ライフサイエンスコーパス: in situ

1 n active auxin analogue, which can be tagged in situ.

2 tify adenosine-to-inosine-edited transcripts in situ.

3 e brain-wide accumulation of supplemented Li in situ.

4 archaea possess and express novel mcrA genes in situ.

5 ters that are amenable to chemical reactions in situ.

6 of these niches remains to be characterized in situ.

7 and 9:1:2 FTB), observed for the first time in situ.

8 allows sophisticated markerless gene editing in situ.

9 ld be filtered and colorimetrically analyzed in situ.

10 ks between viruses and their potential hosts in situ.

11 iety (siRNA-L2), which rapidly binds albumin in situ.

12 tial distribution maps for molecular species in situ.

13 onal reconstruction and analysis of caveolae in situ.

14 ect of a radionuclide-labeled EGFR inhibitor in situ.

15 asure bacterial population replication rates in situ.

16 MR in the remaining 26 patients with valves in situ.

17 hnical challenges in probing these materials in situ.

18 urrent RD was seen whilst mixed oil remained in situ.

19 terval cancers were identified (181 total-54 in situ, 125 invasive, and two status unknown).

20 Here, using in situ (18)O isotope labelling mass spectrometry, we pr

21 To follow the behavior of dHSCs in situ, a Gprc5c-controlled reporter mouse was establis

22 t the need for transition metal catalysis or in situ activation of the nucleophile.

23 This report provides evidence of the in situ activity of microbes using extracellular substra

24 um to the nitrile function, cyclization, and in situ acylation with di-tert-butyldicarbonate.

25 This in turn enables precise in-situ alignment detection, for the first practicable r

26 ilizes total chromatin, CUT&RUN is performed in situ, allowing for both quantitative high-resolution

27 ontrolled reduction of the hydrazone with an in situ allylic strain controlled retro-ene reaction of

28 subsequent easy detection of the product by in situ ambient ionization mass spectrometry.

29 In situ analyses were performed on glutaraldehyde-fixed

30 In contrast, particle diffusometry permits in situ analysis of DNA microviscosity with short measur

31 work, a microfluidic device is developed for in-situ analysis of pesticide concentration detected via

32 tly reduced in precancerous ductal carcinoma in situ and all breast cancer subtypes.

33 Here, an in situ and ex situ electron microscopy investigation of

34 tween the different images modes may be done in situ and extremely rapidly, allowing for simple imagi

35 In situ and in other experimental systems, the enzyme ex

36 er understand this phenomenon, we used novel in situ and in vitro preparations based on paired extrac

37 lcium carbonate precipitation and associated in situ and in-service water distribution pipeline leak

38 n techniques to probe molecular architecture in situ and integrate information from diverse data stre

39 ost risk factor associations are similar for in situ and invasive cancers and may influence early sta

40 Here we present Breaks Labeling In Situ and Sequencing (BLISS), featuring the following:

41 of the different components of this machine in situ, and the spatial distribution of the substrates

42 particles can undergo oxidation or reduction in situ, and thus the redox species are not what are obs

43 Here, by performing in situ atomic-scale transmission electron microscopy, w

44 (Al, Cu, Fe, Mn, Zn) to the solution on the in situ atomization and excitation processes occurred du

45 terface is characterized both with APXPS and in situ attenuated total reflectance Fourier transform i

46 Using in situ autophosphorylated protein, we expand on the kno

47 des a novel generic method to understand the in situ battery chemistry without any further sample pro

48 end group fidelity is further exemplified by in situ block copolymerization upon sequential monomer a

49 photoredox initiated hole catalysis and the in situ Bronsted acid activation of the carbonyl compoun

50 h i-PrMgCl, or aryllithium reagents prepared in situ by bromine/lithium exchange with n-BuLi are comp

51 5 months to changes in habitat availability in situ by comparing densities and feeding rates on arti

52 ignard solutions, Grignard reagents prepared in situ by halogen/magnesium exchange with i-PrMgCl, or

53 is unresolvable from co-deposited magnetite in situ by other electrochemical techniques and is undet

54 Despite this, when held in in situ cages with predators, those larvae that previous

55 so introduce an empirical model to calculate in situ carbonate ion concentrations from [CO3(2-)]spec.

