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1 rakizumab; etanercept was given twice weekly in part 1 of reSURFACE 2 and once weekly during part 2).
5 ed selectivity in biological fluids has been in part a driving force in developing future diagnostic
6 t of the microbiota in health and disease is in part a function of the nutrient processing and releas
8 ment in patients with lower acuity; this was in part a result of more favorable donor-recipient match
10 udies strengthen models that posit, at least in part, a SecA dimer-driven translocation mechanism.
11 acrophage-tumour cell proximity was found to in part account for the intratumoral heterogeneity in EG
12 nnervate different brain compartments, which in part accounts for functional diversity of the DA syst
13 ise control of Wnt/beta-catenin signaling is in part achieved by secreted and membrane proteins that
14 ncreasing significantly over the past decade in part as a result of increased recognition of this ser
15 tion required STIM2, but not STIM1, at least in part as a result of redox regulation of cytokine gene
16 CFTR that are regulated by intracellular pH, in part, at ATP-binding site 1 formed by the nucleotide-
18 dest reduction potential of 0.99 V vs NHE is in part attributed to complete charge delocalization acr
19 he ECR coincides with the rapid rise in CO2, in part attributed to upwelling in the Southern Ocean an
20 Tumor recurrence in glioblastoma (GBM) is, in part, attributed to increased epithelial-to-mesenchym
23 Pathway analysis suggested that this might in part be due to an increased body mass index or a redu
24 de-escalation is striking and must, at least in part, be credited to the lack of a clear conceptualis
26 s are oxidized by these enzymes are unknown, in part because intermediates have yet to be observed.
27 cessary for AHR in response to ozone or sHA, in part because it facilitates rapid formation of HA-HC
28 he human host in a latent state for decades, in part because it has the ability to withstand numerous
30 e-modifying therapies for either FTD or NCL, in part because of a poor understanding of how mutations
31 two-dimensional material of great interest, in part because of its high carrier mobility and thickne
32 n a synthetic system have been unsuccessful, in part because of the challenge in preparing a suitable
33 effective against ZIKV-infected mosquitoes, in part because of the ethical concerns related to expos
34 lleran plateaus remains a lingering question in part because of the inherent difficulty in quantifyin
35 orld, however, this right is not guaranteed, in part because of the lack of easily deployable diagnos
36 ironments, but they remain poorly understood in part because of their large, complex genomes, unique
37 versity of viruses remain poorly understood, in part because sparse sampling of the virosphere has co
38 hat racial disparities in health may persist in part because the health of upwardly mobile minorities
39 rch tends to focus on contact heterogeneity, in part because the probability of transmission given co
40 mes of cooperation remains poorly understood in part because their dynamics play out over a timescale
42 yradifurone (FLU), which has been developed, in part, because it appears safer for honey bees than ne
43 sis that the missing causal genes in HCM is, in part, because of an oligogenic cause, wherein the pat
44 oke physical therapy paradigms is challenged in part by a lack of objective tools available to resear
46 alter important predator-prey interactions, in part by altering the location and size of spatial ref
47 metabolic imbalances that could be explained in part by an increase in de novo lipogenesis that resul
48 merization and enzyme activity are regulated in part by binding of purine nucleotides to an allosteri
49 d FRS12 affect these developmental processes in part by binding to the promoters and repressing the e
51 role in the regulation of gene transcription in part by controlling the access of co-activators to th
52 on by RNA polymerase II (Pol II) is dictated in part by core promoter elements, which are DNA sequenc
56 contribution of barrier disruption, mediated in part by defective desmosomes and dysregulated transfo
57 ted TumiD promotes the invasion of T24 cells in part by degrading anti-invasive miRNAs so as to up-re
59 e-triggered behavioural plasticity, at least in part by disinhibiting dopamine neurons in the ventral
60 white matter microstructure impact cognition in part by disturbing the ability of neural assemblies t
61 neurons increases motor neuron excitability, in part by enhancing subthreshold voltage-activated inwa
62 d the growth inhibitory effects of NAE 12:0, in part by enhancing the enzymatic activity of Arabidops
64 cay of the HIV reservoir is slowed over time in part by expansion of the pool of HIV-infected cells.
65 rsistent hyporeplicative state characterized in part by expression of the p16(INK4a) cell-cycle inhib
66 ed disease or resistance to therapy, defined in part by failed response to treatment, increased lengt
68 underlying variability of N2O fluxes, driven in part by fungal respiration and/or iron redox cycling.
