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1  interacts with the BR receptor BRI1 in vivo in a BR-independent manner.
2 omes and ProP concentrated at the cell poles in a CL-independent manner.
3 at SUMO-conjugated DELLA binds to this motif in a GA-independent manner.
4 ed receptor to block skeletal muscle atrophy in a GH-independent manner.
5  although Tdp1 was recruited to only 5' DSBs in a Ku-independent manner.
6 de channels and transporters in living cells in a pH-independent manner.
7 MAD2 signaling promotes male differentiation in a RA-independent manner.
8 e gene promoter is activated by the pathogen in a SA-independent manner.
9  polyribosomes to increase protein synthesis in a CAP-independent manner.
10 ne (m(6)A) in their 5' UTR can be translated in a cap-independent manner.
11 y sites (IRESs) promote translation of mRNAs in a cap-independent manner.
12 s released upon DNA damage and is translated in a CAP-independent manner.
13 itiating the translation of viral late mRNAs in a cap-independent manner.
14 e productively infected with cell-free HIV-1 in a CD4-independent manner.
15 assays, these peptides inhibited HIV-1 entry in a CD4-independent manner.
16 ted from the X even before the 30-cell stage in a DCC-independent manner.
17 served modulation is AhR specific and occurs in a DRE-independent manner.
18 lutathionylation during ischemia-reperfusion in a GSH-independent manner.
19 tes accumulate in the leaf abaxial epidermis in a GTR-independent manner.
20 f Cyclin D1 and decreased cell proliferation in a HIF-independent manner.
21 complex 1 (mTORC1) activation by amino acids in a HIF-independent manner.
22 ccumulation was induced by Siglec-8 ligation in a MEK-independent manner.
23 receptor (HER) kinase activation proliferate in a MEK-independent manner.
24 duces apoptosis mediated by the receptor DCC in a p53-independent manner.
25 inhibits the mitochondrial apoptosis pathway in a p53-independent manner.
26 ectal cancer cells with hemizygous TP53 loss in a p53-independent manner.
27  of CDK1 and cyclin B1 and activation of p21 in a p53-independent manner.
28 xia telangiectasia-mutated kinase) signaling in a p53-independent manner.
29 ediated by the BH3-only domain protein, Bik, in a p53-independent manner.
30 e whether RPS14 regulates cell proliferation in a p53-independent manner.
31  p14(ARF) is capable of triggering apoptosis in a p53-independent manner.
32 scription factor c-Jun onto the ARF promoter in a p53-independent manner.
33 ssion of Mdm2 results in genomic instability in a p53-independent manner.
34 nd cerebellar granule neuron precursor cells in a p53-independent manner.
35 evels also increased cellular transformation in a p53-independent manner.
36 PAN, NPM, and BAX to guarantee cell survival in a p53-independent manner.
37  in the presence of phosphorylated eIF2alpha in a PKR-independent manner.
38 in increased activation of the inflammasome, in a PKR-independent manner.
39  components such as Importin beta and Nup153 in a PP1-independent manner.
40 not inhibit LTP, whereas fibrils inhibit LTP in a PrP-independent manner.
41 licing isoforms of BRAF(V600E) that dimerize in a RAS-independent manner.
42 at Mps1 inhibits sister chromatid separation in a SAC-independent manner.
43 romosome and harbor more long-range contacts in a sex-independent manner.
44 OD 4.3) was found to influence aortic strain in a sex-independent manner.
45 , YkuE can also be targeted to the cell wall in a Tat-independent manner.
46 esponding to a remarkable array of cytokines in a TCR-independent manner.
47 ate that ABA is a prosurvival factor for Mks in a Tpo-independent manner.
48 intracellularly expressed IgG Fc is degraded in a VCP-independent manner.
49 mour suppressor in the intestinal epithelium in a Wnt-independent manner.
50 c as a cofactor, it also was induced by iron in a Zur-independent manner.
51 At this stage, CXCR5 appears to be expressed in a Bcl6-independent manner.
52 tion of HIV-1, also prevents virion assembly in a BST2-independent manner.
53 sensory neurons of Xenopus commonly function in a cAMP-independent manner.
54 ecific EP interactions via chromatin looping in a CTCF-independent manner.
55  transcription is completed in the cytoplasm in a DBR1-independent manner.
56 s it to the damaged DNA after UV irradiation in a DDB2-independent manner.
