ライフサイエンスコーパス: in the absence of

1 alpha enhancers are significantly diminished in the absence of 53BP1.

2 using a PAd3-Pd catalyst that proceeds at rt in the absence of a base or metal mediator.

3 In the absence of a cure, treatment comprises absolute a

4 an algorithm that estimates dd-cfDNA levels in the absence of a donor genotype.

5 In the absence of a formal national clinical registry si

6 nstar when fed a nutritionally complete diet in the absence of a gut microbiota.

7 t they commonly deviate into the septum even in the absence of a muscular VSD.

8 erform electrogenic Na(+)/H(+) exchange even in the absence of a protonatable residue at the Lys-300

9 ast, wounded mSMGs treated with FHs alone or in the absence of a scaffold showed disorganized collage

10 delta-PCNA collides with the slower CMG, and in the absence of a stabilizing Pol delta-CMG interactio

11 In the absence of a surface, FXII-R353A and FXII-T activ

12 RATIONALE: In the absence of a surgical lung biopsy, patients diagn

13 ntaneous fluctuations in hemodynamic signals in the absence of a task or overt stimulation are used t

14 of air pollution and understand variability in the absence of a true gold standard metric.

15 to Rtn4 or phosphoribosylation of ubiquitin in the absence of a ubiquitination target.

16 h both TLR7 and TLR9, which was not utilized in the absence of Ab.

17 e channel activity that can be observed even in the absence of accessory proteins implicated in the f

18 ace during ACE inhibitor use and no swelling in the absence of ACE inhibitor use) were enrolled at Va

19 es that change intake or fat deposition even in the absence of actual food unpredictability.

20 K4 or FSL-1, as well as the TLR4 agonist LPS in the absence of additional ATP.

21 es (antisocial rewarding) deters cooperation in the absence of additional countermeasures.

22 ntrosome number can be chronically increased in the absence of additional genetic defects.

23 In the absence of aFGF+ChABC fewer catecholaminergic axo

24 receptor (NMDAR) channels, and this occurred in the absence of agonists.

25 ntine increased aggression in AHAs, but only in the absence of alcohol.

26 r expression after PNS injury were disrupted in the absence of alphaBC.

27 elease across a wide range of concentrations in the absence of altered caffeine sensitivity as well a

28 Moreover, in the absence of AMPK, cells generate more mechanical s

29 In the absence of amplification methods for proteins, th

30 y of the severity of the exocrine lesion and in the absence of amyloid deposits.

31 rature, while preventing leaky transcription in the absence of an activation signal.

32 ow plants endure Phe accumulating conditions in the absence of an excretion system is currently unkno

33 lant cell wall; however, expression of clr-1 in the absence of an inducer is not sufficient to induce

34 the induction of protective immune responses in the absence of anaphylactic reactions.

35 In the absence of antibiotic-mediated selection, sensiti

36 rferon-gamma (IFNgamma) and granzyme B (GZB) in the absence of antigens, whereas control exosomes der

37 T cell counts and control viral replication in the absence of antiretroviral therapy (ART).

38 plex of an earth-abundant metal (manganese), in the absence of any additives, base, or hydrogen accep

39 ith either i.v. or i.p. cocaine presentation in the absence of any cue.

40 These changes occur in the absence of any detectable tissue inflammation, an

41 H bromides with 2-aminopyridines takes place in the absence of any reagent in a cascade SN2'-6-endo-t

42 on site controls enzyme activity: (i) PFL-AE in the absence of any simple monovalent cations has litt

43 HIV-1 production and viral infectivity even in the absence of APOBEC3.

44 (rR) features of mixed-metal model complexes in the absence of appropriate diiron models.

45 ologous and heterologous O-antigens, whereas in the absence of arabinose, SLT16 (pCZ1) mainly express

46 ng; although Q301E(7.39) degraded chemokines in the absence of arrestin, S103D(2.63) had reduced CXCL

47 exposing oligodendroglial cells is abrogated in the absence of ATG5.

