ライフサイエンスコーパス: in vitro assay

1 g challenge (expression changes confirmed by in vitro assays).

2 cular architecture on the outcome of a given in vitro assay.

3 ng of the encoded transcription factor in an in vitro assay.

4 showed at least some seeding activity in an in vitro assay.

5 allergen contents can be used as a surrogate in vitro assay.

6 of NTHi by macrophages were evaluated by an in vitro assay.

7 to control the dissemination of virus in an in vitro assay.

8 F motif, had no effect on PP1 activity in an in vitro assay.

9 actor Receptor tyrosine kinase (EGFR-TK), in in-vitro assay.

10 invasion of prostate cancer cell lines in 3D in vitro assays.

11 8a2 and murine ATDC5 cell lines were used in in vitro assays.

12 ibitors and also blocked their activities in in vitro assays.

13 ckdown are known to inhibit cell invasion in in vitro assays.

14 t potent inducers of apoptosis in short-term in vitro assays.

15 volving the use of fluorogenic substrates in in vitro assays.

16 anticancer properties as observed by several in vitro assays.

17 proteasome-related protease activity in the in vitro assays.

18 an exosome inhibitor in vivo and PTEN siRNA in vitro assays.

19 nstrated using eukaryotic cell infection and in vitro assays.

20 herichia coli ligase-deficient strain and by in vitro assays.

21 response in both recombinant and neutrophil in vitro assays.

22 ivities of Limoniastrum amides using various in vitro assays.

23 interoperator differences in performance of in vitro assays.

24 resistance and migration and invasiveness in in vitro assays.

25 as an in vivo model, as well as ex vivo and in vitro assays.

26 r relationship (R2=0.75) between in vivo and in vitro assays.

27 ion by using an APP/PS1 transgenic model and in vitro assays.

28 uglike properties when tested in a number of in vitro assays.

29 and its peptides was characterized by using in vitro assays.

30 ase activity or RNA recognition in different in vitro assays.

31 l activities of VRC01 as measured by several in vitro assays.

32 r effect on spreading using both in vivo and in vitro assays.

33 e astrogliosis in demyelinating areas and in in vitro assays.

34 viability of luminal breast cancer cells in in vitro assays.

35 invasion of prostate cancer cell lines in 3D in vitro assays.

36 l PFOA-related parameters were obtained from in vitro assays.

37 in a variety of human and cynomolgus monkey in vitro assays.

38 and molecular dynamics (MD) simulations, and in vitro assays.

39 ding defects than mutants in clfB in several in vitro assays.

40 the latter showing activating properties in in vitro assays.

41 ation in fluorescence microscopy imaging and in-vitro assays.

42 Additional in vitro assays also demonstrated that psoriatic and con

43 c small interfering RNA (siRNA) delivery, an in vitro assay amenable to high-throughput screening (HT

44 We developed a sensitive in vitro assay and demonstrated that Cas1-Cas2-3 catalyz

45 acids, in agreement with the findings of the in vitro assay and fatty acid feeding test.

46 ntiated the isomerase activity of FipB in an in vitro assay and within the bacteria, as measured by i

47 mode of action in a series of whole cell and in vitro assays and analyzed structural features by nucl

48 emicals established using results from other in vitro assays and because of the lack of high-quality

49 lf-renewal and multipotency, are observed in in vitro assays and cell transplantation experiments; ho

50 Genetic analysis, conformational studies, in vitro assays and ex vivo flow-cytometry were performe

51 This functional mouse model of PMM2-CDG, in vitro assays and identification of the novel gp130 bi

52 organs as spatial objects in living tissues, in vitro assays and in computational models of tissues.

53 We performed a series of in vitro assays and in vivo experiments and analyzed the

54 Using mechanistic in vitro assays and in vivo models of invasive pneumonia

55 ablished and patient-derived GBMs using both in vitro assays and in vivo orthotopic preclinical model

56 inhibits the activities of the serum IgE in in vitro assays and is thought to reduce the symptoms of

57 these factors influence motor motility, and in vitro assays and live cell observations often produce

58 Using in vivo and in vitro assays and microscopy, we show that MciZ, at su

59 By in vitro assays and mutational analysis, we demonstrate

60 etric and infrared spectroscopic analyses of in vitro assays and plant extracts indicate that the fin

61 Using in vitro assays and rescue experiments in autaptic neuro

62 Using in vitro assays and site-directed mutagenesis, we demons

63 t the active site of proteasomes followed by in vitro assays and subsequent optimization, yielding a

64 Using in vitro assays and the mouse model, we compared the inh

65 is capable of attaching ubiquitin to FDH in in vitro assays and the turnover of FDH was increased wh

66 easurement of Der 1 content as the surrogate in vitro assay, and decided that manufacturers can label

67 interaction with double stranded DNA through in vitro assay, and molecular docking study.

