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1 These findings implicate actin dynamics as a means of tuning receptor s

2 Our results implicate adolescence as a developmental phase of increa

3 These findings implicate AIM1 as a key suppressor of invasive phenotype

4 These data implicate alpha-toxin as a relevant antigen in severe pe

5 Our findings implicate amphiregulin as a critical mediator of the est

6 Extensive studies in non-human animals implicate amygdala dysfunction as a critical substrate f

7 These newer findings further implicate anatomic compartmentalization as a generalized

8 TL7 expression in cancer cells; our findings implicate ANGPTL7 as a mediator of metastatic progressio

9 These findings implicate AP-4 as a regulator of autophagy and altered a

10 These data implicate aPKC as a novel regulator of energy and glucos

11 These results implicate AQP1 as a novel determinant in renal cyst deve

12 Our findings implicate autophagy as a novel therapeutic target for GR

13 ew of hematogenous dissemination of ZIKV and implicate AXL as a new target for antiviral therapy.

14 Our results implicate BDNF as a genetic risk factor for ADHD, potent

15 These findings implicate BM stiffening as a critical determinant of HG-

16 Taken together, these data implicate BPIFB6 as a key regulator of secretory pathway

17 mic brainstem pathways to hypoxic stress and implicate brainstem SD as a previously unrecognized site

18 These data implicate cAMP signaling as a critical regulator of geno

19 These results implicate CDK19 as a regulator of p53 stress responses a

20 These findings implicate CerS6 as a novel regulator of PLIN2 and sugges

21 These findings implicate cGAS as a key driver of autoimmune disease and

22 These findings implicate cholesterol imbalance as a contributor to immu

23 Our data implicate CK2 as a regulator of the Th17/Treg axis and T

24 Our findings implicate CYSLTR2 as a uveal melanoma oncogene and highl

25 Our studies implicate cytoplasmic dynein as a more thermally tunable

26 een IAV replication and RIPK3 activation and implicate DAI as a sensor of RNA viruses.

27 Overall, our studies implicate Drp-1 as a potential therapeutic target agains

28 ome-based trafficking pathways in atria, and implicate EHD3 as a key player in the regulation of atri

29 Together our findings implicate eIF5A as a cytoskeletal rheostat controlling R

30 These findings implicate En1 as a newly identified and reciprocal deter

31 Our findings implicate epithelial DUOX1 as a pivotal mediator of IL-3

32 Together, these studies implicate ERK as a specific effector of Vegfa signaling

33 Together, these data implicate FES as a driver of melanoma progression and de

34 These data implicate FGF2 as a major factor VAT releases to transfo

35 These results may implicate FOXC1 as a new important regulator of mammary

36 These findings implicate FzlA as a critical coordinator of envelope con

37 tiating cytokine in cardiac inflammation and implicate GM-CSF as a potential target for therapeutic i

38 The results implicate GPC6 as a novel determinant of BMD, and also i

39 Together, these results implicate Gpr182 as a negative regulator of intestinal M

40 These observations implicate H1 as a critical factor in the formation of un

41 Our findings implicate Hh signaling as a key component of the network

42 Overall our results implicate homodimeric KIF3CC as a unique promoter of mic

43 building on several recent publications that implicate IgM as a crucial molecule that determines both

44 inflammation and cholesterol homeostasis and implicate IL-19 as a link between inflammation and macro

45 Instead, our findings implicate intron mobility as a direct driver of host gen

46 at IQGAP1 is a scaffold for IR and IRS-1 and implicate IQGAP1 as a participant in insulin signaling.

47 Taken together, our data implicate Irk channels as a requirement for regulated re

48 sults identify IRX1 as a prometastatic gene, implicate IRX1 hypomethylation as a potential molecular

49 votal role for BAZ1B in neurodevelopment and implicate its haploinsufficiency as a likely contributor

50 9a as novel enhancer-associated factors, and implicate Jmjd2c as a molecular scaffold for the assembl

51 Our findings implicate kirenol as a useful agent for the treatment of

52 The results of these studies implicate mGlu3 as a major regulator of PFC function and

53 These data implicate miR-155 as a potential therapeutic target for

54 atures of Brown-Vialetto-Van Laere syndrome, implicate mitochondrial dysfunction as a downstream cons

55 Together, our data implicate MNK1 as a key component of BDNF-mediated trans

56 Our findings implicate mTORC2 signaling as a novel pathway regulating

57 Our findings implicate Munc18c as a regulator of Stx4-mediated traffi

58 In aggregate, our findings implicate MYLK as a gene involved in the recessive form

59 nding of p53 regulation in hematopoiesis and implicate MYSM1 as a potential p53 cofactor.

