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1 posed of two enantiomers with 68% and 44% ee in favor of (+)-(3S,4S)-M7 and (+)-(5S,6S)-M9, respectiv
2 tegration of prior information with evidence in favor of a choice reversal.
3 omputational modeling, to establish evidence in favor of a class of drift-diffusion models of rhythmi
4 ses and are, to date, the strongest evidence in favor of a cognitive role for melanopsin, which may c
5 ials both with and without a SAS would argue in favor of a cortically stored response.
6 traction attributable to periodontal reasons in favor of a dental implant should be carefully conside
7 ure of this blood extra copper burden is not in favor of a dietary origin but rather suggests a reall
8                      Our data strongly argue in favor of a direct competition between NusA and Rho fo
9 s are avoiding potatoes and sugary beverages in favor of a greater variety of carbohydrate foods, par
10                        Although the evidence in favor of a link between red and processed meat and co
11 eward processing and active reward dismissal in favor of a long-term goal.
12                      Altogether our data are in favor of a model by which Futsch locally stabilizes a
13 ed us to rule out several candidate theories in favor of a model that integrates across multiple para
14 l results have challenged this view, arguing in favor of a more integrated view of visual processing.
15 his process, epithelial traits are repressed in favor of a motile mesenchymal phenotype.
16 ty of a cerebellar contribution to attention in favor of a motor explanation, namely, eye movements.
17 inally, competing interests can lead to bias in favor of a particular intervention.
18                        However, the evidence in favor of a particular value of K cannot usually be co
19 ce between pathogenic and commensal bacteria in favor of a pathogen.
20 ave led us to revise our original hypothesis in favor of a pathway involving radical intermediates.
21     Leibovich et al. argue that the evidence in favor of a perceptual mechanism devoted to the extrac
22 ive fertilization success of competing sperm in favor of a preferred mate [1, 2].
23 resent study constitutes functional evidence in favor of a role for the HBs in memory processes, and
24 milarity with yscW from Yersinia spp. argued in favor of a role in machinery assembly.
25 that of a proton-shuttle pathway, is refuted in favor of a simple but computationally intractable aci
26 uthern Sierra or low-elevation Owens Valley, in favor of a simple isolation model with no migration b
27  versus 89.6% (HR, 1.45; 95% CI, 0.8 to 2.5) in favor of ABVD + INRT.
28 versus 87.1% (HR, 15.8; 95% CI, 3.8 to 66.1) in favor of ABVD + INRT; the U group, 92.1% versus 89.6%
29  of use of VR-SIM could prove to be features in favor of adoption as an alternative to destructive pa
30 ate that mineral formation can be diminished in favor of adsorption, regardless of reduction pathway.
31  in broad-spectrum antibiotic prescriptions, in favor of amoxicillin.
32 rites, thereby creating a relative imbalance in favor of amygdala inputs.
33                    Herein, we offer evidence in favor of an alternative reaction mechanism involving
34 inflammatory response in the diseased kidney in favor of an anti-inflammatory milieu with a reduction
35     Our results provide statistical evidence in favor of an association of polyomaviruses and their h
36 he balance between excitation and inhibition in favor of an excitatory cortical state.
37  expansion of reconstituted gene sets argues in favor of an expanded omnigenic model view on the gene
38 as locking the SD3-SD4 interface flexibility in favor of an extended conformer increased activity.
39 hubs shifting emphasis from subcortical hubs in favor of an increasingly prominent role for frontal h
40                                 The evidence in favor of an independent prognostic value also of some
41  both systems work in parallel, others argue in favor of an interaction between motivation and cognit
42 remains uncertain, with some studies finding in favor of an inverse association and some against.
43                         This argued strongly in favor of an isolated molecular event and against a co
44 s the recommendation that PBC not be delayed in favor of an NPBC in patients with partially platinum-
45 tumors (P = 0.142), a significant difference in favor of anatomical resection was observed in patient
46 eceased patients, and examine arguments both in favor of and against allowing relatives to "veto" the
47                         We discuss arguments in favor of and against contact precautions for ESBL-EC
48 ate T-cell apoptosis, which tips the balance in favor of antiapoptotic signals and endows these cells
49 ciated with the collapse of lipid metabolism in favor of antimicrobial responses.