57 l calcium in turn activates IMM constriction in a Drp1-independent manner.
58 ction of MAVS with caspase-8 on mitochondria in a FADD-independent manner.
59 e proteins Atrx and Daxx associate with H3.3 in a Hira-independent manner.
60 y, dUTX mutations also affect H3K4me1 levels in a JmjC-independent manner.
61 vation and abnormal centrosome amplification in a Pak1-independent manner.
62 n of AD-related cytokines from keratinocytes in a PAR2 independent manner.
63 ather than on chromatin and that this occurs in a PCNA-independent manner.
64 tion of the Akt/SGK cardioprotective pathway in a PI3K-independent manner.
65 is required for high levels of transcription in a PTGS-independent manner.
66 SC23766 affects the levels of neuronal pCREB in a Rac1-independent manner.
67 t FtsN initially localizes to division sites in a SPOR-independent manner.
68 genes, which are vital for immune responses, in a TAF1-independent manner.
69 der kinetic control and affords up to 95% ee in a time-independent manner.
70  poly-G ODN was mediated through CD8 T cells in a TLR9-independent manner.
71 nhibited CD4(+) and CD8(+) T cell activation in a Treg-independent manner.
72 s serine and edits seryl adenylate (Ser-AMP) in a tRNA-independent manner.
73 R signaling and B cell survival are impaired in a BclxL-independent manner.
74   Thus, CC2D1A may also affect HIV-1 budding in a CHMP4-independent manner.
75 es miR-10a maturation by binding pre-miR-10a in a DICER-independent manner.
76  to produce single-stranded secondary siRNAs in a Dicer-independent manner.
77 lso stimulates FANCI monoubiquitination, but in a FANCL-independent manner.
78 n that inhibits the generation of Th17 cells in a Foxp3-independent manner.
79 mer interface inhibits IN enzymatic activity in a LEDGF-independent manner.
80 from compartments other than the chloroplast in a light-independent manner.
81  input resistance from falling to low levels in a light-independent manner.
82 including mammals) regulate circadian timing in a light-independent manner.
83 zyme activation and maturation of IL1beta/18 in a LUBAC-independent manner.
84 nd non-nucleoside/nucleotide inhibitor sites in a metal-independent manner.
85 patterns over a broad range of length scales in a model-independent manner.
86 in-plane orientational correlation functions in a model-independent manner.
87 fectious properties of the resulting fibrils in a polyQ-independent manner.
88 V treatment induced mitochondrial biogenesis in a SirT1-independent manner.
89 ix protein expression by cardiac fibroblasts in a Smad3-independent manner.
90 ations were associated with better prognosis in a stage-independent manner.
91 a, and IL-5 and IL-13 expression in the lung in a STAT6-independent manner.
92 hacin augmented allergic airway inflammation in a STAT6-independent manner.
93 G98P) caused constitutive channel activation in a STIM1-independent manner.
94 ignaling node at newly formed adhesion sites in a talin-independent manner.
95 at are capable of rescuing stalled ribosomes in a tmRNA-independent manner.
96 ves translation of viral structural proteins in a factor-independent manner.
97  that PAK4 protects RhoU from ubiquitination in a kinase-independent manner.
98 o-factor to transactivate FOXM1 target genes in a kinase-independent manner.
99 protects Par6B from proteasomal degradation, in a kinase-independent manner.
100 nsformed colonic and breast epithelial cells in a ligand-independent manner.
101  that spontaneously transforms NIH 3T3 cells in a ligand-independent manner.
102 ven tumor growth because HER2 activates HER3 in a ligand-independent manner.
103 qually to an NF-kappaB reporter in 293 cells in a ligand-independent manner.
104 omes and directly interacts with the beta2AR in a ligand-independent manner.
105 , while Nrp2b also promotes CZ targeting but in a Sema3D-independent manner.
106 ive prediction of compound efficacy in vitro in a system-independent manner.
107 s the production of TNF-alpha by macrophages in a contact-independent manner.
108 lation of the function of isolated platelets in a contact-independent manner.
109 els that respond to both cooling and heating in a DeltaCp-independent manner.
110 , with VAV1 mediating Rho activation by JAKs in a Galphai-independent manner.
111 uminal progenitors that can form 3D colonies in a hormone-independent manner.
112 , activated HIF2alpha-mediated transcription in a hypoxia-independent manner.
