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   1 ording to the last vaccine type (live and/or inactivated).                                           
     2 appens in the SC when the FEF is temporarily inactivated.                                            
     3 reas genes of metazoan origin were primarily inactivated.                                            
     4 tood, little is known about how Igo/Ensa are inactivated.                                            
     5 family are mono-O-glucosylated and, thereby, inactivated.                                            
     6 trimer, and as a consequence the DHO is also inactivated.                                            
     7 bait in which the rabies vaccine was already inactivated.                                            
     8  after all three kinases were simultaneously inactivated.                                            
     9 ity disappeared when pxpA, pxpB, or pxpC was inactivated.                                            
    10 nucleotide translocator isoform 1 (ANT1) was inactivated.                                            
    11 e not nearly as catastrophic as when Mps1 is inactivated.                                            
    12 oniae cells when the aPBP synthase PBP1a was inactivated.                                            
    13 n the enzymatic activity of uricase had been inactivated.                                            
    14  disrupted when the medial frontal cortex is inactivated.                                            
    15 s in which endogenous Piezo1 was CRISPR/Cas9 inactivated.                                            
    16 ow clefts, mutant channels were incompletely inactivated.                                            
    17 ludge and sludge where the protozoa had been inactivated.                                            
    18 (VGKC) complex proteins, leucine-rich glioma-inactivated 1 (LGI1) and contactin-associated protein-2 
    19 extracellular domains of leucine-rich glioma-inactivated 1 (LGI1) and contactin-associated protein-li
    20 imbic encephalitis with leucine-rich, glioma-inactivated 1 (LGI1) antibodies is one of the most frequ
    21 esults from mutations in leucine-rich glioma-inactivated 1 (LGI1), a soluble glycoprotein secreted by
    22 omplex related proteins (leucine-rich glioma-inactivated 1 and contactin-associated protein-like 2), 
  
    24 four seminal studies that microstimulated or inactivated a key attention-related midbrain structure, 
  
  
    27 ho received live vaccine alone compared with inactivated alone or concurrent live and inactivated vac
  
  
  
  
    32 ion from the lysogenic to lytic state, CI is inactivated, and the two lytic promoters are de-represse
    33 monstrates the successful production of PERV-inactivated animals to address the safety concern in cli
    34 n the FRC environment where Cox-2 is genetic inactivated are more sensitive and rapidly activated upo
  
    36   Vaccination in pregnancy with a monovalent inactivated AS03-adjuvanted split virion influenza A(H1N
  
    38 hat carboxylic acids at these concentrations inactivated Ascaris eggs when the pH was below the pKa f
  
  
  
  
  
    44 ner (Control-NP) and a commercial adjuvanted inactivated BVDV vaccine (IAV), all inoculated subcutane
  
  
  
  
  
  
  
    52 g iron regulatory proteins IRP1 and IRP2 are inactivated by either Fe-S cluster insertion or protein 
    53 e response to HSV-1 and are also degraded or inactivated by ICP0, here we further investigate the rol
  
    55 ation of NAD(P)H, is upregulated when p16 is inactivated by looking at gene expression profiling stud
  
  
  
    59 MTs) in Arabidopsis thaliana are efficiently inactivated by phosphorylation to avoid toxic accumulati
  
  
  
  
    64 res of wild-type PRF and a sulfurtransferase-inactivated C314S mutant with and without glutathione we
  
    66 nt and functioning in vivo, we concomitantly inactivated CD4 and CD8 genes in mice with intact MHC cl
    67  Here, we describe a mouse model in which we inactivated Cic by selectively disabling its DNA-binding
  
    69 filter backbone in its collapsed deep C-type inactivated conformation, highlighting the close interac
    70 structures allow completion of a closed-open-inactivated conformational cycle in a single voltage-gat
    71 alation to A. fumigatus viable conidia, heat-inactivated conidia (HIC), or HEPA-filtered air twice a 
    72 nmt3a-Dnmt3L construct fused to the nuclease-inactivated dCas9 programmable targeting domain to intro
    73 mistry, against inactivation and rescues MCM inactivated during catalytic turnover by using the GTP-b
  
    75 nce with previous results, MDMs treated with inactivated EBOV and Ebola virus-like particles (VLPs) i
  
  
  
    79 reviously immunized with a nonlive, formalin-inactivated (FI)-RSV vaccine has been associated with se
    80  cultured using a combination of mitotically inactivated fibroblasts and Rho-associated protein kinas
    81 ed antihemagglutinin antibodies and seasonal inactivated flu vaccine (TIV) can elicit broadly protect
    82 T-independent 2 (TI-2) antigenic response to inactivated FMDV capsid.IMPORTANCE We have demonstrated 
    83 he sequential inoculation of three different inactivated FMDV serotypes (O, A, and Asia1 serotypes) a
  