68 Here, we combined modeling, in vitro assays, and cellular localization studies to in

69 Molecular genetics, in vitro assays, and expression data suggest that IRX9L,

70 ties of CII using a combination of genetics, in vitro assays, and mutational analysis.

71 opisomers were evaluated through a series of in vitro assays, and shown to have a favorable selectivi

72 RNase BN directly cleaves 6S RNA as shown by in vitro assays, and the 6S RNA:pRNA duplex is an even m

73 cytokines in peritoneal tissue and fluid and in vitro assays applying macrophages and peritoneal fibr

74 Various in vitro assays are available to assess adipocyte differ

75 tools that provide antigenic specificity in in vitro assays are needed to functionally assess the ne

76 ses of antibodies provide protection because in vitro assays are not always predictive of in vivo pro

77 n, the concentrations of labeled proteins in in vitro assays are often kept low compared to their in

78 In vitro assays are widely used to analyze the antioxida

79 A combination of in vitro assays as tools were performed to determine the

80 n, we developed a sensitive and quantitative in vitro assay based on HPLC separation and quantificati

81 We developed an in vitro assay based on solid-supported 1-palmitoyl-2-ol

82 5-LO(-/-) mice exhibited faster healing, in in vitro assays both migration and proliferation of huma

83 RTICBM-74) had similar potencies as 2 in all in vitro assays but showed significantly improved metabo

84 ould expand the range of BMP signaling in an in vitro assay by competition for HSPG-binding.

85 and finger nail samples, this suggests that in vitro assays can reliably mimic the in vivo processes

86 TF binding sites identified via large-scale in vitro assays, chromatin accessibility, evolutionary c

87 In vivo co-expression and in vitro assays combined with nuclear magnetic resonance

88 Further in vitro assays confirmed essential roles of Q89 and Q82

89 In vitro assays confirmed expression regulation via thre

90 In vitro assays confirmed PhCAT2 can transport Phe, and

91 In vitro assays confirmed that enforced Tek expression i

92 In vitro assays confirmed that VIPER-inferred protein ac

93 In vitro assays confirmed the amidotransferase activity

94 In vitro assays confirmed their functionality, and embry

95 nucleatum 23726 and C. albicans SN152 in an in vitro assay could be greatly inhibited by arginine an

96 Our data show that in vitro assays could offer a substitute for fish studie

97 o test data, reference chemical information, in vitro assay data (including Tox21(TM)/ToxCast high-th

98 Models based on in vitro assay data perform better in predicting human t

99 Both in vivo and in vitro assays decreased the ability of CDH23-C to inte

100 In vitro assays demonstrate that Cas9 from Streptococcus

101 In vitro assays demonstrate that Hpm1p has methyltransfe

102 Quantitative in vitro assays demonstrate that motor axons synergistic

103 In vivo and in vitro assays demonstrated that bHLH142 and TDR1 prote

104 In vitro assays demonstrated that DTMUV infected and rep

105 In vitro assays demonstrated that mutant IL-21(Leu49Pro)

106 In addition, yeast transposition and in vitro assays demonstrated that the terminal motif and

107 In vitro assays demonstrated that Tregs cocultured with

108 In vitro assays demonstrated that two such compounds sel

109 Based on in vitro assays demonstrating enhanced extracellular sig

110 RBA (swine model) and bioaccessibility (five in vitro assays), determined whether correlations differ

111 Computational modeling and in vitro assays do not fully replicate the in vivo envir

112 and the fractions were investigated, both in in vitro assays (DPPH radical scavenging activity, reduc

113 minnow (FHM) nuclear PR (nPR), to develop an in vitro assay for FHM nPR transactivation, and to scree

114 piezoelectric biosensor as a cost-effective in vitro assay for the early detection, monitoring or tr

115 s study, we address this issue using a novel in vitro assay for the motility of localising Drosophila

116 We tested combinations in an in vitro assay for the viability of a renal cell adenoca

117 We also established an in vitro assay for TIKI2 protease activity using FRET pe

118 Sophisticated in vitro assays for comprehensive prediction of in vivo

119 gion were used to explore the application of in vitro assays for mutagenicity (Salmonella mutation as

120 We relate these computational predictions to in vitro assays for specificity in which cognate viral R

121 tivity and potent inhibition of HDAC3-NCoR2, in vitro assays for the inhibition of HDAC1, HDAC2, and

122 In vitro assays further confirmed that histamine inhibit

123 In vitro assays further showed that this intron function

124 In vitro assays have demonstrated an intimate associatio

125 In the in vitro assays, HF5 and CD6 inhibited virus spread and

126 0 pathway clients have been identified using in vitro assays, however, the relevance of the TRC40 pat

127 approaches (i.e., in vivo visualization and in vitro assay), HRMAS NMR identified robust and dose-de

128 In in vitro assays human monocyte-derived dendritic cells a

129 proteome profiling of the mutant followed by in vitro assays identified the transcription factor APET

130 ar endothelial cells and, in a wound-healing in vitro assay, impaired cell motility and cytokinesis.