113 ypoxia-inducible factor (HIF)-1alpha pathway in a hypoxia-independent manner.
114 preferentially binds to polyubiquitin chains in a linkage-independent manner.
115 ion of RhoA and actomyosin dynamics in VSMCs in a mitosis-independent manner.
116 a range of MHC-I molecules with low affinity in a peptide-independent manner.
117 andem BRCT domain of BRCA1, but surprisingly in a phospho-independent manner.
118 ally set the strength of inhibitory synapses in a release-independent manner.
119 ed by membrane-delimited Gbetagamma subunits in a voltage-independent manner.
120 of eIF2B cofractionates with lipid membranes in a YBR159W-independent manner.
121 mic endosomes, and is delivered to endosomes in a clathrin-independent manner.
122 uman hepatoma cells restricted HCV infection in a genotype-independent manner.
123 47 and it coincided with reduced sociability in a genotype-independent manner.
124 the expression and promoter activity of VMP1 in a Hedgehog-independent manner.
125  attenuated, leading to increased resistance in a mutation-independent manner.
126 t Snf1 and adenylate cyclase (Cyr1) interact in a nutrient-independent manner.
127  utilize bleb formation to indent the matrix in a protease independent manner.
128 ce for double strand-single strand junctions in a sequence independent manner.
129 posons is mobilized exclusively to telomeres in a sequence-independent manner.
130 157(70-893) binds to nucleic acids, although in a sequence-independent manner.
131 ration into the hydrophobic core of proteins in a sequence-independent manner.
132 hodiester backbones induce TLR9 dimerization in a sequence-independent manner.
133 lar helical filaments on double-stranded DNA in a sequence-independent manner.
134 ms a winged helix domain (WHD) and binds DNA in a sequence-independent manner.
135 osphate to the 3'-hydroxyl of RNA substrates in a template-independent manner.
136 A in vivo and for inhibiting cellular growth in a catalytic-independent manner.
137                   However, assembly proceeds in a chaperone-independent manner.
138 es itch and nociceptive sensations in humans in a histamine-independent manner.
139 n but induces CPDs by energy transfer to DNA in a radiation-independent manner.
140 e, NPC components influence genome functions in a transport-independent manner.
141 ces proteasome-mediated degradation of PICT1 in a ubiquitin-independent manner.
142 motes its degradation through the proteasome in a ubiquitin-independent manner.
143 crotubules (MTs) are nucleated and organized in a centrosome-independent manner.
144 gged1 may represent a target for DMD therapy in a dystrophin-independent manner.
145 l maturation step of the small subunit rRNA, in a nucleotide independent manner.
146 tion with membranes, Arl2 binds to membranes in a nucleotide-independent manner.
147 ct K-Ras4B from negatively charged membranes in a nucleotide-independent manner.
148 ed BRAF(V600E)-induced senescence phenotypes in a PARylation-independent manner.
149 he interaction results in degradation of A3A in a proteasome-independent manner.
150 upports transcription and cell proliferation in a bromodomain-independent manner.
151             In contrast, HDAC1 inhibits HSF1 in a deacetylase-independent manner.
152 thway component stabilizing the GLI1 protein in a demethylase-independent manner.
153 on and enhanced transcription by CLOCK-BMAL1 in a demethylase-independent manner.
154 ing that FIH-1 negatively regulates glycogen in a hydroxylase-independent manner.
155 ing that Dnmt3a may inhibit their expression in a methylation-independent manner.
156 tone variant H3.3 at heterochromatic regions in a replication-independent manner.
157 reased synaptogenesis by the remaining axons in a transmission-independent manner.
158 predict aggressive disease in human patients in a proliferation-independent manner.
159 that drive multiple oncogenic translocations in a transcription-independent manner.
160 ets" (ENDs) that condense in the nucleoplasm in a transcription-independent manner.
161 cholamine synthesis, was increased by stress in a glucocorticoid-independent manner.
162                PAT inhibition by CMMC occurs in a brassinosteroid-independent manner.
163 ereas desumoylation by Ulp1 destabilizes Smo in a phosphorylation independent manner.
164 and thus most likely interacts with partners in a phosphorylation-independent manner.
165 e of recruiting and ubiquitinating cyclin D1 in a phosphorylation-independent manner.
166 xpression of antibiotic biosynthetic enzymes in a phosphorylation-independent manner.
