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1 fying the loci contributing to a given trait impractical.
2 in situations where corneal measurements are impractical.
3 haustive searches for structures of interest impractical.
4 m the more intensive infusional regimens are impractical.
5 structure determination may in many cases be impractical.
6 licated models required can make computation impractical.
7 y and conduction, but to date remain largely impractical.
8 monomers makes exhaustive oligomer libraries impractical.
9 administration, but this route is clinically impractical.
10 g all samples upon each new arrival would be impractical.
11 on of all the database networks with a query impractical.
12 ion; but such approaches are computationally impractical.
13 s of thousands of eukaryotic species remains impractical.
14  numbers of sequences in this way is clearly impractical.
15 is uncertain because serial observations are impractical.
16 atalysis on the relevant timescales has been impractical.
17 ade such global studies either impossible or impractical.
18 gs in which ligand isotope-labeling is often impractical.
19 ion makes the synthesis of these biopolymers impractical.
20 s long, directly studying aging in humans is impractical.
21 rated by singlet oxygenation of linloeate is impractical.
22 chine size, and cost have made this approach impractical.
23  virus in every eligible individual would be impractical.
24 r urine collections, but such an approach is impractical.
25 chemical synthesis of complex isoprenoids is impractical.
26 implementing all possible mismatch probes is impractical.
27 ng only cases, when finding good controls is impractical.
28 , especially in settings where microscopy is impractical.
29 exponentially, which renders manual curation impractical.
30 e low throughput, making a genome-wide study impractical.
31 l of the FDR at a preselected level is often impractical.
32 wavelengths such as erbium:YAG are currently impractical.
33 ation of recessive, loss-of-function alleles impractical.
34 t erbium:yttrium-aluminium-garnet fibers are impractical.
35 thermodynamic study of each possible variant impractical.
36 t were previously considered computationally impractical.
37 , but this strategy will become increasingly impractical.
38 s of expression profiling that are currently impractical.
39 nsgenic animals for each gene of interest is impractical.
40 m by use of a conventional congenic approach impractical.
41 n-hospital monitoring to steady state highly impractical.
42 dividual assessment of C-peptide kinetics is impractical.
43 niques developed to identify CD8+ T cell Ags impractical.
44 rocedures are contraindicated or technically impractical.
45 thematically optimal values may sometimes be impractical.
46 ut, purification of cells for every assay is impractical.
47 t current methods for its implementation are impractical.
48 omes for which gene-based linkage mapping is impractical.
49 ndividual variables to predict acute ICH was impractical.
50 t guidelines recommend five to six, which is impractical.
51 e plaque reduction neutralization testing is impractical.
52 n human cellular models have previously been impractical.
53 eologic methodologies are time consuming and impractical.
54 cquisition and processing, but this is often impractical.
55 g drugs soon after infection, which is often impractical.
56 r the direct measurement of these species is impractical.
57 novative; existing definitions are vague and impractical.
58 on is infected, making universal eradication impractical.
59 s is unknown because direct observations are impractical.
60 a for identifying those with sepsis would be impractical.
61 haracterization of epidermal cell parameters impractical.
62 ability, and graft removal by hepatectomy is impractical.
63 mmonly co-occur, making a dualistic approach impractical.
64 ries for riboswitch function in intact cells impractical.
65  system observables which would otherwise be impractical.
66 er systems for which more direct methods are impractical.
67 nical trials to establish the best treatment impractical.
68 he score and LR tests can be computationally impractical.
69        Because total dialysate collection is impractical, an automated method was developed for measu
70  systemic therapy in breast cancer make them impractical and even impossible to conduct.
71 , making repeated imaging of the same animal impractical and potentially affecting lymphocyte behavio
72 mprove adherence have typically been costly, impractical, and at best only minimally successful.
73 ces, exact algorithms become computationally impractical, and progressive algorithms iterating pairwi
74                     Culture for diagnosis is impractical, and seroconversion is often delayed after n
75 nst large numbers of cell lines is currently impractical, and such experiments are often difficult to
76 tandard; however, widespread testing remains impractical, and the development of in vitro assays that
77   However, identifying network hubs is often impractical, and they can be misleading if monitored for
78 reas where replacement feeding is unsafe and impractical are repeatedly exposed to HIV-1 throughout b
79 hown by DFT, the noncoordinating nitrogen is impractical as a base in water oxidation catalysts due t
80 the slow growth habit of B. braunii makes it impractical as a production system.