50 shifted the balance of Bcl-2 family proteins in favor of apoptosis, and decreased migration and intra
51 inappropriate desires, emotions, and actions in favor of appropriate ones.
52 n post hoc analyses, significant differences in favor of asenapine over placebo were seen in time to
53               Financial and prosocial biases in favor of attractive adults have been documented in th
54 to be more consistent or stronger than those in favor of attractive men, and biases are more consiste
55 stent with evolutionary explanations, biases in favor of attractive women appear to be more consisten
56  for the manipulation of host cell signaling in favor of bacterial pathogens.
57 site at low ATP concentrations, which shifts in favor of "base-off" Co(II)Cbl in the presence of exce
58 pathways was computed to be 1.2 kcal mol(-1) in favor of BCB formation.
59 ft the Bcl-x 5'-splice site (5'SS) selection in favor of Bcl-x(S), we investigated the potential link
60 rder (MDD) largely ignore biological factors in favor of behavioral symptoms.
61 mixed, with some showing significant changes in favor of benralizumab and others not showing signific
62 esion revascularization continued to diverge in favor of BES-treated patients (5.8%) compared with BM
63 r modeling to repurpose nucleoside scaffolds in favor of binding at nonpurine receptors as novel 5HT2
64                          Although some argue in favor of bistability, others argue against it.
65 nd the major histocompatibility complex, and in favor of blond hair and blue eyes.
66  gradual elimination of fee-for-service care in favor of bundled payments will place additional risk
67         This study provides strong arguments in favor of cART initiation at the earliest possible tim
68 16 to -0.86; P = .003) and a Cohen d of 0.31 in favor of CBASP.
69 tistically significant but small differences in favor of CBT in several outcome measures, no differen
70 in CHI-D, but with G1/S molecules positioned in favor of cell cycle progression.
71                                    This bias in favor of charge-separated states has important conseq
72 commendations to provide stronger statements in favor of chemotherapy (with or without radiation ther
73     Abandonment of combined-modality therapy in favor of chemotherapy alone negatively affects patien
74 educed relapse rate (44% +/- 3 vs 35% +/- 3) in favor of clofarabine and an increased death probabili
75              T-cell proliferation was skewed in favor of CM and EM CD4Tcon and CD8 T cells, especiall
76 on gradients of host-cell-produced cytokines in favor of complement-derived anaphylatoxins, which the
77 group A patients (P<0.001), for a difference in favor of complete PVI of 17.1% (95% confidence interv
78 hondria, imeglimin redirects substrate flows in favor of complex II, as illustrated by increased resp
79 .042) between CAD patients and controls, all in favor of controls.
80 l population, skewing the NK cell repertoire in favor of cytotoxic responses at the expense of cytoki
81 willingness to forgo immediate small rewards in favor of delayed larger rewards.
82 ansplanted for alcoholic cirrhosis were less in favor of direct contact.
83       In fact, substitution rates are biased in favor of dominant sex determining chromosomes, which
84 s and shifted the ratio of viral dsRNA/ssRNA in favor of dsRNA.
85 involve the gradual accumulation of evidence in favor of each available choice.
86 erms of evidence integration: Noisy evidence in favor of each option accrues over time, until the evi
87 rapy with conventional antiepileptic therapy in favor of early limitation of care or novel neuroprote
88 -3, together with Ag, drives differentiation in favor of effector T cells via the activation of mTOR
89 imized to reduce individual metabolic burden in favor of enhanced crossfeeding to support synergistic
90 supplant the influence of macrophage origins in favor of environmental demands.
91  was not significantly different but trended in favor of everolimus (16.5 v 22.8 months; hazard ratio
92   In this Personal Viewpoint essay, we argue in favor of expanding one such pilot project-the Compreh
93 isengaging from the newly ineffective action in favor of exploring an alternative action.
94 D44 pre-mRNA to inhibit spliceosome assembly in favor of expressing the mesenchymal isoform CD44s ove
95 ansmission and a suppression of DMN activity in favor of externally-directed attentional processes.
