ライフサイエンスコーパス: inactivation curve

1 r an additional hyperpolarizing shift of the inactivation curve.

2 ated state and a hyperpolarized steady-state inactivation curve.

3 ctivation curve of I(A) without altering the inactivation curve.

4 nificant, negative shift of the steady-state inactivation curve.

5 ionship but produced a negative shift in the inactivation curve.

6 tion causes a dramatic positive shift of the inactivation curve.

7 erimposed after voltage shifting, as did the inactivation curves.

8 position of the activation and steady state inactivation curves.

9 ss of the sodium current, while shifting the inactivation curve ~10 mV toward more hyperpolarized pot

10 shift of the voltage-dependent steady-state inactivation curve, a slower inactivation, and a faster

11 l overlap of its activation and steady-state inactivation curves and its persistent nature suggest th

12 curves negative, decreasing the slope of the inactivation curve, and increasing the percentage of non

13 protocols (such as I-V curves, steady-state inactivation curves, and measurements of inactivation ra

14 g, shifting both steady state activation and inactivation curves, as well as accelerating channel kin

15 the midpotential of the hKv2.1 steady-state inactivation curve by approx. 15 mV in the hyperpolarizi

16 a hyperpolarizing shift in the steady-state inactivation curve completely abolished EADs in myocytes

17 The trace of the inactivation curve could not be altered by preincubating

18 current" between the voltage activation and inactivation curves, decreasing the tonically active I(A

19 s dominating and, consequently, the prepulse inactivation curves exhibit depolarizing shifts (DeltaV

20 tion in inside-out patches, the steady-state inactivation curve exhibits a hyperpolarizing shift of a

21 a hyperpolarizing shift in the steady-state inactivation curve for the sodium current.

22 nt-voltage relationship and the steady-state inactivation curve for the TTX-R INa which were indistin

23 When steady-state inactivation curves for the L current were fitted with a

24 oltage-dependent activation and steady-state inactivation curves for these currents were shifted nega

25 polarizing shift in the apparent Na+ channel inactivation curves generated from Vmax and theta2, resp

26 urrents at rest and shifted the steady-state inactivation curve (h infinity) toward the hyperpolarizi

27 s altered the shape of the voltage-dependent inactivation curve indicating that the suppression of IK

28 d in the depolarized direction, and the fast-inactivation curve is less steep compared with mu1.

29 ate constants by as much as 600%, shortening inactivation curve lag phase by up to 73% and lowering C

30 -93 shifted the midpoint of the steady-state inactivation curve leftward and markedly slowed the reco

31 In addition, we find that the steady-state inactivation curve of modified Na channels is made much

32 The steady-state inactivation curve of Na(v)1.2a was shifted +12 mV in Na

33 hat from control rats (109.4 pA/pF), and the inactivation curve of the IA current was displaced to mo

34 effects on the position of the steady state inactivation curve of the Kv4.3 channel.

35 dings revealed a hyperpolarized shift in the inactivation curve of transient, A-type K(+) currents th

36 As a consequence, the activation and inactivation curves of ASIC3 but not other ASICs overlap

37 cantly increased at 38 h after ischemia; the inactivation curves of I(A) shifted toward the depolariz

38 ation, shifts of steady-state activation and inactivation curves of I(Na) to more depolarized potenti

39 Activation and inactivation curves of ICa currents in cells expressing

40 t density, and right-shifted the V1/2 of the inactivation curve, of hindpaw innervating DRG neurons,

41 g peptides caused depolarizing shifts in the inactivation curves seen with CaM(WT) coexpression with

42 y-state channel availability relationships ("inactivation curves") shifted toward more negative membr

43 Activation and inactivation curves showed no shift in the voltage depen

44 to changes in the steady-state activation or inactivation curves, the time course of current decay, t

45 o higher pH values and a slight shift of the inactivation curve to lower pH values.

46 in the rate of inactivation and shifted the inactivation curve to more hyperpolarized potentials, bu

47 eduction of I(Ca,L) density and shift of the inactivation curves to more depolarized potentials).

48 near 0 mV and shifted the Na+ activation and inactivation curves to the left.

49 ss acidic pH but a shift in the steady state inactivation curve toward more acidic pH.

50 The midpoint of the steady-state inactivation curve was approximately 25 mV more negative

51 The midpoints of steady-state activation and inactivation curves were 1.1 mV and -61.4 mV, respective

52 ches, respectively, n = 16, P < 0.01), while inactivation curves were not significantly different.

53 ng measurements, bell-shaped Ca2+ activation/inactivation curves were obtained in media containing di

54 Steady-state inactivation curves were shifted by approximately 10 mV

55 Steady-state inactivation curves were shifted to more depolarized pot

56 Steady-state inactivation curves were similar in the two populations.

57 depolarizing shift of the steady-state fast inactivation curve, whereas EE1314,15RR produced a hyper