48 and Hill coefficient of each mutant assayed in the absence of ATP were similar to those of wild-type

49 In the absence of Atthog, SMO was stabilized at the cell

50 f Roquin was examined in immune cell subsets in the absence of autoimmune complications.

51 e find that robust courtship memory elicited in the absence of aversive chemical mating cues also is

52 nd BACE1 accumulation in dystrophic neurites in the absence of BACE1 S-palmitoylation in mouse models

53 Demonstrating tumor control in the absence of BCMA, we maintained cytolysis of prima

54 ent collective behavior when in groups, even in the absence of biochemical signaling.

55 horylation events and new C-C bond formation in the absence of biotin has remained a mystery since th

56 enocarcinomas increase bone stromal activity in the absence of bone metastasis.

57 Increased myocardial rupture in the absence of both Cd36 and Mertk underscore the phy

58 nduced DNA lesions cause genomic instability in the absence of Brca2.

59 TLR7 activation by PapMV in the absence of C3 induced higher IFN-alpha production

60 Consistent with experimental data, MD runs in the absence of Ca(2+) and Ax culminated in target bin

61 Measurements of myofibrillar ATPase activity in the absence of Ca(2+) showed a significant increase i

62 In the absence of Ca(2+), S-2288 cleavage by wild-type H

63 In the absence of calcium chelating salts, these concent

64 gelsolin homology domains G3 and G4, which, in the absence of calcium, are compacted but adopt an op

65 tive to control mice, and eventual lethality in the absence of cardiac fibrosis.

66 onor-acceptor complex permits the reactivity in the absence of catalyst.

67 tlement and metamorphosis increased from 11% in the absence of CCRA to 45-69% when CCRA were present,

68 Modeling suggests some CH cases could arise in the absence of CD mutations as a result of neutral dr

69 units that are crucial to maintain stability in the absence of cementing proteins or cross-linking, a

70 Although mitotic cell cycles can take place in the absence of centrosomes, this is an error-prone pr

71 The frequency and persistence of bacteremia in the absence of clinical symptoms was notable, and mar

72 intervention and evaluate putative efficacy in the absence of clinical symptoms.

73 of the promoter region exhibited an increase in the absence of Clp1 activity, thus implicating Clp1 i

74 In the absence of CO (under N2 atmosphere), the reaction

75 e of CO and1-aryl-(1H)-benzo-1,2,3-triazoles in the absence of CO through a common intermediate was p

76 In the absence of coiled-coil formation, the C-terminal

77 same time, significant advances are possible in the absence of complete data and statistical certaint

78 of gemcitabine and capecitabine is preferred in the absence of concerns for toxicity or tolerance; al

79 r Ras or Braf mutations, and hence developed in the absence of constitutive MAPK pathway activation.

80 ne seeking induced by foot-shock stress, but in the absence of continued global elevations in H3K9me2

81 Our results suggest that in the absence of conventional transcription cycles, RBC

82 We also show that, even in the absence of correlations, for Gaussian white noise

83 gnosis are at risk for deficits in IQ and PS in the absence of cranial radiation, regardless of MTX d

84 findings have identified matrix remodelling, in the absence of cytoskeletal tension generation, as a

85 coupling between RE and RG that is amplified in the absence of denaturants.

86 ical secondary structure at room temperature in the absence of denaturants.

87 ffects across current episodes or remission, in the absence of detectable progressive neuropathology.

88 Low levels of CP accumulated in vivo in the absence of detectable TCV subgenomic RNAs, strong

89 an infect kidney transplant epithelial cells in the absence of detectable viremia.

90 r protein reconstitution technology proceeds in the absence of dialysis and/or detergent absorbents,

91 suppressed abundances of rodents and rabbits in the absence of dingoes relaxed a recruitment bottlene

92 face, thus enabling effects on the interface in the absence of direct binding in that location.

93 d that the brain will function optimally and in the absence of disease throughout life.

94 6-12 week old wild-type and transgenic mice in the absence of disease.

