ライフサイエンスコーパス: impose

1 ed among each factor and across the stresses imposed.

2 ine expected if new or increased threats are imposed.

3 ess a substantial orthorhombic distortion is imposed.

4 fferent root tissues according to the stress imposed.

5 Handgun waiting periods are laws that impose a delay between the initiation of a purchase and

6 demic disease, in its totality, continues to impose a far higher public health burden than epidemic d

7 orkforces-occupational exposures continue to impose a heavy burden of disease.

8 walking on a split-belt treadmill, which can impose a left-right asymmetry in step lengths.

9 However, quinoline-based ALLINIs impose a low genetic barrier for the evolution of resist

10 Because chronic liver diseases impose a major health burden worldwide affecting the hea

11 Here we propose a simple method to impose a mechanical compression on individual cells with

12 th SAR=2-7, though kinetic factors seemingly impose a more restricted upper limit for HOU-3 (SAR appr

13 al bowel disorders (FBD) is critical as they impose a negative economic impact to the global health c

14 alization preference of the GrabFP traps can impose a novel localization on GFP-tagged target protein

15 reduced model uncertainty and allowing us to impose a priori available physical information.

16 These guidelines are not intended to impose a standard of care.

17 rojected to enhance CLL survivorship but can impose a substantial financial burden on both patients a

18 and the current threats on their populations impose a sustainable exploitment based on sound scientif

19 ttle emphasis has been placed on the need to impose a time-averaged constant growth rate across all m

20 the highest in the brain and is predicted to impose a transient temporal filter on postsynaptic cells

21 e show that APOBEC3A and APOBEC3B activities impose a unique type of replication stress by inducing a

22 The recent outbreak of Zika virus (ZIKV) has imposed a serious threat to public health.

23 The disturbance imposed a strong selective pressure that persisted for u

24 ng of the RAF, MEK and ERK kinases, however, imposed a sufficiently high fitness threshold to prevent

25 nt resulting from a federal law in 1994 that imposed a temporary waiting period on a subset of states

26 G loop establishes task-set selection, which imposes a (unidirectional) constraint on a subordinate S

27 These results show that H3K4 methylation imposes a barrier to efficient nuclear reprogramming and

28 In this study, we test whether fire imposes a broad selective force on a key fire-tolerance

29 that the posttranscriptional regulator RsmA imposes a concerted repression on all three T6SS cluster

30 t velocity Off-Vertical Axis Rotation (OVAR) imposes a continuously varying orientation of the head a

31 Producing antimicrobials imposes a fitness cost on burying beetles, which rises w

32 nucleoporins assemble into the NPC scaffold imposes a formidable challenge.

33 n laser-driven particle acceleration schemes imposes a limit on the total acceleration achievable in

34 This requirement imposes a limitation on the imaging speed as digital mic

35 symmetry associated with cyclic competitions imposes a limitation on the resulting coexistence states

36 and to protein substrates in various forms, imposes a major challenge for these studies.

37 d that an open-state stabilization of the PD imposes a mechanical load on the VSD, which causes its m

38 ta indicate that the KL oncological genotype imposes a metabolic vulnerability related to a dependenc

39 MW imposes a negative impact on attention-based task perfor

40 es the first case in which a MAPK, Erk/Mpk1, imposes a phenotype via a mechanism that is independent

41 appropriately regularized, which effectively imposes a prior on the activity profiles.

42 improve the quality of activity inference by imposing a constraint on the minimum spike size.

43 y storage, obesity, and associated diseases, imposing a costly burden on current health care.

44 Imposing a further constraint on the maximum entropy dis

45 nonlinearity of nematic liquid crystals and imposing a linear variation of the background alignment

46 the method of least squares, are modified by imposing a penalty for each explanatory variable used.

47 edge is represented as a continuous envelope imposing a periodic moving velocity boundary condition o

48 and activated target gene expression states, imposing a static environment on the synthetic regulator

49 report a novel fabrication process flow for imposing a strong lateral potential modulation onto a ca

50 We discovered that imposing a time-restricted feeding (TRF) regimen in whic

51 ion that may be more regional than uniformly imposed across the cline.

