ライフサイエンスコーパス: impetus

1 y, and they have given these disciplines new impetus.

2 This provides powerful impetus and a growing demand for researchers to develop

3 These results provide impetus and further guidance for the development of thes

4 ly mammalian embryogenesis, which provide an impetus and opportunities for future investigations.

5 nd-targeted nanoparticles have been the main impetus behind the progress of nanomedicines towards the

6 The impetus behind these reports comes from different source

7 ally one stem cell type that, with the right impetus, can create whatever progeny our heart, liver or

8 tion number of a trigonal-planar geometry is impetus enough to make even the electronegative cobalt w

9 ions addressed by this research provided the impetus for a decades-long effort-still in full force to

10 ar follow-up in isolated MR and provides the impetus for a large-scale clinical trial with clinical o

11 a subgroup of tinnitus patients and provides impetus for a larger pivotal study.

12 arative organismic biology have provided the impetus for a major re-evaluation of the earliest phases

13 The main impetus for a mini-symposium on corticothalamic interrel

14 ctive immunity in animal models, fueling the impetus for a vaccine.

15 This has provided the impetus for active study of the design of degradable mat

16 gh alternative novel mechanisms and provides impetus for additional investigation.

17 This study provides further impetus for additional research into the influence of mo

18 vous and/or skeletal systems and provide the impetus for additional studies aimed at identifying the

19 nnel 6 (TRPC6) protein, which is the genetic impetus for an autosomal dominant form of FSGS.

20 conducted at Memorial Hospital served as the impetus for an intergroup adjuvant E1694/S9512/C509801 t

21 This observation provides impetus for analysis of other complex networks of side-c

22 anisms of normal physiology but also provide impetus for application of these findings to studies of

23 on of the RNase A superfamily, as well as an impetus for applying this methodology to other ribonucle

24 have stirred controversy and have become the impetus for calls to abandon recommendations for reduced

25 m those in water and can provide some of the impetus for catalytic processes.

26 ence, with random fluctuations as sufficient impetus for cell reorganization.

27 These observations should represent an impetus for change and improvement in the preparticipati

28 Adding to the impetus for change are the attendant realities of the jo

29 without high costs is required to provide an impetus for change.

30 ed rhythmicity, in addition to providing the impetus for circadian oscillations in general.

31 cetylcysteine in this mouse model provide an impetus for clinical evaluation of glutathione repletion

32 ngaged by IL-18/IL-2 and provide preclinical impetus for clinical investigation of this potent anti-t

33 cardiac myocyte contractility, providing an impetus for compensatory hypertrophy.

34 ern through clinical observations, providing impetus for deeper investigation of the disease subtypes

35 ssure-distance paradox and predicts that the impetus for defect plane insertion is tunable via variat

36 reased demand for services have provided the impetus for delivering team-based primary care.

37 ase progression and involvement has provided impetus for design of new enzyme therapies, and creation

38 l, no vaccine, and insufficient access to or impetus for developing affordable new drugs.

39 in clinical brain tumor therapy provides an impetus for developing new treatments as well as methods

40 of the current process provide an essential impetus for developing newer separation protocols, most

41 These data will hopefully provide the impetus for development of novel compounds that use mult

42 acy of AR antagonists, thus establishing the impetus for development of RD-based mimetics.

43 n of L-nucleoside analogs, providing further impetus for discovery and clinical development of new ag

44 nic effects in diabetic patients and provide impetus for efforts to develop PPARgamma ligands that se

45 Our study provides an impetus for elucidating the molecular determinants that

46 nerations that have continued to serve as an impetus for empirical investigation during the 1990s--an

47 generally, this emit-receive concept is the impetus for enabling new signal processing schemes.

48 Our data reduce the impetus for equating Sho with the notional pi protein an

49 The pursuit of happiness and reward is an impetus for everyday human behavior and the basis of wel

50 The impetus for examining microbial communities in different

51 erse array of pathologies, and provide a new impetus for exploiting this fascinating recognition syst

52 These results provide an impetus for exploring earlier shock delivery in implanta

53 modulate soluble and bound signals provides impetus for exploring mechanobiology paradigms in regene

54 cal models on the origin of species, and new impetus for exploring putative plant and animal examples

55 Moreover, our results provide further impetus for exploring the helix alphaC patches of other

56 The impetus for framing this question lies in the current in

57 during eukaryotic evolution, and provide the impetus for further detailed studies of the possible evo

58 This study provides impetus for further development of a safe, highly effect

59 me in burned humans, and our results provide impetus for further investigation of the role of the inf

60 Our findings provide impetus for further investigation of this compound as a

61 amination; however, they do provide a strong impetus for further monitoring and analysis of groundwat

62 s hoped that this framework will provide the impetus for further research and discussion and will lea

63 rtance of TRPA1 in cold exposure and provide impetus for further research into developing therapeutic

64 as well as prostatic cancer and will be the impetus for further studies of hK2 distribution and func

65 thymidylate metabolism and provides a major impetus for further studies on TLD.