69 ss that reveal five discrete stages, defined in part by highly connected transcription factor network
75 these effects induced hypoglycemia, at least in part by increasing insulin and decreasing glucagon ex
79 biological tissues is known to be controlled in part by local geometrical features, such as the curva
81 acterized by compulsive drug intake mediated in part by neuronal and biological adaptations in key br
84 toma and glioblastoma cell lines is mediated in part by PID1, involves NFkappaB, and may be regulated
85 inal cord injury in mice, a benefit achieved in part by reducing macrophage-mediated injury at the le
86 contusion injury in mice, a benefit achieved in part by reducing macrophage-mediated injury at the le
87 andard, are critical for DNA damage recovery in part by regulating ISWI factors loading at DNA lesion
88 coded by CPSF30-L mediates nitrate signaling in part by regulating NRT1.1 expression, thus adding an
90 rial killing by MSC was found to be mediated in part by secretion of cathelicidin and was significant
91 that of other DDK substrates, is determined in part by sequestration of DDK at unfired replication o
93 s and rosettes in the mouse embryo, possibly in part by spatially restricting atypical protein kinase
96 gration, and invasion phenotypes is mediated in part by the constitutive activation of pro-inflammato
97 reterm first birth and CVD was accounted for in part by the development of postpartum chronic hyperte
98 retirement rate of older scientists, induced in part by the elimination of mandatory retirement in un
99 e myosin heads for contraction is controlled in part by the external load on the muscle, so that thes
101 include the Rcf1 protein, are characterized in part by the presence of a conserved motif, (Q/I)X3(R/
103 llin-2 (FBN2) incorporation in microfibrils, in part by transcriptional downregulation of Fbn2 mRNA e
104 coding across the cone synapse, accomplished in part by triggering G-protein betagamma subunits (Gbet
105 e differences between MCs and TCs are caused in part by weaker excitatory and stronger inhibitory cur
106 es: modulation of cerebellar output mediated in-part by long-term depression of parallel fiber-Purkin
107 health partners are approaching this issue, in part, by "reviewing regulatory authority in public he
108 e success of social living can be explained, in part, by a group's ability to execute collective beha
109 r bacteria, a trend which may be determined, in part, by a trade-off between bacterial genome size an
113 ism spectrum disorders (ASD), characterized, in part, by distinct social and communication phenotypes
115 e computational challenge can be dealt with, in part, by endowing RL systems with episodic memory, al
117 phine exerts its rewarding actions, at least in part, by inhibiting GABAergic input onto substance P
118 ctivated protein kinase (AMPK) is regulated, in part, by intracellular calcium, we postulated that AM
120 L41 is poly-ubiquitinated and acts, at least in part, by preventing aggregation and degradation of Ne
123 esponse in association with ketamine occurs, in part, by reversing these neurochemical/physiological
124 B in this zone, which is regulated, at least in part, by the expression of GRF1 and possibly other tr
125 results from failed palliation are limited, in part, by the mammalian heart's low inherent capacity
126 endent phosphoregulation of FOXO4 is primed, in part, by the PI3K/AKT effector axis of oncogenic RAS
130 daptive cytotoxic T-lymphocyte response may, in part, confer resilience to SIV-induced intestinal dam
135 ived considerable attention in recent years, in part driven by renewed interest and opportunities for
136 nization theory has long been controversial, in part due to a dearth of suitably high-resolution tech
137 S and Saos-2 cells to the DeltaICP0 HSV-1 is in part due to an impaired STING pathway.IMPORTANCE The
138 ing, predicting emissions remains difficult, in part due to challenges in disentangling diverse N2O p
139 orsal striatum, is also minimal in the shell in part due to elevated acetylcholinesterase activity.