81 for every combination of observables becomes impractical as the number of dimensions increases.
82 emains the gold standard for diagnosis it is impractical at a population level.
83 se technical hurdles make mutation discovery impractical at low-mutation frequency levels (<10(-2)).
84 the Ru-peroxo bonds, however, is found to be impractical at room temperature, with a barrier of Delta
85 l characterisation of WbmF, WbmG and WbmH is impractical at the present time.
86 tion in the same patient has been considered impractical because of logistics restraints.
87              Not only are prospective trials impractical because of the emergent nature of the issue
88 achievement of target doses in humans proved impractical because of the large number of injections re
89 for conventional fluctuation analysis proved impractical because of the rapid rundown of calcium chan
90  in cases where more advanced methods may be impractical because of their extremely long computationa
91  signal processing is generally deemed to be impractical because optical nonlinearities are usually w
92               Convalescent-phase serology is impractical, blood culture is slow, and many pathogens a
93 sence of homologous human enzymes makes them impractical candidates for drug development.
94                    Donor fasting is probably impractical clinically as a method to improve the donor
95 ne can now approach structures of previously impractical complexity.
96 either fail dramatically, or else can impose impractical computational burdens due to numerical integ
97  modality has been limited by inefficient or impractical delivery systems.
98 he failure of our sedation regimen led to an impractical demand for anaesthesia and unacceptable wait
99 nal antibodies using conventional methods is impractical due to high costs.
100 eezing without nucleation sites, making FTVs impractical due to instrument engineering challenges.
101 typical mammalian cells has been found to be impractical due to the large size of mitochondria relati
102 ividual specimens has proven challenging and impractical due to, in part, a singleplex nature of repo
103 tment's various complications along with the impractical duration and depth of therapy significantly
104 ies are either limited in scope or are of an impractical duration for routine testing.
105                     Column purifications are impractical during procedures involving multi-gigabecque
106 by PTR-ToF-MS, such a procedure could become impractical, especially when standards are not readily a
107 search replicates, but further search proved impractical even with grid computing.
108 d description of the solvent, which would be impractical for all conformations and sites sampled in t
109 ributions in density make these microspheres impractical for applications demanding small steps in de
110 examinations are costly, time-consuming, and impractical for assessing population-level needs.
111 osing is recommended for children in VF, but impractical for automated external defibrillator (AED) u
112  observed in nature, yet current methods are impractical for characterizing the molecular basis and f
113 lantation is required, making such protocols impractical for clinical application.
114 onics and microelectromechanical systems, is impractical for defining feature sizes below 0.1 microme
115                However, long-term storage is impractical for Drosophila, so mutant strains must be ma
116 el for hepatitis C virus (HCV) infection, is impractical for early stage testing of HCV vaccine candi
117 standard test statistics are computationally impractical for even moderate-sized genome-wide associat
118 lassical mutagenesis in mice is logistically impractical for generating deletion sets on a genome-wid
119 f the target cells will be too expensive and impractical for global application.
120                         This makes their use impractical for high throughput drug discovery platforms
121 , but it leads to long runtimes that make it impractical for large count data common in bioinformatic
122 putationally intensive MCMC methods that are impractical for large datasets.
123 on phylogenetic evidence has previously been impractical for large numbers of genomes at once, due to
124 tides covering the whole protein sequence is impractical for large proteins.
125  low-throughput technique, making it largely impractical for large-scale measurements such as cell ty
126 gnetic resonance imaging, while accurate, is impractical for large-scale observational studies.
127 l phononic crystals, but Bragg scattering is impractical for low-frequency wave control because of th
128 mperatures (more than about 1,300 kelvin) is impractical for many applications.
129 ) has been the gold standard approach but is impractical for many clinical laboratories and is often
130 n the order of tens of thousands that can be impractical for many diseases or may lower the quality o
131                 This procedure is clinically impractical for many patients with pulmonary fibrosis, a
132  positron emitter carbon-11, which is rather impractical for many PET centers.
133 on emitted spreads along a "cone", making it impractical for most applications.
134 loading of typically <1 wt.%, which is often impractical for most clinical applications.
135  intake make an exclusively plant-based diet impractical for most individuals unless fortified foods
136 rate false alarms, such predictions would be impractical for most modern industrialized cities.