66 anticipated that these data will provide an impetus for further studies to determine injury severity

67 This data provides impetus for further studies to determine its viability a

68 inistration of a rAAV vector and provide the impetus for further studies to exploit its use as a tool

69 ble therapeutic resistance, has provided the impetus for further study into how Mcl-1 is involved in

70 new role for Htt in translation and provide impetus for further study into the link between protein

71 onged progression-free survival) provides an impetus for further study of HDM2 inhibitors in liposarc

72 nd its oxidation products for U(VI) provides impetus for further study of mackinawite as a potential

73 utologous nature of this biomaterial provide impetus for further translation.

74 These findings may provide an impetus for future investigations of supplemental nucleo

75 These findings provide impetus for future investigations on nanoparticle-mediat

76 l roles in vivo and provides a framework and impetus for future larger-scale functional investigation

77 The results of this study provide impetus for future positional cloning of QTLs regulating

78 These results provide impetus for future positional cloning of quantitative tr

79 ther gammaherpesviruses and thus provides an impetus for future studies analyzing the role of the gam

80 be considered "hypothesis generating" and an impetus for future studies regarding the effects of foli

81 This study provides impetus for future work in motion perception and its rel

82 Our results provide an impetus for gaining a deeper understanding of ANO1 modul

83 The law also provides impetus for greater collaboration between the US health-

84 These stochastic events can provide the impetus for heritable phenotypic change in bistable epig

85 dent of the major death pathways and provide impetus for identification of novel death pathways preci

86 ally overexpressed has provided an important impetus for identifying activators of utrophin expressio

87 Health care purchasers can provide the impetus for implementing the information framework if th

88 by SIV infection in the CNS may provide the impetus for increased transcription of MAO B and that MA

89 This provided an impetus for intense research into the mechanisms of modu

90 t these results will provide methodology and impetus for investigating iso-CoA compounds as potential

91 Our results may trigger a renewed impetus for investigating structural differences in the

92 ncept of vascular depression can provide the impetus for investigations of prevention and treatment o

93 acial foragers, perhaps providing an initial impetus for investment in ceramic container technology,

94 of 99mTc-sestamibi tumor uptake provided the impetus for its evaluation as an adjunctive technique.

95 and how seminal research studies provide an impetus for its public health policy and programs.

96 Our findings provide impetus for larger trials to assess the effects of vitam

97 lar "metabolic flux" was proposed as a novel impetus for metabolic regulation.

98 zed using a biomimetic process, and that the impetus for mineral nucleation in this system appears mo

99 Rather than serving as an impetus for mitochondrial ATP generation, matrix NADH ra

100 t this critical assessment will increase the impetus for more carefully considered and rigorous desig

101 r cardiovascular events and provides further impetus for more directly testing this hypothesis at pop

102 of biodiversity loss and should serve as an impetus for new biodiversity experiments.

103 been disappointing, therefore providing the impetus for novel combination drug trials.

104 hanism inherent to pathogens and provide the impetus for preparing second generation analogues as a p

105 The impetus for rapid results is the availability of effecti

106 Finally, MSC/CD34(+) grafts provided the impetus for rapid urothelium regeneration.

107 evious conflicting results and constitute an impetus for reanalyzing previous data sets, taking into

108 tion and lineage commitment and provides new impetus for reexamining lineage models.

109 nships for numerous operations, providing an impetus for regionalization; however, volume-based regio

110 ord and divorce will continue to provide the impetus for research on more effective means of interven

111 al carbon nanotubes (CNTs) have provided the impetus for researchers in developing high-performance c

112 with hypersexuality provides a motivational impetus for seeking this reward behaviour through activa

113 However, its phenotypic consequences and impetus for selection are not well understood.

114 e implications of this study may serve as an impetus for similar improvement efforts.

