ライフサイエンスコーパス: imprinting control region

1 of DNA methylation at the germ-line-derived imprinting control region.

2 independent of the CTCF-binding sites in the imprinting control region.

3 nded on functional CTCF binding sites in the imprinting control region.

4 tes at mammalian c-myc promoter and H19/Igf2 imprinting control region.

5 howed nearly complete methylation in the H19 imprinting control region.

6 f2, and Ins2 genes that share a bifunctional imprinting control region.

7 tely regulated by shared DNA elements called Imprinting Control Regions.

8 ions that have been confirmed to function as imprinting control regions.

9 ment and DNA methylation of the H19 and Gtl2 imprinting control regions.

10 ly delineate the boundaries of several known imprinting control regions.

11 ith the exception of certain loci, including imprinting control regions.

12 hibit distinct methylation patterns at their imprinting control regions.

13 Lysine 4 and lysine 9 trimethylation marks imprinting control regions.

14 9, KvDMR1, Snrpn promoter/exon 1, and IG-DMR imprinting control regions.

15 decrease in methylation at the H19 and Snrpn imprinting control regions.

16 ific interactions occur between the IGF2/H19 imprinting control region-1 (ICR1) and ICR2, a region wh

17 promoter, which unlike such sites in the H19-imprinting control region and X chromosome, is insensiti

18 tion, nucleosomes reconstituted onto the H19 imprinting control region are more accessible.

19 LAGL1, INPP5F transcript variant 2, and PEG3 imprinting control regions are not methylated in the mac

20 In addition to 11ZF-binding paternal imprinting control regions, cancer-testis gene promoters

21 on upstream of H19 (H19-DMR), serving as the imprinting control region, determines the reciprocal exp

22 parental chromatin becomes equalized and how imprinting control regions escape from this reprogrammin

23 thylated region 2 (DMR2) of IGF2 and the H19 imprinting control region (H19 ICR) compared with term i

24 The 2.4-kb H19 imprinting control region (H19ICR) is required to establ

25 ryonic days 14.5 (eight dams and 58 fetuses; imprinting control region ICR strain) and 17.5 (21 dams

26 A paternally methylated imprinting control region (ICR) directs allele-specific

27 ymai at the syntenic mouse locus is a likely imprinting control region (ICR) for the approximately 12

28 The H19 imprinting control region (ICR) functions as a CTCF-depe

29 s to the unmethylated maternal allele of the imprinting control region (ICR) in the Igf2/H19 imprinti

30 that localized DNA demethylation at the H19 imprinting control region (ICR) induced by 5-AzaCdR, red

31 The DNA methylation state of the H19/Igf2 imprinting control region (ICR) is differentially set du

32 n the case of the imprinted H19 gene, a 2 kb imprinting control region (ICR) is subject to differenti

33 The most conserved characteristic in the imprinting control region (ICR) is the presence of multi

34 Paternal deletion of the imprinting control region (ICR) KvDMR1 results in loss o

35 distal chromosome 7 is regulated by a 2.4-kb imprinting control region (ICR) located upstream of the

36 inate from several kilobases upstream of the imprinting control region (ICR) of the domain, from a pr

37 , the zinc-finger protein CTCF, binds to the imprinting control region (ICR) of the genes Igf2 (encod

38 the insulin-like growth factor 2 (Igf2)/H19 imprinting control region (ICR) on chromosome 7 colocali

39 To evaluate models for how this imprinting control region (ICR) regulates imprinting, we

40 A approximately 2.4-kb imprinting control region (ICR) regulates somatic monoal

41 Hyper- and hypomethylation at the IGF2-H19 imprinting control region (ICR) result in reciprocal cha

42 dependent on the presence of an intervening imprinting control region (ICR) situated 2 kb upstream o

43 The imprinting of Igf2 is dependent upon an imprinting control region (ICR) that lies 90 kb 3' of th

44 addition, we found normal methylation of an imprinting control region (ICR) that regulates H19 and I

45 ed by allele-specific DNA methylation at the imprinting control region (ICR), but the underlying mech

46 at the H19 regulator region encompassing the imprinting control region (ICR), concomitant with increa

47 Using the mouse Igf2/H19 imprinting control region (ICR), Igf2r differentially me

48 19 gene are regulated by an intervening 2 kb imprinting control region (ICR), which displays parentsp

49 g a mutant mouse line lacking this potential imprinting control region (ICR).

