1 (T2D) is a complex and polygenic disease yet
in need of a complete picture of its development mechani
2 New faculty are
in need of a formal program endorsed by their administra
3 of homophily is that the people who are most
in need of a health innovation may be among the least li
4 ion coverage--the proportion of a population
in need of a health intervention that actually receives
5 over 4 million volunteer donors for patients
in need of a hematopoietic stem cell transplant.
6 The majority of patients
in need of a hematopoietic-cell transplant do not have a
7 D allocation policy, patients that are least
in need of a liver transplant now receive the highest-ri
8 Psychiatry is
in need of a major overhaul.
9 major update is required; 6 were found to be
in need of a minor update; 3 were judged as still valid;
10 9-N cells should prove useful to researchers
in need of a model cell culture system in which to study
11 The field is greatly
in need of a more unified approach to its definition and
12 n of patients with severe TBI and severe TBI
in need of a neurosurgical intervention were similar in
13 d not help identify patients with severe TBI
in need of a neurosurgical intervention.
14 77 patients (1%) with a GCS score of 15 were
in need of a neurosurgical operation, and fewer than 51
15 pharmacology, has left integrin therapeutics
in need of a new strategy.
16 Seventeen patients (20 total sites),
in need of a non-molar extraction and delayed implant pl
17 al dominant polycystic kidney disease (APKD)
in need of a renal transplant.
18 nical decisions; policy makers are similarly
in need of a rigorous patient-centered, comparative effe
19 a-cells after expansion is still a challenge
in need of a solution.
20 lion volunteer unrelated donors for patients
in need of a stem cell transplant.
21 they were preliminary matches with patients
in need of a transplant.(1) The study found that people
22 y before their recipient is matched, or even
in need of,
a kidney transplant, and deceased donor init
23 ) > or =5 mm and bleeding upon probing (BOP)
in need of access flap surgery (AFS).
24 al circuitry that remain opaque and that are
in need of additional experimentation to enrich our unde
25 viduals with occult opportunistic infections
in need of additional screening.
26 al cancer at high risk of recurrence who are
in need of adjuvant treatment.
27 However, the most important areas
in need of advancement, outcome studies and new therapeu
28 hich patients develop severe disease and are
in need of aggressive treatment.
29 h has collected HLA typing from CLL patients
in need of allogeneic hematopoietic stem cell transplant
30 The majority of patients are not
in need of an acute intervention beyond decongestion, an
31 at high risk of biochemical failure, who are
in need of an effective neoadjuvant therapy.
32 Many infectious diseases are still
in need of an effective vaccine including HIV, malaria,
33 hese 2 techniques in female patients who are
in need of an elective cholecystectomy.
34 The field is badly
in need of an explicitly multivariate approach to autoco
35 infections, and better targeting of children
in need of antibiotic prescription.
36 children with severe infections and children
in need of antibiotic treatment.
37 in subjects with criminal histories who are
in need of antipsychotic medication.
38 iliar that they rarely strike us as standing
in need of any explanation in the first place.
39 % (92.2-92.9) of individuals would have been
in need of ART with immediate initiation, initiation at
40 ound a substantial population to be viremic,
in need of ART, and at risk for transmission.
41 survival time, the proportion of individuals
in need of ART, and the proportion of individuals with H
42 However, the quantity of chemicals
in need of assessment and the challenges of species extr
43 d (ca 4000 species) of all freshwater fishes
in need of assessment by 2020.
44 se at the highest risk for asthma burden and
in need of assistance.
45 ailable to help clinicians identify patients
in need of assistance.
46 Questions currently
in need of attention include how to identify and treat p
47 Among adolescents
in need of behavioral health services, co-occurring diso
48 The lipidomics community is
in need of benchmark reference values to assess the vali
49 es are devastating conditions that are still
in need of better understanding, and both oligodendrocyt
50 , and discussion of the report with patients
in need of cardiac surgery.
51 sis has been recognised as an abnormal state
in need of care throughout history and by diverse cultur
52 also experienced by individuals who are not
in need of care.
53 e to expand prison populations with patients
in need of care.
54 odulated by precursor binding is complex and
in need of careful dissection.
55 nguishing non-cancerous specimens from those
in need of careful examination and could help save time
56 nical practices in oxygen administration are
in need of change based on the increasing understanding
57 tributions and resources available to people
in need of chronic illness management and support.
58 s are promising, particularly for candidates
in need of CLDLITx.
