ライフサイエンスコーパス: implications for

1 ered mechanism for Ca(2+) mobilization by beta2AR has broad implications for adrenergic signaling, cross-talk with other

2 etic nerves in generating the acinar lineage that has broad implications for epithelial morphogenesis.

3 ation in the classic GPCR ternary-complex model, with broad implications for the multiplicity inherent in signaling netwo

4 miss clinically actionable genetic changes with established implications for cancer screening or prevention.

5 so illustrate spatiotemporal variations of MEFs and explore implications for energy storage technologies.

6 The genome conservation observed also has implications for the potential success of a therapeutic vacci

7 These findings have implications for the choice of device therapy in patients wit

8 These findings have implications for the development of selective allosteric modu

9 These findings have implications for understanding the causes and consequences of

10 etween phenotypic complexity and evolvability that may have implications for biological evolution.

11 These results have implications for the pancancer use of targeted drugs and pote

12 es of oxides and related emergent functionalities that have implications for device applications.

13 effective immune defence is species specific, and they have implications for understanding the pattern of Bd population g

14 nization of functional regions within genomes has important implications for evolutionary potential.

15 ation and when 'phenotype specificity' occurs has important implications for exercise prescription.

16 l for the homeostasis of primary cilia, which has important implications for human disorders related to primary cilia dys

17 cise understanding of these layers of control has important implications for organismal health and could offer new therap

18 It also has important implications for the design of lifespan experiments as autoto

19 e total expression of labelled protein, which has important implications for the development of future PALM tags.

20 Our findings have important implications for antibiotic stewardship and public health pol

21 erstitial tissue, confirmed in patients, may have important implications for biotherapies such as vaccines and monoclonal

22 Our findings have important implications for fundamental understanding of RVFV virulence.

23 ce of sequence context for alt-EJ repair and have important implications for genome editing and genome evolution.

24 ole" for the default mode network, which may have important implications for our current understanding of healthy and ada

25 es identified through integrative clustering have important implications for stratification of future clinical trials.

26 Our findings have important implications for the design of maternal vaccination strategie

27 Our findings have important implications for the understanding of compartmentalized cAMP

28 Our findings have important implications for the use of Adelie penguins in Southern Ocean

29 measure utility in a context-free manner and have important implications for theories of reinforcement learning and delay

30 skull and thus brain shrinkage and regrowth, with important implications for understanding adaptations to changing enviro

31 ying mechanism of this conformational rearrangement and its implications for heme transfer via site-directed mutagenesis,

32 tion of carbapenem resistance in Escherichia coli has major implications for the management of common infections.

33 mportant crossroad for APP and these secretases, with major implications for APP processing and amyloidogenesis.

34 The unusual envelope found in AFV1 also has many implications for biotechnology, since this membrane can survi

35 f the CSN in regulating EGFR neddylation has broad-reaching implications for understanding how homeostasis is achieved in

36 as atmospheric CO2 concentrations rise, having global-scale implications for water balance, carbon storage, and related r

37 d microbial community composition, and may have significant implications for CO2 losses from tropical forest soils under

38 Therefore, changes in these sources could have significant implications for global warming.

39 This educational gap can have significant implications for patients' safety.

40 nes are specifically affected by early malnutrition and the implications for males and females respectively.

41 Finally, we consider the implications for rational drug development, in particular reg

42 Here, I review these accounts and discuss their implications for understanding how predictions of the sensory

43 ic dissemination, with potential prognostic and therapeutic implications for metastasis by cancers that preferentially ex

44 common or rare genetic variation with potential therapeutic implications for T2D, we analyzed and replicated genome-wide

45 the integrative theory of numerical development along with implications for understanding mathematics disabilities.

46 ochastic gene expression and transcriptional bursting, with implications for regulation of pluripotency and development.P

47 These studies reveal hotspots for sequence evolution with implications for targeting and secondary structure.

48 or pairing by mediating homolog spatial juxtaposition, with implications for crossover (CO) patterning/interference.

49 isms can be optimized by manipulating Ag presentation, with implications for vaccine design.

50 Here we report evidence challenging this view, with implications for therapeutically targeting Mdm2.