60 ature of non-neural manifestations of HD and implicate NO depletion as a key mechanism underlying the

61 l anomalies that include cardiac defects and implicate NOTCH1 haploinsufficiency as a likely molecula

62 B or PDGF receptor-beta cell interactions to implicate PDGF-BB as a primary effector of MM cell vascu

63 of bats as an evolutionary origin for PEDV, implicate PEDV as a potential threat to other species, a

64 These novel findings implicate plasma PK as a risk factor for vascular diseas

65 These studies implicate RAC1 as a potential therapeutic target for pso

66 Our results implicate Rai1 as a novel and central player in processi

67 in population in BRCA1-mutation carriers and implicate RANKL blockade as a promising strategy in the

68 in the restriction of viral pathogenesis and implicate RIPK3 as a key coordinator of immune responses

69 Our results implicate S6K1 dysregulation as a previously unidentifie

70 Our results implicate SET-4 as a sensory rheostat that reinforces de

71 ity characteristic of Slc7a10-null mice, and implicate SLC7A10 as a candidate gene and auto-antibody

72 pathology with impaired NREM SWA, these data implicate sleep disruption as a mechanistic pathway thro

73 These findings implicate SLPI as a potential biomarker of resistance to

74 Our data implicate SOCS-3 as a critical negative regulator of alv

75 These results implicate SPOP as a novel participant in DSB repair, sug

76 Taken together, these findings implicate STAT2 as a novel regulator of DRP1 phosphoryla

77 Our findings implicate substrate flexibility as a critical determinan

78 isoform selectivity, and bound phospholipids implicate the membrane as a modulator of channel functio

79 Recent findings implicate the microbiome as a driver of this systemic im

80 how p97 maintains lysosomal homeostasis, and implicate the pathway as a modulator of degenerative dis

81 as potent regulators of ILC2 activation and implicate their utility as a therapeutic approach for th

82 ells have SOCE mediated by CRAC channels and implicate them as a mechanism for Ca(2+) uptake in ename

83 Collectively, these data implicate thrombinuria as a contributor to podocyte inju

84 hemical, mechanistic, and human studies that implicate Tie2 as a critical switch.

85 innate receptors in metabolic disorders and implicate TLR3 as a key control system in metabolic regu

86 t determinant of VLDL metabolism and further implicate TM6SF2 as a causative gene underlying metaboli

87 These results implicate TMS as a promising approach for reversing the

88 These results implicate TNFAIP3 as a functionally important endogenous

89 Our findings implicate TOP2A cleavage as a broad DNA damage mechanism

90 role of TSPO in CNS disease, and our results implicate TSPO as a potential therapeutic target in MS.

91 These results implicate unphosphorylated PtsN as a negative regulator

92 d to fibrosis development from Sav1 loss and implicate VP as a potential pharmacological inhibitor to

93 Taken together, these findings implicate WigKR as a regulator of cell wall synthesis th

94 Altogether, these data implicate YAP1 as a fluid mechanosensor that functions t

95 These findings implicate ZEB1 as a stem cell regulator in glioma which

96 Our data implicate ZnT2 as a critical mediator of cell death duri

97 Structural analysis implicated Arg511 as a required residue for Rab-GAP func

98 identified downstream effector pathways, and implicated ATDC as a candidate biomarker and therapeutic

99 Recent animal and human studies have implicated dietary sodium as a risk factor in MS, whereb

100 Finally, genetic interaction studies implicated Drp1 as a partner in Actr10-dependent mitocho

101 rofiling of C3-deficient cultured astrocytes implicated EGFR signaling as a hub in C3-dependent respo

102 Several recent studies have implicated ETS1 as a critical driver of immune cell func

103 pecific gene encoding an RNA-binding protein implicated in translation, as a crucial target of NANOS2

104 cell proliferation and recent findings have implicated its role as a tumor suppressor.

