1 Very
importantly,
11 and 12 were non-toxic with very safety a
2 Most
importantly,
16 showed memory-enhancing properties and i
3 Importantly,
a competition-based approach to specificall
4 Importantly,
a critical analysis of speeds of sound in I
5 Importantly,
a helix-disrupting mutation of W50R into re
6 Importantly,
a monoclonal anti-TIM-4 Ab promoted allogra
7 Importantly,
a second RRM domain (RRM2) of RBM10 recogni
8 Importantly,
acoustic interactions between multiple male
9 Importantly,
activated AKT directly phosphorylates FAF1
10 Importantly,
adoptive transfer of ILC2s restored eosinop
11 Importantly,
after a primary NPHV infection, horses were
12 bly or polarity of secretion of C1QTNF5 and,
importantly,
all appear to destabilise the wildtype prot
13 Importantly,
all patients investigated thus far have bee
14 neurons across multiple local circuits and,
importantly,
allow stable tracking of the evolution of t
15 specificity of the m.3243A > G mutation, and
importantly,
allow the future testing of novel therapeut
16 only their magnitudes, but more notably and
importantly also the spatial orientation of their princi
17 e achieve not only a site-specific but, most
importantly,
also a site-selective, label scheme that pe
18 relevant impact-compression SCI in rats, and
importantly,
also in the injured human spinal cord.
19 Importantly,
altering the intracellular zinc concentrati
20 Importantly,
although catalytic activity was essential f
21 Importantly,
and contrary to what is perceived for soft
22 Importantly,
and in contrast to (177)Lu-DOTATATE, inject
23 Importantly as metabolites differentiated genotype, geno
24 Importantly,
as in wild-type neurons, the repaired MeCP2
25 of alanine enantiomers is examined and, more
importantly,
AuNPs-embedded paper-based lab-in-a-syringe
26 Importantly,
avibactam, but not the bicyclic boronate is
27 Importantly,
AZD4547 impaired stem cell-like characteris
28 Importantly,
beta activity is not continuously elevated,
29 Importantly,
beta1 integrins containing an extracellular
30 slet function, e.g., PDX1, TCF7L2, and ADCY5
Importantly,
binding sites previously identified by ChIP
31 Importantly,
biomass temporal stability is not influence
32 Importantly,
blocking Kir channels also inhibits flow-in
33 Attenuating Sting, phosphorylated Tbk1 and,
importantly,
blocking reverse transcriptase activity sup
34 Importantly,
both behavioral defects and structural chan
35 Importantly,
both GEF changes are expected to decrease n
36 Importantly,
BPN delivery across the intact BBB, just be
37 Importantly,
BRCA2 overexpression partially restores the
38 Importantly,
breast cancer patients whose tumors express
39 Importantly,
calcipotriol plus 5-FU treatment induced TS
40 Importantly,
cassette activation leads to loss of gene e
41 Importantly,
CD4(+) T cell responses in vaccinees were s
42 Importantly,
changes in synaptic properties appear to be
43 Importantly,
collagen cross-linking requires fibronectin
44 Importantly,
combining existing pharmacogenomic markers
45 Importantly,
compressive temporal summation directly par
46 Importantly,
control principles also allow us to investi
47 this study collectively indicate that malate
importantly controls the chloroplast reductive status an
48 More
importantly,
CRIg stabilized the expression of Foxp3 in
49 Importantly,
DAPF showed stiffness properties that are w
50 yrogallol as value-added chemicals, and more
importantly demonstrates benign methods for valorization
51 rding R. typhi biology in flea vectors that,
importantly,
do not suffer lethality due to R. typhi inf
52 Importantly,
dose adjustments for tacrolimus were necess
53 Importantly,
dual inhibition of CK1alpha and the proteas
54 Importantly,
dual-labeled ribosome-nascent chain librari
55 Importantly,
each cell's correlation between activity an
56 Importantly,
EM2 and glutamate-containing varicosities a
57 Importantly,
embryonic deletion of the same gene in astr
58 Importantly,
endo-beta-galactosidase coupled with MALDI-
59 Importantly,
endogenous TH is required during this trans
60 Importantly,
ERI was able to detect many disease relevan
61 Importantly,
evoked neural activities were modeled by Ba
