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1 -specific GPP was independent of temperature in spite of a 20 degrees C thermal gradient.
2                                              In spite of a continued impairment in spike repolarizati
3 infection was greater than to wild-type RSV, in spite of a decreased viral load, and when IL-1beta wa
4 herefore, Xist-null mice can develop to term in spite of a deficiency of dosage compensation.
5 were still established in migration mutants, in spite of a dramatic rostrocaudal repositioning of the
6                                     However, in spite of a growing body of literature on the potentia
7 ow the islet facilitates inhibitory activity in spite of a heterogeneous cell population, as well as
8 ite with an affinity similar to that of sbmA in spite of a lack of sequence similarity between these
9 face energy of the most stable IrO2 surface, in spite of a large lattice mismatch, and has no impurit
10                                              In spite of a liking for and ability in clinical medicin
11  IL-1beta response to RSV DeltaSH is greater in spite of a lower viral load, which contributes to the
12 their tails as flexible grasping appendages, in spite of a rigid bony armor that fully encases their
13 responders were also clinical nonresponders, in spite of a transient improvement in some cases.
14                                              In spite of all available medical and surgical intervent
15                                              In spite of an adverse role of missed cleaved peptides o
16    In this report, we provide evidence that, in spite of an apparent lack of phagocytic activity, bas
17          The restoration of fertility occurs in spite of an autosomal and X-linked genome that is mos
18 f traces of DNA of the allergenic components in spite of an excess of the other DNA templates.
19 e to maintain the regenerative capacity even in spite of an ischemic injury.
20 s systems: How is robust modulation achieved in spite of animal-to-animal variability and degenerate,
21 aintain generally stable allograft histology in spite of apparently active humoral allo-immune respon
22                                              In spite of attempts by healthcare systems to encourage
23                                              In spite of attempts to develop vaccine candidates and a
24 accharide is reported, which, interestingly, in spite of being considerably structurally similar with
25                                              In spite of being recognized as the top-most differentia
26                                              In spite of being widely used for in liquid biosensing a
27  and possible resilience in control subjects in spite of biological overlap.
28 boundaries of gene expression form precisely in spite of biological variation/noise.
29                                              In spite of both variants ablating a portion of the cata
30  suggesting an involvement in early control, in spite of CD4 T cell susceptibility to HIV infection.
31 ated in UC patients at formerly active sites in spite of clear histological recovery.
32                                              In spite of comparable amounts of HIV attached to monocy
33 resent and future treatment regimens for HCV in spite of concomitant increased risk of anemia.
34                                              In spite of considerable research effort over the years,
35 ree CML patients in chronic residual disease in spite of continuous treatment with imatinib, all of t
36  site have similar neutralization activities in spite of converse kinetic binding parameters.
37          Here we document boundary stability in spite of critical expansions of the CGG trinucleotide
38 ect pancreatic cancer cells that proliferate in spite of cytotoxic drug treatment.
39 as not found widespread industrial adoption, in spite of decades of active research, because the chal
40                                              In spite of decades of linkage and association studies a
41                                              In spite of decades of research, mineral growth models b
42 ctral vicinity of exact embedded eigenvalues in spite of deep surface modulation and vertical asymmet
43                                              In spite of dramatically reduced virulence, the designed
44 ing for crossover invariance (constant cM/kb in spite of DSB hotspots).
45                                     However, in spite of effective chemotherapeutic agents, neuropath
46                                This occurred in spite of enhanced plasma CXCL1 levels as well as neut
47 water are much faster than those by ethanol, in spite of ethanol's more rapid spread across the elytr
48                                              In spite of evidence for rampant incongruence among indi
49                                              In spite of existing opinions about the anticancer actio
50                                     However, in spite of exposure to multiple viral variants, the T c
51                                              In spite of extensive efforts employing existing protoco
52                                              In spite of extensive efforts over decades an experiment
53                                              In spite of extensive recent progress, a comprehensive u
54  recruitment have received little attention, in spite of forecasted forest expansion.
55                                              In spite of good exposure, twice-a-day treatment with 17
56                                              In spite of great advances in the design of curative tre
57 s that seek to provide genotypic information in spite of great proportions of missing data.
58                                              In spite of greatly increased in vivo attenuation, some
59 n-circuit voltage (Voc) and fill factor (ff) in spite of having comparable short-circuit current dens
60 otropic columnar liquid crystalline behavior in spite of having only a single side chain.
