ライフサイエンスコーパス: inactivate

1 counting and subsequently choosing the X to 'inactivate'.

2 ording to the last vaccine type (live and/or inactivated).

3 ow clefts, mutant channels were incompletely inactivated.

4 ludge and sludge where the protozoa had been inactivated.

5 appens in the SC when the FEF is temporarily inactivated.

6 reas genes of metazoan origin were primarily inactivated.

7 tood, little is known about how Igo/Ensa are inactivated.

8 e not nearly as catastrophic as when Mps1 is inactivated.

9 disrupted when the medial frontal cortex is inactivated.

10 s in which endogenous Piezo1 was CRISPR/Cas9 inactivated.

11 esults from mutations in leucine-rich glioma-inactivated 1 (LGI1), a soluble glycoprotein secreted by

12 ction mutations in LGI4 (leucine-rich glioma-inactivated 4).

13 Using CRISPR/Cas9 to genetically inactivate a TWIST2 orthologue, we suppressed the effect

14 four seminal studies that microstimulated or inactivated a key attention-related midbrain structure,

15 In S. enterica, 2AA inactivates a number of pyridoxal 5'-phosephate(PLP)-dep

16 k1) by impeding phosphorylation of, and thus inactivating, a negative regulator of Ulk1, mechanistic

17 tibiotic binding resins may not sufficiently inactivate achievable concentrations of meropenem, cefto

18 We found different adenosine kinase-inactivating (ADK-inactivating) alterations in all resis

19 Exchange of activating ATP to inactivating ADP triggers short helical segments in the

20 When inactivated along with ExoI in Escherichia coli, or Sae2

21 different adenosine kinase-inactivating (ADK-inactivating) alterations in all resistant clones and de

22 osolic AMT1 C terminus, which allosterically inactivates AMT1 trimers.

23 Binding of inactivated and fluorescently labeled Sin Nombre virus (

24 While rabies vaccines are inactivated and thus have an excellent safety profile an

25 re we show that, although the MKP DUSP5 both inactivates and anchors ERK in the nucleus, it paradoxic

26 ion from the lysogenic to lytic state, CI is inactivated, and the two lytic promoters are de-represse

27 in levels treated with an alpha2-antiplasmin-inactivating antibody (P<0.0001).

28 iny neurons but that dopamine acting via PKA inactivates ARPP-16 leading to selective potentiation of

29 ned the full binding affinity to Im7 but was inactivated as a DNase.

30 Vaccination in pregnancy with a monovalent inactivated AS03-adjuvanted split virion influenza A(H1N

31 Then, we inactivated Ascaris eggs through exposure to these carbo

32 hat carboxylic acids at these concentrations inactivated Ascaris eggs when the pH was below the pKa f

33 The crystal structure of this inactivated assembly provides first insight into the bin

34 Thus, precisely how these mutations inactivate BAP1 is unknown.

35 rigenesis was similar whether p16(INK4a) was inactivated before or after exposure to IR.

36 sm by which AMPylation serves as a switch to inactivate BiP, limiting its interactions with substrate

37 By temporarily inactivating Bop1 function, we further demonstrate selec

38 We further present that GAS inactivates both COX-1 and COX-2 equally.

39 Inactivating BRAF mutants in lung predominate over the a

40 Moreover, inactivating BRAF mutations have also been identified in

41 Nitric oxide (NO) is inactivated by cell-free hemoglobin in a dioxygenation r

42 tile ring constriction and thus specifically inactivated by CYK-4 at the division plane.