96          This suggests a shift in processing in favor of FF information at the expense of intracortic
97 e was a statistically significant difference in favor of FLACS over MCS for effective phacoemulsifica
98      Rigid annuloplasty rings should be used in favor of flexible bands or DeVega-style repairs.
99                                     We argue in favor of four ideas.
100 II(lo) DCs, and skewed the Treg-Th17 balance in favor of Foxp3(+) Tregs while decreasing Th17 cells.
101 expression in healthy skin is down-regulated in favor of FSTL1 upon wounding, which enhances keratino
102 mparable behavior in prostate cancer models, in favor of future theranostic use in GRPR-positive canc
103  There was a trend toward long-term survival in favor of GemErlo (estimated survival after 1, 2, and
104 ys, we predicted a cumulative sex difference in favor of girls that occurred at approximately 6 mo of
105 ) in the DHS data between 6 and 17 mo of age in favor of girls.
106 nzyme that suppresses mitochondrial activity in favor of glycolysis.
107 other and regulate conformational equilibria in favor of headpiece opening.
108 havior and to forgo sugary snacks and drinks in favor of healthier options a day later in an unrelate
109 her against partially recessive mutations or in favor of heterozygotes, may result in an apparent sel
110           There were significant differences in favor of HFOV in several other measures of respirator
111 tine dose-dense chemotherapy in lymphoma and in favor of high-dose-intensity chemotherapy in urotheli
112           There was a significant difference in favor of high-flow oxygen in 90-day mortality.
113 ate that auditory cortical inputs are biased in favor of IC synaptic domains that are populated by SS
114 dance, and overall severity of dental phobia in favor of immediate treatment at the follow-up assessm
115 ne checkpoint inhibitors may tip the balance in favor of immune surveillance in these cancers.
116 periodontal disease is decreasing (P <0.001) in favor of implant-related research.
117 tability of sensory inputs can be sacrificed in favor of improved discriminability and that sensory a
118 nce between mitochondrial fusion and fission in favor of increased fission, reducing the metabolic ca
119 ol clearance, altered hepatic lipid profiles in favor of increased levels of polyunsaturated fatty ac
120 ce in BCVA gains at month 12 of +2.6 letters in favor of infrequent treatment).
121 ded host protein provides compelling support in favor of inteins acting as pause buttons to arrest pr
122  the context-based declarative memory system in favor of its overrepresentation in a cue-based sensor
123 al of beta-elimination substrate specificity in favor of l-serine over the normally preferred l-serin
124 e large labeled vesicles decreased in number in favor of labeled synaptic vesicles, and after 30 s, l
125 ol (i.e., forgoing smaller immediate rewards in favor of larger delayed rewards) without exerting add
126 revascularization rates (P=0.007) were found in favor of larger vessel size and oversized stents.
127 up of patients who did not complete therapy, in favor of later treatment (P < .001).
128  permanent stoma rates and anastomotic leaks in favor of LC but with an increased perineal wound brea
129 in the N-terminal region of Abeta aggregates in favor of less compact conformations.
130 is technology should focus on reducing these in favor of less impactful alternatives.
131 as 1.79 (95% confidence interval, 1.20-2.67) in favor of licensed drugs.
132  were shared by all affected relatives (odds in favor of linkage = 4,096:1).
133         Our results therefore strongly argue in favor of local immune remodeling at the onset of part
134 lify the tendency to forgo immediate rewards in favor of longer-term goals.
135 the drive to eat, forgoing immediate rewards in favor of longer-term goals.
136 pposes the expansion of high-avidity T cells in favor of lower-affinity populations.
137 ed and statistically significant gender bias in favor of males (p = 0.0016), but none of the clinical
138 tal studies provide more compelling evidence in favor of mating motives and suggest the direction of
139                            There was skewing in favor of memory T cells and intense autoantibody prod
140 suboptimal hiring choices that remain biased in favor of men.
141 rgo and thereby adjusts the energy landscape in favor of MHC I complexes with immunodominant epitopes
142 nal CDR3 binding with the associated peptide in favor of MHCII alpha-chain binding.
143       Phosphorylation drives the equilibrium in favor of monomeric forms, and this effect can be reve
144 t to improve long-term outcomes may diminish in favor of more repetitive or exploitatory choices.
145 mily of molecules traditionally deemphasized in favor of myelin proteins in studies of CNS autoimmuni
146 cant difference in the DRI score at 3 months in favor of nail fixation (mean score, 44.2 in the nail
147 nt difference in mean OMAS at 3 and 6 months in favor of nail fixation.