    85 eric PntAB in Synechocystis sp. PCC 6803 was inactivated, followed by phenotypic and biophysical char
    86 d and unwinged aphids challenged with a heat-inactivated fungal pathogen, and found that immune costs
  
  
    89 ranscription and protein expression from the inactivated gene and the recovered organisms also expres
  
    91 lation was induced in cells infected with UV-inactivated HCMV, it was subsequently reduced, but not e
  
  
    94 mportantly, our data also suggest that LJ001-inactivated IHNV elicited an innate immune response in t
  
  
  
    98  of these genes (SLC39A14) was biallelically inactivated in a potentially treatable form of hypermang
  
   100 d a mouse line in which Pax6 was selectively inactivated in beta cells by crossing animals with floxe
   101 studies identify ADIPOR1 signaling, which is inactivated in both obesity and human cancers, as a key 
  
  
   104 diated apoptosis, for example, is frequently inactivated in human cancers via multiple mechanisms suc
   105 that lung-specific TFs become preferentially inactivated in lung cancer and precursor lung cancer les
  
  
  
   109 rotein p53, the "guardian of the genome", is inactivated in nearly all cancer types by mutations in t
   110 I/SNF (BAF) chromatin-remodeling complex, is inactivated in nearly all pediatric rhabdoid tumors.    
  
  
   113 ers have shown that the cystatin E/M gene is inactivated in primary human tumors, pointing to its rol
   114 of the products of a PKS mutant specifically inactivated in the dehydratase domain of extension-modul
   115   We identify TFs, such as AHR, which become inactivated in the earliest stages of lung cancer and wh
   116 se The von Hippel-Lindau tumor suppressor is inactivated in the majority of clear cell renal cell car
   117 Hippel-Lindau (VHL) tumor suppressor gene is inactivated in the majority of clear cell renal cell car
  
   119 anscriptional repressor that is specifically inactivated in the presence of formaldehyde, permitting 
   120 ction is dependent on p53, a protein that is inactivated in the vast majority of SCC tumors, leaving 
   121 nsgenic mice in which Tcf7l2 was selectively inactivated in their pancreatic pericytes exhibited impa
  
  
   124 imate the effectiveness of current and prior inactivated influenza A(H1N1)pdm09 vaccination from infl
   125 to four groups and received a single dose of inactivated influenza vaccine (fluvirin: 18 mug of haema
   126 ive attenuated influenza vaccine (LAIV) over inactivated influenza vaccine (IIV) among children aged 
   127 n 2011 and 2012 on the efficacy of trivalent inactivated influenza vaccine (IIV) during pregnancy wer
   128 luenza vaccine (LAIV) is more effective than inactivated influenza vaccine (IIV) in providing both di
   129 ing to evaluate vaccine efficacy of seasonal inactivated influenza vaccine (IIV) is controversial.   
   130 th a standard-dose, egg-grown, quadrivalent, inactivated influenza vaccine (IIV4) during the A/H3N2-p
   131 ith a standard-dose, egg-grown, quadrivalent-inactivated influenza vaccine (IIV4) for immunogenicity 
   132  coadministered with a quadrivalent seasonal inactivated influenza vaccine (IIV4) was investigated in
   133 are worker; or received a single dose of (4) inactivated influenza vaccine by microneedle patch self-
   134 cacy of maternal immunisation with trivalent inactivated influenza vaccine for protection of infants 
   135 Vaccination of pregnant women with trivalent inactivated influenza vaccine in Mali-a poorly resourced
   136  to receive seasonally recommended trivalent inactivated influenza vaccine or saline placebo in block
   137     Among children 2 to 17 years of age, the inactivated influenza vaccine was 60% effective (95% CI,
  
   139 enuated influenza vaccine, 11 (7 cRCTs) used inactivated influenza vaccine, and 5 (1 cRCT) compared b
  
  
  
  
  
  
  
   147  poly (I:C) was coated on a microneedle with inactivated influenza virus, and then immunized into BAL
   148 rams using live-attenuated oral (OPV) and/or inactivated (IPV) PV vaccines have systematically reduce
  
   150 however, an ATP-driven proton pump (Pma1) is inactivated, leading to a marked decrease in cytoplasmic
   151 /MST1 and STK3/MST2 in mammals), which, when inactivated, leads to considerable tissue overgrowth.   
  