56 nsformation, and the reaction is amenable to in situ carboxylic acid activation.

57 s at the nanoscale, with special interest on in situ catalysts and biosensing.

58 lial neoplasia grades 2/3 and adenocarcinoma in situ (cervical intraepithelial neoplasia grade 2 or h

59 detection, consisting of a high-sensitivity in situ channel with signal-to-noise of 10(5) and a lowe

60 We utilize some advanced in situ characterisation techniques including synchrotro

61 cantly, SECM-based CV will be useful for the in situ characterization of various electrodeposited com

62 Whereas in situ chelation of PyED leads to considerable degradat

63 ed to assess whether a modified approach for in situ chemical oxidation (ISCO) (with MgO2 and Fe2O3 p

64 Persulfate (S2O8(2-))-based in situ chemical oxidation (ISCO) has gained more attent

65 ulture, are comprehensively characterized by in situ co-examination of chromosome aneuploidy by FISH

66 model of intracranial hemorrhage induced by in situ collagenase type VII injection.

67 xamine, we use recently developed methods of in situ computational microscopy to recast the enormous

68 also affects interpretation of results from in situ continuous treatment processes.

69 We found that prior in situ contraction of m.

70 The in situ control of redox insult in human organs is of ma

71 etely predetermined, leaving little room for in situ control.

72 of alcohols to their beta-amino analogs (via in situ conversion of alcohols to imidates, directed C-H

73 f supramolecular polymer networks through an in situ copolymerization of acrylamide and functional mo

74 ns, which we have followed using an original in-situ crack opening technique.

75 (P < .001) and presence of ductal carcinoma in situ (DCIS) (HR, 2.15; 95% CI, 1.36-3.38; P = .001) w

76 R2-positive status in human ductal carcinoma in situ (DCIS) lesions and invasive breast cancers as we

77 ntation of that cancer, for ductal carcinoma in situ (DCIS), invasive breast cancer, and all breast c

78 residual invasive cancer or ductal carcinoma in situ (DCIS).

79 RhCl3 and graphene oxide with NaBH4 and the in situ deposition of the metal nanoparticles on the 2D

80 , a painless, fast and direct method for the in situ detection of H. pylori remains a challenge, main

81 coli DNA aptamer (Kd 14nM), screened by new in-situ developed SELEX method using phenylboronic acid

82 was investigated using flow tube reactor and in situ Diffuse Reflectance Infrared Fourier Transform S

83 tuitary-infiltrating lymphocytes proliferate in situ during AH, providing a previously unknown pathog

84 The analysis of the scattered light allows in situ dynamic monitoring of the electrodeposition of s

85 that the higher-conducting states arise from in situ electrochemical conversion of the dative Au<--N

86 Using in situ electrochemical strain microscopy (ESM), we demo

87 Here, using in situ electron microscopy, we show how gold and silver

88 n at atmospheric pressure, by using advanced in situ electron microscopy.

89 separates 25(OH)D3 from its binding protein in situ, eliminating the need for sample preparation.

90 in 2, 4 and 8% NaOH solutions and subsequent in-situ enzymatic hydrolysis were thoroughly characteriz

91 The in situ enzyme activity evaluation was based on the abil

92 In situ evidence of active photoarsenotrophic microbes w

93 Here we use a novel in situ experimental method involving olivine micro-reac

94 Using a visco-plastic law derived from in-situ experiments, the experimentally measured and cal

95 The in situ expression of solute transporters indicates that

96 The in situ extended X-ray absorption fine structure analysi

97 removing projection artifact while retaining in-situ flow signal from real blood vessels in deeper la

98 The process proceeds quickly (30-45 min) via in situ formation and intramolecular cyclization of alky

99 h azide anions provides acyl azides, through in situ formation of diazido ketones.

100 In-situ formation of Cr7C3 nanostructures at the MWCNT/C

101 , promoted by hydrogen-bonding to either the in situ formed ammonium moiety or the hydroxyl group, wa

102 f cyclopropylketone arylhydrazones generated in situ from arylhydrazine hydrochlorides and ketones le

103 cyclic alkenes with nitrile oxides generated in situ from the corresponding aldoximes using organohyp

104 earrangement of a sulfonium ylide, generated in situ from the coupling of a copper-carbene with a spi

105 the nanogel via a membrane vesicle templated in situ gelation process, whereas the redox-responsivene

106 o enhance the delivery of GAG, we created an in situ gelling rectal delivery system using silk-elasti

107 an asymmetric reductive transposition of the in situ generated allylic diazene.