95 We report that, in the absence of distal target organs, molecular guidan

96 andensis DNase II is highly active at low pH in the absence of divalent metal ions, similar to eukary

97 In the absence of DNA damage, on the other hand, chromat

98 In the absence of Dna2, MRN together with CtIP mediate a

99 In the absence of dopamine D2/3 receptor occupancy data

100 core recapitulated cue-induced reinstatement in the absence of drug-associated cues.

101 f subcutaneous inguinal white adipose tissue in the absence of Egr1 identifies the molecular signatur

102 We show that in the absence of Eiger, the only known tumor necrosis f

103 Following sodium depletion, and in the absence of either sucrose or salt, we found that

104 e endogenous memory prioritization processes in the absence of emotional input, addressing a fundamen

105 In the absence of endogenous Treg, IVIg failed to confer

106 ndergo spatially patterned self-organisation in the absence of epithelial direction.

107 n-replete status cannot be made at this time in the absence of established cutoffs for iron repletion

108 In the absence of exogenous estradiol, a TD by ACE inter

109 cells can persist and/or proliferate in vivo in the absence of exogenous human cytokines.

110 olated from IL5tg mice, they survive ex vivo in the absence of exogenous pro-survival cytokine suppor

111 ocortex exhibit spontaneous spiking activity in the absence of external stimuli, but the origin and f

112 itionally, polarised T/Bra expression occurs in the absence of extra-embryonic tissues or localised s

113 t tested the effects of SMIT1 co-expression, in the absence of extracellular myo-inositol or other SM

114 In the absence of F-actin, the sperm DNA, centrioles, an

115 A decrease in HK2 levels in the absence of FGF signalling inputs results in decre

116 protein, revealed an enhanced release of TNF in the absence of Fhl2.

117 s, elastic interfacial film formation occurs in the absence of flagella, pili, or certain polysacchar

118 ates the proteolytic cleavage activity, even in the absence of forces or denaturants.

119 the mid-infrared-something that is forbidden in the absence of free electrons.

120 In contrast, in the absence of fucosylation, sialylation did not adve

121 ability to perform complex locomotor actions in the absence of full consciousness.

122 ional-1 to transitional-2-MZ precursor stage in the absence of functional IkappaBNS.

123 tening induces chromosomal instability that, in the absence of functional tumor suppressor genes, can

124 measured plant productivity was much higher in the absence of fungi and arthropods.

125 , or sluggish or sedentary adult life habits in the absence of gamete vectors, appear to be incompati

126 and cultural practices alter CVD risk, even in the absence of genetic changes.

127 ic modifications induced by hatchery rearing in the absence of genetic differentiation between hatche

128 ases of Pi-induced force kinetics that occur in the absence of "give" yield the same information as m

129 c potential to use chitin as a carbon source in the absence of glucose, importing it via the chitin-u

130 s are capable of eliciting action potentials in the absence of glutamatergic currents.

131 In the absence of glutaraldehyde, half-lives ranged from

132 sed to promote a more chondrogenic phenotype in the absence of growth factors, potentially providing

133 .Z-mediated splice defects, indicating that, in the absence of H2A.Z, stalled spliceosomes are disass

134 were highly expressed in oxyR2 mutants even in the absence of H2O2 Further genetic analyses suggest

135 tching was performed between SLK-HCC and SLK in the absence of HCC (SLK-A) groups to reduce confoundi

136 In the absence of HGF, cell trajectories are highly tort

137 strategy was more effective than the others.In the absence of high-quality evidence, low-quality stu

138 te, monitor, and switch goals and strategies in the absence of human intervention.

139 ight-management behaviors (i.e., eating even in the absence of hunger), which were predictive of havi

140 ctivity measured by resting-state fMRI, even in the absence of hypometabolism (measured with PET [(18

141 In the absence of IL-27R myeloid cells become hyperactiv

142 host blood glucose levels for over 370 days in the absence of immunosuppression (excluding the first

143 In contrast, in the absence of increasing aridity, climate warming is

144 ke by the liver spheroids, while the latter, in the absence of insulin, did not consume glucose as ef

145 longed proliferation in explanted wing discs in the absence of insulin, incidentally providing novel

146 ocalization between Rab11A and vRNA segments in the absence of intact MT filaments, we analyzed the t

147 t high-performing circuits can be engineered in the absence of intensive purification and/or extensiv

148 In the absence of interaction with GIPC1, missorting of

149 merous repetitions of the very same stimulus in the absence of interference.