105 ecifically in CD11c-expressing cells in vivo implicated macrophages as a critical innate immune contr

106 ranscriptome data from CDCexo-primed Mvarphi implicated miR-181b as a significant (P=1.3x10(-21)) can

107 Further investigation implicated p53 as a transcription factor involved in reg

108 A growing number of recent reports have implicated Rickettsia felis as a human pathogen, paralle

109 affecting different liver-related traits and implicated Sel1l as a significant determinant of serum b

110 Finally, our study implicated ultraviolet radiation as a major factor in bo

111 The results clearly implicated VEGF as a major contributor to DME and have b

112 This study therefore implicates c-Myc as a potential regulator of the cancer-

113 Emerging evidence implicates circadian abnormalities as a component of the

114 More importantly, this study implicates Col18a1/ES as a potential new therapeutic tar

115 lular genes important for cell viability and implicates EBNA1 as a critical regulator of transcriptio

116 erance may be an important root defense, and implicates GA as a signal component of inducible plant t

117 to determine T cell responses to hypoxia and implicates GAPDH as a potential mechanism for controllin

118 This finding implicates Gpr124 as a potential therapeutic target for

119 astatic phenotype in ER(+) breast cancer and implicates IKKbeta as a driver of certain features of ag

120 Ipo11 mutant mice develop lung tumors, also implicates Importin-11 as a novel tumor suppressor.

121 ng targeted depletion of JARID1B(high) cells implicates it as a candidate therapeutic target within t

122 hts into the biological roles of GPC SSP and implicates it as a good target for the development of an

123 ient selection and treatment evaluation, and implicates LINC00473 as a therapeutic target for LKB1-in

124 and exposes a gene expression signature that implicates MAC as a driver of tumor progression.

125 Epidemiological evidence implicates maternal infection as a risk factor for autis

126 pregnancy complications, increasing evidence implicates maternal obesity as a major determinant of of

127 her with the finding of genetic loss in CRPC implicates PLZF inactivation as a mechanism promoting AD

128 This study implicates pretreatment MVD as a potential predictive bi

129 hanism for regulating tankyrase activity and implicates PrxII as a targetable antioxidant enzyme in A

130 rces are distributed over memory targets and implicates selective attention as a main gating mechanis

131 erically activates a cognate DUB partner and implicates super dimerization as a new regulatory mechan

132 ring is achieved is unknown; recent evidence implicates swallowing inhibition as a potential factor.

133 se a unique heme biosynthesis pathway, which implicates this pathway as a target for development of a

134 ism for activation of V. cholerae H-NOX that implicates this protein as a dual redox/NO sensor.

135 stinct neurobiology for this ion channel and implicates TRPV4 as a novel therapeutic target for neuro

136 ariability of tDCS-induced effects, not only implicating age as a crucial modulating factor, but deta

137 cholesterol metabolism and Notch signaling, implicating AIBP as a possible druggable target to modul

138 lay an important role for its activity, thus implicating arginine methylation as a novel regulatory m

139 uencing localized PDX1 to the Atf5 promoter, implicating Atf5 as a PDX1 target.

140 1 are within a potentially druggable pocket, implicating Bag-1L as a potential therapeutic target in

141 nduce significant hypomyelination pathology, implicating c-Jun as a potential player in demyelinating

142 rioles does not affect Fz/PCP establishment, implicating centriolar positioning as a conserved PCP-re

143 sease-associated genetic polymorphisms, thus implicating CEV as a biomarker of aging and disease susc

144 roved renal health in diverse models of CKD, implicating dynamin as a potential therapeutic target fo

145 and from multiple other clinical data sets, implicating FAO as a dysregulated pathway that is critic

146 eased both cyclin B1 protein and RNA levels, implicating FoxM1 as a critical target for cyclin B1 inh

147 xpression of both cyclin B1 protein and RNA, implicating FoxM1 as a critical target mediating MVM-ind

148 individuals is very low (p = 7.1 x 10(-21)), implicating GNB1 as a genome-wide-significant disease-as

149 utations are predominantly loss-of-function, implicating haploinsufficiency as a frequent mechanism.