108 We report here a unique example of an in situ generated aluminum initiator stabilized by a C2-

109 m in size), together with the rGO sheets and in situ generated amorphous carbon that serve as a dual

110 The in situ generated aryne acts as a two-atom component, an

111 hydroxy/aryl)imino-beta-oxodithioesters with in situ generated Cu-carbenoids of diazocarbonyls.

112 iF coating on reactive anode materials, with in situ generated fluorine gas, by using a fluoropolymer

113 the nucleophilic attack by benzamidine on an in situ generated imine intermediate has been proposed.

114 ade between a vinyl p-quinone methide and an in situ generated isomeric diene promoted by either Lewi

115 s catalyst, which may be associated with the in situ generated nickel-iron oxide/hydroxide and iron o

116 Active methylene compounds react with in situ generated nonstabilized azomethine ylides via th

117 can be used in a domino one-pot reaction via in situ generation of a directing group.

118 ive (ammonium) binding site, stabilizing the in situ generation of benzhydryl cation and oxonium ion

119 data support a molecular mechanism in which in situ generation of nonlamellar lysophospholipids by A

120 -step mechanistic sequence involving initial in situ generation of the diethoxymethyl radical from di

121 The method involves the in situ generation of the key intermediate [E....._ (S..

122 tion/reduction in 0.1 M HClO4 was studied by in situ grazing-incidence small-angle X-ray scattering a

123 n was more frequent in the invasive than the in situ group (P = 4.93 x 10(-8)).

124 en-reduction electrocatalyst is prepared via in situ growth of bimetallic zeolitic imidazolate framew

125 on a unique material system that allows for in situ growth of bismuth nanoparticles from the precurs

126 dsDNA by peptide nucleic acid (PNA) and the in situ growth of electroactive polymers through the sur

127 375 degrees C over H-SAPO-34 catalyst via an in situ halogenation (chlorination/bromination) protocol

128 to track cells that have undergone apoptosis in situ has revealed a division of labor among the tissu

129 romising technology to address this issue is in situ healing of compromised membranes via healing age

130 Here we use in situ heating in a scanning transmission electron micr

131 By performing in situ Hi-C in TGCT cells, we provide evidence for a ne

132 Here we propose in situ Hi-C method named Bridge Linker-Hi-C (BL-Hi-C) f

133 Kinetic studies using in situ high pressure IR (HPIR) and the reaction progres

134 lindromic repeats (CRISPR)-Cas9 platform for in situ high-content functional analysis of RREs.

135 Here by employing in situ high-pressure synchrotron radiation X-ray diffra

136 d and cost-effective means to detect targets in situ; however, existing LFA formats (predominantly sa

137 YAP1 in human eye development, we performed in situ hybridisation utilising human embryonic tissue,

138 esised that EGFR copy number by fluorescence in-situ hybridisation (FISH) can identify patients most

139 F amplification was assessed by fluorescence in-situ hybridisation of two cores of breast tumour tiss

140 ranscription and replication, a fluorescence in situ hybridization (FISH) protocol was established to

141 The development of fluorescence in situ hybridization (FISH) technologies enables the qu

142 EGFR CNG was determined by fluorescent in situ hybridization (FISH) using prespecified criteria

143 Fluorescence in situ hybridization (FISH) will be required to identif

144 ) or -negative (HER2-) based on fluorescence in situ hybridization (FISH)-supplemented immunohistoche

145 Fluorescence in situ hybridization analysis mapped the EPSPS gene to

146 Pyrosequencing and fluorescence in situ hybridization analysis revealed that denitrifyin

147 In situ hybridization analysis revealed that Fusobacteri

148 ncident virologic clearance was confirmed by in situ hybridization and a failure of disease to recur

149 ele-specific RNAseq, nascent RNA-fluorescent in situ hybridization and immunofluorescence), we show h

150 tides derived from this precursor using mRNA in situ hybridization and immunohistochemistry revealed

151 Cluster analysis, in situ hybridization and RNAi assays indicate that male

152 ice fed a polysaccharide-rich diet, and (ii) in situ hybridization and spectral imaging analysis meth

153 RNA levels, assessed by quantitative PCR and in situ hybridization at 1, 4, 7, and 15 days after the

154 ning events were then tested by fluorescence in situ hybridization during T-cell activation.