61 herein report on a beta-Li2IrO3 phase which, in spite of having the Ir arranged in a tridimensional (
62                                              In spite of high complete remission rates in Acute Myelo
63 latively constant offset throughout the year in spite of high intra-annual fluctuations reaching up t
64                                              In spite of high levels of heavy metal (As, Cd, Tl, Pb)
65                                  This occurs in spite of high surface expression of an inhibitory rec
66  protein regulation matched with CCM status: in spite of high transcript levels in dark, CAH3 protein
67 erative capacity of MYC- or p53-mutant cells in spite of higher genetic damage and a larger cell size
68 ASV did not induce detectable IFN responses, in spite of higher replication levels, and blocked the M
69 M10 mutations associate with longer survival in spite of histological features of aggressive disease.
70 ance of a small population of adherent cells in spite of HMW adhesin specific antibody-mediated immun
71 cally distinct types of dynamical behaviors, in spite of identity of the oscillators.
72 bypass mitotic arrest and embark on anaphase in spite of incorrect chromosome segregation, generating
73                                              In spite of increasing interest in the serpentinization
74                                              In spite of inherently large pulse-to-pulse intensity an
75 networks, and a number of empirical networks in spite of insufficient data measurement contaminated b
76                                              In spite of intensive efforts, the genetic architecture
77 p53, p27 was unable to inhibit DNA synthesis in spite of its abundance, but could inhibit division of
78 TBP(CO2Bu)8 near 810 nm reaches above 500 GM in spite of its completely centrosymmetric structure.
79 ction relationships by folding upon binding, in spite of its disordered, atypically hydrophilic and r
80  rapamycin's antitumor activity in epidermis in spite of its efficient immunosuppressive properties.
81                                              In spite of its familiar phenomenology, the mechanistic
82                                              In spite of its importance for GPI-anchored protein func
83 bolism in gut systems remains poorly studied in spite of its importance for microbial growth and its
84                                              In spite of its importance, its structure and the molecu
85                                              In spite of its lack of enzymatic activity, human OASL p
86                                              In spite of its large availability in natural or shale g
87                                              In spite of its long-standing importance, exquisite cont
88                                              In spite of its low apparent aromaticity the new octaphy
89 ion complex is more photoactive toward cells in spite of its low ligand exchange quantum yield.
90                                              In spite of its microbial production and rich stereochem
91                                              In spite of its overall high expression, here we find th
92                                              In spite of its simplicity, a two-state allosteric model
93                                              In spite of its simplicity, the proposed decision algori
94                                              In spite of its structural similarity to acetylcholine,
95  are barely introgressed by Amerindian genes in spite of known contact and admixture.
96 nglion (STG), exhibit robust neural activity in spite of large (20 degrees C) temperature fluctuation
97 tes in slowing down the magnetic relaxation, in spite of large calculated single-ion quantum tunnelin
98                                              In spite of low BIT value in surface sediment, the recon
99 pion organic solar cells is highly efficient in spite of low bulk charge-carrier mobilities and short
100      In SA, the high rate of LV hypertrophy, in spite of low peripheral resistances and low-to-normal
101 nts may have potential clinical significance in spite of low risk of malignancy.
102                                              In spite of maintenance treatment with immunosuppressive
103            This broad similarity is observed in spite of many loci possessing cell type specific stru
104 ibutes to the stability of odor recognition, in spite of marked sensor instabilities.
105 ain largely unchanged and nucleoids visible, in spite of marked structural changes during chloroplast
106                                              In spite of markedly low tissue levels of iron, the doub
107 f multiparous females that remain uninfected in spite of massive exposure to SIV identify wild AGMs a
108  sialylation of plasma proteins was observed in spite of NANS deficiency.
109                                              In spite of newly emerging therapies and the improved su
110 he levels of HIF1, but not HIF2 target genes in spite of normal levels of hypoxia-inducible transcrip
111 intain their electrical signaling properties in spite of ongoing protein turnover and perturbations t
112 hrombocytopenic hematology/oncology patients in spite of platelet transfusions.