59 , therefore, target NEC infants who are most
in need of close monitoring and those who may benefit fr
60 be important for identification of patients
in need of closer cardiovascular monitoring.
61 r clinical diagnosis as it may flag patients
in need of closer monitoring.
62 are needs constitute a vulnerable population
in need of comprehensive and accessible care.
63 t could be used to routinely screen patients
in need of comprehensive follow-up.
64 retical calculations so far, which have been
in need of confirmation from real catalysis.
65 Waterlogged archaeological wood is often
in need of consolidation prior to drying to prevent shri
66 al or a pool of deleterious alleles that are
in need of constant suppression.
67 rognostic indicators found in this study are
in need of continued inpatient care to avoid immediate r
68 When
in need of continued sedation, study patients received a
69 work structure, whose relative importance is
in need of continuing study.
70 Early identification of nontrauma patients
in need of critical care services in the emergency setti
71 ties between chronic hepatitis and cirrhosis
in need of determination to completely specify their mod
72 We first quantified the population
in need of diabetes diagnosis and care by estimating the
73 Those
in need of dietary change at baseline (n = 210) were exa
74 p physicians identify nursing home residents
in need of different therapeutic approaches for LRI.
75 ative assessment might help screen for those
in need of earlier intervention.
76 y to undergo spontaneous clearance and those
in need of early antiviral therapy.
77 and mortality make cancer a health challenge
in need of effective and better tolerated therapeutic ap
78 oorly understood at the genetic level and is
in need of effective therapeutic approaches.
79 re represents an enormous clinical challenge
in need of effective therapeutic approaches.
80 vanced form of cerebral small vessel disease
in need of efficacious therapeutic strategies.
81 produced in biology research, scientists are
in need of efficient data analysis methods.
82 d of identifying DRI nutrients that are most
in need of either a new or an updated systematic review.
83 lity, and identify children < 5 years of age
in need of emergency chelation therapy for lead poisonin
84 Most patients
in need of emergent abdominal operations should not unde
85 already have evidence for hepatitis C or are
in need of emergent transplantation.
86 Decision makers worldwide are
in need of empirical data to inform and implement emerge
87 environment which are largely unexamined and
in need of empirical data.
88 opic of breaking bad news, the literature is
in need of empirical work.
89 suscitate orders, advance directives, or are
in need of end-of-life care.
90 t a bare-minimum estimate of rectal bleeding
in need of evaluation and treatment.
91 24 604 individuals with rectal bleeding are
in need of evaluation in Sierra Leone.
92 this review, we put forward the main issues
in need of evidence and propose a different approach to
93 stion whether depletion is a real phenomenon
in need of explanation.
94 el1p targets telomerase to the DNA ends most
in need of extension.
95 Twenty-four consecutive subjects
in need of extraction of maxillary premolars were recrui
96 Given the extent of western forests
in need of fire restoration, efficiently allocating trea
97 independent cohorts of symptomatic patients
in need of first-line immunochemotherapy (151 patients f
98 to identify middle and high school students
in need of formal evaluation for posttraumatic response
99 l subgroups, however fewer than 50% of women
in need of FP use modern contraception in Senegal.
100 mong the top 10 proteins of unknown function
in need of functional characterization, while YeaZ and Y
101 ication of many novel mitochondrial proteins
in need of further characterization.
102 Career development issues are broad and
in need of further development by the Society of Critica
103 for analyzing network-level observations is
in need of further development.
104 ts to nucleotide metabolism as the area most
in need of further experimental study.
105 eria leading to predictable regeneration are
in need of further exploration.
106 fidence intervals for accuracy estimates are
in need of further improvement.
107 to which age modifies these associations is
in need of further investigation in large, community-bas
108 Areas
in need of further investigation include the mechanism(s
109 natural host-microorganism communication is
in need of further investigation.
110 tein domains have function and therefore are
in need of further investigation.
111 and therapies and highlight important areas
in need of further investigation.
112 e been accumulating in RNA databases and are
in need of further molecular characterization.
113 reliable method to identify cancer survivors
in need of further neurocognitive follow-up.
114 nding, as embodied in this working model, is
in need of further refinement, and the results presented
115 expected outcomes, while highlighting areas
in need of further research and technological advancemen
116 Finally, we will outline areas
in need of further research because understanding the re
117 using an evidence-based approach, and areas
in need of further research were identified.
118 e in patients with PEW, and highlights areas
in need of further research.