155 As fluorescence in situ hybridization has limitations regarding the reso

156 es those loci by DNA sequential fluorescence in situ hybridization in fixed cells and resolves their

157 in ovaries was also detected by fluorescent in situ hybridization in G. f.

158 Detailed in situ hybridization studies of tip-enriched prediction

159 ate Pheno system uses automated fluorescence in situ hybridization technology with morphokinetic cell

160 can cichlid fish Astatotilapia burtoni using in situ hybridization to label vesicular glutamate trans

161 Fluorescent in situ hybridization was performed to determine the rol

162 Immunohistochemistry and in situ hybridization were used to determine viral capsi

163 roadly applicable technique called 'Ligation in situ Hybridization' ('LISH'), which is an alternative

164 rs are already available (e.g., fluorescence in situ hybridization, 16-S rRNA gene amplicon sequencin

165 w levels of SIV RNA in the brain as shown by in situ hybridization, and generally was observed in ani

166 data from karyotype, DNA index, fluorescence in situ hybridization, and polymerase chain reaction scr

167 Here, we used classical pharmacology, in situ hybridization, immunohistochemistry, and the Dau

168 s, GXD collects and integrates data from RNA in situ hybridization, immunohistochemistry, RT-PCR, nor

169 Using single-cell RNA-Seq and multiplexed in situ hybridization, we show here that a single marker

170 genetic risk, as assessed using fluorescence in situ hybridization.

171 lized this expression in mechanosensilla via in situ hybridization.

172 unophenotype, cytogenetics, and fluorescence in situ hybridization.

173 tages of C57BL/6J mice by using double-label in situ hybridization.

174 ncreased in Tmem107(-/-) animals as shown by in situ hybridization.

175 In situ hydrogel softening (from ca. 14 to 3.5 kPa) led

176 In situ hydrothermal-based productivity combined with si

177 rument setup and operation are discussed and in situ image correlation is demonstrated on a lithium t

178 ns categorically rule out the possibility of in situ imine formation followed by ring-closing, but su

179 conjunctival tissues was also assessed using in situ immunohistochemical analysis.

180 teins that can be quantified in single cells in situ impede advances in our deep understanding of nor

181 The charge-tagged carbene was generated in situ in a tandem mass spectrometer by decarboxylation

182 ce of gold nanoparticles (AuNPs) synthesized in situ in alginate, a natural polysaccharide.

183 nts were compared with those with the device in situ in an attempt to identify factors associated wit

184 ed a precise visualization of the heteromers in situ in combination with sophisticated genetically mo

185 (irrespective of their chemical reactivity) in situ in the living body.

186 the ability to deploy E-AB sensors directly in situ in the veins of live animals, achieving micromol

187 of individual subdomain folding transitions in situ, in the context of the whole molecule.

188 thesis of thiochromenes through Cu-catalyzed in situ incorporation of sulfur.

189 ctive adsorption constants are obtained from in situ infrared spectra.

190 the downstream targets of ZNF804A, a Duolink in situ interaction assay confirmed genes from our RIP-S

191 In situ interactions were observed in proteins throughou

192 I-III respirasome and enabled prediction of in situ interfacial regions of the complexes.

193 rously structured PEDOT coating, paired with in situ ion gel electrolyte synthesis, gives enhanced el

194 nt-reported outcome (PRO) measures for laser in situ keratomileusis (LASIK) are needed.

195 Here we show, by using in situ Kr ion irradiation in a transmission electron mi

196 vasive ductal carcinoma and ductal carcinoma in situ (largest focus, 3.5 cm).

197 lecules extraction can be performed directly in situ, leaving the object unchanged and intact.

198 l organization of phytoelements according to in situ light environments.