113                                              In spite of poor iron solubility, hydrolysates of Viscoz
114 ng ability of 3 for the MoNA matched spectra in spite of potential risk of false positive annotations
115 n with antigenically distinct sH1N1 isolates in spite of preexisting, cross-reactive, HA-specific ant
116                                              In spite of prominent changes in the myeloid compartment
117                                              In spite of promising early results, the delivery and th
118 through deep sequencing remains challenging, in spite of rapid drops in cost and throughput increases
119                                              In spite of recent advances in the synthesis of hollow m
120                                              In spite of recent advances, the fate of ABA following t
121                                              In spite of recent developments in ozone exposure metric
122                                              In spite of recent progress, there is still a lack of re
123 l mediator of nicotine-induced whole-body IR in spite of reductions in adiposity.
124 ments demonstrated that ASI could bind to GR in spite of relative low affinity.
125 maximal visual acuity of 14.0 cycles/degree, in spite of relatively small eyes.
126       We conclude that most HG-DCIS lesions, in spite of representing a preinvasive stage of tumor pr
127                                              In spite of research on analyzing biological systems, we
128 dies have yielded a surprise by showing that in spite of resisting localization, topological insulato
129 imes of the year while others are ubiquitous in spite of seasonal shifts in environmental variables.
130  stoichiometry have had only limited success in spite of several theoretical predictions.
131 n vivo might transmit a range of frequencies in spite of short-term plasticity is poorly understood.
132                                              In spite of significant activation of circulating CD8(+)
133                                              In spite of significant improvements in measures of memo
134                                              In spite of significant progress in recent years, the at
135                                              In spite of significant remaining uncertainties, these f
136                                              In spite of significant technical advances, genesis and
137 se mice are absent when they lack caspase-2, in spite of similar levels of amyloid beta (Abeta) depos
138                                              In spite of similar peak plasma viral loads between the
139                                              In spite of similarities in structure and function, the
140 mals) depends on shared molecular mechanisms in spite of some differences that emerged during a billi
141 m an apparently quiescent fully formed state in spite of steady background flow and limited mass accr
142 convergent evolution at the nucleotide level in spite of strong similarities in overall phenotypes.
143                             So far, however, in spite of suggestions of increased variability, there
144 across all levels of surgical experience and in spite of technological advances to improve safety.
145                                              In spite of that, only 28% and 44% of the countries repo
146                                              In spite of the additional beta-branched amino acid at t
147                                              In spite of the advancements made in the past 40 years,
148                                              In spite of the advances in the study of the CNV landsca
149                                              In spite of the advances with AIT, safer and more effect
150 st closely approximated SOA from turf grass, in spite of the approximately 5x lower emission rate of
151 plants (alfalfa and M. vulgare) was similar, in spite of the big difference in Hg accumulation in roo
152 otation barrier of 6.5 kcal mol(-1) at 298 K in spite of the bulkier aryl groups.
153 carcely used in foodstuffs and never in wine in spite of the complexity of their spectra and classifi
154                                              In spite of the continuing efforts in the past decade, t
155                                              In spite of the determination of X-ray structures of inc
156                                              In spite of the differences in chemical composition, ant
157                        Our data suggest that in spite of the differences in morphology and compositio
158                                              In spite of the different conservation priorities accord
159  lattice constant of the film did not change in spite of the displacement of equatorial oxygen atoms.
160                                              In spite of the diversity of possible biological forms o
161                                              In spite of the economic and medical importance of filam
162  when it will strike remains an elusive goal in spite of the ever-increasing volume of data collected
163                                              In spite of the excellent safety profile and absorption
164  A-Tg++ mice displayed severe enamel defects in spite of the expression level of transgenes, while th
165 an (LMS) orogenic belt, is accurately imaged in spite of the extreme topographic relief in the LMS re
166                                              In spite of the extreme variability of the volatile prof
167 or why N-debenzoyl-2'-deoxy-PTX is inactive, in spite of the fact that it is essentially a substitute
168  exert further negative effects on the biota in spite of the fact that it will likely persist for cen
169 e had been tested for antimalarial activity, in spite of the fact that kalihinol A is the most potent
170 re often considered to be mutually exclusive in spite of the fact that many cancer and embryonic cell
171 rations has been examined for few organisms, in spite of the fact that synchrony is ubiquitous and of
172                                              In spite of the fact that the nitride group is multiply
173                              Remarkably, and in spite of the fact that the proposed approach does not
174 d proportional to the number of cells added, in spite of the fact that these added cells are extremel
175 s nucleophiles) remains uncharted territory, in spite of the far-reaching impact such reactions would
176 oinduced ET in an Au-TiO2 system is possible in spite of the fast energy relaxation.
