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1  linearity of the Watson-Crick B-form duplex imposes limitations on 3D crystal design.
2     To solve the class discovery problem, we impose a metric on a set of tumors as a function of thei
3     We conclude that CD4 and CD8 coreceptors impose MHC specificity on a broader alphabetaTCR reperto
4  focal ischemia, and the additional workload imposed by SD on a tissue already compromised by a marke
5 le in stress-induced behavioral deficits, we imposed social isolation on a genetically vulnerable mou
6 idered the expression changes induced by the imposed stress on a group of fungal genes playing a key
7 ers in organic light-emitting diodes (OLEDs) imposes demanding requirements on a host material.
8                                 Supercoiling imposes stress on a DNA molecule that can drive suscepti
9 licable direct physiological effect: climate-imposed restrictions on activity.
10 ve impairments and pediatric chronic illness impose significant limitations on adolescents' self-care
11 se an evolved cognitive revenge system which imposes retaliatory costs on aggressors.
12 unds derived from the models and experiments impose limitations on all nanophotonic systems.
13                          Chromatin structure imposes significant obstacles on all aspects of transcri
14           One solution to this problem is to impose retaliatory costs on an aggressor so that the agg
15  signaling directs motor pool patterning and imposes topographic order on an underlying identity-base
16                 We assessed the effect of an imposed sedentary routine on appetite, energy intake (EI
17 C-II interactions and DM catalytic activity, imposing challenges on approaches to determine pH effect
18                           This energy policy imposes pressure on available freshwater resources and i
19 l-time processing of neuronal signals, which imposes excessive requirements on bandwidth, energy and
20 versification of lineages, but they may also impose functional constraints on behaviors such as locom
21  sets of glutamatergic inputs to the BLA can impose opposing actions on BLA-mediated behaviors; speci
22 d aspects of trait genetic architecture, can impose constraints on both local adaptation and speciati
23             Protein-protein interactions may impose constraints on both structural and regulatory evo
24 at these antiparasitic cardenolides can also impose significant costs on both uninfected and infected
25                Protein-RNA complex formation imposes specific conformations on both components that c
26                      Anatomical connectivity imposes strong constraints on brain function, but there
27 hosus) compare male frog calls, and how this imposes selection on call evolution.
28            Using neutralizing antibodies, we imposed a blockade on CD11b(+) cells' recruitment to tum
29 es containing this tRNA gene adjacent to HML imposes dependence on cell cycle progression for the ful
30 nsertion into membrane bilayers, which could impose detrimental effects on cells.
31  both diamide and H(2)O(2) have been used to impose oxidative stress on cells, these different oxidan
32 s a complex with Mad2, which is required for imposing mitotic arrest on cells in which the spindle as
33                     Although physical effort imposes a cost on choice, when and how effort cost influ
34  and molecular biology of the bacterial cell imposes constraints on chromosome composition, maintaini
35 fferences in vapor-pressure deficits did not impose additional constrictions on ci/ca in the past.
36  set of experiments, Pma1-G381A was found to impose its phenotype on co-expressed wild-type ATPase, t
37 en reported rely on external electrodes that impose limitations on complexity.
38             We found strong linear selection imposed by pollinators on corolla tube length at all sit
39 ites from the Tn3 recombination site res can impose topological selectivity on Cre/loxP recombination
40                                              Imposing curvature on crystalline sheets, such as 2D pac
41                 Although physical effort can impose significant costs on decision-making, when and ho
42  is often enforced through institutions that impose sanctions on defectors.
43 ted games within groups, punishment works by imposing costs on defectors so that it pays them to swit
44 e-specific expression, suggesting that TRA-1 imposes sex specificity on developmental timing.
45 improvement in device quality, this geometry imposes severe limitations on device architecture and fu
46 d residues eliminates the ability of P22R to impose structural changes on DNA and to recognize non-co
47 nctly timed electrical drives collaborate to impose rhythmicity on Drosophila clock neurons.