52 on, these treatment strategies are likely to impose additional selection pressure to drive acquisitio

53 on oxygen uptake and walking economy without imposing altered gait patterns.

54 They also impose an observable limit-known as the quantum backacti

55 Climate change imposes an urgent need to recognise and conserve the spe

56 Imposing an additional adjacency constraint within calcu

57 imultaneous changes in gene expression after imposing an environmental stress that accentuates the re

58 els, indicating that variability is actively imposed and not a passive statistical effect of the redu

59 : In human addicts, abstinence is often self-imposed and relapse can be triggered by exposure to drug

60 regulating axon trafficking parameters, and imposing architectural rearrangements such as the nodes

61 30-80 nm per hs) and, when V0 shortening is imposed at the end of LR, n can be as low as 1-4.

62 limit the degree to which chemical diversity imposed at the ligand-GPCR interface is propagated to th

63 We estimate that the ELGs will impose average net costs of $3.01 per cubic meter for ch

64 In many human alcoholics, abstinence is self-imposed because of the negative consequences of excessiv

65 he amount of co-delivered carrier materials, imposing biological burdens to patients.

66 A common method for imposing both dry and wet years is to alter each ambient

67 latory burden-particularly unnecessary, self-imposed burden-in the ACUP is particularly important to

68 e neutrophil genome into a confined geometry imposed by a multilobed nuclear architecture.

69 ons define a precise metabolic vulnerability imposed by a recurrently mutated oncogene.

70 The geometric constraints imposed by a tetradentate P4N2 ligand play an essential

71 Unlike the caging imposed by an inert matrix, an active lattice participat

72 reduce the hemodynamic and metabolic burden imposed by AS.

73 translation at times of Ssb binding, mainly imposed by biases in mRNA secondary structure, codon usa

74 We compared the costs imposed by care on the survival and residual reproductiv

75 Dominant tolerance imposed by CD4(+)Foxp3(+) T regulatory cells can activel

76 Constraints imposed by comorbidities (notably cardiovascular disease

77 an additional tool for considering the risks imposed by conduction abnormalities in heart failure pat

78 Limits on evolution imposed by constraints on sequence and structure were ex

79 Focused flow in the upper mantle imposed by deformation of the lower crust localizes upli

80 necessary condition for pseudogap formation, imposed by details of the Fermi surface, is a strong con

81 of these weak sidelobes approaches the limit imposed by diffraction from the finite field extent in t

82 t quantifies the strength of gene regulation imposed by each class of regulatory elements, and found

83 quantitative measure of the technical burden imposed by each step of bioinformatics analyses, reveali

84 nhibitory effects of cellular depolarization imposed by elevating extracellular [K(+)], and KCNQ2 was

85 e data illustrate that the cognitive demands imposed by error processing can interfere with, rather t

86 relative importance of intrinsic constraints imposed by evolved physiological trade-offs versus the p

87 ally when depletion was limited (a condition imposed by fatiguing stimulation, long-lasting depolariz

88 This proliferative barrier imposed by fatty acid metabolism in hCOs could be rescue

89 rn covariations, the role of the constraints imposed by finite resource supply, and a comprehensive e

90 prevent runaway dynamics of synaptic weights imposed by Hebbian-type learning.

91 , are needed to counteract positive feedback imposed by Hebbian-type rules on synaptic weight changes

92 be directly induced by the increased strain imposed by high IOP.

93 s the ability to withstand numerous stresses imposed by host immunity.

94 s of these two key principal amine compounds imposed by hydrogen bonding to water, where a pH-depende

95 that ageing microglial phenotype is largely imposed by interferon type I (IFN-I) chronically present

96 fore, the regulation of Dam1 phosphorylation imposed by Ipl1 kinase is critical for faithful chromoso

97 uld be due to a lower structural flexibility imposed by its complex structure.

98 owth factor by releasing it from the latency imposed by its surrounding prodomain.