62 Importantly,
exogenous superoxide addition to CB3-infect
63 Most
importantly,
experimental increase in intracellular calc
64 Importantly,
expression analysis revealed that both SNHG
65 Importantly,
expression of degradation-resistant EXO1 re
66 Importantly,
expression of the GluA1 ubiquitin-deficient
67 Importantly,
false-positive rates were not affected by s
68 Importantly,
FcepsilonRII-mediated signaling by allergen
69 More
importantly,
Fe3 Mo3 C is very active for oxygen reducti
70 Importantly,
following a high-fat challenge, carriers in
71 olled for preoperative risk factors and most
importantly for the surgical procedure performed, demons
72 Importantly,
FOXA1 is downregulated in human NEPC tumors
73 Importantly,
genetic factors operating at 8 years explai
74 Importantly,
GRHL2 maintained AR expression in multiple
75 Importantly,
hand motor output and hand dexterity increa
76 Importantly,
HDM-induced DNA damage can be prevented by
77 Importantly,
hepatocyte-specific overexpression of beta-
78 Importantly,
hierarchical clustering demonstrated an ass
79 Importantly,
high CAMKIIgamma levels in patient TCL spec
80 Importantly,
higher cross-reactive haemagglutination-inh
81 Importantly,
HL2-m5 is able to effectively suppress Shh-
82 More
importantly,
however, studies of keratin have seeded the
83 Importantly,
however, the fratricide conferred by SLAMF7
84 derepression of its well-known target, Etv4
Importantly,
human T-ALL also relies on ETV4 expression
85 Importantly,
hVLPs also showed superior activation of En
86 oborate the presence of MWW layers and, more
importantly,
identify two distinct types of Q(3) silanol
87 t for inducing multisensory integration, and
importantly,
if biomechanical constraints encoded in the
88 Importantly,
IFN-gamma exposure during activation reduce
89 d subsequently Dlg4/PSD95 expression, which,
importantly,
impacted several hippocampal neuron plastic
90 ld be assessed using various models and more
importantly,
in a model mimicking conditions of its clin
91 Most
importantly,
in addition to positive triple junction for
92 ase (AD) mouse models (3xTg and Tg2576) and,
importantly,
in cryopreserved human AD brain samples.
93 Importantly,
in mosquito-infected animals ZIKV tissue di
94 Importantly,
in silico modeling validated that this Ser-
95 Importantly,
in vivo analyses of the homologs of RBPJ an
96 el method that predicts accessible and, more
importantly,
inaccessible gene-regulatory chromatin regi
97 Importantly,
infusion of the nitric oxide synthase inhib
98 Importantly,
insulin prevented the AbetaO-induced inhibi
99 Importantly,
intestinal bile acid sequestration with cho
100 Importantly,
Ip3r2-deficient mice displayed a reduction
101 Importantly,
isosmotic cell swelling obtained by paralle
102 Importantly,
it allows the peroxo-diferric intermediate
103 Importantly,
it further confirms the role of CD14+ monoc
104 aphic and environmental gradients, and, more
importantly,
it includes rear-edges of the continuous di
105 Importantly,
it is also demonstrated that E. coli bacter
106 Importantly,
it reveals that initial high viral load and
107 More
importantly,
it would increase the persistence time for
108 Importantly,
local injection of anti-DC-STAMP-mAb also s
109 Importantly,
localized microinjection of PMN-MPs into wo
110 Importantly,
loss of appetitive behavioral responses to
111 Importantly,
low-fitness neoantigens identified by our m
112 Importantly,
MAJIQ-SPEL is able to handle both classical
113 Importantly,
median predicted rank of catalytic residues
114 Importantly,
MEK1 activity was necessary to clear the pl
115 Importantly,
metabolites consistent with chronic inflamm
116 Most
importantly,
MHIRE has been demonstrated to significantl
117 Importantly,
MiP myogenic propensity is influenced by so
118 Importantly,
Modern and Historical patterns of resource
119 Importantly,
naturally acquired antibodies against the r
120 Importantly,
neurobehavioral deficits, E/I imbalance, an
121 Importantly,
neuronal loss was attenuated by 44% in the
122 Importantly,
NMDAR-mediated signaling was observed in ra
123 functionally or at the molecular level, and
importantly no aberrant protein expression.