150 n effect ameliorated by HIF-2alpha deletion, implicating HIF-2alpha as a biomarker for Vorinostat eff

151 ated at both the gene and the plasma levels, implicating IFN induction as a factor in elevated BAFF l

152 rological outcomes in lentiviral infections, implicating insulin as a therapeutic intervention for HA

153 o modulate Th9 cell differentiation, thereby implicating IRF8 as a potential therapeutic target to af

154 be improved via inhibition of HDAC6, further implicating it as a potential therapeutic target for CF.

155 so reduces IL-9 expression by human T cells, implicating ITK as a key regulator of Th9 induction.

156 A methyltransferase inhibition, specifically implicating KRAS status as a biomarker of drug response

157 and reduced antitranscriptional activities, implicating M as a primary regulator of cytopathicity an

158 duced interval Bbaa1 congenic mice, formally implicating myostatin as a novel downstream mediator of

159 tically deleted or mutated in human cancers, implicating NFkappaB2 as a potential tumor suppressor.

160 nfiltration into the tumor microenvironment, implicating NSD1 as a tumor cell-intrinsic driver of an

161 d glucose uptake in skeletal muscle cells by implicating p41ARC as a new component of the insulin-sig

162 , and genetic inhibition of endothelial NOS, implicating peroxynitrous acid as a key damaging agent.

163 familial form of Alzheimer's disease (AD) by implicating PrP(C) as a potential therapeutic target for

164 equired for persistent PrP(res) propagation, implicating raft microdomains as a location for conversi

165 ns precursor cells forming the lens vesicle, implicating Snf2h as a key regulator of lens vesicle pol

166 gistic growth inhibition of MDA-MB453 cells, implicating Src as a mediator of resistance to HER2-targ

167 with that seen in localized tumors, further implicating SRC-2 as a prominent metabolic coordinator o

168 wer hydrolyzing capacity in the same assays, implicating tau as a proteotoxin.

169 tem cell (HSC) self-renewal/differentiation, implicating TET2 as a master regulator of normal and mal

170 Evidence has accumulated implicating the amygdala as a critical structure in medi

171 e decision making; and add to the literature implicating the insula as a key brain region in addictio

172 indin is capable of binding riboflavin, thus implicating the protein as a metabolite carrier between

173 in linkage disequilibrium with nearby SNPs, implicating these variants as a source of novel genetic

174 subjects recognized distinct IGRP peptides, implicating this molecule as a trigger for CD4(+) T cell

175 expression of TUSC5 had the opposite effect, implicating TUSC5 as a positive regulator of insulin-sti

176 aphic rule-formulated for animals-to plants, implicating UV as a selective agent on a floral trait ge

177 erlie ageing- and obesity-associated IR, and implicate fTreg cells as adipo-immune drivers and potent

178 g of ILCs and the diseases in which ILCs are implicated, such as allergic inflammation.

179 These results implicate AURKA as an effective biomarker for bladder ca

180 Collectively, these observations implicate cGAS as an important cytosolic sensor of P. fa

181 Taken together, these results implicate Charon as an essential mediator of PARP-1-depe

182 These observations therefore implicate CREBBP mutation as an early event in FL evolut

183 Here, we implicate endogenous bioelectricity as an instructive fa

184 These data implicate FGF14 as an organizer of channel localization

185 These results implicate HDAC1 as an important mediator of tissue damag

186 The results implicate IL-1 as an important driver of neonatal morbid

187 These data implicate Jarid2 as an important component of PRC2 that

188 These findings implicate M. genitalium as an etiologic agent of cervici

189 In conclusion, our data implicate PDDCs as an important target for resolution of

190 Collectively, these studies implicate peroxide tone as an important mechanistic comp

191 Our results implicate pO2 as an important factor in climate forcing

192 death from loss of CRADD function in humans implicate reduced apoptosis as an important pathophysiol

193 Taken together, these data implicate RGS6 as an essential regulator of DA bioavaila

194 with the apical plasma membrane and further implicate sumoylation as an important mediator of protei

195 These findings implicate Tau as an essential mediator of the adverse ef

196 Our findings therefore implicate the preIC as an additional protein complex inv

197 These findings implicate TWIST1 as an important factor regulating OA re

198 3 expression, whereas functional predictions implicated ABLIM1 as an allele-specific expressed gene i

199 the length of the bridging linker, which has implicated membrane interactions as an essential feature