115 This has led to an impetus for the chemical synthesis of oligosaccharide fr

116 e-molecule biophysics has provided a renewed impetus for the construction of quantitative models of b

117 isease is an ongoing threat and serves as an impetus for the continued development of novel approache

118 the E2F transcription factors provide growth impetus for the continuous proliferation of melanoma cel

119 pted daily requirements has provided a major impetus for the critical examination of dietary approach

120 Finally, these observations provide the impetus for the design of a new family of inhibitors of

121 ne-nucleation mechanism and could also offer impetus for the design of new 3D spatial structures of g

122 oral therapy is identified as a second major impetus for the design of oral cytotoxics.

123 s of surgical interventions has provided the impetus for the development of a catheter-based approach

124 ic myelogenous leukemia, has created a great impetus for the development of additional kinase inhibit

125 These data provide the impetus for the development of an attenuated HTLV-2-base

126 The findings may provide an impetus for the development of DPP-4 inhibitors for the

127 om several disadvantages, and there is great impetus for the development of improved methods for sulf

128 key in the OP mechanism, thus giving further impetus for the development of malaria vaccines targetin

129 e-threatening side effects and have provided impetus for the development of more selective anti-clott

130 he anti-CSC properties of 1 provide a strong impetus for the development of new metal-based compounds

131 These findings provide impetus for the development of new therapeutic agents.

132 disrupting the association with Hdm2 was the impetus for the development of Nutlin3.

133 atial and temporal resolution, providing the impetus for the development of synchrotron facilities us

134 t for tuberculosis treatment has provided an impetus for the discovery of adjunctive host-directed th

135 ting of conserved sequences, may provide the impetus for the evolution of composite mobile genetic el

136 oproteins, such as HA, may have been a major impetus for the evolutionary establishment of this recyc

137 These data provide further impetus for the ex vivo use of anti-CD40L mAb to block G

138 Polynesian motif, perhaps also providing the impetus for the expansion into Polynesia.

139 The presented data serve as impetus for the further development of the ec-LLS proces

140 These results provide new impetus for the generation of selective Mcl-1 inhibitors

141 y toxicity testing of chemicals provides the impetus for the incorporation of novel methodologies int

142 , the Toll receptors of the fly provided the impetus for the investigation of Toll-like receptors, wh

143 uality improvement initiatives and potential impetus for the regionalization of important NICU resour

144 in hypertensive populations, and provided an impetus for the search for cortisol-sparing CYP11B2 inhi

145 These findings should provide further impetus for the search for measures to prevent or delay

146 atment of complex abdominal EVAR and provide impetus for the standardization of these techniques in t

147 ately 37% at the basal layer) is the driving impetus for the start of cell migration after injury whe

148 Impetus for the study derives from the need to perform d

149 ratory virus infection, and they provide the impetus for the study of this treatment regimen in RSV-i

150 Our experiments should provide further impetus for the treatment of children with congenital ca

151 Cav-1 via autophagy, which provides further impetus for the use of antioxidants in anticancer therap

152 use visual cortex and should provide further impetus for the use of mice in studies on the genetic an

153 Much of the impetus for the use of radiofrequency ablation has come

154 The main impetus for these changes, which are more intensive than

155 from trans-acting factors-have provided the impetus for these discoveries.

156 The impetus for this approach was that SR FT-IR microspectro

157 These latter findings serve as an impetus for this current review to assess the optimal se

158 The impetus for this move stems from several considerations,

159 The impetus for this recommendation is based on recent appre

160 The conference provided the impetus for this Review, which describes, in historical

161 The impetus for this study was our desire to evaluate the po

162 genetic base of pigs is unknown and was the impetus for this study.

163 The impetus for this work is to help resolve large discrepan

164 This may provide some impetus for those sedentary to become more active.

165 ercialization of cognitive neuroscience, the impetus for training in ethics, and the increased attent

166 , issue of Genes & Development, provides the impetus for uncovering the mechanistic and functional pr

167 After the impetus for understanding the influence of social and cu

168 forbiddenness" of concerted reactions and an impetus for untold numbers of research projects.

169 /off combinations, thereby providing further impetus for use of the 2C7 epitope in a gonococcal vacci

170 tween normal and necrotic myocardium was the impetus for widespread clinical use for demonstrating th

171 ly tunable ligand system may provide further impetus for work in this important area of catalysis.