43 Our results also suggest that virus inactivated by LJ001 induces an immune response, showing

44 ation of NAD(P)H, is upregulated when p16 is inactivated by looking at gene expression profiling stud

45 MTs) in Arabidopsis thaliana are efficiently inactivated by phosphorylation to avoid toxic accumulati

46 hage-encoded anti-CRISPR proteins (Acrs) can inactivate Cas9, providing an efficient off switch for C

47 onic peripheral CB1R blockade or genetically inactivating CB1Rs in the RPTCs ameliorated diabetes-ind

48 nt and functioning in vivo, we concomitantly inactivated CD4 and CD8 genes in mice with intact MHC cl

49 Here, we describe a mouse model in which we inactivated Cic by selectively disabling its DNA-binding

50 trol channel gating via stability of a novel inactivated closed state.

51 h caspase recruitment domain (ARC) binds and inactivates components of the intrinsic and extrinsic ap

52 structures allow completion of a closed-open-inactivated conformational cycle in a single voltage-gat

53 the existence of a glucose-PKA pathway that inactivates conserved zinc finger stress-resistance tran

54 Light inactivates COP1/SPA, in part by excluding COP1 from the

55 1beta-hydroxysteroid dehydrogenase type 2 to inactivate cortisol before it reaches the fetus, leading

56 hydrogenase-2 (11beta-HSD2), which otherwise inactivates cortisol, sustaining tumor cortisol concentr

57 that MLN4924 blocks Cullins neddylation and inactivates CRLs and, in turn, triggers cell-cycle arres

58 the enzyme that otherwise rapidly deaminates/inactivates decitabine, severely limiting its half-life,

59 not neuroblasts, express high levels of a T3-inactivating deiodinase, Dio3.

60 enase (15-Pgdh) activity, which oxidizes and inactivates Delta(12)-PGJ2 and 15d-PGJ2 In contrast, tre

61 vercome this limitation, we developed a self-inactivating DeltaG-rabies virus (SiR) that transcriptio

62 The development of drugs that can inactivate disease-causing cells (e.g. cancer cells or p

63 DnaA and stimulates the hydrolysis of ATP to inactivate DnaA.

64 Opioid stimulation of JNK also inactivates dopamine D2 receptors in a PRDX6-dependent m

65 mistry, against inactivation and rescues MCM inactivated during catalytic turnover by using the GTP-b

66 To study the role of these six BDs, we inactivated each of the six BDs of PBRM1 and re-expresse

67 However, 0.1% detergent treatment did not inactivate EBOV in blood samples from infected NHPs.

68 mples with 0.1% SDS or Triton X-100 does not inactivate EBOV.

69 ained from uninfected donors and spiked with inactivated EBOV.

70 ever, the channels are more sensitive to the inactivating effects of divalent cations, thus, in the p

71 ve, but it is not known how K-Ras activation inactivates EGFR, leading to resistance of cancer cells

72 RPE cell-specific Cre recombinase drivers to inactivate either Dicer1 or DiGeorge syndrome critical r

73 Mammalian systems inactivate endobiotic and xenobiotic compounds by linkin

74 n oncogenic transcription factors might also inactivate endogenous tumour suppressors.

75 ng enzyme CYP27B1 (produces 1,25(OH)2D3) and inactivating enzyme CYP24A1 (produces 24R,25(OH)2D3).

76 CYP24A1, the primary inactivating enzyme for vitamin D, is often overexpresse

77 al expression changes in the thyroid hormone-inactivating enzyme, deiodinase-III (Dio3) and insulin-l

78 Dual specificity phosphatases (DUSPs) inactivate ERK 1/2 through dephosphorylation and can thu

79 When RADX is inactivated, excessive RAD51 activity slows replication

80 ex that produces thrombin by proteolytically inactivating factor Va.