119 ghted as an area of clinical concern and one
in need of further research.
120 Areas
in need of further study were identified.
121 ological mechanisms driving this outcome are
in need of further study, trematode infections appear to
122 ion of category, rather than a criterion set
in need of further study, will provide greater legitimac
123 ltifunctional nonparenchymal cell population
in need of further study.
124 oReview will help to pinpoint the areas most
in need of further study.
125 th gaps in knowledge are identified as areas
in need of further study.
126 ns when possible, and suggest areas that are
in need of further study.
127 ith hoarding symptoms represent a population
in need of further treatment research.
128 film formation must be approached as a model
in need of further validation, rather than utilized as a
129 s, their treatment, and areas of uncertainty
in need of future investigation.
130 ific goals of identifying areas particularly
in need of future research and of articulating an initia
131 nterest are then examined and critical areas
in need of future research are identified.
132 e treatment options; and (3) highlight areas
in need of future research.
133 a BL from an alternative class for patients
in need of gram-negative antibiotic coverage.
134 impaired adolescents is a salient challenge
in need of greater attention and further research.
135 ts with chronic illness is a serious problem
in need of greater recognition and intervention and furt
136 sthospital care options are ill-prepared and
in need of guidance.
137 dly growing age group globally, and are most
in need of health care and assistance.
138 d health outcomes in remote populations most
in need of health services.
139 s a rationale for service provision to those
in need of help who could not previously access it and t
140 , of those adolescents who were likely to be
in need of help, only about 9% received treatment.
141 native means of vascular access for patients
in need of hemodialysis who cannot undergo dialysis thro
142 e than 300 000 people in Nepal are currently
in need of herniorrhaphy.
143 assessment of dietary acrylamide exposure is
in need of high quality methods for evaluating dietary e
144 These patients are
in need of high surveillance.
145 ments will be of great value to applications
in need of high-throughput yet sensitive flow cytometry
146 for patients who have serious mental illness
in need of hospital-level care and who are willing to ac
147 All patients with acute ischemic stroke are
in need of hyperacute secondary prevention because the r
148 Answering pages from nurses about patients
in need of immediate attention is one of the most diffic
149 Answering pages from nurses about patients
in need of immediate attention is one of the most diffic
150 hostile attributions may help identify those
in need of immediate practitioner input and/or referral
151 (HFpEF) is a heterogeneous clinical syndrome
in need of improved phenotypic classification.
152 riod), is a significant public health burden
in need of improved treatment.
153 in guiding investigators towards areas most
in need of improved treatment.
154 ld, the body of work also exposes some areas
in need of improvement in study design, selection of out
155 n and laboratory practice standards are most
in need of improvement to ensure quality in clinical mol
156 End-of life care is
in need of improvement, yet little is known about the ef
157 mathematical formulations are appropriate or
in need of improvement.
158 tion to skill retention, and other areas are
in need of improvement.
159 new or stricter protections and 514 species
in need of improvements to fisheries management.
160 be useful in identifying health-care systems
in need of improving end-of-life services.
161 rapidly proliferating cancer cells that are
in need of increased protein synthesis.
162 ort, enables early identification of infants
in need of increased surveillance for TR-ROP.
163 rk to date has further highlighted the areas
in need of innovation as we continue to strive to improv
164 set of patients with carotid atherosclerosis
in need of intensified medical therapy or carotid artery
165 the neutropenic and nonneutropenic patients
in need of intensive care unit care, mortality, or attri
166 tant system for identifying complex patients
in need of intensive care.
167 entifying those with Barrett's esophagus and
in need of intensive surveillance, to an increasing numb
168 It remains a neglected tropical disease
in need of international recognition.
169 n health and identify population groups most
in need of intervention programs.
170 epends on early identification of those most
in need of intervention.
171 that can serve as foci for identifying youth
in need of intervention.
172 can use these findings to identify children
in need of intervention.
173 provide a framework for identifying families
in need of intervention.
174 mm Hg) who were admitted to the hospital and
in need of intravenous treatment for acute HF and centra
175 health behavior, especially among those most
in need of it.
176 erformed in 29 consecutive diabetic patients
in need of limb salvage.
177 eviate the organ shortage for small children
in need of liver transplantation.
178 technologies and training, and many patients
in need of local therapy, SBRT has found a place in the
179 d to preserve function in pediatric patients
in need of long-term pacing.
180 bstruction (11.7%), and anastomotic stenosis
in need of mechanical dilatation (10.7%).