200 Previous work implicated Soj as an important regulator of oriC positio

201 X-derived ROS and macrophage phenotypes, and implicated superoxide as an important factor in macropha

202 More recent studies have implicated TEP as an active agent in biofilm formation a

203 Recent studies have implicated the spleen as an anatomic site for integratio

204 These results implicated YAP1 R331W as an allele predisposed for lung

205 central role in silencing HbF in humans and implicates BCL11A as an important factor for neurodevelo

206 The present study implicates MRP14 as an essential propagator of inflammat

207 ata to better understand prior research that implicates pharmaceutical promotions as an important fac

208 Recent evidence implicates S. aureus as an emerging cause of chorioamnio

209 , but not in non-small cell lung cancer, and implicates SPAG5 as an alternative cancer vaccine target

210 They review evidence implicating atrial cardiomyopathy as an independent cont

211 protein beta (C/EBPbeta) in various tumors, implicating C/EBPbeta as an interesting target for the d

212 ides a simple model for tissue regeneration, implicating cellular reprogramming as an essential eleme

213 helium and apoptosis in the allergic airway, implicating DSBs as an underlying driver of asthma patho

214 a12 upregulation in liver tumor progression, implicating Galpha12 as an attractive therapeutic target

215 However, recent evidence also implicated IL-17 as being involved in acute corneal allo

216 f disorders in which these systems have been implicated, such as bipolar disorder.

217 Synaptotagmin-7 has been implicated recently as Ca(2+) sensor in mediating delaye

218 ty in diseases where these viruses have been implicated, such as cancer and neurological syndromes.

219 -induced senescence and validated previously implicated genes such as CDKN1A We developed an innovati

220 Several independent studies have implicated tau protein as central to Alzheimer's disease

221 thylated in Burkitt and follicular lymphomas implicated DNA methylation as cooperating with somatic m

222 ncephalomyelitis, a murine model of MS, thus implicating both homologs as copathogenic contributors.

223 Genetic analyses implicate both proteins as critical for repair of DNA br

224 These findings implicate Gli1(+) cells as critical adventitial progenit

225 These findings collectively implicate PDGFRs as critical mediators of breast cancer

226 erentiate and respond to parasite infection, implicating hemocytes as critical modulators of the late

227 hat predict outcomes in lung adenocarcinoma, implicating these subpopulations as critical determinant

228 lls, including at MTNR1B, where fine mapping implicated rs10830963 as driving T2D association.

229 ovel target genes of the regulatory network, implicating morphogenesis genes as early targets of DV p

230 ion, processing and protein binding and thus implicate U8 as essential in cerebral vascular homeostas

231 at rates far slower than those of previously implicated signals such as H2O2 and ATP, ruling out thes

232 restoration of the naive T cell compartment, implicating the thymus as having functional regenerative

233 Previous work has implicated JH as immunosuppressive [12, 13], and the mal

234 agnitude of arrestin-mediated signaling, and implicate these sequences as important determinants of f

235 e effect of anti-cholinergic drugs have long implicated these neurons as important for cognition and

236 ratinocytes in vitro and in vivo and further implicates PSMs as important contributors to pathogenesi

237 Astrocytes have been implicated in SMA as in in other neurodegenerative disor

238 in, ghrelin, and dopamine signaling pathways implicating them as integrators of central and periphera

239 roteins promotes inflammasome activation and implicate GBPs as key regulators of this process.

240 ty identified cancer-specific deviations and implicated HOX factors as key regulators of preleukemic

241 Emerging evidence implicates platelets as key mediators of venous thromboe

242 FHIT due to genomic rearrangements strongly implicates these genes as key drivers of PDAC, thus high

243 re dependent on antigen presentation by DCs, implicating DCs as key mediators of organ-specific immun

244 entify IL-21(+)CD4(+) T cells as pTfh cells, implicating them as key populations in the generation of

245 ne cluster, impede amyloid formation by PrP, implicating these residues as key structural modulators

246 n virulence factors of periodontal pathogens implicated proteinases as major determinants of remarkab

247 Deeper in the water column, our study implicates Thaumarchaeota as major producers of cobalami

248 actors and histone proteins in human cancer, implicating them as major mediators in the pathogenesis

249 elia as "hot spots" for tumor formation, and implicate cutaneous nerves as mediators of tumorigenesis

250 ulthood recapitulate the original phenotype, implicating local environment as mediators of microglial