81 normoglycemia through ferritin's capacity to inactivate Fe(2+) ions that otherwise induce free radica

82 reviously immunized with a nonlive, formalin-inactivated (FI)-RSV vaccine has been associated with se

83 of principle, we were able to simultaneously inactivate five tumor suppressor genes (TP53, PTEN, APC,

84 he sequential inoculation of three different inactivated FMDV serotypes (O, A, and Asia1 serotypes) a

85 conclusion, the staphylococcal protease SspB inactivates galectin-3, abrogating its stimulation of ox

86 phic mutations affecting the ARL13b G-domain inactivate GEF activity and lead to Joubert syndrome (JS

87 ranscription and protein expression from the inactivated gene and the recovered organisms also expres

88 at CRISPR-dependent base editing efficiently inactivates genes by precisely converting four codons (C

89 insulin signaling to phosphorylate and thus inactivate GSK3beta, resulting in increased protein synt

90 ted that MT2 exerts its inhibitory effect by inactivating HJV.

91 esign and operational practices necessary to inactivate hNoVs.

92 n N-terminal glucosyltransferase domain that inactivates host GTPases.

93 hole-inactivated-virus vaccine (formaldehyde-inactivated HSV-2 [FI-HSV-2]).

94 l molecule screen to identify compounds that inactivate human HSC myofibroblasts through the quantifi

95 icial DNA and RNA both in buffer and in heat-inactivated human blood serum.

96 a major tumor suppressor that is mutated and inactivated in 50% of all human cancers.

97 S. bayanus cells were completely inactivated in 10 passes without temperature control (co

98 PPO was completely inactivated in 20min at 85 degrees C, however, after 30m

99 d a mouse line in which Pax6 was selectively inactivated in beta cells by crossing animals with floxe

100 studies identify ADIPOR1 signaling, which is inactivated in both obesity and human cancers, as a key

101 (foxl/flox) (cKO) mice, in which Fam20C was inactivated in cells expressing Type I collagen.

102 The STAG2 gene encoding SA2 is often inactivated in human cancer, but not in in a manner asso

103 that lung-specific TFs become preferentially inactivated in lung cancer and precursor lung cancer les

104 g a major impact in neuronal morphology when inactivated in mice.

105 e only gene that was recurrently somatically inactivated in multiple tumors.

106 rotein p53, the "guardian of the genome", is inactivated in nearly all cancer types by mutations in t

107 Liver kinase B1 (LKB1) is mutationally inactivated in Peutz-Jeghers syndrome and in a variety o

108 of the products of a PKS mutant specifically inactivated in the dehydratase domain of extension-modul

109 enerated mice in which Gata6 is specifically inactivated in the pancreas.

110 nsgenic mice in which Tcf7l2 was selectively inactivated in their pancreatic pericytes exhibited impa

111 ne of these core target genes are frequently inactivated in tumors expressing wild-type TP53.

112 In this study, by inactivating in mice the genes encoding both factors in

113 imate the effectiveness of current and prior inactivated influenza A(H1N1)pdm09 vaccination from infl

114 n 2011 and 2012 on the efficacy of trivalent inactivated influenza vaccine (IIV) during pregnancy wer

115 th a standard-dose, egg-grown, quadrivalent, inactivated influenza vaccine (IIV4) during the A/H3N2-p

116 coadministered with a quadrivalent seasonal inactivated influenza vaccine (IIV4) was investigated in

117 to receive seasonally recommended trivalent inactivated influenza vaccine or saline placebo in block

118 to receive vaccine or placebo (all received inactivated influenza vaccine).

119 enuated influenza vaccine, 11 (7 cRCTs) used inactivated influenza vaccine, and 5 (1 cRCT) compared b

120 not be used in 2016-17 and to switch to the inactivated influenza vaccine.

121 ances otherwise compromised Ab production to inactivated influenza vaccine.

122 To date, only inactivated influenza vaccines (IIVs) are available to p

123 Inactivated influenza vaccines confer protection by indu

124 In summary, inactivated influenza virus delivered through PLGA-NPs r

125 poly (I:C) was coated on a microneedle with inactivated influenza virus, and then immunized into BAL

126 rs and describe the genetic aberrations that inactivate its expression.