181 Furthermore, nearly 60% of youth
in need of mental health services do not receive the car
182 an elevated risk for suicide may tend to be
in need of mental health services that can help them to
183 Among the children defined as
in need of mental health services, defined by an estimat
184 hile we recognize RECIST is far from perfect-
in need of modification as a measure of efficacy for som
185 d for early stratification of acute patients
in need of more aggressive treatment.
186 ent that species recognition in the group is
in need of more attention, and that many basic assumptio
187 d standardization of therapeutic approach is
in need of more careful study.
188 The world is
in need of more effective approaches to controlling tube
189 arcoma has a high mortality rate and remains
in need of more effective therapeutic approaches.
190 is a common soft-tissue sarcoma of childhood
in need of more effective therapeutic options.
191 fection constitutes a serious health problem
in need of more effective therapies.
192 ion constitutes a significant health problem
in need of more effective therapies.
193 may constitute an additional high-risk group
in need of more frequent skin cancer screening.
194 till an infant field, and we highlight areas
in need of more research, both theoretical and empirical
195 This review emphasizes areas
in need of more study, particularly phylogeny, phylogeog
196 till in an early stage of sophistication and
in need of more theoretical understanding.
197 the preferred strategy in patients with T1D
in need of multivessel revascularization.
198 nefit in patients with type 1 diabetes (T1D)
in need of multivessel revascularization.
199 was found between the proportion of patients
in need of neurosurgery with GCS scores of 3 to 8 and th
200 nts with severe traumatic brain injury (TBI)
in need of neurosurgical intervention is complicated in
201 nd Measures: Proportion of patients with TBI
in need of neurosurgical intervention per GCS score or S
202 iagnostic screening of intracranial injuries
in need of neurosurgical intervention, but may also prov
203 tion would identify patients with severe TBI
in need of neurosurgical intervention.
204 espect to their ability to identify patients
in need of neurosurgical interventions, no difference wa
205 ependence is a major public health challenge
in need of new treatments.
206 ocytic leukemia (CLL) is a B-cell malignancy
in need of new, effective, and safe therapies.
207 y difficult-to-treat cancer and patients are
in need of novel therapies.
208 me and young-adult households in the LMD are
in need of nutrition interventions with an emphasis on i
209 Eighteen patients
in need of oral prosthetic rehabilitation that included
210 at involve data sharing to identify patients
in need of palliative care, identification of better car
211 requiring expert perceptual skills or those
in need of perceptual rehabilitation (such as individual
212 ,100-70,500]) will remain the countries most
in need of policies for the prevention and management of
213 ypes can help identify high-risk individuals
in need of preventive interventions and can help inform
214 dent CKD and may aid in identifying subjects
in need of primary preventive regimens.
215 Women with recurrent breast cancer are
in need of programs to assist them with the severe effec
216 oportion of these lesions remains active and
in need of proper management.
217 oteomics measurements discover a host factor
in need of protection to improve resource redistribution
218 ith proliferative diabetic retinopathy (PDR)
in need of PRP were randomly assigned to 1 of 4 groups:
219 ory of self-harm or depression, which may be
in need of psychiatric support after GBP.
220 iders to identify childhood cancer survivors
in need of psychosocial services and provide them with a
221 ion of what is known about those individuals
in need of psychotherapy and how they access services.
222 ventilator protocol which targeted variables
in need of quality improvement, as identified by prior w
223 archers to reshape science-to identify areas
in need of reexamination, reweight former certainties, a
224 at can enter the circulation to reach organs
in need of regeneration.
225 anxiety disorder (GAD) is a chronic disorder
in need of reliable data to guide long-term treatment.
226 derly patients are the fastest-growing group
in need of renal transplantation.
227 ssed to ICDAS >/= 5 associated with sealants
in need of repair and none to halfway or more through th
228 udy (isolated orbital fracture thought to be
in need of repair, with diplopia within 30 degrees of pr
229 However, many of these findings are
in need of replication, and few have taken into account
230 While tentative and
in need of replication, these results, consistent with t
231 While
in need of replication, these results, validated by pred
232 Clinical potentials
in need of research are shifting from normotensive to hy
233 y areas of mast cell activation syndrome are
in need of research.
234 te diverticulitis and identifies other areas
in need of research.
235 compared with sham treatment in 807 infants
in need of respiratory support 24 hours after birth.