   153  the colon environment, with the presence of inactivated microbiota resulting in a higher bioaccessib
   154 ivated at more hyperpolarized potentials and inactivated more slowly than it is in postnatal and adul
  
   156  describe the first substrate complex in the inactivated mutant form of PcCgkA at 1.7 A resolution.  
   157 after further digestion, as the irreversible inactivated myrosinase under gastric conditions caused n
  
  
  
  
  
  
   164 roxidase (POD) is an enzyme that needs to be inactivated or inhibited because of its deleterious effe
   165  both EBNA3A and EBNA3C can be conditionally inactivated or using virus completely lacking the EBNA3 
   166 porcine primary cell line and generated PERV-inactivated pigs via somatic cell nuclear transfer.     
   167 nding protein) is inserted into functionally-inactivated point mutants of two target proteins (staphy
   168 ndomly assigned to receive tOPV (n = 315) or inactivated polio vaccine (IPV) (n = 299) at 39 weeks.  
  
   170    Both Uganda and Indonesia have introduced inactivated polio vaccine (IPV) as part of the Global Po
   171 enhance immunity through the introduction of inactivated polio vaccine (IPV) in combination with OPV.
   172 he globally coordinated efforts to introduce inactivated polio vaccine (IPV) into all countries that 
  
  
   175 cine (OPV) only introduce at least 1 dose of Inactivated Polio Vaccine (IPV) into routine immunizatio
   176 d for the introduction of at least 1 dose of inactivated polio vaccine (IPV) into the routine immuniz
   177 o vaccine (OPV) introduce at least 1 dose of inactivated polio vaccine (IPV) into their routine immun
  
   179 tion systems using polio assets, introducing inactivated polio vaccine (IPV), and replacing trivalent
   180 third dose, and some vaccines, including the inactivated polio vaccine (IPV), must be injected more t
  
  
   183 virus-containing vaccine and introduction of inactivated polio vaccine in routine immunization to mit
   184 in storage and transportation capacity after inactivated polio vaccine introduction, but temperature 
  
   186 ses to booster doses of acellular pertussis, inactivated polio, and diphtheria vaccines at 12 to 24 m
   187 an 2013-2018-to introduce at least 1 dose of inactivated poliomyelitis vaccine (IPV); withdraw oral p
   188 immunity induced by oral poliovirus (OPV) or inactivated poliovirus (IPV) vaccines and mixed schedule
   189 y and safety of a novel monovalent high-dose inactivated poliovirus type 2 vaccine (mIPV2HD) in infan
  
  
   192 (one-fifth, 0.1 mL) intradermal doses of the inactivated poliovirus vaccine (ID fIPV) is positively c
   193 grammatic adaptations and infants' uptake of inactivated poliovirus vaccine (IPV) after its introduct
  
  
   196 ries required regulatory approval for use of inactivated poliovirus vaccine and bivalent OPV in routi
  
   198 y lessons learned during the introduction of inactivated poliovirus vaccine in 3 countries that would
   199 18, namely, (1) introduction of >/=1 dose of inactivated poliovirus vaccine in all 126 countries usin
   200 g with the type 2 component, introduction of inactivated poliovirus vaccine, strengthening of routine
  
   202 cine (diphtheria-tetanus-acellular pertussis-inactivated poliovirus/Haemophilus influenzae type b vac
  
  
   205 , combined with pharmacological block of ATP-inactivated potassium or stretch-activated cation-nonsel
   206 as the remarkable capability to survive with inactivated production of lipid A biosynthesis and the a
   207 f whom were positive for leucine-rich glioma-inactivated protein 1 [LGI1] Ab), and 4 (3.6%) had N-met
   208 antly enhance the function of DCs to present inactivated PRRSV antigen through TRIF/MyD88-NF-kappaB s
   209 ead-to-head comparison of recombinant versus inactivated quadrivalent influenza vaccines in 18-49 yea
  
  
  
  
   214  approach, we preferentially and efficiently inactivated RAF/ERK, upregulated BIM and down-regulated 
   215 unization of ferrets with beta-propiolactone-inactivated recombinant virus particles elicited protect
   216 not the case in cells exposed to live RESTV, inactivated RESTV, or VLPs containing RESTV GP, indicati
   217  In this study, we immunized mice with whole inactivated reverse genetics reassortant (RG) viruses ex
   218 containing gamma2-subunit phosphorylated and inactivated RNA Pol I (polymerase I)-associated transcri
   219 rat challenge model compared to formaldehyde inactivated RSV (FI-RSV) and live RSV experimental infec
  