127 The mutation in CLPX inactivates its ATPase activity, resulting in coassembly

128 CAR inactivates its constitutive activity by phosphorylation

129 PTPN13 is cleaved by calpain-2, which inactivates its phosphatase activity and generates stabl

130 ite causes AR to accumulate on chromatin and inactivates its transcriptional function as a consequenc

131 JA levels, demonstrating that all four JOXs inactivate JA in plants.

132 en who had received a JE-CV booster after an inactivated JE vaccine primary immunization.

133 Dysfunction of the fast-inactivating Kv3.4 potassium current in dorsal root gang

134 ent of children with a state-of-the-art self-inactivating lentiviral vector (LV-w1.6 WASp) has result

135 vation, the master regulator of meiosis Mei2 inactivates Mmi1, thereby allowing expression of the mei

136 tion of mechanically activated currents that inactivate more slowly than wild type, indicating that i

137 ivated at more hyperpolarized potentials and inactivated more slowly than it is in postnatal and adul

138 ted goal choices and tracked changing rules; inactivating mPFC attenuated CA1 prospective coding.

139 n mice, which was associated with failure to inactivate mTORC1 during fasting.

140 s mTORC2-robosome association, both of which inactivate mTORC2 leading to inhibition of Akt phosphory

141 describe the first substrate complex in the inactivated mutant form of PcCgkA at 1.7 A resolution.

142 by alternative splicing, are the targets of inactivating mutation events in breast, liver, and head

143 nction of UL12, we introduced an exonuclease-inactivating mutation into the viral genome.

144 PrxII deletion in mice with inactivating mutation of adenomatous polyposis coli (APC

145 uently altered genes, mutated exclusively by inactivating mutation, was LYST (10%), which may represe

146 iers of inherited heterozygous germline BAP1-inactivating mutations (BAP1(+/-)) developed one and oft

147 families) were documented to share biallelic inactivating mutations affecting the NKX6-2 homeobox dom

148 l carcinoma (LUSC) that is enriched for both inactivating mutations and deletions in NSD1.

149 adenocarcinoma in vivo, indicating that BRAF-inactivating mutations are initiating events in lung onc

150 CRC cells containing FBW7-inactivating mutations are insensitive to clinically use

151 Because inactivating mutations in ClC-Kb/K2 cause Bartter syndro

152 Inactivating mutations in Eda or Edar cause hypohidrotic

153 ant tumor-suppressor gene syndrome caused by inactivating mutations in either TSC1 or TSC2, and the T

154 CREBBP is targeted by inactivating mutations in follicular lymphoma (FL) and d

155 n be assigned to molecular subtypes based on inactivating mutations in hepatocyte nuclear factor 1A,

156 a connective tissue disease associated with inactivating mutations in lysyl hydroxylase 2 (LH2/PLOD2

157 lycystic kidney disease (ADPKD) is caused by inactivating mutations in PKD1 (85%) or PKD2 (15%).

158 Recently, we described that homozygosity for inactivating mutations in SMIM1 defines the rare Vel-neg

159 zation disorders, is caused in most cases by inactivating mutations in the ABCC6 gene.

160 Inactivating mutations in the Armadillo repeat-containin

161 apreomycin sensitivity and identification of inactivating mutations in the corresponding Mtb gene tly

162 Inactivating mutations in the insulin receptor results i

163 ibroblast growth factor (FGF) receptor 3 and inactivating mutations in the NPR2 guanylyl cyclase both

164 atemia (XLH) is a skeletal disease caused by inactivating mutations in the PHEX gene.

165 Inactivating mutations in the thyroid hormone (TH) trans

166 Inactivating mutations in the transcriptional repression

167 abnormalities exhibited by patients bearing inactivating mutations in the Wiskott-Aldrich syndrome p

168 Heterozygous Gsalpha-inactivating mutations lead to obesity in Albright hered

169 of ISG15 described in mice, humans born with inactivating mutations of ISG15 do not present with any

170 Colon cancers frequently bear inactivating mutations of the adenomatous polyposis coli

171 Here we report hemizygous or homozygous inactivating mutations of the chromosome 14q MAX gene in

172 el (LV) disorder that is caused by inherited inactivating mutations of the RASA1 gene, which encodes

173 Here, we used CRISPR/Cas9 to make inactivating mutations to the NLS on the Il1a gene.

174 ut obvious oncogenic function including BRAF-inactivating mutations.