150 cked by the IP3 antagonist, and not observed in the absence of IP3 IP3 potentiation was also blocked

151 e was sortilin independent and occurred even in the absence of its native lumenal domain.

152 2 and BIS1 are repressed by the JAZ proteins in the absence of JA, but de-repressed by the SCF(COI)(1

153 ondensation at heat shock loci is unaffected in the absence of JIL-1 as well as of H2Av and that ther

154 We show that in the absence of KCNE1, S140G, but not V141M, directly

155 As, miR-100 and miR-125b, were overexpressed in the absence of known genetic events linked to cetuxim

156 Conclusion In the absence of known renal failure, neonates receivin

157 on of intermediates that resemble those seen in the absence of LepA.

158 vation of gene expression and proliferation, in the absence of ligand or presence of 4OH-tamoxifen (T

159 open conformations of the SAM-II riboswitch in the absence of ligand.

160 nic retinal pigment epithelium (RPE)/choroid in the absence of light.

161 In the absence of linker contacts, H-NS binding is signi

162 efficient pEtN lipid A substitution is seen in the absence of lipid A glycinylation.

163 The thermodynamic signature of AmtB-GlnK in the absence of lipids indicates conformational dynami

164 ular organism avoid lethal cellular collapse in the absence of liquid water?

165 3 (PFIC3), a rare disease that can be lethal in the absence of liver transplantation.

166 temporal trends in predicted breeding values in the absence of local selection.

167 In the absence of LRAP, PPi inhibition was reversed by t

168 Although rescue of epidermal wound closure in the absence of macrophages promotes blastema accumula

169 ta-globin promoter forced LCR loop formation in the absence of mediator or cohesin occupancy.

170 be offered 6 months of adjuvant chemotherapy in the absence of medical or surgical contraindications.

171 izing mGluR5, but reinstated sucrose seeking in the absence of mGluR2/3 blockade was not affected by

172 In the absence of microbial products, the transcription

173 ns and negative emotions during, rather than in the absence of, migraine or in control subjects, and

174 Yet a model of U(IV) speciation in the absence of mineral formation under field-relevant

175 diaphragm muscle fiber atrophy and weakness in the absence of mitochondrial dysfunction and oxidativ

176 In the absence of mitotic rounding, geometric cues impos

177 L-null mice supporting direct actions of cKL in the absence of mKL.

178 he first EF-P ortholog that retains function in the absence of modification.

179 eg-cell suppression of mast cell activation, in the absence of modulation of T- or B-cell responses.

180 In a warmer climate, ER increases year-round in the absence of moisture stress resulting in net CO2 u

181 d the type 1 Cu(2+) is not reduced by Mn(II) in the absence of molecular oxygen, indicating that subs

182 Receptor activation in the absence of monoamines results from the production

183 In the absence of Mss116, Pet309 is virtually absent, an

184 anule homotypic fusion) was severely reduced in the absence of Munc13-4.

185 In the absence of N-terminally truncated forms, blocking

186 d neuronal development in the Xenopus embryo in the absence of n1-src, while preserving c-src Loss of

187 ptic digestion of SERT-expressing membranes: in the absence of Na(+), the N terminus was rapidly dige

188 d with a very slow reaction at 125 degrees C in the absence of NaBAr(F)4.

189 w that incorporation of SERINC5 into virions in the absence of Nef inhibits the formation of small fu

190 latent virus and low-level viral replication in the absence of neuro-disease.

191 In the absence of neuropathy, a bortezomib-rituximab-bas

192 ERK phosphorylation is significantly reduced in the absence of NOD proteins, but receptor-interacting

193 ell in a pattern recognition task show that, in the absence of noise, leakage of plasticity to adjace

194 In the absence of noise, the spectrum can be fully decod

195 h to model membranes to a larger extent than in the absence of NOM (including those incorporating lip

196 th diarrhea (noro group), and 8 had diarrhea in the absence of norovirus (control group).