141 that inflammation after SCI is dysregulated in part due to inappropriate synthesis of proresolving l
142 from antibiotic exposure affects bee health, in part due to increased susceptibility to ubiquitous op
143 orlistat significantly diminished stemness, in part due to induction of endoplasmic reticulum (ER) s
147 reprogrammed glutamine metabolism, at least in part due to the glutathione pathway, an efficient cel
149 between the macroeconomy and birth outcomes, in part due to the methodological challenge of distingui
150 suppressor protein p53 is kept at low levels in part due to ubiquitination by MDM2, a process initiat
153 al PI3Kdelta/CK1epsilon inhibitor, which may in part explain the clinical activity of TGR-1202 in agg
154 altered TIEG1 expression and/or activity may in part explain the observed osteopenic phenotype of TIE
157 zing data from a household cohort maintained in part for study of influenza vaccine effectiveness (VE
159 ctional importance of palmitoylation results in part from a dramatic increase in ARL13b stability, wh
160 between the Syt1 and Syt7 C2A domains arise in part from apparently conservative residue substitutio
162 ch as addiction and schizophrenia, may arise in part from dysregulated activity of ventral tegmental
163 I-defined overweight risk paradox may result in part from failing to account for central adiposity, r
164 by promoter methylation, resulting at least in part from increased expression of the DNA methyltrans
165 tumor glioblastoma multiforme (GBM) results in part from its strong propensity to invade surrounding
166 e been proposed, but they lack confirmation, in part from the absence of reliable structural informat
167 how that the seasonal-mean signature results in part from year-to-year variations in persistent, quas
168 These precursors were derived, at least in part, from CD11c(dim)CD11b(int)Gr1(-) lung-resident m
170 vels is therefore likely to result, at least in part, from the epigenetic regulation of MYBL1 express
173 rtical thinning during adolescence, which is in part governed by evolutionary novelty and functional
174 n protein occludin (OCLN), explain, at least in part, HCV's limited ability to enter mouse hepatocyte
175 ess, suggesting that neuronal VGF, expressed in part in inhibitory interneurons, regulates depression
176 regulation in various nonthyroid tissues was-in part-induced by thyroid (hormone)-dependent signaling
177 Tg mice, suggesting that sortilin, at least in part, inhibits forebrain tau prion replication in viv
179 results suggest that OVX-induced bone loss, in part, is a result of increased osteoblastic cell sene
182 of fucose substitutions in C. elegans, which in part may be due to different methodological approache
185 )CD25(+)Foxp3(+) regulatory T cell (Treg) is in part mediated by TGFbeta-induced inhibition of inosit
188 40% and has recently increased in frequency in parts of Kenya, yet it appears to be absent from west
189 of the repetitive use of objects or interest in parts of objects' and rs2898883 (P<6.8 x 10(-9)), whi
190 ve negative effects on some mangrove forests in parts of the Indo-Pacific that will exacerbate other
191 ompromises the availability of such dialysis in parts of the world where financial resources are cons
193 bit intrinsic promoter activity that depends in part on the hexameric domain, we assayed the transcri
194 d to skin cancer, whose mutagenicity depends in part on their frequency of formation and deamination.
196 o confirmed that bottomfish relied, at least in part, on a benthic food web and identified the incorp
198 e characteristics have been shown to depend, in part, on the intrauterine position during development
199 based their decision to take PrEP, at least in part, on their perceived risk of incident HIV infecti
200 focal breast cancer susceptibility, at least in part, originates from region-specific myoepithelial p
202 at high risk of cardiovascular disease (CVD) in part owing to hypertriglyceridemia and low high-densi
203 nt of CD8+ T cells to the tumor is impaired, in part preventing containment or elimination of the tum
204 vitro EndMT and adipogenesis of HemECs have, in part, recapitulated the natural history of hemangioma
205 axis or therapy exists for these toxicities, in part reflecting an incomplete understanding of mechan
206 tuberculosis drug bedaquiline has been slow, in part reflecting concerns about spread of bedaquiline
208 isplay different mechanisms of action, which in part reflects the requirement for capsid function at
209 , our data suggest that this efficacy may be in part related to an effect on PD-L1(hi) B cells and Tf
210 the presence of mycolic acids (MAs), which, in part, render the bilayer extremely hydrophobic and im
212 However, although neurally derived Shh is in part responsible for the dependence of taste cell ren
213 hat differential 2A(pro) activities explain, in part, strain-dependent host responses and diverse RV
214 COS surface expression and rescues, at least in part, T follicular helper numbers and the abnormal Ab
215 ow-induced atherosclerosis through, at least in part, targeting cell cycle regulator cyclin A and con
217 t within a single individual and may explain in part the heterogeneous fates of metastatic lesions of
218 cinogenic effects that can explain, at least in part, the complex relationship between exposure to UV
219 -sensitive tissues and may explain, at least in part, the increased risk of type 2 diabetes in p.P50T
223 iation, compared to many single-factor ECMs, in part through an integrin beta3-mediated pathway.