199 In situ lipid synthesis for protein reconstitution techn

200 Here, we employ in situ liquid-cell transmission electron microscopy (LC

201 The in situ maturation of UQCRFS1 produces N-terminal polype

202 Implementation of more advanced in situ measurement devices could be easily accommodated

203 orth Sea, from 1988 to 2013, estimated using in situ measurements of chlorophyll and underwater light

204 d our methodology paves the way for rigorous in situ measurements of the behavioral rules that underl

205 and is poorly quantified by most models and in situ measurements.

206 l-time diagnostic tool for visualization and in-situ measurements of "blind" processes.

207 Hence, these electrodes allow for the in situ mechanistic and kinetic characterization of elec

208 We herein introduce an improved in situ membrane healing method using amine-functionaliz

209 rmulation offers significant potential as an in situ method for oxygen generation to enhance the effi

210 In situ methylene capping is introduced as a practical a

211 supplementation, although composition of the in situ microbiota remained unchanged.

212 d on the continuous flow of solvent using an in situ microextraction device in which solvent moves th

213 ical degradation of trichloroethene (TCE) by in situ minerals, and C2H2 is known to inhibit bacterial

214 Melanoma in situ (MIS) is increasing in incidence, and expert con

215 ure of the selected zwitterions allows their in situ modification and affords a route to chemically t

216 of elastic deformation could be designed for in situ monitoring and fine control of fluid flow in fle

217 This paper includes a novel strategy for in-situ monitoring the processing stages of composites b

218 Cas9-mediated, high-throughput, saturating in situ mutagenesis permits fine-mapping of function acr

219 Using in situ neutron diffraction and meta-dynamic simulation,

220 N-oxyl) is described, which undergoes facile in situ noncovalent immobilization onto a carbon cloth e

221 Therefore, an in situ observation of chemical and mechanical character

222 inography imaging technique was employed for in-situ observation of the microstructure evolution duri

223 The in situ observations identify complex dynamic changes in

224 We conducted in situ observations of cleaning interactions between bl

225 The in situ observations, combined with large-scale reactive

226 Based on the in situ-obtained UV/Vis absorption spectra during the re

227 , we describe a CRISPR affinity purification in situ of regulatory elements (CAPTURE) approach to unb

228 Next, a brief overview of emerging in situ/operando approaches demonstrates new options for

229 ics of perovskite crystals is scrutinized by in situ optical microscopy tracking to understand the cr

230 treatment of 2727 patients diagnosed with an in situ or invasive primary melanoma over a 12-month per

231 cancers in each subset were ductal carcinoma in situ or stage I.

232 3,2-b]chromen-9-ones have been developed via in situ or stepwise intramolecular heteroannulation of n

233 s in the low- to midrange of hydrophobicity, in situ passive sampling of strongly hydrophobic polychl

234 ulfurospirillum spp. are key contributors to in situ PCE reductive dechlorination under low pH condit

235 iciently function to generate singlet oxygen in situ (PhiDelta approximately 20 %) and has appropriat

236 Using in situ photoemission spectroscopy and online product an

237 strategy that preserves their integrity and in situ physiological state, e.g. viability, cultivabili

238 next-generation DNA sequencing reactions and in situ point mutation detection assays in preserved tum

239 Using an in situ preparation method, individual compartments are

240 Herein we introduce a multichannel in situ pressure measurement system that allows for the

241 example, the possibility of in-line or even in situ process control in semiconductor industry.

242 nse to submaximal rates of nerve stimulation in situ producing significantly higher absolute forces a

243 at the two processes are in balance and that in situ production is unlikely an important net source o

244 ts their potential for electron transfer and in situ production of HO(*) using structure-activity rel

245 s peroxidase-catalyzed, spatially restricted in situ protein biotinylation with RNA-protein chemical

246 precipitation assays, immunoblotting, and an in situ proximity ligation assay to characterize the tru

247 In this in situ radionuclide tracer test, the environmental beha

248 stem can be optimised to enable simultaneous in-situ Raman spectroscopy monitoring of 2D dispersed fl

249 emory by engineered mutagenesis with optical in situ readout (MEMOIR), is based on a set of barcoded

250 nt responses of the UPSS are validated using in situ real-time atomic-force microscopy, representing

251 Furthermore, in situ real-time confocal laser scanning microscopy ima

252 r supplies for a range of applications, with in situ release of the required hydrogen from a stable l

253 ating process of perovskites is investigated in situ, revealing that thin-film formation is mediated

254 specific sensor fouling may enable long-term in situ sensor array operation in low resource settings.