167 g gene expression during DNA damage response in a transactivation-independent manner.
168 ochondria and regulates cellular respiration in a transcriptional-independent manner.
169 s, is able to induce a prometastatic program in a transcriptionally independent manner.
170              In this context, CD55 functions in a complement-independent manner and required lipid ra
171 igen recognition triggers effector functions in a diapedesis-independent manner and is inhibited by t
172 ssion of EphA2 promoted stem cell properties in a kinase-independent manner and increased Sox2 expres
173 onfirmed that PIM1 can phosphorylate AR S213 in a ligand-independent manner and cell type-specific ph
174        We also found that SPEN binds ERalpha in a ligand-independent manner and negatively regulates
175 EROID INSENSITIVE1-ASSOCIATED KINASE1 (BAK1) in a ligand-independent manner and positively regulated
176               IOS1 also associated with BAK1 in a ligand-independent manner and positively regulated
177 otif, which targets syntaxin 4 basolaterally in a munc18c-independent manner and second, it allows fo
178                FlhG interacts with FliM/FliY in a nucleotide-independent manner and activates FliM/Fl
179      Origin-distal regions were resegregated in a ParABS-independent manner and instead likely rely o
180  We show that beta-TrCP1 interacts with SMRT in a phosphorylation-independent manner and cooperates w
181 lity and invasiveness of breast cancer cells in a proliferation-independent manner and that this func
182 , were upregulated after resistance exercise in a rapamycin-independent manner and may play a role in
183 t time that this DSP domain acts as a ligand in a RGD-independent manner and is involved in intracell
184 anscriptional complexes with PAX3 and NKX2-1 in a sequence-independent manner and exacerbates their r
185  of gold by a single DNA molecular regulator in a sequence-independent manner and its applications in
186  viRNAs, are transgenerationally transmitted in a template-independent manner and work in trans to si
187 ) adhesions form at the protruding cell edge in a tension-independent manner and are comprised of int
188                       Notably, menthol acted in a voltage-independent manner and reduced the mean ope
189                              Hsp20 binds AC9 in a Yotiao-independent manner and deletion of AC9 decre
190  of PKARIalpha, RSK1 regulates PKAc activity in a cAMP-independent manner, and PKARIalpha by associat
191 olved the ERK1/2 signaling pathway, occurred in a contact-independent manner, and was partially media
192 p1 is in dynamic equilibrium on mitochondria in a fission-independent manner, and that fission factor
193 ch1 signaling, control cardiac morphogenesis in a Notch1-independent manner, and regulate cardiac pro
194 lly activated during this ER stress response in a p53-independent manner, and is an essential mediato
195 r, PRIMA-1(Met) increased expression of NOXA in a p53-independent manner, and NOXA silencing decrease
196 inated prostate cancer liver micrometastases in a proliferation-independent manner, and these pathway
197 tion of Rac1, PI3K/AKT and MEK/ERK signaling in a PTEN-independent manner, and promoted cell and tumo
198 romo-cAMP (8Br-cAMP) acutely to activate PKA in a receptor-independent manner, and cardiac hemodynami
199 alis, the CTD is cleaved off by PorU sortase in a sequence-independent manner, and anionic lipopolysa
200 ely redundant, as active Arg drives invasion in a STAT3-independent manner, and upregulates MMP-3 and
201 elopment of nTh1 cells that express IFNgamma in a Tbet independent manner, and whose expansion can be
202 esponse is regulated by type I IFN and IL-18 in a TCR-independent manner, and IFN-gamma secreting gam
203 ng vascular tubes and beating cardiomyocytes in a fusion-independent manner; approximately 40% of fet
204 forming activity and activated the PDGFbetaR in a ligand-independent manner as a consequence of bindi
205 europrotective peptide revealed that it acts in a sequence-independent manner as an open-channel NMDA
206  B radiation (280-320 nm) initiates melanoma in a pigment-independent manner associated with direct u
207 networks by inducing c-Jun expression which, in a phosphorylation-independent manner, binds to the Ma