224 lpha-ketoglutarate (alphaKG)-induced events, in part through changes in DNA and histone methylation s
227 ify the forkhead transcription factor Foxh1, in part through Eomes, to be critical for the formation
228 novani evades host immune response, at least in part through inhibition of Wnt5a signaling, revamping
229 s regulation of hippocampal-dependent memory in part through inositol 1,4,5-trisphosphate and brain-d
230 ury initiates important regenerative signals in part through NF-kappaB-mediated signaling that activa
231 genes independently of methylation changes, in part through regulation of the gene encoding the tran
232 promoting post-selection thymocyte survival in part through stabilization of the pro-survival protei
233 uscarinic receptor-3 (M3R)-dependent manner, in part through suppression of yes-associated protein (Y
234 preferentially retained by the mother cell, in part through tethering to mitochondria, while the dis
236 in intron removal in SMA promote DNA damage in part through the formation of RNA:DNA hybrid structur
237 rovide beneficial anti-inflammatory effects, in part through their conversion to bioactive metabolite
241 also show that TEX19.1 likely acts, at least in part, through promoting the activity of the E3 ubiqui
242 ct of fasting-mimetic diets may be mediated, in part, through SIRT3-directed blunting of NLRP3 inflam
243 Structured knowledge is thought to form, in part, through the extraction and representation of re
244 sphorylation is temporally ordered, at least in part, through the sequential expression of different
245 gh clinical trial design is challenging, due in part to a lack of robust biomarkers with predictive v
246 the most hydrothermally active areas, owing in part to a low and patchy density of vent-endemic faun
247 d during a critical developmental period due in part to a perturbation in BDNF-TrkB signaling, and co
248 e of atlazy1,2,4 mutants may be due at least in part to a reversal in the gravitropism mechanism.
250 ion in the display of these behaviors is due in part to age and sex differences in AVP and OT synthes
255 ERalpha-negative breast cancer due at least in part to epigenetic reactivation of ERalpha, which in
259 thought to result from beta-cell injury due in part to pancreas exocrine damage and lipofibrosis.
260 gs suggest that hospital quality contributes in part to readmission rates independent of factors invo
261 TREM2 function remains elusive, however, due in part to the absence of conclusive information regardi
262 een linked to neurodegenerative diseases due in part to the central role of mitochondria in metabolis
263 ported with increasing frequency, attributed in part to the cessation of smallpox vaccination and con
264 biological barriers remains incomplete, due in part to the challenge of tracking nanoparticle fate i
266 lic, regulatory, and signaling pathways, due in part to the high tunability of their bound and unboun
267 at metastasized cells are less migratory due in part to the post-metastatic downregulation of S100A4
268 sparities in HIV continuum of care are owing in part to the unique developmental issues of adolescent
269 that the oncogenic activity of PRKCI relates in part to the up-regulation of TNFalpha to promote an i
270 latively enhanced efficiency is attributable in part to the use of a highly concentrated pomegranate
271 ange of AP waveforms and firing rates, owing in part to the use of an iterative algorithm for the det
272 ccines have not been successful to date, due in part to the virus's high sequence variability leading
273 ncreasing impact in healthcare settings, due in part to this organism's resistance to many antimicrob
274 genes has remained difficult to address, due in part to unique challenges related to tRNA sequencing.
275 This adaptation appeared to be related, in part, to a putatively advantageous allele for the per
276 occurred with IL-2R(lo) Tregs and was shown, in part, to be the consequence of exposure to IL-12.
277 fication of anaphylaxis deaths due, at least in part, to difficult coding under the International Cla
278 cated that this impairment was due, at least in part, to ineffective use of negative feedback to guid
279 IL-2Ralpha expression by Treg cells was due, in part, to integrin LFA-1-mediated interactions between
281 ly other cleaved TM helices may be designed, in part, to make their backbones accessible for cleavage
284 f musical tone combinations is due, at least in part, to the biological advantages that accrue from r
285 besity-associated insulin resistance is due, in part, to the compromise of hepatic autophagy, a proce
286 re, we propose that these phenomena are due, in part, to the deployment/secretion of a "decoy flare,"
287 odifications is not fully understood, owing, in part, to the difficulty associated with reconstitutin
288 bstituents have received less attention due, in part, to the lack of practical synthetic strategies.
290 and temperature sensitivity is attributable, in part, to their compensatory effects on C uptake, wher
293 ast function appears to be mediated at least in part via interactions with key components of the Notc
296 ders have adapted to high altitude, possibly in part via the selection of genetic variants associated
297 th, and indeed, MYC selects for this pathway in part via transcriptional regulation of PKCalpha and I
298 in attenuated TNBS-induced colitis, at least in part, via inhibition of TLR4/MyD88 signaling cascade
299 promotes mitochondrial elongation, at least in part, via suppression of the mitochondrial fission pr
300 Because these impairments are associated in part with exposure to poorly processed cassava as mea
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