99 urrents in a device setup due to limitations imposed by low light absorbance by protein monolayers an

100 This is in the context of constraints imposed by networks of cell walls that both adhere cells

101 DPYD expression, following metabolic stress imposed by nucleotide imbalance.

102 The evolutionary pressure imposed by phage predation on bacteria and archaea has r

103 maintained by limits to bacterial dispersal imposed by physical distance between hosts.

104 xic butterfly Heliconius numata Positive FDS imposed by predators on mimetic signals favors the fixat

105 i recovery from intracellular alkaline loads imposed by reducing [CO2 ].

106 d highlights that the evolutionary pressures imposed by sex chromosome dosage reductions in different

107 On average, losses on predictive properties imposed by subsampling were negligible, usually below 1%

108 In practice, the physicochemical constraints imposed by surfactant molecules limit the access to this

109 ing phenology respond jointly to constraints imposed by temperature and resource phenology.

110 pecific chromosomal replication fork barrier imposed by the binding of Tus proteins to an array of Te

111 tegy minimizes the hindrance of NP diffusion imposed by the brain extracellular matrix and reduces NP

112 rafficking paradigms adapted to the barriers imposed by the closed circulatory system.

113 ty and sensitivity (0.1% (w/w)) requirements imposed by the European Commission for animal proteins d

114 physical and biological constraints that are imposed by the fluid environment and the evolutionary co

115 At its simplest, dormancy can be imposed by the formation of a simple physical barrier ar

116 bserved genotypes conditional on constraints imposed by the genotypes of other pedigree members.

117 sis involves lowering of the kinetic barrier imposed by the hydrophobic thickness of the membrane.

118 Instead, such concentrations are imposed by the ion-exchange equilibrium condition, witho

119 arriers face significant challenges that are imposed by the pathophysiological barriers that lie betw

120 We propose that this is an entatic state imposed by the protein on the active site through relati

121 Despite the limited counting rate imposed by the readout electronics, we show that both co

122 ltaKD) freed from autoinhibitory constraints imposed by the regulatory domain is catalytically compet

123 e ATPase-dependent 120 degrees power strokes imposed by the relative positions of the central and per

124 conformations formed result from constraints imposed by the relatively rigid and sterically bulky rep

125 hesis and is mediated by spatial constraints imposed by the ribosomal exit tunnel as well as self-int

126 nism does not depend on physical constraints imposed by the shape or size of specific organs.

127 ly smaller (97 degrees ) due to restrictions imposed by the shorter linker.

128 s are usually disregarded due to the damping imposed by the surrounding fluid.

129 tilization suffers from intrinsic challenges imposed by the triplet ground state of O2 and the dispar

130 an pathologies, limitations to drug delivery imposed by the unique characteristics of different disea

131 A maximum speed constraint imposed by the use of RSPs would indicate a performance

132 le despite the potential spatial constraints imposed by their extensive thylakoid network.

133 s likely to be determined by the constraints imposed by their position within the CSC rather than the

134 ons of the electronic and structural effects imposed by these surface additives and their removal mec

135 ion protein (FP) that evades the limitations imposed by this system.

136 absence of mitotic rounding, geometric cues imposed by tight cell packing prevail and cells divide a

137 y and late transcripts, similar to the block imposed by TRIM5alpha.

138 Microbes drive ecosystems under constraints imposed by viruses.

139 gnificantly elongated, whereas Mn-limitation imposed by zinc addition leads to cell shortening.

140 hatases contribute to cell-cycle ordering by imposing Cdk thresholds.

141 ficulty of high computational complexity and imposes challenges to the accuracy of identification sta

142 Recent progress in understanding the niche-imposed chemoresistance mechanisms will likely contribut

143 Neutrophils respond to imposed chemotactic gradients, and migrate in response t

144 y, it has been recognized that mutations may impose combinatorial defects in CFTR channel biology.

145 e-dimensional architecture of plant canopies imposes complex light dynamics, but the drivers for phot

146 rystal plasticity varies systematically with imposed conditions, this raises the possibility that it

147 pt a different strategy inspired by pressure-imposed configurations in granular flows that specifical

148 Infectious diseases impose considerable burden on society, despite significa

149 iors involve cell-shape transformations that impose considerable changes in the cell's surface area,

150 st introduce Dual Label Propagation (DLP) to impose consistent associations with the entire phenotype

151 in which approximately 30% additional to the imposed constraints is found to be specific.