48 ion of male-biased genes, and experimentally imposing monogamy on Drosophila melanogaster has led to
49                                           By imposing sevenfold symmetry on each of the subunits of t
50  dynamics of many species and is expected to impose natural selection on ecologically important trait
51                     Time-reversal symmetries impose stringent constraints on emission and absorption.
52                            In addition, PCNA imposes strand specificity on enzyme function, and by lo
53       The cell cycle transcriptional program imposes order on events of the cell-cycle and is a targe
54                    As these deletion mutants impose less inhibition on exocytosis, we suggest that to
55 y are prohibitive for large sample sizes and impose limitations on experimental design.
56   However, the short optical wavelength also imposes stringent requirements on fabrication.
57 e development of immunological tolerance and impose a burden on families and day care.
58 dependent selection, because leaders gain by imposing their preferences on followers, but fail to coo
59  displacement and 100 mug force precision to impose small deformations on fresh bovine sclera, iris,
60   In addition, overexpressed Syt-1 and Syt-7 impose distinct effects on fusion pore expansion and gra
61 scale-free properties of the fMRI signal and impose constraints on future models of neurovascular cou
62 ite global rock phosphate (Pi) reserves will impose major limitations on future agricultural producti
63                            The immune system imposes limitations on gene transfer into the brain.
64        The packaging of DNA into nucleosomes imposes obstacles on gene transcription, and histone-mod
65 y proteins search for their sites on DNA can impose constraints on genome structure.
66 rsed element 1 (LINE-1) retrotransposons may impose significant changes on genomic structure and func
67  ;good cop: bad cop' team of CSN-5 and KGB-1 imposes a balance on GLH-1 levels, resulting in germline
68  syndromes, respectively, disrupt a Mediator-imposed constraint on GLI3-dependent Sonic Hedgehog (SHH
69          We focus on the ability to flexibly impose constraints on haplotype effects, which allows fo
70 h pressures in liquid chromatography (UHPLC) imposes stringent requirements on hardware such as pumps
71 musculoskeletal disorders, and diabetes will impose new challenges on health systems.
72 ncreasing in incidence throughout the world, imposing enormous burdens on health care.
73                     This conflict appears to impose moral distress on healthcare providers and limits
74 tool for the study of the selective pressure imposed by microorganisms on host genomes.
75 dditional interactions have the potential to impose selection on hosts and parasites and influence th
76  combines with the high mortality of dogs to impose risks on households that depend on dogs as a sour
77                      The epidemic of obesity imposes unprecedented challenges on human adipose tissue
78  fabricated onto the underlying substrate to impose geometric constraints on immunological synapse fo
79  Membrane surface electrostatic interactions impose structural constraints on imported proteins.
80 ue loop near the active site that appears to impose size constraints on incoming substrates.
81 the blockade of NF-kappaB and MAPK signaling imposed by Yersinia on infected cells.
82              In combination, these molecules impose key decisions on innate and adaptive immune cells
83                          Spacecraft missions impose serious limitations on instrument volume, mass, a
84 sslinking experiments have demonstrated that imposing such restrictions on interhelical movement can
85                            The findings also impose new limitations on interpreting results from expe
86                                  However, it imposes a stress on intestinal commensals, as they also
87                              Host resistance imposes stress on invading pathogens that can lead to ch
88  Our results firmly establish that SAS-6 can impose cartwheel symmetry on its own and indicate how th
89 nd the stability of photoelectrode materials impose serious restrictions on its advancement.
90 he dense packing of this region is likely to impose severe constraints on its ability to change durin
91  xanthus aggregation uncovered in this study impose severe constraints on its underlying mechanisms.
92 sequently, the brain's limited energy supply imposes constraints on its information processing capabi
93 ble to coherent noise (speckle noise), which imposes significant limitations on its diagnostic capabi
94                                  Our results impose constraints on kinesin walking models and suggest
95 nges in microbiota should be considered when imposing husbandry variables on laboratory animals.
96 tal constraints such as seasonal desiccation imposed by living on land.
97            Small-scale neuronal networks may impose widespread effects on large network dynamics.
98                  The underground environment imposes unique demands on life that have led subterranea
99 at a cost to female fitness, or when females impose monogyny on males.