208 n (MBP), is hydrolyzed by the 26S proteasome in a ubiquitin-independent manner both in vitro and in m
209 activates PPARgamma transcriptional activity in a ligand-independent manner, but the mechanism for th
210 he expression of RTKs is controlled by Pim-1 in a cap-independent manner by controlling internal ribo
211 t when mature unit-sized crRNAs are provided in a Cas6e-independent manner by transcription terminati
212          CD8+, DN, and Tr1 Treg can also act in a contact-independent manner by elaborating soluble i
213 ex contributes to transcriptional regulation in a CTCF-independent manner by colocalizing with master
214 ound that MUF1 is degraded in the proteasome in a Cul5-independent manner by RhoBTB3-Cul3 ubiquitin l
215 -derived growth factor receptor (PDGFR) beta in a ligand-independent manner by transmembrane helix-he
216                  In addition, UBR5 functions in a ligase-independent manner by prompting protein/prot
217 a alteration of the intestinal microbiota or in a microbiota-independent manner by direct interaction
218 f the brain activation patterns was examined in a model-independent manner by comparing the distribut
219 hyper-tyrosyl phosphorylation is facilitated in a phosphatase-independent manner by enhanced Src recr
220  ischemic myocardium activates PKC signaling in a receptor-independent manner by releasing a persiste
221    H3.3-containing nucleosomes are assembled in a replication-independent manner by means of dedicate
222 lator) complex] represses gene transcription in a sequence-independent manner by spreading along nucl
223 n to being store-operated, is also activated in a store-independent manner by 2-aminoethyldiphenyl bo
224               Ca(2+) entry is also increased in a store-independent manner by arachidonate-regulated
225 pharmacology of ligands can be characterized in a system-independent manner by their affinity for a p
226 a voltage-dependent manner) and inhibits it (in a voltage-independent manner) by binding to different
227  pelvis, the proximal element that is formed in a Shh-independent manner, displayed complementary def
228 d to the leucine-rich repeat domain of NLRP3 in a kinase-independent manner downstream of the inducti
229 mming from E. coli fermentation can continue in a growth-independent manner during nitrogen limitatio
230 tivity modulated TGF-beta1-dependent actions in a SMAD-independent manner, enhanced actomyosin remode
231 senses DNA damage, binds double-stranded DNA in a sequence-independent manner, facilitates processing
232                 This system can be activated in a convertase-independent manner from intracellular st
233  from a specific binding site can take place in a path-independent manner given reasonable values of
234 ifications can redistribute along the genome in a sequence-independent manner, giving rise to chromat
235  that induces acute Montipora white syndrome in a temperature-independent manner had similarly reduce
236 lude the ability to bind double-stranded DNA in a sequence-independent manner, homodimerize, and bind
237   Additionally, NPY and Y5R were upregulated in a BDNF-independent manner in NB cells under pro-apopt
238 kinase regulates initial platelet activation in a contact-independent manner in the absence of Eph-ep
239 ag 2(-/-) serum enhanced HAdV-5 transduction in a FX-independent manner in CHO-CAR and SKOV3-CAR cell
240 eprivation, which increased KLF15 expression in a GR-independent manner in vitro, enhanced glucocorti
241 dase inhibitor (SLPI) is regulated by the AR in a ligand-independent manner in CRPC cells and require
242  of pathogenesis-related genes was increased in a stimulus-independent manner in these plants.
243 However, CdiA also promotes auto-aggregation in a BamA-independent manner, indicating that the exopro
244  Pol II occupancy profiles to shift upstream in a FACT-independent manner indicative of a defect in p
245 ly, Nixin physically interacts with calnexin in a glycosylation-independent manner, induces calnexin
246     The histone variant H3.3 is incorporated in a replication-independent manner into different regio
247 ration of human first-trimester trophoblasts in a ROS-independent manner involving MAPK.
