UTR) and one that is imperfectly matched.

42 ctivity of Surveyor((R)) nuclease toward all imperfectly-matched DNA duplexes produced an ultrahigh s

43 he sequence alignment of the exodomain shows imperfectly matching eight to nine Leu-rich repeats (LRR

44 Although energy intake is known to be imperfectly measured by questionnaire, we observed a pos

45 limits of standard methods of control for an imperfectly measured confounder, have been understood fo

46 derestimated associations, and unmeasured or imperfectly measured covariates may have caused residual

47 Unmeasured or imperfectly measured covariates may have caused residual

48 To estimate the net effect of imperfectly measured highly active antiretroviral therap

49 artly explained by residual confounding from imperfectly measured or unmeasured variables.

50 model of chronic myelogenous leukemia (CML) imperfectly mimics human CML because the murine CML-like

51 PA) is a well-known endocrine disruptor that imperfectly mimics the effects of physiologic estrogens

52 scenarios in which a user interacts with an imperfectly modelled or 'untrusted' system.

53 for uncertainty in the data by imputing the imperfectly observed colonization status of patients ove

54 n overt disease, so transmission can be only imperfectly observed through a sequence of surveillance

55 plete surveillance data, and the underlying, imperfectly observed, system.

56 ely that payoffs and asymmetries may both be imperfectly observed.

57 to a zinc ion pair in the active site but is imperfectly oriented to launch a nucleophilic attack on

58 d and found that they can regenerate, albeit imperfectly, over several hours.

59 The AFF4-ELL2 interface is imperfectly packed, leaving a cavity suggestive of a pot

60 t of an engineered gRNA-Cas9 was found on an imperfectly paired genomic site, but it had lower genome

61 Mice (MVM) are extended and copied to create imperfectly palindromic duplex junction sequences that b

62 us branches of hosts' immune systems and the imperfectly perceived pathogen.

63 ctical factors such as harmonic trapping and imperfectly point-like interactions may compromise integ

64 Since the current staging system imperfectly predicts outcome in patients with such lesio

65 Although animal models of fibrosis imperfectly recapitulate IPF, they have yielded numerous

66 Such damage, if imperfectly repaired, would result in solar scars, which

67 There are four imperfectly repeated copies of this motif in each set of

68 The mammalian CTD consists of 52 imperfectly repeated heptads followed by 10 additional r

69 ides with two active-sites or an internally, imperfectly repeated polypeptide that retains a single H

70 ion proteins, we searched among the CTD's 52 imperfectly repetitive heptapeptides for the minimal sub

71 e sufficiently similar that each complex can imperfectly replace the other.

72 cs can moderate this selective constraint by imperfectly resembling multiple models [5], through poly

73 ts demonstrate that iPSC genomes can exhibit imperfectly rewired 3D-folding linked to inaccurately re

74 king region of SLC1A1 was also detected that imperfectly segregated with OCD in a large, multigenerat

75 l clustering increases robustness to long or imperfectly selected input sequences.

76 mine) and diltiazem (a benzothiazepine) were imperfectly selective, so differences in the state depen

77 overlapping bands, and in particular allows imperfectly shaped bands to be accurately modeled.

78 of tuning curves can be recovered even from imperfectly sorted neurons.

79 subjects learned these expectations, albeit imperfectly, then used them to make decisions in accorda

80 l into only two discrete categories that map imperfectly to the underlying genes.

81 ne expression allow the gut to adapt, albeit imperfectly, to their toxicity.

82 nosis of the terminal bowel), which is still imperfectly treated.

83 arum erythrocyte invasion depends on several imperfectly understood multiprotein families.

84 virus (IAV) infection leads to variable and imperfectly understood pathogenicity.

85 es exhibit a wide range of extraordinary but imperfectly understood phenomena.

86 The molecular mechanisms are imperfectly understood, although an activated renin-angi

87 the female's antenna play a crucial, if yet imperfectly understood, role in sensing oviposition cues

88 its degradability in the environment remains imperfectly understood.

89 he mechanism of action of biguanides remains imperfectly understood.

90 actors that impel sleep after sleep loss are imperfectly understood.

91 nvironmental transformation reactions remain imperfectly understood.

92 d its origins and modes of dissemination are imperfectly understood.

93 al Insitutes of Health allocations correlate imperfectly with disease burden, with cancer and HIV/AID

94 ling that PIK3CA variant activity correlates imperfectly with its mutation frequency across breast ca

95 Data from the 2 groups overlap imperfectly with respect to measurements made: the large

96 e entry and exit gates act cooperatively but imperfectly, with neither being able to restrict phospha