100 al methods for advanced polarization control impose demanding requirements on material properties and
101 croresonators requires anomalous dispersion, imposing restrictions on materials and resonator design.
102 acterized by rapid cleavage divisions, which impose significant constraints on metabolic pathways.
103 an be significantly affected by changing the imposed bounds on metabolite concentrations.
104 explain and compare the principal methods to impose artificial selection on microbiomes; discuss adva
105 rptiveness--volatility and water solubility--imposes physicochemical constraints on migration through
106 s to and returns from operational deployment impose stresses on military families and likely increase
107 xic butterfly Heliconius numata Positive FDS imposed by predators on mimetic signals favors the fixat
108  how tumour cells efficiently coordinate and impose specificity on miRNA expression and function in r
109 gest mineral oxidants in the environment and impose significant influence on mobility and bioavailabi
110 o perform biological functions is thought to impose strong limits on morphological evolution.
111 man sperm) contain accessory structures that impose mechanical constraints on movement, obscuring the
112     We speculate that N-terminal acetylation imposes conformational restraints on N-terminal residues
113                             Such a long list imposes significant requirements on nano-sized carriers.
114     However, to what extent functional sites impose evolutionary constraints on nearby or even more d
115 e is known of how sex determination pathways impose sex specificity on nervous system development.
116 ed by the regularity in the inputs to M1 can impose apparent structure on neural responses, in this c
117 tic basis by which Mediator facilitates REST-imposed epigenetic restrictions on neuronal gene express
118 e present MedEvi, a novel search engine that imposes positional restriction on occurrences matching m
119 red with the WT; the tryptophans in WT sybII impose sterical restraints on oligomer packing, thereby
120 t can be objectively labeled the "front." We impose this designation on one surface of an object acco
121 omoter complex and to overcome the sigma(54)-imposed block on open complex formation.
122 ely cofactor, Eyes absent, are sufficient to impose these fates on other mesodermal cells.
123 ble strategy to reduce sequence bias, though imposing selection constraints on other oligonucleotide
124                           Relaxation effects impose fundamental limitations on our ability to coheren
125 he sites of stimulus representation may also impose limits on our ability to attend to multiple items
126 ion, sources and modalities of group members impose serious limitations on our ability to rapidly ide
127 estration of p53 by the 55-kDa protein would impose additional inhibition on p53-mediated effects.
128 etween single genotype and coinfections will impose conflicting pressures on parasites, potentially s
129 on forests, indicating that this habitat may impose stresses on parasitoids that constrain them to at
130  moral integrity rather than as a "sword" to impose clinicians' judgments on patients.
131 reatment offers limited clinical benefit but imposes heavy burdens on patients, families, clinicians,
132 ed on chemically similar plants, they should impose selective pressures on plants to diverge chemical
133 c interactions with neighbouring species can impose selection on plasticity in functional traits, whi
134 m-dependent signal transduction pathways but imposes a handicap on popular CaM-based calcium biosenso
135 in both modes, and its distinctive structure imposes some constraints on proposed evolutionary mechan
136         Finally, we find that the constraint imposed by stickiness on protein divergence is proportio
137  manufacture of protein therapeutics; it can impose severe limitations on purification yields and com
138 pproaches: as studied in model organisms, it imposes physiologic constraints on receptor action and t
139 case, that metabolic state will feed back to impose itself on regulatory state.
140 cern that institutional review boards (IRBs) impose burdensome delays on research, little is known ab
141 ological Diversity has become a platform for imposing broad restrictions on research and development
142 holds; relatively lower reproducibility when imposing extraneous constraints on residual heterogeneit
143     Spermidine also counteracts the sequence-imposed bias on resolution.
144     Hydrogen peroxide (H(2)O(2)) was used to impose an insult on RGC-5 cells in culture.
145  the hypothesis that RNA interference (RNAi) imposes diversifying selection on RNA virus genomes, we
146                               This NF-kappaB-imposed restraint on ROS and JNK signaling is crucial fo
147 , the short penetration depth of soft X-rays imposes stringent constraints on sample type, preparatio
148 cal diversity in academia bear the danger of imposing political interests on science.