248                             IL-6, stimulated in a cAMP-independent manner, is an important mediator i
249                                 GRK5, acting in a kinase independent manner, is a facilitator of NFAT
250       The signature of genes regulated by MT in a tissue-independent manner may have prognostic value
251 NSCs increased expression of Ccl5 and Cxcl10 in a p53-independent manner, mediating increased infiltr
252 cyte precursors, suggesting that INX-14 acts in a channel-independent manner or INX-14 channels are d
253 egrins in TIE2lo ECs, subsequently inducing, in a TIE2-independent manner, phosphorylation of the int
254             Syk mediates bronchoconstriction in a NO-independent manner, presumably via rho kinase an
255        NPC4 hydrolyzes various phospholipids in a calcium-independent manner, producing DAG and a pho
256                     Protons regulate TMEM16A in a voltage-independent manner, regardless of channel s
257       The ASC-derived iPSCs can be generated in a feeder-independent manner, representing a unique mo
258 and nucleo-cytoplasmic concentration of Nrf2 in a Keap1 independent manner resulting in inefficient t
259 re-induced loss of ITGA4 expression on HSPCs in a SMAD-independent manner, resulting in improved homi
260 lts suggest that Parkin affects mtDNA levels in a mitophagy-independent manner.SIGNIFICANCE STATEMENT
261 sites within the Pro-Pol region were cleaved in a context-independent manner, suggesting for these si
262 , a signal modulator of stomata development, in a ligand-independent manner, suggesting that ERECTA,
263 n isogenic virus encoding mitochondrial PB2, in a MAVS-independent manner, suggesting a role for PB2
264 electively enhance abdominal SOP development in a Spitz-independent manner, suggesting additional gen
265            Activation of these unusual cells in a TCR-independent manner suggests that they are malad
266 me telomerase, some cells elongate telomeres in a telomerase-independent manner, termed alternative l
267 tically, P14ARF activated the TFPI2 promoter in a p53-independent manner that relied upon c-JUN, SP1,
268  alpha-helical conformation and binds 14-3-3 in a phosphorylation-independent manner that is differen
269                      Activation is initiated in a Trem2-independent manner that involves downregulati
270 able of activation of this signaling cascade in a ligand-independent manner, thereby promoting arteri
271 t upregulate the expression of PCH1 and PCHL in a phyB independent manner, thereby increasing the res
272  increases the degradation of other proteins in a ubiquitin-independent manner, this mechanism may un
273     However, some transcripts are translated in a cap-independent manner through poorly understood me
274 lidate predictions that shape-sensing occurs in a tension-independent manner through integrin beta3 s
275  binding FKBP12 increase hepcidin expression in a ligand-independent manner, through BMP-SMAD signali
276 t that CaMKIIbeta operates at the centrosome in a CaMKIIalpha-independent manner to drive dendrite re
277 also associates with autosomes of germ cells in a DCC-independent manner to enrich H4K20me1 and trigg
278 or in congenital heart disease pathogenesis, in a deacetylase-independent manner to regulate developm
279 nduced cell death, indicating that Ack1 acts in a kinase-independent manner to promote TRAIL-R1/2 acc
280 is sufficient to sustain intrinsic signaling in a LIF-independent manner to promote ES cell pluripote
281 suggest that multiple memory systems operate in a parallel, independent manner to encode emotional me
282            Moreover, Mps1 kinase contributes in a SAC-independent manner to the correction of erroneo
283 containing nucleosomes remain highly dynamic-in a modification-independent manner-to control neuronal
284 hereby CTLA-4 is constitutively internalized in a ligand-independent manner undergoing both recycling
285 o the contrary, cells were sensitized to CPT in a veliparib-independent manner upon transfection with
286 cally evaluating the accuracy of an assembly in a reference-independent manner using rigorous statist
287 tro, SEB could directly stimulate iNKT cells in a CD1d-independent manner via MHC-II/TCR interaction,
288                  NO also appears to function in a cGMP-independent manner, via S-nitrosation (SNO), a
289 -Myc, CYR61, and Pim-1, which are translated in a cap-independent manner, were shifted to heavier pol
290                     However, A3H hapII acted in a deaminase-independent manner when restricting HTLV-
291 at Salmonella can move on 0.3% agarose media in a flagella-independent manner when experiencing the P
292 groove allow Ago2 to interrogate target RNAs in a sequence-independent manner, whereas an adenosine b
293 pecificity, and forms two types of complexes in a metal-independent manner, which may explain the wid
294 F expression sensitizes cells to ferroptosis in a p53-independent manner while ARF depletion induces
295 ores and increases MET activity in GBM cells in a hypoxia-independent manner, while inducing a progra
296 at allow macroscopic objects to be described in a measurement-independent manner, while largely prese
297  (LMP1-CTAR1), activates both STAT3 and EGFR in a serum-independent manner with constitutive serine p
298 hotobleaching show that human FZD4 assembles-in a DVL-independent manner-with Galpha12/13 but not rep
299 lutely required for phosphorylation of STATs in a SMAD-independent manner within minutes of TGF-beta
300  to insert exogenous PCR-generated sequences in a homology-independent manner without loss of additio

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