152 to changes in diets with minimal additional imposed constraints on the model.

153 We propose that successful speech processing imposes constraints on the self-organization of synchron

154 c pathways may contribute to overcoming host-imposed copper toxicity.

155 We used a 3.5-A cryo-EM reconstruction with imposed D7 symmetry to further analyze structural hetero

156 r, including DNA methyltransferases where it imposes de novo DNA methylation.

157 , a highly malignant childhood brain tumour, impose debilitating effects on the developing child, and

158 dy of fasters during Ramadan shows that self-imposed deprivation, which carries no implications regar

159 pulations face different environments, which impose different selective pressures.

160 or are isolated from, the bulk population by imposing different rates of birth, death and movement.

161 c substituent and the polarized [Ru-Cl] unit imposes directionality onto the ligand sphere of the rel

162 ll changes in force responding to externally imposed displacements, a behavior characterized by low l

163 ults reveal a novel effect of CD44, which is imposed downstream of ECM-mechanosensing and determines

164 Monocular deprivation (MD) imposed early in postnatal life elicits profound structu

165 The existing SCCA methods impose either the l 1 -norm or its variants to induce sp

166 alf-myosin filament (n) during V0 shortening imposed either at the end of LR or at the plateau of the

167 amic model to predict the nerve responses to imposed electric fields.

168 endent on the amplitude and frequency of the imposed electronic signals.

169 To this end, we impose end-of-century climate on today's European econom

170 In addition, we show that imposing energy conservation in SSR cascades allows us t

171 The HIV pandemic continues to impose enormous morbidity, mortality, and economic burde

172 holds; relatively lower reproducibility when imposing extraneous constraints on residual heterogeneit

173 creases, although there were limited studies imposing extreme precipitation change, and there was con

174 We endorse this approach for imposing extreme precipitation years because it simultan

175 Thus most SCCA methods impose [Formula: see text]-norm onto the individual feat

176 nctional architecture of cerebral cortex may impose fundamental restrictions on the spread of artific

177 cation procedure and an analytical step that imposes general biological constraints.

178 In particular, we imposed geometric frustration upon a prototypical system

179 ng (fundamental-change view) or because they impose greater processing demands (processing-demands vi

180 The harsh northern conditions may impose greater selective pressure on timing of growth ce

181 ared with open surgery, laparoscopic surgery imposes greater ergonomic constraints on surgeons.

182 ng awareness of environmental sustainability impose growing new demands on the nature degradability o

183 tory burden, particularly if institutionally imposed, has become a concern for institutions as increa

184 that experimental studies sometimes actually impose higher levels of stress than organisms experience

185 ion of different EV populations are missing, imposing important limitations to understanding EV funct

186 s migration depends on N-cadherin that, when imposed in ectodermal cells, is sufficient to trigger th

187 Two acidification profiles were imposed, in order to mimic the pH normally obtained in s

188 Plasmid-mediated synthesis of eIF4G imposes increased global gene expression stochasticity a

189 powerfully regulating granule cell firing by imposing inhibition during a specific time window.

190 However, if we implement actual control by imposing input signals on the minimum set of driver node

191 Whether different microenvironmental cues impose invasive or therapy-resistant phenotypes via a co

192 gh which diet-induced obesity during puberty imposes its long-lasting effects on sleep-wake behavior.

193 Climate variability can impose large fitness costs on insects showing diapause a

194 umber of cells that can be assessed and thus impose limitations on the ability to measure heterogenei

195 tunnelling current through grain boundaries imposes limits on the maximum magnetoresistance that can

196 ssed on a simple flat treadmill (FTM), which imposes little demands on supraspinal structures as is t

197 Fetal perturbations by OSA during pregnancy impose long-term detrimental effects manifesting as meta

198 data or the partial coherence of the source impose lower resolution limits.