149 s the requirement of a gate electrode, which imposes restrictions on sensor device architectures and
150                          Limits on evolution imposed by constraints on sequence and structure were ex
151 y important, and overlap-evoked co-evolution imposes strong constraints on serine (S) residues in KSK
152 e in ovarian carcinoma and induction of SOX2 imposes CSC properties on SOC cells.
153 nce of age-associated cognitive impairments, imposing major burdens on societies.
154                          Infectious diseases impose considerable burden on society, despite significa
155   Monsoon rainfall and tropical storms (TSs) impose great impacts on society, yet their seasonal pred
156      Environmental impacts of energy use can impose large costs on society.
157 studies describing selective mechanisms that impose constraints on speciation are more rare than thos
158 Yet the niche may also induce pathologies by imposing aberrant function on stem cells or other target
159 ht on how microtubule couplers cooperate and impose important constraints on structural models for ou
160 le; (viii) protect confidentiality; (ix) not impose costs on subjects' estates or next of kin and not
161 ding spectral gaps, thermal fluctuations may impose restrictions on suggested quantum computing schem
162 ssed on a simple flat treadmill (FTM), which imposes little demands on supraspinal structures as is t
163           Here we found that ovarian cancers imposed glucose restriction on T cells and dampened thei
164  highly undulating T-cell/APC interface that imposes substantial constraints on T-cell organization.
165 ctively, these data not only show that Cbl-b-imposed constraint on TCR signaling has differential eff
166 ogical ordering constraints on subprocesses, impose prerequisites on temporal regulation and spatial
167 f false detections, depended strongly on the imposed restrictions on temporal precision of detection
168 more, although the molecular mechanisms that impose spatiotemporal constraints on TH action in the br
169 erring slots at presynaptic terminals, which impose a ceiling on the synaptic efficacy of the channel
170       Unfolded and malfolded client proteins impose a stress on the endoplasmic reticulum (ER), which
171 e and conjugate channels, and can inevitably impose an influence on the quantum effects such as entan
172 he surface-adsorbed glycoproteins apparently impose an ordering on the water, resulting in a strong r
173 low levels of antibiotic resistance does not impose any constraint on the ability to evolve high leve
174  Finlay-Darlington (FD) model, FFNN does not impose any constraints on the functional form of the mod
175                                 SCG does not impose any restriction on the size or the number of the
176 ansformation of the IXS data, but a means to impose causality on the data and reconstruct the charge
177 e demand shifts for gasoline and diesel will impose challenges on the ability of the U.S. refining in
178 licated nature of the experiments, and often impose constraints on the data collection process, such
179 was predicted in 01_AE infections, which may impose constraints on the use of CCR5 antagonists in cer
180 kets within this more complete Fermi surface impose constraints on the wavevector of any underlying o
181 , a highly malignant childhood brain tumour, impose debilitating effects on the developing child, and
182                     Folding and function may impose different requirements on the amino acid sequence
183 inment methods are insufficient because they impose evolutionary pressure on the organism to eject th
184 nctional architecture of cerebral cortex may impose fundamental restrictions on the spread of artific
185     The requirements of quantum computations impose high demands on the level of qubit protection fro
186 ernary structural interface is sufficient to impose kinetic stabilization on the entire quaternary st
187 umber of cells that can be assessed and thus impose limitations on the ability to measure heterogenei
188  can be expensive and time-consuming and may impose limits on the sample size.
189 erically hindered and repulse each other and impose mechanical stress on the PDA backbone, resulting
190 isms (checkpoints) exert quality control and impose order on the timing and organization of downstrea
191 spite being extremely beneficial, micropores impose restrictions on the mass transport of reactants,
192                             Our results also impose restrictions on the potential role of atmospheric
193 cient cause interactions, the outcome models impose restrictions on the relation between the confound
194 oth species, chemical mate guarding may also impose selection pressure on the long-range female sex p
195 ity are major sources of image artifacts and impose severe limitations on the effective imaging resol
196                      Such extreme conditions impose significant challenges on the direct observation
197 erson localization and the Imry-Ma argument, impose significant restrictions on the phases of matter
198 location and distances of the stator helices impose spatial restrictions on the bacterial F(o) comple
199 culiarities of electronic structure of xenon impose specific features on the bonding within a perovsk
200 strated to increase rates of cyclization and impose stereochemical constraints on the reactions.