148                                    Arguments in favor of NBS include benefits of early intervention a
149 brain barrier in a discriminating way biased in favor of non-pathogenic CD8(+) T cells relative to ot
150 ranscriptase inhibitors in the cART regimen, in favor of nucleoside reverse transcriptase inhibitors
151                        Treatment differences in favor of ocriplasmin were generally observed across e
152 unger females may prompt males to avoid them in favor of older but more fecund females.
153  a significant and moderate to strong effect in favor of omega-3.
154 option accrues over time, until the evidence in favor of one option is significantly greater than the
155 ligands that can "bias" downstream signaling in favor of one or the other process.
156 d provided the rationale for recommendations in favor of or against treatment interventions for idiop
157  number of Americans choose to curtail sleep in favor of other social, leisure, or work-related activ
158  activator by replacing binding of CtBP/BRG1 in favor of p300.
159                     This retreat from theory in favor of particularism is based on the faulty beliefs
160  Next, we describe and discuss the arguments in favor of permitting donation intentions to be overrul
161 respectively, were statistically significant in favor of PET/CT.
162                             Publication bias in favor of positive findings influences the distributio
163    The following differences were identified in favor of PRA vs LTLA: shorter duration of surgery (50
164 o exclude DCM compounds from screening decks in favor of previously untested or less tested compounds
165 at induces cell death by tipping the balance in favor of proapoptotic gene expression.
166 ], 3.1 to 5.5 ml/min per 1.73 m(2); P<0.001) in favor of PTF.
167 tion of AED location was consistently skewed in favor of public locations.
168     This argues against recycling models and in favor of pulling models.
169 nificance were seen in the mean healing time in favor of purse-string suture (P = .10) and scar relie
170  interneuron networks shifted their activity in favor of pyramidal neuron hyperactivity: somatostatin
171            Once there, it exchanges partners in favor of Ran.
172 ere was significant difference in BCVA gains in favor of ranibizumab.
173  types that normally bias their connectivity in favor of red cones fail to precisely recapture this s
174 ine data are essential to determining policy in favor of reducing poverty.
175 their sensitivity to global changes in light in favor of responses to spatial patterns.
176 or OPTX have led some groups to abandon FPTX in favor of routine 4-gland exploration.
177 st and the ACOG committee opinion recommends in favor of routine annual pelvic examination.
178 und complications (38.3% vs 50.0%, P = 0.26) in favor of SC.
179 s, such as CO2 per capita, should be avoided in favor of sectorial benchmarks, such as industry, tran
180  the ratio of Cdk1/PP1alpha activity changes in favor of Ser68 dephosphorylation, thus making CENP-A
181 IL-2 can augment the gammadeltaT-17 response in favor of short-lived effectors with limited plasticit
182 ain coding sequence and is tightly regulated in favor of skipping in neurons; however, its biological
183     This study provides encouraging evidence in favor of SMAPs as potential anticancer drugs.
184 ll SLN detection OR of 2.5 (95% CI, 1.2-5.3) in favor of SPECT/CT.
185 power to detect a hazard ratio (HR) of 0.315 in favor of SRB, using a one-sided type I error rate of
186  achieved a statistically significant result in favor of standard therapy or a null result with no st
187          There was a significant improvement in favor of stem cell treatment in performance status an
188 tegies that target TAMs indiscriminately and in favor of strategies that specifically target immunosu
189 y rates 4-6 fold and shifting the microbiome in favor of stress-associated taxa.
190 revious revascularization (adjusted HR: 0.82 in favor of such treatment; 95% CI: 0.75 to 0.91).
191               We provide two major arguments in favor of Sul1 and Sul2 acting as transceptors for sig
192 uction of NAbs, but there are good arguments in favor of suppressing such "off-target" immune respons
193     This defect shuts off miR-198 expression in favor of sustained FSTL1 translation, driving metasta
194 asing of competitive local neuronal dynamics in favor of task-relevant stimuli [6], this "inhibitory
195 nges in the percentage of the predicted FEV1 in favor of tezacaftor-ivacaftor over placebo were 4.0 p
196 ific regulatory T cells; or immune deviation in favor of TH1 responses.
197 ations where Th1 responses should be limited in favor of Th2 responses.
198 ulation, hence rejecting "simple regulation" in favor of the "coordinate regulation" model.