137 ire significant manual intervention, and are impractical for multiple genomic datasets in high-throug
138  kinetic information in most buffers but was impractical for NO analysis in proteinaceous media.
139 g the available diagnostic methods, many are impractical for point-of-care field testing.
140 electivities without parametrization but are impractical for predicting small changes in selectivity.
141 s confirmed, that shorter devices are rather impractical for production sequencing applications when
142 ccuracy of base-calls on these platforms are impractical for production use due to their computationa
143 ent bisulfite sequencing platforms make them impractical for quantifying locus-specific RE methylatio
144  are optically driven with lasers, which are impractical for quantum computing owing to the bulk and
145 cially for recently infected animals, or are impractical for rapid field diagnostic applications.
146 t with recombination has conventionally been impractical for regions beyond tens of megabases.
147  scale, this is both very time-consuming and impractical for repeated explorations with standard mark
148 d molecules is computationally expensive and impractical for routine NMR-restrained calculations that
149 served loci) and whole-genome sequencing are impractical for routine use.
150 ng of individual 2D TMD layers, which remain impractical for scaled-up applications.
151 ristic of lipid I renders MurX enzyme assays impractical for screening and lacks reproducibility of t
152 f stem cells within the adult CNS makes them impractical for surgical removal and autologous transpla
153  for examining one gene at a time, it can be impractical for surveying the large genomic intervals co
154 on whole-genome deep sequencing is currently impractical for the purpose of routine clinical care.
155 g wires for signal transduction, but this is impractical for the readout of individual nanoparticles.
156 g germination of superdormant spores but are impractical for use in a hospital setting, where Clostri
157 nd other well-recognized limitations make it impractical for widespread use given the overall NAFLD d
158 ls without rotating the sample, which can be impractical, for instance for samples held in a cryostat
159 plete transduction of the entire heart is an impractical goal, it becomes critical to determine the m
160 g these newer approaches are inconclusive or impractical, however, catheter-based techniques are stil
161 deliver such coverage can be undesirable and impractical; however, endangered populations are increas
162 dy of lymphoid phenotypes can be obscured or impractical if homozygous mutations cause early embryoni
163 al connectivity from functional connectivity impractical; (ii) that indirect connections and interreg
164 us observation of livestock by farm staff is impractical in a commercial setting to the degree requir
165                           It will clearly be impractical in acids that are weaker still.
166  cooling, which is generally inefficient and impractical in clinical situations.
167  over hundreds of shots, which is ordinarily impractical in conventional shock tube studies.
168 tology and require multiple visits have been impractical in developing countries.
169 y approaches to the management of aflatoxins impractical in developing-country settings, but the stra
170 ormously computation-time intensive and thus impractical in high throughput studies, informatics-base
171 eview for confirmation of an RA diagnosis is impractical in large cohort studies, the current study (
172  However, such specification is difficult or impractical in many scenarios.
173  identify the absence of body iron stores is impractical in most cases.
174 ovision of sanitation and water treatment is impractical in most developing countries, where morbidit
175                    Mammographic screening is impractical in most of the world where breast cancers ar
176 n academic departments of psychiatry that is impractical in primary care settings because it takes to
177 tal for antibiotic treatment, which is often impractical in resource-limited settings.
178 tal for antibiotic treatment, which is often impractical in resource-limited settings.
179 primary method for gene cloning, but this is impractical in several situations, for example, when the
180      DFT optimization of H atom positions is impractical in structural biology studies.
181 ndicates that a 1 km screening radius may be impractical in such resource limited settings such as Sw
182 ost most of these research regimens would be impractical in the clinical setting.
183 tery but its instability towards Na makes it impractical in the Na-O2 battery.
184 observations of early pretumor mutations are impractical, it may be possible to retrospectively recon
185 B(NDippCH)2} (1, Dipp = 2,6-iPr2C6H3) render impractical its use for the direct introduction of the {
186 accination against the toxin undesirable and impractical, leading to intensified efforts to develop e
187 onses into strong signals so that ordinarily impractical measurements become possible.
188 nical practice and research studies is often impractical, necessitating short-item if not single-item
189         Moreover, simulations reveal that an impractical number of 1-ha field plots (from 10 to more
190 herapy when other anaplerotic substrates are impractical or contraindicated, e.g. in propionic acidem
191 tions when existing genome-based methods are impractical or ineffective.