131 nst A. fumigatus infections, we developed an in vitro assay in which the interactions between human n

132 upstream of a luciferase reporter system for in vitro assays in HEK293 and U2OS cells.

133 mGluR2 function by AZD8529 using functional in vitro assays in membranes prepared from a cell line e

134 Using in vitro assays in transfected cells, we demonstrated th

135 The utility of in vitro assays in water quality monitoring was evident

136 We developed an in vitro assay, in which primary mouse mammary epithelia

137 Through in vitro assays, in silico docking and bioinformatics, A

138 In vivo and in vitro assays included RNA sequencing, quantitative po

139 y this compound was confirmed in an array of in vitro assays, including enzymatic tests and cell-base

140 ations of miR-204 targeting capabilities via in vitro assays, including transcriptome analysis.

141 In vitro assays indicate that CDCP1 mediates formation a

142 In-vitro assays indicate that this bio-nanocomposite is

143 In vitro assays indicated blockage of (11)C-sarcosine up

144 Additional in vitro assays indicated that 13 induces cell death wit

145 Further analysis with in vitro assays indicated that depleting PIPKIgamma inhi

146 A combination of in vivo and in vitro assays indicates that LtnA1 and LtnA2 can induc

147 The panel of in vitro assays interrogated multiple end points related

148 A reliable in vitro assay is essential to dissect oligodendrocyte a

149 active AFB1 is low in cost and combined with in vitro assay, is quantitative.

150 noma cells, suggesting that more traditional in vitro assays may not capture in vivo events.

151 In vitro assays (mixed lymphocyte reaction and ELISPOT)

152 ected knockout experiments, combined with an in vitro assay of pathway components, has elucidated for

153 In vitro assay of TcpP oxidation by VcDsbA showed that V

154 Furthermore, in vitro assays of acyltransferases in microsomal fracti

155 This correlation was further confirmed by in vitro assays of C2C12 cells with NO66 overexpression.

156 In vitro assays of cell adhesion, proliferation, and apo

157 of Zt6 protein on functional ribosomes, and in vitro assays of cells treated with recombinant Zt6 de

158 We verified the compounds by in vitro assays of clonogenic survival, proliferation, a

159 In vitro assays of complement function identified a sing

160 The in vitro assays of free antifungal agents were performed

161 Using in vitro assays of interferon gamma production (enzyme-l

162 spectively probed through the following: (i) in vitro assays of specific DNA binding and protein stab

163 An in vitro assay on macrophage cell lysates showed complet

164 Traditionally, ER expression is assessed by in vitro assays on biopsied tumor tissue.

165 Using in vitro assays on differentiating adult NSCs, we identi

166 In vitro assays on frozen-thawed leaf sections revealed

167 ed for the sesquiterpenic compounds by these in vitro assays opens a perspective for their promising

168 ot display all the phenotypes predicted from in vitro assays or analyses of mice lacking predicted re

169 sors targeted to small molecule analytes for in vitro assays or molecular imaging in vivo.

170 oth transgenic and knock-out mice along with in vitro assays, our data show that Zhx2 binds Mup promo

171 In vitro assays performed on spleen and lymph node secti

172 Target-specific, mechanism-oriented in vitro assays post a promising alternative to traditio

173 We found that in vitro assays predicted in vivo properties of TRIC and

174 Most of the fast in vitro assays proposed to determine the antioxidant ca

175 is question, we exploited a prion conversion in vitro assay, protein misfolding cyclic amplification

176 In vitro assays proved that recombinant VHR directly dep

177 This novel in vitro assay provides a realistic human cell based mod

178 ncorporating microparticles into tissues for in vitro assays remains a challenge.

179 We developed an in vitro assay requiring only isolated LDs, Coenzyme A,

180 ts the fibrillation of alpha-synuclein in an in vitro assay; residues 158-180, containing a largely c

181 determined by chromatographic techniques and in vitro assays, respectively.

182 invasion of prostate cancer cell lines in 3D in vitro assays, respectively.