124 Importantly,
no sequences corresponding to novel viruses
125 Importantly,
noneditable versions of reviewed FS can be
126 Importantly,
not only did suppressed alpha power and bot
127 Importantly,
NOX4 gene deletions are frequent in HCC pat
128 Importantly,
NPC-derived daughter cells appeared to be l
129 Importantly,
NPM-ALK is capable of transforming primary
130 Importantly,
Nrf2 activation significantly reduced react
131 Importantly,
NTS(HSD2) neurons stimulate appetite via pr
132 Importantly off-pathway oligomers saturate within a limi
133 Importantly,
one of these sites broadly overlaps with th
134 Most
importantly,
oral administration of KPT-9274 reduces tum
135 Importantly,
OTUD1 is lost in multiple types of human ca
136 Most
importantly our results indicate that the effects of man
137 Importantly,
our analyses suggest that stress-induced tr
138 Importantly,
our combinatorial therapy resulted in tumor
139 Importantly,
our complementary in vivo studies demonstra
140 Importantly,
our findings allow us to interpret the func
141 Importantly,
our findings show that sRNAs across bacteri
142 Most
importantly,
our model reveals that mixed halide perovsk
143 Importantly,
our study revealed that S1P1 not only regul
144 But perhaps more
importantly,
our study reveals the potential for empiric
145 Importantly,
PDX-derived ellipsoids in microchambers ret
146 Most
importantly,
PEDOT-C14-based SC pH sensors have no CO2 i
147 Importantly,
Pfn2-deficient mice showed iron accumulatio
148 Importantly,
pharmacological or genetic ablation of inne
149 Importantly,
phosphorylation of LARP1 by mTORC1 and Akt/
150 Importantly,
Pre-F-GCN4t was also shown to bind D25, a h
151 Importantly,
preventing the cross talk by preceding DC d
152 Importantly,
prominent mucosal immune responses in CCR7-
153 Importantly,
prospective studies evaluating whether scre
154 Importantly,
Raman spectroscopy revealed molecular-level
155 Importantly,
recent discoveries are paving the way to th
156 Importantly,
recent evidence shows that having an 'older
157 the site of action appear possible, and most
importantly,
recognition of encapsulated allergen by the
158 ng, provide low off-target toxicity and most
importantly reduce FTY720-induced lymphopenia, suggestin
159 The wheal size in SPT was
importantly reduced after application of thermally-treat
160 Most
importantly,
residues 258-269 of securin are located in
161 nism for Rac1 activation in tumors and, most
importantly,
reveal that activation of Rac1 is an uniden
162 Finally and most
importantly,
ribavirin treatment in vivo significantly e
163 Importantly,
secretion of wild-type human SOD1 and the A
164 More
importantly,
selective inhibition of the extracellular H
165 Importantly,
selinexor decreased AXL and GAS6 levels in
166 Importantly,
sequestration inside the DNA capsule preven
167 Importantly,
silencing AL L5 feedback reduced visual res
168 Importantly,
simultaneous patients had more renal vascul
169 Importantly,
SL1 and SLC are functionally interchangeabl
170 nt activation of Vgamma9Vdelta2 T cells and,
importantly,
strongly reduced the production of inflamma
171 Importantly,
studies focused on geographic and cultural
172 Importantly,
such a mechanotransduction-mediated phenoty
173 Importantly,
such positive feedback can drive large fluc
174 Importantly,
suppression of GABAergic transmission via D
175 ting compound activation, uptake, efflux and
importantly,
target processes.