251 ve transcriptional and metabolomics analyses implicate MYB15 as necessary for the defense-induced syn

252 These data implicate CDH2 mutations as novel genetic causes of ARVC

253 This species-specific attribute implicates algal remodelers as novel and keystone player

254 Several studies have implicated protein synthesis as one among several of its

255 Fluorescence spectroscopy implicates interprotein dityrosine as one of the dimeriz

256 Collectively, this work implicates rs1076560(T) as one possible risk factor for

257 These findings implicate TLR4 signaling as playing a critical role in t

258 t not cortical afferents onto these neurons, implicating the thalamus as playing a key role in Parkin

259 prunae transcriptome during 'uranium-shock' implicated VapC toxins as possible causative agents of t

260 es in examination of panic disorder (PD) has implicated several variants as potential susceptibility

261 drug atorvastatin ameliorated the pathology, implicating statins as potential therapeutics against a

262 While some studies have also implicated miRNAs as regulators of the antiviral respons

263 Pathways analyses of microarray datasets implicate DNA methylation as significantly associated wi

264 In conclusion, CSCs were rich in human CCAs, implicating CCAs as stem cell-based diseases.

265 plication of this strategy to human lymphoma implicates immunoglobulin neoantigens as targets for lym

266 These results implicate ADAR1 p150 as the major A-to-I editor in mouse

267 Together these results strongly implicate declining mobility as the specific behavioral

268 These data further implicate GC TFH as the major HIV-1-producing cells in c

269 Collectively, our results implicate gluconeogenesis as the key mechanism behind or

270 These findings rule out climate change, and implicate humans, as the primary extinction cause.

271 ved differences in catalytic efficiency that implicate kinetics as the determinant for species-specif

272 and near-isogenic Htg9.1 genotypes strongly implicate LsERF1 as the gene responsible for the Htg9.1

273 ive assay for pff uptake in primary neurons, implicate lysosomal processing as the major fate of inte

274 Our findings implicate MYC deregulation as the underlying cause of th

275 These results implicate SpGAI as the feminizing factor in spinach, and

276 Mutation patterns strongly implicate ultraviolet radiation as the dominant mutagen,

277 trations or BT composition within all events implicate vehicle fluids as the key source of BTs in bot

278 Previous indirect evidence implicated APOBEC3B as the more likely major mutator dea

279 RNA-seq mutation data implicated CRAF R391W as the alternative driver mutation

280 IgG transfer in IgG-deficient mice implicated IgG as the pathogenetic ligand for endothelia

281 This investigation implicated raw flour as the source of an outbreak of STE

282 in AECs and neutralization of PGE2 in AEC-CM implicated this prostanoid as the major AEC-derived fact

283 This result specifically implicates aerobic nitrification as the dominant NO3(-)

284 uld be pivotal in engendering resistance and implicates chloroplasts as the primary sites driving gly

285 The dual oscillator model (DOM) implicates glycolysis as the source of oscillatory metab

286 Nevertheless, this study implicates IC2 as the critical zone of the IC for normal

287 CXCL9 expression in lesional macrophages implicates the skin as the source of circulating cytokin

288 ke discharges was not seen in the alpha4-/-, implicating alpha4betadelta GABARs as the cause of the d

289 osylbenzene could also produce mycocyclosin, implicating compound I as the initial oxidizing species.

290 n and liver of red factor canaries, strongly implicating CYP2J19 as the ketolase that mediates red co

291 blockers UCL 1684 + TRAM 34 attenuated ROV, implicating endothelial hyperpolarization as the underly

292 cking SKCa and IKCa channels attenuated ROV, implicating hyperpolarization as the underlying signal.

293 itic cells did not alter fungal burden, thus implicating Mvarphis as the pivotal cell in host resista

294 membrane penetration-competent SV40, further implicating this structure as the membrane penetration s

295 The variants associated with both outcomes implicate new pathways as well as targets of existing dr

296 f long-term memory and define general memory-implicated genes as well as conditioning-type-dependent

297 A plethora of splice variants have been implicated in CKDs as well.

298 CS) produced in living systems that has been implicated in epigenetics as well as in the pathologies

299 ance of proper brain circuitry, and has been implicated in neurodevelopmental as well as neurodegener

300 gnaling 2 gene (RGS2) in the mother has been implicated in preeclampsia as well as in the development