201 us enzymes in the production host, which can impose stress on the host cell and, thereby, limit perfo
202                   We show that these results impose stringent constraints on the dynamics of processe
203  pressure-dependent pair-breaking effect and impose strong constraints on the pairing symmetry of the
204        Interventions that address the stress imposed by alignment on the PF compartments may delay PF
205                        We compared the costs imposed by care on the survival and residual reproductiv
206 tions to overcome conformational constraints imposed by PLB on the N-domain of the Ca-ATPase; alterna
207 enhouse gases alone, the rich group may have imposed climate damages on the poor group greater than t
208  to changes in diets with minimal additional imposed constraints on the model.
209 removal of glycosylation sites from SI/06 HA imposed constraints on the theoretical structure surroun
210 hosts and determined whether these mutations imposed fitness costs on the standard laboratory host.
211                              The tool either imposed forces on the hand or displaced the cursor assoc
212 styrenesulfonate) (PSS) layer onto the AuNRs imposed negative charges on the nanorod surface, and the
213 s of the TSE are performed with restrictions imposed only on the distances between the pairs of resid
214 es, obtained immediately after the motor had imposed stress on the filament, showed steps and pauses.
215 e an RNA genome, suggesting that plants have imposed strict constraints on the evolution of DNA virus
216    This study aims to evaluate the effect of imposed transgene load on the cardiogenic competency of
217 nt deprived of its deubiquitinating activity imposes a halt on the dislocation reaction, as judged by
218                           We argue that this imposes a limit on the relationship between fitness and
219 n laser-driven particle acceleration schemes imposes a limit on the total acceleration achievable in
220                             This requirement imposes a limitation on the imaging speed as digital mic
221 symmetry associated with cyclic competitions imposes a limitation on the resulting coexistence states
222 appropriately regularized, which effectively imposes a prior on the activity profiles.
223 he miniaturization of this concept, however, imposes a restriction on the dimensions of the intercavi
224                         We propose that hAGT imposes a strain on the DNA duplex and searches for DNA
225 onclude that even though the ortho-tBu group imposes additional strain on the starting metallocenopha
226 e antiparallel nature of the parental duplex imposes certain constraints on the activity of the DNA p
227 ve explored the hypothesis that the C region imposes conformational constraints on the variable (V) r
228                                 The symmetry imposes constraints on the ability of the enzyme to opti
229                                In turn, this imposes constraints on the chiral selectivity of the con
230  descendants, and illustrate how development imposes constraints on the evolution of complex phenotyp
231 ment in the context of replication forks and imposes constraints on the mechanism involved.
232 icated that the class I MHC cytoplasmic tail imposes constraints on the molecule's diffusion.
233 We propose that successful speech processing imposes constraints on the self-organization of synchron
234 thography techniques are available, each one imposes different requirements on the types of probes th
235                            DNA helical twist imposes geometric constraints on the location of histone
236 inding of both synaptotagmin and ganglioside imposes geometric restrictions on the initiation of BoNT
237  remained a low-throughput method because it imposes high requirements on the optical quality of samp
238                  Assuming an affine gap cost imposes important restrictions on the realism of the evo
239 ctors and that normally the microenvironment imposes limitations on the types of neurons produced.
240  tunnelling current through grain boundaries imposes limits on the maximum magnetoresistance that can
241       The rapid degradation of blood ex vivo imposes logistical limitations on the utilization of blo
242 rameric enzyme possesses 222 symmetry, which imposes numerous constraints on the single active site p
243 monas killing by the Duox-based system as it imposes oxidative stress on the host.
244             Hence, thymic-negative selection imposes peptide specificity on the mature T cell reperto
245 n, manifested in clustering of key residues, imposes powerful constraints on the conformational space
246 ind that the organization of snowflake yeast imposes powerful limitations on the available space for
247        These results indicate that kinesin-5 imposes restrictions on the growth of the axon and does
248 the largest energy end-use of buildings that imposes significant burden on the society.