176 Importantly,
targeted therapies blocking the aberrant ac
177 he differences in structural properties-most
importantly the linker distributions-and synthesis mecha
178 Importantly,
the abundance of alphaSyn oligomers in huma
179 Importantly,
the algorithm reported herein is hardware a
180 Most
importantly,
the association with rs715212 is noteworthy
181 Importantly,
the autophagy-inducing bioactivity was redu
182 Importantly,
the benefit of range adaptation outweighs t
183 Importantly,
the C1 (OE) rice plants grown on soil conta
184 Importantly,
the C3a treatment led to faster and more co
185 Importantly,
the caspase and the E3 ligase execute this
186 Importantly,
the combination of antibody CD19-DE and cyt
187 Most
importantly,
the computational ability to switch on and
188 Importantly,
the decrease in burst duration was also cor
189 Importantly,
the Delta346 mutant maintains similar antig
190 Importantly,
the ease with which spontaneous biological
191 Importantly,
the enhancement at low temperature are cons
192 Most
importantly,
the entire process could be quickly complet
193 Importantly,
the hybrids composed of Az and geldanamycin
194 Importantly,
the ICG-EPI NPs showed excellent tumor targ
195 More
importantly,
the intelligent artificial throat will sign
196 Importantly,
the mass-escalation study indicates that an
197 Importantly,
the mild synthetic routes to halide perovsk
198 Importantly,
the more complete phospho-Rb inhibition and
199 Importantly,
the mutant of Ser-176 and the previously re
200 Importantly,
the MzASMT9 gene was found to be upregulate
201 Importantly,
the omentum collects metastasizing tumor ce
202 Importantly,
the patient has shown remarkable motor, cog
203 More
importantly,
the phase transition yields a three orders
204 Importantly,
the PopP2-RRS1-RWRKY association is alloste
205 Importantly,
the proportion of EV-A71 infection generall
206 Importantly,
the recognition takes place in the denatura
207 Importantly,
the redistribution of intracellular LFA-1 a
208 Importantly,
the Seebeck coefficient agrees with recentl
209 Importantly,
the server presents a comprehensive workflo
210 Importantly,
the specific K:R ratio is likely to be impo
211 Importantly,
the study provides reference values of norm
212 Importantly,
the sufD* strain did not exhibit altered ex
213 Importantly,
the TLR4 pathway was activated constitutive
214 Importantly,
the two different photoactivatable groups d
215 Importantly,
the uptake of exosomes, derived from IL-2 s
216 More
importantly,
the utility of SELDOM goes beyond basic net
217 Importantly,
these animal models have not yet contribute
218 Importantly,
these connections are already being exploit
219 Importantly,
these data suggest that developmental plast
220 Importantly,
these dNTP imbalances are strongly mutageni
221 Importantly,
these effects of miR-140-5p are largely res
222 Importantly,
these FV(+) particles have the same size di
223 Importantly,
these lateralization effects were stronger
224 Importantly,
these primary atypical meningiomas do not h
225 Importantly,
these results indicate that the impact of s
226 Most
importantly,
these sensors offer low-cost and disposable
227 Importantly,
this bias was abolished by both electrolyti
228 Importantly,
this characterization is effective in predi
229 Importantly,
this conversion induces compensatory mechan
230 Importantly,
this DDX39B variant showed strong genetic a
231 Importantly,
this group of Nups is largely restricted to
232 Importantly,
this immunotherapeutic regimen was also cur
233 Importantly,
this mechanism of HR is independent of RAD5
234 Importantly,
this mutation was able to sustain 15% of wi
235 Importantly,
this nested factor structure provided bette
236 Importantly,
this phenomenon explains the aberrant expre
237 Importantly,
this reshaping includes the addition of new
238 Importantly,
this softening is contrary to TM stiffening
239 Importantly,
this was not due to impaired consolidation
240 Importantly,
this would have been impossible without int
241 Importantly,
three of the four modified tyrosines, some
242 Importantly,
three of these gradients were found to be n
243 Importantly,
through in vitro binding and activity assay
244 Importantly,
time-resolved photoconductivity measurement
245 hat has been accomplished by the Network and
importantly to identify the challenges and opportunities
246 environment in its binding pocket and, more
importantly,
to the conformation of its beta-rings.