183 In vitro assay results determined that L-ASu inhibited s

184 In vitro assays reveal that PA specifically and directly

185 In vitro assay revealed that the RNA nanoparticles speci

186 In vitro assays revealed an inhibitory activity of couma

187 h increased cell passaging, and a battery of in vitro assays revealed no significant differences in t

188 Moreover, in vitro assays revealed that apurinic/apyrimidinic nucl

189 In vitro assays revealed that CLASP directly functions t

190 In vitro assays revealed that DGKalphaDelta10 translocat

191 lowing the synthesis of the best candidates, in vitro assays revealed that one member of this chemica

192 In vitro assays revealed that the defective response in

193 In vitro assays show differential tubulin-binding affini

194 In vitro assays show that CCD2 cleaves sequentially the

195 proteome induced by ablation of pATOM36 and in vitro assays show that pATOM36 is required for the as

196 Our in vitro assays show that they act as suppressors of the

197 Various results, including in vitro assays, show that the FG/GLFG region of Nup98 b

198 In vitro assay showed that medicarpin inhibited uredinio

199 In vitro assay showed that miR-93 reduced RyR2-3'-untran

200 An in vitro assay showed that the region I, region II, and

201 In vitro assays showed binding and rapid internalization

202 In vivo and in vitro assays showed that ClpT1 and ClpT2 can independ

203 The results of in vivo and in vitro assays showed that histamine deficiency promote

204 In vitro assays showed that IFIH1 effectively restricts

205 Functional in vitro assays showed that second-trimester human decid

206 luciferase constructs/replicons, in vivo and in vitro assays showed that the 5' and YSS-containing 3'

207 In vitro assays showed that the mutations cause loss of

208 In vitro assays showed Zn-dependent proteolytic activity

209 The aim of this study was to use in vitro assays specific to reproductive and CYP1A mecha

210 oil was assessed by employing two different in vitro assays such as DPPH, ABTS(+) radical scavenging

211 method are correlated well with conventional in vitro assays such as flow cytometry, cell viability a

212 In vitro assays suggested that CD137 deficiency had a li

213 hed a mechanistic investigation using modern in vitro assays/techniques in order to investigate the h

214 sciences, as well as prevascularization and in vitro assay technologies make the first clinical appl

215 e have developed a fast, reliable and robust in vitro assay, termed QIAD, to quantify the effect of a

216 Here, we present the first in vitro assay that accurately recapitulates PORCN-media

217 Here we report a reliable in vitro assay that allows us to quantify the electrogen

218 We used an in vitro assay that models the initial step of ovarian c

219 y AT3G11470) was directly demonstrated in an in vitro assay that phosphopantetheinylated mature Arabi

220 Here, we describe an in vitro assay that quantitatively measures the assembly

221 ne to favor trans pairing, we established an in vitro assay that recapitulates GRASP-dependent membra

222 sive capacity in MSCs, we developed a robust in vitro assay that uses principal-component analysis to

223 e Quaking-Induced Conversion (RT-QuIC) is an in vitro assay that, for the first time, specifically di

224 g strains of the virus are guided in part by in vitro assays that determine the ability of vaccine-el

225 This article reviews in vitro assays that have been used to model mucosal cel

226 bility and for evaluating the performance of in vitro assays that measure estrogenic activity.

227 er, the field has suffered from a paucity of in vitro assays that reproducibly measure the anti-paras

228 change activity of Sos routinely observed in in vitro assays that use fluorescently-labelled analogs

229 spermine, a porin inhibitor, although in an in vitro assay, the influence of spermine on the activit

230 A specific approach combining a classical in vitro assay, the mixed lymphocyte reaction, with deep

231 Using in vitro assays, the degradation of purified His6-Epsilo

232 ive interface and abolish Pcdh19 adhesion in in vitro assays, thus revealing the biochemical basis of

233 In this study, we developed a novel in vitro assay to assess whether human NK cell subsets h

234 We used a simple fluorometric in vitro assay to determine clotting activity in platele

235 axis with demonstrated MC involvement and an in vitro assay to evaluate the effect of DS on MCs.

236 drome, we developed a zebrafish model and an in vitro assay to measure ATPase activity.

