ライフサイエンスコーパス: importer

1 ly protein Pic2 in budding yeast is a copper importer.

2 eat peptides to the surface of NTF2, the Ran importer.

3 ll indicating that Zip14 functions as a zinc importer.

4 c staphylococcal species do not possess this importer.

5 it is inferred that BldK is an oligopeptide importer.

6 48 are part of a previously unidentified DNA importer.

7 CC1, the gene that encodes the vacuolar iron importer.

8 et emission exporter to being a net emission importer.

9 siologically stimulates DMT1, the major iron importer.

10 at PlaP functioned as the primary putrescine importer.

11 e transport of small substrates by a Type II importer.

12 ption of CCC1, which encodes a vacuolar iron importer.

13 pression was mntH, which encodes a manganese importer.

14 cidental, occurring via some essential metal importer.

15 nd the plasma membrane acts as a cholesterol importer.

16 cription factors, alpha-tubulin, and nuclear importers.

17 the high-level expression of sulfur-compound importers.

18 S4, genes that encode the mitochondrial iron importers.

19 port mechanism between ABC exporters and ABC importers.

20 orter MalFGK(2) is a study prototype for ABC importers.

21 associated with elevated expression of zinc importers.

22 Type II importers accept substrates in a nucleotide-free state,

23 vation activates transcription of the biotin importer and simultaneously represses transcription of t

24 least partially dependent on the YfhA YfiYZ importer and the YusV ATPase.

25 ibactin and enterobactin requires the FeuABC importer and the YusV ATPase.

26 ajor ABC transporter folds, namely large ABC importers and ABC exporters.

27 porters it seems likely that the TMDs of ABC importers and exporters have evolved different mechanism

28 RIT-seq profiling identifies both known drug importers and the only known pro-drug activator, and lin

29 three proteins by inducing MntH, a manganese importer, and Dps, an iron-sequestration protein.

30 e, Abcb6 is the sole ATP-dependent porphyrin importer, and loss of Abcb6 produces up-regulation of he

31 n homeostasis genes, psaBCA, encoding the Mn importer, and mntE, encoding the Mn exporter, lead to Mn

32 ompensates for the loss of Msc2p, an ER zinc importer, and therefore helps to alleviate ER stress.

33 n differences in structure and activity, ABC importers are divided into two types.

34 Bacterial ATP-binding cassette (ABC) importers are primary active transporters that are criti

35 nd Extremadura, while the main virtual water importers are the industrialized regions of Madrid, Basq

36 eficiency, whereas the energy-dependent zinc importers are upregulated during severe zinc deficiency.

37 1, which activates the Ctr4 high affinity Cu importer, are hypo-virulent in mouse models.

38 MFe(hi) ATMs and the gene expression of iron importers as well as the iron exporter, ferroportin, sug

39 nctional traits with both type I and type II importers, as well as possessing unique features, and em

40 y, 89 countries analyzed were net blue water importers at the national level.

41 The auxin importer AUX1 functions as a positive regulator of cytok

42 been observed in studies of the vitamin B12 importer BtuC2D2.

43 richia coli vitamin B12 ATP-binding cassette importer BtuCD-F.

44 usly observed for the homologous vitamin B12 importer BtuCD.

45 not found in the structures of three solute importers BtuCD, HI1470/1, and ModBC from the same prote

46 rmally known as HI1470/71) is also a Type II importer, but its substrate, molybdate, is approximately

47 Bacillus subtilis expresses numerous iron importers, but iron efflux has not been reported.

48 Less is known about Type II importers, but much of what we do know has been observed

49 EmrE, a drug/H(+) antiporter to a polyamine importer by a single mutation.

50 ed on structural and functional studies, ABC importers can be divided into two distinct classes, type

51 nvolved in vacuolar iron storage is the iron importer Ccc1, which facilitates iron entry into the vac

52 rs affects the activity of the vacuolar iron importer Ccc1.