199 lgae, macroalgae are larger in size, thereby imposing lower separation and drying costs.

200 onic peptides has resulted in the ability to impose major morphological changes on the endosymbionts.

201 This pericarp-imposed mechanical dormancy is released by the activity

202 ponse to internally generated and externally imposed mechanical stresses, endowing the cell with the

203 se material encounters a target, it expands, imposing mechanical stress on the wire and altering its

204 nt Abeta aggregation itself is sufficient to impose memory circuits dysfunction, which propagates to

205 del predicted nicely the consequences of the imposed modifications.

206 ion of male-biased genes, and experimentally imposing monogamy on Drosophila melanogaster has led to

207 in this area, regulators and legislators may impose more draconian measures.

208 if the same decrease in light intensity was imposed more than 10 h after dawn.

209 , revealing common switching mechanisms that impose multistate behavior.

210 they also change their environment, thereby imposing new selective pressures that can modify their b

211 (ETPs) could escape T cell fate constraints imposed normally by a Notch-inductive microenvironment a

212 Spaceflight imposes numerous adaptive challenges for terrestrial lif

213 lecular mechanisms and the constraints these impose on a biological system are accounted for.

214 n result from the drastic alterations humans impose on ecosystems.

215 e, adaptation to the strong selection humans impose on natural systems?

216 ature to cover the choices that environments impose on the metabolism and function of immune cells an

217 her metasurfaces to control the changes they impose on the polarization, intensity, phase, spectrum a

218 major roadblocks that normal aging processes impose on tissue regeneration.

219 This mainly occurs when fecundity costs are imposed on mate search, and provides an explanation for

220 The steric restrictions imposed on molecular strands by knotting can impart sign

221 g systems to overcome the fundamental limits imposed on selection processes in networks operating und

222 However, the volume constraint imposed on the FICI requires less power consumption comp

223 ng contactless a stress field which is to be imposed on the matrix material.

224 nts were related to the conformational poise imposed on the pump.

225 understanding of how spatial restriction is imposed on the spread of inflammatory lesions and highli

226 is also evidence that MHC restriction can be imposed on the TCR repertoire during thymic development,

227 detected because the structural distortions imposed on the tetraoxacyclohexane subunit in [3.2.2]tet

228 ively, these data quantify where limitations imposed on the Treg TCRbeta repertoire results in a popu

229 eds of sighted creatures and the constraints imposed on them by metabolism, anatomy, and the structur

230 Rather, it suppresses inhibition imposed on these wide-field cells by another subpopulati

231 sure of the space-time filter that the brain imposes on a visual scene has been elusive.

232 ent during V0 shortening (n) is estimated by imposing, on tetanized single fibres from Rana esculenta

233 lar metabolites act as tumor morphogens that impose order within the microenvironment, much like sign

234 instructed either to not intervene with the imposed perturbations or to explicitly intervene so as t

235 groups and/or auxiliaries have emerged, but impose practical restrictions, especially in complex mol

236 How M. tuberculosis alternates between host-imposed quiescence and sporadic bouts of replication to

237 We imposed repeated hypertensive challenges using either N(

238 ace of each solute particle is engineered to impose repulsive forces strong enough to overpower van d

239 Physically blocking pili imposed resistance to pilus retraction, which was suffic

240 e (via glucocorticoid actions) and infection impose resource trade-offs that shape optimal allocation

241 Our results also impose restrictions on the potential role of atmospheric

242 licable direct physiological effect: climate-imposed restrictions on activity.

243 s the requirement of a gate electrode, which imposes restrictions on sensor device architectures and

244 croresonators requires anomalous dispersion, imposing restrictions on materials and resonator design.

245 The current study tests the hypothesis that imposing rhythms in the mouse anterior cingulate cortex

246 rly detection of an emerging pathogen within imposed sample size and/or cost constraints, and demonst

247 nd the stability of photoelectrode materials impose serious restrictions on its advancement.

248 pes of errors, biases and uncertainties that impose several statistical and computational challenges

249 om images and G was computed as the ratio of imposed shear stress to measured shear strain.