175 f dC to dU, leading to accumulation of virus-inactivating mutations.

176 r VHL suppression in tumors that do not have inactivating mutations.

177 to treat the NSCLCs harbouring SMARCA4/BRG1-inactivating mutations.

178 Here, human Msh3 was mutated to selectively inactivate MutSbeta.

179 after further digestion, as the irreversible inactivated myrosinase under gastric conditions caused n

180 Piezo1 is responsible for flow-sensitive non-inactivating non-selective cationic channels which depol

181 n Ser(389) mediated by p38 MAPK specifically inactivates nuclear GSK3beta in the cortex and hippocamp

182 Discovering new ways to inactivate pathogens in human waste is critical for the

183 phatases other than MLCP dephosphorylate and inactivate pCPI-17 to restore MLCP activity.

184 n response to HSV and HIV, thus functionally inactivating pDC.

185 This enzyme is able to activate/inactivate peptide hormones and could be involved in a c

186 Pseudomonas syringae effector HopAI known to inactivate plant MAP kinases in M. oryzae.

187 ter PNG activation GNU is destabilized, thus inactivating PNG.

188 nding protein) is inserted into functionally-inactivated point mutants of two target proteins (staphy

189 ndomly assigned to receive tOPV (n = 315) or inactivated polio vaccine (IPV) (n = 299) at 39 weeks.

190 Kano State, Nigeria, introduced inactivated polio vaccine (IPV) into its routine immuniz

191 cine (OPV) only introduce at least 1 dose of Inactivated Polio Vaccine (IPV) into routine immunizatio

192 d for the introduction of at least 1 dose of inactivated polio vaccine (IPV) into the routine immuniz

193 virus-containing vaccine and introduction of inactivated polio vaccine in routine immunization to mit

194 in storage and transportation capacity after inactivated polio vaccine introduction, but temperature

195 ses to booster doses of acellular pertussis, inactivated polio, and diphtheria vaccines at 12 to 24 m

196 A fractional dose of inactivated poliovirus vaccine (fIPV) administered by th

197 Fractional-dose administration of inactivated poliovirus vaccine (fIPV) could increase IPV

198 grammatic adaptations and infants' uptake of inactivated poliovirus vaccine (IPV) after its introduct

199 ome differences in approach observed between inactivated poliovirus vaccine and bivalent OPV.

200 y lessons learned during the introduction of inactivated poliovirus vaccine in 3 countries that would

201 An inactivating promoter mutation, in contrast, obviates al

202 Ribosome inactivating proteins (RIPs) are RNA N-glycosidases that

203 Here we show that inactivated rabies virus particles containing the MERS-C

204 Here we generated recombinant inactivated rabies viruses that carry one of the CDV gly

205 A recent study employed a self-inactivating rabies (SiR) virus that enables recording o

206 These data establish that an inactivated RABV-MERS S-based vaccine may be effective f

207 we show that early activation of RhoA by S1P inactivates Rac1 but not Cdc42, and vice versa.

208 ctive Ras is bound to guanosine diphosphate, inactivating Ras.

209 unization of ferrets with beta-propiolactone-inactivated recombinant virus particles elicited protect

210 containing gamma2-subunit phosphorylated and inactivated RNA Pol I (polymerase I)-associated transcri

211 rat challenge model compared to formaldehyde inactivated RSV (FI-RSV) and live RSV experimental infec

212 observed in animals immunized with formalin-inactivated RSV.

213 infected intranasally with either RSV or UV-inactivated RSV.