53 he previously described Msc2p-Zrg17p ER zinc importer complex functions mainly in zinc-depleted condi

54 r copper is regulated not only by the copper importer CTR1 (copper transporter 1) but also by the cop

55 ses alveolar macrophage expression of the Cu importer (Ctr1) and ATP7A, a transporter implicated in p

56 rease expression of the high affinity copper importer, CTR1, and stimulate copper uptake.

57 everal iron transporters, including the iron importer DMT1 (Ireg1, MTP, DCT1) and the iron exporter f

58 The substrate selectivity of this importer ensures the high-affinity uptake of essential m

59 unctions as the principal mitochondrial iron importer essential for haem biosynthesis in vertebrate e

60 -K(+)-Cl(-) cotransporter 1 (NKCC1), a Cl(-) importer expressed in most cell types mainly during post

61 xpression, and towards regions of high auxin importer expression.

62 of all bacteria, ATP binding cassette (ABC) importers facilitate the uptake of several vital nutrien

63 Currently, the 27 registered importer facilities import approximately 8500 nonhuman p

64 Importer facilities receive regular inspections, and com

65 during transit and quarantine and initiated importer facility compliance inspections.

66 ed with increased expression of the Zn(2)(+) importer family members Slc39a6, Slc39a7, and Slc39a8, a

67 Type I importers follow a strict alternating access mechanism t

68 suggested that Yfe, a well-characterized C9 importer for manganese (Mn) and iron in Y. pestis, might

69 ner membrane, functions as an essential iron importer for the synthesis of mitochondrial heme and iro

70 Escherichia coli maltose transporter, an ABC importer for which an intact structure is available both

71 an electroneutral Na(+)-dependent HCO(3)(-) importer for which the precise mode of action remains un

72 edicted to homodimerize and form peroxisomal importers for fatty acyl-CoAs.

73 28) function as essential mitochondrial iron importers for heme and Fe/S cluster biogenesis.

74 exclusion from these bodies, and can act as importers for otherwise-excluded nucleic acids, which su

75 We identified key exporters and importers from the number of shipments a country sent an

76 tide importer (oppABCDF) and glycine betaine importer (gbuABC) allowed DeltadacA mutants to grow in r

77 tion, which has two inorganic phosphate (Pi) importers, genomic analysis suggested that S. aureus pos

78 Mutants that lack MntH, the importer, grow at wild-type rates, indicating that manga

79 nial vault, expressed high levels of lactate importers, harbored abundant mitochondria, metabolized l

80 er acidic conditions, although a low-pH Fe2+ importer has not been previously identified.

81 The human high affinity copper importer, hCtr1, and its yeast and murine orthologues ha

82 raction between the Yersinia pestis ABC heme importer (HmuUV) and its partner substrate-binding prote

83 ing domains (SBD) of an ATP-Binding Cassette importer in real-time.

84 activity of putative vacuolar glucosinolate importers in these peripheral cell layers.

85 colocalization with the principal root iron importer IRON-REGULATED TRANSPORTER1 (IRT1).

86 CCC1, a vacuolar iron importer, is a Yap5-regulated gene, and deletion of eith

87 d, and transferrin receptor (TFR1), the iron importer, is increased in tumor tissue from patients wit

88 t distinctly different from the three solute importers it seems likely that the TMDs of ABC importers

89 Mutating the nuclear importer karyopherin alpha3 also leads to reduced toxici

90 oncurrently, ectopic expression of the auxin importer LIKE AUX1 and boundary gene NO APICAL MERISTEM

91 l structures of the Escherichia coli maltose importer (MalFGK2) in complex with its substrate binding

92 ting that ATP-binding cassette exporters and importers may use similar mechanisms to achieve alternat

93 imilarity to the Ctr1 plasma membrane copper importer, microscopic and biochemical fractionation stud

94 ble interest in using bumetanide, a chloride importer Na-K-Cl cotransporter antagonist, for treatment

95 o auxin exporters, leaves also express auxin importers, notably members of the AUX1/LAX family.

96 movement of other molecules, such as the Ran importer NTF2.

97 ceptor (IFNGR)-1/STAT1alpha with the nuclear importer nucleoprotein interactor 1.