237 We have established a visual in vitro assay to measure kinetics and investigate requi

238 alizing activity, supporting the use of this in vitro assay to predict the in vivo efficacy of future

239 We developed a novel in vitro assay to quantify the number of merozoites rele

240 es to 5 PvDBP variants and used a functional in vitro assay to quantify their binding-inhibitory acti

241 Here we develop an in vitro assay to quantitatively measure the contributio

242 Here we use a rapid in vitro assay to show that infectious doses of CWD prio

243 We developed an in vitro assay to understand the role of the ER-stress-m

244 We conducted in vitro assays to assess Abeta42 aggregation and glial

245 out mice, adoptive transfer experiments, and in vitro assays to identify mechanisms underlying persis

246 To evaluate the capabilities of in vitro assays to predict arsenic (As) relative bioavai

247 The capacity of in vitro assays to predict As RBA was demonstrated by th

248 uantitative single-cell and population-level in vitro assays to quantify the endogenous pathway dynam

249 stained lung tumors for MMP19, and performed in vitro assays to test the effects of MMP19 in NSCLC ce

250 rapeutic molecule was evaluated by combining in vitro assays, to test the antitumoral potential on le

251 The combination of a well-established avian in vitro assay, two well-characterized biochemical assay

252 We used an in vitro assay under hypoxic condition to observe an inc

253 Using a leukocyte adhesion in vitro assay under shear forces mimicking blood flow,

254 demonstrate an important correlation between in vitro assays used to evaluate the therapeutic potenti

255 select model parameters can be obtained from in vitro assays using either quantitative (direct estima

256 Through in vitro assays using engineered antigen-presenting cell

257 ISC-hpNSC population, we conducted sensitive in vitro assays using flow cytometry and qRT-PCR analyse

258 In vitro assays using human monocytes confirmed neutral

259 Novel 96-well in vitro assays using neonatal human monocyte-derived DC

260 In vitro assays using rabbit and sheep erythrocytes demo

261 Though in vitro assays using synthetic motor complexes have gen

262 nnels separated by the porous ECM makes this in vitro assay versatile and suitable for a variety of a

263 An in vitro assay was established to measure the associatio

264 By an in vitro assay we demonstrate how three nanobodies atten

265 Using a visual in vitro assay we previously showed that efficient prote

266 By an in vitro assay, we demonstrated that altered RNase H1 ha

267 lets from all patients, and by using a novel in vitro assay, we found that the nucleotide exchange ac

268 n filaments in vivo; in the crossed-filament in vitro assay, we found that Tm2-actin abolishes Myo1c-

269 Using an in vitro assay, we show that these CTFs indeed originate

270 Using a functional in vitro assay, we showed that TbGnTI transfers UDP-GlcN

271 Using in vitro assays, we demonstrate that Nun cross-links RNA

272 ing quantitative fluorescence microscopy and in vitro assays, we demonstrate that Skb1-Slf1 nodes are

273 of mouse population genetics and functional in vitro assays, we describe here a regulatory circuit i

274 Using in vitro assays, we find that snf-10 mutant sperm show a

275 In controlled in vitro assays, we found that intracellular plutonium u

276 rough rational design and optimization using in vitro assays, we have assembled the first DNA "nanosu

277 Using cell-free in vitro assays, we show that chromatin from isolated nu

278 g an in vivo mouse model combined with human in vitro assays, we show that the level of serum FH corr

279 Using parallel cellular and in vitro assays, we show that the Nephrin intracellular

280 Potent analogues identified in the in vitro assay were validated and found to exhibit impro

281 erum after pasta intake or pasta extracts by in vitro assays were considered, thus strengthening effe

282 putational chemistry, organic synthesis, and in vitro assays were employed to develop potent and sele

283 tions of MK+R5020 treatment on angiogenesis, in vitro assays were performed and combinatorial MK+R502

284 In vitro assays were performed to assess the neutralizin

285 In vitro assays were performed to measure efflux of [(3)

286 In vitro assays were performed with minigene constructs

287 ments, relying heavily on in silico methods; in vitro assays were scarcely used.

288 The results from the in vitro assays were used to create an ER Interaction Sc

289 bolically degraded, using a model microsomal in vitro assay (Wistar-Han rats liver microsomes), and w

290 In vitro assay with the sonicated cells of the recombina

291 Using in vitro assays with an archaeal DsrAB, supported with g

292 Using in vitro assays with breast cancer cells, we have confir

293 Furthermore, in vitro assays with crude cell lysate from PCE grown ce

294 involved in the metabolism of vemurafenib in in vitro assays with human liver microsomes.

295 sted for their antiangiogenic activity using in vitro assays with human umbilical vein endothelial ce

296 In vitro assays with primary or bone marrow-derived eosi

297 ncy and specificity of TDG sumoylation using in vitro assays with purified E1 and E2 enzymes, finding

298 fold more efficiently than ceramide based on in vitro assays with substrate preference deoxycholic ac

299 Using in vitro assays with transfected cells and in ex vivo ex

300 e a better understanding in the selection of in vitro assays, with emphasis placed on some common ass