214 prior to small pore formation by selectively inactivating sensitive Env glycoproteins, likely through

215 genomes contain an incomplete and apparently inactivated set of genes encoding the upper branch of me

216 im, we coupled mobilization of a single-copy inactivating Sleeping Beauty transposon to Pten disrupti

217 rts its effects by specifically cleaving and inactivating SNAP25.

218 ctures of the KcsA channel suggest that this inactivated state corresponds to a "constricted" conform

219 s unusual in binding selectively to the slow-inactivated state of sodium channels, in contrast to dru

220 filter corresponds to the functional C-type inactivated state of the KcsA.

221 iated with the irreversible transition to an inactivated state, as suggested by the Lumry-Eyring mode

222 sts that this receptor can exist in a deeply inactivated state, not responsive to ATP, and that its d

223 transition to accelerate entry into the slow inactivated state, resulting in use-dependent block.

224 nformation does not correspond to the C-type inactivated state.

225 are minimally essential for maintaining the inactivated state.

226 esults suggest that lacosamide binds to fast-inactivated states in a manner similar to other antiseiz

227 l, more consistent with slow binding to fast-inactivated states than selective binding to slow-inacti

228 The cycling of Navs through open, closed and inactivated states, and their closely choreographed rela

229 ignals were obtained in the resting and slow inactivated states.

230 ivated states than selective binding to slow-inactivated states.

231 ne and phenytoin, which bind tightly to fast-inactivated states.

232 tiepileptic drugs that bind to and stabilize inactivated states.

233 Using gene-inactivating studies in zebrafish and cell culture syste

234 A subset of these variants also suppressed inactivating substitutions in the signal peptide binding

235 tabolism and that itaconyl-CoA is a cofactor-inactivating, substrate-analog inhibitor of the mitochon

236 In this study, inactivated SwIV H1N2 antigens (KAg) encapsulated in PLG

237 PD-L1, inhibiting its binding to PD-1, which inactivates T cells.

238 Here, we inactivate the core component, Raptor, to show that mTOR

239 e higher oxidation states, which effectively inactivate the corresponding thiols and alter the electr

240 lipid fractions, is caused by mutations that inactivate the gene angiopoietin-like 3 (ANGPTL3).

241 he extended/open conformation to disorganize/inactivate the GTP binding/GTPase site.

242 and the Arg/N-end rule pathway cooperate to inactivate the LIN-28 pluripotency factor in seam cells,

243 IP is caused by pathogenic variants that inactivate the Nemo gene.

244 Conversely, rare variants that inactivate the NOS3 or GUCY1A3 genes were associated wit

245 ikely caused by altered GDP/GTP binding that inactivate the protein and induce GEF binding and protei

246 of genome editing in the brain to correct or inactivate the underlying genetic causes of neurological

247 V treatment is the inability to eradicate or inactivate the viral covalently closed circular DNA (ccc

248 -)DNA, which forms promutagenic uracils that inactivate the virus.

249 onsible for this phenotype, we insertionally inactivated the 14 annotated PTS EIIC-encoding genes in

250 Although H936A inactivated the lipid kinase activity without affecting

251 s on outcomes in the brain, we conditionally inactivated the murine Pten gene in neonatal neural stem

252 hile the aminopeptidase activity cleaves and inactivates the chemotactic tripeptide Pro-Gly-Pro.

253 is an anticoagulant serpin that irreversibly inactivates the clotting proteinases factor Xa and throm

254 hatase 1 (DUSP1), which dephosphorylates and inactivates the mitogen-activated protein kinases p38 an

255 PKCtheta selectively inactivates the negative regulator of F-actin generation

256 lation in lung cancer cells and tissues that inactivates the propaoptotic function of Bax, contributi

257 action appears to be sensory gating, because inactivating the central, basolateral, and lateral nucle

258 ed that XML inhibited the TAC-induced HF via inactivating the ERK1/2, AKT/GSK3beta, and GATA4 signali

259 ression promoted breast cancer malignancy by inactivating the Hippo signaling pathway and increasing

260 ive for the unmethylated tail and perturbing/inactivating the phosphatase active site.