98 s now as an electrochemical potential driven importer of a new set of substrates: aliphatic polyamine

99 nd has therefore been proposed to be a major importer of dietary fatty acids.

100 The MetNI methionine importer of Escherichia coli, an ATP binding cassette (A

101 The largest center was a net importer of kidneys, whereas small and medium-sized cent

102 adding the tgd1 mutation, which disables an importer of lipids into plastids to create adg1suc2tt4tg

103 Therefore, Kap114 is an importer of TBP into the nucleus, but alternative import

104 uABCD (also called OpuC) encodes a predicted importer of the compatible solute glycine betaine.

105 The results reveal that Spain is a net importer of water.

106 ATP binding by Type I ABC transporters (importers of amino acids, sugars, peptides, and small io

107 ve exporting industries have argued that the importers of emissions-intensive goods should bear the r

108 Here we compared two ABC importers of identical substrate specificity (molybdate/

109 hai, Beijing, and Tianjin, are already large importers of net virtual water at the expense of water r

110 riginally believed to be present only in the importers of the ABC family.

111 In Type II ABC transporters (importers of trace elements, e.g. vitamin B12, heme, and

112 ss of function mutations in the oligopeptide importer (oppABCDF) and glycine betaine importer (gbuABC

113 omain of the ATPase subunit of the carnitine importer OpuC.

114 A GFP fusion to the choline importer protein LicB showed clear membrane localization

115 Protein abundance of the heme importer, proton-coupled folate transporter, was related

116 cation of TMEM14C as a protoporphyrinogen IX importer provides a genetic tool for further exploring e

117 the conformational plasticity of the maltose importer, providing insights into the ATPase stimulation

118 In addition to these exporters, one importer, Pseudomonas aeruginosa Q9I147, was also identi

119 ) and a reduced KCC2/NKCC1 (Na(+)/K(+)/Cl(-) importer) ratio.

120 cortical LDL receptor (LDL-R; a cholesterol importer) regulation was gauged by quantifying its mRNA.

121 TNPO3 is a nuclear importer required for HIV-1 infection.

122 used by mutations in hZIP4 (SLC39A4), a zinc importer required for zinc uptake in enterocytes and oth

123 This importer requires a periplasmic maltose-binding protein

124 NKCC1, which serve as chloride exporters and importers, respectively.

125 mbers of a highly conserved family of copper importers responsible for copper uptake across the plasm

126 ion of CCC1, which encodes the vacuolar iron importer, results in high iron sensitivity due to increa

127 These three structural motifs in small ABC importers show a high degree of correlation in motion an

128 in the germline requires the dsRNA-selective importer SID-1.

129 emic/exogenous (exo)-RNAi pathway: the dsRNA importer, SID-1 and the argonaute, RDE-1.

130 eted endocytic degradation of the amino acid importer Slimfast.

131 elements only in the subfamily of small ABC importers, suggesting a distinct mode of NBD-TMD couplin

132 bridges similar to the ATP-binding cassette importers, suggesting that ATP-binding cassette exporter

133 The Ctr1 protein is a high-affinity Cu(+) importer that is structurally and functionally conserved

134 ll, the COS cell, with cDNAs for a bile acid importer, the ileal bile acid transporter (IBAT), as wel

135 n, including the principal hepatic bile acid importer, the Na(+)/taurocholate co-transporting polypep

136 n part to the constitutive expression of two importers: the proton-dependent NRAMP family transporter

137 tion enables the production of the ferric-BB importer to be activated by the presence of its cognate

138 tly associated with the placental nonheme Fe importer transferrin receptor 1 (TfR1).

139 this new study, PlaP, a putative putrescine importer, was characterized in P. mirabilis.

140 rstand mechanistic differences among Type II importers, we focused our studies on MolBC, for which al

141 imilar to that of ATP binding cassette (ABC) importers, whereby both systems share two homologous ATP

142 new paradigm whereby Atp8b1 is a cardiolipin importer whose capacity to remove cardiolipin from lung

143 homeostasis is complex, involving both zinc importers (Zip3) and zinc exporters (ZnT-1, ZnT-2, and Z