177 insects appear to be exclusively monandrous, in spite of the fitness benefits that polyandry could pr
178                                              In spite of the GLA-associated reduction in antigen deli
179 combined with either 2 or 4 equiv of TEU(-), in spite of the greater reactivity of SmI2/4 TEU(-) with
180                                              In spite of the high conservation of the active site res
181                                              In spite of the high degree of amino acid sequence conse
182                                              In spite of the high health burden of genital herpes, th
183 nt parameters like flavonols or anthocyanins in spite of the high heterogeneity of the samples.
184                                              In spite of the high seroprevalence of infection, the ri
185                                              In spite of the huge biodiversity in most ecosystems, a
186                                              In spite of the importance of Mediator, the range of its
187                                              In spite of the important regulatory functions of antise
188                         Our study shows that in spite of the increasing ease for species to spread ou
189                                              In spite of the increasing rates of cataract surgery and
190 in distinguishing wines according to variety in spite of the influences of winemaking techniques and
191 ssociated with reduced cardiovascular events in spite of the intervention's previously documented abi
192 f chiral tertiary centers is enantiospecific in spite of the ionizing strength of the reaction medium
193                                              In spite of the irrelevance of visual information at the
194                                              In spite of the known role of IRF-1 in stimulating type
195 promise for biomarker and pathway discovery, in spite of the lack of successful applications to human
196 d not concordant across genetic backgrounds, in spite of the large and similar phenotypic differences
197                                              In spite of the large number of participants in many mod
198                                              In spite of the largely disordered nature of CBP-ID4, NM
199                                              In spite of the liquid chromatography-mass spectrometry
200 at Cd and As were adsorbed on the sediments, in spite of the lowered pH due to CO2 dissolution in the
201                                              In spite of the many key cellular functions of chloride
202                                        Thus, in spite of the marked variation in mRNA turnover, the t
203                                              In spite of the multinational nature of the study, sampl
204       Remarkably, these results are obtained in spite of the nanofactories being localized in lysosom
205 mation about sound input across the 2 epochs in spite of the neuronal selectivity differences.
206 monly treated by assuming ideal RsC behavior in spite of the nonlinear response of the device, which
207                                              In spite of the numerous tools developed for each compon
208                                              In spite of the ongoing formation of stars in these gala
209                                              In spite of the persistent and massive reduction of LT-H
210                   In contrast to 2 and 3 and in spite of the presence of a 2,6-disubstituted pyridine
211 selective formation of CO (practically 100%) in spite of the presence of a high concentration of phen
212 f how these enzymes can continue to function in spite of the presence of highly oxidizing species are
213  epithelial cells are connected by TNTs, and in spite of the presence of neutralizing antibodies and
214  of restriction genes was lethal to the host in spite of the presence PT modifications.
215 erimental evidence for these nanostructures, in spite of the progress made in theoretical investigati
216 s, statins, and hypoglycemic agents, whereas in spite of the prominent role of oxidative stress in di
217                                              In spite of the rapid developments in various nanosensor
218                                              In spite of the rapid kinetics of virus production, we s
219                                              In spite of the recent identification of the role played
220                                              In spite of the recent increase in endoperoxide antimala
221                                              In spite of the recent interest and advances in linear c
222                                              In spite of the remarkable progress in understanding the
223                                              In spite of the remarkable progress made in the burgeoni
224 trifluoroacetic acid at the carbonyl oxygen, in spite of the reverse order of basicity and nucleophil
225 dapted whilst the response to serine is not, in spite of the same pathway processing the signals pref
226                                              In spite of the samples heterogeneity, a robust, reliabl
227  monomer-to-polymer conversion to be tracked in spite of the shear-thinning behavior, and could be ap
228                                              In spite of the significant mortality and morbidity asso
229                                              In spite of the similar performance, the approaches used
230                                              In spite of the simple body-centered-cubic crystal struc
231                                              In spite of the strong genetic divergence, a small numbe
232                                              In spite of the success of genome-wide association studi
233                                              In spite of the superiorities of TMUPS, its adoption has
234  accurately identify these de novo mutations in spite of the thousands of false-positive errors intro
235                                              In spite of the tripodal linkage, a smooth twist and eff
236 netic cycle shows a high degree of coherence in spite of the turbulent nature of the solar convection
237                                              In spite of the uncertainty in the winter trend, we esti
238                                              In spite of the uniform cancerous nuclear background, as
239 -vis techniques can be used interchangeably (in spite of the very different concentrations used in th
240                                              In spite of the wide application potential of 1,2,4,5-te
241 pectively, who had never sought care for HIV in spite of the widespread availability of free HIV trea
242                                              In spite of their abundance in organisms from all kingdo
243 elamination vibrate in exactly the same mode in spite of their different stiffness and the four-subla
244  adaptive compartments of the immune system, in spite of their divergent developing pathways.