255 e mass spectrometers (SPMSs), which generate in situ single particle composition data, are excellent

256 sm of water sorption were corroborated using in situ single-crystal X-ray diffraction (SCXRD) studies

257 In situ single-crystal X-ray diffraction analysis was ca

258 In situ small/wide-angle X-ray scattering and electron m

259 a combination of kinetic, thermodynamic, and in situ spectroscopic measurements show that when group

260 Kinetic, mechanistic, and in situ spectroscopic studies establish that Pd(II)-medi

261 Here we utilize in situ spectroscopy and microscopy to identify and char

262 is unique high-valent state may be probed by in situ spectroscopy.

263 In situ structural information about this highly abundan

264 In-situ structural investigations were performed using c

265 mography(10) to reveal the three-dimensional in situ structure of a T4bP machine in its piliated and

266 xtractable C70-C100 region are determined by in situ studies of defined clusterfullerenes under typic

267 In situ sXAS studies of neutral-pH OER catalysts indicat

268 room temperature while acquiring consecutive in situ synchrotron diffraction patterns from the beginn

269 By using in situ synchrotron-based small/wide angle X-ray scatter

270 Ambient pressure in situ synchrotron-based spectroscopic techniques have

271 l Vapour Deposition (RCVD) technique for the in-situ synthesis of large scale carbon-coated non-magne

272 addition to the introduction of an improved in situ TEM biasing technique.

273 of the Southern Ocean, from net samples and in situ temperature records collected during the Discove

274 GaSb were systematically investigated using in situ temperature-dependent electrical resistivity mea

275 ronment and capable of metabolic activity at in situ temperatures, possessing a suite of stress respo

276 l analysis correlated high tumor uptake with in situ TF expression.

277 oproteomic analyses to identify and quantify in situ the phosphorylation sites in the NaV1.5 proteins

278 by epithelial ovarian and lung cancer cells in situ This finding prompted us to study the role of HD

279 defects using electron and X-ray techniques, in situ three-dimensional imaging of defect dynamics rem

280 in a vesicle-like structure that is captured in situ through a simple crosslinking reaction.

281 uct, and demonstrate the potential for rapid in situ through-container analysis; achieving unequivoca

282 ge process on both CaAl LDHs was followed by in situ time-resolved synchrotron-based X-ray diffractio

283 We employ in-situ transmission electron microscopy and operando X-

284 s, heat-activated persulfate may be a useful in situ treatment for sites contaminated with polyfluoro

285 t one invasive tumor and 1,943 subjects with in situ tumors only.

286 process of this phase-change was followed by in situ variable temperature powder X-ray diffraction.

287 2+) on a dynamic library of imines generated in situ via condensation of benzaldehyde and 2-picolylam

288 ted acid-catalyzed process using TfOH formed in situ was ruled out by control experiments.

289 n cellular models of breast ductal carcinoma in situ, we reveal a link between filopodia formation at

290 ancers (33 invasive and 12 ductal carcinomas in situ) were diagnosed, 43 were seen with MR imaging an

291 criptional activity from the NtPDR1 promoter in situ with a reporter gene and found that, although Nt

292 spartate aminotransferase, which was reacted in situ with alpha-methylaspartate.

293 g-detected cancers were invasive rather than in situ with DBT (74.2% [287 of 387] vs 66.0% [260 of 39

294 f pathological tau aggregates to be measured in situ within 24 h in the presence of picomolar concent

295 Analysis of chemical reactivity, in situ X-ray absorption spectroscopy, and density funct

296 In situ X-ray diffraction analysis reveals that the mate

297 In situ X-ray diffraction experiments can provide insigh

298 ion/extraction processes, as demonstrated by in situ X-ray diffraction, galvanostatic intermittent ti

299 k of the catalyst during the reaction, quasi in situ X-ray photoelectron spectroscopy showed that the

300 Using immunoblotting, in situ zymography, and immunofluorescence, we found tha