199        These experimental results bring data in favor of the (99m)Tc-NTP 15-5 radiotracer for assessi
200          The reaction is diastereoselective, in favor of the 1S epimer, when large groups are attache
201  results, and increase of specific IgG4 were in favor of the active treatment.
202 terol shifts the conformational distribution in favor of the active-like conformation, whereas bindin
203  in the high-risk subgroup there was a trend in favor of the adjuvant arm.
204 fined by expression of fmyhc1.2 and fmyhc1.3 in favor of the anteriormost myosin isoform, fmyhc1.2.
205 Our data have provided experimental evidence in favor of the application of positive stress or of ben
206 ing, or allosteric, hypothesis was abandoned in favor of the associative hypothesis, which posited th
207 eshold, which represented the total evidence in favor of the chosen target.
208 equilibrium is shifted strongly (10:1 ratio) in favor of the closed E* form and unfolds over a faster
209 few long ones thus providing strong evidence in favor of the compositional domain model and seem to i
210 rates of any breastfeeding ranged from 14.1% in favor of the control group to 18.4% in favor of the i
211 t spread into the crystallographic community in favor of the cross-validation method known as [Formul
212 ificant effect on hematogenous dissemination in favor of the CRT group (35% v 29%; P = .025).
213 tion temperatures also serves as an argument in favor of the cryoprotective role of the cytoskeleton.
214            Rather than staking out positions in favor of the ctenophores-sister or the sponges-sister
215 with an ensemble weighted almost exclusively in favor of the desired conformation.
216 n C-1 of the acceptor displaced the reaction in favor of the desired galactofuranosyl containing disa
217  return with, on average, a directional bias in favor of the dominant segregating sex chromosome.
218 ed for postprocedural extracorporeal support in favor of the DS group (odds ratio, 0.22; 95% confiden
219   Improvement in favorable outcome at day 90 in favor of the endovascular group did not reach signifi
220  novel near-infrared-responsive nanomedicine in favor of the enhancement of therapy efficacy and bios
221              Altogether, these results argue in favor of the existence of a rodent-like MZB cell line
222 duce the pool of soluble toxic Abeta species in favor of the formation of larger insoluble nontoxic a
223  between the immune system and cancer or HIV in favor of the former, allowing elimination of diseased
224 stematically bias successive lineage choices in favor of the generation of a specific cell type.
225 yond examination of specific candidate genes in favor of the genome-wide association study (GWAS) str
226  selectivity shift of approximately 100-fold in favor of the herpetic DNA polymerases when compared t
227 tics tools, we have obtained strong evidence in favor of the HN stalk-mediated activation of paramyxo
228  may develop therapeutics to tip the balance in favor of the host.
229  In total, our study provides strong support in favor of the hypothesis that protein aggregation is n
230 kpoint inhibitor therapy to tilt the balance in favor of the immune system.
231   Recent experiments provide sound arguments in favor of the in vivo expression of the AntiSense Prot
232  primary outcome scores shifted consistently in favor of the intensive strategy, with a common OR for
233 independence (modified Rankin score, 0 to 2) in favor of the intervention (32.6% vs. 19.1%).
234 ing complications were significantly reduced in favor of the intervention (OR = 0.401; CI, 0.302-0.53
235                               Both acORs are in favor of the intervention (P for interaction = 0.07).
236 vitamin D, and antihypertensive medications, in favor of the intervention group.
237 14.1% in favor of the control group to 18.4% in favor of the intervention group.
238 was 2.32 (95% confidence interval, 1.17-4.15 in favor of the intervention).
239 overall acOR was 1.67 (95% CI, 1.21 to 2.30) in favor of the intervention.
240                                    Arguments in favor of the latter are unilateral manifestation, as
241 hifted the MHC-II(lo)/MHC-II(hi) TAM balance in favor of the latter as observed by the preferential d
242 age 2: 2-formyl-6-methylpyridine was ejected in favor of the less sterically hindered 2-formylpyridin
243 as people give up use of a minority language in favor of the majority language in a process called la
244 -Meier curves showed significant differences in favor of the mesh group (long-rank = 4.21, P = 0.04).
245 eductive elimination is predicted to be more in favor of the methyl group than the methylene of the p
246  good yield and in high diastereoselectivity in favor of the more stable isomer.