261 CIN can be induced in the mouse by inactivating the spindle assembly checkpoint.

262 (2+)-dependent WPB exocytosis, presumably by inactivating the target Rab GTPases.

263 Is) regulate protease-mediated activities by inactivating their cognate proteinases, and are involved

264 gered immunity, and it is unclear how plants inactivate these effectors to execute the HR.

265 ce has proven to be an efficient strategy to inactivate TNFalpha, but the atomic-resolution mechanism

266 at both Syt1 and Syt2 need to be genetically inactivated to cause a significant reduction of activity

267 v1.7) that splicing modifies the return from inactivated to deactivated states, and the differences b

268 d immunosuppression that can be targeted and inactivated to improve the anticancer efficacy of PLN-de

269 ch the nuclear localization signal (NLS) was inactivated to prevent nuclear translocation of nBMP2 wh

270 inhibitory synapses and must be genetically inactivated together with Syt2 to achieve a significant

271 Conversely, under conditions that inactivate TORC2-Ypk1 signaling, which alleviates Fpk1 i

272 with low Ca(2+) potentiating and high Ca(2+) inactivating TRPA1.

273 etic events that activate proto-oncogenes or inactivate tumor-suppressor genes.

274 quences at their breakpoints and recurrently inactivated tumor-suppressor genes.

275 ansport activity to Tat signal peptides with inactivating twin arginine substitutions.

276 s, we applied RNA interference on mutants to inactivate two genes, used an imaging system to quantita

277 on with Uch37, but rather directly binds and inactivates Uch37.

278 that PAI-1 may regulate cardiac fibrosis by inactivating urokinase-type plasminogen activator (uPA)

279 lethal disease in N. vectensis and that heat-inactivated V. coralliilyticus and bacterial flagellin c

280 nd its priming immune responses with an H5N1 inactivated vaccine boost.

281 ve among children in a year with substantial inactivated vaccine effectiveness.

282 was 63% (95% CI, 45 to 75; P<0.001) for the inactivated vaccine, as compared with -19% (95% CI, -113

283 last vaccine received was live compared with inactivated vaccine, as well as concurrent receipt compa

284 as well as concurrent receipt compared with inactivated vaccine.

285 cally not as efficient as live attenuated or inactivated vaccines at inducing protective immune respo

286 etter cross-protective immune responses than inactivated vaccines by eliciting local mucosal immunity

287 ity but have reduced safety when compared to inactivated vaccines.

288 Cases had more rare inactivating variants in DNA repair genes than controls,

289 Self-inactivating vectors devoid of viral long-terminal-repea

290 nucleic acid (DNA and messenger RNA), whole-inactivated virus, live-attenuated or chimeric virus, an

291 L40, and we compared this vaccine to a whole-inactivated-virus vaccine (formaldehyde-inactivated HSV-

292 incident sunlight alter the ability of UV to inactivate waterborne pathogens.

293 mutants revealed that four of the five genes inactivated were required for stress survival.

294 Virus was inactivated when all three Env protomers were occupied b

295 dates have recently been described which use inactivated whole virus, DNA or RNA that express the vir

296 telangiectasia mutated (ATM)-p53 pathway is inactivated with relatively high frequency, leading to t

297 H3K27me3 and Xist RNA, only a subset of the inactivated X-linked genes is derepressed in Eed (-/-) T

298 y activates the Hippo pathway, which in turn inactivates YAP, leading to changes in the regulation of

299 We developed a purified formalin-inactivated Zika virus vaccine (ZPIV) candidate that sho

300 Immunogenicity and safety of inactivated zoster vaccine (ZVIN) were evaluated in adul