247 Importantly,
TPE-TPP can detect the presence of prefibri
248 Importantly,
treatment of LRRK2 G2019S expressing midbra
249 Importantly,
treatment with either DAC or DAC+KDM5i indu
250 Importantly,
tumors with a luminal molecular subtype hav
251 Importantly,
uncertainty should not be reduced purely ba
252 r HDAC1 in PU.1 gene transcription and, more
importantly,
uncover a novel mechanism of TFIID recruitm
253 Importantly,
under certain conditions, the abundant HMW
254 Importantly,
unlike the canonical approach, an optimal e
255 Importantly,
upon purification and transfer of donor-der
256 Importantly,
using gene expression analysis (N = 60) and
257 onstrated by numerical simulations and, more
importantly,
validated quantitatively by single-cell dat
258 Importantly,
very high numbers of antigen-specific B cel
259 Importantly we show that TRAILshort is shed in microvesi
260 Importantly,
we additionally find that size reduction in
261 Importantly,
we also consider the development of strateg
262 Importantly,
we also demonstrate that a norovirus can in
263 Importantly,
we also find that none of these residues in
264 Importantly,
we defined the repertoire of pollen tube-se
265 More
importantly,
we demonstrate how the XCMS/METLIN platform
266 Importantly,
we demonstrate that combined use of MEK1/2
267 Importantly,
we demonstrate that trace exogenous chemica
268 Importantly,
we demonstrated how proteomics data could b
269 Importantly,
we demonstrated that the exogenous ToV-PLP
270 Importantly,
we discover that receptor tyrosine kinase A
271 Importantly,
we find that expression of AP2alpha, a gene
272 Importantly,
we find that HAstV-2 capsid spike containin
273 Importantly,
we find that ICP27-PABP forms a complex wit
274 Importantly,
we find that our open-channel model is cons
275 Importantly,
we find that the HIV-1 Vif-A3H interface is
276 Importantly,
we found that licensing of cytokine product
277 Importantly,
we found that tau knockdown reduced axon ou
278 Most
importantly,
we found that the loss of Ccr7 results in a
279 Importantly,
we found that these dispersers tended to in
280 Importantly,
we have corrected a previously identified e
281 Importantly,
we have found here that loss of PDHK4, a ke
282 Importantly,
we highlight disconnect between the epiderm
283 Importantly,
we identified chaperonin containing TCP1 su
284 ffer from those collected in vitro, and most
importantly,
we identify four UBPs whose retention in th
285 Importantly,
we observe the development of persistent an
286 Importantly,
we reveal a patient missense variant, L344P
287 Importantly,
we show for the first time that M. bovis ar
288 Importantly,
we show how the spatial and temporal effect
289 Importantly,
we show quantitatively with LC/MS analytics
290 Importantly,
we show that extended ion accumulation in c
291 Importantly,
we show that leukaemia cells transfected wi
292 Importantly,
we show that resetting, its neural marker,
293 Importantly,
we showed that CDK3, NFAT3 and phosphorylat
294 acterized how MCs contribute to disease and,
importantly,
what strategies may be used to target MCs a
295 Most
importantly,
when modulating the expression of hDBR1, wh
296 Importantly,
when the killing is measured before the ste
297 Importantly,
while the peptide brHis2 fails to transloca
298 Importantly,
while these ribosomal mutations have a fitn
299 Importantly,
whisker response amplitude is also modulate
300 Importantly with respect to empirical therapy with new b