236 All patients
in need of revascularization were identified with corona
237 n 1997 that this nutrient is likely the most
in need of revised requirements.
238 ntly accepted picture of proton diffusion is
in need of revision.
239 twork as the major load-bearing structure is
in need of revision.
240 The AJCC staging system for RPS is
in need of revision.
241 sensitivity to climate may be misleading and
in need of revision.
242 eplacement of all indigenous populations, is
in need of revision.
243 /Ph-promoted radical conjugate additions, is
in need of revision.
244 by chemical correlation with 1 and 2 are not
in need of revision.
245 view of the nitrogen regulatory circuit was
in need of revision; additional components clearly exist
246 remains unproven, and as such, a hypothesis
in need of rigorous testing.
247 nfected and HIV/HCV co-infected patients are
in need of safe, effective, all-oral HCV regimens.
248 However, few mothers (15%)
in need of services received mental health care, and the
249 he wealthier households, who nonetheless are
in need of similar interventions.
250 A total of 25 patients
in need of sinus augmentation were recruited for the stu
251 lish-acculturated Hispanics are particularly
in need of skin cancer prevention interventions.
252 dual differences in how primates behave when
in need of social support.
253 atients with end stage organ failure who are
in need of solid organ transplantation has led to a heig
254 the previously predicted binding motifs are
in need of some revision.
255 Former child soldiers are considered
in need of special mental health interventions.
256 tation and clearly defines a high-risk group
in need of specific intervention.
257 uidelines differ in how they identify adults
in need of statin therapy; furthermore, it is unclear ho
258 predicted CVD risk category and, therefore,
in need of statin treatment under Adult Treatment Panel
259 Examples of areas
in need of study are highlighted, and I end by advocatin
260 ibute to this integration and point to areas
in need of study.
261 ation, the transfer of undocumented patients
in need of subacute care to their country of origin.
262 ere revised for patients with cardiac stents
in need of subsequent surgery to recommend delaying elec
263 g management of patients with cardiac stents
in need of subsequent surgery.
264 the current picture of elephant evolution is
in need of substantial revision.
265 ly the perception of stigma among those most
in need of such care.
266 Wetland ecosystems are particularly
in need of such monitoring due to their sensitivity to r
267 We are
in need of suitable data compression algorithms that can
268 f the social "safety net" to catch all those
in need of support and financial assistance are root cau
269 rs to take into account in identifying women
in need of support.
270 dentify patients with cirrhosis who are most
in need of surveillance.
271 decisions, a challenging and complex problem
in need of systematic analysis.
272 hree prognostic groups and predicts patients
in need of targeted therapies.
273 e, such as patients with sickle cell anemia,
in need of the procedure.
274 ced MRCP might also better identify patients
in need of therapeutic ERCP.
275 nd without effective ART for an adult cohort
in need of therapy (2007) and for adults who became elig
276 diet and exercise with high-income patients
in need of these discussions than with low-income patien
277 NASA was
in need of these gas mixtures to ensure the safety of th
278 However, more than 65% of patients
in need of this procedure lack a human leukocyte antigen
279 These predictors may help identify infants
in need of timely eye examinations.
280 sions involve determining which patients are
in need of treatment and which are most likely to benefi
281 differentiate clinically important disorders
in need of treatment from less severe syndromes.
282 (ALL), it is essential to identify patients
in need of treatment intensification.
283 to reduce barriers to help seeking for those
in need of treatment should be increased.
284 tients are increasingly asymptomatic and not
in need of treatment when attending for their routine de
285 avenues for CO delivery to diseased tissues
in need of treatment, without concomitant formation of e
286 accessed treatment, out of an estimated 334
in need of treatment.
287 ted people who had significant liver disease
in need of treatment.
288 try, may be the only option for 70% of those
in need of unrelated hematopoietic stem cell transplanta
289 o determine whether the recommendations were
in need of updating.
290 competitive alternative for children with AL
in need of urgent allograft.
291 ven further limited for symptomatic patients
in need of urgent treatment.
292 cal trials and immunocompromised individuals
in need of vaccination would profit from viral strains w
293 ch theorists may distribute or revise models
in need of validation and experimentalists may search fo
294 Although
in need of validation in less-selected populations, low
295 ctin and heparan sulfate in tissues that are
in need of vascularization so that it can aid in directi
296 will aid clinicians in identifying patients
in need of vigilant follow-up.
297 re on children and young adults, however, is
in need of well-powered randomized controlled trials.