  
   222  positioning remains unchanged when nmy-2 is inactivated, seam cell loss occurs through inappropriate
  
   224 genomes contain an incomplete and apparently inactivated set of genes encoding the upper branch of me
   225 th the structures associated with the closed-inactivated state (C/I) and in the well-known closed con
   226 ctures of the KcsA channel suggest that this inactivated state corresponds to a "constricted" conform
   227 s unusual in binding selectively to the slow-inactivated state of sodium channels, in contrast to dru
  
   229 iated with the irreversible transition to an inactivated state, as suggested by the Lumry-Eyring mode
   230 sts that this receptor can exist in a deeply inactivated state, not responsive to ATP, and that its d
   231 transition to accelerate entry into the slow inactivated state, resulting in use-dependent block.    
  
  
  
   235 esults suggest that lacosamide binds to fast-inactivated states in a manner similar to other antiseiz
   236 ther, our data suggest that the stability of inactivated states is under tight evolutionary control, 
   237 l, more consistent with slow binding to fast-inactivated states than selective binding to slow-inacti
   238 The cycling of Navs through open, closed and inactivated states, and their closely choreographed rela
  
  
  
  
  
  
  
   246 m samples from adults who received a dose of inactivated subunit vaccine (ISV) targeting monovalent 2
  
  
   249 onsible for this phenotype, we insertionally inactivated the 14 annotated PTS EIIC-encoding genes in 
  
  
   252  The S1565D phosphomimetic substitution also inactivated the kinase but did so without interfering wi
  
   254 s on outcomes in the brain, we conditionally inactivated the murine Pten gene in neonatal neural stem
   255 test this hypothesis, we pharmacogenetically inactivated the rhesus monkey amygdala, a subcortical re
  
  
  
   259 g a CRISPR-based approach, we systematically inactivated three of the most commonly mutated chromatin
   260 we confirm that UBA, UCA, and UEA are indeed inactivated through genetic defects at the promoter, whe
   261 led by phosphorylation; in particular, it is inactivated through phosphorylation by the TORC1 kinase 
   262 at both Syt1 and Syt2 need to be genetically inactivated to cause a significant reduction of activity
   263 v1.7) that splicing modifies the return from inactivated to deactivated states, and the differences b
   264 d immunosuppression that can be targeted and inactivated to improve the anticancer efficacy of PLN-de
   265 ch the nuclear localization signal (NLS) was inactivated to prevent nuclear translocation of nBMP2 wh
   266  inhibitory synapses and must be genetically inactivated together with Syt2 to achieve a significant 
  
   268 arallel mechanisms and at proteasomes, RA190-inactivated Uch37 cannot disassemble hRpn13-bound ubiqui
   269 lethal disease in N. vectensis and that heat-inactivated V. coralliilyticus and bacterial flagellin c
  
  
   272 onstrated that mice receiving a conventional inactivated vaccine followed by a skin-applied dissolvin
   273  was 63% (95% CI, 45 to 75; P<0.001) for the inactivated vaccine, as compared with -19% (95% CI, -113
   274 last vaccine received was live compared with inactivated vaccine, as well as concurrent receipt compa
  
  
   277 ith inactivated alone or concurrent live and inactivated vaccines (HR, 0.50; 95% confidence interval 
   278   Separate estimates were calculated for the inactivated vaccines and the live attenuated vaccine.   
   279 cally not as efficient as live attenuated or inactivated vaccines at inducing protective immune respo
   280 etter cross-protective immune responses than inactivated vaccines by eliciting local mucosal immunity
   281 ctively) and for those who received live and inactivated vaccines concurrently compared with inactiva
  
  
  
  
   286  nucleic acid (DNA and messenger RNA), whole-inactivated virus, live-attenuated or chimeric virus, an
   287 L40, and we compared this vaccine to a whole-inactivated-virus vaccine (formaldehyde-inactivated HSV-
  
  
   290 dates have recently been described which use inactivated whole virus, DNA or RNA that express the vir
  
   292 riptome uncovered immune molecules activated/inactivated with aging and identified the silencing of t
   293  telangiectasia mutated (ATM)-p53 pathway is inactivated with relatively high frequency, leading to t
   294 pores, show that each pore can be separately inactivated without blocking F(-) conduction through its
   295  H3K27me3 and Xist RNA, only a subset of the inactivated X-linked genes is derepressed in Eed (-/-) T
   296 hat one of the two X chromosomes is randomly inactivated, X-SPINK1 mice exhibit mosaic pattern of SPI
  
  
  
  
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