50 are regulated by a differentially methylated imprinting control region (ICR).

51 9 locus, including the paternally methylated imprinting control region (ICR).

52 rs, epigenetically modified silencers and an imprinting control region (ICR).

53 or 2 (Igf2) and H19 genes is regulated by an imprinting control region (ICR).

54 Selective methylation of CpG islands at imprinting control regions (ICR) determines the monopare

55 n the germline methylation at this putative "imprinting control region" (ICR).

56 decrease in methylated cytosines that act at imprinting control regions (ICRs) and meiotic genes (sta

57 ion at non-CpG islands within these regions, imprinting control regions (ICRs) and secondary differen

58 Imprinting control regions (ICRs) are known to repress g

59 Clusters of imprinted genes are regulated by imprinting control regions (ICRs) characterized by DNA m

60 Two candidate imprinting control regions (ICRs) have been identified a

61 n also changed the methylation levels at the imprinting control regions (ICRs) of these domains in a

62 of several imprinted domains, including the imprinting control regions (ICRs) of Xist, Peg3, H19/Igf

63 Imprinting control regions (ICRs) often harbor tandem ar

64 Silencing is brought about by imprinting control regions (ICRs) that are differentiall

65 Mammalian genomic imprinting is regulated by imprinting control regions (ICRs) that are usually assoc

66 ted the sequences of the mouse and human H19 imprinting control regions (ICRs) to see whether they co

67 Additionally, all the known imprinting control regions (ICRs) were classified into g

68 d epigenetically at discrete elements termed imprinting control regions (ICRs) with their parental or

69 Remarkably, H4R3me2s is mono-allelic at imprinting control regions (ICRs), at which it marks the

70 These genes are regulated by imprinting control regions (ICRs), cis-regulatory elemen

71 P57 in the maintenance of DNA methylation at imprinting control regions (ICRs), revealing an allele-s

72 e heart of genomic imprinting in mammals are imprinting control regions (ICRs), which are the discret

73 ulated by allele-specific DNA methylation at imprinting control regions (ICRs).

74 s highly enriched in the inactive alleles of Imprinting Control Regions (ICRs).

75 ining the DNA methylation memory at multiple imprinting control regions in early mouse embryos and em

76 The methylation status of the H19- and Snrpn-imprinting control regions in germ cell clones parallele

77 the SET7/9 histone methyltransferase to the imprinting control regions, inhibiting production of an

78 The PWS imprinting control region is the promoter for a one mega

79 1 lowered 24 h nonfasting glucose levels in imprinting control region mice on a high fat diet with d

80 The methylation pattern of the imprinting control region of chromosome 11p15.5 and ABCC

81 CpG methylation within the promoter and the imprinting control region of MEG3 gene in meningiomas.

82 In the current study, the imprinting control region of the mouse Peg3 domain was d

83 entae, however, displayed hypomethylation of imprinting control regions of select imprinted genes and

84 According to the results, the Imprinting Control Regions of the PEG3, MEST and GNAS do

85 The ICR (Imprinting Control Region) of the Peg3 (Paternally Expre

86 PWS/AS locus on 15q11-q13 is regulated by an imprinting control region that is maternally methylated

87 genes and the methylation profiles of three imprinting control regions to assess the epigenetic stat

88 w DNA methyltransferases are targeted to the imprinting control regions to initiate and maintain DNA

89 methylated region is an additional principal imprinting control region, which directs Gnas methylatio

90 l-specific methylation at KvDMR1, a putative imprinting control region within intron 10 of the KCNQ1

91 alities, including the methylation status of imprinting control regions within imprinted gene cluster