245                                              In spite of their essential role, little is known about
246     These MWCNTs were found to be insulating in spite of their graphitic layered outer structures.
247                                              In spite of their great promise, previously demonstrated
248                        They also reveal that in spite of their high sequence dissimilarity, the two p
249 as these AuNPs emit at different wavelengths in spite of their identical size (ca. 2.5 nm).
250 ependent mechanical properties of nanowires, in spite of their importance for the design, fabrication
251 ntrated solution (FCS) are poorly understood in spite of their importance in fields ranging from biot
252 enicity, less toxicity and easy productivity in spite of their low capacity of gene transfection usin
253             We propose that such approaches, in spite of their many challenges, present great opportu
254 that elicit surprisingly little inflammation in spite of their massive size and persistence.
255                                              In spite of their memory deficit during free reporting,
256                                              In spite of their precipitous encounter with the environ
257 xes, cyclobutadienyl derivatives are unknown in spite of their prevalence in the d-block.
258 er tissues throughout the body ensures that, in spite of their rarity, ILCs are able to regulate immu
259 lications in different research disciplines, in spite of their somewhat "exotic" reputation.
260                                              In spite of their tremendous potential, adoption of the
261                                              In spite of their usefulness and fundamental role in the
262                            We also show that in spite of their very different physiological functions
263 racellular defense mechanisms and/or persist in spite of them.
264 ith significant morbidity and mortality and, in spite of therapeutic advances, remains an enormous pu
265                                              In spite of these attributes, relatively few catalytic e
266                                              In spite of these challenges, the importance and value o
267                                              In spite of these characteristics, its use in preclinica
268                                     However, in spite of these efforts, during the last 3 years (2013
269  to extract and use unconventional heavy oil in spite of these externalities.
270                                              In spite of these functional defects, platelet adhesion
271                                              In spite of these numbers, children and adolescents have
272                                              In spite of these profound alterations, DeltaEGFR livers
273                                              In spite of these promising anticancer effects, the mole
274                                Surprisingly, in spite of these significant differences, only minimal
275                                              In spite of these significant specific responses, the be
276                                              In spite of this difference, we were able to develop a r
277                                              In spite of this event, the Stokes shift dynamics is rul
278                                              In spite of this huge amounts of data, the solutions to
279                                         Yet, in spite of this importance, reliable methods to measure
280                                              In spite of this impressive ability, failures of self-re
281                                              In spite of this memory loss, early experiences influenc
282                                              In spite of this performance potential, though, many use
283                                Surprisingly, in spite of this reduction in muscle pathology, muscle f
284                                              In spite of this robustness, these catalysts readily dec
285                                              In spite of this stochastic response variation, individu
286                                              In spite of this visual anisometropia, monovision has be
287                                              In spite of this, crayfish maintained positive growth ra
288                                              In spite of this, however, there have been no modern hum
289                           LVS infection; but in spite of this, macrophage IKKbeta is also a critical
290                                              In spite of this, mass extinctions are thought to have o
291                                              In spite of this, spectroscopic studies have never captu
292                                              In spite of this, the number and spectrum of transcripts
293 f analytical instruments should be improved; in spite of this, there are several good domestic instru
294 threatening collapse of the cardiac function in spite of treatment with venous-arterial extracorporea
295                                              In spite of tremendous efforts, characterization of thes
296                                              In spite of tremendous promise as a thermal material, re
297                                        Thus, in spite of universal access to electricity, the Baepend
298 that captures significant biological signals in spite of various noise sources such as batch effects
299                                              In spite of widespread interest in rotaxane-based molecu
300  rarely reuse expert knowledge of phylogeny, in spite of years of effort to assemble a great "Tree of

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