197 and p97 associate in the presence of ATP and in the absence of nucleotide, but not in the presence of

198 In the absence of on-the-ground measurements to provide

199 The survival of MRD stem or progenitor cells in the absence of oncogenic kinase signaling, a phenomen

200 c rhesus monkeys that had survived infection in the absence of or after treatment with candidate medi

201 In the absence of osmotic stress, group 1 ACQOS contribu

202 somes, forms an intrinsic dye-permeable pore in the absence of other cellular components.

203 like profile of biomarker abnormalities even in the absence of other hallmarks of the disease such as

204 form similar ER-associated viral structures in the absence of other major virion proteins.

205 why shamanism professionalizes early, often in the absence of other specialization, and (3) how shif

206 sustained production of IgE antibody in vivo in the absence of other T-cell subsets or even when TH2

207 re and fertility were significantly impaired in the absence of ovarian Edn2 expression.

208 Unexpectedly, this occurs in the absence of overt inflammation.

209 opmental myelination and remyelination, even in the absence of overt inflammation.

210 In the absence of oxidative stress, HPbetaCD addition in

211 t required for intrahepatic transplantation; in the absence of oxygen treatment, diabetes was not rev

212 e sensory representation of conspecific cues in the absence of oxytocin signaling.

213 on of reactive oxygen species and cell death in the absence of p53.

214 In the absence of PD-ligands, both TS1 TEM and TN induce

215 TEM induced more severe skin and liver GVHD in the absence of PD-ligands.

216 In the absence of periodicity and the presence of quasic

217 ors failed to support robust HBV replication in the absence of PGC1alpha.

218 NCX inactivation occurs in the absence of phosphatidylinositol 4,5-bisphosphate

219 the hematocrit increased thrombin generation in the absence of platelets; however, this effect was re

220 In the absence of PLST-1, polarization was compromised,

221 he replisome is highly resistant to dilution in the absence of Pol III* in solution.

222 he Deltaarg knockout was incapable of growth in the absence of polyamine supplementation, but the aux

223 like DksA, TraR activates transcription even in the absence of ppGpp.

224 (-)3TC-TP molecule bound to the active site in the absence of PPi, suggests that nucleotide binding

225 by postsynaptic trains of action potentials in the absence of presynaptic stimulation.

226 cause CO2 sensitivity, which can occur even in the absence of productive viral replication.

227 ly to barbed ends, where it slows elongation in the absence of profilin and allows, but does not acce

228 In the absence of progression, patients in arm B continu

229 In the absence of pUL31, CMV fails to reorganize nucleol

230 adhesin protein can regenerate its thioester in the absence of pulling.

231 In addition, garcinol administered in the absence of reconsolidation or at a 6 h delay when

232 Screening for AFC should be performed even in the absence of red flags in patients with HCM older t

233 In the absence of reliable methods to manipulate parasit

234 -risk age window in HTx recipients persisted in the absence of reported nonadherence.

235 mortality hazard in this age range persists in the absence of reported nonadherence.

236 program effectiveness will remain uncertain in the absence of requiring monitoring data be collected

237 In the absence of RhoA, RhoB relocalized to the plasma m

238 any structural or functional impact on RNAP in the absence of RIF.

239 stability, lateral captures predominate even in the absence of rotational diffusion.

240 to limit their accumulation and aggregation in the absence of Rqc1; however, its E3 ubiquitin ligase

241 Additionally, in the absence of S348/S409 phosphorylation LARP6 is seq

242 ion can protect by opsonophagocytic activity in the absence of SBA is not known.

243 istration was predicted to be temporary, and in the absence of scale-up of other interventions, such

244 g, polymerization of Suc in the phloem, even in the absence of segregation, lowers the sugar content

245 o this antibiotic may not be well maintained in the absence of selective pressure.

246 ates and that large, spontaneous CBV changes in the absence of sensory input were driven by volitiona

247 as sufficient to enable dendritic maturation in the absence of sensory input.