192 s as well as to perform experiments that are impractical or not feasible in vivo or in vitro.
193 tically ill patients have been assumed to be impractical or not feasible.
194 ical point of care, instrumentation might be impractical or unavailable.
195  there are many circumstances in which it is impractical or undesirable to insert objects or subjects
196 ration step prior to mass analysis is either impractical or undesirable.
197 e high-resolution NMR is either unnecessary, impractical, or both, as is the case in the emerging fie
198  nutritional exposures are often impossible, impractical, or unaffordable.
199             Mitigating therapies, aside from impractical organ transplantation, remain limited and th
200 DNA sequence from sub-nanogram quantities is impractical owing to inefficient delivery of DNA molecul
201  modification of the human genome in vivo is impractical owing to the low frequency of homologous rec
202 s for clinical use as combination therapy is impractical, owing to regulatory hurdles and cost.
203 icles and alpha-like nuclei have so far been impractical, owing to the exponential growth of the numb
204                              Mortality is an impractical primary endpoint for clinical trials in pati
205        However, this approach often requires impractical reagents, such as IOAc, or strong co-oxidant
206  contributing to a specific phenotype may be impractical, region-specific saturation screens that pro
207   Perhaps the most important obstacle is the impractical requirement of multiple blood samples to ade
208  bandwidth of operation because they require impractical sizes and masses.
209 t nonlinear ultrasonic methods still involve impractical solutions such as cumbersome signal calibrat
210 traps limit the speed of such detectors, and impractical strategies, e.g., the use of large gate-volt
211 in circumstances where liquid lubricants are impractical, such as in space technology, ultra-high vac
212                              The complex and impractical techniques for the measurement of GFR have l
213 ll line facilitates the following previously impractical techniques: high-throughput screening for ag
214 tives and exposes some alternatives to be so impractical that they are almost fraudulent.
215 ry path for long decision sequences is often impractical; thus, cognitive shortcuts are often essenti
216 ni and false discovery rate (FDR), are often impractical to apply, as a majority of the causal varian
217 of elderly adults are limited, because it is impractical to conduct repeated nitrogen balance protoco
218 ergy landscape that would be computationally impractical to do via Molecular Dynamics.
219 far smaller than the total population, it is impractical to exhaustively characterize diversity of mo
220 until now it has been difficult, costly, and impractical to fabricate such nanowires in proper alignm
221  to those of standards; however, it is often impractical to have standards on hand for every compound
222 red to complete the immunizations, making it impractical to limit an acute epidemic.
223  resources available, but it quickly becomes impractical to manually access and review all of these s
224 nsiveness to inhaled corticosteroids but are impractical to measure in primary care.
225 r (PM) component of HAP, but it is currently impractical to measure personal exposure to PM in large
226 ible to test hypotheses that were previously impractical to model.
227                As a consequence, it has been impractical to obtain accurate thickness estimates for t
228                 Although tissue biopsies are impractical to perform routinely in the majority of pati
229 ng a library of >50 macrolides that would be impractical to produce by chemical methods.
230 osition component that remains difficult and impractical to quantify by most investigators outside of
231                                  Since it is impractical to screen all possible drug combinations for
232 cies of risk alleles in tissue banks make it impractical to study their function in cells derived fro
233                                Because it is impractical to test each molecule/labyrinth pair using c
234 sments consider multiple stressors but it is impractical to test every chemical combination to which
235 onances whose short relaxation times made it impractical to use nuclear Overhauser effect (NOE) measu
236 ike clinical trials for exudative AMD, it is impractical to use the change in visual acuity (VA) as a
237  new and standard cut-points, which makes it impractical to use the new ones on a population that inc
238  Room-temperature sodium metal batteries are impractical today because morphological instability duri
239 derstanding of candidal pathogenesis, but is impractical using existing techniques.
240 high sensitivity and specificity, but IFA is impractical, variably reproducible, and cumbersome for l
241 ive exon usage (AEU) using such data require impractical visual inspection and still yield high false
242          Because long-term field studies are impractical, we used known behavior of male and female G
243 gh charge carrier mobilities but are usually impractical, whereas polymers have good processability b
244 anodiamonds under vacuum may make the method impractical with currently available materials.
245 ogistics render 2-dose immunization regimens impractical would be a major advance.PXVX0200, based on

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