172 es in the nervous system has received strong impetus from a recent series of important experimental f

173 Nevertheless, there has been an impetus from experts in the field to modify these defini

174 to optimize health benefits and will provide impetus from health systems for the preservation of ecos

175 (hRSV) vaccine development has received new impetus from structure-based studies of its main protect

176 tem structure and function have received new impetus from the federal Brain Research through Advancin

177 f these enzymes in bacteria, probably due to impetus from the primary oxygenation event in Earth's hi

178 ration across multiple organizations for its impetus in improving research quality, advancing efficie

179 ognitive theories have received considerable impetus in regard to both human and animal learning from

180 The current impetus in research concerns establishing the underlying

181 Nanomedicines have provided fresh impetus in the fight against cancer due to their selecti

182 Impetus includes indications that EPO affects significan

183 This impetus is largely a result of the 2005 Institute of Med

184 At the turn of the 20th century under the impetus of anesthesia, such surgical stalwarts as Mayo R

185 ems in a simpler formalism is the underlying impetus of biological sciences.

186 Spindle defects are not only an impetus of chromosome instability but are also a cause o

187 The impetus of earlier newborn discharge places increased em

188 Under the impetus of the Human Genome Project, new disease-associa

189 The impetus of these efforts is to learn from the microbes t

190 oblem of long-standing interest, with recent impetus provided by the relevance of these issues to the

191 The LC might provide the impetus to act when the predicted outcome value is low.

192 an (18)F-FDG-based approach, it provides an impetus to better characterize the determinants of (18)F

193 The recent surge in obesity has provided an impetus to better understand the mechanisms of adipogene

194 For still others, this may provide some impetus to better understand the origins of modern imagi

195 Tax incentives can provide a large financial impetus to change behavior.

196 This will hopefully provide the necessary impetus to change the culture of the training environmen

197 ary pharmacokinetic (PK) profile provided an impetus to change the pharmacophore from a bisaryl urea

198 ary pharmacokinetic (PK) profile provided an impetus to change the pharmacophore from a bisaryl urea

199 e immunostimulatory effects has provided the impetus to combine chemotherapy and immunotherapy for sy

200 ing reversible contraception provides strong impetus to define immunomodulatory properties of this ex

201 multiple genetic causes will provide further impetus to describe the pathway leading to PD.

202 inity of compounds 2d-g to PKCs gives us the impetus to design additional molecules that would retain

203 rmative developmental processes provides the impetus to design and implement randomized control trial

204 This mechanism provides the impetus to design DNA damaging agents that produce DSBs

205 t mammary cancer in an animal model provides impetus to determine its activity in a clinical setting.

206 ynaptic plasticity in the brain, and provide impetus to develop 3'-O-Me-EC-Gluc and other brain-targe

207 as active electronic components provided the impetus to develop a variety of experimental platforms t

208 There remains a continued impetus to develop and amass experience with new therape

209 The current lack of treatment for DEB is an impetus to develop gene therapy strategies that efficien

210 The lack of therapy for DEB provides an impetus to develop gene therapy strategies.

211 heir functions elucidated, providing a major impetus to develop gene-based treatments.

212 ur original hypothesis and providing further impetus to develop Gpr17 antagonists for the treatment o

213 e resistant to this treatment, providing the impetus to develop molecules that sensitize cells to ion

214 These data provide the impetus to develop new therapeutic interventions for tel

215 remediation has inspired a recent scientific impetus to develop oil-absorbing smart nanomaterials.

216 This study also provides an impetus to develop personalized immunotherapy targeting

217 naging in-stent restenosis have provided the impetus to develop provisional stenting strategies.

218 These observations provide an impetus to develop strategies directed toward generating

219 hortage of transplantable organs provides an impetus to develop tissue-engineered alternatives.

220 acteria in recent years have provided strong impetus to discover new antibiotics and alternative trea

221 ocation and their untapped potential provide impetus to discover strategies to turn them against tumo

222 esting that Vps5p may provide the mechanical impetus to drive vesicle formation.

223 gs that evolved from them, that provided the impetus to establish in 1955 the national drug developme

224 ed cirrhosis mortality, and provides further impetus to evaluate coffee as a potential therapeutic ag

225 human host defense apparatus provide further impetus to evaluate the mouse as a model for studying th

226 This work should provide an impetus to experimentalists for designing better electro

227 These findings may provide impetus to exploit the role of Ad-36 proteins as novel t

228 ber of factors have coalesced to provide the impetus to explore alternative renewable sources of carb

229 other microtubule stabilizers, provides the impetus to explore the therapeutic potential of this sit

230 Our findings provide an impetus to further explore Aspm's role in facilitating W

231 es to the inner core saccharides provides an impetus to further explore this compound as a vaccine ca

232 is hoped that these results will provide an impetus to further research and act as a useful benchmar

233 concerns understood to provide the necessary impetus to go to the clinic.