247 nt satisfaction (5.4 v 2.0 points; P = .001) in favor of the MP compared with the PL group, respectiv
248  present, the transport of TOrCs is hampered in favor of the NaCl transport, which shows a preferenti
249 pecific processing of the artificial BenziTP in favor of the natural dNTPs.
250  achieved a statistically significant result in favor of the new experimental treatment for the proto
251  response of visual cortex binocular neurons in favor of the nondeprived eye, a process named ocular
252 inhibit swarming by skewing stator selection in favor of the nonfunctional, "bad" stators.
253  task workload, and questionnaire assessment in favor of the novel viewer, as compared to all 3 modal
254 oints, although there were small differences in favor of the NRCA cohort on several KCCQ subscales at
255 n of a Bayes factor provided strong evidence in favor of the null hypothesis.
256 difference during the first year (P = .0102) in favor of the observation arm.
257 utilization of the two functional ET chains, in favor of the one that does not bear the charged speci
258 s below critical maxima, tipping the balance in favor of the parasite.
259       The 17 cases that resulted in verdicts in favor of the pediatric plaintiff had a mean jury awar
260 tam antibiotics as potential inhibitors, and in favor of the peptidoglycan substrate.
261 dness were more likely to result in verdicts in favor of the plaintiff (difference, 60.5%; 95% CI, -1
262 tric patients was more likely to be resolved in favor of the plaintiff and was associated with higher
263                  Of these 35 cases, verdicts in favor of the plaintiff were issued in 17 pediatric ca
264 ophthalmitis were more likely to be resolved in favor of the plaintiff.
265 hat exogenously administered CgA was cleaved in favor of the proangiogenic form and was associated wi
266 ants in Brazil and Haiti and report evidence in favor of the putative role of human mobility in facil
267 be advisable to limit global recommendations in favor of the regionally focused ones.
268                        A bias was also found in favor of the right hemisphere consistent with functio
269 ant difference between them but with a trend in favor of the rituximab group at 12 months.
270 t difference between groups but with a trend in favor of the rituximab group.
271                     We found strong evidence in favor of the second hypothesis, showing that attentio
272              Overall, we identified evidence in favor of the standard model with fixed decision bound
273                      Here, we bring evidence in favor of the supramodality hypothesis by showing that
274 nd PD were found to be significant (P <0.05) in favor of the test group at all time points.
275 g potential energy landscape, and skewing it in favor of the unloaded side, and in some situations ad
276 elieve that these results bring new insights in favor of the use of the non invasive QCM-D technique
277                            These results are in favor of the use of UAEPC as potential additive in fo
278             The results provide new evidence in favor of the view that the hippocampus is essential f
279 ant, and the authors offer several arguments in favor of their strategy.
280 esses in the incongruent condition and speak in favor of theories that assume a longer duration of sp
281 l-5D quotient was of borderline significance in favor of therapy (-0.03; 95% CI, -0.07 to -0.002; P =
282 7 to 0.03; P = .04) showed small differences in favor of therapy.
283                       Nevertheless, evidence in favor of these models is mixed, with support coming f
284 ement learning task, we show strong evidence in favor of this hypothesis.
285 back signals that bias early visual activity in favor of top-down goals.
286            Abhay Sharma brings two arguments in favor of transgenerational epigenetic inheritance (TG
287 hormones can shift the immunological balance in favor of Tregs via differential engagement of the GR
288 nisms may exist to modulate MEK/ERK activity in favor of tumor cell proliferation.
289 uce ROS production, and thus tip the balance in favor of tumor cell survival and treatment-refractory
290 o and transformed the tumor microenvironment in favor of tumor eradication.
291  the ECT course (mean difference=1.08 points in favor of unilateral ECT [95% CI=-1.67 to 3.84]).
292                                Here we argue in favor of using an objective approach to phylogeograph
293 rences between the two prosthetic techniques in favor of using DAs.
294 quilibrium from dimer formation dramatically in favor of viral capsid assembly.
295 by altering the host gene expression program in favor of viral persistence.
296 d skewed the embryonic genotype distribution in favor of wild-type alleles.
297 lyamine metabolism that biases fertilization in favor of wild-type gametes.
298 mental management, they are often overlooked in favor of win-wins.
299  changes in CO2 and fire shifted the balance in favor of woody plants.
300 lity of K2 to bind the (pro)catalytic domain in favor of zymogen, thereby enforcing zymogen-like char

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