249 ic environment of the lipid bilayer membrane imposes significant constraints on the structures and fu
250 ng steady-state microbiota composition as it imposes significant restrictions on the allowable commun
251                     However, miniaturization imposes steep demands on the flight system because small
252 ng and biomechanical evidence that adduction imposes strain on the ONH and peripapillary tissues.
253   However, conventional ratiometric CEST MRI imposes stringent requirements on the selection of CEST
254 stained release of neurotransmitter but also imposes temporal regularity on the release process, part
255 chanism by which such a rare cell population imposes tolerance on the large repertoire of differentia
256 improve the quality of activity inference by imposing a constraint on the minimum spike size.
257                                           By imposing a limit on the proliferative lifespan of most s
258 n can be improved by regularization, i.e. by imposing a structure on the estimate.
259                        On the other hand, by imposing a threshold on the minimum number of links two
260                     This was accomplished by imposing additional forces on the system which ensure th
261 eneous risk profiles in a population without imposing assumptions on the subgroups or method.
262  substantially reduces cold ischemia without imposing constraints on the intestinal transplant.
263 s designed to disincentivize the target from imposing costs on the vengeful individual.
264                               In addition to imposing direct selection on the host to resist these ef
265 that cells probe the TCR-pMHC interaction by imposing force on the interaction.
266   However, if we implement actual control by imposing input signals on the minimum set of driver node
267 d amyloidogenesis under acidic conditions by imposing kinetic stabilization on the entire tetramer.
268                            These function by imposing kinetic stabilization on the native tetrameric
269 se material encounters a target, it expands, imposing mechanical stress on the wire and altering its
270 mply treating all the genes independently or imposing no restriction on the correlations among the ge
271                                              Imposing observational constraints on the terrestrial ca
272 s limited to refining autopodial morphology, imposing pentadactyl constraint on the limb's polydactyl
273 llegitimate signal-independent activation by imposing robust control on the dismissal of corepressors
274 pholipid) molecular species present, thereby imposing severe restrictions on the dynamic range of the
275 iminating against purines at position -3 and imposing steric restraints on the invariant Arg(300).
276 ses, with the population-genetic environment imposing strong directionality on the paths that are ope
277 s of the inducing chemical or treatment, can impose limitations on their use.
278 human induced pluripotent stem cells (iPSCs) impose major limitations on their utility in biomedical
279  branched DNA, yet as a class these proteins impose significant distortion on their target junctions.
280 emonstration that evolved plasmids no longer imposed a cost on their hosts when transferred to a plas
281  effect of aggregation-caused quenching that imposes limitation on their labelling efficiency or conc
282                              DNA flexibility imposes significant constraints on their topology sugges
283 imensional structures of homologous proteins imposes strong constraints on their sequence variability
284  relates to one of these, with the remainder imposing additional constraints on thermodynamic transit
285 rt developed by synthetic chemists trying to impose their will on these reactive species.
286                                           We imposed selection on three populations using label rate
287  the complexity of higher eukaryotic genomes imposes severe limitations on transcript recall and spli
288 his implies that interactions with membranes impose a limitation on transducin translocation.
289 leus and so functions as a molecular ratchet imposing directionality on transport.
290 raises the kinetic barrier for dissociation, imposing kinetic stabilization on TTR and preventing agg
291 themes were the role of extracellular matrix imposing mechanical mechanisms on tumor cell function, i
292 is, suppresses medulloblastoma formation and imposes selective pressure on tumors that form.
293  10 (ND10), the discrete nuclear bodies that impose restrictions on viral expression.
294 rical signals in the retina's photoreceptors impose a limit on visual sensitivity.
295 an impede public trust in drinking water and impose major costs on water utilities.
296 quirements for avoidance of runaway embolism imposed increasing constraints on water transport effici
297 and we propose that it is this property that imposes constraints on which enzymes gain access to the
298 us genes encoding or producing antigens that impose limits on xenotransplantation as they are discove
299 factors is rather common but their stability imposes significant challenges on yield, purity, and pre
300 buffer concentration, and species valence to impose variations on zeta potential, effective mobility,

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