234 e in humans and nonhuman primates have given impetus to identification of host tropisms and potential

235 diverse roles attributed to DC-SIGN provide impetus to identify ligands that can be used to explore

236 This has provided impetus to identify other co-inhibitory receptors that c

237 tes in experimental animal models, providing impetus to identify pharmacological approaches to modula

238 t of expression profiling has provided a new impetus to identifying clinically useful prognostic mark

239 For this reason, there is impetus to implant children at a very young age, as a co

240 ropriate funding will be required to provide impetus to implement these recommendations.

241 nterest in exploring the deep ocean provides impetus to increase our understanding of the deep-sea pi

242 ication rate, not temperature per se, as the impetus to increase the expression of the OspC and Erp i

243 early single-center trials that provided the impetus to initiate phase 3 trials.

244 These data provide impetus to investigate how baseline COX-2 expression is

245 ation of mTOR activity, therefore, providing impetus to investigate if a leucine-sensing mechanism in

246 Our study provides the impetus to investigate whether manipulation of splicing

247 e responses of self-reactive T cells, giving impetus to manipulation of this pathway for treating hum

248 regulate a myriad of target genes, providing impetus to many laboratories to identify these genes.

249 modulating radiosensitivity and provides the impetus to monitor the influence of Prx1 levels in the m

250 re sepsis patients (PROWESS trial) that gave impetus to new directions for basic and preclinical rese

251 , in the last few decades gave a significant impetus to powerful functionalization of indoles at virt

252 two zinc fingers of NCp7, thus providing an impetus to pursue development of highly selective zinc f

253 nematode Caenorhabditis elegans provided the impetus to re-examine the end structure of mammalian tel

254 The impetus to reduce the trauma of surgery witnessed over t

255 new studies in the past 2 years serve as an impetus to reframe the debate into a reasonable discussi

256 These data provide new impetus to resolve how store Ca(2+) content is sensed an

257 tation of baseline probabilities and has the impetus to restore them.

258 of retinal degeneration, and they provide an impetus to restrict excessive light exposure as a protec

259 ignals involved, will soon provide a further impetus to stem cell biology with far reaching applicati

260 cycle functions of cyclin D1 and provide the impetus to study its pleiotropic effects in androgen-dep

261 ring telomerase activity thus provides ample impetus to study the biogenesis and regulation of this e

262 erged as problematic pathogens, providing an impetus to study the potential of PNAG to be targeted fo

263 Their findings provide further impetus to study these molecules and associated signalin

264 lts for the specified wavelength serve as an impetus to suggest the need for two independent measurem

265 advances in stem cell biology have given new impetus to the "cancer stem cell hypothesis." Two import

266 ance with documented absence of CAN may give impetus to the clinical application of tolerance.

267 ding to the dominant helper epitopes, giving impetus to the development of a similar approach in the

268 in ALK translocation-driven cancers, lending impetus to the development of novel anaplastic lymphoma

269 shed or pulled from the animal, and provides impetus to the development of pultrusion-based biomimeti

270 These findings provide impetus to the development of structurally diverse, next

271 f sentinel-lymph-node biopsy has brought new impetus to the early staging of cancer in general, and b

272 This has provided the impetus to the establishment of large-scale mutagenesis

273 These results lend impetus to the further development and broader implement

274 antibodies (bNAbs) has provided an enormous impetus to the HIV vaccine research and to entire immuno

275 it or promote their activity has lent a huge impetus to the immunotherapy of melanoma.

276 s, and patient preferences provided addition impetus to the popularity of ambulatory surgery.

277 We anticipate this method to give great impetus to the practical improvement of ion-beam cancer

278 e traits" in chronic airways disease, adding impetus to their evaluation and management in difficult

279 Added impetus to this approach has been fostered by the recent

280 Genome and HapMap projects have added fresh impetus to this goal by cataloguing the raw genetic data

281 Thus, there is a major impetus to understand the regulation of AR action.

282 This adds further impetus to understanding compartmentalization of functio

283 plete sequencing experiment and provides the impetus to use ddPCR-based quantification for improvemen

284 lower enantioselectivity, which provided the impetus to use structure enantioselectivity correlations

285 lity of those agents has provided the strong impetus to utilize this novel class of materials to engi

286 lescent mental healthcare are giving renewed impetus to work in primary care.

287 Recently, new impetus, tools, and model systems have emerged to re-exa

288 This development has provided renewed impetus toward an HIV vaccine and led directly to the de

289 ivery for repair and regeneration is gaining impetus with our understanding of constructing tissue-li

290 atherosclerosis has recently received added impetus with the realization that apoptosis is probably