250 acterized by rapid cleavage divisions, which impose significant constraints on metabolic pathways.

251 ttent hypoxia (IH), a hallmark of OSA, could impose significant long-term effects on somatic growth,

252 termittent hypoxia, a hallmark of OSA, could impose significant long-term effects on somatic growth,

253 matory bowel diseases (IBDs) are chronic and impose significant, multidimensional burdens on patients

254 the largest energy end-use of buildings that imposes significant burden on the society.

255 ble to coherent noise (speckle noise), which imposes significant limitations on its diagnostic capabi

256 Such a long list imposes significant requirements on nano-sized carriers.

257 ng steady-state microbiota composition as it imposes significant restrictions on the allowable commun

258 etworks into physically controllable ones by imposing slightly augmented set of input signals on prop

259 By imposing sparsity constraints we have enhanced the inter

260 The DA transporter (DAT) imposes spatial and temporal limits on DA action, and pr

261 positioning in the architectural context of imposed specific interactions from nC-SAC is highly impo

262 We impose spin-selectivity by coating the anode with chiral

263 The origins of giraffe's imposing stature and associated cardiovascular adaptatio

264 s is the ability of heterogeneous network to impose steering during motility.

265 cture can tune the rate of network growth to impose steering during motility.

266 strated to increase rates of cyclization and impose stereochemical constraints on the reactions.

267 ng and biomechanical evidence that adduction imposes strain on the ONH and peripapillary tissues.

268 Host resistance imposes stress on invading pathogens that can lead to ch

269 d activate signaling pathways in response to imposed stresses [5-9].

270 osphorylated in response to a number of host-imposed stresses, and is essential for virulence.

271 ns, is dependent on robust responses to host-imposed stresses.

272 During externally-imposed stretches of passive, i.e. electrically-quiescen

273 , the short penetration depth of soft X-rays imposes stringent constraints on sample type, preparatio

274 n between energy consumption and dissipation imposes stringent physical constraints on the informatio

275 Anatomical connectivity imposes strong constraints on brain function, but there

276 nerate air, water, and solids emissions that impose substantial human health, environmental, and clim

277 mportant role in pulmonary tumorigenesis and imposes substantial clinical impact on development of no

278 egrating such a rigorous set of requirements imposes substantial complexity and difficulty in the des

279 Treatments that impose the highest fitness threshold will likely prevent

280 o activates AXL and suppresses senescence to impose the MITF-low/AXL-high drug-resistant phenotype ob

281 that the imino acid proline and not tRNAPro imposes the primary eIF5A requirement for polyproline sy

282 that exactly mimics these experiments, while imposing the 1:1 constraint.

283 e of the underlying regulatory processes and imposing the condition of flux balance, we derive a quan

284 However, imposing this prepattern's condition of high FGF and low

285 r suffer from effects of arbitrary, a priori-imposed timescales, which should instead be extracted fr

286 o be dependent on the stress and constraints imposed to component contraction during cooling, which m

287 Indeed, the macromolecular damage imposed to malignant cells by RT initiates one or multip

288 a, we measured flow profiles and drag forces imposed to trapped red blood cells of living zebrafish e

289 f selfish genes to shape genomes, even while imposing tremendous costs to fertility.

290 Detection of biomarkers in saliva imposes two major challenges associated with the low ana

291 The underground environment imposes unique demands on life that have led subterranea

292 h and economic development are forecasted to impose unprecedented levels of extinction risk on many m

293 is influenced by the ambulatory constraints imposed upon the animal by the boundaries of the explore

294 behavior emerges when appropriate conditions imposed upon the couplings are satisfied, justifying the

295 hese glycans is shaped by steric constraints imposed upon them by the native folding of the viral spi

296 dividuals with slow circadian clocks or when imposed wake-times occur after sunrise.

297 embolizing bubbles in the stem xylem during imposed water stress.

298 considerations; clinical study requirements imposed when PrEP was not approved through the regulator

299 Small-scale neuronal networks may impose widespread effects on large network dynamics.

300 ures, suggesting degradation of cool refugia imposed widespread metabolic or other costs.