248 These effects are observed in the absence of significant sedative side effects.

249 nfirmed that many variants of [PSI+] arising in the absence of Siw14p are cured by restoring normal l

250 In the absence of smoking or hypertension, 0.09% (95% CI

251 Interestingly, in the absence of sodium-dependent Pi transport activity

252 re colonists occupy a patch or locality than in the absence of spatial context dependence.

253 at may be pivotal for function but neglected in the absence of specific cellular microenvironments.

254 ents that trigger myotonic action potentials in the absence of stabilizing ClC-1 current are not full

255 In the absence of stalling, read-through of poly(A) prod

256 In the absence of stenosis, mean MBF under hypercapnia w

257 , degranulation, and phagocytosis are normal in the absence of STIM2, suggesting STIM1 is the dominan

258 dynamics stimulation (tIDS), was higher than in the absence of stimulation (baseline).

259 aradigm, the mechanistic basis for allostery in the absence of structural change remains unclear.

260 st activation, which was shown to occur even in the absence of substrate.

261 ecapitulated in wt mast cells differentiated in the absence of succinate.

262 delivered in the LZ, DZ proliferation occurs in the absence of such signals.

263 ire action potentials in a pacemaker pattern in the absence of synaptic input, the intrinsic properti

264 In the absence of T-bet, IFN-gamma aberrantly induced a

265 anized fluctuations of neural activity, even in the absence of tasks or sensory input.

266 t transdifferentiate into ectopic cartilage; in the absence of tenogenic cells, extrinsic alphaSMA-ex

267 s not form in the context of full-length TER in the absence of TERT, due to formation of a competing

268 icient T cells differentiate into TH17 cells in the absence of TGFbeta signalling in a RORgammat-depe

269 ore prone to adipogenic differentiation even in the absence of the adipogenic inducers.

270 Ubiquitination was increased in the absence of the Bre5-Ubp3 ubiquitin protease compl

271 er conditions where no reaction was observed in the absence of the cage.

272 We found that in the absence of the calyx, IK,L in type I hair cells e

273 To determine if FEO timekeeping persisted in the absence of the food cue, we assessed activity dur

274 TRAPPII is not essential but becomes so in the absence of the gene parcas that encodes the Droso

275 r without oxygen insertion, which accumulate in the absence of the His(64) ligand.

276 in activated CD4(+) T cells were compromised in the absence of the INSR, which was associated with al

277 eased particles with flat envelope curvature in the absence of the matrix (M1) protein layer.

278 nt manner, and both activities are abolished in the absence of the phosphodiestrase YmdB, shown previ

279 as $29.2 million compared with $26.2 million in the absence of the test-an increase of $3.1 million.

280 DNA damage at tDNAs in the absence of these helicases is suppressed by desta

281 In the absence of Thr286 phosphorylation, increasing the

282 s were more likely to be transiting, whereas in the absence of threat, more likely resident.

283 h concentration in a large variety of states in the absence of tissue injury or infection.

284 In the absence of TLR2, TLR4, myeloid differentiation re

285 However, in the absence of TP53, CI leads to the development of s

286 ed residues, using crystal structures solved in the absence of tRNA as a guide.

287 es that HCHO levels would decrease by 20-30% in the absence of U.S. anthropogenic NOx emissions.

288 In the absence of ubiquitin or substrate liposomes, the

289 In the absence of uterine FST, activin B expression and

290 In the absence of veA (DeltaveA), ST biosynthesis is blo

291 In the absence of verbal report, these nociceptive respo

292 fter radical prostatectomy are usually drawn in the absence of visibly recurrent disease.

293 We predicted that in the absence of vision, the "VWFA" is incorporated int

294 In the absence of vivax invasion assays, binding-inhibit

295 In the absence of WAPL and PDS5 proteins, cohesin forms

296 nd defection that maintains cooperation even in the absence of well known mechanisms such as kin inte

297 In the absence of widespread deforestation, exploitation

298 w that RECQL5 is essential for cell survival in the absence of WRN.

299 In the absence of YmfI, accumulation of 5-aminopentanona

300 reimplantation embryos can partially proceed in the absence of zygotic transcription and is a multi-l